Motif ID: EGR1_EGR4
Z-value: 0.998
Transcription factors associated with EGR1_EGR4:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
EGR1 | ENSG00000120738.7 | EGR1 |
EGR4 | ENSG00000135625.6 | EGR4 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
EGR1 | hg19_v2_chr5_+_137801160_137801179 | 0.76 | 1.5e-05 | Click! |
EGR4 | hg19_v2_chr2_-_73520667_73520833 | -0.11 | 6.0e-01 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.4 | 5.6 | GO:0046086 | adenosine biosynthetic process(GO:0046086) |
1.1 | 3.4 | GO:0002605 | negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581) negative regulation of dendritic cell antigen processing and presentation(GO:0002605) |
0.9 | 2.7 | GO:1903570 | regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572) |
0.9 | 2.7 | GO:0070634 | transepithelial ammonium transport(GO:0070634) |
0.8 | 2.3 | GO:0045210 | FasL biosynthetic process(GO:0045210) |
0.6 | 1.9 | GO:0072579 | molybdenum incorporation into molybdenum-molybdopterin complex(GO:0018315) metal incorporation into metallo-molybdopterin complex(GO:0042040) glycine receptor clustering(GO:0072579) |
0.6 | 5.1 | GO:0038028 | insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028) |
0.5 | 1.5 | GO:0019072 | viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074) |
0.5 | 1.4 | GO:1903926 | signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926) |
0.5 | 1.4 | GO:0090271 | positive regulation of fibroblast growth factor production(GO:0090271) |
0.5 | 1.4 | GO:0046947 | hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947) |
0.4 | 5.8 | GO:0060019 | radial glial cell differentiation(GO:0060019) |
0.4 | 3.5 | GO:0003065 | positive regulation of heart rate by epinephrine(GO:0003065) |
0.4 | 5.4 | GO:0033210 | leptin-mediated signaling pathway(GO:0033210) |
0.4 | 2.1 | GO:0014835 | myoblast differentiation involved in skeletal muscle regeneration(GO:0014835) |
0.4 | 1.2 | GO:0018894 | dibenzo-p-dioxin metabolic process(GO:0018894) |
0.4 | 8.7 | GO:0016540 | protein autoprocessing(GO:0016540) |
0.4 | 1.2 | GO:0045994 | positive regulation of translational initiation by iron(GO:0045994) |
0.4 | 1.1 | GO:0021849 | neuroblast division in subventricular zone(GO:0021849) |
0.4 | 2.5 | GO:0007386 | compartment pattern specification(GO:0007386) |
0.3 | 2.4 | GO:0021842 | directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842) |
0.3 | 2.7 | GO:0031914 | negative regulation of synaptic plasticity(GO:0031914) |
0.3 | 8.3 | GO:0033540 | fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540) |
0.3 | 1.0 | GO:0035674 | tricarboxylic acid transmembrane transport(GO:0035674) |
0.3 | 0.9 | GO:0060528 | secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528) |
0.3 | 4.9 | GO:0051639 | actin filament network formation(GO:0051639) |
0.3 | 0.9 | GO:0097187 | dentinogenesis(GO:0097187) |
0.3 | 0.9 | GO:0006597 | spermine biosynthetic process(GO:0006597) |
0.3 | 0.9 | GO:0052553 | induction by symbiont of host defense response(GO:0044416) induction of host immune response by virus(GO:0046730) active induction of host immune response by virus(GO:0046732) modulation by symbiont of host defense response(GO:0052031) induction by organism of defense response of other organism involved in symbiotic interaction(GO:0052251) modulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052255) positive regulation by symbiont of host defense response(GO:0052509) positive regulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052510) modulation by organism of immune response of other organism involved in symbiotic interaction(GO:0052552) modulation by symbiont of host immune response(GO:0052553) modulation by virus of host immune response(GO:0075528) |
0.3 | 0.9 | GO:0019417 | sulfur oxidation(GO:0019417) |
0.3 | 1.5 | GO:0007070 | negative regulation of transcription during mitosis(GO:0007068) negative regulation of transcription from RNA polymerase II promoter during mitosis(GO:0007070) |
0.3 | 1.2 | GO:0071484 | response to high light intensity(GO:0009644) cellular response to light intensity(GO:0071484) |
0.3 | 1.2 | GO:0031052 | mesodermal-endodermal cell signaling(GO:0003131) programmed DNA elimination(GO:0031049) chromosome breakage(GO:0031052) histone H2A-S139 phosphorylation(GO:0035978) positive regulation of cellular response to X-ray(GO:2000685) |
0.3 | 1.1 | GO:0003335 | corneocyte development(GO:0003335) |
0.3 | 1.4 | GO:1901503 | ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503) |
0.3 | 1.4 | GO:0048133 | germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728) |
0.3 | 1.1 | GO:0038195 | urokinase plasminogen activator signaling pathway(GO:0038195) |
0.3 | 1.1 | GO:0090038 | negative regulation of protein kinase C signaling(GO:0090038) |
0.3 | 1.3 | GO:0060054 | positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054) |
0.3 | 0.8 | GO:0045014 | carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014) |
0.2 | 1.0 | GO:1900533 | medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535) |
0.2 | 2.7 | GO:2000601 | positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601) |
0.2 | 1.0 | GO:2000230 | negative regulation of pancreatic stellate cell proliferation(GO:2000230) |
0.2 | 1.5 | GO:0016480 | negative regulation of transcription from RNA polymerase III promoter(GO:0016480) |
0.2 | 0.2 | GO:0014740 | negative regulation of muscle hyperplasia(GO:0014740) |
0.2 | 1.2 | GO:0006543 | glutamine catabolic process(GO:0006543) |
0.2 | 1.1 | GO:1904674 | positive regulation of somatic stem cell population maintenance(GO:1904674) |
0.2 | 1.3 | GO:0061502 | early endosome to recycling endosome transport(GO:0061502) |
0.2 | 0.7 | GO:0046900 | tetrahydrofolylpolyglutamate metabolic process(GO:0046900) |
0.2 | 1.5 | GO:0000389 | mRNA 3'-splice site recognition(GO:0000389) |
0.2 | 1.5 | GO:1900425 | negative regulation of defense response to bacterium(GO:1900425) |
0.2 | 3.1 | GO:0010739 | positive regulation of protein kinase A signaling(GO:0010739) |
0.2 | 0.6 | GO:0045226 | extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379) |
0.2 | 1.2 | GO:0010757 | negative regulation of plasminogen activation(GO:0010757) |
0.2 | 0.4 | GO:0061010 | gall bladder development(GO:0061010) |
0.2 | 1.0 | GO:1905232 | cellular response to L-glutamate(GO:1905232) |
0.2 | 0.6 | GO:0090187 | positive regulation of pancreatic juice secretion(GO:0090187) |
0.2 | 1.5 | GO:0022027 | interkinetic nuclear migration(GO:0022027) |
0.2 | 0.7 | GO:1900042 | positive regulation of interleukin-2 secretion(GO:1900042) |
0.2 | 0.5 | GO:0097069 | cellular response to thyroxine stimulus(GO:0097069) cellular response to L-phenylalanine derivative(GO:1904387) |
0.2 | 1.1 | GO:0045218 | zonula adherens maintenance(GO:0045218) |
0.2 | 0.9 | GO:0072103 | glomerulus vasculature morphogenesis(GO:0072103) glomerular capillary formation(GO:0072104) |
0.2 | 0.7 | GO:0070384 | Harderian gland development(GO:0070384) |
0.2 | 0.3 | GO:1903862 | positive regulation of oxidative phosphorylation(GO:1903862) |
0.2 | 1.4 | GO:0036486 | trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486) |
0.2 | 0.5 | GO:0048320 | commitment of multipotent stem cells to neuronal lineage in forebrain(GO:0021898) axial mesoderm formation(GO:0048320) |
0.2 | 0.7 | GO:0042418 | epinephrine biosynthetic process(GO:0042418) |
0.2 | 1.0 | GO:1903575 | cornified envelope assembly(GO:1903575) |
0.2 | 0.7 | GO:0072300 | positive regulation of metanephric glomerulus development(GO:0072300) |
0.2 | 0.6 | GO:0014022 | neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007) |
0.2 | 0.2 | GO:0045040 | outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040) establishment of protein localization to mitochondrial membrane(GO:0090151) |
0.2 | 0.5 | GO:0051685 | maintenance of ER location(GO:0051685) |
0.2 | 0.5 | GO:2001226 | negative regulation of chloride transport(GO:2001226) |
0.2 | 2.2 | GO:0038063 | collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) |
0.2 | 0.5 | GO:0006434 | seryl-tRNA aminoacylation(GO:0006434) |
0.1 | 0.9 | GO:0034436 | glycoprotein transport(GO:0034436) |
0.1 | 0.4 | GO:1904717 | excitatory chemical synaptic transmission(GO:0098976) regulation of AMPA glutamate receptor clustering(GO:1904717) positive regulation of AMPA glutamate receptor clustering(GO:1904719) |
0.1 | 0.4 | GO:0060979 | vasculogenesis involved in coronary vascular morphogenesis(GO:0060979) |
0.1 | 1.3 | GO:0006931 | substrate-dependent cell migration, cell attachment to substrate(GO:0006931) |
0.1 | 0.4 | GO:1903070 | negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070) |
0.1 | 0.6 | GO:0033634 | positive regulation of cell-cell adhesion mediated by integrin(GO:0033634) |
0.1 | 0.4 | GO:0021718 | superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722) |
0.1 | 0.7 | GO:0006438 | valyl-tRNA aminoacylation(GO:0006438) |
0.1 | 1.6 | GO:2000138 | positive regulation of cell proliferation involved in heart morphogenesis(GO:2000138) |
0.1 | 0.8 | GO:0006982 | response to lipid hydroperoxide(GO:0006982) |
0.1 | 0.7 | GO:0060684 | epithelial-mesenchymal cell signaling(GO:0060684) |
0.1 | 0.4 | GO:0070898 | RNA polymerase III transcriptional preinitiation complex assembly(GO:0070898) |
0.1 | 2.0 | GO:0090179 | planar cell polarity pathway involved in neural tube closure(GO:0090179) |
0.1 | 0.4 | GO:0045626 | negative regulation of T-helper 1 cell differentiation(GO:0045626) |
0.1 | 0.4 | GO:0035359 | negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359) |
0.1 | 0.7 | GO:1903553 | positive regulation of extracellular exosome assembly(GO:1903553) |
0.1 | 0.4 | GO:0036466 | synaptic vesicle recycling via endosome(GO:0036466) |
0.1 | 0.4 | GO:0097360 | chorionic trophoblast cell proliferation(GO:0097360) regulation of chorionic trophoblast cell proliferation(GO:1901382) |
0.1 | 1.7 | GO:0001542 | ovulation from ovarian follicle(GO:0001542) |
0.1 | 0.8 | GO:1902109 | negative regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902109) |
0.1 | 0.4 | GO:0038163 | thrombopoietin-mediated signaling pathway(GO:0038163) |
0.1 | 0.4 | GO:0003099 | positive regulation of the force of heart contraction by chemical signal(GO:0003099) regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585) |
0.1 | 0.8 | GO:0071321 | cellular response to cGMP(GO:0071321) |
0.1 | 0.5 | GO:1901895 | positive regulation of interferon-alpha biosynthetic process(GO:0045356) negative regulation of calcium-transporting ATPase activity(GO:1901895) |
0.1 | 0.5 | GO:0036302 | atrioventricular canal development(GO:0036302) |
0.1 | 3.4 | GO:0008053 | mitochondrial fusion(GO:0008053) |
0.1 | 0.5 | GO:1902460 | regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462) |
0.1 | 0.8 | GO:0030167 | proteoglycan catabolic process(GO:0030167) |
0.1 | 0.7 | GO:0070995 | NADPH oxidation(GO:0070995) |
0.1 | 1.2 | GO:0044387 | negative regulation of protein kinase activity by regulation of protein phosphorylation(GO:0044387) |
0.1 | 0.8 | GO:2000124 | regulation of endocannabinoid signaling pathway(GO:2000124) |
0.1 | 0.8 | GO:0018022 | peptidyl-lysine methylation(GO:0018022) |
0.1 | 0.7 | GO:0007185 | transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185) |
0.1 | 2.0 | GO:0051988 | regulation of attachment of spindle microtubules to kinetochore(GO:0051988) |
0.1 | 0.5 | GO:1905123 | regulation of endosome organization(GO:1904978) regulation of glucosylceramidase activity(GO:1905123) |
0.1 | 0.9 | GO:0035524 | proline transmembrane transport(GO:0035524) |
0.1 | 0.6 | GO:2000049 | positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049) |
0.1 | 0.1 | GO:1904580 | regulation of intracellular mRNA localization(GO:1904580) positive regulation of intracellular mRNA localization(GO:1904582) |
0.1 | 0.6 | GO:0018125 | peptidyl-cysteine methylation(GO:0018125) |
0.1 | 0.6 | GO:0006436 | tryptophanyl-tRNA aminoacylation(GO:0006436) |
0.1 | 1.0 | GO:0030174 | regulation of DNA-dependent DNA replication initiation(GO:0030174) |
0.1 | 0.3 | GO:1990569 | UDP-N-acetylglucosamine transport(GO:0015788) UDP-N-acetylglucosamine transmembrane transport(GO:1990569) |
0.1 | 1.4 | GO:0035372 | protein localization to microtubule(GO:0035372) |
0.1 | 0.5 | GO:1905098 | negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098) |
0.1 | 0.4 | GO:1903715 | regulation of aerobic respiration(GO:1903715) |
0.1 | 0.6 | GO:1903377 | negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377) |
0.1 | 0.6 | GO:1901908 | diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911) |
0.1 | 0.5 | GO:0061307 | cardiac neural crest cell differentiation involved in heart development(GO:0061307) cardiac neural crest cell development involved in heart development(GO:0061308) |
0.1 | 1.0 | GO:0032966 | negative regulation of collagen biosynthetic process(GO:0032966) |
0.1 | 0.2 | GO:2000646 | positive regulation of receptor catabolic process(GO:2000646) |
0.1 | 2.0 | GO:0060973 | cell migration involved in heart development(GO:0060973) |
0.1 | 1.6 | GO:0038003 | opioid receptor signaling pathway(GO:0038003) |
0.1 | 1.0 | GO:0000160 | phosphorelay signal transduction system(GO:0000160) |
0.1 | 0.3 | GO:0010286 | heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370) |
0.1 | 0.5 | GO:0000720 | pyrimidine dimer repair by nucleotide-excision repair(GO:0000720) |
0.1 | 0.8 | GO:1904627 | response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628) |
0.1 | 0.5 | GO:2000312 | regulation of kainate selective glutamate receptor activity(GO:2000312) |
0.1 | 0.2 | GO:1902965 | regulation of protein localization to early endosome(GO:1902965) positive regulation of protein localization to early endosome(GO:1902966) |
0.1 | 0.5 | GO:0032185 | septin cytoskeleton organization(GO:0032185) |
0.1 | 0.5 | GO:0031022 | nuclear migration along microfilament(GO:0031022) |
0.1 | 0.4 | GO:0045824 | negative regulation of innate immune response(GO:0045824) |
0.1 | 0.3 | GO:0060300 | regulation of cytokine activity(GO:0060300) |
0.1 | 0.6 | GO:0021979 | hypothalamus cell differentiation(GO:0021979) |
0.1 | 0.3 | GO:0007224 | smoothened signaling pathway(GO:0007224) |
0.1 | 0.3 | GO:1903644 | regulation of chaperone-mediated protein folding(GO:1903644) |
0.1 | 0.4 | GO:1901097 | negative regulation of autophagosome maturation(GO:1901097) |
0.1 | 0.2 | GO:0072137 | condensed mesenchymal cell proliferation(GO:0072137) |
0.1 | 1.1 | GO:0036066 | protein O-linked fucosylation(GO:0036066) |
0.1 | 0.2 | GO:0060978 | angiogenesis involved in coronary vascular morphogenesis(GO:0060978) |
0.1 | 0.2 | GO:0090370 | negative regulation of cholesterol efflux(GO:0090370) |
0.1 | 2.2 | GO:0002089 | lens morphogenesis in camera-type eye(GO:0002089) |
0.1 | 0.2 | GO:1901656 | glycoside transport(GO:1901656) |
0.1 | 0.5 | GO:0051798 | positive regulation of hair follicle development(GO:0051798) |
0.1 | 0.2 | GO:0048936 | peripheral nervous system neuron axonogenesis(GO:0048936) |
0.1 | 1.3 | GO:0010603 | regulation of cytoplasmic mRNA processing body assembly(GO:0010603) |
0.1 | 0.2 | GO:0021913 | regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913) |
0.1 | 0.2 | GO:0021793 | chemorepulsion of branchiomotor axon(GO:0021793) |
0.1 | 0.8 | GO:0019227 | neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870) |
0.1 | 0.6 | GO:0032926 | negative regulation of activin receptor signaling pathway(GO:0032926) |
0.1 | 0.1 | GO:0048382 | mesodermal cell migration(GO:0008078) forebrain dorsal/ventral pattern formation(GO:0021798) mesendoderm development(GO:0048382) |
0.1 | 0.3 | GO:0003383 | apical constriction(GO:0003383) |
0.1 | 0.6 | GO:0043654 | recognition of apoptotic cell(GO:0043654) |
0.1 | 0.2 | GO:0003358 | noradrenergic neuron development(GO:0003358) |
0.1 | 0.1 | GO:0007266 | Rho protein signal transduction(GO:0007266) |
0.1 | 0.5 | GO:0006452 | translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905) |
0.1 | 0.8 | GO:0034214 | protein hexamerization(GO:0034214) |
0.1 | 0.3 | GO:0060437 | negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387) lung growth(GO:0060437) |
0.1 | 0.4 | GO:1904293 | negative regulation of ERAD pathway(GO:1904293) |
0.1 | 1.3 | GO:0003376 | sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520) |
0.1 | 1.3 | GO:0000022 | mitotic spindle elongation(GO:0000022) |
0.1 | 0.3 | GO:0048845 | venous blood vessel morphogenesis(GO:0048845) |
0.1 | 0.4 | GO:0032483 | regulation of Rab protein signal transduction(GO:0032483) |
0.1 | 0.6 | GO:0070914 | UV-damage excision repair(GO:0070914) |
0.1 | 0.2 | GO:1902630 | regulation of membrane hyperpolarization(GO:1902630) |
0.1 | 0.2 | GO:0070407 | oxidation-dependent protein catabolic process(GO:0070407) |
0.1 | 0.4 | GO:0098528 | skeletal muscle fiber differentiation(GO:0098528) |
0.1 | 0.5 | GO:0050703 | interleukin-1 alpha secretion(GO:0050703) |
0.1 | 1.1 | GO:2000480 | negative regulation of cAMP-dependent protein kinase activity(GO:2000480) |
0.1 | 0.1 | GO:0090135 | actin filament branching(GO:0090135) |
0.1 | 0.3 | GO:0021543 | pallium development(GO:0021543) |
0.1 | 0.5 | GO:0002326 | B cell lineage commitment(GO:0002326) immunoglobulin V(D)J recombination(GO:0033152) |
0.1 | 0.7 | GO:0021859 | pyramidal neuron differentiation(GO:0021859) pyramidal neuron development(GO:0021860) |
0.1 | 0.4 | GO:0002175 | protein localization to paranode region of axon(GO:0002175) |
0.1 | 0.8 | GO:0031580 | membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580) |
0.1 | 0.3 | GO:0015015 | heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015) |
0.1 | 0.7 | GO:0050966 | detection of mechanical stimulus involved in sensory perception of pain(GO:0050966) |
0.1 | 0.3 | GO:0050916 | sensory perception of sweet taste(GO:0050916) |
0.1 | 0.3 | GO:0030421 | defecation(GO:0030421) |
0.1 | 0.2 | GO:0044314 | protein K27-linked ubiquitination(GO:0044314) |
0.1 | 0.7 | GO:1900028 | negative regulation of ruffle assembly(GO:1900028) |
0.1 | 0.2 | GO:0002337 | B-1a B cell differentiation(GO:0002337) |
0.1 | 0.6 | GO:0007135 | meiosis II(GO:0007135) |
0.1 | 1.2 | GO:0035020 | regulation of Rac protein signal transduction(GO:0035020) |
0.1 | 0.3 | GO:0034421 | post-translational protein acetylation(GO:0034421) |
0.1 | 0.3 | GO:0060052 | neurofilament cytoskeleton organization(GO:0060052) |
0.1 | 0.4 | GO:0034465 | response to carbon monoxide(GO:0034465) |
0.1 | 0.9 | GO:0040015 | negative regulation of multicellular organism growth(GO:0040015) |
0.1 | 0.5 | GO:0046940 | nucleoside monophosphate phosphorylation(GO:0046940) |
0.1 | 0.2 | GO:1900248 | cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248) |
0.1 | 0.2 | GO:0002572 | pro-T cell differentiation(GO:0002572) |
0.1 | 0.2 | GO:1903691 | positive regulation of wound healing, spreading of epidermal cells(GO:1903691) |
0.1 | 0.4 | GO:0016127 | cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127) |
0.1 | 0.2 | GO:0070295 | transformation of host cell by virus(GO:0019087) renal water absorption(GO:0070295) |
0.1 | 0.2 | GO:0060084 | synaptic transmission involved in micturition(GO:0060084) |
0.1 | 3.4 | GO:0008088 | axo-dendritic transport(GO:0008088) |
0.1 | 0.2 | GO:1901069 | guanosine-containing compound catabolic process(GO:1901069) |
0.1 | 0.9 | GO:0075522 | IRES-dependent viral translational initiation(GO:0075522) |
0.0 | 0.0 | GO:0060399 | positive regulation of growth hormone receptor signaling pathway(GO:0060399) |
0.0 | 0.6 | GO:0036120 | response to platelet-derived growth factor(GO:0036119) cellular response to platelet-derived growth factor stimulus(GO:0036120) |
0.0 | 0.4 | GO:0046604 | positive regulation of mitotic centrosome separation(GO:0046604) |
0.0 | 0.6 | GO:0014887 | muscle hypertrophy in response to stress(GO:0003299) cardiac muscle adaptation(GO:0014887) cardiac muscle hypertrophy in response to stress(GO:0014898) |
0.0 | 0.4 | GO:0032287 | peripheral nervous system myelin maintenance(GO:0032287) |
0.0 | 0.4 | GO:0035897 | proteolysis in other organism(GO:0035897) |
0.0 | 0.0 | GO:0007585 | respiratory gaseous exchange(GO:0007585) |
0.0 | 0.1 | GO:0030805 | regulation of cyclic nucleotide catabolic process(GO:0030805) regulation of cAMP catabolic process(GO:0030820) regulation of purine nucleotide catabolic process(GO:0033121) |
0.0 | 0.2 | GO:0090158 | endoplasmic reticulum membrane organization(GO:0090158) |
0.0 | 0.2 | GO:0060373 | regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373) |
0.0 | 1.1 | GO:0048934 | peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935) |
0.0 | 0.1 | GO:0009051 | pentose-phosphate shunt, oxidative branch(GO:0009051) |
0.0 | 6.6 | GO:1902600 | hydrogen ion transmembrane transport(GO:1902600) |
0.0 | 2.4 | GO:0050690 | regulation of defense response to virus by virus(GO:0050690) |
0.0 | 0.1 | GO:0070086 | ubiquitin-dependent endocytosis(GO:0070086) |
0.0 | 0.6 | GO:0010839 | negative regulation of keratinocyte proliferation(GO:0010839) |
0.0 | 0.0 | GO:0090178 | regulation of establishment of planar polarity involved in neural tube closure(GO:0090178) |
0.0 | 0.9 | GO:0045109 | intermediate filament organization(GO:0045109) |
0.0 | 0.3 | GO:0007212 | dopamine receptor signaling pathway(GO:0007212) |
0.0 | 0.3 | GO:1900239 | phenotypic switching(GO:0036166) regulation of phenotypic switching(GO:1900239) |
0.0 | 0.9 | GO:0034587 | piRNA metabolic process(GO:0034587) |
0.0 | 0.0 | GO:0002011 | morphogenesis of an epithelial sheet(GO:0002011) |
0.0 | 0.5 | GO:0050884 | neuromuscular process controlling posture(GO:0050884) |
0.0 | 0.2 | GO:1902162 | mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164) |
0.0 | 0.3 | GO:0051414 | response to cortisol(GO:0051414) |
0.0 | 0.3 | GO:0002024 | diet induced thermogenesis(GO:0002024) |
0.0 | 0.9 | GO:0005513 | detection of calcium ion(GO:0005513) |
0.0 | 0.5 | GO:0071313 | cellular response to caffeine(GO:0071313) |
0.0 | 0.2 | GO:0048013 | ephrin receptor signaling pathway(GO:0048013) |
0.0 | 0.5 | GO:0039536 | negative regulation of RIG-I signaling pathway(GO:0039536) |
0.0 | 0.4 | GO:0036010 | protein localization to endosome(GO:0036010) |
0.0 | 0.6 | GO:0033234 | negative regulation of protein sumoylation(GO:0033234) |
0.0 | 0.1 | GO:0043589 | skin morphogenesis(GO:0043589) |
0.0 | 0.2 | GO:0098501 | polynucleotide dephosphorylation(GO:0098501) |
0.0 | 0.2 | GO:2000504 | positive regulation of blood vessel remodeling(GO:2000504) |
0.0 | 1.2 | GO:0014733 | regulation of skeletal muscle adaptation(GO:0014733) |
0.0 | 0.5 | GO:0032025 | response to cobalt ion(GO:0032025) |
0.0 | 0.2 | GO:0033211 | adiponectin-activated signaling pathway(GO:0033211) |
0.0 | 1.2 | GO:0045589 | regulation of regulatory T cell differentiation(GO:0045589) |
0.0 | 0.4 | GO:1904263 | positive regulation of TORC1 signaling(GO:1904263) |
0.0 | 0.4 | GO:0061158 | 3'-UTR-mediated mRNA destabilization(GO:0061158) |
0.0 | 0.5 | GO:0018206 | peptidyl-methionine modification(GO:0018206) |
0.0 | 0.2 | GO:1903285 | negative regulation of synaptic transmission, dopaminergic(GO:0032227) negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470) |
0.0 | 1.9 | GO:0030212 | hyaluronan metabolic process(GO:0030212) |
0.0 | 0.4 | GO:0030951 | establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951) |
0.0 | 0.3 | GO:1902746 | regulation of lens fiber cell differentiation(GO:1902746) |
0.0 | 0.2 | GO:1903336 | negative regulation of vacuolar transport(GO:1903336) |
0.0 | 0.0 | GO:2000182 | regulation of progesterone biosynthetic process(GO:2000182) |
0.0 | 0.5 | GO:0035970 | peptidyl-threonine dephosphorylation(GO:0035970) |
0.0 | 0.6 | GO:0007076 | mitotic chromosome condensation(GO:0007076) |
0.0 | 0.9 | GO:1900273 | positive regulation of long-term synaptic potentiation(GO:1900273) |
0.0 | 0.4 | GO:1905245 | regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902959) positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902961) regulation of aspartic-type peptidase activity(GO:1905245) positive regulation of aspartic-type peptidase activity(GO:1905247) |
0.0 | 0.5 | GO:0032486 | Rap protein signal transduction(GO:0032486) |
0.0 | 0.2 | GO:0001992 | regulation of systemic arterial blood pressure by vasopressin(GO:0001992) |
0.0 | 0.3 | GO:0071850 | mitotic cell cycle arrest(GO:0071850) |
0.0 | 0.5 | GO:0099515 | vesicle transport along actin filament(GO:0030050) actin filament-based transport(GO:0099515) |
0.0 | 0.4 | GO:0043249 | erythrocyte maturation(GO:0043249) |
0.0 | 0.4 | GO:0045721 | negative regulation of gluconeogenesis(GO:0045721) |
0.0 | 0.2 | GO:0045600 | positive regulation of fat cell differentiation(GO:0045600) |
0.0 | 0.2 | GO:0006620 | SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616) posttranslational protein targeting to membrane(GO:0006620) |
0.0 | 0.3 | GO:0060318 | regulation of definitive erythrocyte differentiation(GO:0010724) definitive erythrocyte differentiation(GO:0060318) |
0.0 | 0.4 | GO:2000311 | regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311) |
0.0 | 0.6 | GO:0007252 | I-kappaB phosphorylation(GO:0007252) |
0.0 | 0.5 | GO:0000338 | protein deneddylation(GO:0000338) |
0.0 | 0.5 | GO:0060065 | uterus development(GO:0060065) |
0.0 | 0.1 | GO:1900107 | regulation of nodal signaling pathway(GO:1900107) |
0.0 | 0.1 | GO:0003415 | chondrocyte hypertrophy(GO:0003415) |
0.0 | 0.5 | GO:0042167 | porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149) |
0.0 | 0.4 | GO:0090394 | negative regulation of excitatory postsynaptic potential(GO:0090394) |
0.0 | 0.3 | GO:0070544 | histone H3-K36 demethylation(GO:0070544) |
0.0 | 0.3 | GO:0050747 | positive regulation of lipoprotein metabolic process(GO:0050747) |
0.0 | 0.6 | GO:0006853 | carnitine shuttle(GO:0006853) |
0.0 | 0.3 | GO:0030048 | actin filament-based movement(GO:0030048) |
0.0 | 0.3 | GO:0090344 | negative regulation of cell aging(GO:0090344) |
0.0 | 0.3 | GO:0035331 | negative regulation of hippo signaling(GO:0035331) |
0.0 | 0.1 | GO:1990258 | box C/D snoRNA 3'-end processing(GO:0000494) box C/D snoRNA metabolic process(GO:0033967) box C/D snoRNA processing(GO:0034963) histone glutamine methylation(GO:1990258) |
0.0 | 0.1 | GO:0015862 | uridine transport(GO:0015862) |
0.0 | 0.2 | GO:0006432 | phenylalanyl-tRNA aminoacylation(GO:0006432) |
0.0 | 0.2 | GO:0070307 | lens fiber cell development(GO:0070307) |
0.0 | 0.2 | GO:0097091 | synaptic vesicle clustering(GO:0097091) |
0.0 | 0.1 | GO:1904020 | regulation of G-protein coupled receptor internalization(GO:1904020) |
0.0 | 0.2 | GO:0007256 | activation of JNKK activity(GO:0007256) |
0.0 | 0.9 | GO:0010591 | regulation of lamellipodium assembly(GO:0010591) |
0.0 | 0.1 | GO:0035281 | pre-miRNA export from nucleus(GO:0035281) |
0.0 | 0.1 | GO:0018027 | peptidyl-lysine dimethylation(GO:0018027) |
0.0 | 0.6 | GO:0034199 | activation of protein kinase A activity(GO:0034199) |
0.0 | 0.2 | GO:0048539 | bone marrow development(GO:0048539) |
0.0 | 0.9 | GO:0090022 | regulation of neutrophil chemotaxis(GO:0090022) |
0.0 | 0.3 | GO:1903546 | protein localization to photoreceptor outer segment(GO:1903546) |
0.0 | 0.4 | GO:0003215 | cardiac right ventricle morphogenesis(GO:0003215) |
0.0 | 0.1 | GO:0021564 | vagus nerve development(GO:0021564) |
0.0 | 0.1 | GO:0042264 | peptidyl-aspartic acid modification(GO:0018197) peptidyl-aspartic acid hydroxylation(GO:0042264) |
0.0 | 0.7 | GO:0006646 | phosphatidylethanolamine biosynthetic process(GO:0006646) |
0.0 | 0.2 | GO:0097116 | postsynaptic density organization(GO:0097106) postsynaptic density assembly(GO:0097107) gephyrin clustering involved in postsynaptic density assembly(GO:0097116) neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118) |
0.0 | 0.3 | GO:0043487 | regulation of RNA stability(GO:0043487) |
0.0 | 0.1 | GO:0016476 | regulation of embryonic cell shape(GO:0016476) |
0.0 | 0.7 | GO:0043162 | ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162) |
0.0 | 0.3 | GO:2000507 | positive regulation of energy homeostasis(GO:2000507) |
0.0 | 0.1 | GO:0035964 | COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205) |
0.0 | 0.2 | GO:0031119 | tRNA pseudouridine synthesis(GO:0031119) |
0.0 | 0.2 | GO:0002315 | marginal zone B cell differentiation(GO:0002315) |
0.0 | 0.0 | GO:0001994 | norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001994) |
0.0 | 0.4 | GO:0023019 | signal transduction involved in regulation of gene expression(GO:0023019) |
0.0 | 0.2 | GO:0032962 | positive regulation of inositol trisphosphate biosynthetic process(GO:0032962) |
0.0 | 0.4 | GO:0010996 | response to auditory stimulus(GO:0010996) |
0.0 | 0.3 | GO:2000786 | positive regulation of autophagosome assembly(GO:2000786) |
0.0 | 0.2 | GO:0006621 | protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437) |
0.0 | 0.1 | GO:0072576 | hepatocyte proliferation(GO:0072574) epithelial cell proliferation involved in liver morphogenesis(GO:0072575) liver morphogenesis(GO:0072576) |
0.0 | 0.3 | GO:0002021 | response to dietary excess(GO:0002021) |
0.0 | 0.6 | GO:0060444 | branching involved in mammary gland duct morphogenesis(GO:0060444) |
0.0 | 0.1 | GO:0015798 | myo-inositol transport(GO:0015798) |
0.0 | 0.1 | GO:0036496 | regulation of translational initiation by eIF2 alpha dephosphorylation(GO:0036496) |
0.0 | 0.4 | GO:0001973 | adenosine receptor signaling pathway(GO:0001973) |
0.0 | 0.2 | GO:0046827 | positive regulation of protein export from nucleus(GO:0046827) |
0.0 | 0.5 | GO:0048268 | clathrin coat assembly(GO:0048268) |
0.0 | 0.2 | GO:1903593 | regulation of histamine secretion by mast cell(GO:1903593) |
0.0 | 0.4 | GO:0007100 | mitotic centrosome separation(GO:0007100) |
0.0 | 0.7 | GO:0032469 | endoplasmic reticulum calcium ion homeostasis(GO:0032469) |
0.0 | 0.2 | GO:0007517 | muscle organ development(GO:0007517) |
0.0 | 0.1 | GO:1904274 | tricellular tight junction assembly(GO:1904274) |
0.0 | 0.3 | GO:0090168 | Golgi reassembly(GO:0090168) |
0.0 | 0.1 | GO:0000973 | posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973) |
0.0 | 1.4 | GO:0038083 | peptidyl-tyrosine autophosphorylation(GO:0038083) |
0.0 | 0.6 | GO:0060334 | regulation of interferon-gamma-mediated signaling pathway(GO:0060334) |
0.0 | 0.1 | GO:2000643 | positive regulation of early endosome to late endosome transport(GO:2000643) |
0.0 | 0.4 | GO:0034975 | protein folding in endoplasmic reticulum(GO:0034975) |
0.0 | 2.2 | GO:0090630 | activation of GTPase activity(GO:0090630) |
0.0 | 1.0 | GO:0046579 | positive regulation of Ras protein signal transduction(GO:0046579) |
0.0 | 0.3 | GO:0007567 | parturition(GO:0007567) |
0.0 | 0.3 | GO:0006103 | 2-oxoglutarate metabolic process(GO:0006103) |
0.0 | 0.2 | GO:0051024 | positive regulation of immunoglobulin secretion(GO:0051024) |
0.0 | 0.2 | GO:0002903 | negative regulation of B cell apoptotic process(GO:0002903) positive regulation of phosphoprotein phosphatase activity(GO:0032516) |
0.0 | 0.3 | GO:0019371 | cyclooxygenase pathway(GO:0019371) |
0.0 | 0.2 | GO:0048280 | vesicle fusion with Golgi apparatus(GO:0048280) |
0.0 | 0.2 | GO:0060087 | relaxation of vascular smooth muscle(GO:0060087) |
0.0 | 0.1 | GO:0099500 | synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500) |
0.0 | 0.5 | GO:0043616 | keratinocyte proliferation(GO:0043616) |
0.0 | 0.5 | GO:0034453 | microtubule anchoring(GO:0034453) |
0.0 | 0.5 | GO:0072661 | protein targeting to plasma membrane(GO:0072661) |
0.0 | 0.3 | GO:0000185 | activation of MAPKKK activity(GO:0000185) |
0.0 | 0.4 | GO:0048286 | lung alveolus development(GO:0048286) |
0.0 | 1.0 | GO:0043268 | positive regulation of potassium ion transport(GO:0043268) |
0.0 | 0.8 | GO:0007566 | embryo implantation(GO:0007566) |
0.0 | 0.2 | GO:0000715 | nucleotide-excision repair, DNA damage recognition(GO:0000715) |
0.0 | 0.2 | GO:0050774 | negative regulation of dendrite morphogenesis(GO:0050774) |
0.0 | 0.1 | GO:0000414 | regulation of histone H3-K36 methylation(GO:0000414) |
0.0 | 0.1 | GO:0061051 | positive regulation of cell growth involved in cardiac muscle cell development(GO:0061051) |
0.0 | 0.6 | GO:0000289 | nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289) |
0.0 | 0.6 | GO:0048512 | circadian behavior(GO:0048512) |
0.0 | 0.1 | GO:0043248 | proteasome assembly(GO:0043248) |
0.0 | 0.4 | GO:0016486 | peptide hormone processing(GO:0016486) |
0.0 | 0.1 | GO:0060800 | regulation of cell differentiation involved in embryonic placenta development(GO:0060800) |
0.0 | 0.1 | GO:0042756 | drinking behavior(GO:0042756) |
0.0 | 0.2 | GO:0061179 | negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179) |
0.0 | 0.0 | GO:0060992 | response to fungicide(GO:0060992) |
0.0 | 0.7 | GO:0046580 | negative regulation of Ras protein signal transduction(GO:0046580) negative regulation of small GTPase mediated signal transduction(GO:0051058) |
0.0 | 0.2 | GO:0000212 | meiotic spindle organization(GO:0000212) |
0.0 | 0.1 | GO:0044351 | macropinocytosis(GO:0044351) |
0.0 | 0.3 | GO:0031290 | retinal ganglion cell axon guidance(GO:0031290) |
0.0 | 0.1 | GO:0006987 | activation of signaling protein activity involved in unfolded protein response(GO:0006987) |
0.0 | 0.1 | GO:0032020 | ISG15-protein conjugation(GO:0032020) |
0.0 | 0.1 | GO:0014051 | gamma-aminobutyric acid secretion(GO:0014051) |
0.0 | 0.5 | GO:0071480 | cellular response to gamma radiation(GO:0071480) |
0.0 | 0.4 | GO:0019221 | cytokine-mediated signaling pathway(GO:0019221) |
0.0 | 0.1 | GO:0034249 | negative regulation of translation(GO:0017148) negative regulation of cellular amide metabolic process(GO:0034249) |
0.0 | 0.4 | GO:0034314 | Arp2/3 complex-mediated actin nucleation(GO:0034314) |
0.0 | 0.1 | GO:0034334 | adherens junction maintenance(GO:0034334) |
0.0 | 0.3 | GO:0016180 | snRNA processing(GO:0016180) |
0.0 | 0.6 | GO:0043171 | peptide catabolic process(GO:0043171) |
0.0 | 0.2 | GO:0009886 | post-embryonic morphogenesis(GO:0009886) |
0.0 | 0.6 | GO:2000649 | regulation of sodium ion transmembrane transporter activity(GO:2000649) |
0.0 | 0.0 | GO:0042636 | negative regulation of hair cycle(GO:0042636) |
0.0 | 0.0 | GO:0002317 | plasma cell differentiation(GO:0002317) |
0.0 | 0.2 | GO:0019054 | modulation by virus of host process(GO:0019054) |
0.0 | 0.7 | GO:0006977 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977) signal transduction involved in mitotic G1 DNA damage checkpoint(GO:0072431) intracellular signal transduction involved in G1 DNA damage checkpoint(GO:1902400) |
0.0 | 0.2 | GO:0018026 | peptidyl-lysine monomethylation(GO:0018026) |
0.0 | 1.0 | GO:0006890 | retrograde vesicle-mediated transport, Golgi to ER(GO:0006890) |
0.0 | 0.1 | GO:0090503 | RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503) |
0.0 | 0.1 | GO:0001880 | Mullerian duct regression(GO:0001880) |
0.0 | 0.7 | GO:0030049 | muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275) |
0.0 | 0.1 | GO:0010940 | positive regulation of necrotic cell death(GO:0010940) |
0.0 | 0.2 | GO:0051085 | chaperone mediated protein folding requiring cofactor(GO:0051085) |
0.0 | 0.2 | GO:0000394 | RNA splicing, via endonucleolytic cleavage and ligation(GO:0000394) tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388) |
0.0 | 0.0 | GO:1900039 | positive regulation of cellular response to hypoxia(GO:1900039) |
0.0 | 0.2 | GO:0006490 | oligosaccharide-lipid intermediate biosynthetic process(GO:0006490) |
0.0 | 0.6 | GO:0036297 | interstrand cross-link repair(GO:0036297) |
0.0 | 0.1 | GO:0060732 | positive regulation of inositol phosphate biosynthetic process(GO:0060732) |
0.0 | 0.1 | GO:0090116 | C-5 methylation of cytosine(GO:0090116) |
0.0 | 0.3 | GO:0009226 | nucleotide-sugar biosynthetic process(GO:0009226) |
0.0 | 0.0 | GO:0000432 | regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432) positive regulation of transcription by glucose(GO:0046016) |
0.0 | 0.3 | GO:0032094 | response to food(GO:0032094) |
0.0 | 0.2 | GO:1904380 | endoplasmic reticulum mannose trimming(GO:1904380) |
0.0 | 0.1 | GO:0015937 | coenzyme A biosynthetic process(GO:0015937) |
0.0 | 0.1 | GO:0035518 | histone H2A monoubiquitination(GO:0035518) |
0.0 | 0.2 | GO:1901998 | toxin transport(GO:1901998) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.6 | 0.6 | GO:0000806 | Y chromosome(GO:0000806) |
0.5 | 8.3 | GO:0005751 | mitochondrial respiratory chain complex IV(GO:0005751) |
0.3 | 2.3 | GO:0030121 | AP-1 adaptor complex(GO:0030121) |
0.3 | 4.9 | GO:0035253 | ciliary rootlet(GO:0035253) |
0.3 | 2.2 | GO:0005587 | collagen type IV trimer(GO:0005587) |
0.3 | 3.4 | GO:0005577 | fibrinogen complex(GO:0005577) |
0.3 | 0.8 | GO:0098855 | HCN channel complex(GO:0098855) |
0.2 | 0.7 | GO:1990031 | pinceau fiber(GO:1990031) |
0.2 | 4.2 | GO:0005862 | muscle thin filament tropomyosin(GO:0005862) |
0.2 | 1.4 | GO:0070695 | FHF complex(GO:0070695) |
0.2 | 0.6 | GO:0097134 | cyclin E1-CDK2 complex(GO:0097134) |
0.2 | 2.8 | GO:0005916 | fascia adherens(GO:0005916) |
0.2 | 0.5 | GO:0017109 | glutamate-cysteine ligase complex(GO:0017109) |
0.2 | 2.2 | GO:0044327 | dendritic spine head(GO:0044327) |
0.2 | 2.6 | GO:0031209 | SCAR complex(GO:0031209) |
0.1 | 9.7 | GO:0005782 | peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907) |
0.1 | 0.9 | GO:0032311 | angiogenin-PRI complex(GO:0032311) |
0.1 | 1.2 | GO:0031232 | extrinsic component of external side of plasma membrane(GO:0031232) |
0.1 | 1.5 | GO:0016600 | flotillin complex(GO:0016600) |
0.1 | 0.4 | GO:0000126 | transcription factor TFIIIB complex(GO:0000126) |
0.1 | 0.5 | GO:0043293 | apoptosome(GO:0043293) |
0.1 | 1.1 | GO:0071546 | pi-body(GO:0071546) |
0.1 | 0.7 | GO:0034274 | Atg12-Atg5-Atg16 complex(GO:0034274) |
0.1 | 0.5 | GO:0098843 | postsynaptic endocytic zone(GO:0098843) |
0.1 | 0.8 | GO:0032437 | cuticular plate(GO:0032437) |
0.1 | 0.4 | GO:0016533 | cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533) |
0.1 | 1.3 | GO:0070938 | contractile ring(GO:0070938) |
0.1 | 1.1 | GO:0071438 | invadopodium membrane(GO:0071438) |
0.1 | 2.5 | GO:0001891 | phagocytic cup(GO:0001891) |
0.1 | 1.1 | GO:0005915 | zonula adherens(GO:0005915) |
0.1 | 0.2 | GO:0005827 | polar microtubule(GO:0005827) |
0.1 | 1.2 | GO:0035985 | senescence-associated heterochromatin focus(GO:0035985) |
0.1 | 1.2 | GO:0000812 | Swr1 complex(GO:0000812) |
0.1 | 0.6 | GO:0000110 | nucleotide-excision repair factor 1 complex(GO:0000110) |
0.1 | 0.5 | GO:0005797 | Golgi medial cisterna(GO:0005797) |
0.1 | 2.9 | GO:0030673 | axolemma(GO:0030673) |
0.1 | 0.2 | GO:1990124 | messenger ribonucleoprotein complex(GO:1990124) |
0.1 | 2.7 | GO:0035371 | microtubule plus-end(GO:0035371) |
0.1 | 1.1 | GO:0097431 | mitotic spindle pole(GO:0097431) |
0.1 | 1.1 | GO:0072546 | ER membrane protein complex(GO:0072546) |
0.1 | 0.2 | GO:0002945 | cyclin K-CDK13 complex(GO:0002945) |
0.1 | 1.5 | GO:0005885 | Arp2/3 protein complex(GO:0005885) |
0.1 | 0.4 | GO:0070381 | endosome to plasma membrane transport vesicle(GO:0070381) |
0.1 | 0.6 | GO:0042382 | paraspeckles(GO:0042382) |
0.1 | 1.0 | GO:0001673 | male germ cell nucleus(GO:0001673) |
0.1 | 7.1 | GO:0031093 | platelet alpha granule lumen(GO:0031093) |
0.1 | 0.2 | GO:0031417 | NatC complex(GO:0031417) |
0.1 | 0.2 | GO:0032937 | SREBP-SCAP-Insig complex(GO:0032937) |
0.1 | 0.5 | GO:0034993 | microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993) |
0.1 | 0.2 | GO:0016013 | syntrophin complex(GO:0016013) |
0.1 | 5.9 | GO:0005913 | cell-cell adherens junction(GO:0005913) |
0.1 | 0.6 | GO:0043240 | Fanconi anaemia nuclear complex(GO:0043240) |
0.1 | 1.2 | GO:0005952 | cAMP-dependent protein kinase complex(GO:0005952) |
0.1 | 2.1 | GO:0005640 | nuclear outer membrane(GO:0005640) |
0.1 | 0.2 | GO:0031256 | leading edge membrane(GO:0031256) |
0.1 | 0.3 | GO:0070436 | Grb2-EGFR complex(GO:0070436) |
0.1 | 0.9 | GO:0034709 | methylosome(GO:0034709) |
0.1 | 0.5 | GO:0098839 | postsynaptic density membrane(GO:0098839) |
0.0 | 0.5 | GO:0032009 | early phagosome(GO:0032009) |
0.0 | 1.1 | GO:0005614 | interstitial matrix(GO:0005614) |
0.0 | 0.2 | GO:0070044 | synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044) |
0.0 | 0.2 | GO:0031205 | endoplasmic reticulum Sec complex(GO:0031205) |
0.0 | 0.3 | GO:1990907 | beta-catenin-TCF complex(GO:1990907) |
0.0 | 0.7 | GO:0008385 | IkappaB kinase complex(GO:0008385) |
0.0 | 0.2 | GO:0009328 | phenylalanine-tRNA ligase complex(GO:0009328) |
0.0 | 0.5 | GO:0005642 | annulate lamellae(GO:0005642) |
0.0 | 0.5 | GO:0030877 | beta-catenin destruction complex(GO:0030877) |
0.0 | 0.5 | GO:0031616 | spindle pole centrosome(GO:0031616) |
0.0 | 0.5 | GO:0070652 | HAUS complex(GO:0070652) |
0.0 | 0.6 | GO:0031588 | nucleotide-activated protein kinase complex(GO:0031588) |
0.0 | 0.2 | GO:0016589 | NURF complex(GO:0016589) |
0.0 | 0.6 | GO:0031080 | nuclear pore outer ring(GO:0031080) |
0.0 | 0.9 | GO:0030867 | rough endoplasmic reticulum membrane(GO:0030867) |
0.0 | 0.2 | GO:0097443 | sorting endosome(GO:0097443) |
0.0 | 0.3 | GO:0005921 | gap junction(GO:0005921) |
0.0 | 0.2 | GO:0005956 | protein kinase CK2 complex(GO:0005956) |
0.0 | 0.8 | GO:0005922 | connexon complex(GO:0005922) |
0.0 | 0.4 | GO:0000109 | nucleotide-excision repair complex(GO:0000109) |
0.0 | 0.9 | GO:0030057 | desmosome(GO:0030057) |
0.0 | 0.6 | GO:0005652 | nuclear lamina(GO:0005652) |
0.0 | 0.3 | GO:0005641 | nuclear envelope lumen(GO:0005641) |
0.0 | 1.1 | GO:0005865 | striated muscle thin filament(GO:0005865) |
0.0 | 0.5 | GO:0043234 | protein complex(GO:0043234) |
0.0 | 0.4 | GO:0005883 | neurofilament(GO:0005883) |
0.0 | 0.4 | GO:0030123 | AP-3 adaptor complex(GO:0030123) |
0.0 | 0.7 | GO:0030014 | CCR4-NOT complex(GO:0030014) |
0.0 | 3.8 | GO:0030863 | cortical cytoskeleton(GO:0030863) |
0.0 | 1.3 | GO:0043034 | costamere(GO:0043034) |
0.0 | 0.5 | GO:0008250 | oligosaccharyltransferase complex(GO:0008250) |
0.0 | 0.4 | GO:0097539 | ciliary transition fiber(GO:0097539) |
0.0 | 0.7 | GO:0031235 | intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235) |
0.0 | 0.1 | GO:0042565 | RNA nuclear export complex(GO:0042565) |
0.0 | 0.3 | GO:0005744 | mitochondrial inner membrane presequence translocase complex(GO:0005744) |
0.0 | 2.4 | GO:0031463 | Cul3-RING ubiquitin ligase complex(GO:0031463) |
0.0 | 0.2 | GO:0002116 | semaphorin receptor complex(GO:0002116) |
0.0 | 0.8 | GO:0034361 | very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385) |
0.0 | 0.3 | GO:0032039 | integrator complex(GO:0032039) |
0.0 | 2.5 | GO:0060170 | ciliary membrane(GO:0060170) |
0.0 | 0.2 | GO:0005786 | signal recognition particle, endoplasmic reticulum targeting(GO:0005786) |
0.0 | 1.4 | GO:0070821 | tertiary granule membrane(GO:0070821) |
0.0 | 0.6 | GO:0071565 | nBAF complex(GO:0071565) |
0.0 | 0.4 | GO:0005905 | clathrin-coated pit(GO:0005905) |
0.0 | 0.1 | GO:0005602 | complement component C1 complex(GO:0005602) |
0.0 | 0.0 | GO:0002139 | stereocilia coupling link(GO:0002139) |
0.0 | 0.5 | GO:0031258 | lamellipodium membrane(GO:0031258) |
0.0 | 2.6 | GO:0008076 | voltage-gated potassium channel complex(GO:0008076) |
0.0 | 0.2 | GO:0036513 | Derlin-1 retrotranslocation complex(GO:0036513) |
0.0 | 0.3 | GO:0001741 | XY body(GO:0001741) |
0.0 | 0.3 | GO:0017119 | Golgi transport complex(GO:0017119) |
0.0 | 0.3 | GO:0042588 | zymogen granule(GO:0042588) |
0.0 | 0.2 | GO:0070022 | transforming growth factor beta receptor homodimeric complex(GO:0070022) |
0.0 | 0.2 | GO:0072669 | tRNA-splicing ligase complex(GO:0072669) |
0.0 | 0.5 | GO:0042629 | mast cell granule(GO:0042629) |
0.0 | 0.6 | GO:0031304 | intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305) |
0.0 | 0.2 | GO:0005955 | calcineurin complex(GO:0005955) |
0.0 | 0.2 | GO:0097440 | apical dendrite(GO:0097440) |
0.0 | 0.1 | GO:0031428 | box C/D snoRNP complex(GO:0031428) |
0.0 | 0.8 | GO:0005669 | transcription factor TFIID complex(GO:0005669) |
0.0 | 1.2 | GO:0043195 | terminal bouton(GO:0043195) |
0.0 | 4.0 | GO:0005938 | cell cortex(GO:0005938) |
0.0 | 0.2 | GO:0001518 | voltage-gated sodium channel complex(GO:0001518) |
0.0 | 0.6 | GO:0045171 | intercellular bridge(GO:0045171) |
0.0 | 1.7 | GO:0101003 | ficolin-1-rich granule membrane(GO:0101003) |
0.0 | 0.2 | GO:0034098 | VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098) |
0.0 | 0.1 | GO:0030897 | HOPS complex(GO:0030897) |
0.0 | 0.9 | GO:0033017 | sarcoplasmic reticulum membrane(GO:0033017) |
0.0 | 1.0 | GO:0005901 | caveola(GO:0005901) |
0.0 | 0.3 | GO:0016010 | dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665) |
0.0 | 0.9 | GO:0005811 | lipid particle(GO:0005811) |
0.0 | 0.8 | GO:0001725 | stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517) |
0.0 | 0.8 | GO:0034707 | chloride channel complex(GO:0034707) |
0.0 | 5.9 | GO:0043235 | receptor complex(GO:0043235) |
0.0 | 0.1 | GO:0071437 | invadopodium(GO:0071437) |
0.0 | 0.3 | GO:0016581 | NuRD complex(GO:0016581) CHD-type complex(GO:0090545) |
0.0 | 0.2 | GO:0031362 | anchored component of external side of plasma membrane(GO:0031362) |
0.0 | 0.1 | GO:0031201 | SNARE complex(GO:0031201) |
0.0 | 0.2 | GO:0098793 | presynapse(GO:0098793) |
0.0 | 0.3 | GO:0008074 | guanylate cyclase complex, soluble(GO:0008074) |
0.0 | 1.1 | GO:0030027 | lamellipodium(GO:0030027) |
0.0 | 0.6 | GO:0005884 | actin filament(GO:0005884) |
0.0 | 0.3 | GO:0014704 | intercalated disc(GO:0014704) |
0.0 | 1.3 | GO:0032580 | Golgi cisterna membrane(GO:0032580) |
0.0 | 0.6 | GO:0016328 | lateral plasma membrane(GO:0016328) |
0.0 | 0.2 | GO:0034451 | centriolar satellite(GO:0034451) |
0.0 | 0.0 | GO:0060199 | clathrin-sculpted glutamate transport vesicle(GO:0060199) clathrin-sculpted glutamate transport vesicle membrane(GO:0060203) |
0.0 | 0.2 | GO:0033180 | proton-transporting V-type ATPase, V1 domain(GO:0033180) |
0.0 | 0.3 | GO:0008180 | COP9 signalosome(GO:0008180) |
0.0 | 0.1 | GO:0005853 | eukaryotic translation elongation factor 1 complex(GO:0005853) |
0.0 | 0.1 | GO:0005964 | phosphorylase kinase complex(GO:0005964) |
0.0 | 0.2 | GO:0016327 | apicolateral plasma membrane(GO:0016327) |
0.0 | 0.2 | GO:0016281 | eukaryotic translation initiation factor 4F complex(GO:0016281) |
0.0 | 2.2 | GO:0016324 | apical plasma membrane(GO:0016324) |
0.0 | 0.6 | GO:0016234 | inclusion body(GO:0016234) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
2.1 | 8.2 | GO:0004165 | dodecenoyl-CoA delta-isomerase activity(GO:0004165) |
1.1 | 3.4 | GO:0070052 | collagen V binding(GO:0070052) |
0.6 | 1.9 | GO:0061599 | molybdopterin adenylyltransferase activity(GO:0061598) molybdopterin molybdotransferase activity(GO:0061599) |
0.5 | 1.9 | GO:0050211 | procollagen galactosyltransferase activity(GO:0050211) |
0.5 | 2.7 | GO:0043183 | vascular endothelial growth factor receptor 1 binding(GO:0043183) |
0.4 | 1.1 | GO:0030377 | urokinase plasminogen activator receptor activity(GO:0030377) |
0.3 | 0.9 | GO:0034189 | very-low-density lipoprotein particle binding(GO:0034189) |
0.3 | 0.9 | GO:0005298 | proline:sodium symporter activity(GO:0005298) |
0.3 | 1.2 | GO:0035501 | MH1 domain binding(GO:0035501) |
0.3 | 0.8 | GO:0098770 | FBXO family protein binding(GO:0098770) |
0.3 | 1.4 | GO:0070644 | vitamin D response element binding(GO:0070644) |
0.3 | 5.7 | GO:0008253 | 5'-nucleotidase activity(GO:0008253) |
0.3 | 1.3 | GO:0046624 | sphingolipid transporter activity(GO:0046624) |
0.2 | 1.2 | GO:0080019 | fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019) |
0.2 | 2.4 | GO:0005176 | ErbB-2 class receptor binding(GO:0005176) |
0.2 | 1.2 | GO:0070576 | vitamin D 24-hydroxylase activity(GO:0070576) |
0.2 | 8.0 | GO:0016676 | cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676) |
0.2 | 1.2 | GO:0004359 | glutaminase activity(GO:0004359) |
0.2 | 0.9 | GO:0034714 | type III transforming growth factor beta receptor binding(GO:0034714) |
0.2 | 0.7 | GO:0004603 | phenylethanolamine N-methyltransferase activity(GO:0004603) |
0.2 | 0.6 | GO:0047696 | beta-adrenergic receptor kinase activity(GO:0047696) |
0.2 | 0.6 | GO:0005137 | interleukin-5 receptor binding(GO:0005137) |
0.2 | 3.4 | GO:0008179 | adenylate cyclase binding(GO:0008179) |
0.2 | 0.6 | GO:1904288 | BAT3 complex binding(GO:1904288) |
0.2 | 0.8 | GO:0005222 | intracellular cAMP activated cation channel activity(GO:0005222) |
0.2 | 2.1 | GO:0051525 | NFAT protein binding(GO:0051525) |
0.2 | 0.5 | GO:0004357 | glutamate-cysteine ligase activity(GO:0004357) |
0.2 | 3.8 | GO:0051400 | BH domain binding(GO:0051400) |
0.2 | 0.8 | GO:1990050 | phosphatidic acid transporter activity(GO:1990050) |
0.2 | 0.5 | GO:0045322 | unmethylated CpG binding(GO:0045322) |
0.2 | 1.0 | GO:0015142 | citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142) |
0.2 | 0.9 | GO:0008269 | JAK pathway signal transduction adaptor activity(GO:0008269) |
0.2 | 1.5 | GO:0004075 | biotin carboxylase activity(GO:0004075) biotin binding(GO:0009374) |
0.2 | 6.5 | GO:0043539 | protein serine/threonine kinase activator activity(GO:0043539) |
0.2 | 0.6 | GO:0050501 | hyaluronan synthase activity(GO:0050501) |
0.2 | 0.5 | GO:0004828 | serine-tRNA ligase activity(GO:0004828) |
0.2 | 1.4 | GO:0045499 | chemorepellent activity(GO:0045499) |
0.1 | 0.4 | GO:0005173 | stem cell factor receptor binding(GO:0005173) |
0.1 | 0.4 | GO:0042799 | histone methyltransferase activity (H4-K20 specific)(GO:0042799) |
0.1 | 0.7 | GO:0004832 | valine-tRNA ligase activity(GO:0004832) |
0.1 | 3.8 | GO:0046965 | retinoid X receptor binding(GO:0046965) |
0.1 | 0.4 | GO:0001026 | TFIIIB-type transcription factor activity(GO:0001026) |
0.1 | 0.4 | GO:1904455 | ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455) |
0.1 | 0.4 | GO:0004913 | interleukin-4 receptor activity(GO:0004913) |
0.1 | 0.7 | GO:0004692 | cGMP-dependent protein kinase activity(GO:0004692) |
0.1 | 2.1 | GO:0043024 | ribosomal small subunit binding(GO:0043024) |
0.1 | 2.9 | GO:0017166 | vinculin binding(GO:0017166) |
0.1 | 1.6 | GO:0004985 | opioid receptor activity(GO:0004985) |
0.1 | 0.5 | GO:0004074 | biliverdin reductase activity(GO:0004074) |
0.1 | 0.7 | GO:0019776 | Atg8 ligase activity(GO:0019776) |
0.1 | 0.3 | GO:0010698 | acetyltransferase activator activity(GO:0010698) |
0.1 | 1.0 | GO:0004673 | phosphorelay sensor kinase activity(GO:0000155) protein histidine kinase activity(GO:0004673) |
0.1 | 0.1 | GO:0019957 | C-C chemokine binding(GO:0019957) |
0.1 | 0.6 | GO:0098519 | nucleotide phosphatase activity, acting on free nucleotides(GO:0098519) |
0.1 | 0.6 | GO:0004830 | tryptophan-tRNA ligase activity(GO:0004830) |
0.1 | 0.3 | GO:0005462 | UDP-N-acetylglucosamine transmembrane transporter activity(GO:0005462) |
0.1 | 0.4 | GO:0030171 | voltage-gated proton channel activity(GO:0030171) |
0.1 | 1.1 | GO:0005005 | transmembrane-ephrin receptor activity(GO:0005005) |
0.1 | 0.4 | GO:0004461 | lactose synthase activity(GO:0004461) |
0.1 | 0.6 | GO:0042610 | CD8 receptor binding(GO:0042610) |
0.1 | 0.6 | GO:0000298 | endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848) |
0.1 | 0.5 | GO:0055077 | gap junction hemi-channel activity(GO:0055077) |
0.1 | 0.5 | GO:0046899 | nucleoside triphosphate adenylate kinase activity(GO:0046899) |
0.1 | 1.2 | GO:0097493 | structural molecule activity conferring elasticity(GO:0097493) |
0.1 | 6.0 | GO:0004683 | calmodulin-dependent protein kinase activity(GO:0004683) |
0.1 | 1.0 | GO:0036042 | long-chain fatty acyl-CoA binding(GO:0036042) |
0.1 | 0.3 | GO:0017095 | heparan sulfate 6-O-sulfotransferase activity(GO:0017095) |
0.1 | 3.4 | GO:0030506 | ankyrin binding(GO:0030506) |
0.1 | 0.6 | GO:0051022 | GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022) |
0.1 | 0.3 | GO:0016309 | 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309) |
0.1 | 0.5 | GO:0042289 | MHC class II protein binding(GO:0042289) |
0.1 | 0.3 | GO:0000773 | phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101) |
0.1 | 0.9 | GO:0008428 | ribonuclease inhibitor activity(GO:0008428) |
0.1 | 0.4 | GO:0044729 | hemi-methylated DNA-binding(GO:0044729) |
0.1 | 0.7 | GO:0003988 | acetyl-CoA C-acyltransferase activity(GO:0003988) |
0.1 | 0.2 | GO:0017130 | poly(C) RNA binding(GO:0017130) |
0.1 | 0.3 | GO:0004706 | JUN kinase kinase kinase activity(GO:0004706) |
0.1 | 0.2 | GO:0001010 | transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010) |
0.1 | 2.2 | GO:0008093 | cytoskeletal adaptor activity(GO:0008093) |
0.1 | 1.3 | GO:0032036 | myosin heavy chain binding(GO:0032036) |
0.1 | 0.3 | GO:0050220 | prostaglandin-E synthase activity(GO:0050220) |
0.1 | 1.3 | GO:0030957 | Tat protein binding(GO:0030957) |
0.1 | 0.6 | GO:0004679 | AMP-activated protein kinase activity(GO:0004679) |
0.1 | 0.8 | GO:0008430 | selenium binding(GO:0008430) |
0.1 | 0.5 | GO:0004741 | [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741) |
0.1 | 0.5 | GO:0039552 | RIG-I binding(GO:0039552) |
0.1 | 0.4 | GO:0031708 | endothelin B receptor binding(GO:0031708) |
0.1 | 1.9 | GO:0070300 | phosphatidic acid binding(GO:0070300) |
0.1 | 0.5 | GO:0001537 | N-acetylgalactosamine 4-O-sulfotransferase activity(GO:0001537) |
0.1 | 1.3 | GO:0051959 | dynein light intermediate chain binding(GO:0051959) |
0.1 | 3.4 | GO:0001205 | transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205) |
0.1 | 0.5 | GO:1990599 | 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599) |
0.1 | 0.7 | GO:0004305 | ethanolamine kinase activity(GO:0004305) |
0.1 | 0.2 | GO:0070361 | mitochondrial light strand promoter anti-sense binding(GO:0070361) mitochondrial heavy strand promoter anti-sense binding(GO:0070362) mitochondrial heavy strand promoter sense binding(GO:0070364) |
0.1 | 0.3 | GO:0090554 | phosphatidylcholine-translocating ATPase activity(GO:0090554) |
0.1 | 0.4 | GO:0035473 | lipase binding(GO:0035473) |
0.1 | 0.4 | GO:0003953 | NAD+ nucleosidase activity(GO:0003953) |
0.1 | 0.2 | GO:0000026 | alpha-1,2-mannosyltransferase activity(GO:0000026) |
0.1 | 0.3 | GO:0042835 | BRE binding(GO:0042835) |
0.1 | 1.0 | GO:0070016 | armadillo repeat domain binding(GO:0070016) |
0.1 | 4.2 | GO:0008307 | structural constituent of muscle(GO:0008307) |
0.1 | 0.5 | GO:0046923 | ER retention sequence binding(GO:0046923) |
0.1 | 1.7 | GO:0015269 | calcium-activated potassium channel activity(GO:0015269) |
0.1 | 0.7 | GO:0017162 | aryl hydrocarbon receptor binding(GO:0017162) |
0.1 | 0.9 | GO:0016273 | arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274) |
0.1 | 0.2 | GO:0030292 | protein tyrosine kinase inhibitor activity(GO:0030292) hyaluronoglucuronidase activity(GO:0033906) |
0.1 | 0.8 | GO:0005243 | gap junction channel activity(GO:0005243) |
0.1 | 0.3 | GO:0004906 | interferon-gamma receptor activity(GO:0004906) |
0.0 | 0.8 | GO:0019911 | structural constituent of myelin sheath(GO:0019911) |
0.0 | 0.3 | GO:0005134 | interleukin-2 receptor binding(GO:0005134) |
0.0 | 0.2 | GO:0047888 | fatty acid peroxidase activity(GO:0047888) |
0.0 | 0.9 | GO:0008603 | cAMP-dependent protein kinase regulator activity(GO:0008603) |
0.0 | 0.9 | GO:0004708 | MAP kinase kinase activity(GO:0004708) |
0.0 | 0.8 | GO:0047372 | acylglycerol lipase activity(GO:0047372) |
0.0 | 1.8 | GO:0005520 | insulin-like growth factor binding(GO:0005520) |
0.0 | 6.8 | GO:0004896 | cytokine receptor activity(GO:0004896) |
0.0 | 0.2 | GO:0004176 | ATP-dependent peptidase activity(GO:0004176) |
0.0 | 3.0 | GO:0017112 | Rab guanyl-nucleotide exchange factor activity(GO:0017112) |
0.0 | 0.2 | GO:0004514 | nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514) |
0.0 | 0.9 | GO:0036041 | long-chain fatty acid binding(GO:0036041) |
0.0 | 0.7 | GO:0043522 | leucine zipper domain binding(GO:0043522) |
0.0 | 0.3 | GO:0004468 | lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468) |
0.0 | 0.3 | GO:0010997 | anaphase-promoting complex binding(GO:0010997) |
0.0 | 0.5 | GO:0048407 | platelet-derived growth factor binding(GO:0048407) |
0.0 | 1.0 | GO:0001968 | fibronectin binding(GO:0001968) |
0.0 | 1.7 | GO:0003785 | actin monomer binding(GO:0003785) |
0.0 | 2.4 | GO:0008138 | protein tyrosine/serine/threonine phosphatase activity(GO:0008138) |
0.0 | 0.4 | GO:0016312 | inositol bisphosphate phosphatase activity(GO:0016312) |
0.0 | 0.2 | GO:0005219 | ryanodine-sensitive calcium-release channel activity(GO:0005219) |
0.0 | 0.6 | GO:0022833 | mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833) |
0.0 | 0.8 | GO:0019992 | diacylglycerol binding(GO:0019992) |
0.0 | 0.8 | GO:0008331 | high voltage-gated calcium channel activity(GO:0008331) |
0.0 | 0.7 | GO:0071837 | HMG box domain binding(GO:0071837) |
0.0 | 0.9 | GO:0005092 | GDP-dissociation inhibitor activity(GO:0005092) |
0.0 | 0.5 | GO:0004579 | dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579) |
0.0 | 0.2 | GO:0060961 | phospholipase D inhibitor activity(GO:0060961) |
0.0 | 0.2 | GO:0005047 | signal recognition particle binding(GO:0005047) |
0.0 | 1.6 | GO:0016709 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709) |
0.0 | 0.5 | GO:0003836 | beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836) |
0.0 | 3.9 | GO:0005070 | SH3/SH2 adaptor activity(GO:0005070) |
0.0 | 4.3 | GO:0017048 | Rho GTPase binding(GO:0017048) |
0.0 | 0.4 | GO:0097109 | neuroligin family protein binding(GO:0097109) |
0.0 | 0.2 | GO:0043422 | protein kinase B binding(GO:0043422) |
0.0 | 0.2 | GO:0005000 | vasopressin receptor activity(GO:0005000) |
0.0 | 0.2 | GO:0005114 | type II transforming growth factor beta receptor binding(GO:0005114) |
0.0 | 0.6 | GO:0031489 | myosin V binding(GO:0031489) |
0.0 | 0.2 | GO:0048408 | epidermal growth factor binding(GO:0048408) |
0.0 | 0.7 | GO:0070006 | metalloaminopeptidase activity(GO:0070006) |
0.0 | 1.0 | GO:0017134 | fibroblast growth factor binding(GO:0017134) |
0.0 | 0.6 | GO:0004535 | poly(A)-specific ribonuclease activity(GO:0004535) |
0.0 | 0.2 | GO:0004862 | cAMP-dependent protein kinase inhibitor activity(GO:0004862) |
0.0 | 0.6 | GO:0008510 | sodium:bicarbonate symporter activity(GO:0008510) |
0.0 | 0.5 | GO:0004971 | AMPA glutamate receptor activity(GO:0004971) |
0.0 | 0.5 | GO:0001784 | phosphotyrosine binding(GO:0001784) |
0.0 | 9.1 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
0.0 | 0.2 | GO:0032051 | clathrin light chain binding(GO:0032051) |
0.0 | 0.2 | GO:0086006 | voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006) |
0.0 | 1.2 | GO:0004385 | guanylate kinase activity(GO:0004385) |
0.0 | 0.2 | GO:0070290 | N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290) |
0.0 | 0.8 | GO:0005247 | voltage-gated chloride channel activity(GO:0005247) |
0.0 | 0.1 | GO:0004594 | pantothenate kinase activity(GO:0004594) |
0.0 | 0.3 | GO:0051864 | histone demethylase activity (H3-K36 specific)(GO:0051864) |
0.0 | 0.2 | GO:0042301 | phosphate ion binding(GO:0042301) |
0.0 | 0.2 | GO:0035005 | 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005) |
0.0 | 0.1 | GO:1990259 | protein-glutamine N-methyltransferase activity(GO:0036009) histone-glutamine methyltransferase activity(GO:1990259) |
0.0 | 1.5 | GO:0001105 | RNA polymerase II transcription coactivator activity(GO:0001105) |
0.0 | 0.2 | GO:0004826 | phenylalanine-tRNA ligase activity(GO:0004826) |
0.0 | 0.1 | GO:0090631 | pre-miRNA transporter activity(GO:0090631) |
0.0 | 0.8 | GO:0005104 | fibroblast growth factor receptor binding(GO:0005104) |
0.0 | 3.3 | GO:0003777 | microtubule motor activity(GO:0003777) |
0.0 | 0.7 | GO:0008242 | omega peptidase activity(GO:0008242) |
0.0 | 0.2 | GO:0051011 | microtubule minus-end binding(GO:0051011) |
0.0 | 0.5 | GO:0043495 | protein anchor(GO:0043495) |
0.0 | 2.5 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
0.0 | 0.1 | GO:0030215 | semaphorin receptor binding(GO:0030215) |
0.0 | 0.2 | GO:0015277 | kainate selective glutamate receptor activity(GO:0015277) |
0.0 | 0.2 | GO:0036122 | BMP binding(GO:0036122) |
0.0 | 0.1 | GO:0004616 | phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616) |
0.0 | 0.5 | GO:0048018 | receptor agonist activity(GO:0048018) |
0.0 | 0.6 | GO:0050750 | low-density lipoprotein particle receptor binding(GO:0050750) |
0.0 | 0.1 | GO:0004991 | parathyroid hormone receptor activity(GO:0004991) |
0.0 | 0.8 | GO:0048027 | mRNA 5'-UTR binding(GO:0048027) |
0.0 | 0.6 | GO:0070403 | NAD+ binding(GO:0070403) |
0.0 | 1.1 | GO:0005154 | epidermal growth factor receptor binding(GO:0005154) |
0.0 | 0.7 | GO:0030159 | receptor signaling complex scaffold activity(GO:0030159) |
0.0 | 1.0 | GO:0051018 | protein kinase A binding(GO:0051018) |
0.0 | 0.4 | GO:0005536 | glucose binding(GO:0005536) |
0.0 | 0.3 | GO:0003924 | GTPase activity(GO:0003924) |
0.0 | 0.7 | GO:0015035 | protein disulfide oxidoreductase activity(GO:0015035) |
0.0 | 0.3 | GO:0030306 | ADP-ribosylation factor binding(GO:0030306) |
0.0 | 2.9 | GO:0008565 | protein transporter activity(GO:0008565) |
0.0 | 0.0 | GO:0001129 | RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly(GO:0001129) RNA polymerase II transcription factor activity, TBP-class protein binding(GO:0001132) |
0.0 | 0.3 | GO:0070700 | BMP receptor binding(GO:0070700) |
0.0 | 0.6 | GO:0004033 | aldo-keto reductase (NADP) activity(GO:0004033) |
0.0 | 0.3 | GO:0051219 | phosphoprotein binding(GO:0051219) |
0.0 | 0.4 | GO:0017070 | U6 snRNA binding(GO:0017070) |
0.0 | 0.8 | GO:0016538 | cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538) |
0.0 | 0.1 | GO:0004883 | glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051) |
0.0 | 0.2 | GO:0016863 | intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863) |
0.0 | 2.6 | GO:0005200 | structural constituent of cytoskeleton(GO:0005200) |
0.0 | 0.1 | GO:0042296 | ISG15 transferase activity(GO:0042296) |
0.0 | 0.0 | GO:0030297 | transmembrane receptor protein tyrosine kinase activator activity(GO:0030297) |
0.0 | 0.6 | GO:0016866 | intramolecular transferase activity(GO:0016866) |
0.0 | 0.5 | GO:0043014 | alpha-tubulin binding(GO:0043014) |
0.0 | 0.1 | GO:0097001 | ceramide binding(GO:0097001) |
0.0 | 0.9 | GO:0019003 | GDP binding(GO:0019003) |
0.0 | 0.2 | GO:0016175 | superoxide-generating NADPH oxidase activity(GO:0016175) |
0.0 | 0.0 | GO:0004937 | alpha1-adrenergic receptor activity(GO:0004937) |
0.0 | 0.6 | GO:0051721 | protein phosphatase 2A binding(GO:0051721) |
0.0 | 0.2 | GO:0008190 | eukaryotic initiation factor 4E binding(GO:0008190) |
0.0 | 0.2 | GO:0033192 | calmodulin-dependent protein phosphatase activity(GO:0033192) |
0.0 | 0.1 | GO:0071933 | Arp2/3 complex binding(GO:0071933) |
0.0 | 0.4 | GO:0005251 | delayed rectifier potassium channel activity(GO:0005251) |
0.0 | 0.2 | GO:0042974 | retinoic acid receptor binding(GO:0042974) |
0.0 | 0.0 | GO:0061752 | telomeric repeat-containing RNA binding(GO:0061752) |
0.0 | 0.6 | GO:0005035 | tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035) |
0.0 | 0.6 | GO:0030544 | Hsp70 protein binding(GO:0030544) |
0.0 | 0.7 | GO:0061631 | ubiquitin conjugating enzyme activity(GO:0061631) |
0.0 | 0.7 | GO:0050699 | WW domain binding(GO:0050699) |
0.0 | 0.1 | GO:0004565 | beta-galactosidase activity(GO:0004565) |
0.0 | 0.2 | GO:0008353 | RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353) |
0.0 | 1.0 | GO:0004004 | ATP-dependent RNA helicase activity(GO:0004004) |
0.0 | 0.4 | GO:0031072 | heat shock protein binding(GO:0031072) |
0.0 | 0.3 | GO:0030898 | actin-dependent ATPase activity(GO:0030898) |
0.0 | 0.3 | GO:0051010 | microtubule plus-end binding(GO:0051010) |
0.0 | 0.8 | GO:0019212 | phosphatase inhibitor activity(GO:0019212) |
0.0 | 0.2 | GO:0017154 | semaphorin receptor activity(GO:0017154) |
0.0 | 0.0 | GO:0086089 | voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089) |
0.0 | 0.3 | GO:0051879 | Hsp90 protein binding(GO:0051879) |
0.0 | 0.3 | GO:0097602 | cullin family protein binding(GO:0097602) |
0.0 | 0.1 | GO:0036310 | annealing helicase activity(GO:0036310) |
0.0 | 0.1 | GO:0050815 | phosphoserine binding(GO:0050815) |
0.0 | 0.1 | GO:0046974 | histone methyltransferase activity (H3-K9 specific)(GO:0046974) |
0.0 | 0.4 | GO:0097200 | cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200) |
0.0 | 0.1 | GO:0061133 | endopeptidase activator activity(GO:0061133) |
0.0 | 0.2 | GO:0031491 | nucleosome binding(GO:0031491) |
0.0 | 0.1 | GO:0008467 | [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467) |
0.0 | 0.2 | GO:0008349 | MAP kinase kinase kinase kinase activity(GO:0008349) |
0.0 | 0.2 | GO:0035259 | glucocorticoid receptor binding(GO:0035259) |
0.0 | 0.1 | GO:0015166 | polyol transmembrane transporter activity(GO:0015166) |
Gene overrepresentation in C2:CP category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.6 | 0.6 | NABA_BASEMENT_MEMBRANES | Genes encoding structural components of basement membranes |
0.2 | 6.6 | PID_GLYPICAN_1PATHWAY | Glypican 1 network |
0.2 | 10.8 | PID_ALPHA_SYNUCLEIN_PATHWAY | Alpha-synuclein signaling |
0.1 | 2.9 | PID_IL5_PATHWAY | IL5-mediated signaling events |
0.1 | 6.9 | PID_SYNDECAN_4_PATHWAY | Syndecan-4-mediated signaling events |
0.1 | 1.7 | PID_RETINOIC_ACID_PATHWAY | Retinoic acid receptors-mediated signaling |
0.1 | 2.0 | PID_NFKAPPAB_ATYPICAL_PATHWAY | Atypical NF-kappaB pathway |
0.1 | 1.2 | PID_ECADHERIN_KERATINOCYTE_PATHWAY | E-cadherin signaling in keratinocytes |
0.1 | 0.4 | PID_ERBB4_PATHWAY | ErbB4 signaling events |
0.1 | 4.6 | PID_RAS_PATHWAY | Regulation of Ras family activation |
0.1 | 3.7 | PID_RXR_VDR_PATHWAY | RXR and RAR heterodimerization with other nuclear receptor |
0.1 | 0.5 | ST_IL_13_PATHWAY | Interleukin 13 (IL-13) Pathway |
0.1 | 1.0 | SA_B_CELL_RECEPTOR_COMPLEXES | Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases. |
0.1 | 5.1 | PID_PTP1B_PATHWAY | Signaling events mediated by PTP1B |
0.1 | 5.1 | PID_AJDISS_2PATHWAY | Posttranslational regulation of adherens junction stability and dissassembly |
0.1 | 2.5 | ST_ERK1_ERK2_MAPK_PATHWAY | ERK1/ERK2 MAPK Pathway |
0.1 | 2.0 | PID_RET_PATHWAY | Signaling events regulated by Ret tyrosine kinase |
0.1 | 1.5 | PID_ERB_GENOMIC_PATHWAY | Validated nuclear estrogen receptor beta network |
0.1 | 1.6 | PID_PRL_SIGNALING_EVENTS_PATHWAY | Signaling events mediated by PRL |
0.1 | 1.8 | PID_BETA_CATENIN_DEG_PATHWAY | Degradation of beta catenin |
0.1 | 6.3 | PID_HIF1_TFPATHWAY | HIF-1-alpha transcription factor network |
0.1 | 0.2 | PID_ER_NONGENOMIC_PATHWAY | Plasma membrane estrogen receptor signaling |
0.1 | 2.0 | PID_UPA_UPAR_PATHWAY | Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling |
0.1 | 2.2 | PID_ECADHERIN_STABILIZATION_PATHWAY | Stabilization and expansion of the E-cadherin adherens junction |
0.1 | 1.6 | PID_WNT_SIGNALING_PATHWAY | Wnt signaling network |
0.1 | 2.2 | PID_FOXM1_PATHWAY | FOXM1 transcription factor network |
0.1 | 2.8 | PID_CDC42_REG_PATHWAY | Regulation of CDC42 activity |
0.0 | 1.1 | PID_EPHA_FWDPATHWAY | EPHA forward signaling |
0.0 | 4.3 | PID_LKB1_PATHWAY | LKB1 signaling events |
0.0 | 1.5 | SA_G1_AND_S_PHASES | Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition. |
0.0 | 3.1 | PID_RAC1_PATHWAY | RAC1 signaling pathway |
0.0 | 0.6 | PID_SYNDECAN_1_PATHWAY | Syndecan-1-mediated signaling events |
0.0 | 1.3 | PID_KIT_PATHWAY | Signaling events mediated by Stem cell factor receptor (c-Kit) |
0.0 | 2.5 | NABA_COLLAGENS | Genes encoding collagen proteins |
0.0 | 0.4 | PID_S1P_S1P4_PATHWAY | S1P4 pathway |
0.0 | 0.5 | PID_INSULIN_GLUCOSE_PATHWAY | Insulin-mediated glucose transport |
0.0 | 1.2 | PID_AURORA_A_PATHWAY | Aurora A signaling |
0.0 | 0.7 | PID_PI3KCI_AKT_PATHWAY | Class I PI3K signaling events mediated by Akt |
0.0 | 1.0 | PID_IL2_1PATHWAY | IL2-mediated signaling events |
0.0 | 0.5 | PID_P38_MK2_PATHWAY | p38 signaling mediated by MAPKAP kinases |
0.0 | 1.7 | PID_P53_REGULATION_PATHWAY | p53 pathway |
0.0 | 0.6 | PID_CIRCADIAN_PATHWAY | Circadian rhythm pathway |
0.0 | 0.9 | PID_INTEGRIN_A4B1_PATHWAY | Alpha4 beta1 integrin signaling events |
0.0 | 0.1 | SA_CASPASE_CASCADE | Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade. |
0.0 | 1.5 | PID_PLK1_PATHWAY | PLK1 signaling events |
0.0 | 0.5 | PID_P38_MKK3_6PATHWAY | p38 MAPK signaling pathway |
0.0 | 1.5 | PID_BCR_5PATHWAY | BCR signaling pathway |
0.0 | 0.1 | ST_ADRENERGIC | Adrenergic Pathway |
0.0 | 0.1 | PID_MAPK_TRK_PATHWAY | Trk receptor signaling mediated by the MAPK pathway |
0.0 | 0.4 | PID_NCADHERIN_PATHWAY | N-cadherin signaling events |
0.0 | 0.7 | PID_IL1_PATHWAY | IL1-mediated signaling events |
0.0 | 0.1 | PID_EPHA2_FWD_PATHWAY | EPHA2 forward signaling |
0.0 | 0.3 | PID_LPA4_PATHWAY | LPA4-mediated signaling events |
0.0 | 0.9 | PID_TGFBR_PATHWAY | TGF-beta receptor signaling |
0.0 | 1.1 | PID_CXCR4_PATHWAY | CXCR4-mediated signaling events |
0.0 | 0.1 | PID_ERBB1_RECEPTOR_PROXIMAL_PATHWAY | EGF receptor (ErbB1) signaling pathway |
0.0 | 4.2 | NABA_ECM_REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
0.0 | 0.4 | PID_BARD1_PATHWAY | BARD1 signaling events |
0.0 | 0.6 | SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES | Genes related to regulation of the actin cytoskeleton |
0.0 | 0.4 | PID_ATR_PATHWAY | ATR signaling pathway |
0.0 | 0.5 | PID_RAC1_REG_PATHWAY | Regulation of RAC1 activity |
0.0 | 0.5 | PID_ATM_PATHWAY | ATM pathway |
0.0 | 0.2 | PID_P38_ALPHA_BETA_PATHWAY | Regulation of p38-alpha and p38-beta |
0.0 | 1.0 | WNT_SIGNALING | Genes related to Wnt-mediated signal transduction |
Gene overrepresentation in C2:CP:REACTOME category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.3 | 5.2 | REACTOME_PYRIMIDINE_CATABOLISM | Genes involved in Pyrimidine catabolism |
0.2 | 4.9 | REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS | Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs) |
0.1 | 2.4 | REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION | Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression |
0.1 | 4.4 | REACTOME_NEPHRIN_INTERACTIONS | Genes involved in Nephrin interactions |
0.1 | 2.7 | REACTOME_VEGF_LIGAND_RECEPTOR_INTERACTIONS | Genes involved in VEGF ligand-receptor interactions |
0.1 | 0.2 | REACTOME_DSCAM_INTERACTIONS | Genes involved in DSCAM interactions |
0.1 | 4.4 | REACTOME_KINESINS | Genes involved in Kinesins |
0.1 | 1.2 | REACTOME_NEGATIVE_REGULATION_OF_THE_PI3K_AKT_NETWORK | Genes involved in Negative regulation of the PI3K/AKT network |
0.1 | 1.9 | REACTOME_DOWNREGULATION_OF_ERBB2_ERBB3_SIGNALING | Genes involved in Downregulation of ERBB2:ERBB3 signaling |
0.1 | 2.3 | REACTOME_P38MAPK_EVENTS | Genes involved in p38MAPK events |
0.1 | 2.3 | REACTOME_SPRY_REGULATION_OF_FGF_SIGNALING | Genes involved in Spry regulation of FGF signaling |
0.1 | 1.8 | REACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI | Genes involved in Pre-NOTCH Processing in Golgi |
0.1 | 2.9 | REACTOME_AMINE_COMPOUND_SLC_TRANSPORTERS | Genes involved in Amine compound SLC transporters |
0.1 | 1.6 | REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION | Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) |
0.1 | 1.4 | REACTOME_G2_M_DNA_DAMAGE_CHECKPOINT | Genes involved in G2/M DNA damage checkpoint |
0.1 | 1.2 | REACTOME_XENOBIOTICS | Genes involved in Xenobiotics |
0.1 | 4.2 | REACTOME_SMOOTH_MUSCLE_CONTRACTION | Genes involved in Smooth Muscle Contraction |
0.1 | 1.1 | REACTOME_RAS_ACTIVATION_UOPN_CA2_INFUX_THROUGH_NMDA_RECEPTOR | Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor |
0.1 | 0.6 | REACTOME_PROLACTIN_RECEPTOR_SIGNALING | Genes involved in Prolactin receptor signaling |
0.1 | 1.5 | REACTOME_SYNTHESIS_OF_PIPS_AT_THE_GOLGI_MEMBRANE | Genes involved in Synthesis of PIPs at the Golgi membrane |
0.1 | 1.1 | REACTOME_FGFR1_LIGAND_BINDING_AND_ACTIVATION | Genes involved in FGFR1 ligand binding and activation |
0.1 | 0.4 | REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_24_HYDROXYCHOLESTEROL | Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol |
0.1 | 0.7 | REACTOME_PECAM1_INTERACTIONS | Genes involved in PECAM1 interactions |
0.0 | 3.7 | REACTOME_COLLAGEN_FORMATION | Genes involved in Collagen formation |
0.0 | 0.8 | REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS | Genes involved in Role of DCC in regulating apoptosis |
0.0 | 0.2 | REACTOME_TRANSPORT_OF_RIBONUCLEOPROTEINS_INTO_THE_HOST_NUCLEUS | Genes involved in Transport of Ribonucleoproteins into the Host Nucleus |
0.0 | 0.4 | REACTOME_ADENYLATE_CYCLASE_INHIBITORY_PATHWAY | Genes involved in Adenylate cyclase inhibitory pathway |
0.0 | 0.9 | REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS | Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis |
0.0 | 1.1 | REACTOME_REGULATION_OF_AMPK_ACTIVITY_VIA_LKB1 | Genes involved in Regulation of AMPK activity via LKB1 |
0.0 | 1.9 | REACTOME_CGMP_EFFECTS | Genes involved in cGMP effects |
0.0 | 0.2 | REACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT | Genes involved in Regulation of beta-cell development |
0.0 | 1.2 | REACTOME_AMINO_ACID_SYNTHESIS_AND_INTERCONVERSION_TRANSAMINATION | Genes involved in Amino acid synthesis and interconversion (transamination) |
0.0 | 0.1 | REACTOME_NEP_NS2_INTERACTS_WITH_THE_CELLULAR_EXPORT_MACHINERY | Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery |
0.0 | 1.5 | REACTOME_PKA_MEDIATED_PHOSPHORYLATION_OF_CREB | Genes involved in PKA-mediated phosphorylation of CREB |
0.0 | 1.5 | REACTOME_PEROXISOMAL_LIPID_METABOLISM | Genes involved in Peroxisomal lipid metabolism |
0.0 | 1.4 | REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION | Genes involved in Cytosolic tRNA aminoacylation |
0.0 | 2.1 | REACTOME_GLUCONEOGENESIS | Genes involved in Gluconeogenesis |
0.0 | 0.5 | REACTOME_TRAFFICKING_AND_PROCESSING_OF_ENDOSOMAL_TLR | Genes involved in Trafficking and processing of endosomal TLR |
0.0 | 0.8 | REACTOME_GAP_JUNCTION_ASSEMBLY | Genes involved in Gap junction assembly |
0.0 | 0.8 | REACTOME_HYALURONAN_METABOLISM | Genes involved in Hyaluronan metabolism |
0.0 | 2.2 | REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS | Genes involved in Voltage gated Potassium channels |
0.0 | 1.1 | REACTOME_RAP1_SIGNALLING | Genes involved in Rap1 signalling |
0.0 | 0.6 | REACTOME_ACTIVATION_OF_RAC | Genes involved in Activation of Rac |
0.0 | 0.6 | REACTOME_TIE2_SIGNALING | Genes involved in Tie2 Signaling |
0.0 | 1.1 | REACTOME_GROWTH_HORMONE_RECEPTOR_SIGNALING | Genes involved in Growth hormone receptor signaling |
0.0 | 0.9 | REACTOME_FORMATION_OF_INCISION_COMPLEX_IN_GG_NER | Genes involved in Formation of incision complex in GG-NER |
0.0 | 0.8 | REACTOME_SIGNALING_BY_ERBB2 | Genes involved in Signaling by ERBB2 |
0.0 | 0.5 | REACTOME_UNBLOCKING_OF_NMDA_RECEPTOR_GLUTAMATE_BINDING_AND_ACTIVATION | Genes involved in Unblocking of NMDA receptor, glutamate binding and activation |
0.0 | 0.9 | REACTOME_CHOLESTEROL_BIOSYNTHESIS | Genes involved in Cholesterol biosynthesis |
0.0 | 0.5 | REACTOME_HOMOLOGOUS_RECOMBINATION_REPAIR_OF_REPLICATION_INDEPENDENT_DOUBLE_STRAND_BREAKS | Genes involved in Homologous recombination repair of replication-independent double-strand breaks |
0.0 | 0.7 | REACTOME_SYNTHESIS_OF_PE | Genes involved in Synthesis of PE |
0.0 | 0.6 | REACTOME_FANCONI_ANEMIA_PATHWAY | Genes involved in Fanconi Anemia pathway |
0.0 | 2.5 | REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY | Genes involved in Nuclear Receptor transcription pathway |
0.0 | 0.6 | REACTOME_CHYLOMICRON_MEDIATED_LIPID_TRANSPORT | Genes involved in Chylomicron-mediated lipid transport |
0.0 | 0.1 | REACTOME_GAB1_SIGNALOSOME | Genes involved in GAB1 signalosome |
0.0 | 0.6 | REACTOME_AMINE_DERIVED_HORMONES | Genes involved in Amine-derived hormones |
0.0 | 1.7 | REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES | Genes involved in Loss of Nlp from mitotic centrosomes |
0.0 | 0.7 | REACTOME_SIGNALING_BY_ROBO_RECEPTOR | Genes involved in Signaling by Robo receptor |
0.0 | 0.6 | REACTOME_G1_S_SPECIFIC_TRANSCRIPTION | Genes involved in G1/S-Specific Transcription |
0.0 | 0.3 | REACTOME_REGULATION_OF_IFNG_SIGNALING | Genes involved in Regulation of IFNG signaling |
0.0 | 0.4 | REACTOME_PROCESSING_OF_INTRONLESS_PRE_MRNAS | Genes involved in Processing of Intronless Pre-mRNAs |
0.0 | 0.2 | REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS | Genes involved in Ionotropic activity of Kainate Receptors |
0.0 | 1.4 | REACTOME_SIGNALING_BY_PDGF | Genes involved in Signaling by PDGF |
0.0 | 2.1 | REACTOME_G_ALPHA1213_SIGNALLING_EVENTS | Genes involved in G alpha (12/13) signalling events |
0.0 | 1.3 | REACTOME_METABOLISM_OF_NON_CODING_RNA | Genes involved in Metabolism of non-coding RNA |
0.0 | 1.5 | REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS | Genes involved in Metabolism of vitamins and cofactors |
0.0 | 0.8 | REACTOME_RNA_POL_II_TRANSCRIPTION_PRE_INITIATION_AND_PROMOTER_OPENING | Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening |
0.0 | 0.7 | REACTOME_G1_PHASE | Genes involved in G1 Phase |
0.0 | 0.5 | REACTOME_N_GLYCAN_ANTENNAE_ELONGATION_IN_THE_MEDIAL_TRANS_GOLGI | Genes involved in N-glycan antennae elongation in the medial/trans-Golgi |
0.0 | 0.7 | REACTOME_PTM_GAMMA_CARBOXYLATION_HYPUSINE_FORMATION_AND_ARYLSULFATASE_ACTIVATION | Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation |
0.0 | 0.2 | REACTOME_RECYCLING_PATHWAY_OF_L1 | Genes involved in Recycling pathway of L1 |
0.0 | 0.4 | REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION | Genes involved in Mitochondrial tRNA aminoacylation |
0.0 | 0.3 | REACTOME_CTNNB1_PHOSPHORYLATION_CASCADE | Genes involved in Beta-catenin phosphorylation cascade |
0.0 | 0.4 | REACTOME_SIGNALING_BY_SCF_KIT | Genes involved in Signaling by SCF-KIT |
0.0 | 0.1 | REACTOME_ERKS_ARE_INACTIVATED | Genes involved in ERKs are inactivated |
0.0 | 0.3 | REACTOME_KERATAN_SULFATE_BIOSYNTHESIS | Genes involved in Keratan sulfate biosynthesis |
0.0 | 0.0 | REACTOME_DESTABILIZATION_OF_MRNA_BY_KSRP | Genes involved in Destabilization of mRNA by KSRP |
0.0 | 0.4 | REACTOME_PLATELET_AGGREGATION_PLUG_FORMATION | Genes involved in Platelet Aggregation (Plug Formation) |
0.0 | 1.1 | REACTOME_APOPTOTIC_CLEAVAGE_OF_CELLULAR_PROTEINS | Genes involved in Apoptotic cleavage of cellular proteins |
0.0 | 0.2 | REACTOME_RECRUITMENT_OF_NUMA_TO_MITOTIC_CENTROSOMES | Genes involved in Recruitment of NuMA to mitotic centrosomes |
0.0 | 0.2 | REACTOME_CRMPS_IN_SEMA3A_SIGNALING | Genes involved in CRMPs in Sema3A signaling |
0.0 | 0.3 | REACTOME_SIGNAL_REGULATORY_PROTEIN_SIRP_FAMILY_INTERACTIONS | Genes involved in Signal regulatory protein (SIRP) family interactions |
0.0 | 0.5 | REACTOME_DEADENYLATION_OF_MRNA | Genes involved in Deadenylation of mRNA |
0.0 | 0.6 | REACTOME_SIGNAL_TRANSDUCTION_BY_L1 | Genes involved in Signal transduction by L1 |
0.0 | 1.0 | REACTOME_PROTEIN_FOLDING | Genes involved in Protein folding |
0.0 | 0.8 | REACTOME_INTERFERON_GAMMA_SIGNALING | Genes involved in Interferon gamma signaling |
0.0 | 0.5 | REACTOME_GLUCOSE_METABOLISM | Genes involved in Glucose metabolism |
0.0 | 0.2 | REACTOME_PRESYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS | Genes involved in Presynaptic nicotinic acetylcholine receptors |
0.0 | 0.7 | REACTOME_L1CAM_INTERACTIONS | Genes involved in L1CAM interactions |
0.0 | 0.2 | REACTOME_SYNTHESIS_SECRETION_AND_DEACYLATION_OF_GHRELIN | Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin |