Motif ID: EOMES

Z-value: 0.639


Transcription factors associated with EOMES:

Gene SymbolEntrez IDGene Name
EOMES ENSG00000163508.8 EOMES

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
EOMEShg19_v2_chr3_-_27763803_277638220.184.0e-01Click!


Activity profile for motif EOMES.

activity profile for motif EOMES


Sorted Z-values histogram for motif EOMES

Sorted Z-values for motif EOMES



Network of associatons between targets according to the STRING database.



First level regulatory network of EOMES

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_+_116937636 1.734 ENST00000368581.4
ENST00000229554.5
ENST00000368580.4
RSPH4A


radial spoke head 4 homolog A (Chlamydomonas)


chr22_-_50970506 1.333 ENST00000428989.2
ENST00000403326.1
ODF3B

outer dense fiber of sperm tails 3B

chr14_+_96858433 1.197 ENST00000267584.4
AK7
adenylate kinase 7
chr19_-_55677920 1.162 ENST00000524407.2
ENST00000526003.1
ENST00000534170.1
DNAAF3


dynein, axonemal, assembly factor 3


chr15_-_56757329 1.144 ENST00000260453.3
MNS1
meiosis-specific nuclear structural 1
chr7_+_6793740 1.043 ENST00000403107.1
ENST00000404077.1
ENST00000435395.1
ENST00000418406.1
RSPH10B2



radial spoke head 10 homolog B2 (Chlamydomonas)



chr7_-_6010263 1.022 ENST00000455618.2
ENST00000405415.1
ENST00000404406.1
ENST00000542644.1
RSPH10B



radial spoke head 10 homolog B (Chlamydomonas)



chr16_-_66959429 0.976 ENST00000420652.1
ENST00000299759.6
RRAD

Ras-related associated with diabetes

chr6_+_163148973 0.863 ENST00000366888.2
PACRG
PARK2 co-regulated
chr11_-_8615507 0.848 ENST00000431279.2
ENST00000418597.1
STK33

serine/threonine kinase 33

chr17_-_19266045 0.812 ENST00000395616.3
B9D1
B9 protein domain 1
chr3_-_113775328 0.760 ENST00000483766.1
ENST00000545063.1
ENST00000491000.1
ENST00000295878.3
KIAA1407



KIAA1407



chr7_+_94285637 0.733 ENST00000482108.1
ENST00000488574.1
PEG10

paternally expressed 10

chr7_+_89874524 0.683 ENST00000497910.1
C7orf63
chromosome 7 open reading frame 63
chr4_-_16085314 0.657 ENST00000510224.1
PROM1
prominin 1
chr7_+_89874483 0.651 ENST00000389297.4
ENST00000316089.8
C7orf63

chromosome 7 open reading frame 63

chr8_+_81397876 0.646 ENST00000430430.1
ZBTB10
zinc finger and BTB domain containing 10
chr4_-_16085340 0.634 ENST00000508167.1
PROM1
prominin 1
chrY_+_15016725 0.621 ENST00000336079.3
DDX3Y
DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
chr3_-_137834436 0.606 ENST00000327532.2
ENST00000467030.1
DZIP1L

DAZ interacting zinc finger protein 1-like

chr1_-_207095324 0.603 ENST00000530505.1
ENST00000367091.3
ENST00000442471.2
FAIM3


Fas apoptotic inhibitory molecule 3


chr5_+_75699149 0.585 ENST00000379730.3
IQGAP2
IQ motif containing GTPase activating protein 2
chr17_-_33775760 0.584 ENST00000534689.1
ENST00000532210.1
ENST00000526861.1
ENST00000531588.1
ENST00000285013.6
SLFN13




schlafen family member 13




chr3_-_127842612 0.554 ENST00000417360.1
ENST00000322623.5
RUVBL1

RuvB-like AAA ATPase 1

chr1_-_207095212 0.540 ENST00000420007.2
FAIM3
Fas apoptotic inhibitory molecule 3
chr17_-_19265982 0.531 ENST00000268841.6
ENST00000261499.4
ENST00000575478.1
B9D1


B9 protein domain 1


chr11_-_8615720 0.523 ENST00000358872.3
ENST00000454443.2
STK33

serine/threonine kinase 33

chr6_-_139613269 0.519 ENST00000358430.3
TXLNB
taxilin beta
chr22_-_37545972 0.515 ENST00000216223.5
IL2RB
interleukin 2 receptor, beta
chr2_-_229046361 0.513 ENST00000392056.3
SPHKAP
SPHK1 interactor, AKAP domain containing
chr2_-_229046330 0.513 ENST00000344657.5
SPHKAP
SPHK1 interactor, AKAP domain containing
chr11_-_8615488 0.494 ENST00000315204.1
ENST00000396672.1
ENST00000396673.1
STK33


serine/threonine kinase 33


chr5_+_156693159 0.483 ENST00000347377.6
CYFIP2
cytoplasmic FMR1 interacting protein 2
chr17_-_74533734 0.454 ENST00000589342.1
CYGB
cytoglobin
chr2_-_152118352 0.438 ENST00000331426.5
RBM43
RNA binding motif protein 43
chr11_-_70672645 0.435 ENST00000423696.2
SHANK2
SH3 and multiple ankyrin repeat domains 2
chr14_-_55658252 0.429 ENST00000395425.2
DLGAP5
discs, large (Drosophila) homolog-associated protein 5
chrX_+_51149767 0.421 ENST00000342995.2
CXorf67
chromosome X open reading frame 67
chr1_-_167906277 0.417 ENST00000271373.4
MPC2
mitochondrial pyruvate carrier 2
chrY_+_15016013 0.414 ENST00000360160.4
ENST00000454054.1
DDX3Y

DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked

chr7_+_102105370 0.407 ENST00000292616.5
LRWD1
leucine-rich repeats and WD repeat domain containing 1
chr2_+_230787201 0.406 ENST00000283946.3
FBXO36
F-box protein 36
chr2_+_230787213 0.394 ENST00000409992.1
FBXO36
F-box protein 36
chr1_+_213031570 0.393 ENST00000366971.4
FLVCR1
feline leukemia virus subgroup C cellular receptor 1
chr8_+_99076750 0.392 ENST00000545282.1
C8orf47
chromosome 8 open reading frame 47
chr1_-_115632035 0.387 ENST00000433172.1
ENST00000369514.2
ENST00000369516.2
ENST00000369515.2
TSPAN2



tetraspanin 2



chr14_+_56585048 0.382 ENST00000267460.4
PELI2
pellino E3 ubiquitin protein ligase family member 2
chr5_+_156693091 0.377 ENST00000318218.6
ENST00000442283.2
ENST00000522463.1
ENST00000521420.1
CYFIP2



cytoplasmic FMR1 interacting protein 2



chr11_+_65479462 0.369 ENST00000377046.3
ENST00000352980.4
ENST00000341318.4
KAT5


K(lysine) acetyltransferase 5


chr7_-_138482849 0.357 ENST00000353492.4
ATP6V0A4
ATPase, H+ transporting, lysosomal V0 subunit a4
chr1_-_203144941 0.357 ENST00000255416.4
MYBPH
myosin binding protein H
chr16_-_2031464 0.356 ENST00000356120.4
ENST00000354249.4
NOXO1

NADPH oxidase organizer 1

chr17_-_19265855 0.354 ENST00000440841.1
ENST00000395615.1
ENST00000461069.2
B9D1


B9 protein domain 1


chr14_-_21979428 0.350 ENST00000538267.1
ENST00000298717.4
METTL3

methyltransferase like 3

chr8_+_99076509 0.350 ENST00000318528.3
C8orf47
chromosome 8 open reading frame 47
chr11_-_105892937 0.348 ENST00000301919.4
ENST00000534458.1
ENST00000530108.1
ENST00000530788.1
MSANTD4



Myb/SANT-like DNA-binding domain containing 4 with coiled-coils



chr11_+_65479702 0.346 ENST00000530446.1
ENST00000534104.1
ENST00000530605.1
ENST00000528198.1
ENST00000531880.1
ENST00000534650.1
KAT5





K(lysine) acetyltransferase 5





chr4_+_186347388 0.339 ENST00000511138.1
ENST00000511581.1
C4orf47

chromosome 4 open reading frame 47

chr7_-_138482933 0.332 ENST00000310018.2
ATP6V0A4
ATPase, H+ transporting, lysosomal V0 subunit a4
chr1_+_65775204 0.331 ENST00000371069.4
DNAJC6
DnaJ (Hsp40) homolog, subfamily C, member 6
chr2_-_101767715 0.323 ENST00000376840.4
ENST00000409318.1
TBC1D8

TBC1 domain family, member 8 (with GRAM domain)

chr12_+_54378923 0.314 ENST00000303460.4
HOXC10
homeobox C10
chr7_+_106685079 0.314 ENST00000265717.4
PRKAR2B
protein kinase, cAMP-dependent, regulatory, type II, beta
chr9_+_100069933 0.309 ENST00000529487.1
CCDC180
coiled-coil domain containing 180
chr14_-_55658323 0.308 ENST00000554067.1
ENST00000247191.2
DLGAP5

discs, large (Drosophila) homolog-associated protein 5

chr17_+_68100989 0.298 ENST00000585558.1
ENST00000392670.1
KCNJ16

potassium inwardly-rectifying channel, subfamily J, member 16

chr17_+_67498538 0.294 ENST00000589647.1
MAP2K6
mitogen-activated protein kinase kinase 6
chr16_+_86544113 0.293 ENST00000262426.4
FOXF1
forkhead box F1
chr19_+_49496705 0.291 ENST00000595090.1
RUVBL2
RuvB-like AAA ATPase 2
chr7_-_37024665 0.288 ENST00000396040.2
ELMO1
engulfment and cell motility 1
chr17_-_42907564 0.287 ENST00000592524.1
GJC1
gap junction protein, gamma 1, 45kDa
chr14_-_54421190 0.285 ENST00000417573.1
BMP4
bone morphogenetic protein 4
chr8_-_79717750 0.279 ENST00000263851.4
ENST00000379113.2
IL7

interleukin 7

chr1_+_215256467 0.276 ENST00000391894.2
ENST00000444842.2
KCNK2

potassium channel, subfamily K, member 2

chr5_-_40755987 0.267 ENST00000337702.4
TTC33
tetratricopeptide repeat domain 33
chr21_+_33671264 0.265 ENST00000339944.4
MRAP
melanocortin 2 receptor accessory protein
chr20_-_39317868 0.263 ENST00000373313.2
MAFB
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
chr3_+_101504200 0.259 ENST00000422132.1
NXPE3
neurexophilin and PC-esterase domain family, member 3
chr14_+_24674926 0.257 ENST00000339917.5
ENST00000556621.1
ENST00000287913.6
ENST00000428351.2
ENST00000555092.1
TSSK4




testis-specific serine kinase 4




chr1_+_150229554 0.257 ENST00000369111.4
CA14
carbonic anhydrase XIV
chr14_-_64108125 0.257 ENST00000267522.3
WDR89
WD repeat domain 89
chr12_+_31812121 0.255 ENST00000395763.3
METTL20
methyltransferase like 20
chr1_-_43751230 0.254 ENST00000523677.1
C1orf210
chromosome 1 open reading frame 210
chr3_+_111805182 0.252 ENST00000430855.1
ENST00000431717.2
ENST00000264848.5
C3orf52


chromosome 3 open reading frame 52


chr8_-_27469196 0.246 ENST00000546343.1
ENST00000560566.1
CLU

clusterin

chr17_+_9066252 0.246 ENST00000436734.1
NTN1
netrin 1
chr19_+_49496782 0.246 ENST00000601968.1
ENST00000596837.1
RUVBL2

RuvB-like AAA ATPase 2

chr19_+_42349092 0.243 ENST00000269945.3
ENST00000596258.1
DMRTC2

DMRT-like family C2

chr17_+_58755184 0.243 ENST00000589222.1
ENST00000407086.3
ENST00000390652.5
BCAS3


breast carcinoma amplified sequence 3


chr3_+_125687987 0.239 ENST00000514116.1
ENST00000251776.4
ENST00000504401.1
ENST00000513830.1
ENST00000508088.1
ROPN1B




rhophilin associated tail protein 1B




chr11_-_8615687 0.238 ENST00000534493.1
ENST00000422559.2
STK33

serine/threonine kinase 33

chr6_+_154360616 0.236 ENST00000229768.5
ENST00000419506.2
ENST00000524163.1
ENST00000414028.2
ENST00000435918.2
ENST00000337049.4
OPRM1





opioid receptor, mu 1





chr1_-_167906020 0.227 ENST00000458574.1
MPC2
mitochondrial pyruvate carrier 2
chr17_-_41984835 0.221 ENST00000520406.1
ENST00000518478.1
ENST00000522172.1
ENST00000461854.1
ENST00000521178.1
ENST00000520305.1
ENST00000523501.1
ENST00000520241.1
MPP2







membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)







chr8_+_16884740 0.220 ENST00000318063.5
MICU3
mitochondrial calcium uptake family, member 3
chr7_-_100026280 0.219 ENST00000360951.4
ENST00000398027.2
ENST00000324725.6
ENST00000472716.1
ZCWPW1



zinc finger, CW type with PWWP domain 1



chr16_+_66914264 0.216 ENST00000311765.2
ENST00000568869.1
ENST00000561704.1
ENST00000568398.1
ENST00000566776.1
PDP2




pyruvate dehyrogenase phosphatase catalytic subunit 2




chr7_+_87505544 0.215 ENST00000265728.1
DBF4
DBF4 homolog (S. cerevisiae)
chr3_-_43147431 0.214 ENST00000441964.1
POMGNT2
protein O-linked mannose N-acetylglucosaminyltransferase 2 (beta 1,4-)
chr17_-_60005365 0.213 ENST00000444766.3
INTS2
integrator complex subunit 2
chr1_+_60280458 0.212 ENST00000455990.1
ENST00000371208.3
HOOK1

hook microtubule-tethering protein 1

chr17_+_37784749 0.209 ENST00000394265.1
ENST00000394267.2
PPP1R1B

protein phosphatase 1, regulatory (inhibitor) subunit 1B

chr2_-_148778323 0.208 ENST00000440042.1
ENST00000535373.1
ENST00000540442.1
ENST00000536575.1
ORC4



origin recognition complex, subunit 4



chr5_-_54468974 0.208 ENST00000381375.2
ENST00000296733.1
ENST00000322374.6
ENST00000334206.5
ENST00000331730.3
CDC20B




cell division cycle 20B




chr19_+_15121532 0.207 ENST00000292574.3
CCDC105
coiled-coil domain containing 105
chr17_-_62493131 0.207 ENST00000539111.2
POLG2
polymerase (DNA directed), gamma 2, accessory subunit
chr4_-_76862117 0.206 ENST00000507956.1
ENST00000507187.2
ENST00000399497.3
ENST00000286733.4
NAAA



N-acylethanolamine acid amidase



chr4_+_4291924 0.205 ENST00000355834.3
ENST00000337872.4
ENST00000538529.1
ENST00000502918.1
ZBTB49



zinc finger and BTB domain containing 49



chr8_+_96037205 0.204 ENST00000396124.4
NDUFAF6
NADH dehydrogenase (ubiquinone) complex I, assembly factor 6
chr12_-_101604185 0.203 ENST00000536262.2
SLC5A8
solute carrier family 5 (sodium/monocarboxylate cotransporter), member 8
chr19_-_36499521 0.201 ENST00000397428.3
ENST00000503121.1
ENST00000340477.5
ENST00000324444.3
ENST00000490730.1
SYNE4




spectrin repeat containing, nuclear envelope family member 4




chr19_+_38085731 0.201 ENST00000589117.1
ZNF540
zinc finger protein 540
chr10_-_61900762 0.200 ENST00000355288.2
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr14_+_96858454 0.200 ENST00000555570.1
AK7
adenylate kinase 7
chr12_+_121647962 0.199 ENST00000542067.1
P2RX4
purinergic receptor P2X, ligand-gated ion channel, 4
chr11_-_45928830 0.195 ENST00000449465.1
C11orf94
chromosome 11 open reading frame 94
chr7_-_91875358 0.193 ENST00000458177.1
ENST00000394507.1
ENST00000340022.2
ENST00000444960.1
KRIT1



KRIT1, ankyrin repeat containing



chr8_-_9760839 0.193 ENST00000519461.1
ENST00000517675.1
LINC00599

long intergenic non-protein coding RNA 599

chr6_-_131949200 0.192 ENST00000539158.1
ENST00000368058.1
MED23

mediator complex subunit 23

chr21_+_34619079 0.192 ENST00000433395.2
AP000295.9
AP000295.9
chr11_+_67183557 0.192 ENST00000445895.2
CARNS1
carnosine synthase 1
chr4_+_169418195 0.191 ENST00000261509.6
ENST00000335742.7
PALLD

palladin, cytoskeletal associated protein

chr1_-_226595741 0.191 ENST00000366794.5
ENST00000366792.1
ENST00000366791.5
PARP1


poly (ADP-ribose) polymerase 1


chr18_-_19284724 0.189 ENST00000580981.1
ENST00000289119.2
ABHD3

abhydrolase domain containing 3

chr5_+_149109825 0.188 ENST00000360453.4
ENST00000394320.3
ENST00000309241.5
PPARGC1B


peroxisome proliferator-activated receptor gamma, coactivator 1 beta


chr4_-_2420335 0.186 ENST00000503000.1
ZFYVE28
zinc finger, FYVE domain containing 28
chr14_+_76127529 0.186 ENST00000556977.1
ENST00000557636.1
ENST00000286650.5
ENST00000298832.9
TTLL5



tubulin tyrosine ligase-like family, member 5



chr13_+_113633620 0.186 ENST00000421756.1
ENST00000375601.3
MCF2L

MCF.2 cell line derived transforming sequence-like

chr1_+_15573757 0.185 ENST00000358897.4
ENST00000417793.1
ENST00000375999.3
ENST00000433640.2
FHAD1



forkhead-associated (FHA) phosphopeptide binding domain 1



chr2_-_161350305 0.184 ENST00000348849.3
RBMS1
RNA binding motif, single stranded interacting protein 1
chr17_-_38256973 0.181 ENST00000246672.3
NR1D1
nuclear receptor subfamily 1, group D, member 1
chr19_+_55795493 0.181 ENST00000309383.1
BRSK1
BR serine/threonine kinase 1
chr1_-_213031418 0.181 ENST00000356684.3
ENST00000426161.1
ENST00000424044.1
FLVCR1-AS1


FLVCR1 antisense RNA 1 (head to head)


chr4_-_151936865 0.180 ENST00000535741.1
LRBA
LPS-responsive vesicle trafficking, beach and anchor containing
chr8_+_67687413 0.177 ENST00000521960.1
ENST00000522398.1
ENST00000522629.1
ENST00000520976.1
ENST00000396596.1
SGK3




serum/glucocorticoid regulated kinase family, member 3




chr11_+_73498898 0.175 ENST00000535529.1
ENST00000497094.2
ENST00000411840.2
ENST00000535277.1
ENST00000398483.3
ENST00000542303.1
MRPL48





mitochondrial ribosomal protein L48





chr15_-_43622736 0.174 ENST00000544735.1
ENST00000567039.1
ENST00000305641.5
LCMT2


leucine carboxyl methyltransferase 2


chr9_-_136223324 0.174 ENST00000371974.3
SURF1
surfeit 1
chr11_+_1940925 0.173 ENST00000453458.1
ENST00000381557.2
ENST00000381589.3
ENST00000381579.3
ENST00000381563.4
ENST00000344578.4
TNNT3





troponin T type 3 (skeletal, fast)





chrX_-_134478012 0.172 ENST00000370766.3
ZNF75D
zinc finger protein 75D
chr7_+_16793160 0.172 ENST00000262067.4
TSPAN13
tetraspanin 13
chr17_-_74722536 0.171 ENST00000585429.1
JMJD6
jumonji domain containing 6
chr3_-_43147549 0.170 ENST00000344697.2
POMGNT2
protein O-linked mannose N-acetylglucosaminyltransferase 2 (beta 1,4-)
chr11_+_64808675 0.169 ENST00000529996.1
SAC3D1
SAC3 domain containing 1
chr18_+_48556470 0.169 ENST00000589076.1
ENST00000590061.1
ENST00000591914.1
ENST00000342988.3
SMAD4



SMAD family member 4



chr1_-_109203685 0.167 ENST00000402983.1
ENST00000420055.1
HENMT1

HEN1 methyltransferase homolog 1 (Arabidopsis)

chr11_+_537494 0.167 ENST00000270115.7
LRRC56
leucine rich repeat containing 56
chr2_+_45878790 0.166 ENST00000306156.3
PRKCE
protein kinase C, epsilon
chr10_-_13342097 0.165 ENST00000263038.4
PHYH
phytanoyl-CoA 2-hydroxylase
chrX_+_37430822 0.165 ENST00000378621.3
ENST00000378619.3
LANCL3

LanC lantibiotic synthetase component C-like 3 (bacterial)

chr14_-_51135036 0.164 ENST00000324679.4
SAV1
salvador homolog 1 (Drosophila)
chr22_+_29279552 0.164 ENST00000544604.2
ZNRF3
zinc and ring finger 3
chr1_-_36851475 0.163 ENST00000373129.3
STK40
serine/threonine kinase 40
chr5_-_94620239 0.163 ENST00000515393.1
MCTP1
multiple C2 domains, transmembrane 1
chr19_-_48867291 0.161 ENST00000435956.3
TMEM143
transmembrane protein 143
chr13_+_103459704 0.159 ENST00000602836.1
BIVM-ERCC5
BIVM-ERCC5 readthrough
chr2_-_148778258 0.159 ENST00000392857.5
ENST00000457954.1
ENST00000392858.1
ENST00000542387.1
ORC4



origin recognition complex, subunit 4



chr19_-_14016877 0.158 ENST00000454313.1
ENST00000591586.1
ENST00000346736.2
C19orf57


chromosome 19 open reading frame 57


chr19_+_7599597 0.157 ENST00000414982.3
ENST00000450331.3
PNPLA6

patatin-like phospholipase domain containing 6

chr12_-_42877726 0.156 ENST00000548696.1
PRICKLE1
prickle homolog 1 (Drosophila)
chr1_+_162531294 0.155 ENST00000367926.4
ENST00000271469.3
UAP1

UDP-N-acteylglucosamine pyrophosphorylase 1

chr1_+_246729724 0.155 ENST00000366513.4
ENST00000366512.3
CNST

consortin, connexin sorting protein

chr11_-_3663502 0.155 ENST00000359918.4
ART5
ADP-ribosyltransferase 5
chr13_+_113548643 0.155 ENST00000375608.3
MCF2L
MCF.2 cell line derived transforming sequence-like
chr12_-_42877764 0.152 ENST00000455697.1
PRICKLE1
prickle homolog 1 (Drosophila)
chr1_-_109203648 0.151 ENST00000370031.1
HENMT1
HEN1 methyltransferase homolog 1 (Arabidopsis)
chr22_+_45680822 0.151 ENST00000216211.4
ENST00000396082.2
UPK3A

uroplakin 3A

chr10_+_103986085 0.149 ENST00000370005.3
ELOVL3
ELOVL fatty acid elongase 3
chr19_-_48867171 0.147 ENST00000377431.2
ENST00000436660.2
ENST00000541566.1
TMEM143


transmembrane protein 143


chr6_+_79577189 0.147 ENST00000369940.2
IRAK1BP1
interleukin-1 receptor-associated kinase 1 binding protein 1
chr1_-_109203997 0.146 ENST00000370032.5
HENMT1
HEN1 methyltransferase homolog 1 (Arabidopsis)
chr3_-_52868931 0.145 ENST00000486659.1
MUSTN1
musculoskeletal, embryonic nuclear protein 1
chr17_-_57184260 0.145 ENST00000376149.3
ENST00000393066.3
TRIM37

tripartite motif containing 37

chr17_+_61851504 0.143 ENST00000359353.5
ENST00000389924.2
DDX42

DEAD (Asp-Glu-Ala-Asp) box helicase 42

chr8_-_18666360 0.142 ENST00000286485.8
PSD3
pleckstrin and Sec7 domain containing 3
chr20_-_17539456 0.141 ENST00000544874.1
ENST00000377868.2
BFSP1

beaded filament structural protein 1, filensin

chr1_+_15256230 0.141 ENST00000376028.4
ENST00000400798.2
KAZN

kazrin, periplakin interacting protein

chr17_-_17109579 0.140 ENST00000321560.3
PLD6
phospholipase D family, member 6
chr19_-_38085633 0.140 ENST00000593133.1
ENST00000590751.1
ENST00000358744.3
ENST00000328550.2
ENST00000451802.2
ZNF571




zinc finger protein 571




chr5_-_443239 0.139 ENST00000408966.2
C5orf55
chromosome 5 open reading frame 55
chr1_+_25598989 0.138 ENST00000454452.2
RHD
Rh blood group, D antigen
chr7_+_150020329 0.138 ENST00000323078.7
LRRC61
leucine rich repeat containing 61
chr10_+_26727333 0.136 ENST00000356785.4
APBB1IP
amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
chr5_+_61708582 0.136 ENST00000325324.6
IPO11
importin 11
chr1_+_162760513 0.136 ENST00000367915.1
ENST00000367917.3
ENST00000254521.3
ENST00000367913.1
HSD17B7



hydroxysteroid (17-beta) dehydrogenase 7



chr4_-_140222358 0.136 ENST00000505036.1
ENST00000544855.1
ENST00000539002.1
NDUFC1


NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa


chr17_+_48912744 0.136 ENST00000311378.4
WFIKKN2
WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2
chr15_-_64126084 0.136 ENST00000560316.1
ENST00000443617.2
ENST00000560462.1
ENST00000558532.1
ENST00000561400.1
HERC1




HECT and RLD domain containing E3 ubiquitin protein ligase family member 1




chr22_+_40742512 0.135 ENST00000454266.2
ENST00000342312.6
ADSL

adenylosuccinate lyase

chr1_+_26438289 0.134 ENST00000374271.4
ENST00000374269.1
PDIK1L

PDLIM1 interacting kinase 1 like

chrX_-_54070607 0.134 ENST00000338154.6
ENST00000338946.6
PHF8

PHD finger protein 8

chr11_-_64052111 0.133 ENST00000394532.3
ENST00000394531.3
ENST00000309032.3
BAD


BCL2-associated agonist of cell death


chr13_+_73302047 0.132 ENST00000377814.2
ENST00000377815.3
ENST00000390667.5
BORA


bora, aurora kinase A activator


chr9_-_115983641 0.132 ENST00000238256.3
FKBP15
FK506 binding protein 15, 133kDa
chr19_-_40791211 0.132 ENST00000579047.1
AKT2
v-akt murine thymoma viral oncogene homolog 2
chr5_-_37839782 0.131 ENST00000326524.2
ENST00000515058.1
GDNF

glial cell derived neurotrophic factor

chr14_+_77843459 0.131 ENST00000216471.4
SAMD15
sterile alpha motif domain containing 15
chr3_-_53381539 0.131 ENST00000606822.1
ENST00000294241.6
ENST00000607628.1
DCP1A


decapping mRNA 1A


chr8_-_90996837 0.130 ENST00000519426.1
ENST00000265433.3
NBN

nibrin

chr7_+_150020363 0.128 ENST00000359623.4
ENST00000493307.1
LRRC61

leucine rich repeat containing 61


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:2000768 glomerular parietal epithelial cell differentiation(GO:0072139) positive regulation of nephron tubule epithelial cell differentiation(GO:2000768)
0.2 1.0 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.2 0.6 GO:1902361 mitochondrial pyruvate transport(GO:0006850) mitochondrial pyruvate transmembrane transport(GO:1902361)
0.1 0.7 GO:0007079 mitotic chromosome movement towards spindle pole(GO:0007079)
0.1 0.5 GO:0090202 transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
0.1 0.3 GO:0072709 cellular response to sorbitol(GO:0072709)
0.1 0.3 GO:0007439 ectodermal digestive tract development(GO:0007439) embryonic ectodermal digestive tract development(GO:0048611) right lung development(GO:0060458)
0.1 0.3 GO:1905072 apoptotic process involved in endocardial cushion morphogenesis(GO:0003277) intermediate mesoderm morphogenesis(GO:0048390) intermediate mesoderm formation(GO:0048391) intermediate mesodermal cell differentiation(GO:0048392) regulation of cardiac muscle fiber development(GO:0055018) positive regulation of cardiac muscle fiber development(GO:0055020) bud dilation involved in lung branching(GO:0060503) BMP signaling pathway involved in ureter morphogenesis(GO:0061149) renal system segmentation(GO:0061150) BMP signaling pathway involved in renal system segmentation(GO:0061151) pulmonary artery endothelial tube morphogenesis(GO:0061155) regulation of transcription from RNA polymerase II promoter involved in mesonephros development(GO:0061216) BMP signaling pathway involved in nephric duct formation(GO:0071893) negative regulation of branch elongation involved in ureteric bud branching(GO:0072096) negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway(GO:0072097) anterior/posterior pattern specification involved in ureteric bud development(GO:0072099) specification of ureteric bud anterior/posterior symmetry(GO:0072100) specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway(GO:0072101) ureter epithelial cell differentiation(GO:0072192) negative regulation of mesenchymal cell proliferation involved in ureter development(GO:0072200) positive regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901964) cardiac jelly development(GO:1905072) regulation of metanephric S-shaped body morphogenesis(GO:2000004) negative regulation of metanephric S-shaped body morphogenesis(GO:2000005) regulation of metanephric comma-shaped body morphogenesis(GO:2000006) negative regulation of metanephric comma-shaped body morphogenesis(GO:2000007)
0.1 0.3 GO:1900039 positive regulation of cellular response to hypoxia(GO:1900039)
0.1 0.3 GO:0035283 rhombomere 5 development(GO:0021571) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.1 0.9 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.1 0.2 GO:1900111 positive regulation of histone H3-K9 dimethylation(GO:1900111)
0.1 0.3 GO:0051892 negative regulation of cardioblast differentiation(GO:0051892) regulation of cardiac muscle cell myoblast differentiation(GO:2000690) negative regulation of cardiac muscle cell myoblast differentiation(GO:2000691)
0.1 0.5 GO:2000490 negative regulation of hepatic stellate cell activation(GO:2000490)
0.1 0.5 GO:0038110 interleukin-2-mediated signaling pathway(GO:0038110)
0.1 0.3 GO:0086021 SA node cell to atrial cardiac muscle cell communication by electrical coupling(GO:0086021)
0.1 0.4 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
0.1 0.4 GO:0006382 adenosine to inosine editing(GO:0006382)
0.1 0.6 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.1 0.3 GO:2001170 negative regulation of ATP biosynthetic process(GO:2001170)
0.1 0.4 GO:0014005 microglia differentiation(GO:0014004) microglia development(GO:0014005)
0.1 0.1 GO:0032764 negative regulation of mast cell cytokine production(GO:0032764)
0.1 0.3 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.1 0.2 GO:0060086 circadian temperature homeostasis(GO:0060086) positive regulation of bile acid biosynthetic process(GO:0070859) positive regulation of bile acid metabolic process(GO:1904253)
0.1 0.2 GO:0061358 negative regulation of Wnt protein secretion(GO:0061358)
0.1 1.1 GO:0070986 left/right axis specification(GO:0070986)
0.1 0.2 GO:0003249 left ventricular cardiac muscle tissue morphogenesis(GO:0003220) cell proliferation involved in heart valve morphogenesis(GO:0003249) regulation of cell proliferation involved in heart valve morphogenesis(GO:0003250)
0.1 0.2 GO:0035669 TRAM-dependent toll-like receptor signaling pathway(GO:0035668) TRAM-dependent toll-like receptor 4 signaling pathway(GO:0035669)
0.1 0.4 GO:0071169 establishment of protein localization to chromatin(GO:0071169)
0.1 0.7 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.1 0.2 GO:0072658 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.0 0.1 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.0 3.0 GO:0035082 axoneme assembly(GO:0035082)
0.0 0.2 GO:0071484 response to high light intensity(GO:0009644) cellular response to light intensity(GO:0071484)
0.0 0.1 GO:0042450 arginine biosynthetic process via ornithine(GO:0042450)
0.0 0.1 GO:0032240 mRNA export from nucleus in response to heat stress(GO:0031990) negative regulation of nucleobase-containing compound transport(GO:0032240) positive regulation of chromatin assembly or disassembly(GO:0045799) negative regulation of RNA export from nucleus(GO:0046832)
0.0 0.3 GO:0097338 response to clozapine(GO:0097338)
0.0 0.1 GO:0071557 regulation of chromatin silencing at rDNA(GO:0061187) negative regulation of chromatin silencing at rDNA(GO:0061188) histone H3-K27 demethylation(GO:0071557)
0.0 0.1 GO:0052151 positive regulation by symbiont of host apoptotic process(GO:0052151) positive regulation of apoptotic process by virus(GO:0060139)
0.0 0.2 GO:0097089 methyl-branched fatty acid metabolic process(GO:0097089)
0.0 0.2 GO:1902998 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.0 0.3 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.0 0.1 GO:0006424 glutamyl-tRNA aminoacylation(GO:0006424)
0.0 0.1 GO:0046081 dUTP metabolic process(GO:0046080) dUTP catabolic process(GO:0046081)
0.0 0.2 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 0.2 GO:0038018 Wnt receptor catabolic process(GO:0038018) negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.0 0.4 GO:0015886 heme transport(GO:0015886)
0.0 0.2 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.0 0.1 GO:0097156 fasciculation of motor neuron axon(GO:0097156)
0.0 0.1 GO:0006154 adenosine catabolic process(GO:0006154) inosine biosynthetic process(GO:0046103)
0.0 0.1 GO:0097195 pilomotor reflex(GO:0097195)
0.0 0.2 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.0 0.4 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 0.1 GO:0045829 negative regulation of isotype switching(GO:0045829)
0.0 0.2 GO:0017185 peptidyl-lysine hydroxylation(GO:0017185)
0.0 0.1 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.0 0.1 GO:0019243 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.0 0.6 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.3 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.0 1.0 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 0.7 GO:0032703 negative regulation of interleukin-2 production(GO:0032703)
0.0 0.6 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.0 0.2 GO:0032306 regulation of prostaglandin secretion(GO:0032306) positive regulation of prostaglandin secretion(GO:0032308)
0.0 0.2 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.0 0.1 GO:0007113 endomitotic cell cycle(GO:0007113) thrombopoietin-mediated signaling pathway(GO:0038163)
0.0 0.2 GO:0015840 urea transport(GO:0015840)
0.0 1.7 GO:0042733 embryonic digit morphogenesis(GO:0042733)
0.0 1.4 GO:0015949 nucleobase-containing small molecule interconversion(GO:0015949)
0.0 0.1 GO:0072053 renal inner medulla development(GO:0072053) renal outer medulla development(GO:0072054) inner medullary collecting duct development(GO:0072061)
0.0 0.1 GO:1902202 regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.0 0.3 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
0.0 0.1 GO:0021784 postganglionic parasympathetic fiber development(GO:0021784) regulation of ureteric bud formation(GO:0072106) positive regulation of ureteric bud formation(GO:0072107)
0.0 1.3 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 0.4 GO:0060263 regulation of respiratory burst(GO:0060263)
0.0 0.1 GO:0071317 cellular response to morphine(GO:0071315) cellular response to isoquinoline alkaloid(GO:0071317)
0.0 0.4 GO:0050812 acetyl-CoA biosynthetic process from pyruvate(GO:0006086) regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812)
0.0 0.2 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.0 0.4 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.0 0.1 GO:0090116 C-5 methylation of cytosine(GO:0090116)
0.0 0.2 GO:0009048 dosage compensation(GO:0007549) dosage compensation by inactivation of X chromosome(GO:0009048)
0.0 0.1 GO:0038188 cholecystokinin signaling pathway(GO:0038188)
0.0 0.1 GO:0015798 myo-inositol transport(GO:0015798)
0.0 0.2 GO:0052805 histidine catabolic process(GO:0006548) imidazole-containing compound catabolic process(GO:0052805)
0.0 0.1 GO:0035964 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.0 0.1 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.1 GO:0007060 male meiosis chromosome segregation(GO:0007060)
0.0 0.1 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.2 GO:0042996 regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.0 0.1 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.0 0.1 GO:0035711 plasmacytoid dendritic cell activation(GO:0002270) T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840) regulation of restriction endodeoxyribonuclease activity(GO:0032072) T-helper 1 cell activation(GO:0035711)
0.0 0.1 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.0 0.1 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.0 0.1 GO:0016198 axon choice point recognition(GO:0016198)
0.0 0.1 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
0.0 0.2 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.0 0.1 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.0 0.1 GO:0071392 cellular response to estradiol stimulus(GO:0071392)
0.0 0.5 GO:0032878 regulation of establishment or maintenance of cell polarity(GO:0032878)
0.0 0.1 GO:0051182 coenzyme transport(GO:0051182)
0.0 0.1 GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.0 0.1 GO:0007498 mesoderm development(GO:0007498)
0.0 0.1 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.0 0.3 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.1 GO:0061084 regulation of protein refolding(GO:0061083) negative regulation of protein refolding(GO:0061084)
0.0 0.0 GO:0060214 endocardium formation(GO:0060214)
0.0 0.4 GO:0060292 long term synaptic depression(GO:0060292)
0.0 0.1 GO:0051673 membrane disruption in other organism(GO:0051673)
0.0 0.2 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0 0.1 GO:0060075 regulation of resting membrane potential(GO:0060075)
0.0 0.1 GO:0072498 embryonic skeletal joint development(GO:0072498)
0.0 0.1 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.0 0.2 GO:0032042 mitochondrial DNA metabolic process(GO:0032042)
0.0 0.2 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.0 0.0 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.0 0.1 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.3 GO:0035988 chondrocyte proliferation(GO:0035988)
0.0 0.2 GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.0 0.1 GO:0031053 primary miRNA processing(GO:0031053)
0.0 0.1 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.0 0.2 GO:0060044 negative regulation of cardiac muscle cell proliferation(GO:0060044)
0.0 0.3 GO:0046475 glycerophospholipid catabolic process(GO:0046475)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:0001534 radial spoke(GO:0001534)
0.1 0.4 GO:0031933 telomeric heterochromatin(GO:0031933)
0.1 1.0 GO:0097255 R2TP complex(GO:0097255)
0.1 0.7 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.1 1.7 GO:0036038 MKS complex(GO:0036038)
0.1 0.4 GO:0036396 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.1 0.7 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.1 1.3 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.1 0.2 GO:0000229 cytoplasmic chromosome(GO:0000229)
0.1 0.3 GO:0044305 calyx of Held(GO:0044305)
0.0 0.7 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.2 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.0 0.9 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.3 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0 0.2 GO:0001740 Barr body(GO:0001740)
0.0 0.2 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0 0.1 GO:0034665 integrin alpha1-beta1 complex(GO:0034665)
0.0 0.4 GO:0005883 neurofilament(GO:0005883)
0.0 0.4 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.2 GO:0032444 activin responsive factor complex(GO:0032444)
0.0 0.3 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.1 GO:0034678 integrin alpha8-beta1 complex(GO:0034678)
0.0 0.2 GO:0072487 MSL complex(GO:0072487)
0.0 0.4 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.3 GO:0070578 RISC-loading complex(GO:0070578)
0.0 0.6 GO:0031304 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.2 GO:0097418 neurofibrillary tangle(GO:0097418)
0.0 0.5 GO:0060293 P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.0 0.4 GO:0005922 connexon complex(GO:0005922)
0.0 0.4 GO:0001741 XY body(GO:0001741)
0.0 0.1 GO:0070695 FHF complex(GO:0070695)
0.0 0.4 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.2 GO:0032039 integrator complex(GO:0032039)
0.0 0.3 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.1 GO:0000333 telomerase catalytic core complex(GO:0000333)
0.0 0.1 GO:0035976 AP1 complex(GO:0035976)
0.0 0.4 GO:0032982 myosin filament(GO:0032982)
0.0 0.1 GO:0097427 microtubule bundle(GO:0097427)
0.0 0.2 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.1 GO:0031905 early endosome lumen(GO:0031905)
0.0 0.3 GO:0044453 nuclear membrane part(GO:0044453)
0.0 0.1 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 0.2 GO:0032591 dendritic spine membrane(GO:0032591)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.4 GO:0004127 cytidylate kinase activity(GO:0004127)
0.2 1.7 GO:0008158 hedgehog receptor activity(GO:0008158)
0.1 1.1 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.1 0.5 GO:0004911 interleukin-2 receptor activity(GO:0004911) interleukin-2 binding(GO:0019976)
0.1 0.5 GO:0047888 fatty acid peroxidase activity(GO:0047888)
0.1 0.3 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.1 0.4 GO:0097363 protein O-GlcNAc transferase activity(GO:0097363)
0.1 0.2 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.1 0.6 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.1 0.2 GO:0031783 corticotropin hormone receptor binding(GO:0031780) type 5 melanocortin receptor binding(GO:0031783)
0.1 0.2 GO:0003863 alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863)
0.1 0.3 GO:0086020 gap junction channel activity involved in SA node cell-atrial cardiac muscle cell electrical coupling(GO:0086020)
0.1 0.2 GO:0031751 D4 dopamine receptor binding(GO:0031751)
0.1 0.2 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
0.1 0.2 GO:0038047 beta-endorphin receptor activity(GO:0004979) morphine receptor activity(GO:0038047)
0.1 0.4 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.1 0.6 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 0.2 GO:0016418 S-acetyltransferase activity(GO:0016418)
0.0 0.4 GO:0016842 amidine-lyase activity(GO:0016842)
0.0 0.2 GO:0070815 peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.0 0.1 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.0 0.1 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0 0.2 GO:0030899 calcium-dependent ATPase activity(GO:0030899)
0.0 0.2 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.0 0.1 GO:0004019 adenylosuccinate synthase activity(GO:0004019)
0.0 0.2 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.0 0.4 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.1 GO:0004818 glutamate-tRNA ligase activity(GO:0004818)
0.0 0.1 GO:0004170 dUTP diphosphatase activity(GO:0004170)
0.0 0.2 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.0 0.3 GO:0070883 pre-miRNA binding(GO:0070883)
0.0 0.1 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0 0.1 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.0 1.9 GO:0042805 actinin binding(GO:0042805)
0.0 0.2 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 0.2 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.0 0.2 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
0.0 0.4 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.1 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.0 0.1 GO:1990189 peptide-serine-N-acetyltransferase activity(GO:1990189)
0.0 0.2 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.0 0.2 GO:0071253 connexin binding(GO:0071253)
0.0 0.3 GO:0070700 co-receptor binding(GO:0039706) BMP receptor binding(GO:0070700)
0.0 0.4 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.7 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.8 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.1 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.0 0.1 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0 0.2 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 0.1 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.0 0.1 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.0 0.1 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.0 0.1 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 1.3 GO:0051018 protein kinase A binding(GO:0051018)
0.0 0.3 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 0.1 GO:0051185 coenzyme transporter activity(GO:0051185)
0.0 0.1 GO:0004951 cholecystokinin receptor activity(GO:0004951)
0.0 0.1 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0 0.1 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.0 0.1 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.1 GO:0010858 calcium-dependent protein kinase regulator activity(GO:0010858)
0.0 0.1 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.0 1.3 GO:0008186 ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.0 0.0 GO:0071566 UFM1 activating enzyme activity(GO:0071566)
0.0 0.3 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.2 GO:0070569 uridylyltransferase activity(GO:0070569)
0.0 0.2 GO:0043199 sulfate binding(GO:0043199)
0.0 0.0 GO:0008534 oxidized purine nucleobase lesion DNA N-glycosylase activity(GO:0008534)
0.0 0.5 GO:0008171 O-methyltransferase activity(GO:0008171)
0.0 0.0 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.0 0.1 GO:0042954 lipoprotein transporter activity(GO:0042954)
0.0 0.3 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.2 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.2 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.0 0.1 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.0 0.2 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.0 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.0 0.4 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.8 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.2 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 0.0 GO:0008859 exoribonuclease II activity(GO:0008859)
0.0 0.3 GO:0005003 ephrin receptor activity(GO:0005003)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.7 PID_MYC_PATHWAY C-MYC pathway
0.0 1.7 PID_RAC1_PATHWAY RAC1 signaling pathway
0.0 0.4 SIG_IL4RECEPTOR_IN_B_LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.0 0.8 PID_AURORA_A_PATHWAY Aurora A signaling
0.0 0.8 PID_DELTA_NP63_PATHWAY Validated transcriptional targets of deltaNp63 isoforms

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.1 REACTOME_EXTENSION_OF_TELOMERES Genes involved in Extension of Telomeres
0.0 0.4 REACTOME_CDC6_ASSOCIATION_WITH_THE_ORC_ORIGIN_COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 0.4 REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_PDH_COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 1.1 REACTOME_IRON_UPTAKE_AND_TRANSPORT Genes involved in Iron uptake and transport
0.0 0.4 REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.3 REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.2 REACTOME_NEGATIVE_REGULATION_OF_THE_PI3K_AKT_NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.2 REACTOME_ROLE_OF_SECOND_MESSENGERS_IN_NETRIN1_SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.3 REACTOME_REVERSIBLE_HYDRATION_OF_CARBON_DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.5 REACTOME_IL_RECEPTOR_SHC_SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.2 REACTOME_IRAK1_RECRUITS_IKK_COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 0.3 REACTOME_IL_7_SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.4 REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.2 REACTOME_HOMOLOGOUS_RECOMBINATION_REPAIR_OF_REPLICATION_INDEPENDENT_DOUBLE_STRAND_BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.2 REACTOME_REGULATION_OF_RHEB_GTPASE_ACTIVITY_BY_AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.1 REACTOME_AKT_PHOSPHORYLATES_TARGETS_IN_THE_CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol