Motif ID: FOXJ2

Z-value: 0.633


Transcription factors associated with FOXJ2:

Gene SymbolEntrez IDGene Name
FOXJ2 ENSG00000065970.4 FOXJ2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
FOXJ2hg19_v2_chr12_+_8185288_81853390.359.0e-02Click!


Activity profile for motif FOXJ2.

activity profile for motif FOXJ2


Sorted Z-values histogram for motif FOXJ2

Sorted Z-values for motif FOXJ2



Network of associatons between targets according to the STRING database.



First level regulatory network of FOXJ2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr11_+_35201826 1.559 ENST00000531873.1
 CD44
CD44 molecule (Indian blood group)
chr3_-_122102065 1.366 ENST00000479899.1
ENST00000291458.5
ENST00000497726.1
 CCDC58


coiled-coil domain containing 58


chr19_+_56989609 1.352 ENST00000601875.1
 ZNF667-AS1
ZNF667 antisense RNA 1 (head to head)
chr1_+_45212074 1.334 ENST00000372217.1
 KIF2C
kinesin family member 2C
chr12_-_8815215 1.206 ENST00000544889.1
ENST00000543369.1
 MFAP5

microfibrillar associated protein 5

chr1_-_197115818 1.146 ENST00000367409.4
ENST00000294732.7
 ASPM

asp (abnormal spindle) homolog, microcephaly associated (Drosophila)

chr12_-_8815299 1.123 ENST00000535336.1
 MFAP5
microfibrillar associated protein 5
chrX_-_107682702 1.031 ENST00000372216.4
 COL4A6
collagen, type IV, alpha 6
chr15_+_67430339 0.995 ENST00000439724.3
 SMAD3
SMAD family member 3
chrX_+_99899180 0.974 ENST00000373004.3
 SRPX2
sushi-repeat containing protein, X-linked 2
chr6_+_31462658 0.915 ENST00000538442.1
 MICB
MHC class I polypeptide-related sequence B
chr1_+_73771844 0.831 ENST00000440762.1
ENST00000444827.1
ENST00000415686.1
ENST00000411903.1
 RP4-598G3.1



RP4-598G3.1



chr10_+_33271469 0.831 ENST00000414157.1
 RP11-462L8.1
RP11-462L8.1
chr4_-_68749745 0.831 ENST00000283916.6
 TMPRSS11D
transmembrane protease, serine 11D
chr1_-_43855444 0.831 ENST00000372455.4
 MED8
mediator complex subunit 8
chr4_-_47983519 0.828 ENST00000358519.4
ENST00000544810.1
ENST00000402813.3
 CNGA1


cyclic nucleotide gated channel alpha 1


chr4_-_68749699 0.823 ENST00000545541.1
 TMPRSS11D
transmembrane protease, serine 11D
chr1_+_165797024 0.795 ENST00000372212.4
 UCK2
uridine-cytidine kinase 2
chr19_-_7058651 0.786 ENST00000333843.4
 MBD3L3
methyl-CpG binding domain protein 3-like 3
chr9_-_21142144 0.737 ENST00000380229.2
 IFNW1
interferon, omega 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 68 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 3.2 GO:0060216 definitive hemopoiesis(GO:0060216)
0.1 2.2 GO:0006346 methylation-dependent chromatin silencing(GO:0006346)
0.0 1.7 GO:0007585 respiratory gaseous exchange(GO:0007585)
0.2 1.6 GO:1900623 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.3 1.3 GO:1903285 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470)
0.1 1.3 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.4 1.1 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.0 1.1 GO:0030574 collagen catabolic process(GO:0030574)
0.2 1.0 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.1 1.0 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.1 0.9 GO:0050689 negative regulation of defense response to virus by host(GO:0050689)
0.2 0.8 GO:0046035 CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
0.2 0.8 GO:1904075 trophectodermal cell proliferation(GO:0001834) regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075)
0.0 0.8 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.0 0.8 GO:0022400 regulation of rhodopsin mediated signaling pathway(GO:0022400)
0.1 0.7 GO:0071477 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.0 0.7 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0 0.7 GO:0051775 response to redox state(GO:0051775)
0.2 0.6 GO:0071894 histone H2B conserved C-terminal lysine ubiquitination(GO:0071894)
0.0 0.6 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 39 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 3.2 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.0 1.7 GO:0001669 acrosomal vesicle(GO:0001669)
0.2 1.6 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.0 1.5 GO:0035371 microtubule plus-end(GO:0035371)
0.0 1.4 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.1 1.1 GO:0005587 collagen type IV trimer(GO:0005587)
0.1 1.1 GO:0036449 microtubule minus-end(GO:0036449)
0.1 1.0 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.2 0.9 GO:1990423 RZZ complex(GO:1990423)
0.1 0.8 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.0 0.8 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.2 0.7 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.0 0.7 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.7 GO:0016592 mediator complex(GO:0016592)
0.1 0.5 GO:0070552 BRISC complex(GO:0070552)
0.0 0.5 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.1 0.4 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.1 0.4 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.1 0.4 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.0 0.4 GO:1990761 growth cone lamellipodium(GO:1990761) growth cone filopodium(GO:1990812)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 43 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 4.2 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 2.2 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 1.6 GO:0005540 hyaluronic acid binding(GO:0005540)
0.3 1.3 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.1 1.3 GO:0019237 centromeric DNA binding(GO:0019237)
0.2 1.0 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.1 0.9 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.0 0.9 GO:0051879 Hsp90 protein binding(GO:0051879)
0.1 0.8 GO:0004849 uridine kinase activity(GO:0004849)
0.1 0.8 GO:0043855 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0 0.8 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.8 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.1 0.7 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.7 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.7 GO:0002162 dystroglycan binding(GO:0002162)
0.2 0.6 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 0.5 GO:0008732 glycine hydroxymethyltransferase activity(GO:0004372) threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.1 0.4 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.0 0.4 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.4 GO:0051425 PTB domain binding(GO:0051425)

Gene overrepresentation in C2:CP category:

Showing 1 to 12 of 12 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 3.2 PID_NOTCH_PATHWAY Notch signaling pathway
0.0 1.6 SA_MMP_CYTOKINE_CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 1.5 PID_AURORA_B_PATHWAY Aurora B signaling
0.0 1.3 PID_ER_NONGENOMIC_PATHWAY Plasma membrane estrogen receptor signaling
0.0 1.1 NABA_COLLAGENS Genes encoding collagen proteins
0.0 1.0 PID_SMAD2_3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.9 PID_ALPHA_SYNUCLEIN_PATHWAY Alpha-synuclein signaling
0.0 0.8 PID_RHODOPSIN_PATHWAY Visual signal transduction: Rods
0.0 0.8 PID_KIT_PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.7 PID_CIRCADIAN_PATHWAY Circadian rhythm pathway
0.0 0.4 PID_GLYPICAN_1PATHWAY Glypican 1 network
0.0 0.3 PID_IL8_CXCR2_PATHWAY IL8- and CXCR2-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 11 of 11 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.6 REACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 1.4 REACTOME_AMYLOIDS Genes involved in Amyloids
0.0 1.3 REACTOME_KINESINS Genes involved in Kinesins
0.0 1.1 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.0 1.0 REACTOME_SIGNALING_BY_NODAL Genes involved in Signaling by NODAL
0.0 0.8 REACTOME_PYRIMIDINE_METABOLISM Genes involved in Pyrimidine metabolism
0.0 0.7 REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.4 REACTOME_THE_NLRP3_INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.4 REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.4 REACTOME_SIGNALING_BY_CONSTITUTIVELY_ACTIVE_EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.2 REACTOME_IRAK2_MEDIATED_ACTIVATION_OF_TAK1_COMPLEX_UPON_TLR7_8_OR_9_STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation