Motif ID: FLI1
Z-value: 0.768

Transcription factors associated with FLI1:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
FLI1 | ENSG00000151702.12 | FLI1 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
FLI1 | hg19_v2_chr11_+_128563948_128564003, hg19_v2_chr11_+_128563652_128563689, hg19_v2_chr11_+_128634589_128634685 | 0.55 | 5.6e-03 | Click! |
Top targets:
Showing 1 to 20 of 200 entries
Gene overrepresentation in biological_process category:
Showing 1 to 20 of 437 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 9.9 | GO:0018149 | peptide cross-linking(GO:0018149) |
0.2 | 5.0 | GO:0030502 | negative regulation of bone mineralization(GO:0030502) |
0.2 | 2.9 | GO:0019885 | antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885) |
0.1 | 2.9 | GO:0051602 | response to electrical stimulus(GO:0051602) |
0.5 | 2.4 | GO:0032929 | negative regulation of superoxide anion generation(GO:0032929) |
0.0 | 2.3 | GO:0000289 | nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289) |
0.2 | 2.1 | GO:0030951 | establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951) |
0.1 | 2.1 | GO:0050861 | positive regulation of B cell receptor signaling pathway(GO:0050861) |
0.1 | 2.1 | GO:0031116 | positive regulation of microtubule polymerization(GO:0031116) |
0.4 | 2.0 | GO:0044565 | dendritic cell proliferation(GO:0044565) |
0.2 | 2.0 | GO:1904778 | regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778) |
0.1 | 1.8 | GO:0045721 | negative regulation of gluconeogenesis(GO:0045721) |
0.1 | 1.7 | GO:0090160 | Golgi to lysosome transport(GO:0090160) |
0.0 | 1.7 | GO:0031529 | ruffle organization(GO:0031529) |
0.5 | 1.6 | GO:0032888 | regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846) |
0.0 | 1.6 | GO:0038096 | immune response-regulating cell surface receptor signaling pathway involved in phagocytosis(GO:0002433) Fc-gamma receptor signaling pathway involved in phagocytosis(GO:0038096) |
0.3 | 1.5 | GO:0006203 | dGTP catabolic process(GO:0006203) |
0.2 | 1.5 | GO:0097338 | response to clozapine(GO:0097338) |
0.1 | 1.5 | GO:0003376 | sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520) |
0.0 | 1.5 | GO:0018279 | peptidyl-asparagine modification(GO:0018196) protein N-linked glycosylation via asparagine(GO:0018279) |
Gene overrepresentation in cellular_component category:
Showing 1 to 20 of 184 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 10.5 | GO:0001533 | cornified envelope(GO:0001533) |
0.0 | 6.7 | GO:0005924 | cell-substrate adherens junction(GO:0005924) |
0.0 | 4.6 | GO:0001726 | ruffle(GO:0001726) |
0.0 | 4.5 | GO:0031965 | nuclear membrane(GO:0031965) |
0.2 | 4.2 | GO:0031089 | platelet dense granule lumen(GO:0031089) |
0.1 | 3.1 | GO:0005876 | spindle microtubule(GO:0005876) |
0.1 | 2.8 | GO:0005922 | connexon complex(GO:0005922) |
0.0 | 2.8 | GO:0031093 | platelet alpha granule lumen(GO:0031093) |
0.1 | 2.4 | GO:0030128 | clathrin coat of endocytic vesicle(GO:0030128) |
0.0 | 2.1 | GO:0005905 | clathrin-coated pit(GO:0005905) |
0.1 | 1.9 | GO:0005589 | collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647) |
0.1 | 1.9 | GO:0008250 | oligosaccharyltransferase complex(GO:0008250) |
0.1 | 1.9 | GO:0031095 | platelet dense tubular network membrane(GO:0031095) |
0.1 | 1.9 | GO:0005952 | cAMP-dependent protein kinase complex(GO:0005952) |
0.1 | 1.9 | GO:0035371 | microtubule plus-end(GO:0035371) |
0.0 | 1.9 | GO:0005884 | actin filament(GO:0005884) |
0.0 | 1.8 | GO:0000932 | cytoplasmic mRNA processing body(GO:0000932) |
0.2 | 1.7 | GO:0071541 | eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541) |
0.5 | 1.6 | GO:0055028 | cortical microtubule(GO:0055028) |
0.1 | 1.6 | GO:0008091 | spectrin(GO:0008091) |
Gene overrepresentation in molecular_function category:
Showing 1 to 20 of 283 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.6 | 4.7 | GO:0005134 | interleukin-2 receptor binding(GO:0005134) |
0.0 | 4.6 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
0.0 | 3.6 | GO:0005089 | Rho guanyl-nucleotide exchange factor activity(GO:0005089) |
0.1 | 3.2 | GO:0070006 | metalloaminopeptidase activity(GO:0070006) |
0.0 | 2.7 | GO:0051015 | actin filament binding(GO:0051015) |
0.1 | 2.2 | GO:0030280 | structural constituent of epidermis(GO:0030280) |
0.1 | 2.1 | GO:0035615 | clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748) |
0.1 | 2.1 | GO:0030159 | receptor signaling complex scaffold activity(GO:0030159) |
0.2 | 2.0 | GO:0042731 | PH domain binding(GO:0042731) |
0.2 | 2.0 | GO:0019237 | centromeric DNA binding(GO:0019237) |
0.1 | 1.9 | GO:0008199 | ferric iron binding(GO:0008199) |
0.1 | 1.8 | GO:0051011 | microtubule minus-end binding(GO:0051011) |
0.0 | 1.8 | GO:0001784 | phosphotyrosine binding(GO:0001784) |
0.1 | 1.7 | GO:0004579 | dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579) |
0.1 | 1.7 | GO:0050321 | tau-protein kinase activity(GO:0050321) |
0.0 | 1.7 | GO:0030371 | translation repressor activity(GO:0030371) |
0.0 | 1.7 | GO:0005178 | integrin binding(GO:0005178) |
0.0 | 1.6 | GO:0008574 | ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) |
0.0 | 1.6 | GO:0005158 | insulin receptor binding(GO:0005158) |
0.5 | 1.5 | GO:0035539 | 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity(GO:0008413) 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity(GO:0035539) |
Gene overrepresentation in C2:CP category:
Showing 1 to 20 of 56 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 5.4 | PID_AURORA_B_PATHWAY | Aurora B signaling |
0.0 | 5.4 | PID_TCR_PATHWAY | TCR signaling in naïve CD4+ T cells |
0.0 | 4.3 | NABA_ECM_GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
0.0 | 3.6 | PID_INTEGRIN_A4B1_PATHWAY | Alpha4 beta1 integrin signaling events |
0.0 | 3.5 | PID_HIF1_TFPATHWAY | HIF-1-alpha transcription factor network |
0.0 | 2.5 | NABA_BASEMENT_MEMBRANES | Genes encoding structural components of basement membranes |
0.1 | 2.0 | SA_B_CELL_RECEPTOR_COMPLEXES | Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases. |
0.0 | 2.0 | PID_LKB1_PATHWAY | LKB1 signaling events |
0.1 | 1.7 | SA_TRKA_RECEPTOR | The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth. |
0.0 | 1.7 | PID_RXR_VDR_PATHWAY | RXR and RAR heterodimerization with other nuclear receptor |
0.0 | 1.7 | PID_TAP63_PATHWAY | Validated transcriptional targets of TAp63 isoforms |
0.0 | 1.5 | SIG_CHEMOTAXIS | Genes related to chemotaxis |
0.0 | 1.4 | PID_ERBB1_INTERNALIZATION_PATHWAY | Internalization of ErbB1 |
0.0 | 1.3 | SA_G1_AND_S_PHASES | Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition. |
0.0 | 1.3 | PID_EPHRINB_REV_PATHWAY | Ephrin B reverse signaling |
0.0 | 1.3 | PID_ECADHERIN_NASCENT_AJ_PATHWAY | E-cadherin signaling in the nascent adherens junction |
0.0 | 1.1 | PID_LPA4_PATHWAY | LPA4-mediated signaling events |
0.0 | 1.1 | PID_IGF1_PATHWAY | IGF1 pathway |
0.0 | 1.1 | PID_AURORA_A_PATHWAY | Aurora A signaling |
0.0 | 1.0 | PID_FAK_PATHWAY | Signaling events mediated by focal adhesion kinase |
Gene overrepresentation in C2:CP:REACTOME category:
Showing 1 to 20 of 86 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.0 | 6.1 | REACTOME_MHC_CLASS_II_ANTIGEN_PRESENTATION | Genes involved in MHC class II antigen presentation |
0.1 | 3.2 | REACTOME_RETROGRADE_NEUROTROPHIN_SIGNALLING | Genes involved in Retrograde neurotrophin signalling |
0.1 | 3.1 | REACTOME_RAP1_SIGNALLING | Genes involved in Rap1 signalling |
0.1 | 2.8 | REACTOME_GAP_JUNCTION_ASSEMBLY | Genes involved in Gap junction assembly |
0.0 | 2.2 | REACTOME_NCAM1_INTERACTIONS | Genes involved in NCAM1 interactions |
0.0 | 2.1 | REACTOME_SMOOTH_MUSCLE_CONTRACTION | Genes involved in Smooth Muscle Contraction |
0.0 | 2.1 | REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS | Genes involved in Metabolism of vitamins and cofactors |
0.1 | 2.0 | REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION | Genes involved in Cytosolic tRNA aminoacylation |
0.0 | 2.0 | REACTOME_3_UTR_MEDIATED_TRANSLATIONAL_REGULATION | Genes involved in 3' -UTR-mediated translational regulation |
0.1 | 1.9 | REACTOME_RECRUITMENT_OF_NUMA_TO_MITOTIC_CENTROSOMES | Genes involved in Recruitment of NuMA to mitotic centrosomes |
0.0 | 1.9 | REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS | Genes involved in Golgi Associated Vesicle Biogenesis |
0.1 | 1.7 | REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS | Genes involved in Regulation of gene expression in beta cells |
0.0 | 1.7 | REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION | Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression |
0.1 | 1.6 | REACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION | Genes involved in Hyaluronan uptake and degradation |
0.1 | 1.3 | REACTOME_CD28_DEPENDENT_VAV1_PATHWAY | Genes involved in CD28 dependent Vav1 pathway |
0.0 | 1.3 | REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PI3KGAMMA | Genes involved in G beta:gamma signalling through PI3Kgamma |
0.0 | 1.3 | REACTOME_PPARA_ACTIVATES_GENE_EXPRESSION | Genes involved in PPARA Activates Gene Expression |
0.1 | 1.2 | REACTOME_EGFR_DOWNREGULATION | Genes involved in EGFR downregulation |
0.0 | 1.2 | REACTOME_ADVANCED_GLYCOSYLATION_ENDPRODUCT_RECEPTOR_SIGNALING | Genes involved in Advanced glycosylation endproduct receptor signaling |
0.0 | 1.2 | REACTOME_G_ALPHA1213_SIGNALLING_EVENTS | Genes involved in G alpha (12/13) signalling events |