Motif ID: ETV3

Z-value: 0.628


Transcription factors associated with ETV3:

Gene SymbolEntrez IDGene Name
ETV3 ENSG00000117036.7 ETV3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
ETV3hg19_v2_chr1_-_157108266_1571083470.203.4e-01Click!


Activity profile for motif ETV3.

activity profile for motif ETV3


Sorted Z-values histogram for motif ETV3

Sorted Z-values for motif ETV3



Network of associatons between targets according to the STRING database.



First level regulatory network of ETV3

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr3_+_108308513 2.926 ENST00000361582.3
DZIP3
DAZ interacting zinc finger protein 3
chr15_+_71184931 2.069 ENST00000560369.1
ENST00000260382.5
LRRC49

leucine rich repeat containing 49

chr1_+_217804661 1.950 ENST00000366933.4
SPATA17
spermatogenesis associated 17
chr15_+_71185148 1.642 ENST00000443425.2
ENST00000560755.1
LRRC49

leucine rich repeat containing 49

chr17_+_4981535 1.309 ENST00000318833.3
ZFP3
ZFP3 zinc finger protein
chr12_-_58329819 1.254 ENST00000551421.1
RP11-620J15.3
RP11-620J15.3
chr15_+_82555125 1.203 ENST00000566205.1
ENST00000339465.5
ENST00000569120.1
ENST00000566861.1
FAM154B



family with sequence similarity 154, member B



chr3_-_47324008 1.181 ENST00000425853.1
KIF9
kinesin family member 9
chr3_-_47324079 1.177 ENST00000352910.4
KIF9
kinesin family member 9
chr11_+_71791359 1.172 ENST00000419228.1
ENST00000435085.1
ENST00000307198.7
ENST00000538413.1
LRTOMT



leucine rich transmembrane and O-methyltransferase domain containing



chr1_-_169337176 1.071 ENST00000472647.1
ENST00000367811.3
NME7

NME/NM23 family member 7

chr3_-_47324242 1.062 ENST00000456548.1
ENST00000432493.1
ENST00000335044.2
ENST00000444589.2
KIF9



kinesin family member 9



chr1_+_22351977 1.057 ENST00000420503.1
ENST00000416769.1
ENST00000404210.2
LINC00339


long intergenic non-protein coding RNA 339


chr11_+_71791849 1.044 ENST00000423494.2
ENST00000539587.1
ENST00000538478.1
ENST00000324866.7
ENST00000439209.1
LRTOMT




leucine rich transmembrane and O-methyltransferase domain containing




chr17_-_19281203 1.005 ENST00000487415.2
B9D1
B9 protein domain 1
chr3_-_47324060 0.990 ENST00000452770.2
KIF9
kinesin family member 9
chr12_-_58329888 0.913 ENST00000546580.1
RP11-620J15.3
RP11-620J15.3
chr11_+_71791693 0.911 ENST00000289488.2
ENST00000447974.1
LRTOMT

leucine rich transmembrane and O-methyltransferase domain containing

chr11_+_71791803 0.898 ENST00000539271.1
LRTOMT
leucine rich transmembrane and O-methyltransferase domain containing
chr11_-_61129335 0.776 ENST00000545361.1
ENST00000539128.1
ENST00000546151.1
ENST00000447532.2
CYB561A3



cytochrome b561 family, member A3




Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 95 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 4.4 GO:0071801 regulation of podosome assembly(GO:0071801)
0.2 4.0 GO:0019614 catechol-containing compound catabolic process(GO:0019614) catecholamine catabolic process(GO:0042424)
0.0 2.5 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.3 1.3 GO:0032053 ciliary basal body organization(GO:0032053)
0.3 1.3 GO:0038108 negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108)
0.0 1.2 GO:0043101 purine-containing compound salvage(GO:0043101)
0.1 1.1 GO:0006228 UTP biosynthetic process(GO:0006228)
0.1 1.1 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 1.1 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.0 1.0 GO:0042733 embryonic digit morphogenesis(GO:0042733)
0.1 0.9 GO:0018103 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.0 0.9 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.8 GO:0016558 protein import into peroxisome matrix(GO:0016558)
0.2 0.7 GO:1901895 negative regulation of calcium-transporting ATPase activity(GO:1901895)
0.0 0.7 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.0 0.7 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.2 0.6 GO:0006174 dADP phosphorylation(GO:0006174) dGDP phosphorylation(GO:0006186) AMP phosphorylation(GO:0006756) CDP phosphorylation(GO:0061508) dAMP phosphorylation(GO:0061565) CMP phosphorylation(GO:0061566) dCMP phosphorylation(GO:0061567) GDP phosphorylation(GO:0061568) UDP phosphorylation(GO:0061569) dCDP phosphorylation(GO:0061570) TDP phosphorylation(GO:0061571)
0.1 0.6 GO:0036369 transcription factor catabolic process(GO:0036369)
0.1 0.6 GO:1901525 negative regulation of macromitophagy(GO:1901525)
0.0 0.6 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 46 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 4.2 GO:0002102 podosome(GO:0002102)
0.4 2.9 GO:0000836 Hrd1p ubiquitin ligase complex(GO:0000836)
0.1 1.3 GO:0034464 BBSome(GO:0034464)
0.2 1.2 GO:1902560 GMP reductase complex(GO:1902560)
0.1 1.0 GO:0036038 MKS complex(GO:0036038)
0.0 0.7 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 0.7 GO:0016592 mediator complex(GO:0016592)
0.1 0.6 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.1 0.6 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.0 0.6 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.6 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.1 0.5 GO:1990130 Iml1 complex(GO:1990130)
0.1 0.5 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.0 0.5 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.5 GO:0070765 gamma-secretase complex(GO:0070765)
0.0 0.5 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.5 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.1 0.4 GO:0036156 inner dynein arm(GO:0036156)
0.0 0.4 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.4 GO:0005662 DNA replication factor A complex(GO:0005662)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 64 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 4.5 GO:0003777 microtubule motor activity(GO:0003777)
0.4 4.0 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.2 2.8 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.1 1.3 GO:0034452 dynactin binding(GO:0034452)
0.2 1.2 GO:0016657 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.0 1.1 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 1.1 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.1 1.0 GO:0008158 hedgehog receptor activity(GO:0008158)
0.0 1.0 GO:0001540 beta-amyloid binding(GO:0001540)
0.2 0.7 GO:0070991 medium-chain-acyl-CoA dehydrogenase activity(GO:0070991)
0.1 0.7 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.2 0.6 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
0.1 0.6 GO:0050145 nucleoside phosphate kinase activity(GO:0050145)
0.1 0.6 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.6 GO:0000030 mannosyltransferase activity(GO:0000030)
0.1 0.5 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.0 0.5 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.5 GO:0070566 adenylyltransferase activity(GO:0070566)
0.1 0.4 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.0 0.4 GO:0004689 phosphorylase kinase activity(GO:0004689)

Gene overrepresentation in C2:CP category:

Showing 1 to 4 of 4 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.7 PID_AR_TF_PATHWAY Regulation of Androgen receptor activity
0.0 0.7 PID_SYNDECAN_3_PATHWAY Syndecan-3-mediated signaling events
0.0 0.6 PID_P38_MK2_PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.4 PID_ARF_3PATHWAY Arf1 pathway

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 15 of 15 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 4.1 REACTOME_KINESINS Genes involved in Kinesins
0.0 1.2 REACTOME_PURINE_SALVAGE Genes involved in Purine salvage
0.0 1.1 REACTOME_CGMP_EFFECTS Genes involved in cGMP effects
0.0 0.7 REACTOME_SIGNALING_BY_NOTCH4 Genes involved in Signaling by NOTCH4
0.0 0.7 REACTOME_SYNTHESIS_OF_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.6 REACTOME_REGULATION_OF_RHEB_GTPASE_ACTIVITY_BY_AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.4 REACTOME_MEMBRANE_BINDING_AND_TARGETTING_OF_GAG_PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.4 REACTOME_REMOVAL_OF_THE_FLAP_INTERMEDIATE_FROM_THE_C_STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.3 REACTOME_BASE_FREE_SUGAR_PHOSPHATE_REMOVAL_VIA_THE_SINGLE_NUCLEOTIDE_REPLACEMENT_PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 0.3 REACTOME_GAP_JUNCTION_DEGRADATION Genes involved in Gap junction degradation
0.0 0.3 REACTOME_DOWNREGULATION_OF_ERBB2_ERBB3_SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.2 REACTOME_FORMATION_OF_TRANSCRIPTION_COUPLED_NER_TC_NER_REPAIR_COMPLEX Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.0 0.2 REACTOME_ALPHA_LINOLENIC_ACID_ALA_METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.1 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_LATE_ENDOSOME_MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.1 REACTOME_COPI_MEDIATED_TRANSPORT Genes involved in COPI Mediated Transport