Motif ID: FOXF2_FOXJ1

Z-value: 0.654

Transcription factors associated with FOXF2_FOXJ1:

Gene SymbolEntrez IDGene Name
FOXF2 ENSG00000137273.3 FOXF2
FOXJ1 ENSG00000129654.7 FOXJ1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
FOXJ1hg19_v2_chr17_-_74137374_741373850.692.1e-04Click!
FOXF2hg19_v2_chr6_+_1389989_13900690.096.9e-01Click!


Activity profile for motif FOXF2_FOXJ1.

activity profile for motif FOXF2_FOXJ1


Sorted Z-values histogram for motif FOXF2_FOXJ1

Sorted Z-values for motif FOXF2_FOXJ1



Network of associatons between targets according to the STRING database.



First level regulatory network of FOXF2_FOXJ1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr13_-_39564993 6.904 ENST00000423210.1
 STOML3
stomatin (EPB72)-like 3
chr12_-_71551652 4.311 ENST00000546561.1
 TSPAN8
tetraspanin 8
chr20_+_31823792 1.754 ENST00000375413.4
ENST00000354297.4
ENST00000375422.2
 BPIFA1


BPI fold containing family A, member 1


chr12_-_71551868 1.546 ENST00000247829.3
 TSPAN8
tetraspanin 8
chr5_-_110062384 1.543 ENST00000429839.2
 TMEM232
transmembrane protein 232
chr5_-_110062349 1.521 ENST00000511883.2
ENST00000455884.2
 TMEM232

transmembrane protein 232

chr5_+_156712372 1.367 ENST00000541131.1
 CYFIP2
cytoplasmic FMR1 interacting protein 2
chr11_-_114466477 1.323 ENST00000375478.3
 NXPE4
neurexophilin and PC-esterase domain family, member 4
chr20_+_9049682 1.320 ENST00000334005.3
ENST00000378473.3
 PLCB4

phospholipase C, beta 4

chr17_-_6947225 1.116 ENST00000574600.1
ENST00000308009.1
ENST00000447225.1
 SLC16A11


solute carrier family 16, member 11


chr11_-_114466471 1.095 ENST00000424261.2
 NXPE4
neurexophilin and PC-esterase domain family, member 4
chr16_+_84178874 1.038 ENST00000378553.5
 DNAAF1
dynein, axonemal, assembly factor 1
chrX_+_9431324 1.017 ENST00000407597.2
ENST00000424279.1
ENST00000536365.1
ENST00000441088.1
ENST00000380961.1
ENST00000415293.1
 TBL1X





transducin (beta)-like 1X-linked





chr7_-_105332084 0.960 ENST00000472195.1
 ATXN7L1
ataxin 7-like 1
chr10_-_13570533 0.954 ENST00000396900.2
ENST00000396898.2
 BEND7

BEN domain containing 7

chr11_+_71791359 0.944 ENST00000419228.1
ENST00000435085.1
ENST00000307198.7
ENST00000538413.1
 LRTOMT



leucine rich transmembrane and O-methyltransferase domain containing



chr3_-_107941209 0.922 ENST00000492106.1
 IFT57
intraflagellar transport 57 homolog (Chlamydomonas)
chr2_-_233877912 0.919 ENST00000264051.3
 NGEF
neuronal guanine nucleotide exchange factor
chr4_-_70518941 0.833 ENST00000286604.4
ENST00000505512.1
ENST00000514019.1
 UGT2A1

UGT2A1
UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus

UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus
chr15_-_40600026 0.814 ENST00000456256.2
ENST00000557821.1
 PLCB2

phospholipase C, beta 2


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 71 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 5.6 GO:1900047 negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.4 1.8 GO:0042710 biofilm formation(GO:0042710) single-species biofilm formation(GO:0044010) single-species biofilm formation in or on host organism(GO:0044407) regulation of single-species biofilm formation(GO:1900190) negative regulation of single-species biofilm formation(GO:1900191) regulation of single-species biofilm formation in or on host organism(GO:1900228) negative regulation of single-species biofilm formation in or on host organism(GO:1900229)
0.1 1.5 GO:0003334 keratinocyte development(GO:0003334)
0.1 1.5 GO:0060972 left/right pattern formation(GO:0060972)
0.1 1.4 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.0 1.3 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 1.1 GO:0050913 sensory perception of bitter taste(GO:0050913)
0.2 1.0 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.2 0.9 GO:0038108 negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108)
0.1 0.9 GO:0061002 negative regulation of dendritic spine morphogenesis(GO:0061002)
0.0 0.9 GO:0019614 catechol-containing compound catabolic process(GO:0019614) catecholamine catabolic process(GO:0042424)
0.1 0.8 GO:0042492 gamma-delta T cell differentiation(GO:0042492)
0.0 0.8 GO:0052695 cellular glucuronidation(GO:0052695)
0.2 0.7 GO:0021986 epithalamus development(GO:0021538) habenula development(GO:0021986)
0.1 0.7 GO:0001712 ectodermal cell fate commitment(GO:0001712)
0.1 0.7 GO:0042996 regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.0 0.7 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.2 0.6 GO:0070428 negative regulation of interleukin-23 production(GO:0032707) regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070428)
0.1 0.6 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.1 0.6 GO:1903546 protein localization to photoreceptor outer segment(GO:1903546)

Gene overrepresentation in cellular_component category:

Showing 1 to 19 of 19 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 6.9 GO:0045121 membrane raft(GO:0045121)
0.1 1.7 GO:0044292 dendrite terminus(GO:0044292)
0.0 1.3 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 1.0 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 1.0 GO:0005876 spindle microtubule(GO:0005876)
0.1 0.9 GO:0034464 BBSome(GO:0034464)
0.1 0.6 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.6 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.1 0.4 GO:0034657 GID complex(GO:0034657)
0.1 0.4 GO:0031673 H zone(GO:0031673)
0.1 0.4 GO:1990130 Iml1 complex(GO:1990130)
0.0 0.4 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.4 GO:0071141 SMAD protein complex(GO:0071141)
0.0 0.4 GO:0000145 exocyst(GO:0000145)
0.1 0.2 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.0 0.2 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.0 0.2 GO:0071953 elastic fiber(GO:0071953)
0.0 0.1 GO:0001940 male pronucleus(GO:0001940)
0.0 0.0 GO:0071438 invadopodium membrane(GO:0071438)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 43 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.9 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.1 1.2 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.1 0.9 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.1 0.9 GO:0034452 dynactin binding(GO:0034452)
0.0 0.9 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 0.8 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.1 0.7 GO:0071253 connexin binding(GO:0071253)
0.0 0.7 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.7 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.2 0.6 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.0 0.6 GO:0070330 aromatase activity(GO:0070330)
0.1 0.5 GO:0001225 RNA polymerase II transcription coactivator binding(GO:0001225)
0.0 0.5 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.5 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.1 0.4 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.1 0.4 GO:0004905 type I interferon receptor activity(GO:0004905)
0.0 0.4 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.4 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 0.4 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.4 GO:0070840 dynein complex binding(GO:0070840)

Gene overrepresentation in C2:CP category:

Showing 1 to 10 of 10 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.4 PID_ECADHERIN_STABILIZATION_PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 1.0 ST_G_ALPHA_I_PATHWAY G alpha i Pathway
0.0 0.9 PID_EPHA_FWDPATHWAY EPHA forward signaling
0.0 0.9 PID_IL6_7_PATHWAY IL6-mediated signaling events
0.0 0.7 PID_FRA_PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.6 PID_THROMBIN_PAR4_PATHWAY PAR4-mediated thrombin signaling events
0.0 0.6 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling
0.0 0.4 PID_ALK2_PATHWAY ALK2 signaling events
0.0 0.3 PID_P38_GAMMA_DELTA_PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.3 PID_EPHA2_FWD_PATHWAY EPHA2 forward signaling

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 13 of 13 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.9 REACTOME_PLC_BETA_MEDIATED_EVENTS Genes involved in PLC beta mediated events
0.1 1.2 REACTOME_RECYCLING_OF_BILE_ACIDS_AND_SALTS Genes involved in Recycling of bile acids and salts
0.0 1.0 REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.9 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK
0.0 0.7 REACTOME_GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.7 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.7 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.0 0.6 REACTOME_IKK_COMPLEX_RECRUITMENT_MEDIATED_BY_RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 0.5 REACTOME_KINESINS Genes involved in Kinesins
0.0 0.4 REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.4 REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.4 REACTOME_REGULATION_OF_IFNA_SIGNALING Genes involved in Regulation of IFNA signaling
0.0 0.2 REACTOME_ABACAVIR_TRANSPORT_AND_METABOLISM Genes involved in Abacavir transport and metabolism