Motif ID: GAGGUAG
Z-value: 1.247
Mature miRNA associated with seed GAGGUAG:
Top targets:
Showing 1 to 20 of 200 entries
Gene overrepresentation in biological_process category:
Showing 1 to 20 of 227 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.6 | 3.8 | GO:0009082 | branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099) |
| 0.6 | 3.2 | GO:0090402 | oncogene-induced cell senescence(GO:0090402) |
| 0.1 | 2.9 | GO:0042744 | hydrogen peroxide catabolic process(GO:0042744) |
| 0.1 | 2.8 | GO:0071481 | cellular response to X-ray(GO:0071481) |
| 0.7 | 2.7 | GO:0045065 | cytotoxic T cell differentiation(GO:0045065) |
| 0.2 | 2.6 | GO:0015693 | magnesium ion transport(GO:0015693) |
| 0.2 | 2.6 | GO:0060019 | radial glial cell differentiation(GO:0060019) |
| 0.2 | 2.3 | GO:0032119 | sequestering of zinc ion(GO:0032119) |
| 0.2 | 2.3 | GO:0038063 | collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) |
| 0.2 | 2.1 | GO:0001542 | ovulation from ovarian follicle(GO:0001542) |
| 0.0 | 2.1 | GO:0030574 | collagen catabolic process(GO:0030574) |
| 0.0 | 2.1 | GO:0042035 | regulation of cytokine biosynthetic process(GO:0042035) |
| 0.7 | 2.0 | GO:1903966 | monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966) |
| 0.7 | 2.0 | GO:1904298 | positive regulation of neutrophil degranulation(GO:0043315) cellular response to gravity(GO:0071258) positive regulation of neutrophil activation(GO:1902565) regulation of transcytosis(GO:1904298) positive regulation of transcytosis(GO:1904300) regulation of maternal process involved in parturition(GO:1904301) positive regulation of maternal process involved in parturition(GO:1904303) response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine(GO:1904316) cellular response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine(GO:1904317) |
| 0.7 | 2.0 | GO:0002605 | negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581) negative regulation of dendritic cell antigen processing and presentation(GO:0002605) |
| 0.7 | 2.0 | GO:1903225 | negative regulation of endodermal cell differentiation(GO:1903225) |
| 0.0 | 2.0 | GO:0006501 | C-terminal protein lipidation(GO:0006501) |
| 0.2 | 1.9 | GO:0030643 | cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502) |
| 0.1 | 1.9 | GO:0035970 | peptidyl-threonine dephosphorylation(GO:0035970) |
| 0.5 | 1.8 | GO:0014846 | esophagus smooth muscle contraction(GO:0014846) |
Gene overrepresentation in cellular_component category:
Showing 1 to 20 of 87 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.6 | 4.8 | GO:0005587 | collagen type IV trimer(GO:0005587) |
| 0.3 | 3.2 | GO:0035985 | senescence-associated heterochromatin focus(GO:0035985) |
| 0.0 | 3.2 | GO:0060170 | ciliary membrane(GO:0060170) |
| 0.0 | 2.9 | GO:0005795 | Golgi stack(GO:0005795) |
| 0.5 | 2.8 | GO:0097129 | cyclin D2-CDK4 complex(GO:0097129) |
| 0.0 | 2.2 | GO:0070821 | tertiary granule membrane(GO:0070821) |
| 0.7 | 2.0 | GO:0005588 | collagen type V trimer(GO:0005588) |
| 0.2 | 2.0 | GO:0005577 | fibrinogen complex(GO:0005577) |
| 0.3 | 1.8 | GO:0030121 | AP-1 adaptor complex(GO:0030121) |
| 0.6 | 1.7 | GO:0005900 | oncostatin-M receptor complex(GO:0005900) |
| 0.5 | 1.5 | GO:0070557 | PCNA-p21 complex(GO:0070557) |
| 0.4 | 1.5 | GO:0048237 | rough endoplasmic reticulum lumen(GO:0048237) |
| 0.0 | 1.5 | GO:0030173 | integral component of Golgi membrane(GO:0030173) |
| 0.0 | 1.5 | GO:0033116 | endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116) |
| 0.1 | 1.4 | GO:0005583 | fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643) |
| 0.0 | 1.3 | GO:0097228 | sperm principal piece(GO:0097228) |
| 0.2 | 1.2 | GO:0005971 | ribonucleoside-diphosphate reductase complex(GO:0005971) |
| 0.2 | 1.2 | GO:0032133 | chromosome passenger complex(GO:0032133) |
| 0.1 | 1.2 | GO:0005847 | mRNA cleavage and polyadenylation specificity factor complex(GO:0005847) |
| 0.0 | 1.2 | GO:0019005 | SCF ubiquitin ligase complex(GO:0019005) |
Gene overrepresentation in molecular_function category:
Showing 1 to 20 of 143 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 7.3 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
| 0.6 | 3.8 | GO:0052654 | branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656) |
| 0.0 | 3.0 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
| 0.6 | 2.9 | GO:0005152 | interleukin-1 receptor antagonist activity(GO:0005152) |
| 0.2 | 2.9 | GO:0017017 | MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) |
| 0.1 | 2.9 | GO:0048027 | mRNA 5'-UTR binding(GO:0048027) |
| 0.1 | 2.9 | GO:0005164 | tumor necrosis factor receptor binding(GO:0005164) |
| 0.1 | 2.5 | GO:0015095 | magnesium ion transmembrane transporter activity(GO:0015095) |
| 0.6 | 2.4 | GO:0035501 | MH1 domain binding(GO:0035501) |
| 0.0 | 2.4 | GO:0051015 | actin filament binding(GO:0051015) |
| 0.1 | 2.3 | GO:0004185 | serine-type carboxypeptidase activity(GO:0004185) |
| 0.0 | 2.1 | GO:0001205 | transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205) |
| 0.7 | 2.0 | GO:0070052 | collagen V binding(GO:0070052) |
| 0.4 | 2.0 | GO:0016215 | stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215) |
| 0.4 | 2.0 | GO:0004992 | platelet activating factor receptor activity(GO:0004992) |
| 0.6 | 1.9 | GO:0008330 | protein tyrosine/threonine phosphatase activity(GO:0008330) |
| 0.6 | 1.9 | GO:0047389 | glycerophosphocholine phosphodiesterase activity(GO:0047389) |
| 0.3 | 1.7 | GO:0004924 | oncostatin-M receptor activity(GO:0004924) |
| 0.1 | 1.7 | GO:0016500 | protein-hormone receptor activity(GO:0016500) |
| 0.0 | 1.7 | GO:0008565 | protein transporter activity(GO:0008565) |
Gene overrepresentation in C2:CP category:
Showing 1 to 20 of 29 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 8.0 | NABA_COLLAGENS | Genes encoding collagen proteins |
| 0.0 | 5.0 | NABA_ECM_REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
| 0.0 | 4.2 | PID_MYC_ACTIV_PATHWAY | Validated targets of C-MYC transcriptional activation |
| 0.1 | 3.9 | PID_IL2_STAT5_PATHWAY | IL2 signaling events mediated by STAT5 |
| 0.0 | 2.8 | PID_INTEGRIN3_PATHWAY | Beta3 integrin cell surface interactions |
| 0.0 | 2.8 | NABA_ECM_GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
| 0.0 | 2.6 | PID_HIF1_TFPATHWAY | HIF-1-alpha transcription factor network |
| 0.0 | 2.5 | PID_ER_NONGENOMIC_PATHWAY | Plasma membrane estrogen receptor signaling |
| 0.2 | 2.3 | SA_G2_AND_M_PHASES | Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition. |
| 0.0 | 2.3 | PID_P53_DOWNSTREAM_PATHWAY | Direct p53 effectors |
| 0.0 | 2.1 | PID_CD8_TCR_PATHWAY | TCR signaling in naïve CD8+ T cells |
| 0.0 | 1.8 | PID_E2F_PATHWAY | E2F transcription factor network |
| 0.0 | 1.5 | SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES | Genes related to regulation of the actin cytoskeleton |
| 0.0 | 1.4 | PID_P38_ALPHA_BETA_PATHWAY | Regulation of p38-alpha and p38-beta |
| 0.0 | 1.3 | SA_MMP_CYTOKINE_CONNECTION | Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix. |
| 0.0 | 1.3 | ST_WNT_BETA_CATENIN_PATHWAY | Wnt/beta-catenin Pathway |
| 0.0 | 1.1 | PID_TOLL_ENDOGENOUS_PATHWAY | Endogenous TLR signaling |
| 0.0 | 1.1 | PID_TELOMERASE_PATHWAY | Regulation of Telomerase |
| 0.0 | 0.9 | PID_ARF6_PATHWAY | Arf6 signaling events |
| 0.0 | 0.8 | ST_ERK1_ERK2_MAPK_PATHWAY | ERK1/ERK2 MAPK Pathway |
Gene overrepresentation in C2:CP:REACTOME category:
Showing 1 to 20 of 55 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 8.2 | REACTOME_COLLAGEN_FORMATION | Genes involved in Collagen formation |
| 0.1 | 5.9 | REACTOME_G1_PHASE | Genes involved in G1 Phase |
| 0.0 | 3.9 | REACTOME_DIABETES_PATHWAYS | Genes involved in Diabetes pathways |
| 0.1 | 3.6 | REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM | Genes involved in Branched-chain amino acid catabolism |
| 0.2 | 2.7 | REACTOME_ERKS_ARE_INACTIVATED | Genes involved in ERKs are inactivated |
| 0.0 | 2.2 | REACTOME_INTERFERON_GAMMA_SIGNALING | Genes involved in Interferon gamma signaling |
| 0.0 | 2.2 | REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS | Genes involved in Integrin cell surface interactions |
| 0.1 | 1.9 | REACTOME_G1_S_SPECIFIC_TRANSCRIPTION | Genes involved in G1/S-Specific Transcription |
| 0.1 | 1.8 | REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION | Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression |
| 0.0 | 1.8 | REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS | Genes involved in O-linked glycosylation of mucins |
| 0.1 | 1.4 | REACTOME_SYNTHESIS_OF_PE | Genes involved in Synthesis of PE |
| 0.0 | 1.4 | REACTOME_GLUCOSE_TRANSPORT | Genes involved in Glucose transport |
| 0.1 | 1.3 | REACTOME_IL_6_SIGNALING | Genes involved in Interleukin-6 signaling |
| 0.0 | 1.2 | REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING | Genes involved in Insulin Synthesis and Processing |
| 0.0 | 1.1 | REACTOME_SHC1_EVENTS_IN_ERBB4_SIGNALING | Genes involved in SHC1 events in ERBB4 signaling |
| 0.0 | 1.1 | REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES | Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates |
| 0.0 | 1.1 | REACTOME_RECYCLING_PATHWAY_OF_L1 | Genes involved in Recycling pathway of L1 |
| 0.0 | 0.9 | REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS | Genes involved in Na+/Cl- dependent neurotransmitter transporters |
| 0.1 | 0.8 | REACTOME_APOBEC3G_MEDIATED_RESISTANCE_TO_HIV1_INFECTION | Genes involved in APOBEC3G mediated resistance to HIV-1 infection |
| 0.0 | 0.8 | REACTOME_CTLA4_INHIBITORY_SIGNALING | Genes involved in CTLA4 inhibitory signaling |
