Motif ID: ETV7

Z-value: 1.169


Transcription factors associated with ETV7:

Gene SymbolEntrez IDGene Name
ETV7 ENSG00000010030.9 ETV7

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
ETV7hg19_v2_chr6_-_36355513_36355578-0.135.4e-01Click!


Activity profile for motif ETV7.

activity profile for motif ETV7


Sorted Z-values histogram for motif ETV7

Sorted Z-values for motif ETV7



Network of associatons between targets according to the STRING database.



First level regulatory network of ETV7

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr17_+_9479944 3.185 ENST00000396219.3
ENST00000352665.5
WDR16

WD repeat domain 16

chr3_-_19988462 3.116 ENST00000344838.4
EFHB
EF-hand domain family, member B
chr3_+_63638339 2.960 ENST00000343837.3
ENST00000469440.1
SNTN

sentan, cilia apical structure protein

chr11_+_61976137 2.611 ENST00000244930.4
SCGB2A1
secretoglobin, family 2A, member 1
chr12_-_58329819 2.557 ENST00000551421.1
RP11-620J15.3
RP11-620J15.3
chr21_-_46340770 2.500 ENST00000397854.3
ITGB2
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr11_+_73676281 2.497 ENST00000543947.1
DNAJB13
DnaJ (Hsp40) homolog, subfamily B, member 13
chr17_-_19281203 2.364 ENST00000487415.2
B9D1
B9 protein domain 1
chr11_+_73675873 2.355 ENST00000537753.1
ENST00000542350.1
DNAJB13

DnaJ (Hsp40) homolog, subfamily B, member 13

chr14_-_21270561 2.314 ENST00000412779.2
RNASE1
ribonuclease, RNase A family, 1 (pancreatic)
chr3_-_47324242 2.300 ENST00000456548.1
ENST00000432493.1
ENST00000335044.2
ENST00000444589.2
KIF9



kinesin family member 9



chr2_-_28113965 2.245 ENST00000302188.3
RBKS
ribokinase
chr3_-_47324079 2.089 ENST00000352910.4
KIF9
kinesin family member 9
chr1_-_169337176 1.943 ENST00000472647.1
ENST00000367811.3
NME7

NME/NM23 family member 7

chr7_-_99569468 1.943 ENST00000419575.1
AZGP1
alpha-2-glycoprotein 1, zinc-binding
chr12_-_58329888 1.836 ENST00000546580.1
RP11-620J15.3
RP11-620J15.3
chr3_-_47324008 1.831 ENST00000425853.1
KIF9
kinesin family member 9
chr21_-_46340884 1.801 ENST00000302347.5
ENST00000517819.1
ITGB2

integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)

chrX_-_80457385 1.618 ENST00000451455.1
ENST00000436386.1
ENST00000358130.2
HMGN5


high mobility group nucleosome binding domain 5


chr6_-_56258892 1.608 ENST00000370819.1
COL21A1
collagen, type XXI, alpha 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 140 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 7.5 GO:0071801 regulation of podosome assembly(GO:0071801)
1.0 4.9 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.2 4.1 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.1 4.0 GO:0006458 'de novo' protein folding(GO:0006458)
0.2 3.8 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.1 2.9 GO:0034205 beta-amyloid formation(GO:0034205)
0.2 2.8 GO:0010826 negative regulation of centrosome duplication(GO:0010826)
0.1 2.4 GO:0071431 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.4 2.2 GO:0019303 D-ribose catabolic process(GO:0019303)
0.1 2.2 GO:0034389 lipid particle organization(GO:0034389)
0.1 2.1 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 2.1 GO:0001510 RNA methylation(GO:0001510)
0.1 1.9 GO:0006228 UTP biosynthetic process(GO:0006228)
0.0 1.9 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 1.9 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.0 1.8 GO:0042733 embryonic digit morphogenesis(GO:0042733)
0.2 1.7 GO:1902412 regulation of mitotic cytokinesis(GO:1902412)
0.3 1.6 GO:0097327 response to antineoplastic agent(GO:0097327)
0.1 1.6 GO:1902260 negative regulation of delayed rectifier potassium channel activity(GO:1902260)
0.0 1.6 GO:0071157 negative regulation of cell cycle arrest(GO:0071157)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 69 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 8.2 GO:0005871 kinesin complex(GO:0005871)
0.0 5.1 GO:0097014 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.3 4.9 GO:0036038 MKS complex(GO:0036038)
0.5 3.9 GO:0034688 integrin alphaM-beta2 complex(GO:0034688)
0.2 3.7 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.2 2.4 GO:0070765 gamma-secretase complex(GO:0070765)
0.2 1.7 GO:0000235 astral microtubule(GO:0000235) aster(GO:0005818)
0.0 1.7 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.2 1.5 GO:1990761 growth cone lamellipodium(GO:1990761) growth cone filopodium(GO:1990812)
0.0 1.5 GO:0005581 collagen trimer(GO:0005581)
0.2 1.4 GO:0031262 Ndc80 complex(GO:0031262)
0.1 1.4 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.3 1.3 GO:0005879 axonemal microtubule(GO:0005879)
0.0 1.2 GO:0005719 nuclear euchromatin(GO:0005719)
0.1 1.1 GO:0036157 outer dynein arm(GO:0036157)
0.1 1.1 GO:0001673 male germ cell nucleus(GO:0001673)
0.3 1.0 GO:0036396 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.1 1.0 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.9 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.3 0.8 GO:1990876 cytoplasmic side of nuclear pore(GO:1990876)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 105 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 8.2 GO:0003777 microtubule motor activity(GO:0003777)
0.1 5.6 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 4.5 GO:0051082 unfolded protein binding(GO:0051082)
0.1 4.1 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.4 4.0 GO:0030369 ICAM-3 receptor activity(GO:0030369)
0.1 2.6 GO:0031005 filamin binding(GO:0031005)
0.3 2.4 GO:0008158 hedgehog receptor activity(GO:0008158)
0.3 2.3 GO:0004522 ribonuclease A activity(GO:0004522)
0.1 2.2 GO:0019200 carbohydrate kinase activity(GO:0019200)
0.1 1.9 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.1 1.8 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.4 1.7 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.1 1.7 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.5 1.6 GO:0032440 2-alkenal reductase [NAD(P)] activity(GO:0032440)
0.1 1.6 GO:0031433 telethonin binding(GO:0031433)
0.0 1.6 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.1 1.5 GO:0048156 tau protein binding(GO:0048156)
0.0 1.5 GO:0005507 copper ion binding(GO:0005507)
0.1 1.3 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 1.2 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)

Gene overrepresentation in C2:CP category:

Showing 1 to 20 of 21 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 4.1 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.1 3.7 PID_INTEGRIN_CS_PATHWAY Integrin family cell surface interactions
0.0 3.1 PID_AR_PATHWAY Coregulation of Androgen receptor activity
0.0 2.1 PID_CDC42_REG_PATHWAY Regulation of CDC42 activity
0.0 1.6 NABA_COLLAGENS Genes encoding collagen proteins
0.0 1.3 PID_FCER1_PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 1.2 PID_SYNDECAN_3_PATHWAY Syndecan-3-mediated signaling events
0.0 1.1 PID_RAS_PATHWAY Regulation of Ras family activation
0.0 1.1 PID_ERA_GENOMIC_PATHWAY Validated nuclear estrogen receptor alpha network
0.0 1.0 PID_CERAMIDE_PATHWAY Ceramide signaling pathway
0.0 0.9 PID_ENDOTHELIN_PATHWAY Endothelins
0.0 0.7 PID_ARF_3PATHWAY Arf1 pathway
0.0 0.7 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.6 PID_SMAD2_3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.6 ST_MYOCYTE_AD_PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 0.6 PID_ECADHERIN_STABILIZATION_PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.5 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.5 PID_FRA_PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.4 PID_THROMBIN_PAR4_PATHWAY PAR4-mediated thrombin signaling events
0.0 0.4 PID_INSULIN_GLUCOSE_PATHWAY Insulin-mediated glucose transport

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 20 of 26 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 7.7 REACTOME_KINESINS Genes involved in Kinesins
0.0 3.2 REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1 2.4 REACTOME_SIGNALING_BY_NOTCH4 Genes involved in Signaling by NOTCH4
0.0 2.2 REACTOME_NEP_NS2_INTERACTS_WITH_THE_CELLULAR_EXPORT_MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0 1.7 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.0 1.3 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.0 0.9 REACTOME_G0_AND_EARLY_G1 Genes involved in G0 and Early G1
0.0 0.8 REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS Genes involved in Synthesis of bile acids and bile salts
0.0 0.7 REACTOME_EICOSANOID_LIGAND_BINDING_RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.0 0.7 REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.7 REACTOME_METABOLISM_OF_NON_CODING_RNA Genes involved in Metabolism of non-coding RNA
0.0 0.7 REACTOME_FORMATION_OF_INCISION_COMPLEX_IN_GG_NER Genes involved in Formation of incision complex in GG-NER
0.0 0.7 REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.7 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.7 REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.6 REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.5 REACTOME_RAS_ACTIVATION_UOPN_CA2_INFUX_THROUGH_NMDA_RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0 0.5 REACTOME_DEADENYLATION_OF_MRNA Genes involved in Deadenylation of mRNA
0.0 0.4 REACTOME_THE_NLRP3_INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.4 REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PLC_BETA Genes involved in G beta:gamma signalling through PLC beta