Motif ID: ETV7
Z-value: 1.169
Transcription factors associated with ETV7:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| ETV7 | ENSG00000010030.9 | ETV7 |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| ETV7 | hg19_v2_chr6_-_36355513_36355578 | -0.13 | 5.4e-01 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.0 | 4.9 | GO:1904158 | axonemal central apparatus assembly(GO:1904158) |
| 0.5 | 1.5 | GO:0050760 | negative regulation of thymidylate synthase biosynthetic process(GO:0050760) |
| 0.4 | 2.2 | GO:0019303 | D-ribose catabolic process(GO:0019303) |
| 0.3 | 1.0 | GO:0002071 | glandular epithelial cell maturation(GO:0002071) type B pancreatic cell maturation(GO:0072560) |
| 0.3 | 1.3 | GO:0046909 | intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445) |
| 0.3 | 1.4 | GO:0035936 | testosterone secretion(GO:0035936) regulation of testosterone secretion(GO:2000843) positive regulation of testosterone secretion(GO:2000845) |
| 0.3 | 1.6 | GO:0097327 | response to antineoplastic agent(GO:0097327) |
| 0.2 | 1.5 | GO:0006651 | diacylglycerol biosynthetic process(GO:0006651) |
| 0.2 | 1.5 | GO:0045079 | negative regulation of chemokine biosynthetic process(GO:0045079) |
| 0.2 | 7.5 | GO:0071801 | regulation of podosome assembly(GO:0071801) |
| 0.2 | 1.7 | GO:1902412 | regulation of mitotic cytokinesis(GO:1902412) |
| 0.2 | 0.9 | GO:2000255 | negative regulation of male germ cell proliferation(GO:2000255) |
| 0.2 | 0.7 | GO:0032053 | ciliary basal body organization(GO:0032053) |
| 0.2 | 0.7 | GO:0072658 | maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827) |
| 0.2 | 1.1 | GO:0034154 | toll-like receptor 7 signaling pathway(GO:0034154) |
| 0.2 | 1.1 | GO:0060040 | retinal bipolar neuron differentiation(GO:0060040) |
| 0.2 | 4.1 | GO:0019800 | peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800) |
| 0.2 | 3.8 | GO:0002523 | leukocyte migration involved in inflammatory response(GO:0002523) |
| 0.2 | 1.0 | GO:0051661 | maintenance of centrosome location(GO:0051661) |
| 0.2 | 0.8 | GO:0000973 | posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973) |
| 0.2 | 2.8 | GO:0010826 | negative regulation of centrosome duplication(GO:0010826) |
| 0.2 | 0.5 | GO:1900108 | negative regulation of nodal signaling pathway(GO:1900108) |
| 0.2 | 0.8 | GO:0006382 | adenosine to inosine editing(GO:0006382) |
| 0.1 | 1.9 | GO:0006228 | UTP biosynthetic process(GO:0006228) |
| 0.1 | 0.4 | GO:0042489 | negative regulation of odontogenesis of dentin-containing tooth(GO:0042489) |
| 0.1 | 0.7 | GO:0019276 | UDP-N-acetylgalactosamine metabolic process(GO:0019276) |
| 0.1 | 0.5 | GO:0044501 | modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032) |
| 0.1 | 0.4 | GO:1905246 | regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246) |
| 0.1 | 1.6 | GO:1902260 | negative regulation of delayed rectifier potassium channel activity(GO:1902260) |
| 0.1 | 0.7 | GO:0001712 | ectodermal cell fate commitment(GO:0001712) |
| 0.1 | 1.2 | GO:0007144 | female meiosis I(GO:0007144) |
| 0.1 | 0.7 | GO:0061737 | leukotriene signaling pathway(GO:0061737) |
| 0.1 | 2.1 | GO:0036158 | outer dynein arm assembly(GO:0036158) |
| 0.1 | 0.6 | GO:0046985 | positive regulation of hemoglobin biosynthetic process(GO:0046985) |
| 0.1 | 0.6 | GO:0032815 | negative regulation of natural killer cell activation(GO:0032815) |
| 0.1 | 0.3 | GO:0002949 | tRNA threonylcarbamoyladenosine modification(GO:0002949) |
| 0.1 | 1.3 | GO:0030854 | positive regulation of granulocyte differentiation(GO:0030854) |
| 0.1 | 2.9 | GO:0034205 | beta-amyloid formation(GO:0034205) |
| 0.1 | 0.6 | GO:0001692 | histamine metabolic process(GO:0001692) |
| 0.1 | 0.5 | GO:0030538 | embryonic genitalia morphogenesis(GO:0030538) embryonic hindgut morphogenesis(GO:0048619) |
