Motif ID: EZH2

Z-value: 1.316


Transcription factors associated with EZH2:

Gene SymbolEntrez IDGene Name
EZH2 ENSG00000106462.6 EZH2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
EZH2hg19_v2_chr7_-_148581251_148581347-0.501.2e-02Click!


Activity profile for motif EZH2.

activity profile for motif EZH2


Sorted Z-values histogram for motif EZH2

Sorted Z-values for motif EZH2



Network of associatons between targets according to the STRING database.



First level regulatory network of EZH2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_-_41740181 2.187 ENST00000442711.1
INHBA
inhibin, beta A
chr1_-_205391178 2.164 ENST00000367153.4
ENST00000367151.2
ENST00000391936.2
ENST00000367149.3
LEMD1



LEM domain containing 1



chr8_-_7274385 1.978 ENST00000318157.2
DEFB4B
defensin, beta 4B
chr1_-_145076186 1.816 ENST00000369348.3
PDE4DIP
phosphodiesterase 4D interacting protein
chr19_-_51504852 1.748 ENST00000391806.2
ENST00000347619.4
ENST00000291726.7
ENST00000320838.5
KLK8



kallikrein-related peptidase 8



chr12_-_91576561 1.699 ENST00000547568.2
ENST00000552962.1
DCN

decorin

chr19_+_51152702 1.575 ENST00000425202.1
C19orf81
chromosome 19 open reading frame 81
chr1_+_152881014 1.508 ENST00000368764.3
ENST00000392667.2
IVL

involucrin

chr13_-_20805109 1.476 ENST00000241124.6
GJB6
gap junction protein, beta 6, 30kDa
chr5_+_92919043 1.436 ENST00000327111.3
NR2F1
nuclear receptor subfamily 2, group F, member 1
chr7_+_145813453 1.376 ENST00000361727.3
CNTNAP2
contactin associated protein-like 2
chr3_-_195538728 1.345 ENST00000349607.4
ENST00000346145.4
MUC4

mucin 4, cell surface associated

chr11_-_66496430 1.338 ENST00000533211.1
SPTBN2
spectrin, beta, non-erythrocytic 2
chr12_-_91576429 1.323 ENST00000552145.1
ENST00000546745.1
DCN

decorin

chr1_+_47264711 1.309 ENST00000371923.4
ENST00000271153.4
ENST00000371919.4
CYP4B1


cytochrome P450, family 4, subfamily B, polypeptide 1


chr7_-_121944491 1.309 ENST00000331178.4
ENST00000427185.2
ENST00000442488.2
FEZF1


FEZ family zinc finger 1


chr2_+_45168875 1.298 ENST00000260653.3
SIX3
SIX homeobox 3
chr10_-_105845674 1.283 ENST00000353479.5
ENST00000369733.3
COL17A1

collagen, type XVII, alpha 1

chr15_-_89764929 1.277 ENST00000268125.5
RLBP1
retinaldehyde binding protein 1
chr17_+_34538310 1.160 ENST00000444414.1
ENST00000378350.4
ENST00000389068.5
ENST00000588929.1
ENST00000589079.1
ENST00000589336.1
ENST00000400702.4
ENST00000591167.1
ENST00000586598.1
ENST00000591637.1
ENST00000378352.4
ENST00000358756.5
CCL4L1











chemokine (C-C motif) ligand 4-like 1











chr12_-_91576750 1.153 ENST00000228329.5
ENST00000303320.3
ENST00000052754.5
DCN


decorin


chr17_+_34639793 1.141 ENST00000394465.2
ENST00000394463.2
ENST00000378342.4
CCL4L2


chemokine (C-C motif) ligand 4-like 2


chr20_-_55100981 1.115 ENST00000243913.4
GCNT7
glucosaminyl (N-acetyl) transferase family member 7
chr3_-_195538760 1.111 ENST00000475231.1
MUC4
mucin 4, cell surface associated
chr15_+_63335899 1.104 ENST00000561266.1
TPM1
tropomyosin 1 (alpha)
chr4_+_156588249 1.099 ENST00000393832.3
GUCY1A3
guanylate cyclase 1, soluble, alpha 3
chr2_-_31637560 1.063 ENST00000379416.3
XDH
xanthine dehydrogenase
chr17_+_34640031 1.053 ENST00000339270.6
ENST00000482104.1
CCL4L2

chemokine (C-C motif) ligand 4-like 2

chr19_-_51456344 1.052 ENST00000336334.3
ENST00000593428.1
KLK5

kallikrein-related peptidase 5

chr8_+_102504651 1.037 ENST00000251808.3
ENST00000521085.1
GRHL2

grainyhead-like 2 (Drosophila)

chr5_+_175298487 0.988 ENST00000393745.3
CPLX2
complexin 2
chr1_+_86889769 0.978 ENST00000370565.4
CLCA2
chloride channel accessory 2
chr14_+_79745746 0.975 ENST00000281127.7
NRXN3
neurexin 3
chr20_-_42815733 0.940 ENST00000342272.3
JPH2
junctophilin 2
chr2_+_90108504 0.939 ENST00000390271.2
IGKV6D-41
immunoglobulin kappa variable 6D-41 (non-functional)
chr5_-_149669192 0.933 ENST00000398376.3
CAMK2A
calcium/calmodulin-dependent protein kinase II alpha
chr1_+_117544366 0.877 ENST00000256652.4
ENST00000369470.1
CD101

CD101 molecule

chr6_-_31550192 0.862 ENST00000429299.2
ENST00000446745.2
LTB

lymphotoxin beta (TNF superfamily, member 3)

chr7_+_80275621 0.848 ENST00000426978.1
ENST00000432207.1
CD36

CD36 molecule (thrombospondin receptor)

chr17_-_40575535 0.842 ENST00000357037.5
PTRF
polymerase I and transcript release factor
chr15_+_59903975 0.839 ENST00000560585.1
ENST00000396065.1
GCNT3

glucosaminyl (N-acetyl) transferase 3, mucin type

chr14_+_24540731 0.837 ENST00000558859.1
ENST00000559197.1
ENST00000560828.1
ENST00000216775.2
ENST00000560884.1
CPNE6




copine VI (neuronal)




chr4_+_156588115 0.831 ENST00000455639.2
GUCY1A3
guanylate cyclase 1, soluble, alpha 3
chr4_-_47983519 0.821 ENST00000358519.4
ENST00000544810.1
ENST00000402813.3
CNGA1


cyclic nucleotide gated channel alpha 1


chr20_+_62669472 0.818 ENST00000463337.1
ENST00000358393.1
LINC00176

long intergenic non-protein coding RNA 176

chr7_-_100808843 0.809 ENST00000249330.2
VGF
VGF nerve growth factor inducible
chr14_-_81408063 0.808 ENST00000557411.1
CEP128
centrosomal protein 128kDa
chr20_-_656437 0.789 ENST00000488788.2
RP5-850E9.3
Uncharacterized protein
chr2_-_216003127 0.788 ENST00000412081.1
ENST00000272895.7
ABCA12

ATP-binding cassette, sub-family A (ABC1), member 12

chr2_-_89459813 0.782 ENST00000390256.2
IGKV6-21
immunoglobulin kappa variable 6-21 (non-functional)
chr11_-_111781610 0.766 ENST00000525823.1
CRYAB
crystallin, alpha B
chrX_-_24665208 0.763 ENST00000356768.4
PCYT1B
phosphate cytidylyltransferase 1, choline, beta
chr1_-_205419053 0.762 ENST00000367154.1
LEMD1
LEM domain containing 1
chr3_-_131753830 0.756 ENST00000429747.1
CPNE4
copine IV
chr14_+_79746249 0.753 ENST00000428277.2
NRXN3
neurexin 3
chr11_+_64004888 0.743 ENST00000541681.1
VEGFB
vascular endothelial growth factor B
chr17_+_7387919 0.738 ENST00000572844.1
POLR2A
polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
chr2_+_90060377 0.735 ENST00000436451.2
IGKV6D-21
immunoglobulin kappa variable 6D-21 (non-functional)
chr3_-_124839648 0.731 ENST00000430155.2
SLC12A8
solute carrier family 12, member 8
chr5_-_35195338 0.723 ENST00000509839.1
PRLR
prolactin receptor
chr3_+_47324424 0.721 ENST00000437353.1
ENST00000232766.5
ENST00000455924.2
KLHL18


kelch-like family member 18


chr4_-_80994471 0.708 ENST00000295465.4
ANTXR2
anthrax toxin receptor 2
chr4_-_159094194 0.701 ENST00000592057.1
ENST00000585682.1
ENST00000393807.5
FAM198B


family with sequence similarity 198, member B


chr2_-_113594279 0.697 ENST00000416750.1
ENST00000418817.1
ENST00000263341.2
IL1B


interleukin 1, beta


chr6_-_134639180 0.693 ENST00000367858.5
SGK1
serum/glucocorticoid regulated kinase 1
chr4_-_80994619 0.688 ENST00000404191.1
ANTXR2
anthrax toxin receptor 2
chr3_+_186915274 0.685 ENST00000312295.4
RTP1
receptor (chemosensory) transporter protein 1
chr3_-_187009646 0.668 ENST00000296280.6
ENST00000392470.2
ENST00000169293.6
ENST00000439271.1
ENST00000392472.2
ENST00000392475.2
MASP1





mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)





chr6_-_32145861 0.668 ENST00000336984.6
AGPAT1
1-acylglycerol-3-phosphate O-acyltransferase 1
chr5_-_147162078 0.653 ENST00000507386.1
JAKMIP2
janus kinase and microtubule interacting protein 2
chr15_+_75105170 0.653 ENST00000379709.3
LMAN1L
lectin, mannose-binding, 1 like
chr19_-_35625765 0.650 ENST00000591633.1
LGI4
leucine-rich repeat LGI family, member 4
chr14_+_60975644 0.649 ENST00000327720.5
SIX6
SIX homeobox 6
chr1_+_63063152 0.646 ENST00000371129.3
ANGPTL3
angiopoietin-like 3
chr18_+_29027696 0.646 ENST00000257189.4
DSG3
desmoglein 3
chr14_+_22580233 0.643 ENST00000390454.2
TRAV25
T cell receptor alpha variable 25
chrX_-_138724677 0.637 ENST00000370573.4
ENST00000338585.6
ENST00000370576.4
MCF2


MCF.2 cell line derived transforming sequence


chr14_+_23305760 0.635 ENST00000311852.6
MMP14
matrix metallopeptidase 14 (membrane-inserted)
chr2_-_190044480 0.631 ENST00000374866.3
COL5A2
collagen, type V, alpha 2
chr12_+_66217911 0.628 ENST00000403681.2
HMGA2
high mobility group AT-hook 2
chr1_+_161195781 0.626 ENST00000367988.3
TOMM40L
translocase of outer mitochondrial membrane 40 homolog (yeast)-like
chr7_-_155604967 0.625 ENST00000297261.2
SHH
sonic hedgehog
chr15_-_43910438 0.619 ENST00000432436.1
STRC
stereocilin
chrX_+_122318006 0.614 ENST00000371266.1
ENST00000264357.5
GRIA3

glutamate receptor, ionotropic, AMPA 3

chr4_-_76928641 0.613 ENST00000264888.5
CXCL9
chemokine (C-X-C motif) ligand 9
chr1_-_205904950 0.611 ENST00000340781.4
SLC26A9
solute carrier family 26 (anion exchanger), member 9
chr2_-_24308051 0.610 ENST00000238721.4
ENST00000335934.4
TP53I3

tumor protein p53 inducible protein 3

chr11_-_111781454 0.610 ENST00000533280.1
CRYAB
crystallin, alpha B
chr11_-_111781554 0.608 ENST00000526167.1
ENST00000528961.1
CRYAB

crystallin, alpha B

chr11_+_57105991 0.603 ENST00000263314.2
P2RX3
purinergic receptor P2X, ligand-gated ion channel, 3
chr7_-_99774945 0.601 ENST00000292377.2
GPC2
glypican 2
chr2_+_33172221 0.597 ENST00000354476.3
LTBP1
latent transforming growth factor beta binding protein 1
chr10_-_100995540 0.594 ENST00000370546.1
ENST00000404542.1
HPSE2

heparanase 2

chrX_-_153599578 0.588 ENST00000360319.4
ENST00000344736.4
FLNA

filamin A, alpha

chr4_+_74269956 0.583 ENST00000295897.4
ENST00000415165.2
ENST00000503124.1
ENST00000509063.1
ENST00000401494.3
ALB




albumin




chr15_-_90222642 0.580 ENST00000430628.2
PLIN1
perilipin 1
chr1_+_207039154 0.579 ENST00000367096.3
ENST00000391930.2
IL20

interleukin 20

chr11_+_111126707 0.576 ENST00000280325.4
C11orf53
chromosome 11 open reading frame 53
chr19_-_51141196 0.576 ENST00000338916.4
SYT3
synaptotagmin III
chr20_+_62795827 0.572 ENST00000328439.1
ENST00000536311.1
MYT1

myelin transcription factor 1

chr15_-_90222610 0.571 ENST00000300055.5
PLIN1
perilipin 1
chr5_-_147162263 0.569 ENST00000333010.6
ENST00000265272.5
JAKMIP2

janus kinase and microtubule interacting protein 2

chr16_+_70680439 0.564 ENST00000288098.2
IL34
interleukin 34
chr17_+_4736627 0.559 ENST00000355280.6
ENST00000347992.7
MINK1

misshapen-like kinase 1

chr4_-_16900242 0.558 ENST00000502640.1
ENST00000506732.1
LDB2

LIM domain binding 2

chr6_+_46620705 0.550 ENST00000452689.2
SLC25A27
solute carrier family 25, member 27
chr11_-_111782484 0.550 ENST00000533971.1
CRYAB
crystallin, alpha B
chr12_+_56414851 0.549 ENST00000547167.1
IKZF4
IKAROS family zinc finger 4 (Eos)
chr17_-_60885700 0.547 ENST00000583600.1
MARCH10
membrane-associated ring finger (C3HC4) 10, E3 ubiquitin protein ligase
chr2_-_89327228 0.536 ENST00000483158.1
IGKV3-11
immunoglobulin kappa variable 3-11
chr6_+_25279651 0.536 ENST00000329474.6
LRRC16A
leucine rich repeat containing 16A
chr16_-_29910853 0.535 ENST00000308713.5
SEZ6L2
seizure related 6 homolog (mouse)-like 2
chrX_+_41192595 0.530 ENST00000399959.2
DDX3X
DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
chr17_+_7387677 0.528 ENST00000322644.6
POLR2A
polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
chr16_-_11367452 0.527 ENST00000327157.2
PRM3
protamine 3
chr1_+_32687971 0.525 ENST00000373586.1
EIF3I
eukaryotic translation initiation factor 3, subunit I
chr5_-_177423243 0.524 ENST00000308304.2
PROP1
PROP paired-like homeobox 1
chr12_-_13248598 0.523 ENST00000337630.6
ENST00000545699.1
GSG1

germ cell associated 1

chr6_-_47009996 0.521 ENST00000371243.2
GPR110
G protein-coupled receptor 110
chrX_+_99899180 0.521 ENST00000373004.3
SRPX2
sushi-repeat containing protein, X-linked 2
chr18_-_35145981 0.517 ENST00000420428.2
ENST00000412753.1
CELF4

CUGBP, Elav-like family member 4

chrX_+_122318224 0.514 ENST00000542149.1
GRIA3
glutamate receptor, ionotropic, AMPA 3
chrX_+_28605516 0.511 ENST00000378993.1
IL1RAPL1
interleukin 1 receptor accessory protein-like 1
chr5_-_11588907 0.508 ENST00000513598.1
ENST00000503622.1
CTNND2

catenin (cadherin-associated protein), delta 2

chr22_+_40322623 0.508 ENST00000399090.2
GRAP2
GRB2-related adaptor protein 2
chr19_-_36019123 0.507 ENST00000588674.1
ENST00000452271.2
ENST00000518157.1
SBSN


suprabasin


chr20_+_49126881 0.504 ENST00000371621.3
ENST00000541713.1
PTPN1

protein tyrosine phosphatase, non-receptor type 1

chr22_+_40322595 0.503 ENST00000420971.1
ENST00000544756.1
GRAP2

GRB2-related adaptor protein 2

chr4_-_16900217 0.502 ENST00000441778.2
LDB2
LIM domain binding 2
chr1_+_171154347 0.495 ENST00000209929.7
ENST00000441535.1
FMO2

flavin containing monooxygenase 2 (non-functional)

chr2_-_114036488 0.493 ENST00000263335.7
ENST00000397647.3
ENST00000348715.5
ENST00000429538.3
PAX8



paired box 8



chr18_+_49866496 0.492 ENST00000442544.2
DCC
deleted in colorectal carcinoma
chr1_+_207038699 0.490 ENST00000367098.1
IL20
interleukin 20
chr11_+_130318869 0.489 ENST00000299164.2
ADAMTS15
ADAM metallopeptidase with thrombospondin type 1 motif, 15
chrX_-_131623982 0.488 ENST00000370844.1
MBNL3
muscleblind-like splicing regulator 3
chr19_-_43702231 0.487 ENST00000597374.1
ENST00000599371.1
PSG4

pregnancy specific beta-1-glycoprotein 4

chr19_+_35645618 0.484 ENST00000392218.2
ENST00000543307.1
ENST00000392219.2
ENST00000541435.2
ENST00000590686.1
ENST00000342879.3
ENST00000588699.1
FXYD5






FXYD domain containing ion transport regulator 5






chr15_+_75105057 0.481 ENST00000309664.5
ENST00000562810.1
LMAN1L

lectin, mannose-binding, 1 like

chr17_-_60885659 0.481 ENST00000311269.5
MARCH10
membrane-associated ring finger (C3HC4) 10, E3 ubiquitin protein ligase
chr7_-_129251459 0.480 ENST00000608694.1
RP11-448A19.1
RP11-448A19.1
chr19_+_41869894 0.479 ENST00000413014.2
TMEM91
transmembrane protein 91
chr2_+_90211643 0.478 ENST00000390277.2
IGKV3D-11
immunoglobulin kappa variable 3D-11
chr10_-_54531406 0.477 ENST00000373968.3
MBL2
mannose-binding lectin (protein C) 2, soluble
chr16_+_30773636 0.476 ENST00000402121.3
ENST00000565995.1
ENST00000563683.1
ENST00000357890.5
ENST00000565931.1
RNF40




ring finger protein 40, E3 ubiquitin protein ligase




chr4_+_156587979 0.475 ENST00000511507.1
GUCY1A3
guanylate cyclase 1, soluble, alpha 3
chr12_+_101988774 0.471 ENST00000545503.2
ENST00000536007.1
ENST00000541119.1
ENST00000361466.2
ENST00000551300.1
ENST00000550270.1
MYBPC1





myosin binding protein C, slow type





chr4_-_153457197 0.469 ENST00000281708.4
FBXW7
F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
chr17_-_72358001 0.462 ENST00000375366.3
BTBD17
BTB (POZ) domain containing 17
chr1_-_154943212 0.460 ENST00000368445.5
ENST00000448116.2
ENST00000368449.4
SHC1


SHC (Src homology 2 domain containing) transforming protein 1


chr8_+_85618155 0.460 ENST00000523850.1
ENST00000521376.1
RALYL

RALY RNA binding protein-like

chr12_+_101988627 0.457 ENST00000547405.1
ENST00000452455.2
ENST00000441232.1
ENST00000360610.2
ENST00000392934.3
ENST00000547509.1
ENST00000361685.2
ENST00000549145.1
ENST00000553190.1
MYBPC1








myosin binding protein C, slow type








chr11_-_3692597 0.457 ENST00000534359.1
ENST00000250699.2
CHRNA10

cholinergic receptor, nicotinic, alpha 10 (neuronal)

chr14_-_65409438 0.457 ENST00000557049.1
GPX2
glutathione peroxidase 2 (gastrointestinal)
chr4_+_88720698 0.456 ENST00000226284.5
IBSP
integrin-binding sialoprotein
chr11_-_66675371 0.455 ENST00000393955.2
PC
pyruvate carboxylase
chr12_-_6484376 0.453 ENST00000360168.3
ENST00000358945.3
SCNN1A

sodium channel, non-voltage-gated 1 alpha subunit

chr18_+_50278430 0.452 ENST00000578080.1
ENST00000582875.1
ENST00000412726.1
DCC


deleted in colorectal carcinoma


chr1_-_154943002 0.451 ENST00000606391.1
SHC1
SHC (Src homology 2 domain containing) transforming protein 1
chr17_+_43318434 0.451 ENST00000587489.1
FMNL1
formin-like 1
chr2_-_42991257 0.449 ENST00000378661.2
OXER1
oxoeicosanoid (OXE) receptor 1
chr6_-_75915757 0.448 ENST00000322507.8
COL12A1
collagen, type XII, alpha 1
chr6_+_117586713 0.445 ENST00000352536.3
ENST00000326274.5
VGLL2

vestigial like 2 (Drosophila)

chr8_+_128748308 0.441 ENST00000377970.2
MYC
v-myc avian myelocytomatosis viral oncogene homolog
chr7_+_134576317 0.441 ENST00000424922.1
ENST00000495522.1
CALD1

caldesmon 1

chr11_+_111169565 0.437 ENST00000528846.1
COLCA2
colorectal cancer associated 2
chr19_+_35783047 0.433 ENST00000595791.1
ENST00000597035.1
ENST00000537831.2
MAG


myelin associated glycoprotein


chr14_-_98444386 0.429 ENST00000556462.1
ENST00000556138.1
C14orf64

chromosome 14 open reading frame 64

chr3_+_109128837 0.428 ENST00000497996.1
RP11-702L6.4
RP11-702L6.4
chr15_-_77988485 0.427 ENST00000561030.1
LINGO1
leucine rich repeat and Ig domain containing 1
chr3_-_195310802 0.423 ENST00000421243.1
ENST00000453131.1
APOD

apolipoprotein D

chr1_+_50574585 0.421 ENST00000371824.1
ENST00000371823.4
ELAVL4

ELAV like neuron-specific RNA binding protein 4

chr2_+_135011731 0.421 ENST00000281923.2
MGAT5
mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase
chr2_+_33359687 0.418 ENST00000402934.1
ENST00000404525.1
ENST00000407925.1
LTBP1


latent transforming growth factor beta binding protein 1


chr1_+_84873913 0.416 ENST00000370662.3
DNASE2B
deoxyribonuclease II beta
chr6_+_146350267 0.415 ENST00000355289.4
ENST00000282753.1
GRM1

glutamate receptor, metabotropic 1

chr6_+_12290586 0.414 ENST00000379375.5
EDN1
endothelin 1
chr17_-_8055747 0.412 ENST00000317276.4
ENST00000581703.1
PER1

period circadian clock 1

chr8_-_93107443 0.410 ENST00000360348.2
ENST00000520428.1
ENST00000518992.1
ENST00000520556.1
ENST00000518317.1
ENST00000521319.1
ENST00000521375.1
ENST00000518449.1
RUNX1T1







runt-related transcription factor 1; translocated to, 1 (cyclin D-related)







chr1_-_161193349 0.410 ENST00000469730.2
ENST00000463273.1
ENST00000464492.1
ENST00000367990.3
ENST00000470459.2
ENST00000468465.1
ENST00000463812.1
APOA2






apolipoprotein A-II






chr15_+_63414017 0.409 ENST00000413507.2
LACTB
lactamase, beta
chr2_+_220299547 0.408 ENST00000312358.7
SPEG
SPEG complex locus
chr6_-_51952418 0.408 ENST00000371117.3
PKHD1
polycystic kidney and hepatic disease 1 (autosomal recessive)
chr2_+_114195268 0.408 ENST00000259199.4
ENST00000416503.2
ENST00000433343.2
CBWD2


COBW domain containing 2


chr5_-_11589131 0.408 ENST00000511377.1
CTNND2
catenin (cadherin-associated protein), delta 2
chr22_+_37447771 0.406 ENST00000402077.3
ENST00000403888.3
ENST00000456470.1
KCTD17


potassium channel tetramerization domain containing 17


chr5_+_169064245 0.406 ENST00000256935.8
DOCK2
dedicator of cytokinesis 2
chr3_+_42190714 0.402 ENST00000449246.1
TRAK1
trafficking protein, kinesin binding 1
chr14_+_22984601 0.401 ENST00000390509.1
TRAJ28
T cell receptor alpha joining 28
chr4_-_16900410 0.400 ENST00000304523.5
LDB2
LIM domain binding 2
chr20_+_16729003 0.399 ENST00000246081.2
OTOR
otoraplin
chr14_+_22217447 0.395 ENST00000390427.3
TRAV5
T cell receptor alpha variable 5
chr11_+_55594695 0.394 ENST00000378397.1
OR5L2
olfactory receptor, family 5, subfamily L, member 2
chr14_+_22508822 0.394 ENST00000390448.3
TRAV20
T cell receptor alpha variable 20
chr6_-_29324054 0.392 ENST00000543825.1
OR5V1
olfactory receptor, family 5, subfamily V, member 1
chr19_-_51456321 0.389 ENST00000391809.2
KLK5
kallikrein-related peptidase 5
chr11_-_8959758 0.389 ENST00000531618.1
ASCL3
achaete-scute family bHLH transcription factor 3
chr2_-_55277654 0.389 ENST00000337526.6
ENST00000317610.7
ENST00000357732.4
RTN4


reticulon 4


chr8_+_128748466 0.388 ENST00000524013.1
ENST00000520751.1
MYC

v-myc avian myelocytomatosis viral oncogene homolog

chr18_+_10471826 0.386 ENST00000584596.2
APCDD1
adenomatosis polyposis coli down-regulated 1
chr11_-_123065989 0.386 ENST00000448775.2
CLMP
CXADR-like membrane protein

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.2 GO:0060279 regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.6 1.7 GO:0009946 proximal/distal axis specification(GO:0009946)
0.5 1.5 GO:0018153 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.5 2.8 GO:0052551 response to defense-related nitric oxide production by other organism involved in symbiotic interaction(GO:0052551) response to defense-related host nitric oxide production(GO:0052565)
0.5 1.4 GO:0071109 superior temporal gyrus development(GO:0071109)
0.4 1.3 GO:0001172 transcription, RNA-templated(GO:0001172)
0.3 5.2 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.3 0.9 GO:0021965 spinal cord ventral commissure morphogenesis(GO:0021965)
0.3 0.6 GO:1904339 negative regulation of dopaminergic neuron differentiation(GO:1904339)
0.3 0.8 GO:0060557 positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
0.3 0.8 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.3 0.5 GO:0097105 presynaptic membrane assembly(GO:0097105)
0.2 1.7 GO:0031642 negative regulation of myelination(GO:0031642)
0.2 0.7 GO:0021773 striatal medium spiny neuron differentiation(GO:0021773)
0.2 1.4 GO:0002803 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803)
0.2 1.6 GO:0018879 biphenyl metabolic process(GO:0018879)
0.2 0.7 GO:0072186 metanephric cap development(GO:0072185) metanephric cap morphogenesis(GO:0072186) metanephric cap mesenchymal cell proliferation involved in metanephros development(GO:0090094)
0.2 1.1 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.2 0.6 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.2 1.0 GO:0060672 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.2 0.6 GO:2000612 thyroid-stimulating hormone secretion(GO:0070460) regulation of thyroid-stimulating hormone secretion(GO:2000612)
0.2 0.8 GO:0031052 mesodermal-endodermal cell signaling(GO:0003131) programmed DNA elimination(GO:0031049) chromosome breakage(GO:0031052) histone H2A-S139 phosphorylation(GO:0035978) positive regulation of cellular response to X-ray(GO:2000685)
0.2 0.4 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.2 0.6 GO:0060067 cervix development(GO:0060067)
0.2 0.6 GO:0044179 hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
0.2 0.2 GO:1900377 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
0.2 0.2 GO:0046882 negative regulation of follicle-stimulating hormone secretion(GO:0046882)
0.2 0.7 GO:0050928 negative regulation of positive chemotaxis(GO:0050928)
0.2 0.4 GO:1904862 inhibitory synapse assembly(GO:1904862)
0.2 0.5 GO:0048850 hypophysis morphogenesis(GO:0048850)
0.2 0.7 GO:0070101 positive regulation of chemokine-mediated signaling pathway(GO:0070101)
0.2 0.5 GO:2000646 positive regulation of receptor catabolic process(GO:2000646)
0.2 0.5 GO:0046586 regulation of calcium-dependent cell-cell adhesion(GO:0046586)
0.2 0.9 GO:0038161 prolactin signaling pathway(GO:0038161)
0.2 0.8 GO:2000639 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.2 0.5 GO:0010897 negative regulation of triglyceride catabolic process(GO:0010897)
0.2 0.5 GO:0019072 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.2 0.5 GO:0036058 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.2 0.3 GO:0010982 regulation of high-density lipoprotein particle clearance(GO:0010982)
0.1 0.6 GO:0003166 bundle of His development(GO:0003166)
0.1 0.8 GO:2000334 blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.1 1.1 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
0.1 0.6 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.1 0.5 GO:0035627 ceramide transport(GO:0035627)
0.1 0.4 GO:2000910 negative regulation of cholesterol import(GO:0060621) negative regulation of sterol import(GO:2000910)
0.1 0.4 GO:0002277 myeloid dendritic cell activation involved in immune response(GO:0002277)
0.1 1.3 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.1 2.4 GO:0007021 tubulin complex assembly(GO:0007021)
0.1 0.4 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.1 2.5 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.1 1.2 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.1 0.6 GO:1990834 response to odorant(GO:1990834)
0.1 0.5 GO:0034224 cellular response to zinc ion starvation(GO:0034224)
0.1 0.9 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.1 1.1 GO:1902866 regulation of retina development in camera-type eye(GO:1902866)
0.1 0.9 GO:0021546 rhombomere development(GO:0021546)
0.1 0.6 GO:1904154 positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
0.1 0.3 GO:0019056 modulation by virus of host transcription(GO:0019056) positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691) modulation by symbiont of host transcription(GO:0052026)
0.1 0.3 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.1 0.5 GO:0016068 regulation of type I hypersensitivity(GO:0001810) type I hypersensitivity(GO:0016068)
0.1 0.2 GO:0032764 negative regulation of mast cell cytokine production(GO:0032764)
0.1 0.3 GO:0030997 regulation of centriole-centriole cohesion(GO:0030997)
0.1 0.3 GO:0061073 ciliary body morphogenesis(GO:0061073)
0.1 1.2 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.1 0.3 GO:0014740 negative regulation of muscle hyperplasia(GO:0014740) smooth muscle hyperplasia(GO:0014806)
0.1 1.6 GO:0006776 vitamin A metabolic process(GO:0006776)
0.1 0.3 GO:0086092 regulation of the force of heart contraction by cardiac conduction(GO:0086092)
0.1 0.3 GO:0006532 aspartate biosynthetic process(GO:0006532)
0.1 0.6 GO:0051012 microtubule sliding(GO:0051012)
0.1 0.8 GO:0032417 positive regulation of sodium:proton antiporter activity(GO:0032417)
0.1 0.4 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.1 0.6 GO:0016479 negative regulation of transcription from RNA polymerase I promoter(GO:0016479)
0.1 0.4 GO:0036023 limb joint morphogenesis(GO:0036022) embryonic skeletal limb joint morphogenesis(GO:0036023)
0.1 1.4 GO:0021692 cerebellar Purkinje cell layer morphogenesis(GO:0021692)
0.1 0.4 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.1 0.3 GO:0014839 myoblast migration involved in skeletal muscle regeneration(GO:0014839)
0.1 0.2 GO:2000678 negative regulation of transcription regulatory region DNA binding(GO:2000678)
0.1 0.4 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.1 0.7 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.1 1.0 GO:0006657 CDP-choline pathway(GO:0006657)
0.1 0.6 GO:1904058 positive regulation of sensory perception of pain(GO:1904058)
0.1 0.3 GO:1990167 protein K27-linked deubiquitination(GO:1990167)
0.1 1.0 GO:0010669 epithelial structure maintenance(GO:0010669)
0.1 2.6 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.1 0.3 GO:0006001 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.1 0.8 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.1 0.7 GO:0061588 calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylserine scrambling(GO:0061589) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591)
0.1 0.7 GO:0060754 positive regulation of mast cell chemotaxis(GO:0060754)
0.1 0.5 GO:0070995 NADPH oxidation(GO:0070995)
0.1 0.6 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.1 0.2 GO:0044771 meiotic cell cycle phase transition(GO:0044771) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.1 0.5 GO:1903756 positive regulation of dendritic spine maintenance(GO:1902952) regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
0.1 0.3 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
0.1 0.7 GO:0070294 renal sodium ion absorption(GO:0070294)
0.1 0.3 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.1 0.5 GO:0006540 glutamate decarboxylation to succinate(GO:0006540)
0.1 0.5 GO:0071651 positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651)
0.1 0.4 GO:1903906 plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906)
0.1 1.0 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.1 0.5 GO:0070315 G1 to G0 transition involved in cell differentiation(GO:0070315)
0.1 0.3 GO:0002290 gamma-delta T cell activation involved in immune response(GO:0002290) negative regulation of interferon-beta secretion(GO:0035548) regulation of gamma-delta T cell activation involved in immune response(GO:2001191) positive regulation of gamma-delta T cell activation involved in immune response(GO:2001193)
0.1 0.6 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.1 0.2 GO:0021938 ventral midline development(GO:0007418) smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation(GO:0021938)
0.1 0.3 GO:1903597 negative regulation of gap junction assembly(GO:1903597)
0.1 0.3 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.1 0.2 GO:1904861 excitatory synapse assembly(GO:1904861)
0.1 0.1 GO:0006538 glutamate catabolic process(GO:0006538)
0.1 0.3 GO:0051919 positive regulation of fibrinolysis(GO:0051919)
0.1 0.3 GO:2000609 regulation of thyroid hormone generation(GO:2000609)
0.1 0.1 GO:0051495 positive regulation of cytoskeleton organization(GO:0051495)
0.1 0.4 GO:0008063 Toll signaling pathway(GO:0008063)
0.1 0.4 GO:0090649 response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650) response to aldosterone(GO:1904044)
0.1 0.3 GO:0035964 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.1 0.9 GO:0050910 detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.1 0.2 GO:2000110 positive regulation of eating behavior(GO:1904000) regulation of gastro-intestinal system smooth muscle contraction(GO:1904304) positive regulation of gastro-intestinal system smooth muscle contraction(GO:1904306) regulation of small intestine smooth muscle contraction(GO:1904347) positive regulation of small intestine smooth muscle contraction(GO:1904349) small intestine smooth muscle contraction(GO:1990770) negative regulation of macrophage apoptotic process(GO:2000110)
0.1 1.3 GO:0046341 CDP-diacylglycerol metabolic process(GO:0046341)
0.1 0.2 GO:0034124 regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124) negative regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034125)
0.1 0.3 GO:0048496 maintenance of organ identity(GO:0048496)
0.1 0.4 GO:2000323 negative regulation of glucocorticoid receptor signaling pathway(GO:2000323)
0.1 1.0 GO:0038166 angiotensin-activated signaling pathway(GO:0038166)
0.1 0.5 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.1 0.5 GO:1900623 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.1 0.2 GO:0035281 pre-miRNA export from nucleus(GO:0035281)
0.1 0.2 GO:0051088 PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.1 0.3 GO:0007290 spermatid nucleus elongation(GO:0007290)
0.1 0.2 GO:1900276 regulation of proteinase activated receptor activity(GO:1900276) negative regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900737)
0.1 0.3 GO:1900020 regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.1 0.3 GO:0097688 AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688)
0.1 1.1 GO:0045618 positive regulation of keratinocyte differentiation(GO:0045618)
0.1 0.3 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.1 0.2 GO:0007499 ectoderm and mesoderm interaction(GO:0007499) female genitalia morphogenesis(GO:0048807)
0.1 0.1 GO:0007113 endomitotic cell cycle(GO:0007113)
0.1 0.5 GO:1903944 negative regulation of myoblast fusion(GO:1901740) regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.1 0.3 GO:2001168 regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168)
0.1 0.2 GO:0007585 respiratory gaseous exchange(GO:0007585)
0.1 0.5 GO:0021888 hypothalamus gonadotrophin-releasing hormone neuron differentiation(GO:0021886) hypothalamus gonadotrophin-releasing hormone neuron development(GO:0021888)
0.1 0.1 GO:0033594 response to hydroxyisoflavone(GO:0033594)
0.1 0.2 GO:0032972 regulation of muscle filament sliding speed(GO:0032972)
0.1 0.2 GO:0070459 prolactin secretion(GO:0070459)
0.1 0.2 GO:0045964 positive regulation of catecholamine metabolic process(GO:0045915) positive regulation of dopamine metabolic process(GO:0045964)
0.0 0.2 GO:0061762 CAMKK-AMPK signaling cascade(GO:0061762)
0.0 0.2 GO:0007525 somatic muscle development(GO:0007525)
0.0 0.1 GO:0005988 lactose metabolic process(GO:0005988) lactose biosynthetic process(GO:0005989)
0.0 0.2 GO:0060741 prostate gland stromal morphogenesis(GO:0060741) seminal vesicle development(GO:0061107)
0.0 2.6 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.0 0.1 GO:0032006 regulation of TOR signaling(GO:0032006)
0.0 0.1 GO:0071676 negative regulation of mononuclear cell migration(GO:0071676)
0.0 0.2 GO:0045792 negative regulation of cell size(GO:0045792)
0.0 0.1 GO:0002874 regulation of chronic inflammatory response to antigenic stimulus(GO:0002874)
0.0 0.1 GO:0045658 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645) regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.0 0.1 GO:0090294 nitrogen catabolite regulation of transcription from RNA polymerase II promoter(GO:0001079) nitrogen catabolite activation of transcription from RNA polymerase II promoter(GO:0001080) ammonia assimilation cycle(GO:0019676) regulation of urea metabolic process(GO:0034255) intracellular bile acid receptor signaling pathway(GO:0038185) interleukin-17 secretion(GO:0072615) nitrogen catabolite regulation of transcription(GO:0090293) nitrogen catabolite activation of transcription(GO:0090294) regulation of nitrogen cycle metabolic process(GO:1903314) positive regulation of glutamate metabolic process(GO:2000213) regulation of ammonia assimilation cycle(GO:2001248) positive regulation of ammonia assimilation cycle(GO:2001250)
0.0 1.3 GO:0002021 response to dietary excess(GO:0002021)
0.0 0.6 GO:0019532 oxalate transport(GO:0019532)
0.0 0.3 GO:2000546 positive regulation of cell chemotaxis to fibroblast growth factor(GO:1904849) positive regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000546)
0.0 0.4 GO:0071494 cellular response to UV-C(GO:0071494)
0.0 0.1 GO:0050720 interleukin-1 beta biosynthetic process(GO:0050720)
0.0 1.3 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.3 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.0 0.2 GO:0015917 aminophospholipid transport(GO:0015917) regulation of high-density lipoprotein particle assembly(GO:0090107)
0.0 0.1 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.0 0.2 GO:0008065 establishment of blood-nerve barrier(GO:0008065)
0.0 0.2 GO:0071316 cellular response to nicotine(GO:0071316)
0.0 0.1 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.0 0.2 GO:0051552 flavone metabolic process(GO:0051552)
0.0 0.4 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.0 0.1 GO:0003285 septum secundum development(GO:0003285)
0.0 0.6 GO:1903689 regulation of wound healing, spreading of epidermal cells(GO:1903689) negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0 0.4 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873)
0.0 0.4 GO:0043615 astrocyte cell migration(GO:0043615)
0.0 0.4 GO:0019896 axonal transport of mitochondrion(GO:0019896)
0.0 0.6 GO:0015816 glycine transport(GO:0015816)
0.0 0.2 GO:0045726 positive regulation of integrin biosynthetic process(GO:0045726)
0.0 0.2 GO:0006537 glutamate biosynthetic process(GO:0006537) gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.0 0.1 GO:0060168 positive regulation of adenosine receptor signaling pathway(GO:0060168)
0.0 0.0 GO:0097476 spinal cord motor neuron migration(GO:0097476)
0.0 0.4 GO:0048711 positive regulation of astrocyte differentiation(GO:0048711)
0.0 0.3 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.0 0.5 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.1 GO:0016094 polyprenol biosynthetic process(GO:0016094)
0.0 0.1 GO:0051493 regulation of cytoskeleton organization(GO:0051493)
0.0 0.3 GO:0070172 positive regulation of tooth mineralization(GO:0070172)
0.0 0.1 GO:1903028 positive regulation of opsonization(GO:1903028)
0.0 0.3 GO:1902715 positive regulation of interferon-gamma secretion(GO:1902715)
0.0 0.2 GO:0019918 peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918)
0.0 0.2 GO:0035811 negative regulation of urine volume(GO:0035811)
0.0 0.2 GO:0045656 negative regulation of monocyte differentiation(GO:0045656)
0.0 0.6 GO:0045657 positive regulation of monocyte differentiation(GO:0045657)
0.0 0.2 GO:0070309 lens fiber cell morphogenesis(GO:0070309)
0.0 1.6 GO:0051602 response to electrical stimulus(GO:0051602)
0.0 0.2 GO:0071895 odontoblast differentiation(GO:0071895)
0.0 0.2 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.0 0.1 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.0 0.2 GO:0007296 vitellogenesis(GO:0007296)
0.0 0.5 GO:0001778 plasma membrane repair(GO:0001778)
0.0 1.3 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.0 0.2 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.0 0.2 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.0 0.2 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.0 0.2 GO:0038060 nitric oxide-cGMP-mediated signaling pathway(GO:0038060)
0.0 0.4 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.1 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.0 0.3 GO:0045636 positive regulation of melanocyte differentiation(GO:0045636)
0.0 0.1 GO:0010949 negative regulation of intestinal phytosterol absorption(GO:0010949) negative regulation of intestinal cholesterol absorption(GO:0045796) intestinal phytosterol absorption(GO:0060752) negative regulation of intestinal lipid absorption(GO:1904730)
0.0 0.1 GO:0002728 negative regulation of natural killer cell cytokine production(GO:0002728)
0.0 0.6 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.3 GO:0002091 negative regulation of receptor internalization(GO:0002091)
0.0 0.4 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.0 0.2 GO:1902963 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.0 0.3 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.0 0.1 GO:2001301 lipoxin biosynthetic process(GO:2001301) lipoxin A4 metabolic process(GO:2001302) lipoxin A4 biosynthetic process(GO:2001303)
0.0 0.9 GO:0032292 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.0 0.2 GO:0010626 regulation of Schwann cell proliferation(GO:0010624) negative regulation of Schwann cell proliferation(GO:0010626)
0.0 0.5 GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.0 0.3 GO:0097264 self proteolysis(GO:0097264)
0.0 0.1 GO:0052696 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.0 0.3 GO:0060700 regulation of ribonuclease activity(GO:0060700)
0.0 0.8 GO:0002385 mucosal immune response(GO:0002385)
0.0 0.1 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.0 0.1 GO:1901253 negative regulation of intracellular transport of viral material(GO:1901253)
0.0 0.3 GO:1904778 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.0 2.1 GO:0006027 glycosaminoglycan catabolic process(GO:0006027)
0.0 0.4 GO:0036315 cellular response to sterol(GO:0036315)
0.0 0.3 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.0 0.0 GO:0042222 interleukin-1 biosynthetic process(GO:0042222)
0.0 0.2 GO:0036111 very long-chain fatty-acyl-CoA metabolic process(GO:0036111)
0.0 0.2 GO:0006642 triglyceride mobilization(GO:0006642)
0.0 0.1 GO:0008204 ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
0.0 1.3 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.0 0.1 GO:0039019 pronephric nephron development(GO:0039019)
0.0 0.2 GO:0046627 negative regulation of insulin receptor signaling pathway(GO:0046627) negative regulation of cellular response to insulin stimulus(GO:1900077)
0.0 0.2 GO:0003383 apical constriction(GO:0003383)
0.0 0.1 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.0 0.5 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.0 0.2 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0 0.1 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
0.0 0.2 GO:0060745 mammary gland branching involved in pregnancy(GO:0060745)
0.0 0.1 GO:2000504 positive regulation of blood vessel remodeling(GO:2000504)
0.0 0.1 GO:0032079 positive regulation of endodeoxyribonuclease activity(GO:0032079)
0.0 0.2 GO:1900121 negative regulation of receptor binding(GO:1900121)
0.0 0.2 GO:0033033 negative regulation of myeloid cell apoptotic process(GO:0033033)
0.0 0.3 GO:0048021 regulation of melanin biosynthetic process(GO:0048021) positive regulation of melanin biosynthetic process(GO:0048023) regulation of secondary metabolite biosynthetic process(GO:1900376) positive regulation of secondary metabolite biosynthetic process(GO:1900378)
0.0 0.4 GO:0090026 positive regulation of monocyte chemotaxis(GO:0090026)
0.0 0.1 GO:0098707 ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
0.0 0.8 GO:0022400 regulation of rhodopsin mediated signaling pathway(GO:0022400)
0.0 0.6 GO:0016048 detection of temperature stimulus(GO:0016048)
0.0 0.1 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
0.0 0.1 GO:0060332 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.0 0.3 GO:0097396 response to interleukin-17(GO:0097396) cellular response to interleukin-17(GO:0097398)
0.0 0.1 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0 0.2 GO:0018344 protein geranylgeranylation(GO:0018344)
0.0 0.1 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0 0.1 GO:0034392 negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.0 0.2 GO:0031953 negative regulation of protein autophosphorylation(GO:0031953)
0.0 0.1 GO:2000664 positive regulation of interleukin-5 secretion(GO:2000664)
0.0 0.4 GO:0051775 response to redox state(GO:0051775)
0.0 0.4 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.0 0.2 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.0 0.1 GO:0071934 thiamine transmembrane transport(GO:0071934)
0.0 0.1 GO:0019255 glucose 1-phosphate metabolic process(GO:0019255)
0.0 0.1 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.0 0.1 GO:0019236 response to pheromone(GO:0019236)
0.0 0.2 GO:0060041 retina development in camera-type eye(GO:0060041)
0.0 0.5 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.1 GO:0021684 cerebellar granular layer morphogenesis(GO:0021683) cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0 0.1 GO:0007402 ganglion mother cell fate determination(GO:0007402)
0.0 0.1 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.1 GO:0010193 response to ozone(GO:0010193)
0.0 0.1 GO:0015862 uridine transport(GO:0015862)
0.0 0.1 GO:1902463 protein localization to cell leading edge(GO:1902463)
0.0 0.1 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.0 2.5 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 0.2 GO:0042670 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0 0.1 GO:1904808 regulation of protein oxidation(GO:1904806) positive regulation of protein oxidation(GO:1904808)
0.0 0.3 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.0 0.2 GO:0061099 negative regulation of protein tyrosine kinase activity(GO:0061099)
0.0 1.0 GO:1901998 toxin transport(GO:1901998)
0.0 0.3 GO:0097062 dendritic spine maintenance(GO:0097062)
0.0 0.2 GO:0021575 hindbrain morphogenesis(GO:0021575)
0.0 0.2 GO:0010629 negative regulation of gene expression(GO:0010629)
0.0 0.1 GO:1990258 box C/D snoRNA 3'-end processing(GO:0000494) box C/D snoRNA metabolic process(GO:0033967) box C/D snoRNA processing(GO:0034963) histone glutamine methylation(GO:1990258)
0.0 0.1 GO:0002326 B cell lineage commitment(GO:0002326)
0.0 0.1 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.0 0.2 GO:0001973 adenosine receptor signaling pathway(GO:0001973)
0.0 0.1 GO:0045040 outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040)
0.0 0.2 GO:0021521 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.0 0.1 GO:1904153 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.0 0.1 GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
0.0 0.0 GO:0014717 regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014717) satellite cell activation involved in skeletal muscle regeneration(GO:0014901)
0.0 0.3 GO:0010867 positive regulation of triglyceride biosynthetic process(GO:0010867)
0.0 0.1 GO:0000432 regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432) positive regulation of transcription by glucose(GO:0046016)
0.0 0.4 GO:0006309 apoptotic DNA fragmentation(GO:0006309)
0.0 0.2 GO:0031346 positive regulation of cell projection organization(GO:0031346)
0.0 0.2 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.0 0.1 GO:0016198 axon choice point recognition(GO:0016198)
0.0 0.1 GO:0048664 neuron fate determination(GO:0048664)
0.0 0.1 GO:1903818 positive regulation of voltage-gated potassium channel activity(GO:1903818)
0.0 0.1 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 1.1 GO:0030049 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.0 0.0 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.0 0.0 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.0 0.5 GO:0006929 substrate-dependent cell migration(GO:0006929)
0.0 0.1 GO:0046460 triglyceride biosynthetic process(GO:0019432) neutral lipid biosynthetic process(GO:0046460) acylglycerol biosynthetic process(GO:0046463)
0.0 0.3 GO:0001502 cartilage condensation(GO:0001502)
0.0 0.2 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.1 GO:0010608 posttranscriptional regulation of gene expression(GO:0010608)
0.0 0.2 GO:0006189 brainstem development(GO:0003360) 'de novo' IMP biosynthetic process(GO:0006189)
0.0 0.0 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.0 0.2 GO:0001780 neutrophil homeostasis(GO:0001780)
0.0 0.1 GO:1903659 regulation of complement-dependent cytotoxicity(GO:1903659)
0.0 0.1 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
0.0 0.3 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.1 GO:0070124 mitochondrial translational initiation(GO:0070124)
0.0 0.4 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.1 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.0 0.3 GO:0034656 nucleobase-containing small molecule catabolic process(GO:0034656)
0.0 0.2 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 2.4 GO:0002377 immunoglobulin production(GO:0002377)
0.0 0.3 GO:1990001 inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001)
0.0 0.5 GO:0045724 positive regulation of cilium assembly(GO:0045724)
0.0 0.3 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.0 0.6 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.0 0.3 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.0 0.1 GO:0098914 membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
0.0 0.4 GO:0030199 collagen fibril organization(GO:0030199)
0.0 1.0 GO:0030317 sperm motility(GO:0030317)
0.0 0.1 GO:0015811 L-cystine transport(GO:0015811)
0.0 0.3 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.0 0.1 GO:0006552 leucine catabolic process(GO:0006552)
0.0 0.0 GO:0090283 regulation of protein glycosylation in Golgi(GO:0090283)
0.0 0.2 GO:0030949 positive regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030949)
0.0 0.1 GO:0002118 aggressive behavior(GO:0002118)
0.0 0.2 GO:0051560 mitochondrial calcium ion homeostasis(GO:0051560)
0.0 0.2 GO:2000210 positive regulation of anoikis(GO:2000210)
0.0 0.8 GO:0050909 sensory perception of taste(GO:0050909)
0.0 0.2 GO:0042359 vitamin D metabolic process(GO:0042359)
0.0 0.5 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.1 GO:0006740 NADPH regeneration(GO:0006740)
0.0 0.1 GO:1990928 response to amino acid starvation(GO:1990928)
0.0 0.1 GO:0038169 somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
0.0 0.3 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.0 0.0 GO:0031179 peptide amidation(GO:0001519) protein amidation(GO:0018032) peptide modification(GO:0031179)
0.0 0.2 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.0 0.0 GO:0052405 negative regulation by host of symbiont molecular function(GO:0052405)
0.0 0.1 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.0 0.1 GO:0086073 cardiac muscle cell-cardiac muscle cell adhesion(GO:0086042) bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.0 0.2 GO:0060395 SMAD protein signal transduction(GO:0060395)
0.0 0.3 GO:0036150 phosphatidylserine acyl-chain remodeling(GO:0036150)
0.0 0.2 GO:0097186 amelogenesis(GO:0097186)
0.0 0.0 GO:0023016 signal transduction by trans-phosphorylation(GO:0023016)
0.0 0.1 GO:1902416 positive regulation of mRNA binding(GO:1902416)
0.0 0.0 GO:0046909 intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445)
0.0 0.1 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.8 GO:0048813 dendrite morphogenesis(GO:0048813)
0.0 0.0 GO:0060674 placenta blood vessel development(GO:0060674)
0.0 0.3 GO:0071577 zinc II ion transmembrane transport(GO:0071577)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.4 GO:0043511 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.3 2.2 GO:0097209 epidermal lamellar body(GO:0097209)
0.3 4.2 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.2 0.8 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.2 0.6 GO:0005588 collagen type V trimer(GO:0005588)
0.2 0.6 GO:0031523 Myb complex(GO:0031523)
0.2 0.8 GO:0038038 G-protein coupled receptor homodimeric complex(GO:0038038)
0.2 0.9 GO:0070435 Shc-EGFR complex(GO:0070435)
0.2 2.7 GO:0097512 cardiac myofibril(GO:0097512)
0.1 0.7 GO:0098843 postsynaptic endocytic zone(GO:0098843)
0.1 0.4 GO:0097453 mesaxon(GO:0097453) ensheathing process(GO:1990015)
0.1 0.6 GO:0030936 collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
0.1 0.8 GO:0070554 synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.1 0.5 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.1 0.4 GO:0030934 anchoring collagen complex(GO:0030934)
0.1 0.3 GO:0034667 integrin alpha3-beta1 complex(GO:0034667)
0.1 1.8 GO:0008091 spectrin(GO:0008091)
0.1 0.8 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.1 1.0 GO:0030314 junctional membrane complex(GO:0030314)
0.1 0.4 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.1 2.7 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.1 0.6 GO:0005784 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.1 0.6 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.1 1.4 GO:0033010 paranodal junction(GO:0033010)
0.1 1.6 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.1 0.2 GO:0002139 stereocilia coupling link(GO:0002139)
0.1 0.3 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.1 0.6 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.1 0.8 GO:0097443 sorting endosome(GO:0097443)
0.1 0.8 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.1 0.3 GO:0034451 centriolar satellite(GO:0034451)
0.1 0.2 GO:0033150 cytoskeletal calyx(GO:0033150)
0.1 0.5 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.1 0.4 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.1 0.3 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.1 1.3 GO:0030056 hemidesmosome(GO:0030056)
0.1 0.2 GO:0042565 RNA nuclear export complex(GO:0042565)
0.1 0.5 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.1 0.2 GO:0072517 viral factory(GO:0039713) cytoplasmic viral factory(GO:0039714) host cell viral assembly compartment(GO:0072517)
0.1 2.1 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 1.3 GO:0000974 Prp19 complex(GO:0000974)
0.1 0.8 GO:0030478 actin cap(GO:0030478)
0.1 1.3 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.1 0.4 GO:0070545 PeBoW complex(GO:0070545)
0.0 0.2 GO:0089701 U2AF(GO:0089701)
0.0 1.1 GO:0005922 connexon complex(GO:0005922)
0.0 0.8 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.3 GO:0032584 growth cone membrane(GO:0032584)
0.0 0.1 GO:0018444 translation release factor complex(GO:0018444)
0.0 0.2 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.5 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.5 GO:0060091 kinocilium(GO:0060091)
0.0 0.2 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 0.2 GO:0005826 actomyosin contractile ring(GO:0005826)
0.0 2.5 GO:0001533 cornified envelope(GO:0001533)
0.0 0.6 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 1.2 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 0.3 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.2 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 0.2 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.0 0.1 GO:0044308 axonal spine(GO:0044308)
0.0 0.3 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.3 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.0 0.2 GO:0044326 dendritic spine neck(GO:0044326)
0.0 0.3 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.1 GO:0036398 TCR signalosome(GO:0036398)
0.0 0.3 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 0.3 GO:0042382 paraspeckles(GO:0042382)
0.0 0.4 GO:0097386 glial cell projection(GO:0097386)
0.0 0.2 GO:0032059 bleb(GO:0032059)
0.0 0.5 GO:0031265 CD95 death-inducing signaling complex(GO:0031265) ripoptosome(GO:0097342)
0.0 0.6 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0 0.2 GO:0000836 Hrd1p ubiquitin ligase complex(GO:0000836)
0.0 0.1 GO:0002169 3-methylcrotonyl-CoA carboxylase complex, mitochondrial(GO:0002169) methylcrotonoyl-CoA carboxylase complex(GO:1905202)
0.0 0.3 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.2 GO:0005614 interstitial matrix(GO:0005614)
0.0 1.1 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.1 GO:0071159 NF-kappaB complex(GO:0071159)
0.0 0.3 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.6 GO:0034706 sodium channel complex(GO:0034706)
0.0 0.3 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.0 0.6 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.3 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 2.7 GO:0005796 Golgi lumen(GO:0005796)
0.0 1.2 GO:0031904 endosome lumen(GO:0031904)
0.0 0.2 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.2 GO:0071438 invadopodium membrane(GO:0071438)
0.0 0.1 GO:0032279 asymmetric synapse(GO:0032279)
0.0 0.7 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 0.3 GO:0005869 dynactin complex(GO:0005869)
0.0 0.1 GO:0036449 microtubule minus-end(GO:0036449)
0.0 0.4 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.1 GO:0030893 meiotic cohesin complex(GO:0030893)
0.0 0.2 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.8 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.1 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.0 1.2 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.0 0.6 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.1 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.0 0.1 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.0 0.1 GO:0005770 late endosome(GO:0005770)
0.0 0.0 GO:0034686 integrin alphav-beta8 complex(GO:0034686)
0.0 0.2 GO:0031209 SCAR complex(GO:0031209)
0.0 0.2 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.3 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.1 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.1 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 1.1 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.0 1.8 GO:0030136 clathrin-coated vesicle(GO:0030136)
0.0 0.3 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 1.2 GO:0005811 lipid particle(GO:0005811)
0.0 1.9 GO:0030666 endocytic vesicle membrane(GO:0030666)
0.0 0.2 GO:0045180 basal cortex(GO:0045180)
0.0 0.1 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.3 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.2 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.6 GO:0043198 dendritic shaft(GO:0043198)
0.0 0.1 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.4 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.0 0.1 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.0 0.1 GO:0014704 intercalated disc(GO:0014704)
0.0 0.2 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.1 GO:0071437 invadopodium(GO:0071437)
0.0 0.1 GO:0005916 fascia adherens(GO:0005916)
0.0 1.3 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.2 GO:0070699 type II activin receptor binding(GO:0070699)
0.4 1.3 GO:0003968 RNA-directed RNA polymerase activity(GO:0003968)
0.4 2.3 GO:0030197 extracellular matrix constituent, lubricant activity(GO:0030197)
0.4 1.1 GO:0045518 interleukin-22 receptor binding(GO:0045518)
0.3 0.8 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.3 1.3 GO:0050436 microfibril binding(GO:0050436)
0.2 0.9 GO:0005042 netrin receptor activity(GO:0005042)
0.2 0.9 GO:0030305 heparanase activity(GO:0030305)
0.2 1.0 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.2 0.6 GO:0003881 CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity(GO:0003881)
0.2 0.8 GO:0035501 MH1 domain binding(GO:0035501)
0.2 0.8 GO:0034040 lipid-transporting ATPase activity(GO:0034040)
0.2 0.2 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
0.2 0.9 GO:0004925 prolactin receptor activity(GO:0004925)
0.2 1.3 GO:0005502 11-cis retinal binding(GO:0005502)
0.2 0.2 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.2 1.4 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.2 1.1 GO:0042835 BRE binding(GO:0042835)
0.2 0.7 GO:0031849 olfactory receptor binding(GO:0031849)
0.2 0.5 GO:0030350 iron-responsive element binding(GO:0030350)
0.2 1.8 GO:0030274 LIM domain binding(GO:0030274)
0.2 2.3 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.2 0.8 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.1 0.6 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.1 0.4 GO:0004531 deoxyribonuclease II activity(GO:0004531)
0.1 0.7 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.1 2.3 GO:0097109 neuroligin family protein binding(GO:0097109)
0.1 0.8 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.1 0.4 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.1 0.9 GO:0048408 epidermal growth factor binding(GO:0048408)
0.1 0.9 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.1 0.7 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.1 1.1 GO:0043546 molybdopterin cofactor binding(GO:0043546)
0.1 0.5 GO:0030760 nicotinamide N-methyltransferase activity(GO:0008112) pyridine N-methyltransferase activity(GO:0030760)
0.1 2.7 GO:0004383 guanylate cyclase activity(GO:0004383)
0.1 0.3 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069)
0.1 0.4 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
0.1 1.7 GO:0015643 toxic substance binding(GO:0015643)
0.1 0.3 GO:0004382 guanosine-diphosphatase activity(GO:0004382)
0.1 0.3 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.1 0.8 GO:0050816 phosphothreonine binding(GO:0050816)
0.1 0.4 GO:0016211 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.1 0.6 GO:0004996 thyroid-stimulating hormone receptor activity(GO:0004996)
0.1 0.4 GO:0031708 endothelin B receptor binding(GO:0031708)
0.1 0.2 GO:0098770 FBXO family protein binding(GO:0098770)
0.1 0.6 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.1 2.6 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 0.3 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.1 0.3 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.1 0.2 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.1 0.9 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1 0.2 GO:0008386 cholesterol monooxygenase (side-chain-cleaving) activity(GO:0008386)
0.1 1.2 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.1 0.3 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.1 0.3 GO:0030107 HLA-A specific inhibitory MHC class I receptor activity(GO:0030107)
0.1 0.2 GO:0102008 cytosolic dipeptidase activity(GO:0102008)
0.1 1.2 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.1 0.2 GO:0015403 thiamine uptake transmembrane transporter activity(GO:0015403)
0.1 0.6 GO:0043237 laminin-1 binding(GO:0043237)
0.1 0.4 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.1 4.9 GO:0050840 extracellular matrix binding(GO:0050840)
0.1 0.6 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.1 0.4 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 1.3 GO:0001222 transcription corepressor binding(GO:0001222)
0.1 0.4 GO:0043515 kinetochore binding(GO:0043515)
0.1 0.8 GO:0043855 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.1 0.6 GO:0015288 porin activity(GO:0015288)
0.1 0.1 GO:0004485 methylcrotonoyl-CoA carboxylase activity(GO:0004485)
0.1 0.5 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.1 0.6 GO:0004075 biotin carboxylase activity(GO:0004075) biotin binding(GO:0009374)
0.1 0.2 GO:0034188 apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.1 0.4 GO:0097108 hedgehog family protein binding(GO:0097108)
0.1 0.2 GO:0019770 IgG receptor activity(GO:0019770)
0.1 0.2 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.1 1.6 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.1 0.9 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.1 0.5 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.1 0.2 GO:0090631 pre-miRNA transporter activity(GO:0090631)
0.1 0.6 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.1 1.1 GO:0031432 titin binding(GO:0031432)
0.1 1.2 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.1 0.1 GO:0046848 hydroxyapatite binding(GO:0046848)
0.1 0.6 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.1 0.6 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.1 0.1 GO:1990763 arrestin family protein binding(GO:1990763)
0.0 0.4 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.2 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.0 0.5 GO:0033592 RNA strand annealing activity(GO:0033592)
0.0 0.1 GO:1902122 chenodeoxycholic acid binding(GO:1902122)
0.0 0.3 GO:0008240 tripeptidyl-peptidase activity(GO:0008240)
0.0 0.9 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 0.2 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.2 GO:0043208 glycosphingolipid binding(GO:0043208)
0.0 0.2 GO:0051916 granulocyte colony-stimulating factor binding(GO:0051916)
0.0 0.3 GO:0008525 phosphatidylcholine transporter activity(GO:0008525)
0.0 0.8 GO:0005537 mannose binding(GO:0005537)
0.0 0.2 GO:0016520 growth hormone-releasing hormone receptor activity(GO:0016520)
0.0 0.2 GO:0002046 opsin binding(GO:0002046)
0.0 0.2 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.0 0.3 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 0.1 GO:0052642 lysophosphatidic acid phosphatase activity(GO:0052642)
0.0 1.1 GO:0005112 Notch binding(GO:0005112)
0.0 0.5 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.4 GO:1901567 icosanoid binding(GO:0050542) fatty acid derivative binding(GO:1901567)
0.0 0.1 GO:0004461 lactose synthase activity(GO:0004461)
0.0 0.5 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.3 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.0 0.1 GO:0002094 polyprenyltransferase activity(GO:0002094)
0.0 0.2 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.0 0.1 GO:0004998 transferrin receptor activity(GO:0004998)
0.0 0.7 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.1 GO:0051748 UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
0.0 1.2 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.6 GO:0004859 phospholipase inhibitor activity(GO:0004859)
0.0 0.3 GO:0019534 toxin transporter activity(GO:0019534)
0.0 1.4 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.5 GO:0015217 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.0 0.1 GO:0051996 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.0 0.1 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0 0.3 GO:0042731 PH domain binding(GO:0042731)
0.0 0.2 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.0 0.3 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 0.4 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.2 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.4 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.5 GO:0019966 interleukin-1 binding(GO:0019966)
0.0 0.7 GO:0017081 chloride channel regulator activity(GO:0017081)
0.0 0.4 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.0 0.4 GO:0045159 myosin II binding(GO:0045159)
0.0 0.4 GO:0005549 odorant binding(GO:0005549)
0.0 0.4 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.2 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 0.1 GO:0016165 linoleate 13S-lipoxygenase activity(GO:0016165) hepoxilin-epoxide hydrolase activity(GO:0047977)
0.0 0.7 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 0.2 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.3 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 1.0 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.2 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.0 0.6 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 1.0 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.6 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.2 GO:0044594 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity(GO:0033989) 17-beta-hydroxysteroid dehydrogenase (NAD+) activity(GO:0044594)
0.0 0.3 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.0 0.5 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.5 GO:0005522 profilin binding(GO:0005522)
0.0 0.3 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.0 0.3 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.0 0.1 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.2 GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.0 0.2 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 0.1 GO:0070644 vitamin D response element binding(GO:0070644)
0.0 0.2 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.2 GO:0048019 receptor antagonist activity(GO:0048019)
0.0 0.2 GO:0043426 MRF binding(GO:0043426)
0.0 0.3 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 0.7 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.1 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.0 0.2 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 0.7 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.2 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.0 0.2 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.1 GO:0034511 U3 snoRNA binding(GO:0034511)
0.0 0.1 GO:0008745 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745) peptidoglycan receptor activity(GO:0016019)
0.0 0.7 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.4 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.2 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.4 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.4 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.1 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
0.0 0.2 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.2 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 0.1 GO:1990259 protein-glutamine N-methyltransferase activity(GO:0036009) histone-glutamine methyltransferase activity(GO:1990259)
0.0 0.2 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.0 0.1 GO:0004630 phospholipase D activity(GO:0004630)
0.0 0.4 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 0.1 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.0 0.1 GO:0098821 BMP receptor activity(GO:0098821)
0.0 0.2 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.6 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.1 GO:0008746 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.0 0.1 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.0 0.4 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.1 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.1 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.0 0.2 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.3 GO:0042379 chemokine receptor binding(GO:0042379)
0.0 4.9 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.3 GO:0005003 ephrin receptor activity(GO:0005003)
0.0 0.1 GO:0003924 GTPase activity(GO:0003924)
0.0 0.4 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.1 GO:0030250 cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
0.0 0.8 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.7 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.6 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.1 GO:0017127 cholesterol transporter activity(GO:0017127)
0.0 0.3 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.1 GO:0035651 AP-1 adaptor complex binding(GO:0035650) AP-3 adaptor complex binding(GO:0035651)
0.0 0.5 GO:0005123 death receptor binding(GO:0005123)
0.0 0.3 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 0.4 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.0 0.1 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.0 0.8 GO:0005158 insulin receptor binding(GO:0005158)
0.0 2.7 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.3 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.5 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.3 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.4 GO:0042288 MHC class I protein binding(GO:0042288)
0.0 0.1 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 0.1 GO:0004994 somatostatin receptor activity(GO:0004994)
0.0 0.2 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.5 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.1 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.0 0.0 GO:0004504 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.0 0.5 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 0.5 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 0.4 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 1.0 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.1 GO:0051525 NFAT protein binding(GO:0051525)
0.0 0.5 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.1 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.0 0.9 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.3 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.1 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.0 0.3 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.4 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.2 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.4 GO:0003700 nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.0 0.0 GO:0004917 interleukin-4 receptor activity(GO:0004913) interleukin-7 receptor activity(GO:0004917)
0.0 0.1 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.0 0.3 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.4 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.3 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.0 GO:1990430 extracellular matrix protein binding(GO:1990430)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 6.9 PID_FRA_PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1 1.3 PID_VEGF_VEGFR_PATHWAY VEGF and VEGFR signaling network
0.1 1.7 SA_MMP_CYTOKINE_CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 3.9 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 0.1 PID_CXCR3_PATHWAY CXCR3-mediated signaling events
0.0 2.2 PID_ALK1_PATHWAY ALK1 signaling events
0.0 2.8 NABA_COLLAGENS Genes encoding collagen proteins
0.0 1.0 PID_TCR_JNK_PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 1.9 PID_NCADHERIN_PATHWAY N-cadherin signaling events
0.0 2.1 PID_IL2_STAT5_PATHWAY IL2 signaling events mediated by STAT5
0.0 1.5 PID_WNT_NONCANONICAL_PATHWAY Noncanonical Wnt signaling pathway
0.0 0.1 PID_S1P_S1P4_PATHWAY S1P4 pathway
0.0 0.7 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.7 PID_CIRCADIAN_PATHWAY Circadian rhythm pathway
0.0 0.6 PID_ANTHRAX_PATHWAY Cellular roles of Anthrax toxin
0.0 0.8 PID_MYC_PATHWAY C-MYC pathway
0.0 1.3 PID_ERBB4_PATHWAY ErbB4 signaling events
0.0 0.8 PID_RHODOPSIN_PATHWAY Visual signal transduction: Rods
0.0 2.2 PID_P75_NTR_PATHWAY p75(NTR)-mediated signaling
0.0 0.5 SA_FAS_SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 7.8 NABA_SECRETED_FACTORS Genes encoding secreted soluble factors
0.0 0.2 PID_CONE_PATHWAY Visual signal transduction: Cones
0.0 0.1 PID_UPA_UPAR_PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.3 PID_BCR_5PATHWAY BCR signaling pathway
0.0 4.1 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.2 PID_RAC1_REG_PATHWAY Regulation of RAC1 activity
0.0 1.1 SIG_CHEMOTAXIS Genes related to chemotaxis
0.0 0.7 PID_NETRIN_PATHWAY Netrin-mediated signaling events
0.0 1.0 PID_FOXO_PATHWAY FoxO family signaling
0.0 0.7 PID_INTEGRIN3_PATHWAY Beta3 integrin cell surface interactions
0.0 0.3 ST_PHOSPHOINOSITIDE_3_KINASE_PATHWAY PI3K Pathway
0.0 0.6 PID_HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.2 SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.1 PID_PI3KCI_AKT_PATHWAY Class I PI3K signaling events mediated by Akt
0.0 1.0 PID_LKB1_PATHWAY LKB1 signaling events
0.0 0.3 PID_ERBB2_ERBB3_PATHWAY ErbB2/ErbB3 signaling events
0.0 0.1 SA_G2_AND_M_PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.9 PID_ENDOTHELIN_PATHWAY Endothelins
0.0 0.3 ST_MYOCYTE_AD_PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 3.0 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.1 ST_GAQ_PATHWAY G alpha q Pathway
0.0 0.3 PID_PDGFRB_PATHWAY PDGFR-beta signaling pathway
0.0 0.2 PID_HIF1A_PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.6 REACTOME_GLYCOPROTEIN_HORMONES Genes involved in Glycoprotein hormones
0.1 4.1 REACTOME_CS_DS_DEGRADATION Genes involved in CS/DS degradation
0.1 3.2 REACTOME_UNBLOCKING_OF_NMDA_RECEPTOR_GLUTAMATE_BINDING_AND_ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.1 1.1 REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.1 2.0 REACTOME_HS_GAG_DEGRADATION Genes involved in HS-GAG degradation
0.1 1.1 REACTOME_PURINE_CATABOLISM Genes involved in Purine catabolism
0.1 1.0 REACTOME_ROLE_OF_SECOND_MESSENGERS_IN_NETRIN1_SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.1 2.0 REACTOME_BETA_DEFENSINS Genes involved in Beta defensins
0.1 1.3 REACTOME_VEGF_LIGAND_RECEPTOR_INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 0.8 REACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 1.7 REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 1.2 REACTOME_TRANSPORT_OF_ORGANIC_ANIONS Genes involved in Transport of organic anions
0.1 1.1 REACTOME_GAP_JUNCTION_ASSEMBLY Genes involved in Gap junction assembly
0.1 0.3 REACTOME_PEPTIDE_HORMONE_BIOSYNTHESIS Genes involved in Peptide hormone biosynthesis
0.0 1.1 REACTOME_VIRAL_MESSENGER_RNA_SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 2.7 REACTOME_NITRIC_OXIDE_STIMULATES_GUANYLATE_CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.0 3.0 REACTOME_STRIATED_MUSCLE_CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.9 REACTOME_SIGNAL_ATTENUATION Genes involved in Signal attenuation
0.0 0.5 REACTOME_RECEPTOR_LIGAND_BINDING_INITIATES_THE_SECOND_PROTEOLYTIC_CLEAVAGE_OF_NOTCH_RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.2 REACTOME_ACYL_CHAIN_REMODELLING_OF_PS Genes involved in Acyl chain remodelling of PS
0.0 0.9 REACTOME_ABCA_TRANSPORTERS_IN_LIPID_HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 1.2 REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 2.8 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.0 0.8 REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 1.3 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.5 REACTOME_COMMON_PATHWAY Genes involved in Common Pathway
0.0 0.9 REACTOME_PROLACTIN_RECEPTOR_SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.5 REACTOME_IRAK1_RECRUITS_IKK_COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 0.9 REACTOME_RNA_POL_I_TRANSCRIPTION_TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 1.0 REACTOME_SYNTHESIS_OF_PC Genes involved in Synthesis of PC
0.0 1.0 REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION Genes involved in Extracellular matrix organization
0.0 0.7 REACTOME_ZINC_TRANSPORTERS Genes involved in Zinc transporters
0.0 1.0 REACTOME_BASIGIN_INTERACTIONS Genes involved in Basigin interactions
0.0 0.4 REACTOME_INHIBITION_OF_INSULIN_SECRETION_BY_ADRENALINE_NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 0.5 REACTOME_REGULATION_OF_IFNG_SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.4 REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.3 REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.8 REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.7 REACTOME_EXTRINSIC_PATHWAY_FOR_APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.3 REACTOME_INTRINSIC_PATHWAY Genes involved in Intrinsic Pathway
0.0 0.4 REACTOME_FGFR1_LIGAND_BINDING_AND_ACTIVATION Genes involved in FGFR1 ligand binding and activation
0.0 0.4 REACTOME_N_GLYCAN_ANTENNAE_ELONGATION Genes involved in N-Glycan antennae elongation
0.0 1.3 REACTOME_CYTOCHROME_P450_ARRANGED_BY_SUBSTRATE_TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.8 REACTOME_SYNTHESIS_OF_PA Genes involved in Synthesis of PA
0.0 0.5 REACTOME_GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.5 REACTOME_TIE2_SIGNALING Genes involved in Tie2 Signaling
0.0 0.4 REACTOME_NEPHRIN_INTERACTIONS Genes involved in Nephrin interactions
0.0 2.1 REACTOME_P75_NTR_RECEPTOR_MEDIATED_SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.0 0.6 REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 1.2 REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.5 REACTOME_PHASE1_FUNCTIONALIZATION_OF_COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.0 1.6 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.2 REACTOME_INITIAL_TRIGGERING_OF_COMPLEMENT Genes involved in Initial triggering of complement
0.0 0.2 REACTOME_MICRORNA_MIRNA_BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.0 0.6 REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.0 0.2 REACTOME_AKT_PHOSPHORYLATES_TARGETS_IN_THE_CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.8 REACTOME_GENERATION_OF_SECOND_MESSENGER_MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.9 REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.3 REACTOME_PRESYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.4 REACTOME_GABA_A_RECEPTOR_ACTIVATION Genes involved in GABA A receptor activation
0.0 0.2 REACTOME_GLUCAGON_TYPE_LIGAND_RECEPTORS Genes involved in Glucagon-type ligand receptors
0.0 0.5 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.4 REACTOME_PIP3_ACTIVATES_AKT_SIGNALING Genes involved in PIP3 activates AKT signaling
0.0 0.2 REACTOME_KERATAN_SULFATE_DEGRADATION Genes involved in Keratan sulfate degradation
0.0 1.1 REACTOME_FORMATION_OF_THE_TERNARY_COMPLEX_AND_SUBSEQUENTLY_THE_43S_COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.4 REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.3 REACTOME_EICOSANOID_LIGAND_BINDING_RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.0 0.3 REACTOME_OTHER_SEMAPHORIN_INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.3 REACTOME_COMPLEMENT_CASCADE Genes involved in Complement cascade
0.0 0.4 REACTOME_THE_ROLE_OF_NEF_IN_HIV1_REPLICATION_AND_DISEASE_PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0 0.5 REACTOME_SEMA4D_IN_SEMAPHORIN_SIGNALING Genes involved in Sema4D in semaphorin signaling
0.0 1.1 REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.2 REACTOME_HDL_MEDIATED_LIPID_TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.4 REACTOME_MUSCLE_CONTRACTION Genes involved in Muscle contraction
0.0 0.6 REACTOME_GLYCEROPHOSPHOLIPID_BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis
0.0 0.5 REACTOME_APOPTOTIC_CLEAVAGE_OF_CELLULAR_PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.2 REACTOME_CREB_PHOSPHORYLATION_THROUGH_THE_ACTIVATION_OF_RAS Genes involved in CREB phosphorylation through the activation of Ras
0.0 0.3 REACTOME_AMINO_ACID_SYNTHESIS_AND_INTERCONVERSION_TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.2 REACTOME_GRB2_SOS_PROVIDES_LINKAGE_TO_MAPK_SIGNALING_FOR_INTERGRINS_ Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 0.7 REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation