Motif ID: EBF3

Z-value: 0.493


Transcription factors associated with EBF3:

Gene SymbolEntrez IDGene Name
EBF3 ENSG00000108001.9 EBF3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
EBF3hg19_v2_chr10_-_131762105_131762105-0.116.0e-01Click!


Activity profile for motif EBF3.

activity profile for motif EBF3


Sorted Z-values histogram for motif EBF3

Sorted Z-values for motif EBF3



Network of associatons between targets according to the STRING database.



First level regulatory network of EBF3

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chrX_+_38420783 0.801 ENST00000422612.2
ENST00000286824.6
ENST00000545599.1
TSPAN7


tetraspanin 7


chr1_-_204116078 0.798 ENST00000367198.2
ENST00000452983.1
ETNK2

ethanolamine kinase 2

chr16_-_85784718 0.692 ENST00000602766.1
C16orf74
chromosome 16 open reading frame 74
chr15_+_90728145 0.675 ENST00000561085.1
ENST00000379122.3
ENST00000332496.6
SEMA4B


sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B


chr16_-_85784557 0.650 ENST00000602675.1
C16orf74
chromosome 16 open reading frame 74
chr16_-_85784634 0.639 ENST00000284245.4
ENST00000602914.1
C16orf74

chromosome 16 open reading frame 74

chr10_+_11784360 0.617 ENST00000379215.4
ENST00000420401.1
ECHDC3

enoyl CoA hydratase domain containing 3

chr22_-_37640277 0.611 ENST00000401529.3
ENST00000249071.6
RAC2

ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)

chr10_+_77056134 0.610 ENST00000528121.1
ENST00000416398.1
ZNF503-AS1

ZNF503 antisense RNA 1

chr5_-_146833222 0.592 ENST00000534907.1
DPYSL3
dihydropyrimidinase-like 3
chr5_-_146833485 0.581 ENST00000398514.3
DPYSL3
dihydropyrimidinase-like 3
chrX_+_69509927 0.566 ENST00000374403.3
KIF4A
kinesin family member 4A
chr22_-_37640456 0.563 ENST00000405484.1
ENST00000441619.1
ENST00000406508.1
RAC2


ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)


chr11_+_111126707 0.520 ENST00000280325.4
C11orf53
chromosome 11 open reading frame 53
chrX_+_38420623 0.500 ENST00000378482.2
TSPAN7
tetraspanin 7
chr1_-_26197744 0.497 ENST00000374296.3
PAQR7
progestin and adipoQ receptor family member VII
chr3_-_189840223 0.491 ENST00000427335.2
LEPREL1
leprecan-like 1
chr5_+_154393260 0.483 ENST00000435029.4
KIF4B
kinesin family member 4B
chr16_+_67233007 0.477 ENST00000360833.1
ENST00000393997.2
ELMO3

engulfment and cell motility 3

chr3_-_145878954 0.467 ENST00000282903.5
ENST00000360060.3
PLOD2

procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2

chr18_+_34124507 0.435 ENST00000591635.1
FHOD3
formin homology 2 domain containing 3
chr6_-_30654977 0.424 ENST00000399199.3
PPP1R18
protein phosphatase 1, regulatory subunit 18
chr12_+_53443680 0.419 ENST00000314250.6
ENST00000451358.1
TENC1

tensin like C1 domain containing phosphatase (tensin 2)

chr12_+_53443963 0.416 ENST00000546602.1
ENST00000552570.1
ENST00000549700.1
TENC1


tensin like C1 domain containing phosphatase (tensin 2)


chrX_-_48827976 0.399 ENST00000218176.3
KCND1
potassium voltage-gated channel, Shal-related subfamily, member 1
chr17_-_39553844 0.387 ENST00000251645.2
KRT31
keratin 31
chr3_-_59035673 0.385 ENST00000491845.1
ENST00000472469.1
ENST00000471288.1
ENST00000295966.7
C3orf67



chromosome 3 open reading frame 67



chr8_-_6735451 0.363 ENST00000297439.3
DEFB1
defensin, beta 1
chr3_+_100211412 0.356 ENST00000323523.4
ENST00000403410.1
ENST00000449609.1
TMEM45A


transmembrane protein 45A


chr2_-_31361543 0.351 ENST00000349752.5
GALNT14
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 14 (GalNAc-T14)
chr1_-_159924006 0.347 ENST00000368092.3
ENST00000368093.3
SLAMF9

SLAM family member 9

chr11_-_66104237 0.342 ENST00000530056.1
RIN1
Ras and Rab interactor 1
chr17_+_39975544 0.342 ENST00000544340.1
FKBP10
FK506 binding protein 10, 65 kDa
chr1_+_3388181 0.335 ENST00000418137.1
ENST00000413250.2
ARHGEF16

Rho guanine nucleotide exchange factor (GEF) 16

chr1_+_23695680 0.331 ENST00000454117.1
ENST00000335648.3
ENST00000518821.1
ENST00000437367.2
C1orf213



chromosome 1 open reading frame 213



chr14_+_101193246 0.330 ENST00000331224.6
DLK1
delta-like 1 homolog (Drosophila)
chr14_+_101193164 0.329 ENST00000341267.4
DLK1
delta-like 1 homolog (Drosophila)
chr17_+_39975455 0.329 ENST00000455106.1
FKBP10
FK506 binding protein 10, 65 kDa
chr19_+_39904168 0.328 ENST00000438123.1
ENST00000409797.2
ENST00000451354.2
PLEKHG2


pleckstrin homology domain containing, family G (with RhoGef domain) member 2


chr5_+_176237478 0.321 ENST00000329542.4
UNC5A
unc-5 homolog A (C. elegans)
chr1_-_156828810 0.320 ENST00000368195.3
INSRR
insulin receptor-related receptor
chr19_+_54369608 0.313 ENST00000336967.3
MYADM
myeloid-associated differentiation marker
chr10_+_99332529 0.306 ENST00000455090.1
ANKRD2
ankyrin repeat domain 2 (stretch responsive muscle)
chr7_+_48128194 0.302 ENST00000416681.1
ENST00000331803.4
ENST00000432131.1
UPP1


uridine phosphorylase 1


chr16_+_67233412 0.301 ENST00000477898.1
ELMO3
engulfment and cell motility 3
chr3_-_16524357 0.299 ENST00000432519.1
RFTN1
raftlin, lipid raft linker 1
chr7_+_48128316 0.298 ENST00000341253.4
UPP1
uridine phosphorylase 1
chr11_+_124735282 0.295 ENST00000397801.1
ROBO3
roundabout, axon guidance receptor, homolog 3 (Drosophila)
chr19_+_47105309 0.291 ENST00000599839.1
ENST00000596362.1
CALM3

calmodulin 3 (phosphorylase kinase, delta)

chr19_+_41107249 0.280 ENST00000396819.3
LTBP4
latent transforming growth factor beta binding protein 4
chr11_-_67120974 0.278 ENST00000539074.1
ENST00000312419.3
POLD4

polymerase (DNA-directed), delta 4, accessory subunit

chr2_+_220325441 0.274 ENST00000396688.1
SPEG
SPEG complex locus
chr1_-_154943212 0.272 ENST00000368445.5
ENST00000448116.2
ENST00000368449.4
SHC1


SHC (Src homology 2 domain containing) transforming protein 1


chr1_+_153747746 0.271 ENST00000368661.3
SLC27A3
solute carrier family 27 (fatty acid transporter), member 3
chr10_+_99332198 0.270 ENST00000307518.5
ENST00000298808.5
ENST00000370655.1
ANKRD2


ankyrin repeat domain 2 (stretch responsive muscle)


chr22_+_21321531 0.260 ENST00000405089.1
ENST00000335375.5
AIFM3

apoptosis-inducing factor, mitochondrion-associated, 3

chr1_-_41950342 0.259 ENST00000372587.4
EDN2
endothelin 2
chr14_+_55034330 0.258 ENST00000251091.5
SAMD4A
sterile alpha motif domain containing 4A
chr1_-_154943002 0.257 ENST00000606391.1
SHC1
SHC (Src homology 2 domain containing) transforming protein 1
chr16_+_77225071 0.255 ENST00000439557.2
ENST00000545553.1
MON1B

MON1 secretory trafficking family member B

chr14_+_55034599 0.255 ENST00000392067.3
ENST00000357634.3
SAMD4A

sterile alpha motif domain containing 4A

chr10_+_102106829 0.251 ENST00000370355.2
SCD
stearoyl-CoA desaturase (delta-9-desaturase)
chr17_-_7493390 0.248 ENST00000538513.2
ENST00000570788.1
ENST00000250055.2
SOX15


SRY (sex determining region Y)-box 15


chr17_-_1395954 0.246 ENST00000359786.5
MYO1C
myosin IC
chr14_-_106586656 0.240 ENST00000390602.2
IGHV3-13
immunoglobulin heavy variable 3-13
chr17_-_34890759 0.240 ENST00000431794.3
MYO19
myosin XIX
chr2_+_220325977 0.239 ENST00000396686.1
ENST00000396689.2
SPEG

SPEG complex locus

chr11_+_65408273 0.238 ENST00000394227.3
SIPA1
signal-induced proliferation-associated 1
chr6_+_43737939 0.237 ENST00000372067.3
VEGFA
vascular endothelial growth factor A
chr19_-_14224969 0.232 ENST00000589994.1
PRKACA
protein kinase, cAMP-dependent, catalytic, alpha
chr6_+_43738444 0.228 ENST00000324450.6
ENST00000417285.2
ENST00000413642.3
ENST00000372055.4
ENST00000482630.2
ENST00000425836.2
ENST00000372064.4
ENST00000372077.4
ENST00000519767.1
VEGFA








vascular endothelial growth factor A








chr17_+_73452545 0.225 ENST00000314256.7
KIAA0195
KIAA0195
chr17_-_34890732 0.225 ENST00000268852.9
MYO19
myosin XIX
chr1_+_32084794 0.225 ENST00000373705.1
HCRTR1
hypocretin (orexin) receptor 1
chr12_+_119616447 0.221 ENST00000281938.2
HSPB8
heat shock 22kDa protein 8
chr19_-_19051103 0.220 ENST00000542541.2
ENST00000433218.2
HOMER3

homer homolog 3 (Drosophila)

chr11_+_64058758 0.220 ENST00000538767.1
KCNK4
potassium channel, subfamily K, member 4
chr9_+_135854091 0.219 ENST00000450530.1
ENST00000534944.1
GFI1B

growth factor independent 1B transcription repressor

chr3_+_5020801 0.218 ENST00000256495.3
BHLHE40
basic helix-loop-helix family, member e40
chr12_-_772901 0.209 ENST00000305108.4
NINJ2
ninjurin 2
chr11_-_62446527 0.209 ENST00000294119.2
ENST00000529640.1
ENST00000534176.1
ENST00000301935.5
UBXN1



UBX domain protein 1



chr18_-_72920372 0.209 ENST00000581620.1
ENST00000582437.1
ZADH2

zinc binding alcohol dehydrogenase domain containing 2

chr11_+_64058820 0.204 ENST00000422670.2
KCNK4
potassium channel, subfamily K, member 4
chr7_+_132333553 0.203 ENST00000332558.4
AC009365.3
AC009365.3
chr16_-_33647696 0.200 ENST00000558425.1
ENST00000569103.2
RP11-812E19.9

Uncharacterized protein

chr12_-_123215306 0.197 ENST00000356987.2
ENST00000436083.2
HCAR1

hydroxycarboxylic acid receptor 1

chrX_+_105937068 0.195 ENST00000324342.3
RNF128
ring finger protein 128, E3 ubiquitin protein ligase
chr1_+_109792641 0.193 ENST00000271332.3
CELSR2
cadherin, EGF LAG seven-pass G-type receptor 2
chr14_-_106791536 0.189 ENST00000390613.2
IGHV3-30
immunoglobulin heavy variable 3-30
chr6_+_31555045 0.188 ENST00000396101.3
ENST00000490742.1
LST1

leukocyte specific transcript 1

chr12_+_7282795 0.186 ENST00000266546.6
CLSTN3
calsyntenin 3
chrX_+_48367338 0.185 ENST00000359882.4
ENST00000537758.1
ENST00000367574.4
ENST00000355961.4
ENST00000489940.1
ENST00000361988.3
PORCN





porcupine homolog (Drosophila)





chr16_-_30102547 0.184 ENST00000279386.2
TBX6
T-box 6
chr15_+_74218787 0.184 ENST00000261921.7
LOXL1
lysyl oxidase-like 1
chr6_-_10419871 0.184 ENST00000319516.4
TFAP2A
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr10_+_88428206 0.184 ENST00000429277.2
ENST00000458213.2
ENST00000352360.5
LDB3


LIM domain binding 3


chrX_-_74376108 0.183 ENST00000339447.4
ENST00000373394.3
ENST00000529949.1
ENST00000534524.1
ENST00000253577.3
ABCB7




ATP-binding cassette, sub-family B (MDR/TAP), member 7




chr19_-_38743878 0.182 ENST00000587515.1
PPP1R14A
protein phosphatase 1, regulatory (inhibitor) subunit 14A
chr22_+_38201114 0.180 ENST00000340857.2
H1F0
H1 histone family, member 0
chr11_+_130318869 0.179 ENST00000299164.2
ADAMTS15
ADAM metallopeptidase with thrombospondin type 1 motif, 15
chr7_+_77167343 0.178 ENST00000433369.2
ENST00000415482.2
PTPN12

protein tyrosine phosphatase, non-receptor type 12

chr16_+_30960375 0.177 ENST00000318663.4
ENST00000566237.1
ENST00000562699.1
ORAI3


ORAI calcium release-activated calcium modulator 3


chr11_-_7961141 0.177 ENST00000360759.3
OR10A3
olfactory receptor, family 10, subfamily A, member 3
chr10_+_99344104 0.177 ENST00000555577.1
ENST00000370649.3
PI4K2A
PI4K2A
phosphatidylinositol 4-kinase type 2 alpha
Phosphatidylinositol 4-kinase type 2-alpha; Uncharacterized protein
chr2_-_219151487 0.176 ENST00000444881.1
TMBIM1
transmembrane BAX inhibitor motif containing 1
chr3_-_120003941 0.175 ENST00000464295.1
GPR156
G protein-coupled receptor 156
chr7_+_116593953 0.174 ENST00000397750.3
ST7-OT4
ST7 overlapping transcript 4
chrX_-_153637612 0.174 ENST00000369807.1
ENST00000369808.3
DNASE1L1

deoxyribonuclease I-like 1

chr17_-_34890709 0.173 ENST00000544606.1
MYO19
myosin XIX
chr5_+_3596168 0.171 ENST00000302006.3
IRX1
iroquois homeobox 1
chr17_+_38465441 0.170 ENST00000577646.1
ENST00000254066.5
RARA

retinoic acid receptor, alpha

chr13_-_30881621 0.168 ENST00000380615.3
KATNAL1
katanin p60 subunit A-like 1
chr5_+_149569520 0.168 ENST00000230671.2
ENST00000524041.1
SLC6A7

solute carrier family 6 (neurotransmitter transporter), member 7

chr1_+_161719552 0.164 ENST00000367943.4
DUSP12
dual specificity phosphatase 12
chr16_+_30671223 0.162 ENST00000568722.1
FBRS
fibrosin
chr10_+_122357721 0.161 ENST00000369071.2
C10orf85
chromosome 10 open reading frame 85
chr11_+_124932986 0.161 ENST00000407458.1
ENST00000298280.5
SLC37A2

solute carrier family 37 (glucose-6-phosphate transporter), member 2

chr11_+_124933191 0.160 ENST00000532000.1
ENST00000308074.4
SLC37A2

solute carrier family 37 (glucose-6-phosphate transporter), member 2

chr11_+_124932955 0.158 ENST00000403796.2
SLC37A2
solute carrier family 37 (glucose-6-phosphate transporter), member 2
chr12_+_8662057 0.158 ENST00000382064.2
CLEC4D
C-type lectin domain family 4, member D
chr16_-_67867749 0.158 ENST00000566758.1
ENST00000445712.2
ENST00000219172.3
ENST00000564817.1
CENPT



centromere protein T



chr5_+_159656437 0.157 ENST00000402432.3
FABP6
fatty acid binding protein 6, ileal
chr18_-_72921303 0.156 ENST00000322342.3
ZADH2
zinc binding alcohol dehydrogenase domain containing 2
chr1_+_43282782 0.156 ENST00000372517.2
ERMAP
erythroblast membrane-associated protein (Scianna blood group)
chr5_-_180669236 0.156 ENST00000507756.1
GNB2L1
guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1
chr1_-_159915386 0.152 ENST00000361509.3
ENST00000368094.1
IGSF9

immunoglobulin superfamily, member 9

chr7_+_77167376 0.149 ENST00000435495.2
PTPN12
protein tyrosine phosphatase, non-receptor type 12
chr1_-_242612779 0.147 ENST00000427495.1
PLD5
phospholipase D family, member 5
chr7_-_100881109 0.146 ENST00000308344.5
CLDN15
claudin 15
chr19_+_35634146 0.146 ENST00000586063.1
ENST00000270310.2
ENST00000588265.1
FXYD7


FXYD domain containing ion transport regulator 7


chr17_+_73472575 0.146 ENST00000375248.5
KIAA0195
KIAA0195
chr3_+_46923670 0.144 ENST00000427125.2
ENST00000430002.2
PTH1R

parathyroid hormone 1 receptor

chr17_+_1959369 0.143 ENST00000576444.1
ENST00000322941.3
HIC1

hypermethylated in cancer 1

chr14_-_106816253 0.143 ENST00000390615.2
IGHV3-33
immunoglobulin heavy variable 3-33
chr1_-_117210290 0.143 ENST00000369483.1
ENST00000369486.3
IGSF3

immunoglobulin superfamily, member 3

chrX_+_48644962 0.142 ENST00000376670.3
ENST00000376665.3
GATA1

GATA binding protein 1 (globin transcription factor 1)

chr12_-_49259643 0.142 ENST00000309739.5
RND1
Rho family GTPase 1
chr10_-_25012597 0.141 ENST00000396432.2
ARHGAP21
Rho GTPase activating protein 21
chr11_+_20044096 0.140 ENST00000533917.1
NAV2
neuron navigator 2
chr4_-_95264008 0.140 ENST00000295256.5
HPGDS
hematopoietic prostaglandin D synthase
chr7_-_137686791 0.139 ENST00000452463.1
ENST00000330387.6
ENST00000456390.1
CREB3L2


cAMP responsive element binding protein 3-like 2


chr11_+_20044600 0.137 ENST00000311043.8
NAV2
neuron navigator 2
chr11_+_75273246 0.134 ENST00000526397.1
ENST00000529643.1
ENST00000525492.1
ENST00000530284.1
ENST00000532356.1
ENST00000524558.1
SERPINH1





serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)





chr8_+_22409193 0.134 ENST00000240123.7
SORBS3
sorbin and SH3 domain containing 3
chr22_+_24309089 0.133 ENST00000215770.5
DDTL
D-dopachrome tautomerase-like
chr7_-_73133959 0.133 ENST00000395155.3
ENST00000395154.3
ENST00000222812.3
ENST00000395156.3
STX1A



syntaxin 1A (brain)



chr10_+_111985713 0.133 ENST00000239007.7
MXI1
MAX interactor 1, dimerization protein
chr9_-_134151915 0.133 ENST00000372271.3
FAM78A
family with sequence similarity 78, member A
chr14_-_106725723 0.132 ENST00000390609.2
IGHV3-23
immunoglobulin heavy variable 3-23
chr20_+_62496596 0.132 ENST00000369927.4
ENST00000346249.4
ENST00000348257.5
ENST00000352482.4
ENST00000351424.4
ENST00000217121.5
ENST00000358548.4
TPD52L2






tumor protein D52-like 2






chr3_-_185826286 0.132 ENST00000537818.1
ENST00000422039.1
ENST00000434744.1
ETV5


ets variant 5


chr3_-_52273098 0.131 ENST00000597542.1
ENST00000499914.2
ENST00000305533.5
TLR9
TWF2

toll-like receptor 9
twinfilin actin-binding protein 2

chr9_+_99691286 0.130 ENST00000372322.3
NUTM2G
NUT family member 2G
chr1_+_12290121 0.130 ENST00000358136.3
ENST00000356315.4
VPS13D

vacuolar protein sorting 13 homolog D (S. cerevisiae)

chr9_-_97090926 0.129 ENST00000335456.7
ENST00000253262.4
ENST00000341207.4
NUTM2F


NUT family member 2F


chr16_+_30662050 0.128 ENST00000568754.1
PRR14
proline rich 14
chr11_-_104893863 0.128 ENST00000260315.3
ENST00000526056.1
ENST00000531367.1
ENST00000456094.1
ENST00000444749.2
ENST00000393141.2
ENST00000418434.1
ENST00000393139.2
CASP5







caspase 5, apoptosis-related cysteine peptidase







chr5_+_176560742 0.127 ENST00000439151.2
NSD1
nuclear receptor binding SET domain protein 1
chr19_-_10628117 0.127 ENST00000333430.4
S1PR5
sphingosine-1-phosphate receptor 5
chr5_+_15500280 0.124 ENST00000504595.1
FBXL7
F-box and leucine-rich repeat protein 7
chr2_-_128785688 0.124 ENST00000259234.6
SAP130
Sin3A-associated protein, 130kDa
chr5_-_172198190 0.124 ENST00000239223.3
DUSP1
dual specificity phosphatase 1
chr1_-_1051455 0.123 ENST00000379339.1
ENST00000480643.1
ENST00000434641.1
ENST00000421241.2
C1orf159



chromosome 1 open reading frame 159



chr1_+_190448095 0.123 ENST00000424735.1
RP11-547I7.2
RP11-547I7.2
chr2_-_64371546 0.123 ENST00000358912.4
PELI1
pellino E3 ubiquitin protein ligase 1
chr20_-_35402123 0.122 ENST00000373740.3
ENST00000426836.1
ENST00000373745.3
ENST00000448110.2
ENST00000438549.1
ENST00000447406.1
ENST00000373750.4
ENST00000373734.4
DSN1







DSN1, MIS12 kinetochore complex component







chr19_+_50270219 0.122 ENST00000354293.5
ENST00000359032.5
AP2A1

adaptor-related protein complex 2, alpha 1 subunit

chr4_-_7873981 0.121 ENST00000360265.4
AFAP1
actin filament associated protein 1
chr16_+_71392616 0.120 ENST00000349553.5
ENST00000302628.4
ENST00000562305.1
CALB2


calbindin 2


chr17_-_73874654 0.120 ENST00000254816.2
TRIM47
tripartite motif containing 47
chr15_-_38856836 0.119 ENST00000450598.2
ENST00000559830.1
ENST00000558164.1
ENST00000310803.5
RASGRP1



RAS guanyl releasing protein 1 (calcium and DAG-regulated)



chr17_+_18280976 0.119 ENST00000399134.4
EVPLL
envoplakin-like
chr14_-_94595993 0.118 ENST00000238609.3
IFI27L2
interferon, alpha-inducible protein 27-like 2
chr15_+_63188009 0.118 ENST00000557900.1
RP11-1069G10.2
RP11-1069G10.2
chr1_+_243419306 0.117 ENST00000355875.4
ENST00000391846.1
ENST00000366541.3
ENST00000343783.6
SDCCAG8



serologically defined colon cancer antigen 8



chr16_+_33020496 0.117 ENST00000565407.2
IGHV3OR16-8
immunoglobulin heavy variable 3/OR16-8 (non-functional)
chr18_+_59854480 0.116 ENST00000256858.6
ENST00000398130.2
KIAA1468

KIAA1468

chr22_-_24316648 0.116 ENST00000403754.3
ENST00000430101.2
ENST00000398344.4
DDT


D-dopachrome tautomerase


chr11_+_75273101 0.116 ENST00000533603.1
ENST00000358171.3
ENST00000526242.1
SERPINH1


serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)


chr13_+_114321463 0.115 ENST00000335678.6
GRK1
G protein-coupled receptor kinase 1
chr17_-_79881408 0.114 ENST00000392366.3
MAFG
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G
chr9_-_44402427 0.114 ENST00000540551.1
BX088651.1
LOC100126582 protein; Uncharacterized protein
chr22_-_23922410 0.113 ENST00000249053.3
IGLL1
immunoglobulin lambda-like polypeptide 1
chr21_-_45681765 0.113 ENST00000431166.1
DNMT3L
DNA (cytosine-5-)-methyltransferase 3-like
chr10_+_112404132 0.112 ENST00000369519.3
RBM20
RNA binding motif protein 20
chr3_-_119379719 0.112 ENST00000493094.1
POPDC2
popeye domain containing 2
chr7_-_155604967 0.112 ENST00000297261.2
SHH
sonic hedgehog
chr2_+_42795839 0.111 ENST00000405094.1
MTA3
metastasis associated 1 family, member 3
chr17_+_7348374 0.110 ENST00000306071.2
ENST00000572857.1
CHRNB1

cholinergic receptor, nicotinic, beta 1 (muscle)

chr5_-_175461683 0.109 ENST00000514861.1
THOC3
THO complex 3
chr2_+_42795651 0.108 ENST00000407270.3
MTA3
metastasis associated 1 family, member 3
chr9_-_25678856 0.108 ENST00000358022.3
TUSC1
tumor suppressor candidate 1
chr16_+_30662184 0.107 ENST00000300835.4
PRR14
proline rich 14
chr19_+_13049413 0.106 ENST00000316448.5
ENST00000588454.1
CALR

calreticulin

chr19_-_40324255 0.105 ENST00000593685.1
ENST00000600611.1
DYRK1B

dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B

chr2_+_42795745 0.105 ENST00000406911.1
MTA3
metastasis associated 1 family, member 3
chr17_-_56494713 0.105 ENST00000407977.2
RNF43
ring finger protein 43
chr17_-_74023474 0.105 ENST00000301607.3
EVPL
envoplakin
chr17_-_74023291 0.104 ENST00000586740.1
EVPL
envoplakin
chr19_+_1752372 0.104 ENST00000382349.4
ONECUT3
one cut homeobox 3

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0000412 histone peptidyl-prolyl isomerization(GO:0000412)
0.2 0.7 GO:0071469 cellular response to alkaline pH(GO:0071469)
0.2 0.5 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.2 0.5 GO:1903570 regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572)
0.1 0.6 GO:0006218 uridine catabolic process(GO:0006218)
0.1 1.2 GO:0060753 regulation of mast cell chemotaxis(GO:0060753)
0.1 0.4 GO:0060474 positive regulation of sperm motility involved in capacitation(GO:0060474)
0.1 0.3 GO:0003099 positive regulation of the force of heart contraction by chemical signal(GO:0003099) regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.1 0.3 GO:0019085 early viral transcription(GO:0019085)
0.1 0.3 GO:1903966 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.1 0.2 GO:0048627 myoblast development(GO:0048627)
0.1 0.3 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.1 0.2 GO:2000157 regulation of protein K48-linked deubiquitination(GO:1903093) negative regulation of protein K48-linked deubiquitination(GO:1903094) negative regulation of ubiquitin-specific protease activity(GO:2000157)
0.1 1.1 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.1 0.4 GO:0051639 actin filament network formation(GO:0051639)
0.1 0.2 GO:0033123 positive regulation of cyclic nucleotide catabolic process(GO:0030807) positive regulation of cAMP catabolic process(GO:0030822) positive regulation of purine nucleotide catabolic process(GO:0033123)
0.1 0.2 GO:0002276 basophil activation involved in immune response(GO:0002276)
0.1 0.3 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.1 0.2 GO:0040010 positive regulation of growth rate(GO:0040010) regulation of gastric mucosal blood circulation(GO:1904344) positive regulation of gastric mucosal blood circulation(GO:1904346) gastric mucosal blood circulation(GO:1990768)
0.1 0.2 GO:0045608 negative regulation of auditory receptor cell differentiation(GO:0045608)
0.0 1.2 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.1 GO:0010725 regulation of primitive erythrocyte differentiation(GO:0010725) eosinophil fate commitment(GO:0035854)
0.0 0.2 GO:0042631 cellular response to water deprivation(GO:0042631)
0.0 0.2 GO:0003409 optic cup structural organization(GO:0003409)
0.0 0.2 GO:1902044 regulation of Fas signaling pathway(GO:1902044)
0.0 0.5 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 0.2 GO:0072268 pattern specification involved in metanephros development(GO:0072268)
0.0 0.3 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 0.2 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.0 0.2 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.0 0.1 GO:1900126 negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.0 0.3 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.0 0.3 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.0 0.1 GO:0072194 intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908) positive regulation of immature T cell proliferation in thymus(GO:0033092) right lung development(GO:0060458) primary prostatic bud elongation(GO:0060516) epithelial-mesenchymal signaling involved in prostate gland development(GO:0060738) kidney smooth muscle tissue development(GO:0072194) negative regulation of dopaminergic neuron differentiation(GO:1904339)
0.0 0.6 GO:2000291 regulation of myoblast proliferation(GO:2000291)
0.0 0.2 GO:0002378 immunoglobulin biosynthetic process(GO:0002378)
0.0 0.2 GO:0032661 regulation of interleukin-18 production(GO:0032661)
0.0 0.1 GO:1902523 positive regulation of protein K63-linked ubiquitination(GO:1902523)
0.0 0.2 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.0 0.3 GO:0021564 vagus nerve development(GO:0021564)
0.0 0.1 GO:0010701 positive regulation of norepinephrine secretion(GO:0010701) regulation of synaptic vesicle priming(GO:0010807)
0.0 0.3 GO:0016199 axon midline choice point recognition(GO:0016199)
0.0 0.2 GO:0014043 negative regulation of neuron maturation(GO:0014043)
0.0 0.8 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.2 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.0 0.1 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.0 0.0 GO:0048294 negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.0 0.1 GO:1900168 glial cell-derived neurotrophic factor secretion(GO:0044467) regulation of glial cell-derived neurotrophic factor secretion(GO:1900166) positive regulation of glial cell-derived neurotrophic factor secretion(GO:1900168)
0.0 0.1 GO:1902228 mammary gland fat development(GO:0060611) positive regulation of macrophage colony-stimulating factor signaling pathway(GO:1902228) positive regulation of response to macrophage colony-stimulating factor(GO:1903971) positive regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903974) positive regulation of microglial cell migration(GO:1904141)
0.0 0.1 GO:1903625 L-ascorbic acid biosynthetic process(GO:0019853) positive regulation of superoxide dismutase activity(GO:1901671) negative regulation of DNA catabolic process(GO:1903625) regulation of aminoacyl-tRNA ligase activity(GO:1903630) positive regulation of removal of superoxide radicals(GO:1904833)
0.0 0.1 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.0 0.2 GO:1903301 positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.0 0.1 GO:0007538 primary sex determination(GO:0007538)
0.0 0.1 GO:1903697 negative regulation of microvillus assembly(GO:1903697)
0.0 0.1 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 0.2 GO:1904352 positive regulation of protein catabolic process in the vacuole(GO:1904352)
0.0 0.1 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.0 0.1 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.0 0.1 GO:0051684 maintenance of Golgi location(GO:0051684)
0.0 0.1 GO:2001045 closure of optic fissure(GO:0061386) negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.0 0.2 GO:0000414 regulation of histone H3-K36 methylation(GO:0000414)
0.0 0.1 GO:0061537 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.0 0.1 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
0.0 0.2 GO:0035524 proline transmembrane transport(GO:0035524)
0.0 0.1 GO:0002818 intracellular defense response(GO:0002818)
0.0 0.3 GO:2000587 negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
0.0 0.1 GO:0032252 secretory granule localization(GO:0032252)
0.0 0.2 GO:0003433 chondrocyte development involved in endochondral bone morphogenesis(GO:0003433)
0.0 0.1 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037)
0.0 0.2 GO:0021999 neural plate anterior/posterior regionalization(GO:0021999)
0.0 0.1 GO:1990258 box C/D snoRNA 3'-end processing(GO:0000494) box C/D snoRNA metabolic process(GO:0033967) box C/D snoRNA processing(GO:0034963) histone glutamine methylation(GO:1990258)
0.0 0.2 GO:0051013 microtubule severing(GO:0051013)
0.0 0.1 GO:0072313 metanephric glomerular epithelium development(GO:0072244) metanephric glomerular visceral epithelial cell differentiation(GO:0072248) metanephric glomerular visceral epithelial cell development(GO:0072249) metanephric glomerular epithelial cell differentiation(GO:0072312) metanephric glomerular epithelial cell development(GO:0072313)
0.0 0.1 GO:0002925 positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.0 0.2 GO:0035095 behavioral response to nicotine(GO:0035095)
0.0 0.1 GO:0050653 chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
0.0 0.1 GO:0032808 lacrimal gland development(GO:0032808)
0.0 0.1 GO:0002501 peptide antigen assembly with MHC protein complex(GO:0002501)
0.0 0.3 GO:0071374 cellular response to parathyroid hormone stimulus(GO:0071374)
0.0 0.7 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 0.0 GO:1903595 positive regulation of histamine secretion by mast cell(GO:1903595)
0.0 0.1 GO:0010816 substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.0 0.1 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.0 0.1 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.0 0.2 GO:0015886 heme transport(GO:0015886)
0.0 0.1 GO:0099640 axo-dendritic protein transport(GO:0099640)
0.0 0.5 GO:0007176 regulation of epidermal growth factor-activated receptor activity(GO:0007176)
0.0 0.1 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.0 0.0 GO:0038178 complement component C5a signaling pathway(GO:0038178)
0.0 0.1 GO:0039506 modulation by virus of host molecular function(GO:0039506) suppression by virus of host molecular function(GO:0039507) suppression by virus of host catalytic activity(GO:0039513) modulation by virus of host catalytic activity(GO:0039516) suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process(GO:0039650) negative regulation by symbiont of host catalytic activity(GO:0052053) negative regulation by symbiont of host molecular function(GO:0052056) modulation by symbiont of host catalytic activity(GO:0052148)
0.0 0.1 GO:0045144 meiotic sister chromatid segregation(GO:0045144)
0.0 0.1 GO:0002326 B cell lineage commitment(GO:0002326) immunoglobulin V(D)J recombination(GO:0033152)
0.0 0.7 GO:0050919 negative chemotaxis(GO:0050919)
0.0 0.1 GO:0006642 triglyceride mobilization(GO:0006642)
0.0 0.2 GO:0034501 protein localization to kinetochore(GO:0034501)
0.0 0.1 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
0.0 0.1 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.1 GO:0010265 SCF complex assembly(GO:0010265)
0.0 0.1 GO:0050915 sensory perception of sour taste(GO:0050915)
0.0 0.1 GO:0072675 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.0 0.2 GO:0090168 Golgi reassembly(GO:0090168)
0.0 0.1 GO:0061198 fungiform papilla formation(GO:0061198)
0.0 0.0 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.0 0.2 GO:0002115 store-operated calcium entry(GO:0002115)
0.0 0.0 GO:1902309 negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.0 0.1 GO:0051140 regulation of NK T cell proliferation(GO:0051140) positive regulation of NK T cell proliferation(GO:0051142)
0.0 0.1 GO:2000330 interleukin-23-mediated signaling pathway(GO:0038155) positive regulation of T-helper 17 cell lineage commitment(GO:2000330)
0.0 0.1 GO:0086073 bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.0 0.0 GO:0018894 dibenzo-p-dioxin metabolic process(GO:0018894)
0.0 0.1 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.0 0.1 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.0 GO:0034729 histone H3-K79 methylation(GO:0034729)
0.0 0.3 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0 0.1 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.0 0.0 GO:0036496 regulation of translational initiation by eIF2 alpha dephosphorylation(GO:0036496)
0.0 0.1 GO:0071850 mitotic cell cycle arrest(GO:0071850)
0.0 0.1 GO:1902474 positive regulation of protein localization to synapse(GO:1902474)
0.0 0.2 GO:0006107 oxaloacetate metabolic process(GO:0006107)
0.0 0.0 GO:0002408 myeloid dendritic cell chemotaxis(GO:0002408)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:1990742 microvesicle(GO:1990742)
0.1 0.5 GO:0070435 Shc-EGFR complex(GO:0070435)
0.1 0.3 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.1 0.2 GO:0045160 myosin I complex(GO:0045160)
0.0 0.1 GO:0000939 nuclear MIS12/MIND complex(GO:0000818) condensed chromosome inner kinetochore(GO:0000939)
0.0 0.2 GO:0035838 growing cell tip(GO:0035838)
0.0 0.1 GO:0048787 presynaptic active zone membrane(GO:0048787) synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0 0.1 GO:0005608 laminin-3 complex(GO:0005608)
0.0 0.2 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.0 0.1 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.0 0.1 GO:0032002 interleukin-28 receptor complex(GO:0032002)
0.0 0.1 GO:0072558 NLRP1 inflammasome complex(GO:0072558)
0.0 1.2 GO:0045171 intercellular bridge(GO:0045171)
0.0 1.2 GO:0031941 filamentous actin(GO:0031941)
0.0 0.1 GO:0042022 interleukin-12 receptor complex(GO:0042022)
0.0 0.1 GO:0019815 B cell receptor complex(GO:0019815)
0.0 0.1 GO:0031302 intrinsic component of endosome membrane(GO:0031302)
0.0 0.2 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 0.1 GO:0032009 early phagosome(GO:0032009)
0.0 0.3 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 0.3 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.2 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.1 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.6 GO:0000791 euchromatin(GO:0000791)
0.0 0.1 GO:0042824 MHC class I peptide loading complex(GO:0042824)
0.0 1.1 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.0 0.1 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.0 0.1 GO:0005862 muscle thin filament tropomyosin(GO:0005862)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.2 0.5 GO:0033823 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823)
0.1 0.4 GO:0098782 mechanically-gated potassium channel activity(GO:0098782)
0.1 0.4 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.1 0.6 GO:0004850 uridine phosphorylase activity(GO:0004850)
0.1 0.8 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.1 0.5 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.1 0.5 GO:0048408 epidermal growth factor binding(GO:0048408)
0.1 0.7 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.1 0.9 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.1 0.2 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.1 0.2 GO:0036435 K48-linked polyubiquitin binding(GO:0036435)
0.1 0.5 GO:0015526 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.1 0.2 GO:0031768 ghrelin receptor binding(GO:0031768)
0.1 0.2 GO:0005298 proline:sodium symporter activity(GO:0005298)
0.1 0.4 GO:0036132 13-prostaglandin reductase activity(GO:0036132) 15-oxoprostaglandin 13-oxidase activity(GO:0047522)
0.1 0.3 GO:0031708 endothelin B receptor binding(GO:0031708)
0.1 0.3 GO:0016215 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.0 0.4 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.2 GO:0016499 orexin receptor activity(GO:0016499)
0.0 0.2 GO:0035651 AP-3 adaptor complex binding(GO:0035651)
0.0 0.2 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 0.1 GO:0045322 unmethylated CpG binding(GO:0045322)
0.0 0.1 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 0.1 GO:0050254 rhodopsin kinase activity(GO:0050254)
0.0 0.1 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.0 0.1 GO:0070644 vitamin D response element binding(GO:0070644)
0.0 0.2 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.7 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.1 GO:0033981 D-dopachrome decarboxylase activity(GO:0033981)
0.0 0.1 GO:0004991 parathyroid hormone receptor activity(GO:0004991)
0.0 1.0 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.1 GO:0052593 tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
0.0 0.3 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.1 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.1 GO:0008955 peptidoglycan glycosyltransferase activity(GO:0008955)
0.0 0.2 GO:0043426 MRF binding(GO:0043426)
0.0 0.7 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.2 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.2 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.3 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.2 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.0 GO:0070905 serine binding(GO:0070905)
0.0 0.1 GO:0016517 interleukin-12 receptor activity(GO:0016517)
0.0 0.1 GO:1990259 protein-glutamine N-methyltransferase activity(GO:0036009) histone-glutamine methyltransferase activity(GO:1990259)
0.0 0.4 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.1 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.0 0.1 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.2 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.1 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.0 0.1 GO:0005047 signal recognition particle binding(GO:0005047)
0.0 0.1 GO:0042806 fucose binding(GO:0042806)
0.0 0.1 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 0.2 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.0 0.1 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
0.0 0.0 GO:0004878 complement component C5a receptor activity(GO:0004878)
0.0 0.2 GO:0019215 intermediate filament binding(GO:0019215)
0.0 0.1 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.0 0.1 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.0 0.1 GO:0043237 laminin-1 binding(GO:0043237)
0.0 0.3 GO:0005024 transforming growth factor beta-activated receptor activity(GO:0005024)
0.0 0.1 GO:0019855 calcium channel inhibitor activity(GO:0019855) ATP-dependent protein binding(GO:0043008)
0.0 0.2 GO:0032052 bile acid binding(GO:0032052)
0.0 0.1 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.1 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.0 0.1 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.0 0.5 GO:0030371 translation repressor activity(GO:0030371)
0.0 0.2 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.2 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.2 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.0 0.1 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.0 0.3 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.1 GO:0004473 malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 PID_VEGF_VEGFR_PATHWAY VEGF and VEGFR signaling network
0.0 1.2 PID_IL8_CXCR2_PATHWAY IL8- and CXCR2-mediated signaling events
0.0 0.5 SA_TRKA_RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 0.5 PID_IL3_PATHWAY IL3-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 REACTOME_PYRIMIDINE_CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.7 REACTOME_SYNTHESIS_OF_PE Genes involved in Synthesis of PE
0.0 0.5 REACTOME_VEGF_LIGAND_RECEPTOR_INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 1.0 REACTOME_KINESINS Genes involved in Kinesins
0.0 0.8 REACTOME_CRMPS_IN_SEMA3A_SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.4 REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.5 REACTOME_SHC_MEDIATED_SIGNALLING Genes involved in SHC-mediated signalling
0.0 0.1 REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.3 REACTOME_REMOVAL_OF_THE_FLAP_INTERMEDIATE_FROM_THE_C_STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 1.1 REACTOME_RAP1_SIGNALLING Genes involved in Rap1 signalling
0.0 0.3 REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 1.2 REACTOME_GPVI_MEDIATED_ACTIVATION_CASCADE Genes involved in GPVI-mediated activation cascade
0.0 0.1 REACTOME_DESTABILIZATION_OF_MRNA_BY_AUF1_HNRNP_D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0 0.3 REACTOME_TETRAHYDROBIOPTERIN_BH4_SYNTHESIS_RECYCLING_SALVAGE_AND_REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 1.0 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.0 0.2 REACTOME_RECYCLING_OF_BILE_ACIDS_AND_SALTS Genes involved in Recycling of bile acids and salts
0.0 0.5 REACTOME_ACTIVATED_NOTCH1_TRANSMITS_SIGNAL_TO_THE_NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.4 REACTOME_BETA_DEFENSINS Genes involved in Beta defensins