| 0.1 | 0.7 | GO:0046599 | floor plate development(GO:0033504) regulation of centriole replication(GO:0046599) |
| 0.1 | 0.6 | GO:0052055 | modulation by symbiont of host molecular function(GO:0052055) modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422) |
| 0.1 | 0.1 | GO:0031990 | mRNA export from nucleus in response to heat stress(GO:0031990) |
| 0.1 | 0.8 | GO:0051013 | microtubule severing(GO:0051013) |
| 0.1 | 0.3 | GO:0034970 | histone H3-R2 methylation(GO:0034970) |
| 0.1 | 0.4 | GO:0046952 | ketone body catabolic process(GO:0046952) |
| 0.1 | 0.2 | GO:0002101 | tRNA wobble cytosine modification(GO:0002101) |
| 0.1 | 0.3 | GO:0033277 | abortive mitotic cell cycle(GO:0033277) |
| 0.1 | 0.8 | GO:0035754 | B cell chemotaxis(GO:0035754) |
| 0.1 | 0.7 | GO:0098532 | histone H3-K27 trimethylation(GO:0098532) |
| 0.1 | 0.2 | GO:0038109 | response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109) |
| 0.1 | 2.2 | GO:0034389 | lipid particle organization(GO:0034389) |
| 0.1 | 0.2 | GO:0002277 | myeloid dendritic cell activation involved in immune response(GO:0002277) |
| 0.1 | 0.1 | GO:0045002 | double-strand break repair via single-strand annealing(GO:0045002) |
| 0.1 | 0.2 | GO:0006425 | glutaminyl-tRNA aminoacylation(GO:0006425) |
| 0.1 | 0.6 | GO:0061470 | T follicular helper cell differentiation(GO:0061470) |
| 0.1 | 0.6 | GO:0061002 | negative regulation of dendritic spine morphogenesis(GO:0061002) |
| 0.1 | 4.0 | GO:0006458 | 'de novo' protein folding(GO:0006458) |
| 0.1 | 0.6 | GO:0015793 | glycerol transport(GO:0015793) |
| 0.1 | 0.6 | GO:0051388 | positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388) |
| 0.1 | 0.4 | GO:1901668 | regulation of superoxide dismutase activity(GO:1901668) |
| 0.1 | 0.4 | GO:0035511 | oxidative DNA demethylation(GO:0035511) |
| 0.1 | 0.2 | GO:0032484 | Ral protein signal transduction(GO:0032484) regulation of Ral protein signal transduction(GO:0032485) |
| 0.1 | 0.3 | GO:0035166 | pyrimidine dimer repair by nucleotide-excision repair(GO:0000720) post-embryonic hemopoiesis(GO:0035166) |
| 0.1 | 0.4 | GO:0000727 | double-strand break repair via break-induced replication(GO:0000727) |
| 0.1 | 2.4 | GO:0071431 | tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431) |
| 0.0 | 0.1 | GO:0044205 | 'de novo' UMP biosynthetic process(GO:0044205) |
| 0.0 | 1.6 | GO:0071157 | negative regulation of cell cycle arrest(GO:0071157) |
| 0.0 | 1.9 | GO:0001580 | detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580) |
| 0.0 | 0.1 | GO:2000583 | regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000583) negative regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000584) |
| 0.0 | 0.3 | GO:0007406 | negative regulation of neuroblast proliferation(GO:0007406) |
| 0.0 | 0.3 | GO:0070197 | meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240) |
| 0.0 | 0.3 | GO:0045629 | negative regulation of T-helper 2 cell differentiation(GO:0045629) |
| 0.0 | 0.3 | GO:0055129 | L-proline biosynthetic process(GO:0055129) |
| 0.0 | 0.7 | GO:2000480 | negative regulation of cAMP-dependent protein kinase activity(GO:2000480) |
| 0.0 | 0.4 | GO:0051611 | negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612) |
| 0.0 | 0.2 | GO:0032483 | regulation of Rab protein signal transduction(GO:0032483) |
| 0.0 | 0.1 | GO:0021823 | cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836) |
| 0.0 | 0.1 | GO:0071934 | thiamine transmembrane transport(GO:0071934) |
| 0.0 | 0.5 | GO:0035721 | intraciliary retrograde transport(GO:0035721) |
| 0.0 | 0.1 | GO:2000521 | negative regulation of immunological synapse formation(GO:2000521) |
| 0.0 | 0.4 | GO:0001887 | selenium compound metabolic process(GO:0001887) |
| 0.0 | 0.6 | GO:0032988 | ribonucleoprotein complex disassembly(GO:0032988) |
| 0.0 | 0.5 | GO:0060155 | platelet dense granule organization(GO:0060155) |
| 0.0 | 0.1 | GO:0000454 | snoRNA guided rRNA pseudouridine synthesis(GO:0000454) |
| 0.0 | 0.2 | GO:0018101 | protein citrullination(GO:0018101) histone citrullination(GO:0036414) |
| 0.0 | 0.4 | GO:0046951 | cellular ketone body metabolic process(GO:0046950) ketone body biosynthetic process(GO:0046951) |
| 0.0 | 0.3 | GO:0046826 | negative regulation of protein export from nucleus(GO:0046826) |
| 0.0 | 0.2 | GO:0001824 | blastocyst development(GO:0001824) |
| 0.0 | 2.1 | GO:0001510 | RNA methylation(GO:0001510) |
| 0.0 | 0.2 | GO:0051970 | negative regulation of transmission of nerve impulse(GO:0051970) |
| 0.0 | 0.4 | GO:0050774 | negative regulation of dendrite morphogenesis(GO:0050774) |
| 0.0 | 0.2 | GO:0070127 | tRNA aminoacylation for mitochondrial protein translation(GO:0070127) |
| 0.0 | 0.1 | GO:0006433 | prolyl-tRNA aminoacylation(GO:0006433) |
| 0.0 | 0.1 | GO:0072425 | signal transduction involved in G2 DNA damage checkpoint(GO:0072425) signal transduction involved in mitotic G2 DNA damage checkpoint(GO:0072434) |
| 0.0 | 0.1 | GO:1903281 | positive regulation of calcium:sodium antiporter activity(GO:1903281) |
| 0.0 | 0.2 | GO:0070389 | chaperone cofactor-dependent protein refolding(GO:0070389) |
| 0.0 | 0.3 | GO:2000427 | positive regulation of apoptotic cell clearance(GO:2000427) |
| 0.0 | 0.7 | GO:0000729 | DNA double-strand break processing(GO:0000729) |
| 0.0 | 0.2 | GO:0034551 | respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033) |
| 0.0 | 0.1 | GO:0006422 | aspartyl-tRNA aminoacylation(GO:0006422) |
| 0.0 | 0.4 | GO:0006610 | ribosomal protein import into nucleus(GO:0006610) |
| 0.0 | 0.8 | GO:0035735 | intraciliary transport involved in cilium morphogenesis(GO:0035735) |
| 0.0 | 1.9 | GO:0070936 | protein K48-linked ubiquitination(GO:0070936) |
| 0.0 | 1.8 | GO:0042733 | embryonic digit morphogenesis(GO:0042733) |
| 0.0 | 0.1 | GO:0043983 | histone H4-K12 acetylation(GO:0043983) |
| 0.0 | 0.4 | GO:0071850 | mitotic cell cycle arrest(GO:0071850) |
| 0.0 | 0.2 | GO:0035092 | sperm chromatin condensation(GO:0035092) |
| 0.0 | 0.1 | GO:0006556 | S-adenosylmethionine biosynthetic process(GO:0006556) |
| 0.0 | 0.5 | GO:0006123 | mitochondrial electron transport, cytochrome c to oxygen(GO:0006123) |
| 0.0 | 0.2 | GO:0048505 | regulation of development, heterochronic(GO:0040034) regulation of timing of cell differentiation(GO:0048505) |
| 0.0 | 1.3 | GO:0048791 | calcium ion-regulated exocytosis of neurotransmitter(GO:0048791) |
| 0.0 | 0.2 | GO:0010571 | positive regulation of nuclear cell cycle DNA replication(GO:0010571) |
| 0.0 | 0.1 | GO:0006880 | intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577) |
| 0.0 | 0.9 | GO:0000413 | protein peptidyl-prolyl isomerization(GO:0000413) |
| 0.0 | 0.0 | GO:0014839 | myoblast migration involved in skeletal muscle regeneration(GO:0014839) |
| 0.0 | 0.4 | GO:0007191 | adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191) |
| 0.0 | 0.3 | GO:0071688 | striated muscle myosin thick filament assembly(GO:0071688) |
| 0.0 | 0.5 | GO:0016339 | calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339) |
| 0.0 | 1.4 | GO:0006977 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977) |
| 0.0 | 1.3 | GO:0090502 | RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502) |
| 0.0 | 0.2 | GO:2000210 | positive regulation of anoikis(GO:2000210) |
| 0.0 | 0.1 | GO:0006226 | dUMP biosynthetic process(GO:0006226) |
| 0.0 | 0.2 | GO:0045008 | depyrimidination(GO:0045008) |
| 0.0 | 1.4 | GO:0030521 | androgen receptor signaling pathway(GO:0030521) |
| 0.0 | 0.3 | GO:0006293 | nucleotide-excision repair, preincision complex stabilization(GO:0006293) |
| 0.0 | 0.6 | GO:0006471 | protein ADP-ribosylation(GO:0006471) |
| 0.0 | 0.1 | GO:0060010 | Sertoli cell fate commitment(GO:0060010) |
| 0.0 | 0.2 | GO:0006622 | protein targeting to lysosome(GO:0006622) |
| 0.0 | 0.1 | GO:0072520 | seminiferous tubule development(GO:0072520) |
| 0.0 | 0.1 | GO:0051712 | positive regulation of killing of cells of other organism(GO:0051712) |
| 0.0 | 0.1 | GO:0046322 | negative regulation of fatty acid oxidation(GO:0046322) |
| 0.0 | 0.2 | GO:1901970 | positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101) |
| 0.0 | 0.2 | GO:2001224 | positive regulation of neuron migration(GO:2001224) |
| 0.0 | 0.1 | GO:0060729 | intestinal epithelial structure maintenance(GO:0060729) |
| 0.0 | 0.5 | GO:0007339 | binding of sperm to zona pellucida(GO:0007339) |
| 0.0 | 0.0 | GO:0043490 | malate-aspartate shuttle(GO:0043490) |
| 0.0 | 0.2 | GO:0044819 | mitotic G1 DNA damage checkpoint(GO:0031571) mitotic G1/S transition checkpoint(GO:0044819) |
| 0.0 | 0.1 | GO:1904424 | regulation of GTP binding(GO:1904424) |
| 0.0 | 0.3 | GO:0043949 | regulation of cAMP-mediated signaling(GO:0043949) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.5 | 3.9 | GO:0034688 | integrin alphaM-beta2 complex(GO:0034688) |
| 0.3 | 4.9 | GO:0036038 | MKS complex(GO:0036038) |
| 0.3 | 0.8 | GO:1990876 | cytoplasmic side of nuclear pore(GO:1990876) |
| 0.3 | 1.0 | GO:0036396 | MIS complex(GO:0036396) mRNA editing complex(GO:0045293) |
| 0.3 | 1.3 | GO:0005879 | axonemal microtubule(GO:0005879) |
| 0.2 | 1.4 | GO:0031262 | Ndc80 complex(GO:0031262) |
| 0.2 | 2.4 | GO:0070765 | gamma-secretase complex(GO:0070765) |
| 0.2 | 3.7 | GO:0005832 | chaperonin-containing T-complex(GO:0005832) |
| 0.2 | 1.7 | GO:0000235 | astral microtubule(GO:0000235) aster(GO:0005818) |
| 0.2 | 1.5 | GO:1990761 | growth cone lamellipodium(GO:1990761) growth cone filopodium(GO:1990812) |
| 0.1 | 0.6 | GO:0071008 | U2-type post-mRNA release spliceosomal complex(GO:0071008) |
| 0.1 | 1.4 | GO:0044615 | nuclear pore nuclear basket(GO:0044615) |
| 0.1 | 8.2 | GO:0005871 | kinesin complex(GO:0005871) |
| 0.1 | 0.3 | GO:0031372 | UBC13-MMS2 complex(GO:0031372) |
| 0.1 | 0.3 | GO:0000229 | cytoplasmic chromosome(GO:0000229) |
| 0.1 | 1.1 | GO:0036157 | outer dynein arm(GO:0036157) |
| 0.1 | 1.0 | GO:0033588 | Elongator holoenzyme complex(GO:0033588) |
| 0.1 | 0.6 | GO:0032777 | Piccolo NuA4 histone acetyltransferase complex(GO:0032777) |
| 0.1 | 0.5 | GO:0000408 | EKC/KEOPS complex(GO:0000408) |
| 0.1 | 1.1 | GO:0001673 | male germ cell nucleus(GO:0001673) |
| 0.1 | 0.7 | GO:0097504 | Gemini of coiled bodies(GO:0097504) |
| 0.1 | 0.3 | GO:0002081 | inner acrosomal membrane(GO:0002079) outer acrosomal membrane(GO:0002081) |
| 0.1 | 0.4 | GO:0043541 | UDP-N-acetylglucosamine transferase complex(GO:0043541) |
| 0.1 | 0.4 | GO:0000835 | ER ubiquitin ligase complex(GO:0000835) |
| 0.1 | 0.4 | GO:1990130 | Iml1 complex(GO:1990130) |
| 0.1 | 0.5 | GO:0030991 | intraciliary transport particle A(GO:0030991) |
| 0.0 | 0.3 | GO:0000110 | nucleotide-excision repair factor 1 complex(GO:0000110) |
| 0.0 | 5.1 | GO:0097014 | axoneme(GO:0005930) ciliary plasm(GO:0097014) |
| 0.0 | 0.3 | GO:1990393 | 3M complex(GO:1990393) |
| 0.0 | 0.1 | GO:0034687 | integrin alphaL-beta2 complex(GO:0034687) |
| 0.0 | 0.2 | GO:0098575 | lumenal side of lysosomal membrane(GO:0098575) |
| 0.0 | 0.1 | GO:1902636 | kinociliary basal body(GO:1902636) |
| 0.0 | 0.5 | GO:0097418 | neurofibrillary tangle(GO:0097418) |
| 0.0 | 0.5 | GO:0005662 | DNA replication factor A complex(GO:0005662) |
| 0.0 | 0.7 | GO:0014731 | spectrin-associated cytoskeleton(GO:0014731) |
| 0.0 | 0.3 | GO:0097486 | multivesicular body lumen(GO:0097486) |
| 0.0 | 0.2 | GO:0031313 | extrinsic component of endosome membrane(GO:0031313) |
| 0.0 | 0.9 | GO:0016581 | NuRD complex(GO:0016581) CHD-type complex(GO:0090545) |
| 0.0 | 0.3 | GO:0042105 | alpha-beta T cell receptor complex(GO:0042105) |
| 0.0 | 0.5 | GO:0008385 | IkappaB kinase complex(GO:0008385) |
| 0.0 | 0.5 | GO:0005751 | mitochondrial respiratory chain complex IV(GO:0005751) |
| 0.0 | 0.1 | GO:0035032 | phosphatidylinositol 3-kinase complex, class III(GO:0035032) |
| 0.0 | 0.1 | GO:0070939 | Dsl1p complex(GO:0070939) |
| 0.0 | 1.2 | GO:0005719 | nuclear euchromatin(GO:0005719) |
| 0.0 | 0.5 | GO:0034709 | methylosome(GO:0034709) |
| 0.0 | 0.6 | GO:0031229 | integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) |
| 0.0 | 0.4 | GO:0097225 | sperm midpiece(GO:0097225) |
| 0.0 | 0.1 | GO:0042272 | nuclear RNA export factor complex(GO:0042272) |
| 0.0 | 0.1 | GO:0048269 | methionine adenosyltransferase complex(GO:0048269) |
| 0.0 | 0.4 | GO:0005885 | Arp2/3 protein complex(GO:0005885) |
| 0.0 | 0.5 | GO:0031083 | BLOC-1 complex(GO:0031083) |
| 0.0 | 0.6 | GO:0034451 | centriolar satellite(GO:0034451) |
| 0.0 | 0.3 | GO:0031209 | SCAR complex(GO:0031209) |
| 0.0 | 0.1 | GO:0072589 | box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661) |
| 0.0 | 0.7 | GO:0080008 | Cul4-RING E3 ubiquitin ligase complex(GO:0080008) |
| 0.0 | 0.2 | GO:0032009 | early phagosome(GO:0032009) |
| 0.0 | 0.1 | GO:0030915 | Smc5-Smc6 complex(GO:0030915) |
| 0.0 | 0.3 | GO:0031265 | CD95 death-inducing signaling complex(GO:0031265) ripoptosome(GO:0097342) |
| 0.0 | 0.0 | GO:0070069 | cytochrome complex(GO:0070069) |
| 0.0 | 0.1 | GO:0090571 | RNA polymerase II transcription repressor complex(GO:0090571) |
| 0.0 | 0.2 | GO:0000439 | core TFIIH complex(GO:0000439) |
| 0.0 | 0.2 | GO:0033391 | chromatoid body(GO:0033391) |
| 0.0 | 0.2 | GO:0035102 | PRC1 complex(GO:0035102) |
| 0.0 | 0.1 | GO:0044194 | cytolytic granule(GO:0044194) |
| 0.0 | 0.7 | GO:0045171 | intercellular bridge(GO:0045171) |
| 0.0 | 0.1 | GO:0000322 | storage vacuole(GO:0000322) |
| 0.0 | 1.5 | GO:0005581 | collagen trimer(GO:0005581) |
| 0.0 | 1.7 | GO:0008076 | voltage-gated potassium channel complex(GO:0008076) |
| 0.0 | 0.1 | GO:0030126 | COPI vesicle coat(GO:0030126) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.5 | 1.6 | GO:0032440 | 2-alkenal reductase [NAD(P)] activity(GO:0032440) |
| 0.4 | 1.7 | GO:0009019 | tRNA (guanine-N1-)-methyltransferase activity(GO:0009019) |
| 0.4 | 4.0 | GO:0030369 | ICAM-3 receptor activity(GO:0030369) |
| 0.3 | 2.3 | GO:0004522 | ribonuclease A activity(GO:0004522) |
| 0.3 | 0.9 | GO:0016422 | mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422) |
| 0.3 | 2.4 | GO:0008158 | hedgehog receptor activity(GO:0008158) |
| 0.2 | 0.9 | GO:0004667 | prostaglandin-D synthase activity(GO:0004667) |
| 0.2 | 1.1 | GO:0005499 | vitamin D binding(GO:0005499) |
| 0.2 | 0.6 | GO:0005136 | interleukin-4 receptor binding(GO:0005136) |
| 0.1 | 4.1 | GO:0008191 | metalloendopeptidase inhibitor activity(GO:0008191) |
| 0.1 | 0.4 | GO:0003858 | 3-hydroxybutyrate dehydrogenase activity(GO:0003858) |
| 0.1 | 5.6 | GO:0044183 | protein binding involved in protein folding(GO:0044183) |
| 0.1 | 0.7 | GO:0047237 | glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047237) |
| 0.1 | 1.7 | GO:0001011 | transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087) |
| 0.1 | 1.0 | GO:0003956 | NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956) |
| 0.1 | 0.9 | GO:0044020 | histone methyltransferase activity (H4-R3 specific)(GO:0044020) |
| 0.1 | 0.7 | GO:0004974 | leukotriene receptor activity(GO:0004974) |
| 0.1 | 0.4 | GO:0035514 | DNA demethylase activity(GO:0035514) |
| 0.1 | 1.6 | GO:0031433 | telethonin binding(GO:0031433) |
| 0.1 | 0.6 | GO:0015254 | glycerol channel activity(GO:0015254) |
| 0.1 | 0.8 | GO:0016300 | tRNA (uracil) methyltransferase activity(GO:0016300) |
| 0.1 | 2.6 | GO:0031005 | filamin binding(GO:0031005) |
| 0.1 | 0.8 | GO:0008568 | microtubule-severing ATPase activity(GO:0008568) |
| 0.1 | 0.3 | GO:0052798 | beta-galactoside alpha-2,3-sialyltransferase activity(GO:0052798) |
| 0.1 | 1.5 | GO:0048156 | tau protein binding(GO:0048156) |
| 0.1 | 1.0 | GO:0005049 | nuclear export signal receptor activity(GO:0005049) |
| 0.1 | 0.2 | GO:0004819 | glutamine-tRNA ligase activity(GO:0004819) |
| 0.1 | 0.2 | GO:0047389 | glycerophosphocholine phosphodiesterase activity(GO:0047389) |
| 0.1 | 0.3 | GO:0022865 | transmembrane electron transfer carrier(GO:0022865) |
| 0.1 | 8.2 | GO:0003777 | microtubule motor activity(GO:0003777) |
| 0.1 | 1.9 | GO:0004550 | nucleoside diphosphate kinase activity(GO:0004550) |
| 0.1 | 2.2 | GO:0019200 | carbohydrate kinase activity(GO:0019200) |
| 0.1 | 1.3 | GO:0042043 | neurexin family protein binding(GO:0042043) |
| 0.1 | 1.1 | GO:0070513 | death domain binding(GO:0070513) |
| 0.1 | 0.9 | GO:0036312 | phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312) |
| 0.1 | 0.3 | GO:0097199 | cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199) |
| 0.1 | 1.8 | GO:0005487 | nucleocytoplasmic transporter activity(GO:0005487) |
| 0.1 | 0.2 | GO:0032090 | Pyrin domain binding(GO:0032090) |
| 0.1 | 0.3 | GO:0003987 | acetate-CoA ligase activity(GO:0003987) |
| 0.0 | 0.3 | GO:1990599 | 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599) |
| 0.0 | 0.1 | GO:0008534 | oxidized purine nucleobase lesion DNA N-glycosylase activity(GO:0008534) |
| 0.0 | 0.1 | GO:0015403 | thiamine uptake transmembrane transporter activity(GO:0015403) |
| 0.0 | 0.5 | GO:0016015 | morphogen activity(GO:0016015) |
| 0.0 | 0.3 | GO:0004735 | pyrroline-5-carboxylate reductase activity(GO:0004735) |
| 0.0 | 0.2 | GO:0000179 | rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179) |
| 0.0 | 0.4 | GO:0016846 | carbon-sulfur lyase activity(GO:0016846) |
| 0.0 | 0.4 | GO:0031681 | G-protein beta-subunit binding(GO:0031681) |
| 0.0 | 0.5 | GO:0001135 | transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135) |
| 0.0 | 1.0 | GO:0034237 | protein kinase A regulatory subunit binding(GO:0034237) |
| 0.0 | 4.5 | GO:0051082 | unfolded protein binding(GO:0051082) |
| 0.0 | 0.4 | GO:1904264 | ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264) |
| 0.0 | 0.2 | GO:0004668 | protein-arginine deiminase activity(GO:0004668) |
| 0.0 | 1.2 | GO:0004435 | phosphatidylinositol phospholipase C activity(GO:0004435) |
| 0.0 | 1.6 | GO:0031492 | nucleosomal DNA binding(GO:0031492) |
| 0.0 | 0.2 | GO:0047631 | ADP-ribose diphosphatase activity(GO:0047631) |
| 0.0 | 0.1 | GO:0047757 | chondroitin-glucuronate 5-epimerase activity(GO:0047757) |
| 0.0 | 0.1 | GO:0004132 | dCMP deaminase activity(GO:0004132) |
| 0.0 | 0.1 | GO:0004827 | proline-tRNA ligase activity(GO:0004827) |
| 0.0 | 0.4 | GO:0016018 | cyclosporin A binding(GO:0016018) |
| 0.0 | 0.7 | GO:0004862 | cAMP-dependent protein kinase inhibitor activity(GO:0004862) |
| 0.0 | 0.3 | GO:0015377 | cation:chloride symporter activity(GO:0015377) |
| 0.0 | 0.8 | GO:0030676 | Rac guanyl-nucleotide exchange factor activity(GO:0030676) |
| 0.0 | 0.2 | GO:0004844 | uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506) |
| 0.0 | 0.2 | GO:0035381 | extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381) |
| 0.0 | 0.5 | GO:0050811 | GABA receptor binding(GO:0050811) |
| 0.0 | 0.8 | GO:0008395 | steroid hydroxylase activity(GO:0008395) |
| 0.0 | 0.1 | GO:0004466 | long-chain-acyl-CoA dehydrogenase activity(GO:0004466) |
| 0.0 | 0.5 | GO:0005545 | 1-phosphatidylinositol binding(GO:0005545) |
| 0.0 | 0.1 | GO:0002046 | opsin binding(GO:0002046) |
| 0.0 | 0.9 | GO:0003755 | peptidyl-prolyl cis-trans isomerase activity(GO:0003755) |
| 0.0 | 0.2 | GO:0000774 | adenyl-nucleotide exchange factor activity(GO:0000774) |
| 0.0 | 0.8 | GO:0004198 | calcium-dependent cysteine-type endopeptidase activity(GO:0004198) |
| 0.0 | 0.7 | GO:0070273 | phosphatidylinositol-4-phosphate binding(GO:0070273) |
| 0.0 | 0.4 | GO:0031418 | L-ascorbic acid binding(GO:0031418) |
| 0.0 | 0.2 | GO:0008467 | [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467) |
| 0.0 | 0.3 | GO:0047134 | protein-disulfide reductase activity(GO:0047134) |
| 0.0 | 1.5 | GO:0005507 | copper ion binding(GO:0005507) |
| 0.0 | 0.1 | GO:0003829 | beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829) |
| 0.0 | 0.3 | GO:0034450 | ubiquitin-ubiquitin ligase activity(GO:0034450) |
| 0.0 | 0.5 | GO:0050750 | low-density lipoprotein particle receptor binding(GO:0050750) |
| 0.0 | 0.1 | GO:0001849 | complement component C1q binding(GO:0001849) |
| 0.0 | 0.3 | GO:0030306 | ADP-ribosylation factor binding(GO:0030306) |
| 0.0 | 0.2 | GO:0004030 | aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030) |
| 0.0 | 0.7 | GO:0030507 | spectrin binding(GO:0030507) |
| 0.0 | 0.3 | GO:0008320 | protein transmembrane transporter activity(GO:0008320) |
| 0.0 | 0.5 | GO:0016676 | cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676) |
| 0.0 | 0.2 | GO:0043495 | protein anchor(GO:0043495) |
| 0.0 | 0.1 | GO:0008553 | hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553) |
| 0.0 | 0.1 | GO:0004815 | aspartate-tRNA ligase activity(GO:0004815) |
| 0.0 | 0.1 | GO:0008046 | axon guidance receptor activity(GO:0008046) |
| 0.0 | 0.2 | GO:0016493 | C-C chemokine receptor activity(GO:0016493) |
| 0.0 | 0.1 | GO:0019863 | IgE binding(GO:0019863) |
| 0.0 | 0.3 | GO:0008093 | cytoskeletal adaptor activity(GO:0008093) |
| 0.0 | 0.6 | GO:0070491 | repressing transcription factor binding(GO:0070491) |
| 0.0 | 0.3 | GO:0004190 | aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001) |
| 0.0 | 0.1 | GO:0035529 | NADH pyrophosphatase activity(GO:0035529) |
| 0.0 | 0.2 | GO:0097371 | MDM2/MDM4 family protein binding(GO:0097371) |
| 0.0 | 0.3 | GO:0001077 | transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) |
| 0.0 | 0.3 | GO:0005001 | transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198) |
| 0.0 | 0.1 | GO:0034513 | box H/ACA snoRNA binding(GO:0034513) |
| 0.0 | 0.2 | GO:0001223 | transcription coactivator binding(GO:0001223) |
| 0.0 | 0.1 | GO:0016167 | glial cell-derived neurotrophic factor receptor activity(GO:0016167) |
| 0.0 | 0.4 | GO:0005035 | tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035) |
| 0.0 | 0.4 | GO:0005159 | insulin-like growth factor receptor binding(GO:0005159) |
| 0.0 | 0.1 | GO:0008199 | ferric iron binding(GO:0008199) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 3.7 | PID_INTEGRIN_CS_PATHWAY | Integrin family cell surface interactions |
| 0.1 | 4.1 | NABA_PROTEOGLYCANS | Genes encoding proteoglycans |
| 0.0 | 1.2 | PID_SYNDECAN_3_PATHWAY | Syndecan-3-mediated signaling events |
| 0.0 | 2.1 | PID_CDC42_REG_PATHWAY | Regulation of CDC42 activity |
| 0.0 | 1.6 | NABA_COLLAGENS | Genes encoding collagen proteins |
| 0.0 | 3.1 | PID_AR_PATHWAY | Coregulation of Androgen receptor activity |
| 0.0 | 0.7 | PID_ARF_3PATHWAY | Arf1 pathway |
| 0.0 | 0.6 | PID_SMAD2_3PATHWAY | Regulation of cytoplasmic and nuclear SMAD2/3 signaling |
| 0.0 | 0.4 | PID_THROMBIN_PAR4_PATHWAY | PAR4-mediated thrombin signaling events |
| 0.0 | 0.7 | PID_HEDGEHOG_2PATHWAY | Signaling events mediated by the Hedgehog family |
| 0.0 | 0.6 | ST_MYOCYTE_AD_PATHWAY | Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway. |
| 0.0 | 1.1 | PID_RAS_PATHWAY | Regulation of Ras family activation |
| 0.0 | 1.0 | PID_CERAMIDE_PATHWAY | Ceramide signaling pathway |
| 0.0 | 0.9 | PID_ENDOTHELIN_PATHWAY | Endothelins |
| 0.0 | 1.3 | PID_FCER1_PATHWAY | Fc-epsilon receptor I signaling in mast cells |
| 0.0 | 0.5 | PID_HNF3B_PATHWAY | FOXA2 and FOXA3 transcription factor networks |
| 0.0 | 1.1 | PID_ERA_GENOMIC_PATHWAY | Validated nuclear estrogen receptor alpha network |
| 0.0 | 0.3 | PID_EPO_PATHWAY | EPO signaling pathway |
| 0.0 | 0.4 | PID_INSULIN_GLUCOSE_PATHWAY | Insulin-mediated glucose transport |
| 0.0 | 0.6 | PID_ECADHERIN_STABILIZATION_PATHWAY | Stabilization and expansion of the E-cadherin adherens junction |
| 0.0 | 0.5 | PID_FRA_PATHWAY | Validated transcriptional targets of AP1 family members Fra1 and Fra2 |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 7.7 | REACTOME_KINESINS | Genes involved in Kinesins |
| 0.1 | 2.4 | REACTOME_SIGNALING_BY_NOTCH4 | Genes involved in Signaling by NOTCH4 |
| 0.0 | 2.2 | REACTOME_NEP_NS2_INTERACTS_WITH_THE_CELLULAR_EXPORT_MACHINERY | Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery |
| 0.0 | 0.6 | REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS | Genes involved in Passive Transport by Aquaporins |
| 0.0 | 0.7 | REACTOME_EICOSANOID_LIGAND_BINDING_RECEPTORS | Genes involved in Eicosanoid ligand-binding receptors |
| 0.0 | 0.7 | REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION | Genes involved in Apoptosis induced DNA fragmentation |
| 0.0 | 0.8 | REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS | Genes involved in Synthesis of bile acids and bile salts |
| 0.0 | 1.7 | REACTOME_MYOGENESIS | Genes involved in Myogenesis |
| 0.0 | 0.9 | REACTOME_G0_AND_EARLY_G1 | Genes involved in G0 and Early G1 |
| 0.0 | 3.2 | REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL | Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell |
| 0.0 | 0.7 | REACTOME_METABOLISM_OF_NON_CODING_RNA | Genes involved in Metabolism of non-coding RNA |
| 0.0 | 0.7 | REACTOME_FORMATION_OF_INCISION_COMPLEX_IN_GG_NER | Genes involved in Formation of incision complex in GG-NER |
| 0.0 | 0.7 | REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS | Genes involved in Termination of O-glycan biosynthesis |
| 0.0 | 0.5 | REACTOME_RAS_ACTIVATION_UOPN_CA2_INFUX_THROUGH_NMDA_RECEPTOR | Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor |
| 0.0 | 0.4 | REACTOME_THE_NLRP3_INFLAMMASOME | Genes involved in The NLRP3 inflammasome |
| 0.0 | 0.7 | REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS | Genes involved in Interaction between L1 and Ankyrins |
| 0.0 | 0.7 | REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS | Genes involved in Caspase-mediated cleavage of cytoskeletal proteins |
| 0.0 | 1.3 | REACTOME_COLLAGEN_FORMATION | Genes involved in Collagen formation |
| 0.0 | 0.2 | REACTOME_SIGNAL_ATTENUATION | Genes involved in Signal attenuation |
| 0.0 | 0.4 | REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PLC_BETA | Genes involved in G beta:gamma signalling through PLC beta |
| 0.0 | 0.3 | REACTOME_OTHER_SEMAPHORIN_INTERACTIONS | Genes involved in Other semaphorin interactions |
| 0.0 | 0.2 | REACTOME_TRAFFICKING_AND_PROCESSING_OF_ENDOSOMAL_TLR | Genes involved in Trafficking and processing of endosomal TLR |
| 0.0 | 0.5 | REACTOME_DEADENYLATION_OF_MRNA | Genes involved in Deadenylation of mRNA |
| 0.0 | 0.4 | REACTOME_GABA_A_RECEPTOR_ACTIVATION | Genes involved in GABA A receptor activation |
| 0.0 | 0.3 | REACTOME_PD1_SIGNALING | Genes involved in PD-1 signaling |
| 0.0 | 0.4 | REACTOME_ACTIVATION_OF_THE_PRE_REPLICATIVE_COMPLEX | Genes involved in Activation of the pre-replicative complex |
