Motif ID: ESRRB_ESRRG

Z-value: 0.852

Transcription factors associated with ESRRB_ESRRG:

Gene SymbolEntrez IDGene Name
ESRRB ENSG00000119715.10 ESRRB
ESRRG ENSG00000196482.12 ESRRG






Network of associatons between targets according to the STRING database.



First level regulatory network of ESRRB_ESRRG

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr20_+_58179582 2.044 ENST00000371015.1
ENST00000395639.4
PHACTR3

phosphatase and actin regulator 3

chr9_-_39239171 1.314 ENST00000358144.2
CNTNAP3
contactin associated protein-like 3
chr20_+_58152524 1.234 ENST00000359926.3
PHACTR3
phosphatase and actin regulator 3
chr1_-_207119738 1.129 ENST00000356495.4
PIGR
polymeric immunoglobulin receptor
chr10_+_81107271 1.114 ENST00000448165.1
PPIF
peptidylprolyl isomerase F
chr2_+_120189422 1.087 ENST00000306406.4
TMEM37
transmembrane protein 37
chr6_-_97345689 1.009 ENST00000316149.7
NDUFAF4
NADH dehydrogenase (ubiquinone) complex I, assembly factor 4
chr11_+_66624527 0.980 ENST00000393952.3
LRFN4
leucine rich repeat and fibronectin type III domain containing 4
chr4_-_74864386 0.925 ENST00000296027.4
CXCL5
chemokine (C-X-C motif) ligand 5
chr8_-_110704014 0.834 ENST00000529190.1
ENST00000422135.1
ENST00000419099.1
SYBU


syntabulin (syntaxin-interacting)


chr22_-_24110063 0.832 ENST00000520222.1
ENST00000401675.3
CHCHD10

coiled-coil-helix-coiled-coil-helix domain containing 10

chr2_-_31030277 0.741 ENST00000534090.2
ENST00000295055.8
CAPN13

calpain 13

chr10_+_81107216 0.726 ENST00000394579.3
ENST00000225174.3
PPIF

peptidylprolyl isomerase F

chr16_+_11038403 0.705 ENST00000409552.3
CLEC16A
C-type lectin domain family 16, member A
chr18_-_12377283 0.705 ENST00000269143.3
AFG3L2
AFG3-like AAA ATPase 2
chr17_-_79838860 0.628 ENST00000582866.1
RP11-498C9.15
RP11-498C9.15
chr2_-_74374995 0.579 ENST00000295326.4
BOLA3
bolA family member 3
chr9_-_117150243 0.569 ENST00000374088.3
AKNA
AT-hook transcription factor
chr2_-_209028300 0.566 ENST00000304502.4
CRYGA
crystallin, gamma A
chr11_+_57480046 0.561 ENST00000378312.4
ENST00000278422.4
TMX2

thioredoxin-related transmembrane protein 2

chr6_+_107349392 0.536 ENST00000443043.1
ENST00000405204.2
ENST00000311381.5
C6orf203


chromosome 6 open reading frame 203


chr10_+_118187379 0.534 ENST00000369230.3
PNLIPRP3
pancreatic lipase-related protein 3
chr3_+_113666748 0.532 ENST00000330212.3
ENST00000498275.1
ZDHHC23

zinc finger, DHHC-type containing 23

chr10_-_50970382 0.512 ENST00000419399.1
ENST00000432695.1
OGDHL

oxoglutarate dehydrogenase-like

chr17_+_900342 0.511 ENST00000327158.4
TIMM22
translocase of inner mitochondrial membrane 22 homolog (yeast)
chr17_+_4981535 0.508 ENST00000318833.3
ZFP3
ZFP3 zinc finger protein
chr19_-_7293942 0.507 ENST00000341500.5
ENST00000302850.5
INSR

insulin receptor

chr5_-_42811986 0.506 ENST00000511224.1
ENST00000507920.1
ENST00000510965.1
SEPP1


selenoprotein P, plasma, 1


chr10_-_50970322 0.476 ENST00000374103.4
OGDHL
oxoglutarate dehydrogenase-like
chr17_+_79670386 0.470 ENST00000541223.1
ENST00000571730.1
ENST00000333676.3
SLC25A10
SLC25A10
MRPL12
solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
Mitochondrial dicarboxylate carrier; Uncharacterized protein; cDNA FLJ60124, highly similar to Mitochondrial dicarboxylate carrier
mitochondrial ribosomal protein L12
chr5_-_42812143 0.465 ENST00000514985.1
SEPP1
selenoprotein P, plasma, 1
chr2_+_198365095 0.463 ENST00000409468.1
HSPE1
heat shock 10kDa protein 1
chr1_-_153433120 0.460 ENST00000368723.3
S100A7
S100 calcium binding protein A7
chr1_+_161195781 0.432 ENST00000367988.3
TOMM40L
translocase of outer mitochondrial membrane 40 homolog (yeast)-like
chr2_-_238499303 0.432 ENST00000409576.1
RAB17
RAB17, member RAS oncogene family
chr11_+_66059339 0.427 ENST00000327259.4
TMEM151A
transmembrane protein 151A
chr11_-_84634217 0.408 ENST00000524982.1
DLG2
discs, large homolog 2 (Drosophila)
chr19_+_46850320 0.402 ENST00000391919.1
PPP5C
protein phosphatase 5, catalytic subunit
chr3_+_184037466 0.390 ENST00000441154.1
EIF4G1
eukaryotic translation initiation factor 4 gamma, 1
chr19_+_46850251 0.389 ENST00000012443.4
PPP5C
protein phosphatase 5, catalytic subunit
chr5_+_175085033 0.388 ENST00000377291.2
HRH2
histamine receptor H2
chr1_-_211752073 0.388 ENST00000367001.4
SLC30A1
solute carrier family 30 (zinc transporter), member 1
chr5_-_137911049 0.385 ENST00000297185.3
HSPA9
heat shock 70kDa protein 9 (mortalin)
chr1_+_207226574 0.383 ENST00000367080.3
ENST00000367079.2
PFKFB2

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2

chr17_+_46970178 0.381 ENST00000393366.2
ENST00000506855.1
ATP5G1

ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)

chr22_+_29702996 0.381 ENST00000406549.3
ENST00000360113.2
ENST00000341313.6
ENST00000403764.1
ENST00000471961.1
ENST00000407854.1
GAS2L1





growth arrest-specific 2 like 1





chr22_+_31518938 0.376 ENST00000412985.1
ENST00000331075.5
ENST00000412277.2
ENST00000420017.1
ENST00000400294.2
ENST00000405300.1
ENST00000404390.3
INPP5J






inositol polyphosphate-5-phosphatase J






chr19_-_55574538 0.376 ENST00000415061.3
RDH13
retinol dehydrogenase 13 (all-trans/9-cis)
chr3_-_123339418 0.375 ENST00000583087.1
MYLK
myosin light chain kinase
chr17_+_46970134 0.375 ENST00000503641.1
ENST00000514808.1
ATP5G1

ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)

chr4_-_16077741 0.374 ENST00000447510.2
ENST00000540805.1
ENST00000539194.1
PROM1


prominin 1


chr15_+_78441663 0.371 ENST00000299518.2
ENST00000558554.1
ENST00000557826.1
ENST00000561279.1
ENST00000559186.1
ENST00000560770.1
ENST00000559881.1
ENST00000559205.1
ENST00000441490.2
IDH3A








isocitrate dehydrogenase 3 (NAD+) alpha








chr17_+_36858694 0.370 ENST00000563897.1
CTB-58E17.1
CTB-58E17.1
chr3_-_179322436 0.368 ENST00000392659.2
ENST00000476781.1
MRPL47

mitochondrial ribosomal protein L47

chr9_-_130679257 0.368 ENST00000361444.3
ENST00000335791.5
ENST00000343609.2
ST6GALNAC4


ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4


chr1_-_241683001 0.367 ENST00000366560.3
FH
fumarate hydratase
chr9_-_130637244 0.365 ENST00000373156.1
AK1
adenylate kinase 1
chr14_-_107114267 0.364 ENST00000454421.2
IGHV3-64
immunoglobulin heavy variable 3-64
chr17_+_46970127 0.363 ENST00000355938.5
ATP5G1
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)
chr3_-_179322416 0.361 ENST00000259038.2
MRPL47
mitochondrial ribosomal protein L47
chr2_-_176046391 0.358 ENST00000392541.3
ENST00000409194.1
ATP5G3

ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9)

chr3_-_123339343 0.353 ENST00000578202.1
MYLK
myosin light chain kinase
chr20_-_13765526 0.349 ENST00000202816.1
ESF1
ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae)
chr3_-_14166316 0.347 ENST00000396914.3
ENST00000295767.5
CHCHD4

coiled-coil-helix-coiled-coil-helix domain containing 4

chr6_+_31916733 0.343 ENST00000483004.1
CFB
complement factor B
chr2_-_42721110 0.342 ENST00000394973.4
ENST00000306078.1
KCNG3

potassium voltage-gated channel, subfamily G, member 3

chr3_+_184038073 0.341 ENST00000428387.1
ENST00000434061.2
EIF4G1

eukaryotic translation initiation factor 4 gamma, 1

chr10_+_112257596 0.334 ENST00000369583.3
DUSP5
dual specificity phosphatase 5
chr4_-_819901 0.331 ENST00000304062.6
CPLX1
complexin 1
chr11_-_111957451 0.330 ENST00000504148.2
ENST00000541231.1
TIMM8B

translocase of inner mitochondrial membrane 8 homolog B (yeast)

chr10_-_101190202 0.328 ENST00000543866.1
ENST00000370508.5
GOT1

glutamic-oxaloacetic transaminase 1, soluble

chr15_+_76352178 0.324 ENST00000388942.3
C15orf27
chromosome 15 open reading frame 27
chr16_+_2588012 0.321 ENST00000354836.5
ENST00000389224.3
PDPK1

3-phosphoinositide dependent protein kinase-1

chr17_+_5185552 0.318 ENST00000262477.6
ENST00000408982.2
ENST00000575991.1
ENST00000537505.1
ENST00000546142.2
RABEP1




rabaptin, RAB GTPase binding effector protein 1




chr1_+_153388993 0.318 ENST00000368729.4
S100A7A
S100 calcium binding protein A7A
chr3_+_179322573 0.317 ENST00000493866.1
ENST00000472629.1
ENST00000482604.1
NDUFB5


NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa


chr12_+_54378923 0.314 ENST00000303460.4
HOXC10
homeobox C10
chr1_+_152881014 0.314 ENST00000368764.3
ENST00000392667.2
IVL

involucrin

chr16_+_691792 0.314 ENST00000307650.4
FAM195A
family with sequence similarity 195, member A
chr3_-_52443799 0.314 ENST00000470173.1
ENST00000296288.5
BAP1

BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)

chr17_-_29624343 0.313 ENST00000247271.4
OMG
oligodendrocyte myelin glycoprotein
chr6_-_87804815 0.301 ENST00000369582.2
CGA
glycoprotein hormones, alpha polypeptide
chr8_+_67341239 0.300 ENST00000320270.2
RRS1
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
chr3_-_51975942 0.298 ENST00000232888.6
RRP9
ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast)
chr8_+_67405755 0.298 ENST00000521495.1
C8orf46
chromosome 8 open reading frame 46
chr7_-_132261223 0.294 ENST00000423507.2
PLXNA4
plexin A4
chr10_+_105156364 0.294 ENST00000369797.3
PDCD11
programmed cell death 11
chr2_-_238499725 0.290 ENST00000264601.3
RAB17
RAB17, member RAS oncogene family
chr8_+_99956759 0.290 ENST00000522510.1
ENST00000457907.2
OSR2

odd-skipped related transciption factor 2

chr11_-_10590238 0.288 ENST00000256178.3
LYVE1
lymphatic vessel endothelial hyaluronan receptor 1
chr2_-_238499131 0.288 ENST00000538644.1
RAB17
RAB17, member RAS oncogene family
chrX_-_47489244 0.287 ENST00000469388.1
ENST00000396992.3
ENST00000377005.2
CFP


complement factor properdin


chr5_-_19988339 0.285 ENST00000382275.1
CDH18
cadherin 18, type 2
chr7_+_37960163 0.284 ENST00000199448.4
ENST00000559325.1
ENST00000423717.1
EPDR1


ependymin related 1


chr16_-_57481278 0.284 ENST00000567751.1
ENST00000568940.1
ENST00000563341.1
ENST00000565961.1
ENST00000569370.1
ENST00000567518.1
ENST00000565786.1
ENST00000394391.4
CIAPIN1







cytokine induced apoptosis inhibitor 1







chr17_+_37821593 0.283 ENST00000578283.1
TCAP
titin-cap
chr7_+_39605966 0.280 ENST00000223273.2
ENST00000448268.1
ENST00000432096.2
YAE1D1


Yae1 domain containing 1


chr11_+_6411670 0.278 ENST00000530395.1
ENST00000527275.1
SMPD1

sphingomyelin phosphodiesterase 1, acid lysosomal

chr7_+_123241908 0.276 ENST00000434204.1
ENST00000437535.1
ENST00000451215.1
ASB15


ankyrin repeat and SOCS box containing 15


chr3_+_160473996 0.273 ENST00000498165.1
PPM1L
protein phosphatase, Mg2+/Mn2+ dependent, 1L
chr19_-_9006766 0.271 ENST00000599436.1
MUC16
mucin 16, cell surface associated
chr1_+_29138654 0.271 ENST00000234961.2
OPRD1
opioid receptor, delta 1
chr2_+_198365122 0.269 ENST00000604458.1
HSPE1-MOB4
HSPE1-MOB4 readthrough
chr10_+_116853201 0.267 ENST00000527407.1
ATRNL1
attractin-like 1
chr10_-_120925054 0.265 ENST00000419372.1
ENST00000369131.4
ENST00000330036.6
ENST00000355697.2
SFXN4



sideroflexin 4



chr4_-_819880 0.264 ENST00000505203.1
CPLX1
complexin 1
chr19_+_17416609 0.264 ENST00000602206.1
MRPL34
mitochondrial ribosomal protein L34
chr20_-_3748363 0.261 ENST00000217195.8
C20orf27
chromosome 20 open reading frame 27
chr22_+_40573921 0.261 ENST00000454349.2
ENST00000335727.9
TNRC6B

trinucleotide repeat containing 6B

chr1_+_9648921 0.259 ENST00000377376.4
ENST00000340305.5
ENST00000340381.6
TMEM201


transmembrane protein 201


chr20_-_3748416 0.258 ENST00000399672.1
C20orf27
chromosome 20 open reading frame 27
chr22_-_47134077 0.257 ENST00000541677.1
ENST00000216264.8
CERK

ceramide kinase

chr7_-_92848858 0.255 ENST00000440868.1
HEPACAM2
HEPACAM family member 2
chr7_-_92848878 0.255 ENST00000341723.4
HEPACAM2
HEPACAM family member 2
chr1_+_19923454 0.254 ENST00000322753.6
ENST00000602662.1
ENST00000602293.1
MINOS1
MINOS1-NBL1

mitochondrial inner membrane organizing system 1
MINOS1-NBL1 readthrough

chr20_+_13765596 0.254 ENST00000378106.5
ENST00000463598.1
NDUFAF5

NADH dehydrogenase (ubiquinone) complex I, assembly factor 5

chrX_-_150067069 0.253 ENST00000466436.1
CD99L2
CD99 molecule-like 2
chr12_-_120554534 0.244 ENST00000538903.1
ENST00000534951.1
RAB35

RAB35, member RAS oncogene family

chr14_-_21491477 0.244 ENST00000298684.5
ENST00000557169.1
ENST00000553563.1
NDRG2


NDRG family member 2


chr8_-_145115584 0.242 ENST00000426825.1
OPLAH
5-oxoprolinase (ATP-hydrolysing)
chr1_+_156163880 0.239 ENST00000359511.4
ENST00000423538.2
SLC25A44

solute carrier family 25, member 44

chr2_+_86426478 0.236 ENST00000254644.8
ENST00000605125.1
ENST00000337109.4
ENST00000409180.1
MRPL35



mitochondrial ribosomal protein L35



chr5_+_218356 0.233 ENST00000264932.6
ENST00000504309.1
ENST00000510361.1
SDHA


succinate dehydrogenase complex, subunit A, flavoprotein (Fp)


chr1_+_46640750 0.233 ENST00000372003.1
TSPAN1
tetraspanin 1
chr12_+_58176525 0.231 ENST00000543727.1
ENST00000540550.1
ENST00000323833.8
ENST00000350762.5
ENST00000550559.1
ENST00000548851.1
ENST00000434359.1
ENST00000457189.1
TSFM







Ts translation elongation factor, mitochondrial







chr16_-_4588469 0.230 ENST00000588381.1
ENST00000563332.2
CDIP1

cell death-inducing p53 target 1

chr5_+_140227357 0.230 ENST00000378122.3
PCDHA9
protocadherin alpha 9
chr3_+_113465866 0.229 ENST00000273398.3
ENST00000538620.1
ENST00000496747.1
ENST00000475322.1
ATP6V1A



ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A



chr20_+_18447771 0.226 ENST00000377603.4
POLR3F
polymerase (RNA) III (DNA directed) polypeptide F, 39 kDa
chr15_+_59903975 0.222 ENST00000560585.1
ENST00000396065.1
GCNT3

glucosaminyl (N-acetyl) transferase 3, mucin type

chr17_-_39743139 0.221 ENST00000167586.6
KRT14
keratin 14
chr1_-_203144941 0.221 ENST00000255416.4
MYBPH
myosin binding protein H
chr21_-_27107198 0.220 ENST00000400094.1
ATP5J
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6
chr19_+_55105085 0.220 ENST00000251372.3
ENST00000453777.1
LILRA1

leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1

chr14_-_106330072 0.219 ENST00000488476.1
IGHJ5
immunoglobulin heavy joining 5
chr8_+_99956662 0.217 ENST00000523368.1
ENST00000297565.4
ENST00000435298.2
OSR2


odd-skipped related transciption factor 2


chr2_+_191792376 0.217 ENST00000409428.1
ENST00000409215.1
GLS

glutaminase

chr14_-_106330458 0.217 ENST00000461719.1
IGHJ4
immunoglobulin heavy joining 4
chr22_-_39239987 0.214 ENST00000333039.2
NPTXR
neuronal pentraxin receptor
chr19_-_4517613 0.213 ENST00000301286.3
PLIN4
perilipin 4
chr7_-_131241361 0.211 ENST00000378555.3
ENST00000322985.9
ENST00000541194.1
ENST00000537928.1
PODXL



podocalyxin-like



chr2_+_145425573 0.210 ENST00000600064.1
ENST00000597670.1
ENST00000414256.1
ENST00000599187.1
ENST00000451774.1
ENST00000599072.1
ENST00000596589.1
ENST00000597893.1
TEX41







testis expressed 41 (non-protein coding)







chr8_+_66933779 0.209 ENST00000276570.5
DNAJC5B
DnaJ (Hsp40) homolog, subfamily C, member 5 beta
chr4_-_1723040 0.208 ENST00000382936.3
ENST00000536901.1
ENST00000303277.2
TMEM129


transmembrane protein 129


chr1_+_206858328 0.207 ENST00000367103.3
MAPKAPK2
mitogen-activated protein kinase-activated protein kinase 2
chr8_+_110346546 0.206 ENST00000521662.1
ENST00000521688.1
ENST00000520147.1
ENY2


enhancer of yellow 2 homolog (Drosophila)


chr16_+_11038345 0.206 ENST00000409790.1
CLEC16A
C-type lectin domain family 16, member A
chr22_+_20104947 0.205 ENST00000402752.1
RANBP1
RAN binding protein 1
chr19_+_45394477 0.204 ENST00000252487.5
ENST00000405636.2
ENST00000592434.1
ENST00000426677.2
ENST00000589649.1
TOMM40




translocase of outer mitochondrial membrane 40 homolog (yeast)




chr15_-_83621435 0.203 ENST00000450735.2
ENST00000426485.1
ENST00000399166.2
ENST00000304231.8
HOMER2



homer homolog 2 (Drosophila)



chr11_-_133826852 0.203 ENST00000533871.2
ENST00000321016.8
IGSF9B

immunoglobulin superfamily, member 9B

chr5_+_80529104 0.199 ENST00000254035.4
ENST00000511719.1
ENST00000437669.1
ENST00000424301.2
ENST00000505060.1
CKMT2




creatine kinase, mitochondrial 2 (sarcomeric)




chr2_-_170430277 0.199 ENST00000438035.1
ENST00000453929.2
FASTKD1

FAST kinase domains 1

chr2_-_44223138 0.199 ENST00000260665.7
LRPPRC
leucine-rich pentatricopeptide repeat containing
chr15_+_43985725 0.198 ENST00000413453.2
CKMT1A
creatine kinase, mitochondrial 1A
chrX_-_129299638 0.198 ENST00000535724.1
ENST00000346424.2
AIFM1

apoptosis-inducing factor, mitochondrion-associated, 1

chr11_+_6411636 0.198 ENST00000299397.3
ENST00000356761.2
ENST00000342245.4
SMPD1


sphingomyelin phosphodiesterase 1, acid lysosomal


chr16_-_84273304 0.195 ENST00000308251.4
ENST00000568181.1
KCNG4

potassium voltage-gated channel, subfamily G, member 4

chr2_-_220119280 0.195 ENST00000392088.2
TUBA4A
tubulin, alpha 4a
chr17_+_46126135 0.194 ENST00000361665.3
ENST00000585062.1
NFE2L1

nuclear factor, erythroid 2-like 1

chr20_-_48532019 0.194 ENST00000289431.5
SPATA2
spermatogenesis associated 2
chr5_+_66254698 0.193 ENST00000405643.1
ENST00000407621.1
ENST00000432426.1
MAST4


microtubule associated serine/threonine kinase family member 4


chr16_-_15472151 0.193 ENST00000360151.4
ENST00000543801.1
NPIPA5

nuclear pore complex interacting protein family, member A5

chr3_-_167452262 0.192 ENST00000487947.2
PDCD10
programmed cell death 10
chr15_+_43885252 0.192 ENST00000453782.1
ENST00000300283.6
ENST00000437924.1
ENST00000450086.2
CKMT1B



creatine kinase, mitochondrial 1B



chr15_+_43985084 0.191 ENST00000434505.1
ENST00000411750.1
CKMT1A

creatine kinase, mitochondrial 1A

chr2_-_170430366 0.190 ENST00000453153.2
ENST00000445210.1
FASTKD1

FAST kinase domains 1

chr17_-_2614927 0.190 ENST00000435359.1
CLUH
clustered mitochondria (cluA/CLU1) homolog
chr4_-_170947522 0.189 ENST00000361618.3
MFAP3L
microfibrillar-associated protein 3-like
chr11_+_86667117 0.187 ENST00000531827.1
RP11-736K20.6
RP11-736K20.6
chr9_+_95997205 0.186 ENST00000411624.1
WNK2
WNK lysine deficient protein kinase 2
chr7_-_95225768 0.186 ENST00000005178.5
PDK4
pyruvate dehydrogenase kinase, isozyme 4
chr20_+_54933971 0.186 ENST00000371384.3
ENST00000437418.1
FAM210B

family with sequence similarity 210, member B

chrX_-_150067272 0.185 ENST00000355149.3
ENST00000437787.2
CD99L2

CD99 molecule-like 2

chr3_-_50605077 0.185 ENST00000426034.1
ENST00000441239.1
C3orf18

chromosome 3 open reading frame 18

chr16_-_67427389 0.185 ENST00000562206.1
ENST00000290942.5
ENST00000393957.2
TPPP3


tubulin polymerization-promoting protein family member 3


chr1_-_23504176 0.185 ENST00000302291.4
LUZP1
leucine zipper protein 1
chr8_-_93107696 0.183 ENST00000436581.2
ENST00000520583.1
ENST00000519061.1
RUNX1T1


runt-related transcription factor 1; translocated to, 1 (cyclin D-related)


chr14_-_70546897 0.183 ENST00000394330.2
ENST00000533541.1
ENST00000216568.7
SLC8A3


solute carrier family 8 (sodium/calcium exchanger), member 3


chr18_-_19284724 0.182 ENST00000580981.1
ENST00000289119.2
ABHD3

abhydrolase domain containing 3

chr17_+_38219063 0.181 ENST00000584985.1
ENST00000264637.4
ENST00000450525.2
THRA


thyroid hormone receptor, alpha


chrX_-_150067173 0.181 ENST00000370377.3
ENST00000320893.6
CD99L2

CD99 molecule-like 2

chr12_+_15125954 0.181 ENST00000266395.2
PDE6H
phosphodiesterase 6H, cGMP-specific, cone, gamma
chr4_+_44680429 0.180 ENST00000281543.5
GUF1
GUF1 GTPase homolog (S. cerevisiae)
chrX_-_43741594 0.180 ENST00000536181.1
ENST00000378069.4
MAOB

monoamine oxidase B

chr16_-_29874211 0.178 ENST00000563415.1
CDIPT
CDP-diacylglycerol--inositol 3-phosphatidyltransferase
chr1_-_200992827 0.176 ENST00000332129.2
ENST00000422435.2
KIF21B

kinesin family member 21B

chr22_+_25465786 0.176 ENST00000401395.1
KIAA1671
KIAA1671
chr21_-_27107283 0.175 ENST00000284971.3
ENST00000400099.1
ATP5J

ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6

chr15_-_77988485 0.175 ENST00000561030.1
LINGO1
leucine rich repeat and Ig domain containing 1
chr11_+_278365 0.174 ENST00000534750.1
NLRP6
NLR family, pyrin domain containing 6
chr1_-_110052302 0.173 ENST00000369864.4
ENST00000369862.1
AMIGO1

adhesion molecule with Ig-like domain 1

chr21_-_27107344 0.173 ENST00000457143.2
ATP5J
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6
chr12_+_125478241 0.172 ENST00000341446.8
BRI3BP
BRI3 binding protein
chr14_-_21492113 0.172 ENST00000554094.1
NDRG2
NDRG family member 2
chr3_-_167813132 0.172 ENST00000309027.4
GOLIM4
golgi integral membrane protein 4
chrX_+_150866779 0.172 ENST00000370353.3
PRRG3
proline rich Gla (G-carboxyglutamic acid) 3 (transmembrane)
chr1_-_145076186 0.170 ENST00000369348.3
PDE4DIP
phosphodiesterase 4D interacting protein
chr4_-_122872909 0.169 ENST00000379645.3
TRPC3
transient receptor potential cation channel, subfamily C, member 3
chr1_-_241520525 0.167 ENST00000366565.1
RGS7
regulator of G-protein signaling 7

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.8 GO:2000276 negative regulation of oxidative phosphorylation uncoupler activity(GO:2000276)
0.4 2.2 GO:0002415 immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
0.3 0.8 GO:0006106 fumarate metabolic process(GO:0006106)
0.2 0.7 GO:0015729 thiosulfate transport(GO:0015709) oxaloacetate transport(GO:0015729) malate transport(GO:0015743) malate transmembrane transport(GO:0071423) oxaloacetate(2-) transmembrane transport(GO:1902356)
0.2 0.6 GO:0021793 chemorepulsion of branchiomotor axon(GO:0021793)
0.2 0.9 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.1 0.8 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.1 0.5 GO:1990535 transformation of host cell by virus(GO:0019087) neuron projection maintenance(GO:1990535)
0.1 0.1 GO:0006533 aspartate catabolic process(GO:0006533)
0.1 0.3 GO:0018153 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.1 0.5 GO:0036023 limb joint morphogenesis(GO:0036022) embryonic skeletal limb joint morphogenesis(GO:0036023)
0.1 0.4 GO:0009644 response to high light intensity(GO:0009644)
0.1 0.4 GO:2000768 glomerular parietal epithelial cell differentiation(GO:0072139) positive regulation of nephron tubule epithelial cell differentiation(GO:2000768)
0.1 0.7 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.1 0.3 GO:0035521 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.1 0.4 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.1 0.3 GO:0002155 regulation of thyroid hormone mediated signaling pathway(GO:0002155)
0.1 0.2 GO:0018194 N-terminal protein amino acid methylation(GO:0006480) N-terminal peptidyl-alanine methylation(GO:0018011) N-terminal peptidyl-alanine trimethylation(GO:0018012) N-terminal peptidyl-glycine methylation(GO:0018013) N-terminal peptidyl-proline dimethylation(GO:0018016) peptidyl-alanine modification(GO:0018194) N-terminal peptidyl-proline methylation(GO:0035568) N-terminal peptidyl-serine methylation(GO:0035570) N-terminal peptidyl-serine dimethylation(GO:0035572) N-terminal peptidyl-serine trimethylation(GO:0035573)
0.1 3.1 GO:0042407 cristae formation(GO:0042407)
0.1 0.5 GO:0023021 termination of signal transduction(GO:0023021)
0.1 0.1 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.1 0.2 GO:0032242 regulation of nucleoside transport(GO:0032242) negative regulation of neurotrophin production(GO:0032900)
0.1 0.4 GO:1903301 fructose 2,6-bisphosphate metabolic process(GO:0006003) positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.1 0.2 GO:1900365 positive regulation of mRNA polyadenylation(GO:1900365)
0.1 0.2 GO:0021503 neural fold bending(GO:0021503)
0.1 0.7 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.1 0.3 GO:0060356 leucine import(GO:0060356)
0.1 0.3 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
0.1 0.5 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.1 0.3 GO:0008065 establishment of blood-nerve barrier(GO:0008065)
0.1 0.2 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.1 0.5 GO:0010820 positive regulation of T cell chemotaxis(GO:0010820)
0.1 0.2 GO:0003050 regulation of systemic arterial blood pressure by atrial natriuretic peptide(GO:0003050)
0.0 0.2 GO:0000957 mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
0.0 0.0 GO:0033140 negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140)
0.0 0.3 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.0 0.1 GO:1904048 regulation of spontaneous neurotransmitter secretion(GO:1904048)
0.0 0.2 GO:0006172 ADP biosynthetic process(GO:0006172)
0.0 0.1 GO:0031630 regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
0.0 0.2 GO:1903281 protein transport into plasma membrane raft(GO:0044861) positive regulation of calcium:sodium antiporter activity(GO:1903281) positive regulation of potassium ion import(GO:1903288)
0.0 0.1 GO:0009405 pathogenesis(GO:0009405)
0.0 0.4 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.3 GO:0061687 detoxification of inorganic compound(GO:0061687) stress response to metal ion(GO:0097501)
0.0 0.1 GO:1901526 positive regulation of macromitophagy(GO:1901526) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925)
0.0 0.1 GO:0097252 renal albumin absorption(GO:0097018) oligodendrocyte apoptotic process(GO:0097252) regulation of renal albumin absorption(GO:2000532)
0.0 0.2 GO:0006543 glutamine catabolic process(GO:0006543)
0.0 0.3 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.0 0.4 GO:1902037 negative regulation of hematopoietic stem cell differentiation(GO:1902037)
0.0 0.7 GO:0090360 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.0 0.2 GO:0002159 desmosome assembly(GO:0002159)
0.0 0.1 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 0.8 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.2 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.0 0.3 GO:0098706 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.0 0.1 GO:1903861 regulation of dendrite extension(GO:1903859) positive regulation of dendrite extension(GO:1903861)
0.0 1.4 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.0 0.1 GO:0071422 succinate transport(GO:0015744) succinate transmembrane transport(GO:0071422)
0.0 0.3 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055)
0.0 0.5 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.0 0.3 GO:0017185 peptidyl-lysine hydroxylation(GO:0017185)
0.0 0.9 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023)
0.0 2.8 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.3 GO:0072321 chaperone-mediated protein transport(GO:0072321)
0.0 0.1 GO:0019482 beta-alanine metabolic process(GO:0019482)
0.0 0.4 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.0 0.1 GO:0048597 B cell negative selection(GO:0002352) post-embryonic camera-type eye morphogenesis(GO:0048597)
0.0 0.8 GO:0051084 'de novo' posttranslational protein folding(GO:0051084)
0.0 0.2 GO:0090649 response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650) regulation of apoptotic DNA fragmentation(GO:1902510) response to aldosterone(GO:1904044)
0.0 0.2 GO:1903244 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244)
0.0 0.1 GO:1902809 regulation of skeletal muscle fiber differentiation(GO:1902809)
0.0 0.3 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.0 0.1 GO:0072429 response to intra-S DNA damage checkpoint signaling(GO:0072429)
0.0 0.1 GO:0061300 cerebellum vasculature development(GO:0061300)
0.0 0.2 GO:0010269 response to selenium ion(GO:0010269)
0.0 0.2 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.2 GO:0050812 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812)
0.0 0.2 GO:0048875 chemical homeostasis within a tissue(GO:0048875)
0.0 0.4 GO:0070129 regulation of mitochondrial translation(GO:0070129)
0.0 0.0 GO:0052314 phytoalexin metabolic process(GO:0052314)
0.0 0.1 GO:0090234 regulation of kinetochore assembly(GO:0090234)
0.0 0.2 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.2 GO:1990034 calcium ion export from cell(GO:1990034)
0.0 0.1 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.0 0.1 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.0 0.3 GO:0070255 regulation of mucus secretion(GO:0070255)
0.0 0.3 GO:0042535 positive regulation of tumor necrosis factor biosynthetic process(GO:0042535)
0.0 0.2 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.0 0.1 GO:0035900 response to isolation stress(GO:0035900)
0.0 0.2 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 0.3 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.1 GO:0046684 corticospinal neuron axon guidance(GO:0021966) response to pyrethroid(GO:0046684)
0.0 0.4 GO:0040033 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.0 0.3 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.0 0.2 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.0 0.2 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.0 0.2 GO:0070601 centromeric sister chromatid cohesion(GO:0070601)
0.0 0.4 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.0 0.2 GO:0006600 creatine metabolic process(GO:0006600)
0.0 0.1 GO:0010748 regulation of plasma membrane long-chain fatty acid transport(GO:0010746) negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748)
0.0 0.2 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.0 0.9 GO:0006754 ATP biosynthetic process(GO:0006754)
0.0 0.2 GO:0014052 regulation of gamma-aminobutyric acid secretion(GO:0014052)
0.0 0.1 GO:0070995 NADPH oxidation(GO:0070995)
0.0 0.4 GO:0097286 iron ion import(GO:0097286)
0.0 0.1 GO:1901908 diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.0 0.1 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
0.0 0.1 GO:0032764 negative regulation of mast cell cytokine production(GO:0032764)
0.0 0.3 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.0 0.2 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.0 0.1 GO:0030186 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.0 0.1 GO:1904729 regulation of intestinal cholesterol absorption(GO:0030300) regulation of intestinal lipid absorption(GO:1904729)
0.0 0.5 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.1 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
0.0 0.2 GO:0097011 cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011) response to granulocyte macrophage colony-stimulating factor(GO:0097012)
0.0 0.0 GO:0018874 benzoate metabolic process(GO:0018874)
0.0 0.3 GO:0007097 nuclear migration(GO:0007097)
0.0 0.4 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.0 0.4 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.0 0.2 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.0 0.1 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.0 0.2 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0 0.2 GO:0098828 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0 0.0 GO:0070173 regulation of enamel mineralization(GO:0070173)
0.0 0.3 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.1 GO:0038031 non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.0 0.2 GO:0009125 nucleoside monophosphate catabolic process(GO:0009125)
0.0 0.1 GO:0045763 negative regulation of cellular amino acid metabolic process(GO:0045763) regulation of glutamate metabolic process(GO:2000211)
0.0 0.1 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 0.0 GO:0051563 smooth endoplasmic reticulum calcium ion homeostasis(GO:0051563)
0.0 0.0 GO:1903215 negative regulation of protein targeting to mitochondrion(GO:1903215)
0.0 0.1 GO:0034334 adherens junction maintenance(GO:0034334)
0.0 0.2 GO:0061635 regulation of protein complex stability(GO:0061635)
0.0 0.3 GO:0000466 maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000466)
0.0 0.1 GO:0045656 negative regulation of monocyte differentiation(GO:0045656)
0.0 0.2 GO:0048642 negative regulation of skeletal muscle tissue development(GO:0048642)
0.0 0.1 GO:2001033 negative regulation of double-strand break repair via nonhomologous end joining(GO:2001033)
0.0 0.1 GO:0034196 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.0 1.4 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.0 0.3 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 0.2 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.0 0.8 GO:0061178 regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061178)
0.0 0.4 GO:0097120 receptor localization to synapse(GO:0097120)
0.0 0.3 GO:0001696 gastric acid secretion(GO:0001696)
0.0 0.2 GO:0036295 cellular response to increased oxygen levels(GO:0036295)
0.0 0.1 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.0 0.1 GO:0015014 protein sulfation(GO:0006477) heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.1 GO:0098501 polynucleotide dephosphorylation(GO:0098501)
0.0 0.8 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.1 GO:0070544 histone H3-K36 demethylation(GO:0070544)
0.0 0.0 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.2 GO:0002281 macrophage activation involved in immune response(GO:0002281)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.1 GO:0005753 mitochondrial proton-transporting ATP synthase complex(GO:0005753)
0.1 0.5 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
0.1 0.8 GO:1990635 proximal dendrite(GO:1990635)
0.1 0.4 GO:0045283 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.1 1.0 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.1 0.6 GO:0070554 synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.1 0.4 GO:0005899 insulin receptor complex(GO:0005899)
0.1 0.6 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.1 0.3 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.1 0.8 GO:0097433 dense body(GO:0097433)
0.1 0.3 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.1 0.5 GO:0061617 MICOS complex(GO:0061617)
0.1 0.2 GO:0005873 plus-end kinesin complex(GO:0005873)
0.1 0.2 GO:0044753 amphisome(GO:0044753)
0.1 0.4 GO:0045239 tricarboxylic acid cycle enzyme complex(GO:0045239)
0.0 0.2 GO:0045272 plasma membrane respiratory chain complex I(GO:0045272)
0.0 0.2 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.0 0.9 GO:0036020 endolysosome membrane(GO:0036020)
0.0 0.2 GO:0032279 asymmetric synapse(GO:0032279)
0.0 0.7 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.1 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.0 0.3 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0 0.9 GO:0031304 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.4 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.3 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.0 0.6 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 2.1 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.2 GO:0098560 cytoplasmic side of late endosome membrane(GO:0098560)
0.0 0.1 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.0 0.1 GO:1990876 cytoplasmic side of nuclear pore(GO:1990876)
0.0 0.4 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.1 GO:0071749 IgA immunoglobulin complex(GO:0071745) IgA immunoglobulin complex, circulating(GO:0071746) monomeric IgA immunoglobulin complex(GO:0071748) polymeric IgA immunoglobulin complex(GO:0071749) secretory IgA immunoglobulin complex(GO:0071751)
0.0 0.2 GO:0031415 NatA complex(GO:0031415)
0.0 0.2 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.2 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0 0.5 GO:0042599 lamellar body(GO:0042599)
0.0 1.5 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.2 GO:0032010 phagolysosome(GO:0032010)
0.0 0.3 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.1 GO:0044326 dendritic spine neck(GO:0044326)
0.0 0.2 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.1 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.0 0.1 GO:0098574 cytoplasmic side of lysosomal membrane(GO:0098574)
0.0 0.2 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 0.1 GO:0097427 microtubule bundle(GO:0097427)
0.0 0.1 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.0 0.4 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 1.5 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 0.2 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.4 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 2.7 GO:0016363 nuclear matrix(GO:0016363)
0.0 0.2 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.6 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 1.2 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 1.2 GO:0035577 azurophil granule membrane(GO:0035577)
0.0 0.2 GO:0000124 SAGA complex(GO:0000124)
0.0 0.1 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 0.2 GO:0032426 stereocilium tip(GO:0032426)
0.0 0.5 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.3 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.1 GO:0005791 rough endoplasmic reticulum(GO:0005791)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0015117 thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131)
0.1 0.4 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069) L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.1 1.1 GO:0019763 immunoglobulin receptor activity(GO:0019763)
0.1 1.0 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.1 0.4 GO:0004676 3-phosphoinositide-dependent protein kinase activity(GO:0004676)
0.1 0.4 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177)
0.1 1.8 GO:0016018 cyclosporin A binding(GO:0016018)
0.1 0.4 GO:0015091 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.1 1.2 GO:0015266 protein channel activity(GO:0015266)
0.1 0.4 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.1 3.3 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.1 0.7 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.1 0.2 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.1 0.2 GO:0071885 N-terminal protein N-methyltransferase activity(GO:0071885)
0.1 0.4 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.1 0.5 GO:0043559 insulin binding(GO:0043559)
0.1 0.2 GO:0003881 CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity(GO:0003881)
0.1 1.6 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.1 0.2 GO:1990254 keratin filament binding(GO:1990254)
0.1 0.9 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.1 0.4 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.1 0.3 GO:0070815 peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.0 0.3 GO:0034511 U3 snoRNA binding(GO:0034511)
0.0 0.1 GO:0002134 pyrimidine nucleoside binding(GO:0001884) UTP binding(GO:0002134) pyrimidine ribonucleoside binding(GO:0032551)
0.0 0.2 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 0.3 GO:0051373 FATZ binding(GO:0051373)
0.0 0.2 GO:0004359 glutaminase activity(GO:0004359)
0.0 0.3 GO:0052851 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.0 0.3 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.4 GO:0034485 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485)
0.0 0.2 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
0.0 0.1 GO:0004174 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.0 0.1 GO:0004127 cytidylate kinase activity(GO:0004127)
0.0 1.3 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.5 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.2 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.0 0.4 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.7 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.1 GO:0004052 arachidonate 12-lipoxygenase activity(GO:0004052)
0.0 0.1 GO:0015141 succinate transmembrane transporter activity(GO:0015141)
0.0 0.2 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0 0.4 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.1 GO:0009383 rRNA (cytosine-C5-)-methyltransferase activity(GO:0009383)
0.0 0.1 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.0 0.6 GO:0004017 adenylate kinase activity(GO:0004017)
0.0 0.5 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.1 GO:0098770 FBXO family protein binding(GO:0098770)
0.0 0.1 GO:0045155 electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity(GO:0045155)
0.0 0.2 GO:0035473 lipase binding(GO:0035473)
0.0 0.2 GO:0005000 vasopressin receptor activity(GO:0005000)
0.0 0.2 GO:0001727 lipid kinase activity(GO:0001727)
0.0 0.3 GO:0004985 opioid receptor activity(GO:0004985)
0.0 1.6 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.1 GO:0015616 DNA translocase activity(GO:0015616)
0.0 0.1 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.0 0.2 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.0 0.2 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.1 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
0.0 0.1 GO:0017057 glucose-6-phosphate dehydrogenase activity(GO:0004345) 6-phosphogluconolactonase activity(GO:0017057)
0.0 0.1 GO:0032184 SUMO polymer binding(GO:0032184)
0.0 0.8 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.1 GO:0017129 triglyceride binding(GO:0017129)
0.0 0.1 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
0.0 0.1 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 0.1 GO:0016822 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.0 0.2 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 0.3 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.3 GO:0008097 5S rRNA binding(GO:0008097)
0.0 0.3 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.1 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.0 0.4 GO:0050786 RAGE receptor binding(GO:0050786)
0.0 0.1 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.1 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.1 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 0.2 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.0 0.7 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.4 GO:0001056 RNA polymerase III activity(GO:0001056)
0.0 0.1 GO:0000298 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848)
0.0 0.1 GO:0005237 inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.0 0.6 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 1.4 GO:0019003 GDP binding(GO:0019003)
0.0 0.5 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.4 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.2 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.0 0.5 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.1 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.0 GO:0033867 Fas-activated serine/threonine kinase activity(GO:0033867)
0.0 0.0 GO:0004967 glucagon receptor activity(GO:0004967)
0.0 0.2 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.0 GO:0004774 succinate-CoA ligase activity(GO:0004774) succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.0 0.2 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.0 0.1 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.3 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.4 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.7 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.1 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.0 0.0 GO:0019961 interferon binding(GO:0019961)
0.0 0.2 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.2 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.2 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.3 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.4 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.1 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.0 0.2 GO:0031402 sodium:potassium-exchanging ATPase activity(GO:0005391) sodium ion binding(GO:0031402)
0.0 1.8 GO:0051082 unfolded protein binding(GO:0051082)
0.0 0.1 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.3 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.2 GO:0015377 cation:chloride symporter activity(GO:0015377)
0.0 0.1 GO:0099602 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.0 0.2 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0 0.4 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.1 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.0 0.1 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.0 0.1 GO:0008318 protein prenyltransferase activity(GO:0008318)
0.0 0.1 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 ST_PAC1_RECEPTOR_PATHWAY PAC1 Receptor Pathway
0.0 0.1 PID_TCR_RAS_PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.8 ST_GAQ_PATHWAY G alpha q Pathway
0.0 0.3 ST_GRANULE_CELL_SURVIVAL_PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 0.4 PID_IL2_PI3K_PATHWAY IL2 signaling events mediated by PI3K
0.0 1.2 PID_IL4_2PATHWAY IL4-mediated signaling events
0.0 1.3 PID_REG_GR_PATHWAY Glucocorticoid receptor regulatory network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.8 REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.1 0.4 REACTOME_TRANSFERRIN_ENDOCYTOSIS_AND_RECYCLING Genes involved in Transferrin endocytosis and recycling
0.0 1.2 REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.0 REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_GLUCAGON_LIKE_PEPTIDE1 Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.0 1.9 REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.9 REACTOME_INSULIN_RECEPTOR_RECYCLING Genes involved in Insulin receptor recycling
0.0 0.3 REACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 1.0 REACTOME_SULFUR_AMINO_ACID_METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.5 REACTOME_MTORC1_MEDIATED_SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.3 REACTOME_GLYCOPROTEIN_HORMONES Genes involved in Glycoprotein hormones
0.0 0.4 REACTOME_PLATELET_CALCIUM_HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.4 REACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.6 REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 1.5 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT Genes involved in Respiratory electron transport
0.0 0.7 REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.4 REACTOME_RNA_POL_III_CHAIN_ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.4 REACTOME_INITIAL_TRIGGERING_OF_COMPLEMENT Genes involved in Initial triggering of complement
0.0 0.4 REACTOME_REGULATORY_RNA_PATHWAYS Genes involved in Regulatory RNA pathways
0.0 0.4 REACTOME_ZINC_TRANSPORTERS Genes involved in Zinc transporters
0.0 0.3 REACTOME_DESTABILIZATION_OF_MRNA_BY_BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0 0.2 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_LATE_ENDOSOME_MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.4 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.6 REACTOME_GLYCOSPHINGOLIPID_METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.3 REACTOME_AMINO_ACID_SYNTHESIS_AND_INTERCONVERSION_TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.2 REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_PDH_COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.4 REACTOME_CD28_DEPENDENT_PI3K_AKT_SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling