Motif ID: FOXL1

Z-value: 1.020


Transcription factors associated with FOXL1:

Gene SymbolEntrez IDGene Name
FOXL1 ENSG00000176678.4 FOXL1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
FOXL1hg19_v2_chr16_+_86612112_86612123-0.281.9e-01Click!


Activity profile for motif FOXL1.

activity profile for motif FOXL1


Sorted Z-values histogram for motif FOXL1

Sorted Z-values for motif FOXL1



Network of associatons between targets according to the STRING database.



First level regulatory network of FOXL1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_-_100356551 7.532 ENST00000209665.4
ADH7
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr4_-_100356844 5.052 ENST00000437033.2
ADH7
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr6_+_131958436 3.562 ENST00000357639.3
ENST00000543135.1
ENST00000427148.2
ENST00000358229.5
ENPP3



ectonucleotide pyrophosphatase/phosphodiesterase 3



chr5_-_35938674 3.562 ENST00000397366.1
ENST00000513623.1
ENST00000514524.1
ENST00000397367.2
CAPSL



calcyphosine-like



chr5_-_41261540 3.057 ENST00000263413.3
C6
complement component 6
chr9_-_34397800 2.779 ENST00000297623.2
C9orf24
chromosome 9 open reading frame 24
chr4_-_100356291 2.740 ENST00000476959.1
ENST00000482593.1
ADH7

alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide

chr5_+_94727048 2.615 ENST00000283357.5
FAM81B
family with sequence similarity 81, member B
chr3_+_8543533 2.601 ENST00000454244.1
LMCD1
LIM and cysteine-rich domains 1
chr5_-_110062384 2.364 ENST00000429839.2
TMEM232
transmembrane protein 232
chr4_-_70505358 2.303 ENST00000457664.2
ENST00000604629.1
ENST00000604021.1
UGT2A2


UDP glucuronosyltransferase 2 family, polypeptide A2


chr18_-_24722995 2.285 ENST00000581714.1
CHST9
carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 9
chr12_+_69742121 2.267 ENST00000261267.2
ENST00000549690.1
ENST00000548839.1
LYZ


lysozyme


chr13_-_39564993 2.254 ENST00000423210.1
STOML3
stomatin (EPB72)-like 3
chr6_+_112408768 2.251 ENST00000368656.2
ENST00000604268.1
FAM229B

family with sequence similarity 229, member B

chr5_+_140227048 2.131 ENST00000532602.1
PCDHA9
protocadherin alpha 9
chr5_-_110062349 2.054 ENST00000511883.2
ENST00000455884.2
TMEM232

transmembrane protein 232

chr10_-_28270795 2.017 ENST00000545014.1
ARMC4
armadillo repeat containing 4
chr12_+_20963647 1.988 ENST00000381545.3
SLCO1B3
solute carrier organic anion transporter family, member 1B3
chr4_+_70861647 1.983 ENST00000246895.4
ENST00000381060.2
STATH

statherin

chr12_-_68696652 1.961 ENST00000539972.1
MDM1
Mdm1 nuclear protein homolog (mouse)
chr12_+_20963632 1.956 ENST00000540853.1
ENST00000261196.2
SLCO1B3

solute carrier organic anion transporter family, member 1B3

chr3_+_238273 1.949 ENST00000256509.2
CHL1
cell adhesion molecule L1-like
chr4_-_84035905 1.915 ENST00000311507.4
PLAC8
placenta-specific 8
chr11_+_111385497 1.862 ENST00000375618.4
ENST00000529167.1
ENST00000332814.6
C11orf88


chromosome 11 open reading frame 88


chr14_-_107078851 1.845 ENST00000390628.2
IGHV1-58
immunoglobulin heavy variable 1-58
chr3_-_167098059 1.823 ENST00000392764.1
ENST00000474464.1
ENST00000392766.2
ENST00000485651.1
ZBBX



zinc finger, B-box domain containing



chr5_+_140165876 1.823 ENST00000504120.2
ENST00000394633.3
ENST00000378133.3
PCDHA1


protocadherin alpha 1


chr15_-_56757329 1.814 ENST00000260453.3
MNS1
meiosis-specific nuclear structural 1
chr4_-_84035868 1.801 ENST00000426923.2
ENST00000509973.1
PLAC8

placenta-specific 8

chr6_-_32498046 1.793 ENST00000374975.3
HLA-DRB5
major histocompatibility complex, class II, DR beta 5
chr6_+_163148161 1.754 ENST00000337019.3
ENST00000366889.2
PACRG

PARK2 co-regulated

chr13_+_43355732 1.727 ENST00000313851.1
FAM216B
family with sequence similarity 216, member B
chr11_-_26593649 1.698 ENST00000455601.2
MUC15
mucin 15, cell surface associated
chr1_+_85527987 1.656 ENST00000326813.8
ENST00000294664.6
ENST00000528899.1
WDR63


WD repeat domain 63


chr5_+_140220769 1.622 ENST00000531613.1
ENST00000378123.3
PCDHA8

protocadherin alpha 8

chr6_-_132272504 1.619 ENST00000367976.3
CTGF
connective tissue growth factor
chr11_-_59633951 1.616 ENST00000257264.3
TCN1
transcobalamin I (vitamin B12 binding protein, R binder family)
chr14_-_106642049 1.560 ENST00000390605.2
IGHV1-18
immunoglobulin heavy variable 1-18
chr3_-_112693865 1.550 ENST00000471858.1
ENST00000295863.4
ENST00000308611.3
CD200R1


CD200 receptor 1


chr12_+_109826524 1.513 ENST00000431443.2
MYO1H
myosin IH
chr5_+_140261703 1.500 ENST00000409494.1
ENST00000289272.2
PCDHA13

protocadherin alpha 13

chr2_+_233527443 1.486 ENST00000410095.1
EFHD1
EF-hand domain family, member D1
chr15_-_45670924 1.457 ENST00000396659.3
GATM
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chr4_+_165675197 1.444 ENST00000515485.1
RP11-294O2.2
RP11-294O2.2
chr11_-_26593677 1.442 ENST00000527569.1
MUC15
mucin 15, cell surface associated
chr3_-_149510553 1.434 ENST00000462519.2
ENST00000446160.1
ENST00000383050.3
ANKUB1


ankyrin repeat and ubiquitin domain containing 1


chr10_+_96522361 1.414 ENST00000371321.3
CYP2C19
cytochrome P450, family 2, subfamily C, polypeptide 19
chr11_-_5248294 1.409 ENST00000335295.4
HBB
hemoglobin, beta
chr1_-_75139397 1.404 ENST00000326665.5
C1orf173
chromosome 1 open reading frame 173
chr3_-_148939835 1.378 ENST00000264613.6
CP
ceruloplasmin (ferroxidase)
chr5_-_43412418 1.370 ENST00000537013.1
ENST00000361115.4
CCL28

chemokine (C-C motif) ligand 28

chrX_-_117119243 1.349 ENST00000539496.1
ENST00000469946.1
KLHL13

kelch-like family member 13

chr6_+_32709119 1.346 ENST00000374940.3
HLA-DQA2
major histocompatibility complex, class II, DQ alpha 2
chr10_+_114133773 1.340 ENST00000354655.4
ACSL5
acyl-CoA synthetase long-chain family member 5
chr14_-_106926724 1.322 ENST00000434710.1
IGHV3-43
immunoglobulin heavy variable 3-43
chr15_+_71228826 1.314 ENST00000558456.1
ENST00000560158.2
ENST00000558808.1
ENST00000559806.1
ENST00000559069.1
LRRC49




leucine rich repeat containing 49




chr5_-_41213607 1.314 ENST00000337836.5
ENST00000433294.1
C6

complement component 6

chr12_-_25801478 1.308 ENST00000540106.1
ENST00000445693.1
ENST00000545543.1
ENST00000542224.1
IFLTD1



intermediate filament tail domain containing 1



chr19_-_14992264 1.293 ENST00000327462.2
OR7A17
olfactory receptor, family 7, subfamily A, member 17
chr3_+_113616317 1.288 ENST00000440446.2
ENST00000488680.1
GRAMD1C

GRAM domain containing 1C

chr12_-_71551652 1.281 ENST00000546561.1
TSPAN8
tetraspanin 8
chr3_-_151102529 1.272 ENST00000302632.3
P2RY12
purinergic receptor P2Y, G-protein coupled, 12
chrX_+_36246735 1.237 ENST00000378653.3
CXorf30
chromosome X open reading frame 30
chr21_-_43735628 1.212 ENST00000291525.10
ENST00000518498.1
TFF3

trefoil factor 3 (intestinal)

chr1_-_150738261 1.197 ENST00000448301.2
ENST00000368985.3
CTSS

cathepsin S

chr7_+_116654935 1.179 ENST00000432298.1
ENST00000422922.1
ST7

suppression of tumorigenicity 7

chr21_+_25801041 1.173 ENST00000453784.2
ENST00000423581.1
AP000476.1

AP000476.1

chr17_+_72270429 1.128 ENST00000311014.6
DNAI2
dynein, axonemal, intermediate chain 2
chr10_-_75118611 1.124 ENST00000355577.3
ENST00000394865.1
ENST00000310715.3
ENST00000401621.2
TTC18



tetratricopeptide repeat domain 18



chr17_+_68071389 1.115 ENST00000283936.1
ENST00000392671.1
KCNJ16

potassium inwardly-rectifying channel, subfamily J, member 16

chr4_+_165675269 1.112 ENST00000507311.1
RP11-294O2.2
RP11-294O2.2
chr1_-_227505289 1.100 ENST00000366765.3
CDC42BPA
CDC42 binding protein kinase alpha (DMPK-like)
chr1_+_104293028 1.091 ENST00000370079.3
AMY1C
amylase, alpha 1C (salivary)
chr1_-_86848760 1.042 ENST00000460698.2
ODF2L
outer dense fiber of sperm tails 2-like
chr6_+_140175987 1.037 ENST00000414038.1
ENST00000431609.1
RP5-899B16.1

RP5-899B16.1

chr6_+_29407083 1.017 ENST00000444197.2
OR10C1
olfactory receptor, family 10, subfamily C, member 1 (gene/pseudogene)
chr17_+_26800296 1.000 ENST00000444914.3
ENST00000314669.5
SLC13A2

solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2

chr19_-_9003586 0.997 ENST00000380951.5
MUC16
mucin 16, cell surface associated
chr5_+_140602904 0.965 ENST00000515856.2
ENST00000239449.4
PCDHB14

protocadherin beta 14

chr3_-_112693759 0.960 ENST00000440122.2
ENST00000490004.1
CD200R1

CD200 receptor 1

chr3_-_112564797 0.950 ENST00000398214.1
ENST00000448932.1
CD200R1L

CD200 receptor 1-like

chr6_-_52705641 0.938 ENST00000370989.2
GSTA5
glutathione S-transferase alpha 5
chr12_+_109785708 0.936 ENST00000310903.5
MYO1H
myosin IH
chr6_-_32908792 0.932 ENST00000418107.2
HLA-DMB
major histocompatibility complex, class II, DM beta
chrX_+_36254051 0.926 ENST00000378657.4
CXorf30
chromosome X open reading frame 30
chr10_+_118305435 0.925 ENST00000369221.2
PNLIP
pancreatic lipase
chr10_-_61513201 0.915 ENST00000414264.1
ENST00000594536.1
LINC00948

long intergenic non-protein coding RNA 948

chr16_+_67840986 0.906 ENST00000561639.1
ENST00000567852.1
ENST00000565148.1
ENST00000388833.3
ENST00000561654.1
ENST00000431934.2
TSNAXIP1





translin-associated factor X interacting protein 1





chr12_-_58329888 0.894 ENST00000546580.1
RP11-620J15.3
RP11-620J15.3
chr5_+_121465207 0.889 ENST00000296600.4
ZNF474
zinc finger protein 474
chr5_+_156696362 0.886 ENST00000377576.3
CYFIP2
cytoplasmic FMR1 interacting protein 2
chr4_-_38806404 0.883 ENST00000308979.2
ENST00000505940.1
ENST00000515861.1
TLR1


toll-like receptor 1


chr12_+_119772502 0.877 ENST00000536742.1
ENST00000327554.2
CCDC60

coiled-coil domain containing 60

chr11_-_26588634 0.876 ENST00000436318.2
ENST00000281268.8
MUC15

mucin 15, cell surface associated

chr11_+_86106208 0.874 ENST00000528728.1
CCDC81
coiled-coil domain containing 81
chr4_-_100212132 0.872 ENST00000209668.2
ADH1A
alcohol dehydrogenase 1A (class I), alpha polypeptide
chr20_+_11008408 0.872 ENST00000378252.1
C20orf187
chromosome 20 open reading frame 187
chr5_+_140254884 0.868 ENST00000398631.2
PCDHA12
protocadherin alpha 12
chr11_+_63137251 0.851 ENST00000310969.4
ENST00000279178.3
SLC22A9

solute carrier family 22 (organic anion transporter), member 9

chr7_-_138386097 0.847 ENST00000421622.1
SVOPL
SVOP-like
chr14_+_21359558 0.843 ENST00000304639.3
RNASE3
ribonuclease, RNase A family, 3
chr6_-_15548591 0.833 ENST00000509674.1
DTNBP1
dystrobrevin binding protein 1
chr4_-_110723134 0.832 ENST00000510800.1
ENST00000512148.1
CFI

complement factor I

chr17_+_7788104 0.826 ENST00000380358.4
CHD3
chromodomain helicase DNA binding protein 3
chr10_+_96443378 0.817 ENST00000285979.6
CYP2C18
cytochrome P450, family 2, subfamily C, polypeptide 18
chr17_+_68071458 0.815 ENST00000589377.1
KCNJ16
potassium inwardly-rectifying channel, subfamily J, member 16
chr11_+_71238313 0.808 ENST00000398536.4
KRTAP5-7
keratin associated protein 5-7
chr6_-_20212630 0.807 ENST00000324607.7
ENST00000541730.1
ENST00000536798.1
MBOAT1


membrane bound O-acyltransferase domain containing 1


chr4_-_70518941 0.804 ENST00000286604.4
ENST00000505512.1
ENST00000514019.1
UGT2A1

UGT2A1
UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus

UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus
chr19_+_56717283 0.797 ENST00000376267.1
ZSCAN5C
zinc finger and SCAN domain containing 5C
chr11_+_1940925 0.785 ENST00000453458.1
ENST00000381557.2
ENST00000381589.3
ENST00000381579.3
ENST00000381563.4
ENST00000344578.4
TNNT3





troponin T type 3 (skeletal, fast)





chr1_-_59012365 0.764 ENST00000456980.1
ENST00000482274.2
ENST00000453710.1
ENST00000419242.1
ENST00000358603.2
ENST00000371226.3
ENST00000426139.1
OMA1






OMA1 zinc metallopeptidase






chr19_+_56713670 0.762 ENST00000534327.1
ZSCAN5C
zinc finger and SCAN domain containing 5C
chr3_-_183273477 0.761 ENST00000341319.3
KLHL6
kelch-like family member 6
chr15_-_52587945 0.745 ENST00000443683.2
ENST00000558479.1
ENST00000261839.7
MYO5C


myosin VC


chr12_-_122107549 0.742 ENST00000355329.3
MORN3
MORN repeat containing 3
chr8_+_94767072 0.739 ENST00000452276.1
ENST00000453321.3
ENST00000498673.1
ENST00000518319.1
TMEM67



transmembrane protein 67



chr11_-_108408895 0.730 ENST00000443411.1
ENST00000533052.1
EXPH5

exophilin 5

chr7_+_76751926 0.718 ENST00000285871.4
ENST00000431197.1
CCDC146

coiled-coil domain containing 146

chr15_-_55657428 0.714 ENST00000568543.1
CCPG1
cell cycle progression 1
chr10_+_695888 0.711 ENST00000441152.2
PRR26
proline rich 26
chr13_+_113633620 0.704 ENST00000421756.1
ENST00000375601.3
MCF2L

MCF.2 cell line derived transforming sequence-like

chr6_+_127898312 0.697 ENST00000329722.7
C6orf58
chromosome 6 open reading frame 58
chr5_+_68860949 0.692 ENST00000507595.1
GTF2H2C
general transcription factor IIH, polypeptide 2C
chr1_+_196621156 0.689 ENST00000359637.2
CFH
complement factor H
chr3_-_114035026 0.685 ENST00000570269.1
RP11-553L6.5
RP11-553L6.5
chr4_-_150736962 0.683 ENST00000502345.1
ENST00000510975.1
ENST00000511993.1
RP11-526A4.1


RP11-526A4.1


chr7_+_138818490 0.680 ENST00000430935.1
ENST00000495038.1
ENST00000474035.2
ENST00000478836.2
ENST00000464848.1
ENST00000343187.4
TTC26





tetratricopeptide repeat domain 26





chr16_-_28634874 0.678 ENST00000395609.1
ENST00000350842.4
SULT1A1

sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1

chr3_-_93747425 0.675 ENST00000315099.2
STX19
syntaxin 19
chrX_-_38186811 0.675 ENST00000318842.7
RPGR
retinitis pigmentosa GTPase regulator
chr3_-_100712352 0.667 ENST00000471714.1
ENST00000284322.5
ABI3BP

ABI family, member 3 (NESH) binding protein

chr9_+_27109392 0.664 ENST00000406359.4
TEK
TEK tyrosine kinase, endothelial
chr10_+_94594351 0.664 ENST00000371552.4
EXOC6
exocyst complex component 6
chr13_-_86373536 0.659 ENST00000400286.2
SLITRK6
SLIT and NTRK-like family, member 6
chr11_-_110561721 0.658 ENST00000357139.3
ARHGAP20
Rho GTPase activating protein 20
chr21_-_35884573 0.656 ENST00000399286.2
KCNE1
potassium voltage-gated channel, Isk-related family, member 1
chr12_-_15114658 0.650 ENST00000542276.1
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr1_-_89736434 0.647 ENST00000370459.3
GBP5
guanylate binding protein 5
chr8_+_24151553 0.647 ENST00000265769.4
ENST00000540823.1
ENST00000397649.3
ADAM28


ADAM metallopeptidase domain 28


chrX_-_24045303 0.647 ENST00000328046.8
KLHL15
kelch-like family member 15
chr4_+_36283213 0.645 ENST00000357504.3
DTHD1
death domain containing 1
chr2_+_179184955 0.639 ENST00000315022.2
OSBPL6
oxysterol binding protein-like 6
chr5_+_140235469 0.636 ENST00000506939.2
ENST00000307360.5
PCDHA10

protocadherin alpha 10

chr3_-_165555200 0.630 ENST00000479451.1
ENST00000540653.1
ENST00000488954.1
ENST00000264381.3
BCHE



butyrylcholinesterase



chr12_+_133757995 0.630 ENST00000536435.2
ENST00000228289.5
ENST00000541211.2
ENST00000500625.3
ENST00000539248.2
ENST00000542711.2
ENST00000536899.2
ENST00000542986.2
ENST00000537565.1
ENST00000541975.2
ZNF268









zinc finger protein 268









chr5_+_140248518 0.628 ENST00000398640.2
PCDHA11
protocadherin alpha 11
chr17_+_35851570 0.620 ENST00000394386.1
DUSP14
dual specificity phosphatase 14
chr7_-_138348969 0.620 ENST00000436657.1
SVOPL
SVOP-like
chr14_+_21387491 0.619 ENST00000258817.2
RP11-84C10.2
RP11-84C10.2
chr11_+_100862811 0.617 ENST00000303130.2
TMEM133
transmembrane protein 133
chr8_+_104831554 0.615 ENST00000408894.2
RIMS2
regulating synaptic membrane exocytosis 2
chr10_+_134150835 0.614 ENST00000432555.2
LRRC27
leucine rich repeat containing 27
chr12_-_15114492 0.613 ENST00000541546.1
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr18_+_50278430 0.605 ENST00000578080.1
ENST00000582875.1
ENST00000412726.1
DCC


deleted in colorectal carcinoma


chr12_+_41831485 0.603 ENST00000539469.2
ENST00000298919.7
PDZRN4

PDZ domain containing ring finger 4

chr1_-_216896780 0.601 ENST00000459955.1
ENST00000366937.1
ENST00000408911.3
ENST00000391890.3
ESRRG



estrogen-related receptor gamma



chr2_+_183943464 0.591 ENST00000354221.4
DUSP19
dual specificity phosphatase 19
chr16_-_23724518 0.588 ENST00000457008.2
ERN2
endoplasmic reticulum to nucleus signaling 2
chr13_+_21141208 0.586 ENST00000351808.5
IFT88
intraflagellar transport 88 homolog (Chlamydomonas)
chr1_+_61547894 0.583 ENST00000403491.3
NFIA
nuclear factor I/A
chr9_-_27005686 0.583 ENST00000380055.5
LRRC19
leucine rich repeat containing 19
chr4_-_110723194 0.582 ENST00000394635.3
CFI
complement factor I
chr10_+_96443204 0.577 ENST00000339022.5
CYP2C18
cytochrome P450, family 2, subfamily C, polypeptide 18
chr7_-_37024665 0.575 ENST00000396040.2
ELMO1
engulfment and cell motility 1
chr10_+_96698406 0.572 ENST00000260682.6
CYP2C9
cytochrome P450, family 2, subfamily C, polypeptide 9
chr11_+_112047087 0.571 ENST00000526088.1
ENST00000532593.1
ENST00000531169.1
BCO2


beta-carotene oxygenase 2


chr3_-_172241250 0.568 ENST00000420541.2
ENST00000241261.2
TNFSF10

tumor necrosis factor (ligand) superfamily, member 10

chr13_+_77522632 0.564 ENST00000377462.1
IRG1
immunoresponsive 1 homolog (mouse)
chr4_+_69962212 0.562 ENST00000508661.1
UGT2B7
UDP glucuronosyltransferase 2 family, polypeptide B7
chr9_-_136933615 0.560 ENST00000371834.2
BRD3
bromodomain containing 3
chr14_+_22694606 0.558 ENST00000390463.3
TRAV36DV7
T cell receptor alpha variable 36/delta variable 7
chr11_-_62474803 0.557 ENST00000533982.1
ENST00000360796.5
BSCL2

Berardinelli-Seip congenital lipodystrophy 2 (seipin)

chr11_+_17316870 0.554 ENST00000458064.2
NUCB2
nucleobindin 2
chr8_-_133637624 0.552 ENST00000522789.1
LRRC6
leucine rich repeat containing 6
chr1_+_171283331 0.549 ENST00000367749.3
FMO4
flavin containing monooxygenase 4
chr4_-_130014532 0.546 ENST00000506368.1
ENST00000439369.2
ENST00000503215.1
SCLT1


sodium channel and clathrin linker 1


chr3_-_167371740 0.545 ENST00000466760.1
ENST00000479765.1
WDR49

WD repeat domain 49

chr7_-_92855762 0.543 ENST00000453812.2
ENST00000394468.2
HEPACAM2

HEPACAM family member 2

chr13_+_52436111 0.543 ENST00000242819.4
CCDC70
coiled-coil domain containing 70
chr18_-_52989217 0.542 ENST00000570287.2
TCF4
transcription factor 4
chr6_+_153552455 0.541 ENST00000392385.2
AL590867.1
Uncharacterized protein; cDNA FLJ59044, highly similar to LINE-1 reverse transcriptase homolog
chr17_-_39203519 0.541 ENST00000542137.1
ENST00000391419.3
KRTAP2-1

keratin associated protein 2-1

chr22_-_17702729 0.536 ENST00000449907.2
ENST00000441548.1
ENST00000399839.1
CECR1


cat eye syndrome chromosome region, candidate 1


chr11_-_62911693 0.532 ENST00000417740.1
ENST00000326192.5
SLC22A24

solute carrier family 22, member 24

chr12_-_55375622 0.527 ENST00000316577.8
TESPA1
thymocyte expressed, positive selection associated 1
chr18_+_74240610 0.526 ENST00000578092.1
ENST00000578613.1
ENST00000583578.1
LINC00908


long intergenic non-protein coding RNA 908


chr12_+_64173583 0.526 ENST00000261234.6
TMEM5
transmembrane protein 5
chr1_+_145524891 0.525 ENST00000369304.3
ITGA10
integrin, alpha 10
chr18_-_52989525 0.523 ENST00000457482.3
TCF4
transcription factor 4
chr8_+_94767109 0.522 ENST00000409623.3
ENST00000453906.1
ENST00000521517.1
TMEM67


transmembrane protein 67


chr12_+_74931551 0.518 ENST00000519948.2
ATXN7L3B
ataxin 7-like 3B
chr11_-_102651343 0.517 ENST00000279441.4
ENST00000539681.1
MMP10

matrix metallopeptidase 10 (stromelysin 2)

chr9_-_123239632 0.511 ENST00000416449.1
CDK5RAP2
CDK5 regulatory subunit associated protein 2
chr1_+_109256067 0.511 ENST00000271311.2
FNDC7
fibronectin type III domain containing 7
chr10_-_104211294 0.507 ENST00000239125.1
C10orf95
chromosome 10 open reading frame 95
chr1_-_158301312 0.503 ENST00000368168.3
CD1B
CD1b molecule
chr11_-_5255861 0.501 ENST00000380299.3
HBD
hemoglobin, delta
chr2_+_38177575 0.493 ENST00000407257.1
ENST00000417700.2
ENST00000234195.3
ENST00000442857.1
RMDN2



regulator of microtubule dynamics 2




Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
5.1 15.3 GO:0010430 fatty acid omega-oxidation(GO:0010430)
1.2 3.6 GO:0030505 inorganic diphosphate transport(GO:0030505)
1.1 4.4 GO:0001970 positive regulation of activation of membrane attack complex(GO:0001970)
0.5 1.6 GO:0034059 response to anoxia(GO:0034059)
0.4 1.1 GO:0042495 detection of triacyl bacterial lipopeptide(GO:0042495) detection of bacterial lipopeptide(GO:0070340)
0.4 2.5 GO:0016098 monoterpenoid metabolic process(GO:0016098)
0.4 1.4 GO:0030185 nitric oxide transport(GO:0030185)
0.3 1.0 GO:2001190 positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001190)
0.3 2.0 GO:0071461 cellular response to redox state(GO:0071461)
0.3 0.8 GO:0044278 cell wall disruption in other organism(GO:0044278)
0.2 0.7 GO:0014057 positive regulation of acetylcholine secretion, neurotransmission(GO:0014057)
0.2 1.4 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
0.2 0.6 GO:0014016 neuroblast differentiation(GO:0014016)
0.2 0.6 GO:0045897 positive regulation of transcription during mitosis(GO:0045897)
0.2 1.2 GO:1904139 microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
0.2 0.6 GO:0021965 spinal cord ventral commissure morphogenesis(GO:0021965)
0.2 3.5 GO:0010826 negative regulation of centrosome duplication(GO:0010826)
0.2 0.6 GO:0042214 terpene metabolic process(GO:0042214)
0.2 0.8 GO:0090264 immune complex clearance(GO:0002434) immune complex clearance by monocytes and macrophages(GO:0002436) regulation of immune complex clearance by monocytes and macrophages(GO:0090264)
0.2 3.8 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.2 3.7 GO:0036158 outer dynein arm assembly(GO:0036158)
0.2 1.6 GO:0015889 cobalamin transport(GO:0015889)
0.2 0.5 GO:0035604 fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow(GO:0035602) fibroblast growth factor receptor signaling pathway involved in hemopoiesis(GO:0035603) fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow(GO:0035604)
0.2 0.2 GO:0042488 positive regulation of odontogenesis of dentin-containing tooth(GO:0042488)
0.1 0.7 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.1 2.1 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.1 0.4 GO:1904048 regulation of spontaneous neurotransmitter secretion(GO:1904048)
0.1 1.5 GO:0006600 creatine metabolic process(GO:0006600)
0.1 0.4 GO:0032203 telomere formation via telomerase(GO:0032203)
0.1 0.5 GO:0010387 COP9 signalosome assembly(GO:0010387)
0.1 1.7 GO:0046541 saliva secretion(GO:0046541)
0.1 0.4 GO:0015993 L-ascorbic acid transport(GO:0015882) molecular hydrogen transport(GO:0015993) transepithelial L-ascorbic acid transport(GO:0070904)
0.1 0.5 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.1 0.7 GO:0060005 vestibular reflex(GO:0060005)
0.1 2.2 GO:0070986 left/right axis specification(GO:0070986)
0.1 1.4 GO:0015747 urate transport(GO:0015747)
0.1 0.6 GO:0071630 nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630)
0.1 0.4 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.1 3.7 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.1 0.1 GO:0043467 regulation of generation of precursor metabolites and energy(GO:0043467)
0.1 0.6 GO:0038161 prolactin signaling pathway(GO:0038161)
0.1 0.8 GO:0032621 interleukin-18 production(GO:0032621)
0.1 0.8 GO:0002024 diet induced thermogenesis(GO:0002024)
0.1 0.7 GO:0048014 Tie signaling pathway(GO:0048014)
0.1 0.8 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.1 0.5 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.1 0.9 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.1 0.3 GO:0016256 N-glycan processing to lysosome(GO:0016256)
0.1 0.3 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.1 0.2 GO:0051758 homologous chromosome movement towards spindle pole involved in homologous chromosome segregation(GO:0051758)
0.1 1.2 GO:0060155 platelet dense granule organization(GO:0060155)
0.1 0.3 GO:0051180 vitamin transport(GO:0051180)
0.1 0.3 GO:0002361 CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361)
0.1 0.7 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.1 0.3 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.1 3.4 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.1 0.3 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
0.1 0.4 GO:0052199 negative regulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052199)
0.1 0.7 GO:0055091 phospholipid homeostasis(GO:0055091)
0.1 0.3 GO:0006740 NADPH regeneration(GO:0006740)
0.1 0.3 GO:2000360 negative regulation of binding of sperm to zona pellucida(GO:2000360)
0.1 0.2 GO:0032354 response to follicle-stimulating hormone(GO:0032354)
0.1 0.2 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.1 0.3 GO:0061669 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.1 0.1 GO:0006533 aspartate catabolic process(GO:0006533)
0.1 0.1 GO:0045851 pH reduction(GO:0045851) intracellular pH reduction(GO:0051452)
0.1 0.5 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.1 0.2 GO:1905246 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
0.1 0.2 GO:0050712 negative regulation of interleukin-1 alpha production(GO:0032690) negative regulation of interleukin-1 alpha secretion(GO:0050712)
0.1 0.2 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.1 0.2 GO:0005986 sucrose biosynthetic process(GO:0005986)
0.1 0.2 GO:0038043 interleukin-5-mediated signaling pathway(GO:0038043)
0.1 0.2 GO:0099543 retrograde trans-synaptic signaling by soluble gas(GO:0098923) trans-synaptic signaling by soluble gas(GO:0099543) trans-synaptic signaling by trans-synaptic complex(GO:0099545)
0.1 2.0 GO:0035640 exploration behavior(GO:0035640)
0.1 0.2 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.1 0.2 GO:2000502 negative regulation of natural killer cell chemotaxis(GO:2000502)
0.1 0.1 GO:0060994 regulation of transcription from RNA polymerase II promoter involved in kidney development(GO:0060994)
0.1 0.8 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.1 4.7 GO:0016266 O-glycan processing(GO:0016266)
0.1 0.5 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.1 0.2 GO:0034553 respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
0.1 0.9 GO:1902260 negative regulation of delayed rectifier potassium channel activity(GO:1902260)
0.1 0.4 GO:1990034 cellular response to corticosterone stimulus(GO:0071386) calcium ion export from cell(GO:1990034)
0.1 1.2 GO:0052695 cellular glucuronidation(GO:0052695)
0.1 0.2 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.1 0.2 GO:0035425 autocrine signaling(GO:0035425)
0.1 1.1 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.1 0.2 GO:0010730 negative regulation of hydrogen peroxide biosynthetic process(GO:0010730)
0.1 0.6 GO:0048003 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.0 0.1 GO:0097252 negative regulation of helicase activity(GO:0051097) oligodendrocyte apoptotic process(GO:0097252)
0.0 0.1 GO:1901162 primary amino compound biosynthetic process(GO:1901162)
0.0 0.2 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.0 0.7 GO:0009812 flavonoid metabolic process(GO:0009812)
0.0 0.3 GO:1903575 cornified envelope assembly(GO:1903575)
0.0 0.4 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.0 0.2 GO:0044026 DNA hypermethylation(GO:0044026)
0.0 0.4 GO:1904424 regulation of GTP binding(GO:1904424)
0.0 0.2 GO:0015842 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842)
0.0 0.1 GO:0031443 fast-twitch skeletal muscle fiber contraction(GO:0031443)
0.0 0.3 GO:0039663 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.0 0.4 GO:0006552 leucine catabolic process(GO:0006552)
0.0 2.8 GO:0042073 intraciliary transport(GO:0042073)
0.0 0.0 GO:0009436 glyoxylate catabolic process(GO:0009436)
0.0 0.3 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.0 0.3 GO:0070995 NADPH oxidation(GO:0070995)
0.0 1.3 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0 0.2 GO:0019566 arabinose metabolic process(GO:0019566) L-arabinose metabolic process(GO:0046373)
0.0 1.2 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.0 0.5 GO:0090292 nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0 0.2 GO:1903721 regulation of I-kappaB phosphorylation(GO:1903719) positive regulation of I-kappaB phosphorylation(GO:1903721)
0.0 0.1 GO:0071638 negative regulation of monocyte chemotactic protein-1 production(GO:0071638)
0.0 0.1 GO:0071073 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513) positive regulation of phospholipid biosynthetic process(GO:0071073)
0.0 1.3 GO:0036150 phosphatidylserine acyl-chain remodeling(GO:0036150)
0.0 0.2 GO:0045636 positive regulation of melanocyte differentiation(GO:0045636)
0.0 0.1 GO:0061010 negative regulation of transcription by transcription factor localization(GO:0010621) gall bladder development(GO:0061010)
0.0 0.2 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.0 0.3 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.2 GO:0035587 purinergic receptor signaling pathway(GO:0035587) G-protein coupled purinergic receptor signaling pathway(GO:0035588) G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589) purinergic nucleotide receptor signaling pathway(GO:0035590)
0.0 0.2 GO:0034443 negative regulation of lipoprotein oxidation(GO:0034443)
0.0 0.1 GO:0035928 rRNA import into mitochondrion(GO:0035928)
0.0 0.2 GO:0046391 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.0 0.5 GO:0046415 urate metabolic process(GO:0046415)
0.0 7.3 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.1 GO:0044205 'de novo' UMP biosynthetic process(GO:0044205)
0.0 0.1 GO:0090294 nitrogen catabolite regulation of transcription from RNA polymerase II promoter(GO:0001079) nitrogen catabolite activation of transcription from RNA polymerase II promoter(GO:0001080) regulation of urea metabolic process(GO:0034255) intracellular bile acid receptor signaling pathway(GO:0038185) interleukin-17 secretion(GO:0072615) nitrogen catabolite regulation of transcription(GO:0090293) nitrogen catabolite activation of transcription(GO:0090294) regulation of nitrogen cycle metabolic process(GO:1903314) positive regulation of glutamate metabolic process(GO:2000213) regulation of ammonia assimilation cycle(GO:2001248) positive regulation of ammonia assimilation cycle(GO:2001250)
0.0 1.1 GO:0006825 copper ion transport(GO:0006825)
0.0 0.5 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.2 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.0 0.2 GO:0050916 sensory perception of sweet taste(GO:0050916) sensory perception of umami taste(GO:0050917)
0.0 0.3 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.0 0.2 GO:0090070 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.0 0.4 GO:0007160 cell-matrix adhesion(GO:0007160)
0.0 0.1 GO:0006106 fumarate metabolic process(GO:0006106)
0.0 0.1 GO:0051083 'de novo' cotranslational protein folding(GO:0051083)
0.0 0.8 GO:0002467 germinal center formation(GO:0002467)
0.0 0.2 GO:0043278 response to isoquinoline alkaloid(GO:0014072) response to morphine(GO:0043278)
0.0 0.3 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.0 0.2 GO:0048388 endosomal lumen acidification(GO:0048388)
0.0 0.6 GO:0099500 synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.0 0.6 GO:0097296 activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097296)
0.0 0.1 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.4 GO:0006069 ethanol oxidation(GO:0006069)
0.0 0.2 GO:0042737 drug catabolic process(GO:0042737)
0.0 0.3 GO:1903169 regulation of calcium ion transmembrane transport(GO:1903169)
0.0 0.8 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.1 GO:0031064 negative regulation of histone deacetylation(GO:0031064)
0.0 0.1 GO:0043335 protein unfolding(GO:0043335)
0.0 0.6 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 0.2 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.1 GO:0010956 negative regulation of calcidiol 1-monooxygenase activity(GO:0010956)
0.0 0.2 GO:1902741 interferon-alpha secretion(GO:0072642) regulation of interferon-alpha secretion(GO:1902739) positive regulation of interferon-alpha secretion(GO:1902741)
0.0 0.1 GO:0006990 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
0.0 0.1 GO:0090214 spongiotrophoblast layer developmental growth(GO:0090214)
0.0 1.2 GO:0048741 skeletal muscle fiber development(GO:0048741)
0.0 0.2 GO:0042780 tRNA 3'-end processing(GO:0042780)
0.0 0.6 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.0 0.2 GO:0035754 B cell chemotaxis(GO:0035754)
0.0 0.4 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 0.1 GO:0008616 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.0 0.2 GO:0060333 interferon-gamma-mediated signaling pathway(GO:0060333)
0.0 0.2 GO:1903975 regulation of glial cell migration(GO:1903975)
0.0 0.1 GO:0070173 regulation of enamel mineralization(GO:0070173)
0.0 0.1 GO:1990418 response to insulin-like growth factor stimulus(GO:1990418)
0.0 0.2 GO:1902715 positive regulation of interferon-gamma secretion(GO:1902715)
0.0 0.5 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.0 0.6 GO:0034389 lipid particle organization(GO:0034389)
0.0 0.2 GO:0042359 vitamin D metabolic process(GO:0042359)
0.0 0.3 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0 0.4 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.1 GO:0019470 4-hydroxyproline catabolic process(GO:0019470)
0.0 1.1 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.6 GO:0072189 ureter development(GO:0072189)
0.0 0.2 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659) regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000371) positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000373)
0.0 2.9 GO:0031295 T cell costimulation(GO:0031295)
0.0 0.4 GO:0021794 thalamus development(GO:0021794)
0.0 0.2 GO:0000060 protein import into nucleus, translocation(GO:0000060)
0.0 0.4 GO:0015671 oxygen transport(GO:0015671)
0.0 0.2 GO:1901419 regulation of response to alcohol(GO:1901419)
0.0 0.2 GO:0008298 intracellular mRNA localization(GO:0008298)
0.0 0.1 GO:0001545 primary ovarian follicle growth(GO:0001545)
0.0 0.1 GO:1900738 positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
0.0 0.2 GO:0071285 cellular response to lithium ion(GO:0071285)
0.0 0.3 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.1 GO:1903301 fructose 2,6-bisphosphate metabolic process(GO:0006003) positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.0 0.2 GO:0000422 mitophagy(GO:0000422) mitochondrion disassembly(GO:0061726)
0.0 0.1 GO:0042177 negative regulation of protein catabolic process(GO:0042177)
0.0 0.1 GO:0016246 RNA interference(GO:0016246)
0.0 0.2 GO:0048023 positive regulation of melanin biosynthetic process(GO:0048023) positive regulation of secondary metabolite biosynthetic process(GO:1900378)
0.0 0.2 GO:0001675 acrosome assembly(GO:0001675)
0.0 0.2 GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 0.1 GO:0070346 positive regulation of fat cell proliferation(GO:0070346)
0.0 0.1 GO:0060480 lung goblet cell differentiation(GO:0060480) positive regulation of PERK-mediated unfolded protein response(GO:1903899)
0.0 0.0 GO:2001027 negative regulation of endothelial cell chemotaxis(GO:2001027)
0.0 0.4 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.5 GO:0030220 platelet formation(GO:0030220) platelet morphogenesis(GO:0036344)
0.0 0.1 GO:0033088 regulation of immature T cell proliferation in thymus(GO:0033084) negative regulation of immature T cell proliferation in thymus(GO:0033088)
0.0 0.1 GO:0042991 transcription factor import into nucleus(GO:0042991)
0.0 0.3 GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) negative regulation of cellular response to transforming growth factor beta stimulus(GO:1903845)
0.0 0.4 GO:0016075 rRNA catabolic process(GO:0016075)
0.0 0.4 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.2 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.0 0.2 GO:0060712 spongiotrophoblast layer development(GO:0060712)
0.0 0.1 GO:1902990 leading strand elongation(GO:0006272) mitotic telomere maintenance via semi-conservative replication(GO:1902990)
0.0 0.2 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.1 GO:0000070 mitotic sister chromatid segregation(GO:0000070)
0.0 0.1 GO:0050830 defense response to Gram-positive bacterium(GO:0050830)
0.0 0.1 GO:0070944 neutrophil mediated cytotoxicity(GO:0070942) neutrophil mediated killing of symbiont cell(GO:0070943) neutrophil mediated killing of bacterium(GO:0070944)
0.0 0.1 GO:0071205 protein localization to paranode region of axon(GO:0002175) protein localization to juxtaparanode region of axon(GO:0071205)
0.0 0.1 GO:0002084 protein depalmitoylation(GO:0002084)
0.0 0.3 GO:0009174 UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
0.0 0.1 GO:0010587 miRNA catabolic process(GO:0010587)
0.0 0.1 GO:0014049 positive regulation of glutamate secretion(GO:0014049)
0.0 0.2 GO:0006621 protein retention in ER lumen(GO:0006621)
0.0 0.2 GO:0050821 protein stabilization(GO:0050821)
0.0 0.4 GO:0010842 retina layer formation(GO:0010842)
0.0 0.6 GO:0006699 bile acid biosynthetic process(GO:0006699)
0.0 0.4 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.2 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.0 0.1 GO:0071763 nuclear membrane organization(GO:0071763)
0.0 0.1 GO:1905097 regulation of guanyl-nucleotide exchange factor activity(GO:1905097)
0.0 0.0 GO:1903181 enzyme active site formation(GO:0018307) neuron death in response to hydrogen peroxide(GO:0036476) neuron intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:0036482) positive regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902958) regulation of protein K48-linked deubiquitination(GO:1903093) negative regulation of protein K48-linked deubiquitination(GO:1903094) regulation of dopamine biosynthetic process(GO:1903179) positive regulation of dopamine biosynthetic process(GO:1903181) regulation of hydrogen peroxide-induced neuron death(GO:1903207) negative regulation of hydrogen peroxide-induced neuron death(GO:1903208) regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway(GO:1903383) negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway(GO:1903384) negative regulation of ubiquitin-specific protease activity(GO:2000157)
0.0 0.3 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.2 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.2 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 0.6 GO:0010107 potassium ion import(GO:0010107)
0.0 0.2 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.0 0.2 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.2 GO:0015980 energy derivation by oxidation of organic compounds(GO:0015980)
0.0 0.2 GO:0070301 cellular response to hydrogen peroxide(GO:0070301)
0.0 0.1 GO:0021730 trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740) lung ciliated cell differentiation(GO:0061141) negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.0 0.5 GO:1900047 negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.0 0.6 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.0 0.2 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.0 0.8 GO:0003009 skeletal muscle contraction(GO:0003009)
0.0 0.2 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.1 GO:0006987 activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.0 0.3 GO:0044557 relaxation of smooth muscle(GO:0044557)
0.0 0.2 GO:1903204 negative regulation of oxidative stress-induced neuron death(GO:1903204)
0.0 0.2 GO:0051168 nuclear export(GO:0051168)
0.0 0.1 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.3 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)
0.0 0.1 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.0 0.1 GO:0019348 dolichol metabolic process(GO:0019348)
0.0 0.1 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.0 0.1 GO:0060737 prostate epithelial cord elongation(GO:0060523) prostate gland morphogenetic growth(GO:0060737)
0.0 0.1 GO:1903963 arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.0 0.4 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.0 0.3 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 0.1 GO:0015781 pyrimidine nucleotide-sugar transport(GO:0015781)
0.0 0.1 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.1 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.0 0.1 GO:0035865 cellular response to potassium ion(GO:0035865)
0.0 0.2 GO:0010592 positive regulation of lamellipodium assembly(GO:0010592)
0.0 0.1 GO:0038095 Fc-epsilon receptor signaling pathway(GO:0038095)
0.0 0.4 GO:0050856 regulation of T cell receptor signaling pathway(GO:0050856)
0.0 0.2 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.0 0.4 GO:0090662 ATP hydrolysis coupled transmembrane transport(GO:0090662)
0.0 0.1 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.0 0.3 GO:0097120 receptor localization to synapse(GO:0097120)
0.0 0.2 GO:0070129 regulation of mitochondrial translation(GO:0070129)
0.0 0.3 GO:0030318 melanocyte differentiation(GO:0030318)
0.0 0.2 GO:2000300 regulation of synaptic vesicle exocytosis(GO:2000300)
0.0 0.1 GO:1901526 positive regulation of macromitophagy(GO:1901526) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925)
0.0 0.3 GO:0034367 macromolecular complex remodeling(GO:0034367) protein-lipid complex remodeling(GO:0034368) plasma lipoprotein particle remodeling(GO:0034369)
0.0 0.1 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 4.3 GO:0005579 membrane attack complex(GO:0005579)
0.4 1.1 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.3 1.3 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.2 3.9 GO:0042613 MHC class II protein complex(GO:0042613)
0.2 0.5 GO:0034680 integrin alpha10-beta1 complex(GO:0034680)
0.2 0.5 GO:0043159 acrosomal matrix(GO:0043159)
0.1 0.6 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.1 0.2 GO:0070081 clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.1 0.7 GO:0036021 endolysosome lumen(GO:0036021)
0.1 1.1 GO:0036157 outer dynein arm(GO:0036157)
0.1 1.9 GO:0097225 sperm midpiece(GO:0097225)
0.1 0.4 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.1 2.1 GO:0030992 intraciliary transport particle B(GO:0030992)
0.1 0.2 GO:0000814 ESCRT II complex(GO:0000814)
0.1 1.4 GO:0036038 MKS complex(GO:0036038)
0.1 0.3 GO:1990246 uniplex complex(GO:1990246)
0.1 0.1 GO:0097179 protease inhibitor complex(GO:0097179)
0.1 1.3 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.1 0.7 GO:0000439 core TFIIH complex(GO:0000439)
0.1 0.8 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1 0.4 GO:0044326 dendritic spine neck(GO:0044326)
0.1 0.2 GO:0097224 sperm connecting piece(GO:0097224)
0.1 5.0 GO:0035580 specific granule lumen(GO:0035580)
0.1 0.5 GO:0072588 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.1 0.3 GO:1990769 proximal neuron projection(GO:1990769)
0.0 0.7 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.1 GO:0060053 neurofilament cytoskeleton(GO:0060053)
0.0 0.4 GO:0032389 MutLalpha complex(GO:0032389)
0.0 1.0 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 2.3 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.1 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.0 3.9 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.3 GO:0031467 Cul7-RING ubiquitin ligase complex(GO:0031467)
0.0 4.3 GO:0097014 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.0 0.5 GO:0005833 hemoglobin complex(GO:0005833)
0.0 0.4 GO:0000322 storage vacuole(GO:0000322)
0.0 1.0 GO:0042101 T cell receptor complex(GO:0042101)
0.0 3.5 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 0.8 GO:0005861 troponin complex(GO:0005861)
0.0 0.5 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 4.2 GO:0005796 Golgi lumen(GO:0005796)
0.0 1.7 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.1 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.0 0.5 GO:0097539 ciliary transition fiber(GO:0097539)
0.0 0.1 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.0 0.1 GO:1990742 dense core granule membrane(GO:0032127) microvesicle(GO:1990742)
0.0 0.8 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.1 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.1 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 0.5 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 0.3 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.1 GO:0070557 PCNA-p21 complex(GO:0070557)
0.0 0.5 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.4 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.2 GO:0000836 Hrd1p ubiquitin ligase complex(GO:0000836)
0.0 0.2 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.2 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.0 0.1 GO:0036398 TCR signalosome(GO:0036398)
0.0 0.4 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0 1.0 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.5 GO:0045277 respiratory chain complex IV(GO:0045277)
0.0 0.5 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.8 GO:0030286 dynein complex(GO:0030286)
0.0 0.6 GO:0000145 exocyst(GO:0000145)
0.0 0.1 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.3 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.0 1.9 GO:0016459 myosin complex(GO:0016459)
0.0 0.2 GO:0016012 dystroglycan complex(GO:0016011) sarcoglycan complex(GO:0016012)
0.0 0.4 GO:0033178 proton-transporting two-sector ATPase complex, catalytic domain(GO:0033178)
0.0 0.2 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 0.3 GO:0030658 transport vesicle membrane(GO:0030658)
0.0 2.1 GO:0005814 centriole(GO:0005814)
0.0 0.1 GO:0000235 astral microtubule(GO:0000235) aster(GO:0005818)
0.0 0.0 GO:0070821 tertiary granule membrane(GO:0070821)
0.0 1.5 GO:0031970 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.0 2.3 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 0.5 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 0.2 GO:0032433 filopodium tip(GO:0032433)
0.0 0.1 GO:0032584 growth cone membrane(GO:0032584)
0.0 0.1 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0 0.2 GO:0030424 axon(GO:0030424)
0.0 0.4 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.1 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.0 0.4 GO:0002080 acrosomal membrane(GO:0002080)
0.0 1.0 GO:0045095 keratin filament(GO:0045095)
0.0 0.1 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.4 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.1 GO:0031045 dense core granule(GO:0031045)
0.0 0.6 GO:0031904 endosome lumen(GO:0031904)
0.0 0.1 GO:0005663 DNA replication factor C complex(GO:0005663)
0.0 0.6 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.8 GO:0043235 receptor complex(GO:0043235)
0.0 1.0 GO:0005746 mitochondrial respiratory chain(GO:0005746)
0.0 0.0 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.8 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.1 GO:0071011 precatalytic spliceosome(GO:0071011)
0.0 0.2 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.6 GO:0036064 ciliary basal body(GO:0036064)
0.0 0.1 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.1 GO:1990037 Lewy body core(GO:1990037)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
3.6 14.5 GO:0004031 aldehyde oxidase activity(GO:0004031)
0.6 3.2 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.6 1.9 GO:0046848 hydroxyapatite binding(GO:0046848)
0.4 2.3 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.3 1.0 GO:0015361 low-affinity sodium:dicarboxylate symporter activity(GO:0015361)
0.2 0.7 GO:0017129 triglyceride binding(GO:0017129)
0.2 0.9 GO:0035663 Toll-like receptor 2 binding(GO:0035663)
0.2 1.3 GO:0030492 hemoglobin binding(GO:0030492)
0.2 1.0 GO:0034875 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.2 0.8 GO:0030899 calcium-dependent ATPase activity(GO:0030899)
0.2 0.8 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.2 2.0 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.2 3.9 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.2 0.2 GO:0016623 oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.2 0.6 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.2 0.5 GO:0004923 leukemia inhibitory factor receptor activity(GO:0004923)
0.2 0.6 GO:0005042 netrin receptor activity(GO:0005042)
0.1 1.3 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 1.6 GO:0031419 cobalamin binding(GO:0031419)
0.1 0.7 GO:0004995 tachykinin receptor activity(GO:0004995)
0.1 2.6 GO:0008392 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.1 2.1 GO:0003796 lysozyme activity(GO:0003796)
0.1 0.6 GO:0004925 prolactin receptor activity(GO:0004925)
0.1 0.4 GO:0070890 L-ascorbate:sodium symporter activity(GO:0008520) sodium-dependent multivitamin transmembrane transporter activity(GO:0008523) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.1 0.3 GO:0008746 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.1 0.4 GO:0008431 vitamin E binding(GO:0008431)
0.1 0.7 GO:0050294 steroid sulfotransferase activity(GO:0050294)
0.1 1.3 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.1 2.3 GO:0045504 dynein heavy chain binding(GO:0045504)
0.1 1.4 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 0.8 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.1 1.4 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.1 1.7 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1 0.3 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.1 0.5 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.1 0.4 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.1 0.6 GO:0050682 AF-2 domain binding(GO:0050682)
0.1 0.3 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.1 0.3 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.1 0.4 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.1 1.0 GO:0031433 telethonin binding(GO:0031433)
0.1 0.2 GO:0015222 serotonin transmembrane transporter activity(GO:0015222)
0.1 1.1 GO:0032395 MHC class II receptor activity(GO:0032395)
0.1 2.5 GO:0001968 fibronectin binding(GO:0001968)
0.1 1.3 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.1 1.1 GO:0042834 peptidoglycan binding(GO:0042834)
0.1 0.5 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1 0.2 GO:0008386 cholesterol monooxygenase (side-chain-cleaving) activity(GO:0008386)
0.1 0.3 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.1 0.8 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.1 0.2 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.1 0.6 GO:0030884 lipid antigen binding(GO:0030882) endogenous lipid antigen binding(GO:0030883) exogenous lipid antigen binding(GO:0030884)
0.1 0.2 GO:0004914 interleukin-5 receptor activity(GO:0004914)
0.1 0.3 GO:0047288 monosialoganglioside sialyltransferase activity(GO:0047288)
0.1 0.2 GO:0051430 corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.1 0.2 GO:0097363 protein O-GlcNAc transferase activity(GO:0097363)
0.1 0.5 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.1 0.2 GO:0086062 voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
0.1 0.2 GO:0008384 IkappaB kinase activity(GO:0008384)
0.1 1.7 GO:0042605 peptide antigen binding(GO:0042605)
0.1 0.4 GO:0001594 trace-amine receptor activity(GO:0001594)
0.1 0.2 GO:0032184 SUMO polymer binding(GO:0032184)
0.0 0.2 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.0 0.6 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 1.2 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.0 0.2 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 1.3 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 1.7 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.2 GO:0046556 alpha-L-arabinofuranosidase activity(GO:0046556)
0.0 0.1 GO:0051499 D-aminoacyl-tRNA deacylase activity(GO:0051499) D-tyrosyl-tRNA(Tyr) deacylase activity(GO:0051500)
0.0 0.3 GO:0004064 arylesterase activity(GO:0004064)
0.0 0.2 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.2 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.0 0.5 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.1 GO:0033149 FFAT motif binding(GO:0033149)
0.0 0.2 GO:0008240 tripeptidyl-peptidase activity(GO:0008240)
0.0 0.2 GO:0005047 signal recognition particle binding(GO:0005047)
0.0 0.2 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.0 0.2 GO:0050309 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.0 0.4 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 0.5 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.1 GO:1902122 chenodeoxycholic acid binding(GO:1902122)
0.0 0.4 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.1 GO:0032427 GBD domain binding(GO:0032427)
0.0 0.2 GO:0004982 N-formyl peptide receptor activity(GO:0004982)
0.0 0.2 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.0 0.2 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.0 0.9 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.7 GO:0031005 filamin binding(GO:0031005)
0.0 0.1 GO:0031177 acyl binding(GO:0000035) phosphopantetheine binding(GO:0031177)
0.0 0.7 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.1 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.0 0.1 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.0 0.2 GO:0052739 phosphatidylserine 1-acylhydrolase activity(GO:0052739)
0.0 1.5 GO:0008009 chemokine activity(GO:0008009)
0.0 0.1 GO:0034046 poly(G) binding(GO:0034046)
0.0 0.3 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.9 GO:0016769 transferase activity, transferring nitrogenous groups(GO:0016769)
0.0 0.5 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.0 0.4 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 0.2 GO:0003998 acylphosphatase activity(GO:0003998)
0.0 0.1 GO:0031531 thyrotropin-releasing hormone receptor binding(GO:0031531)
0.0 0.1 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
0.0 0.1 GO:0008124 4-alpha-hydroxytetrahydrobiopterin dehydratase activity(GO:0008124)
0.0 0.2 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.0 1.4 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.2 GO:0030021 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.0 0.4 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.3 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.1 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.0 0.3 GO:0004568 chitinase activity(GO:0004568)
0.0 0.1 GO:0030272 5-formyltetrahydrofolate cyclo-ligase activity(GO:0030272)
0.0 2.1 GO:0003774 motor activity(GO:0003774)
0.0 0.1 GO:0015057 thrombin receptor activity(GO:0015057)
0.0 0.1 GO:0004963 follicle-stimulating hormone receptor activity(GO:0004963)
0.0 0.3 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 0.1 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.0 1.3 GO:0003682 chromatin binding(GO:0003682)
0.0 0.1 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.4 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.0 0.1 GO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282)
0.0 0.9 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.0 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.0 0.2 GO:0032027 myosin light chain binding(GO:0032027)
0.0 0.2 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.0 0.1 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.0 0.2 GO:0008142 oxysterol binding(GO:0008142)
0.0 0.2 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.1 GO:0047150 betaine-homocysteine S-methyltransferase activity(GO:0047150)
0.0 0.3 GO:0004000 adenosine deaminase activity(GO:0004000)
0.0 0.1 GO:0030337 DNA polymerase processivity factor activity(GO:0030337)
0.0 1.0 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.2 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.1 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.0 0.1 GO:0031711 angiotensin type I receptor activity(GO:0001596) bradykinin receptor binding(GO:0031711)
0.0 0.3 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.5 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.1 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.0 0.6 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.1 GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.0 0.3 GO:0005539 glycosaminoglycan binding(GO:0005539)
0.0 2.0 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.3 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.8 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.1 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0 0.6 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.2 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.1 GO:0030109 HLA-B specific inhibitory MHC class I receptor activity(GO:0030109)
0.0 0.3 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.5 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 0.2 GO:0004303 estradiol 17-beta-dehydrogenase activity(GO:0004303)
0.0 0.2 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.1 GO:0047751 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765) cholestenone 5-alpha-reductase activity(GO:0047751)
0.0 0.6 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.1 GO:0004522 ribonuclease A activity(GO:0004522)
0.0 0.2 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.0 0.1 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.4 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.3 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.1 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.2 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.2 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.0 0.1 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.1 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0 0.0 GO:0016532 superoxide dismutase copper chaperone activity(GO:0016532)
0.0 0.1 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.0 0.1 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0 0.2 GO:0001055 RNA polymerase II activity(GO:0001055)
0.0 0.1 GO:0001093 TFIIB-class transcription factor binding(GO:0001093)
0.0 0.2 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.0 GO:0052590 sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
0.0 0.5 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.1 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
0.0 0.2 GO:0042609 CD4 receptor binding(GO:0042609)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 ST_ADRENERGIC Adrenergic Pathway
0.0 2.1 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.0 0.7 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling
0.0 1.9 PID_RHOA_REG_PATHWAY Regulation of RhoA activity
0.0 1.1 PID_RAC1_REG_PATHWAY Regulation of RAC1 activity
0.0 4.4 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.2 PID_IL5_PATHWAY IL5-mediated signaling events
0.0 1.2 PID_ARF6_TRAFFICKING_PATHWAY Arf6 trafficking events
0.0 0.2 PID_IL1_PATHWAY IL1-mediated signaling events
0.0 0.2 PID_S1P_S1P4_PATHWAY S1P4 pathway
0.0 0.0 ST_GAQ_PATHWAY G alpha q Pathway
0.0 0.6 PID_ERBB4_PATHWAY ErbB4 signaling events
0.0 1.7 PID_CMYB_PATHWAY C-MYB transcription factor network
0.0 0.6 PID_TRAIL_PATHWAY TRAIL signaling pathway
0.0 0.7 PID_FRA_PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.1 PID_THROMBIN_PAR4_PATHWAY PAR4-mediated thrombin signaling events
0.0 0.3 PID_HDAC_CLASSIII_PATHWAY Signaling events mediated by HDAC Class III
0.0 1.1 PID_AR_PATHWAY Coregulation of Androgen receptor activity

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 15.7 REACTOME_ETHANOL_OXIDATION Genes involved in Ethanol oxidation
0.2 3.7 REACTOME_RECYCLING_OF_BILE_ACIDS_AND_SALTS Genes involved in Recycling of bile acids and salts
0.2 3.8 REACTOME_XENOBIOTICS Genes involved in Xenobiotics
0.2 4.9 REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 3.3 REACTOME_TRANSLOCATION_OF_ZAP_70_TO_IMMUNOLOGICAL_SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.1 6.5 REACTOME_COMPLEMENT_CASCADE Genes involved in Complement cascade
0.1 1.2 REACTOME_ENDOSOMAL_VACUOLAR_PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.1 1.0 REACTOME_DIGESTION_OF_DIETARY_CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.1 1.1 REACTOME_LIPID_DIGESTION_MOBILIZATION_AND_TRANSPORT Genes involved in Lipid digestion, mobilization, and transport
0.1 3.1 REACTOME_CHONDROITIN_SULFATE_BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.1 1.5 REACTOME_ACYL_CHAIN_REMODELLING_OF_PS Genes involved in Acyl chain remodelling of PS
0.1 1.6 REACTOME_GLUCURONIDATION Genes involved in Glucuronidation
0.1 1.3 REACTOME_SYNTHESIS_OF_VERY_LONG_CHAIN_FATTY_ACYL_COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.8 REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 1.5 REACTOME_BETA_DEFENSINS Genes involved in Beta defensins
0.0 0.8 REACTOME_P2Y_RECEPTORS Genes involved in P2Y receptors
0.0 1.5 REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 1.3 REACTOME_INHIBITION_OF_VOLTAGE_GATED_CA2_CHANNELS_VIA_GBETA_GAMMA_SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.7 REACTOME_HDL_MEDIATED_LIPID_TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 2.9 REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 1.5 REACTOME_IRON_UPTAKE_AND_TRANSPORT Genes involved in Iron uptake and transport
0.0 0.6 REACTOME_PROLACTIN_RECEPTOR_SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.5 REACTOME_SYNTHESIS_SECRETION_AND_DEACYLATION_OF_GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.1 REACTOME_BINDING_AND_ENTRY_OF_HIV_VIRION Genes involved in Binding and entry of HIV virion
0.0 0.5 REACTOME_N_GLYCAN_ANTENNAE_ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.8 REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX Genes involved in Degradation of the extracellular matrix
0.0 1.0 REACTOME_GLUTATHIONE_CONJUGATION Genes involved in Glutathione conjugation
0.0 0.6 REACTOME_EXTRINSIC_PATHWAY_FOR_APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.2 REACTOME_NFKB_ACTIVATION_THROUGH_FADD_RIP1_PATHWAY_MEDIATED_BY_CASPASE_8_AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0 0.2 REACTOME_CELL_SURFACE_INTERACTIONS_AT_THE_VASCULAR_WALL Genes involved in Cell surface interactions at the vascular wall
0.0 0.6 REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.2 REACTOME_VIRAL_MESSENGER_RNA_SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 0.4 REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.4 REACTOME_CYTOSOLIC_SULFONATION_OF_SMALL_MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 1.3 REACTOME_AMYLOIDS Genes involved in Amyloids
0.0 0.2 REACTOME_HOMOLOGOUS_RECOMBINATION_REPAIR_OF_REPLICATION_INDEPENDENT_DOUBLE_STRAND_BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.2 REACTOME_REVERSIBLE_HYDRATION_OF_CARBON_DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.4 REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.2 REACTOME_GLUCOSE_TRANSPORT Genes involved in Glucose transport
0.0 0.5 REACTOME_EXTENSION_OF_TELOMERES Genes involved in Extension of Telomeres
0.0 0.7 REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.4 REACTOME_POST_TRANSLATIONAL_MODIFICATION_SYNTHESIS_OF_GPI_ANCHORED_PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0 0.2 REACTOME_INHIBITION_OF_INSULIN_SECRETION_BY_ADRENALINE_NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 0.3 REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.4 REACTOME_THE_ROLE_OF_NEF_IN_HIV1_REPLICATION_AND_DISEASE_PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0 0.1 REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.0 0.4 REACTOME_RNA_POL_III_TRANSCRIPTION_TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.0 0.5 REACTOME_CGMP_EFFECTS Genes involved in cGMP effects
0.0 0.2 REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.6 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.0 0.3 REACTOME_AMINE_DERIVED_HORMONES Genes involved in Amine-derived hormones