Motif ID: EBF1

Z-value: 0.977


Transcription factors associated with EBF1:

Gene SymbolEntrez IDGene Name
EBF1 ENSG00000164330.12 EBF1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
EBF1hg19_v2_chr5_-_158526756_1585267970.174.4e-01Click!


Activity profile for motif EBF1.

activity profile for motif EBF1


Sorted Z-values histogram for motif EBF1

Sorted Z-values for motif EBF1



Network of associatons between targets according to the STRING database.



First level regulatory network of EBF1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_+_111889212 1.516 ENST00000369737.4
PIFO
primary cilia formation
chr16_-_67427389 1.365 ENST00000562206.1
ENST00000290942.5
ENST00000393957.2
TPPP3


tubulin polymerization-promoting protein family member 3


chr5_-_149792295 1.212 ENST00000518797.1
ENST00000524315.1
ENST00000009530.7
ENST00000377795.3
CD74



CD74 molecule, major histocompatibility complex, class II invariant chain



chr1_+_118148556 1.123 ENST00000369448.3
FAM46C
family with sequence similarity 46, member C
chr14_+_105953204 1.113 ENST00000409393.2
CRIP1
cysteine-rich protein 1 (intestinal)
chr14_+_105953246 1.076 ENST00000392531.3
CRIP1
cysteine-rich protein 1 (intestinal)
chr19_+_50706866 1.055 ENST00000440075.2
ENST00000376970.2
ENST00000425460.1
ENST00000599920.1
ENST00000601313.1
MYH14




myosin, heavy chain 14, non-muscle




chr15_+_74610894 1.052 ENST00000558821.1
ENST00000268082.4
CCDC33

coiled-coil domain containing 33

chr11_+_827553 1.051 ENST00000528542.2
ENST00000450448.1
EFCAB4A

EF-hand calcium binding domain 4A

chr11_+_111385497 1.038 ENST00000375618.4
ENST00000529167.1
ENST00000332814.6
C11orf88


chromosome 11 open reading frame 88


chr14_-_100625932 1.008 ENST00000553834.1
DEGS2
delta(4)-desaturase, sphingolipid 2
chr7_-_99573640 0.988 ENST00000411734.1
AZGP1
alpha-2-glycoprotein 1, zinc-binding
chr2_-_241497374 0.985 ENST00000373318.2
ENST00000406958.1
ENST00000391987.1
ENST00000373320.4
ANKMY1



ankyrin repeat and MYND domain containing 1



chr16_-_21289627 0.975 ENST00000396023.2
ENST00000415987.2
CRYM

crystallin, mu

chr14_-_21270995 0.969 ENST00000555698.1
ENST00000397970.4
ENST00000340900.3
RNASE1


ribonuclease, RNase A family, 1 (pancreatic)


chr14_+_22984601 0.912 ENST00000390509.1
TRAJ28
T cell receptor alpha joining 28
chr6_+_19837592 0.891 ENST00000378700.3
ID4
inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
chr17_+_4981535 0.866 ENST00000318833.3
ZFP3
ZFP3 zinc finger protein
chr10_-_100027943 0.865 ENST00000260702.3
LOXL4
lysyl oxidase-like 4
chr16_-_67260691 0.848 ENST00000447579.1
ENST00000393992.1
ENST00000424285.1
LRRC29


leucine rich repeat containing 29



Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 451 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.8 3.9 GO:0060741 prostate gland stromal morphogenesis(GO:0060741)
0.0 2.4 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.1 1.8 GO:0044458 motile cilium assembly(GO:0044458)
0.3 1.7 GO:1990822 basic amino acid transmembrane transport(GO:1990822)
0.1 1.7 GO:0006068 ethanol catabolic process(GO:0006068)
0.2 1.5 GO:0010734 protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734)
0.3 1.4 GO:0072313 metanephric glomerular epithelium development(GO:0072244) metanephric glomerular visceral epithelial cell differentiation(GO:0072248) metanephric glomerular visceral epithelial cell development(GO:0072249) metanephric glomerular epithelial cell differentiation(GO:0072312) metanephric glomerular epithelial cell development(GO:0072313)
0.2 1.4 GO:0045007 depurination(GO:0045007)
0.0 1.4 GO:0071625 vocalization behavior(GO:0071625)
0.2 1.3 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.0 1.3 GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.2 1.2 GO:0002901 mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906)
0.2 1.2 GO:0030382 sperm mitochondrion organization(GO:0030382)
0.1 1.2 GO:0009437 carnitine metabolic process(GO:0009437)
0.0 1.2 GO:0035082 axoneme assembly(GO:0035082)
0.0 1.2 GO:0048741 skeletal muscle fiber development(GO:0048741)
0.4 1.1 GO:1904395 positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395)
0.0 1.1 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 1.1 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.3 1.0 GO:0006667 sphinganine metabolic process(GO:0006667)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 131 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.5 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 1.5 GO:0036064 ciliary basal body(GO:0036064)
0.1 1.3 GO:0097227 sperm annulus(GO:0097227)
0.1 1.3 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.1 1.1 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 1.0 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 1.0 GO:0101003 ficolin-1-rich granule membrane(GO:0101003)
0.3 0.9 GO:0005608 laminin-3 complex(GO:0005608)
0.1 0.9 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.1 0.9 GO:1990111 spermatoproteasome complex(GO:1990111)
0.1 0.9 GO:0044292 dendrite terminus(GO:0044292)
0.0 0.9 GO:0030673 axolemma(GO:0030673)
0.0 0.9 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.9 GO:0035577 azurophil granule membrane(GO:0035577)
0.2 0.8 GO:0097513 myosin II filament(GO:0097513)
0.1 0.7 GO:0097512 cardiac myofibril(GO:0097512)
0.0 0.7 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.7 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.7 GO:0030660 Golgi-associated vesicle membrane(GO:0030660)
0.1 0.6 GO:0031501 mannosyltransferase complex(GO:0031501)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 280 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.3 GO:0003680 AT DNA binding(GO:0003680)
0.0 2.2 GO:0048487 beta-tubulin binding(GO:0048487)
0.1 1.6 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.2 1.5 GO:0004522 ribonuclease A activity(GO:0004522)
0.1 1.5 GO:0004017 adenylate kinase activity(GO:0004017)
0.4 1.4 GO:0032408 MutLbeta complex binding(GO:0032406) MutSbeta complex binding(GO:0032408)
0.1 1.4 GO:0019864 IgG binding(GO:0019864)
0.0 1.4 GO:0070840 dynein complex binding(GO:0070840)
0.3 1.3 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.1 1.3 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 1.3 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 1.3 GO:0030507 spectrin binding(GO:0030507)
0.0 1.2 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 1.2 GO:0030552 cAMP binding(GO:0030552)
0.1 1.1 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.2 1.0 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.2 1.0 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 1.0 GO:0008320 protein transmembrane transporter activity(GO:0008320)
0.1 0.9 GO:0050294 flavonol 3-sulfotransferase activity(GO:0047894) steroid sulfotransferase activity(GO:0050294)
0.1 0.9 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)

Gene overrepresentation in C2:CP category:

Showing 1 to 20 of 20 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.6 ST_WNT_CA2_CYCLIC_GMP_PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 1.1 PID_CD8_TCR_PATHWAY TCR signaling in naïve CD8+ T cells
0.0 0.7 PID_BMP_PATHWAY BMP receptor signaling
0.0 0.6 PID_SYNDECAN_3_PATHWAY Syndecan-3-mediated signaling events
0.0 0.6 PID_EPHA_FWDPATHWAY EPHA forward signaling
0.0 0.6 PID_PS1_PATHWAY Presenilin action in Notch and Wnt signaling
0.0 0.6 PID_HDAC_CLASSII_PATHWAY Signaling events mediated by HDAC Class II
0.0 0.5 PID_RHODOPSIN_PATHWAY Visual signal transduction: Rods
0.0 0.5 ST_MYOCYTE_AD_PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 0.4 PID_AMB2_NEUTROPHILS_PATHWAY amb2 Integrin signaling
0.0 0.4 PID_IL27_PATHWAY IL27-mediated signaling events
0.0 0.3 ST_G_ALPHA_I_PATHWAY G alpha i Pathway
0.0 0.2 PID_ECADHERIN_KERATINOCYTE_PATHWAY E-cadherin signaling in keratinocytes
0.0 0.2 PID_TXA2PATHWAY Thromboxane A2 receptor signaling
0.0 0.2 PID_ALK2_PATHWAY ALK2 signaling events
0.0 0.2 PID_INTEGRIN_A4B1_PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.1 ST_ADRENERGIC Adrenergic Pathway
0.0 0.1 PID_INSULIN_PATHWAY Insulin Pathway
0.0 0.1 PID_SYNDECAN_4_PATHWAY Syndecan-4-mediated signaling events
0.0 0.1 PID_RANBP2_PATHWAY Sumoylation by RanBP2 regulates transcriptional repression

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 20 of 54 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.1 REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 1.8 REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 1.6 REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1 1.4 REACTOME_BASE_FREE_SUGAR_PHOSPHATE_REMOVAL_VIA_THE_SINGLE_NUCLEOTIDE_REPLACEMENT_PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 1.3 REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 1.2 REACTOME_CYTOSOLIC_SULFONATION_OF_SMALL_MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 1.1 REACTOME_SYNTHESIS_OF_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 1.1 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 1.0 REACTOME_ORGANIC_CATION_ANION_ZWITTERION_TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.9 REACTOME_REGULATION_OF_COMPLEMENT_CASCADE Genes involved in Regulation of Complement cascade
0.0 0.9 REACTOME_INHIBITION_OF_VOLTAGE_GATED_CA2_CHANNELS_VIA_GBETA_GAMMA_SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.9 REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.9 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.8 REACTOME_TRANSLOCATION_OF_ZAP_70_TO_IMMUNOLOGICAL_SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 0.8 REACTOME_GLUTATHIONE_CONJUGATION Genes involved in Glutathione conjugation
0.0 0.8 REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.8 REACTOME_CYTOCHROME_P450_ARRANGED_BY_SUBSTRATE_TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.8 REACTOME_INTERFERON_ALPHA_BETA_SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.7 REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.7 REACTOME_SIGNALING_BY_NODAL Genes involved in Signaling by NODAL