Motif ID: FUBP1

Z-value: 0.440


Transcription factors associated with FUBP1:

Gene SymbolEntrez IDGene Name
FUBP1 ENSG00000162613.12 FUBP1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
FUBP1hg19_v2_chr1_-_78444776_78444800-0.405.4e-02Click!


Activity profile for motif FUBP1.

activity profile for motif FUBP1


Sorted Z-values histogram for motif FUBP1

Sorted Z-values for motif FUBP1



Network of associatons between targets according to the STRING database.



First level regulatory network of FUBP1

PNG image of the network

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Top targets:


Showing 1 to 20 of 194 entries
PromoterScoreRefseqGene SymbolGene Name
chr10_-_105845674 0.951 ENST00000353479.5
ENST00000369733.3
 COL17A1

collagen, type XVII, alpha 1

chr2_-_72375167 0.594 ENST00000001146.2
 CYP26B1
cytochrome P450, family 26, subfamily B, polypeptide 1
chr15_-_89764929 0.593 ENST00000268125.5
 RLBP1
retinaldehyde binding protein 1
chr4_-_48136217 0.590 ENST00000264316.4
 TXK
TXK tyrosine kinase
chr2_-_216300784 0.554 ENST00000421182.1
ENST00000432072.2
ENST00000323926.6
ENST00000336916.4
ENST00000357867.4
ENST00000359671.1
ENST00000346544.3
ENST00000345488.5
ENST00000357009.2
ENST00000446046.1
ENST00000356005.4
ENST00000443816.1
ENST00000426059.1
ENST00000354785.4
 FN1













fibronectin 1













chr4_-_48082192 0.449 ENST00000507351.1
 TXK
TXK tyrosine kinase
chr12_-_91576561 0.442 ENST00000547568.2
ENST00000552962.1
 DCN

decorin

chr1_-_43855444 0.418 ENST00000372455.4
 MED8
mediator complex subunit 8
chr1_+_205682497 0.386 ENST00000598338.1
 AC119673.1
AC119673.1
chr9_-_110251836 0.379 ENST00000374672.4
 KLF4
Kruppel-like factor 4 (gut)
chr4_-_140544386 0.369 ENST00000561977.1
 RP11-308D13.3
RP11-308D13.3
chr15_-_34628951 0.355 ENST00000397707.2
ENST00000560611.1
 SLC12A6

solute carrier family 12 (potassium/chloride transporter), member 6

chr12_+_57522258 0.340 ENST00000553277.1
ENST00000243077.3
 LRP1

low density lipoprotein receptor-related protein 1

chr11_-_66964638 0.334 ENST00000444002.2
 AP001885.1
AP001885.1
chr9_+_75766763 0.332 ENST00000456643.1
ENST00000415424.1
 ANXA1

annexin A1

chr21_+_30502806 0.324 ENST00000399928.1
ENST00000399926.1
 MAP3K7CL

MAP3K7 C-terminal like

chr11_-_107590383 0.321 ENST00000525934.1
ENST00000531293.1
 SLN

sarcolipin

chr12_-_91576429 0.312 ENST00000552145.1
ENST00000546745.1
 DCN

decorin

chr6_+_37897735 0.310 ENST00000373389.5
 ZFAND3
zinc finger, AN1-type domain 3
chr2_-_65593784 0.303 ENST00000443619.2
 SPRED2
sprouty-related, EVH1 domain containing 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 60 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 1.0 GO:0060332 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.0 1.0 GO:0031581 hemidesmosome assembly(GO:0031581)
0.3 0.8 GO:2001037 tongue muscle cell differentiation(GO:0035981) positive regulation of skeletal muscle fiber differentiation(GO:1902811) regulation of tongue muscle cell differentiation(GO:2001035) positive regulation of tongue muscle cell differentiation(GO:2001037)
0.0 0.8 GO:0051901 positive regulation of mitochondrial depolarization(GO:0051901)
0.2 0.6 GO:0052047 interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047)
0.0 0.6 GO:0006776 vitamin A metabolic process(GO:0006776)
0.2 0.5 GO:0097254 renal tubular secretion(GO:0097254)
0.1 0.4 GO:0014740 negative regulation of muscle hyperplasia(GO:0014740)
0.1 0.4 GO:0071477 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.0 0.4 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.1 0.3 GO:0014839 myoblast migration involved in skeletal muscle regeneration(GO:0014839)
0.1 0.3 GO:1901876 regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877)
0.1 0.3 GO:0046671 negative regulation of cellular pH reduction(GO:0032848) CD8-positive, alpha-beta T cell lineage commitment(GO:0043375) negative regulation of retinal cell programmed cell death(GO:0046671)
0.0 0.3 GO:0001757 somite specification(GO:0001757) sclerotome development(GO:0061056)
0.0 0.3 GO:0050957 equilibrioception(GO:0050957)
0.0 0.3 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.0 0.3 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.3 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0 0.3 GO:0032695 negative regulation of interleukin-12 production(GO:0032695)
0.1 0.2 GO:0010652 regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652)

Gene overrepresentation in cellular_component category:

Showing 1 to 13 of 13 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.1 GO:0030056 hemidesmosome(GO:0030056)
0.1 0.8 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.6 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.4 GO:0016592 mediator complex(GO:0016592)
0.0 0.3 GO:0031313 extrinsic component of external side of plasma membrane(GO:0031232) extrinsic component of endosome membrane(GO:0031313)
0.0 0.3 GO:0005916 fascia adherens(GO:0005916)
0.0 0.3 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.2 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.0 0.2 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 0.2 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 0.2 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.1 GO:0033565 ESCRT-0 complex(GO:0033565)
0.0 0.1 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 41 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.1 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.2 0.8 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.1 0.6 GO:0005502 11-cis retinal binding(GO:0005502)
0.0 0.6 GO:0016504 peptidase activator activity(GO:0016504)
0.0 0.5 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.1 0.4 GO:0004382 guanosine-diphosphatase activity(GO:0004382)
0.1 0.4 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.0 0.4 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.4 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.1 0.3 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 0.3 GO:0050436 microfibril binding(GO:0050436)
0.0 0.3 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 0.3 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.3 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.3 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.1 0.2 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
0.0 0.2 GO:0030226 apolipoprotein receptor activity(GO:0030226) lipoprotein transporter activity(GO:0042954)
0.0 0.2 GO:0086075 gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075)
0.0 0.2 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 0.2 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)

Gene overrepresentation in C2:CP category:

Showing 1 to 4 of 4 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.0 NABA_COLLAGENS Genes encoding collagen proteins
0.0 1.0 PID_FRA_PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.6 PID_INTEGRIN5_PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.4 SA_FAS_SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 13 of 13 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.0 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.0 0.8 REACTOME_CS_DS_DEGRADATION Genes involved in CS/DS degradation
0.0 0.8 REACTOME_CYTOCHROME_P450_ARRANGED_BY_SUBSTRATE_TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.6 REACTOME_GRB2_SOS_PROVIDES_LINKAGE_TO_MAPK_SIGNALING_FOR_INTERGRINS_ Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 0.5 REACTOME_ORGANIC_CATION_ANION_ZWITTERION_TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.5 REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.4 REACTOME_SYNTHESIS_SECRETION_AND_DEACYLATION_OF_GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.4 REACTOME_EFFECTS_OF_PIP2_HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.3 REACTOME_ACTIVATION_OF_BH3_ONLY_PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.2 REACTOME_NEGATIVE_REGULATION_OF_THE_PI3K_AKT_NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.2 REACTOME_CALNEXIN_CALRETICULIN_CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.2 REACTOME_GAP_JUNCTION_DEGRADATION Genes involved in Gap junction degradation
0.0 0.1 REACTOME_ABACAVIR_TRANSPORT_AND_METABOLISM Genes involved in Abacavir transport and metabolism