Motif ID: GATA1_GATA4
Z-value: 0.916
Transcription factors associated with GATA1_GATA4:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
GATA1 | ENSG00000102145.9 | GATA1 |
GATA4 | ENSG00000136574.13 | GATA4 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
GATA1 | hg19_v2_chrX_+_48644962_48644983 | 0.57 | 3.5e-03 | Click! |
GATA4 | hg19_v2_chr8_+_11534462_11534475 | 0.48 | 1.6e-02 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.6 | 4.5 | GO:0002784 | regulation of antimicrobial peptide production(GO:0002784) regulation of antibacterial peptide production(GO:0002786) |
0.6 | 3.5 | GO:0038172 | interleukin-33-mediated signaling pathway(GO:0038172) |
0.5 | 1.6 | GO:0046521 | sphingoid catabolic process(GO:0046521) |
0.4 | 1.3 | GO:0036058 | filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060) |
0.3 | 1.0 | GO:0060585 | regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585) |
0.3 | 0.9 | GO:0032911 | negative regulation of transforming growth factor beta1 production(GO:0032911) |
0.3 | 1.5 | GO:0071477 | hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477) |
0.3 | 1.2 | GO:0045875 | negative regulation of sister chromatid cohesion(GO:0045875) |
0.3 | 2.9 | GO:0070574 | cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574) |
0.2 | 1.0 | GO:1900425 | negative regulation of defense response to bacterium(GO:1900425) |
0.2 | 1.4 | GO:0051012 | microtubule sliding(GO:0051012) |
0.2 | 0.9 | GO:0009822 | alkaloid catabolic process(GO:0009822) |
0.2 | 0.6 | GO:0042450 | arginine biosynthetic process via ornithine(GO:0042450) response to biotin(GO:0070781) |
0.2 | 2.0 | GO:1903944 | regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944) |
0.2 | 0.7 | GO:0071894 | histone H2B conserved C-terminal lysine ubiquitination(GO:0071894) |
0.2 | 0.7 | GO:0090362 | positive regulation of platelet-derived growth factor production(GO:0090362) |
0.2 | 5.1 | GO:0009235 | cobalamin metabolic process(GO:0009235) |
0.2 | 0.9 | GO:0099590 | neurotransmitter receptor internalization(GO:0099590) |
0.2 | 0.5 | GO:0007057 | spindle assembly involved in female meiosis I(GO:0007057) positive regulation of oocyte maturation(GO:1900195) |
0.2 | 0.5 | GO:1901301 | regulation of cargo loading into COPII-coated vesicle(GO:1901301) |
0.2 | 0.7 | GO:0042418 | epinephrine biosynthetic process(GO:0042418) |
0.2 | 1.7 | GO:0051597 | response to methylmercury(GO:0051597) |
0.2 | 0.8 | GO:0045918 | negative regulation of cytolysis(GO:0045918) |
0.2 | 0.8 | GO:0061767 | negative regulation of lung blood pressure(GO:0061767) |
0.1 | 0.6 | GO:0003366 | cell-matrix adhesion involved in ameboidal cell migration(GO:0003366) |
0.1 | 0.6 | GO:0014846 | esophagus smooth muscle contraction(GO:0014846) |
0.1 | 0.1 | GO:0002652 | regulation of tolerance induction dependent upon immune response(GO:0002652) |
0.1 | 0.9 | GO:1903300 | negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300) |
0.1 | 0.9 | GO:0061343 | cell adhesion involved in heart morphogenesis(GO:0061343) |
0.1 | 0.4 | GO:0045578 | negative regulation of B cell differentiation(GO:0045578) |
0.1 | 0.4 | GO:0006742 | NADP catabolic process(GO:0006742) pyridine nucleotide catabolic process(GO:0019364) |
0.1 | 0.4 | GO:0010949 | negative regulation of intestinal phytosterol absorption(GO:0010949) negative regulation of intestinal cholesterol absorption(GO:0045796) intestinal phytosterol absorption(GO:0060752) negative regulation of intestinal lipid absorption(GO:1904730) |
0.1 | 0.7 | GO:0061143 | alveolar primary septum development(GO:0061143) |
0.1 | 0.4 | GO:1901069 | guanosine-containing compound catabolic process(GO:1901069) |
0.1 | 0.7 | GO:0060332 | positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335) |
0.1 | 3.0 | GO:0071481 | cellular response to X-ray(GO:0071481) |
0.1 | 0.5 | GO:0071344 | diphosphate metabolic process(GO:0071344) |
0.1 | 0.5 | GO:0030311 | poly-N-acetyllactosamine biosynthetic process(GO:0030311) |
0.1 | 0.4 | GO:1901350 | cell-cell signaling involved in cell-cell junction organization(GO:1901350) |
0.1 | 0.3 | GO:0032877 | positive regulation of DNA endoreduplication(GO:0032877) |
0.1 | 0.3 | GO:0045726 | positive regulation of integrin biosynthetic process(GO:0045726) |
0.1 | 0.3 | GO:0003218 | cardiac left ventricle formation(GO:0003218) |
0.1 | 0.5 | GO:0033490 | cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490) |
0.1 | 0.4 | GO:0045872 | positive regulation of rhodopsin gene expression(GO:0045872) |
0.1 | 0.7 | GO:0042866 | pyruvate biosynthetic process(GO:0042866) |
0.1 | 0.3 | GO:0044179 | cytolysis by symbiont of host cells(GO:0001897) hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331) |
0.1 | 0.3 | GO:0018874 | benzoate metabolic process(GO:0018874) |
0.1 | 1.3 | GO:0019532 | oxalate transport(GO:0019532) |
0.1 | 0.6 | GO:1904879 | positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879) |
0.1 | 0.2 | GO:0016103 | diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653) |
0.1 | 0.5 | GO:0055014 | atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014) |
0.1 | 0.7 | GO:0072205 | metanephric collecting duct development(GO:0072205) |
0.1 | 0.4 | GO:0007538 | primary sex determination(GO:0007538) |
0.1 | 0.4 | GO:0036269 | swimming behavior(GO:0036269) |
0.1 | 0.9 | GO:0072656 | maintenance of protein location in mitochondrion(GO:0072656) |
0.1 | 0.9 | GO:2000138 | positive regulation of cell proliferation involved in heart morphogenesis(GO:2000138) |
0.1 | 0.2 | GO:0098746 | fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746) |
0.1 | 0.2 | GO:2000015 | regulation of determination of dorsal identity(GO:2000015) |
0.1 | 0.3 | GO:1903215 | negative regulation of protein targeting to mitochondrion(GO:1903215) |
0.1 | 0.4 | GO:1900383 | regulation of synaptic plasticity by receptor localization to synapse(GO:1900383) |
0.1 | 0.9 | GO:0034196 | acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197) |
0.1 | 1.1 | GO:0043320 | natural killer cell degranulation(GO:0043320) |
0.1 | 0.3 | GO:0007499 | ectoderm and mesoderm interaction(GO:0007499) |
0.1 | 1.5 | GO:0044241 | lipid digestion(GO:0044241) |
0.1 | 1.1 | GO:0045657 | positive regulation of monocyte differentiation(GO:0045657) |
0.1 | 0.3 | GO:0050928 | negative regulation of positive chemotaxis(GO:0050928) |
0.1 | 0.2 | GO:0040010 | positive regulation of growth rate(GO:0040010) regulation of gastric mucosal blood circulation(GO:1904344) positive regulation of gastric mucosal blood circulation(GO:1904346) gastric mucosal blood circulation(GO:1990768) |
0.1 | 0.2 | GO:1903487 | regulation of lactation(GO:1903487) |
0.1 | 0.2 | GO:2000523 | regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525) |
0.1 | 0.6 | GO:2001300 | lipoxin metabolic process(GO:2001300) |
0.1 | 9.0 | GO:0070268 | cornification(GO:0070268) |
0.1 | 0.4 | GO:0034421 | post-translational protein acetylation(GO:0034421) |
0.1 | 0.2 | GO:0001694 | histamine biosynthetic process(GO:0001694) |
0.1 | 0.4 | GO:2000543 | positive regulation of gastrulation(GO:2000543) |
0.1 | 1.0 | GO:0023041 | neuronal signal transduction(GO:0023041) negative regulation of axon regeneration(GO:0048681) |
0.1 | 0.8 | GO:0052696 | flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697) |
0.1 | 0.2 | GO:0036023 | limb joint morphogenesis(GO:0036022) embryonic skeletal limb joint morphogenesis(GO:0036023) |
0.1 | 0.2 | GO:0090235 | regulation of metaphase plate congression(GO:0090235) |
0.1 | 0.8 | GO:0046325 | negative regulation of glucose import(GO:0046325) |
0.1 | 0.2 | GO:0045226 | extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379) renal water absorption(GO:0070295) |
0.1 | 2.5 | GO:0006607 | NLS-bearing protein import into nucleus(GO:0006607) |
0.1 | 0.6 | GO:0034378 | chylomicron assembly(GO:0034378) |
0.1 | 0.2 | GO:0008050 | female courtship behavior(GO:0008050) |
0.1 | 0.6 | GO:0090050 | positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050) |
0.1 | 0.2 | GO:0070171 | negative regulation of tooth mineralization(GO:0070171) |
0.1 | 0.3 | GO:1904274 | tricellular tight junction assembly(GO:1904274) |
0.1 | 0.2 | GO:2001027 | negative regulation of endothelial cell chemotaxis(GO:2001027) |
0.1 | 0.2 | GO:0002408 | myeloid dendritic cell chemotaxis(GO:0002408) |
0.1 | 0.3 | GO:0015811 | L-cystine transport(GO:0015811) |
0.1 | 0.3 | GO:2000504 | positive regulation of blood vessel remodeling(GO:2000504) |
0.1 | 0.2 | GO:0031100 | organ regeneration(GO:0031100) |
0.1 | 0.2 | GO:0001692 | histamine metabolic process(GO:0001692) |
0.1 | 0.2 | GO:0002322 | B cell proliferation involved in immune response(GO:0002322) |
0.1 | 0.9 | GO:0045603 | positive regulation of endothelial cell differentiation(GO:0045603) |
0.1 | 0.2 | GO:0033326 | cerebrospinal fluid secretion(GO:0033326) |
0.1 | 0.4 | GO:0061113 | pancreas morphogenesis(GO:0061113) |
0.1 | 0.4 | GO:0022027 | interkinetic nuclear migration(GO:0022027) |
0.1 | 0.2 | GO:0046013 | regulation of T cell homeostatic proliferation(GO:0046013) |
0.0 | 0.2 | GO:1990523 | bone regeneration(GO:1990523) |
0.0 | 0.1 | GO:0002027 | regulation of heart rate(GO:0002027) |
0.0 | 0.9 | GO:0030277 | maintenance of gastrointestinal epithelium(GO:0030277) |
0.0 | 0.1 | GO:0044340 | canonical Wnt signaling pathway involved in regulation of cell proliferation(GO:0044340) |
0.0 | 0.2 | GO:1903691 | positive regulation of wound healing, spreading of epidermal cells(GO:1903691) |
0.0 | 0.1 | GO:1901379 | regulation of potassium ion transmembrane transport(GO:1901379) |
0.0 | 0.4 | GO:0070197 | meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240) |
0.0 | 0.2 | GO:0034372 | very-low-density lipoprotein particle remodeling(GO:0034372) regulation of high-density lipoprotein particle assembly(GO:0090107) |
0.0 | 0.7 | GO:1904778 | regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778) |
0.0 | 0.1 | GO:0007518 | myoblast fate determination(GO:0007518) |
0.0 | 0.1 | GO:0061386 | closure of optic fissure(GO:0061386) |
0.0 | 0.2 | GO:1904217 | regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) positive regulation of serine C-palmitoyltransferase activity(GO:1904222) |
0.0 | 0.4 | GO:0051694 | pointed-end actin filament capping(GO:0051694) |
0.0 | 0.1 | GO:0001808 | negative regulation of type IV hypersensitivity(GO:0001808) |
0.0 | 0.6 | GO:0032836 | glomerular basement membrane development(GO:0032836) |
0.0 | 2.1 | GO:0050690 | regulation of defense response to virus by virus(GO:0050690) |
0.0 | 0.4 | GO:0042541 | hemoglobin biosynthetic process(GO:0042541) |
0.0 | 0.2 | GO:0006196 | AMP catabolic process(GO:0006196) |
0.0 | 0.7 | GO:0051988 | regulation of attachment of spindle microtubules to kinetochore(GO:0051988) |
0.0 | 0.2 | GO:0071802 | negative regulation of podosome assembly(GO:0071802) |
0.0 | 0.5 | GO:0038171 | cannabinoid signaling pathway(GO:0038171) |
0.0 | 0.4 | GO:0032341 | aldosterone metabolic process(GO:0032341) aldosterone biosynthetic process(GO:0032342) |
0.0 | 0.3 | GO:0045048 | protein insertion into ER membrane(GO:0045048) |
0.0 | 0.2 | GO:0071400 | cellular response to oleic acid(GO:0071400) |
0.0 | 0.2 | GO:0098707 | ferrous iron import(GO:0070627) ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707) |
0.0 | 0.9 | GO:1902857 | positive regulation of nonmotile primary cilium assembly(GO:1902857) |
0.0 | 3.5 | GO:0050829 | defense response to Gram-negative bacterium(GO:0050829) |
0.0 | 0.3 | GO:1903385 | regulation of homophilic cell adhesion(GO:1903385) |
0.0 | 0.1 | GO:0003285 | septum secundum development(GO:0003285) |
0.0 | 0.3 | GO:0001867 | complement activation, lectin pathway(GO:0001867) |
0.0 | 0.7 | GO:0043517 | positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517) |
0.0 | 0.8 | GO:0002089 | lens morphogenesis in camera-type eye(GO:0002089) |
0.0 | 0.2 | GO:0021797 | forebrain anterior/posterior pattern specification(GO:0021797) |
0.0 | 0.2 | GO:0051342 | regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342) negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344) |
0.0 | 0.2 | GO:0051933 | amino acid neurotransmitter reuptake(GO:0051933) glutamate reuptake(GO:0051935) |
0.0 | 0.7 | GO:0035855 | megakaryocyte development(GO:0035855) |
0.0 | 0.1 | GO:0051873 | killing by host of symbiont cells(GO:0051873) |
0.0 | 0.4 | GO:0042761 | very long-chain fatty acid biosynthetic process(GO:0042761) |
0.0 | 2.6 | GO:0003254 | regulation of membrane depolarization(GO:0003254) |
0.0 | 0.3 | GO:0055091 | phospholipid homeostasis(GO:0055091) positive regulation of cholesterol homeostasis(GO:2000189) |
0.0 | 1.5 | GO:0046627 | negative regulation of insulin receptor signaling pathway(GO:0046627) negative regulation of cellular response to insulin stimulus(GO:1900077) |
0.0 | 0.1 | GO:1901895 | regulation of the force of heart contraction by cardiac conduction(GO:0086092) regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877) negative regulation of calcium-transporting ATPase activity(GO:1901895) regulation of calcium ion import into sarcoplasmic reticulum(GO:1902080) negative regulation of calcium ion import into sarcoplasmic reticulum(GO:1902081) |
0.0 | 0.2 | GO:0035105 | sterol regulatory element binding protein import into nucleus(GO:0035105) |
0.0 | 0.2 | GO:0044878 | mitotic cytokinesis checkpoint(GO:0044878) |
0.0 | 0.1 | GO:0031247 | actin rod assembly(GO:0031247) |
0.0 | 0.9 | GO:0019433 | triglyceride catabolic process(GO:0019433) |
0.0 | 0.3 | GO:0060215 | primitive hemopoiesis(GO:0060215) |
0.0 | 0.8 | GO:0031581 | hemidesmosome assembly(GO:0031581) |
0.0 | 0.2 | GO:0010724 | regulation of definitive erythrocyte differentiation(GO:0010724) |
0.0 | 0.5 | GO:0019371 | cyclooxygenase pathway(GO:0019371) |
0.0 | 0.1 | GO:0006097 | glyoxylate cycle(GO:0006097) |
0.0 | 1.4 | GO:0033046 | negative regulation of sister chromatid segregation(GO:0033046) negative regulation of mitotic sister chromatid segregation(GO:0033048) negative regulation of mitotic sister chromatid separation(GO:2000816) |
0.0 | 0.2 | GO:0019556 | histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606) |
0.0 | 0.2 | GO:0033384 | geranyl diphosphate metabolic process(GO:0033383) geranyl diphosphate biosynthetic process(GO:0033384) farnesyl diphosphate biosynthetic process(GO:0045337) |
0.0 | 1.2 | GO:0072488 | ammonium transmembrane transport(GO:0072488) |
0.0 | 0.3 | GO:0018401 | peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) |
0.0 | 0.5 | GO:0032703 | negative regulation of interleukin-2 production(GO:0032703) |
0.0 | 0.7 | GO:0006646 | phosphatidylethanolamine biosynthetic process(GO:0006646) |
0.0 | 0.4 | GO:0032780 | negative regulation of ATPase activity(GO:0032780) |
0.0 | 0.2 | GO:0006657 | CDP-choline pathway(GO:0006657) |
0.0 | 0.3 | GO:0034312 | diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512) |
0.0 | 0.5 | GO:0045618 | positive regulation of keratinocyte differentiation(GO:0045618) |
0.0 | 0.3 | GO:0002051 | osteoblast fate commitment(GO:0002051) |
0.0 | 0.3 | GO:0070970 | interleukin-2 secretion(GO:0070970) |
0.0 | 0.3 | GO:0010629 | negative regulation of gene expression(GO:0010629) |
0.0 | 0.4 | GO:0098609 | cell-cell adhesion(GO:0098609) |
0.0 | 0.4 | GO:0048227 | plasma membrane to endosome transport(GO:0048227) |
0.0 | 0.2 | GO:0038129 | directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842) ERBB3 signaling pathway(GO:0038129) |
0.0 | 0.1 | GO:0002378 | immunoglobulin biosynthetic process(GO:0002378) |
0.0 | 0.3 | GO:0035873 | lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) |
0.0 | 0.2 | GO:0036444 | calcium ion transmembrane import into mitochondrion(GO:0036444) |
0.0 | 0.1 | GO:0042538 | hyperosmotic salinity response(GO:0042538) |
0.0 | 0.1 | GO:1904717 | excitatory chemical synaptic transmission(GO:0098976) regulation of AMPA glutamate receptor clustering(GO:1904717) positive regulation of AMPA glutamate receptor clustering(GO:1904719) |
0.0 | 0.1 | GO:2001240 | negative regulation of signal transduction in absence of ligand(GO:1901099) regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001239) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240) |
0.0 | 0.3 | GO:0030916 | otic vesicle formation(GO:0030916) |
0.0 | 0.0 | GO:0002215 | defense response to nematode(GO:0002215) |
0.0 | 0.1 | GO:0008627 | intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627) |
0.0 | 0.4 | GO:0001946 | lymphangiogenesis(GO:0001946) |
0.0 | 0.3 | GO:0043383 | negative T cell selection(GO:0043383) |
0.0 | 0.1 | GO:2000360 | negative regulation of binding of sperm to zona pellucida(GO:2000360) |
0.0 | 0.2 | GO:2001206 | positive regulation of osteoclast development(GO:2001206) |
0.0 | 0.2 | GO:0099566 | regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566) |
0.0 | 0.2 | GO:0030091 | protein repair(GO:0030091) |
0.0 | 0.7 | GO:1900027 | regulation of ruffle assembly(GO:1900027) |
0.0 | 0.2 | GO:0017183 | peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183) |
0.0 | 0.9 | GO:0000188 | inactivation of MAPK activity(GO:0000188) |
0.0 | 0.2 | GO:0043950 | positive regulation of cAMP-mediated signaling(GO:0043950) |
0.0 | 0.1 | GO:1900005 | positive regulation of serine-type endopeptidase activity(GO:1900005) negative regulation of sperm motility(GO:1901318) positive regulation of serine-type peptidase activity(GO:1902573) |
0.0 | 0.2 | GO:0070933 | histone H4 deacetylation(GO:0070933) |
0.0 | 0.1 | GO:0061107 | seminal vesicle development(GO:0061107) |
0.0 | 0.1 | GO:0032468 | Golgi calcium ion homeostasis(GO:0032468) |
0.0 | 0.4 | GO:0003334 | keratinocyte development(GO:0003334) |
0.0 | 0.2 | GO:0015886 | heme transport(GO:0015886) |
0.0 | 0.3 | GO:0050860 | negative regulation of T cell receptor signaling pathway(GO:0050860) |
0.0 | 0.2 | GO:0033632 | regulation of cell-cell adhesion mediated by integrin(GO:0033632) |
0.0 | 0.2 | GO:0043249 | erythrocyte maturation(GO:0043249) |
0.0 | 0.2 | GO:0048387 | negative regulation of retinoic acid receptor signaling pathway(GO:0048387) |
0.0 | 0.1 | GO:0020027 | hemoglobin metabolic process(GO:0020027) |
0.0 | 0.2 | GO:0000395 | mRNA 5'-splice site recognition(GO:0000395) |
0.0 | 0.2 | GO:1902035 | positive regulation of hematopoietic stem cell proliferation(GO:1902035) |
0.0 | 0.1 | GO:0071955 | recycling endosome to Golgi transport(GO:0071955) |
0.0 | 0.1 | GO:0033364 | mast cell secretory granule organization(GO:0033364) |
0.0 | 0.0 | GO:0097156 | fasciculation of motor neuron axon(GO:0097156) |
0.0 | 0.2 | GO:0030213 | hyaluronan biosynthetic process(GO:0030213) |
0.0 | 0.5 | GO:0006825 | copper ion transport(GO:0006825) |
0.0 | 0.7 | GO:0045687 | positive regulation of glial cell differentiation(GO:0045687) |
0.0 | 0.1 | GO:0002175 | protein localization to paranode region of axon(GO:0002175) |
0.0 | 1.4 | GO:0001570 | vasculogenesis(GO:0001570) |
0.0 | 0.5 | GO:0002230 | positive regulation of defense response to virus by host(GO:0002230) |
0.0 | 0.1 | GO:1902161 | transepithelial water transport(GO:0035377) positive regulation of cyclic nucleotide-gated ion channel activity(GO:1902161) |
0.0 | 0.2 | GO:0006108 | malate metabolic process(GO:0006108) |
0.0 | 0.1 | GO:0006452 | translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905) |
0.0 | 0.1 | GO:0044829 | positive regulation by host of viral genome replication(GO:0044829) |
0.0 | 0.2 | GO:0002098 | tRNA wobble uridine modification(GO:0002098) |
0.0 | 0.3 | GO:0033189 | response to vitamin A(GO:0033189) |
0.0 | 0.1 | GO:1904158 | axonemal central apparatus assembly(GO:1904158) |
0.0 | 0.4 | GO:0001556 | oocyte maturation(GO:0001556) |
0.0 | 0.1 | GO:0060737 | prostate epithelial cord elongation(GO:0060523) prostate gland morphogenetic growth(GO:0060737) |
0.0 | 0.5 | GO:0043403 | skeletal muscle tissue regeneration(GO:0043403) |
0.0 | 0.2 | GO:0050884 | neuromuscular process controlling posture(GO:0050884) |
0.0 | 0.7 | GO:0006739 | NADP metabolic process(GO:0006739) |
0.0 | 1.2 | GO:0007585 | respiratory gaseous exchange(GO:0007585) |
0.0 | 0.1 | GO:0060613 | fat pad development(GO:0060613) |
0.0 | 0.2 | GO:0019388 | galactose catabolic process(GO:0019388) |
0.0 | 0.2 | GO:0006054 | N-acetylneuraminate metabolic process(GO:0006054) |
0.0 | 0.4 | GO:0008535 | respiratory chain complex IV assembly(GO:0008535) |
0.0 | 0.1 | GO:0080009 | mRNA methylation(GO:0080009) |
0.0 | 0.8 | GO:0007566 | embryo implantation(GO:0007566) |
0.0 | 0.2 | GO:0001765 | membrane raft assembly(GO:0001765) |
0.0 | 0.2 | GO:0098828 | positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828) |
0.0 | 2.8 | GO:0007173 | epidermal growth factor receptor signaling pathway(GO:0007173) |
0.0 | 0.4 | GO:0046716 | muscle cell cellular homeostasis(GO:0046716) |
0.0 | 0.1 | GO:0001865 | NK T cell differentiation(GO:0001865) |
0.0 | 0.3 | GO:0007095 | mitotic G2 DNA damage checkpoint(GO:0007095) |
0.0 | 0.1 | GO:0032430 | positive regulation of phospholipase A2 activity(GO:0032430) |
0.0 | 0.1 | GO:0015991 | ATP hydrolysis coupled proton transport(GO:0015991) ATP hydrolysis coupled transmembrane transport(GO:0090662) |
0.0 | 0.2 | GO:0071688 | striated muscle myosin thick filament assembly(GO:0071688) |
0.0 | 0.1 | GO:0002316 | follicular B cell differentiation(GO:0002316) |
0.0 | 0.1 | GO:0031284 | positive regulation of guanylate cyclase activity(GO:0031284) |
0.0 | 0.5 | GO:1904893 | negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893) |
0.0 | 0.2 | GO:0035641 | locomotory exploration behavior(GO:0035641) |
0.0 | 0.1 | GO:0002643 | regulation of tolerance induction(GO:0002643) |
0.0 | 0.1 | GO:0006704 | glucocorticoid biosynthetic process(GO:0006704) |
0.0 | 0.9 | GO:0006968 | cellular defense response(GO:0006968) |
0.0 | 0.0 | GO:0014738 | regulation of muscle hyperplasia(GO:0014738) |
0.0 | 0.4 | GO:0001501 | skeletal system development(GO:0001501) |
0.0 | 0.2 | GO:0090161 | Golgi ribbon formation(GO:0090161) |
0.0 | 0.0 | GO:0044778 | meiotic DNA integrity checkpoint(GO:0044778) |
0.0 | 0.2 | GO:1901841 | regulation of high voltage-gated calcium channel activity(GO:1901841) |
0.0 | 0.2 | GO:0070208 | protein heterotrimerization(GO:0070208) |
0.0 | 0.2 | GO:0051639 | actin filament network formation(GO:0051639) |
0.0 | 0.3 | GO:0030866 | cortical actin cytoskeleton organization(GO:0030866) |
0.0 | 0.1 | GO:0009957 | epidermal cell fate specification(GO:0009957) |
0.0 | 0.4 | GO:0006376 | mRNA splice site selection(GO:0006376) |
0.0 | 0.1 | GO:1903027 | regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959) regulation of opsonization(GO:1903027) |
0.0 | 0.3 | GO:0097421 | liver regeneration(GO:0097421) |
0.0 | 0.3 | GO:0016338 | calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.6 | 4.5 | GO:0097209 | epidermal lamellar body(GO:0097209) |
0.5 | 3.0 | GO:0097129 | cyclin D2-CDK4 complex(GO:0097129) |
0.2 | 1.0 | GO:0048237 | rough endoplasmic reticulum lumen(GO:0048237) |
0.1 | 0.6 | GO:0034669 | integrin alpha4-beta7 complex(GO:0034669) |
0.1 | 0.6 | GO:0016222 | procollagen-proline 4-dioxygenase complex(GO:0016222) |
0.1 | 0.7 | GO:0097149 | centralspindlin complex(GO:0097149) |
0.1 | 0.4 | GO:0043511 | inhibin complex(GO:0043511) inhibin A complex(GO:0043512) |
0.1 | 0.5 | GO:0001674 | female germ cell nucleus(GO:0001674) |
0.1 | 0.5 | GO:0032937 | SREBP-SCAP-Insig complex(GO:0032937) |
0.1 | 1.4 | GO:0042105 | alpha-beta T cell receptor complex(GO:0042105) |
0.1 | 0.6 | GO:0070876 | SOSS complex(GO:0070876) |
0.1 | 0.3 | GO:0020005 | symbiont-containing vacuole(GO:0020003) symbiont-containing vacuole membrane(GO:0020005) other organism cytoplasm(GO:0097679) |
0.1 | 0.4 | GO:0097442 | CA3 pyramidal cell dendrite(GO:0097442) |
0.1 | 0.9 | GO:0031314 | extrinsic component of mitochondrial inner membrane(GO:0031314) |
0.1 | 0.8 | GO:0005610 | laminin-5 complex(GO:0005610) |
0.1 | 0.8 | GO:0031466 | Cul5-RING ubiquitin ligase complex(GO:0031466) |
0.1 | 0.8 | GO:0071144 | SMAD2-SMAD3 protein complex(GO:0071144) |
0.1 | 2.0 | GO:0031265 | CD95 death-inducing signaling complex(GO:0031265) ripoptosome(GO:0097342) |
0.1 | 1.2 | GO:0033093 | Weibel-Palade body(GO:0033093) |
0.1 | 5.8 | GO:0001533 | cornified envelope(GO:0001533) |
0.1 | 0.6 | GO:0005587 | collagen type IV trimer(GO:0005587) |
0.1 | 0.5 | GO:0000015 | phosphopyruvate hydratase complex(GO:0000015) |
0.1 | 0.4 | GO:0070695 | FHF complex(GO:0070695) |
0.1 | 0.9 | GO:0008091 | spectrin(GO:0008091) |
0.1 | 1.1 | GO:0031362 | anchored component of external side of plasma membrane(GO:0031362) |
0.0 | 0.2 | GO:0060200 | clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201) |
0.0 | 0.2 | GO:0035370 | UBC13-UEV1A complex(GO:0035370) |
0.0 | 1.0 | GO:0097431 | mitotic spindle pole(GO:0097431) |
0.0 | 0.2 | GO:0038038 | G-protein coupled receptor homodimeric complex(GO:0038038) |
0.0 | 1.1 | GO:0031229 | integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) |
0.0 | 0.6 | GO:1990454 | L-type voltage-gated calcium channel complex(GO:1990454) |
0.0 | 0.2 | GO:1990246 | uniplex complex(GO:1990246) |
0.0 | 0.1 | GO:0034365 | discoidal high-density lipoprotein particle(GO:0034365) |
0.0 | 0.9 | GO:0036020 | endolysosome membrane(GO:0036020) |
0.0 | 3.4 | GO:1904724 | tertiary granule lumen(GO:1904724) |
0.0 | 0.3 | GO:1990393 | Cul7-RING ubiquitin ligase complex(GO:0031467) 3M complex(GO:1990393) |
0.0 | 0.6 | GO:0097225 | sperm midpiece(GO:0097225) |
0.0 | 0.4 | GO:0043190 | ATP-binding cassette (ABC) transporter complex(GO:0043190) |
0.0 | 0.3 | GO:0016012 | sarcoglycan complex(GO:0016012) |
0.0 | 0.2 | GO:0005899 | insulin receptor complex(GO:0005899) |
0.0 | 0.8 | GO:0042627 | chylomicron(GO:0042627) |
0.0 | 0.6 | GO:0032045 | guanyl-nucleotide exchange factor complex(GO:0032045) |
0.0 | 0.3 | GO:0071438 | invadopodium membrane(GO:0071438) |
0.0 | 0.1 | GO:0036025 | protein C inhibitor-TMPRSS7 complex(GO:0036024) protein C inhibitor-TMPRSS11E complex(GO:0036025) protein C inhibitor-PLAT complex(GO:0036026) protein C inhibitor-PLAU complex(GO:0036027) protein C inhibitor-thrombin complex(GO:0036028) protein C inhibitor-KLK3 complex(GO:0036029) protein C inhibitor-plasma kallikrein complex(GO:0036030) serine protease inhibitor complex(GO:0097180) protein C inhibitor-coagulation factor V complex(GO:0097181) protein C inhibitor-coagulation factor Xa complex(GO:0097182) protein C inhibitor-coagulation factor XI complex(GO:0097183) |
0.0 | 2.6 | GO:0072686 | mitotic spindle(GO:0072686) |
0.0 | 1.0 | GO:0097228 | sperm principal piece(GO:0097228) |
0.0 | 0.1 | GO:1990716 | axonemal central apparatus(GO:1990716) |
0.0 | 0.7 | GO:0031105 | septin complex(GO:0031105) |
0.0 | 0.3 | GO:0000347 | THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445) |
0.0 | 0.4 | GO:0031618 | nuclear pericentric heterochromatin(GO:0031618) |
0.0 | 0.3 | GO:0000940 | condensed chromosome outer kinetochore(GO:0000940) |
0.0 | 0.8 | GO:0005921 | gap junction(GO:0005921) |
0.0 | 0.1 | GO:0000275 | mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) |
0.0 | 0.7 | GO:0031430 | M band(GO:0031430) |
0.0 | 0.2 | GO:0005638 | lamin filament(GO:0005638) |
0.0 | 0.3 | GO:0071141 | SMAD protein complex(GO:0071141) |
0.0 | 0.3 | GO:0034663 | endoplasmic reticulum chaperone complex(GO:0034663) |
0.0 | 1.2 | GO:0016235 | aggresome(GO:0016235) |
0.0 | 0.4 | GO:0030426 | growth cone(GO:0030426) |
0.0 | 0.4 | GO:0031672 | A band(GO:0031672) |
0.0 | 0.3 | GO:0033270 | paranode region of axon(GO:0033270) |
0.0 | 0.3 | GO:0097512 | cardiac myofibril(GO:0097512) |
0.0 | 0.4 | GO:0001891 | phagocytic cup(GO:0001891) |
0.0 | 0.1 | GO:0061617 | MICOS complex(GO:0061617) |
0.0 | 0.2 | GO:1990712 | HFE-transferrin receptor complex(GO:1990712) |
0.0 | 0.0 | GO:0030895 | apolipoprotein B mRNA editing enzyme complex(GO:0030895) |
0.0 | 1.7 | GO:0005604 | basement membrane(GO:0005604) |
0.0 | 0.3 | GO:0002102 | podosome(GO:0002102) |
0.0 | 0.1 | GO:0072357 | PTW/PP1 phosphatase complex(GO:0072357) |
0.0 | 1.7 | GO:0001669 | acrosomal vesicle(GO:0001669) |
0.0 | 0.4 | GO:0042629 | mast cell granule(GO:0042629) |
0.0 | 0.1 | GO:0097449 | astrocyte projection(GO:0097449) |
0.0 | 2.5 | GO:0043197 | dendritic spine(GO:0043197) |
0.0 | 0.2 | GO:0042622 | photoreceptor outer segment membrane(GO:0042622) |
0.0 | 0.1 | GO:0045179 | apical cortex(GO:0045179) |
0.0 | 1.2 | GO:0070821 | tertiary granule membrane(GO:0070821) |
0.0 | 0.1 | GO:0031205 | endoplasmic reticulum Sec complex(GO:0031205) |
0.0 | 3.3 | GO:0009897 | external side of plasma membrane(GO:0009897) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.2 | 3.5 | GO:0002113 | interleukin-33 binding(GO:0002113) |
0.6 | 3.4 | GO:0042015 | interleukin-20 binding(GO:0042015) |
0.3 | 1.0 | GO:0038131 | neuregulin receptor activity(GO:0038131) |
0.3 | 0.9 | GO:0045518 | interleukin-22 receptor binding(GO:0045518) |
0.3 | 1.6 | GO:0017050 | sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050) |
0.3 | 0.8 | GO:0050613 | delta14-sterol reductase activity(GO:0050613) |
0.2 | 0.7 | GO:0004603 | phenylethanolamine N-methyltransferase activity(GO:0004603) |
0.2 | 1.3 | GO:0030197 | extracellular matrix constituent, lubricant activity(GO:0030197) |
0.2 | 0.6 | GO:0004464 | leukotriene-C4 synthase activity(GO:0004464) |
0.2 | 1.0 | GO:0031708 | endothelin B receptor binding(GO:0031708) |
0.2 | 0.6 | GO:0004769 | steroid delta-isomerase activity(GO:0004769) |
0.2 | 0.7 | GO:0004743 | pyruvate kinase activity(GO:0004743) |
0.2 | 2.9 | GO:0036312 | phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312) |
0.2 | 0.5 | GO:0003845 | 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845) |
0.2 | 0.5 | GO:0036134 | thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134) |
0.2 | 0.9 | GO:0070095 | fructose-6-phosphate binding(GO:0070095) |
0.2 | 0.8 | GO:0031962 | mineralocorticoid receptor binding(GO:0031962) |
0.2 | 1.1 | GO:0005157 | macrophage colony-stimulating factor receptor binding(GO:0005157) |
0.1 | 0.4 | GO:0016749 | 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749) |
0.1 | 0.7 | GO:0005499 | vitamin D binding(GO:0005499) |
0.1 | 0.4 | GO:0004507 | steroid 11-beta-monooxygenase activity(GO:0004507) corticosterone 18-monooxygenase activity(GO:0047783) |
0.1 | 0.7 | GO:0048248 | CXCR3 chemokine receptor binding(GO:0048248) |
0.1 | 1.3 | GO:0003960 | NADPH:quinone reductase activity(GO:0003960) |
0.1 | 1.5 | GO:0015379 | potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820) |
0.1 | 0.8 | GO:0004882 | androgen receptor activity(GO:0004882) |
0.1 | 0.5 | GO:0016262 | protein N-acetylglucosaminyltransferase activity(GO:0016262) |
0.1 | 0.7 | GO:0016316 | phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828) |
0.1 | 1.3 | GO:0019531 | oxalate transmembrane transporter activity(GO:0019531) |
0.1 | 0.5 | GO:0004949 | cannabinoid receptor activity(GO:0004949) |
0.1 | 0.8 | GO:0004340 | glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158) |
0.1 | 0.6 | GO:0008449 | N-acetylglucosamine-6-sulfatase activity(GO:0008449) |
0.1 | 0.5 | GO:0004427 | inorganic diphosphatase activity(GO:0004427) |
0.1 | 0.3 | GO:0030171 | voltage-gated proton channel activity(GO:0030171) |
0.1 | 0.6 | GO:0004656 | procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798) |
0.1 | 0.5 | GO:0045029 | UDP-activated nucleotide receptor activity(GO:0045029) |
0.1 | 0.5 | GO:0004634 | phosphopyruvate hydratase activity(GO:0004634) |
0.1 | 1.2 | GO:0045499 | chemorepellent activity(GO:0045499) |
0.1 | 2.1 | GO:0005001 | transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198) |
0.1 | 2.6 | GO:0005385 | zinc ion transmembrane transporter activity(GO:0005385) |
0.1 | 0.7 | GO:0004305 | ethanolamine kinase activity(GO:0004305) |
0.1 | 0.5 | GO:0060230 | lipoprotein lipase activator activity(GO:0060230) |
0.1 | 0.6 | GO:0086056 | voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056) |
0.1 | 0.2 | GO:0000035 | acyl binding(GO:0000035) |
0.1 | 0.7 | GO:0042731 | PH domain binding(GO:0042731) |
0.1 | 0.2 | GO:0031768 | ghrelin receptor binding(GO:0031768) |
0.1 | 0.3 | GO:0070180 | large ribosomal subunit rRNA binding(GO:0070180) |
0.1 | 0.7 | GO:0031419 | cobalamin binding(GO:0031419) |
0.1 | 2.0 | GO:0097200 | death receptor binding(GO:0005123) cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200) |
0.1 | 0.3 | GO:0017040 | ceramidase activity(GO:0017040) |
0.1 | 0.4 | GO:0070892 | lipoteichoic acid receptor activity(GO:0070892) |
0.1 | 1.1 | GO:0004896 | cytokine receptor activity(GO:0004896) |
0.1 | 0.2 | GO:0003943 | N-acetylgalactosamine-4-sulfatase activity(GO:0003943) |
0.1 | 0.5 | GO:0035174 | histone serine kinase activity(GO:0035174) |
0.1 | 0.3 | GO:0042610 | CD8 receptor binding(GO:0042610) |
0.1 | 0.3 | GO:0015184 | L-cystine transmembrane transporter activity(GO:0015184) |
0.1 | 0.2 | GO:0004087 | carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088) |
0.1 | 0.4 | GO:0034711 | inhibin binding(GO:0034711) |
0.1 | 0.4 | GO:0015485 | cholesterol binding(GO:0015485) |
0.1 | 0.9 | GO:0017017 | MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) |
0.1 | 0.4 | GO:0004468 | lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468) |
0.0 | 1.6 | GO:0005212 | structural constituent of eye lens(GO:0005212) |
0.0 | 0.2 | GO:0004998 | transferrin receptor activity(GO:0004998) |
0.0 | 0.9 | GO:0033612 | receptor serine/threonine kinase binding(GO:0033612) |
0.0 | 0.2 | GO:0010348 | lithium:proton antiporter activity(GO:0010348) |
0.0 | 0.2 | GO:0034186 | apolipoprotein A-I binding(GO:0034186) |
0.0 | 0.2 | GO:0050501 | hyaluronan synthase activity(GO:0050501) |
0.0 | 0.2 | GO:0033743 | peptide-methionine (R)-S-oxide reductase activity(GO:0033743) |
0.0 | 0.3 | GO:0044323 | retinoic acid-responsive element binding(GO:0044323) |
0.0 | 0.2 | GO:0030348 | syntaxin-3 binding(GO:0030348) |
0.0 | 0.1 | GO:0005497 | androgen binding(GO:0005497) |
0.0 | 0.2 | GO:0004105 | choline-phosphate cytidylyltransferase activity(GO:0004105) |
0.0 | 0.3 | GO:0030172 | troponin C binding(GO:0030172) |
0.0 | 0.9 | GO:0035615 | clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748) |
0.0 | 11.9 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
0.0 | 0.7 | GO:0015467 | G-protein activated inward rectifier potassium channel activity(GO:0015467) |
0.0 | 0.4 | GO:0004704 | NF-kappaB-inducing kinase activity(GO:0004704) |
0.0 | 0.3 | GO:0004321 | fatty-acyl-CoA synthase activity(GO:0004321) |
0.0 | 2.9 | GO:1990782 | protein tyrosine kinase binding(GO:1990782) |
0.0 | 0.3 | GO:0030618 | transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618) |
0.0 | 0.1 | GO:0051990 | isocitrate dehydrogenase (NADP+) activity(GO:0004450) (R)-2-hydroxyglutarate dehydrogenase activity(GO:0051990) |
0.0 | 0.2 | GO:0047623 | AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623) |
0.0 | 0.2 | GO:0004337 | dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337) |
0.0 | 0.3 | GO:0015129 | lactate transmembrane transporter activity(GO:0015129) |
0.0 | 0.2 | GO:0044547 | DNA topoisomerase binding(GO:0044547) |
0.0 | 1.5 | GO:0005504 | fatty acid binding(GO:0005504) |
0.0 | 1.0 | GO:0001972 | retinoic acid binding(GO:0001972) |
0.0 | 0.2 | GO:0004614 | phosphoglucomutase activity(GO:0004614) |
0.0 | 0.2 | GO:0098821 | BMP receptor activity(GO:0098821) |
0.0 | 0.2 | GO:0099583 | neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583) |
0.0 | 0.1 | GO:0004995 | tachykinin receptor activity(GO:0004995) |
0.0 | 0.2 | GO:0005134 | interleukin-2 receptor binding(GO:0005134) glycosphingolipid binding(GO:0043208) |
0.0 | 0.2 | GO:0070324 | thyroid hormone binding(GO:0070324) |
0.0 | 0.1 | GO:0001069 | regulatory region RNA binding(GO:0001069) |
0.0 | 0.0 | GO:0034597 | phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597) |
0.0 | 0.7 | GO:0004602 | glutathione peroxidase activity(GO:0004602) |
0.0 | 0.2 | GO:0008553 | hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553) |
0.0 | 0.4 | GO:0043522 | leucine zipper domain binding(GO:0043522) |
0.0 | 0.2 | GO:0016841 | ammonia-lyase activity(GO:0016841) |
0.0 | 0.1 | GO:0004514 | nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514) |
0.0 | 0.3 | GO:0097371 | MDM2/MDM4 family protein binding(GO:0097371) |
0.0 | 0.1 | GO:0030109 | HLA-B specific inhibitory MHC class I receptor activity(GO:0030109) |
0.0 | 0.4 | GO:0005243 | gap junction channel activity(GO:0005243) |
0.0 | 0.3 | GO:0019864 | IgG binding(GO:0019864) |
0.0 | 0.4 | GO:0008239 | dipeptidyl-peptidase activity(GO:0008239) |
0.0 | 0.1 | GO:0016715 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715) |
0.0 | 0.7 | GO:0000993 | RNA polymerase II core binding(GO:0000993) |
0.0 | 0.1 | GO:0016300 | tRNA (uracil) methyltransferase activity(GO:0016300) |
0.0 | 0.3 | GO:0050700 | CARD domain binding(GO:0050700) |
0.0 | 0.3 | GO:0005049 | nuclear export signal receptor activity(GO:0005049) |
0.0 | 1.6 | GO:0004869 | cysteine-type endopeptidase inhibitor activity(GO:0004869) |
0.0 | 0.4 | GO:0008190 | eukaryotic initiation factor 4E binding(GO:0008190) |
0.0 | 0.3 | GO:0043225 | anion transmembrane-transporting ATPase activity(GO:0043225) |
0.0 | 0.1 | GO:0048101 | calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101) |
0.0 | 0.2 | GO:0015232 | heme transporter activity(GO:0015232) |
0.0 | 0.5 | GO:0048027 | mRNA 5'-UTR binding(GO:0048027) |
0.0 | 0.1 | GO:0001596 | angiotensin type I receptor activity(GO:0001596) |
0.0 | 0.2 | GO:0047498 | calcium-dependent phospholipase A2 activity(GO:0047498) |
0.0 | 0.4 | GO:0031432 | titin binding(GO:0031432) |
0.0 | 0.4 | GO:0005523 | tropomyosin binding(GO:0005523) |
0.0 | 0.3 | GO:0008484 | sulfuric ester hydrolase activity(GO:0008484) |
0.0 | 2.9 | GO:0044325 | ion channel binding(GO:0044325) |
0.0 | 0.1 | GO:0047961 | glycine N-acyltransferase activity(GO:0047961) |
0.0 | 0.2 | GO:0022889 | L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889) |
0.0 | 0.7 | GO:0005160 | transforming growth factor beta receptor binding(GO:0005160) |
0.0 | 0.1 | GO:0042030 | ATPase inhibitor activity(GO:0042030) |
0.0 | 0.5 | GO:0005388 | calcium-transporting ATPase activity(GO:0005388) |
0.0 | 0.4 | GO:0019992 | diacylglycerol binding(GO:0019992) |
0.0 | 0.4 | GO:0002162 | dystroglycan binding(GO:0002162) |
0.0 | 0.1 | GO:0070051 | fibrinogen binding(GO:0070051) |
0.0 | 0.2 | GO:0005549 | odorant binding(GO:0005549) |
0.0 | 1.8 | GO:0005070 | SH3/SH2 adaptor activity(GO:0005070) |
0.0 | 0.4 | GO:0046875 | ephrin receptor binding(GO:0046875) |
0.0 | 0.5 | GO:0008198 | ferrous iron binding(GO:0008198) |
0.0 | 0.4 | GO:0015299 | solute:proton antiporter activity(GO:0015299) |
0.0 | 0.4 | GO:0042923 | neuropeptide binding(GO:0042923) |
0.0 | 1.4 | GO:0004197 | cysteine-type endopeptidase activity(GO:0004197) |
0.0 | 0.1 | GO:0008174 | mRNA methyltransferase activity(GO:0008174) |
0.0 | 14.1 | GO:0005198 | structural molecule activity(GO:0005198) |
0.0 | 0.1 | GO:0030250 | cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250) |
0.0 | 0.1 | GO:0070891 | lipoteichoic acid binding(GO:0070891) |
0.0 | 0.2 | GO:0016615 | malate dehydrogenase activity(GO:0016615) |
0.0 | 0.3 | GO:0005328 | neurotransmitter:sodium symporter activity(GO:0005328) |
0.0 | 0.0 | GO:0015265 | urea transmembrane transporter activity(GO:0015204) urea channel activity(GO:0015265) |
0.0 | 1.8 | GO:0005089 | Rho guanyl-nucleotide exchange factor activity(GO:0005089) |
0.0 | 0.3 | GO:0016638 | oxidoreductase activity, acting on the CH-NH2 group of donors(GO:0016638) |
0.0 | 0.1 | GO:0001665 | alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665) |
0.0 | 0.1 | GO:0001784 | phosphotyrosine binding(GO:0001784) |
0.0 | 0.1 | GO:0032190 | acrosin binding(GO:0032190) |
0.0 | 0.4 | GO:0015464 | acetylcholine receptor activity(GO:0015464) |
0.0 | 0.4 | GO:0051959 | dynein light intermediate chain binding(GO:0051959) |
0.0 | 0.2 | GO:0016500 | protein-hormone receptor activity(GO:0016500) |
0.0 | 1.5 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
0.0 | 0.1 | GO:0016936 | galactoside binding(GO:0016936) |
0.0 | 0.0 | GO:0015180 | L-alanine transmembrane transporter activity(GO:0015180) L-proline transmembrane transporter activity(GO:0015193) alanine transmembrane transporter activity(GO:0022858) |
0.0 | 0.8 | GO:0004715 | non-membrane spanning protein tyrosine kinase activity(GO:0004715) |
0.0 | 0.1 | GO:0038052 | RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052) |
0.0 | 0.3 | GO:0001871 | pattern binding(GO:0001871) polysaccharide binding(GO:0030247) |
0.0 | 0.2 | GO:0019841 | retinol binding(GO:0019841) |
0.0 | 0.1 | GO:0005119 | smoothened binding(GO:0005119) |
0.0 | 0.2 | GO:0016857 | racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857) |
0.0 | 0.6 | GO:0015459 | potassium channel regulator activity(GO:0015459) |
0.0 | 0.2 | GO:0051183 | vitamin transporter activity(GO:0051183) |
0.0 | 0.1 | GO:0070740 | tubulin-glutamic acid ligase activity(GO:0070740) |
0.0 | 0.1 | GO:0051185 | coenzyme transporter activity(GO:0051185) |
0.0 | 0.1 | GO:0030492 | hemoglobin binding(GO:0030492) |
Gene overrepresentation in C2:CP category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 2.0 | SA_FAS_SIGNALING | The TNF-type receptor Fas induces apoptosis on ligand binding. |
0.1 | 3.1 | PID_IL2_STAT5_PATHWAY | IL2 signaling events mediated by STAT5 |
0.1 | 1.6 | PID_S1P_META_PATHWAY | Sphingosine 1-phosphate (S1P) pathway |
0.0 | 4.9 | PID_TCR_PATHWAY | TCR signaling in naïve CD4+ T cells |
0.0 | 0.8 | PID_INTEGRIN4_PATHWAY | Alpha6 beta4 integrin-ligand interactions |
0.0 | 1.9 | PID_INSULIN_PATHWAY | Insulin Pathway |
0.0 | 1.9 | PID_INTEGRIN2_PATHWAY | Beta2 integrin cell surface interactions |
0.0 | 0.3 | PID_IL6_7_PATHWAY | IL6-mediated signaling events |
0.0 | 3.1 | PID_HIF1_TFPATHWAY | HIF-1-alpha transcription factor network |
0.0 | 0.6 | PID_INTEGRIN5_PATHWAY | Beta5 beta6 beta7 and beta8 integrin cell surface interactions |
0.0 | 1.0 | PID_ALK1_PATHWAY | ALK1 signaling events |
0.0 | 0.2 | ST_JAK_STAT_PATHWAY | Jak-STAT Pathway |
0.0 | 1.4 | PID_FCER1_PATHWAY | Fc-epsilon receptor I signaling in mast cells |
0.0 | 0.9 | PID_INTEGRIN_A9B1_PATHWAY | Alpha9 beta1 integrin signaling events |
0.0 | 1.3 | PID_FAK_PATHWAY | Signaling events mediated by focal adhesion kinase |
0.0 | 0.2 | SA_B_CELL_RECEPTOR_COMPLEXES | Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases. |
0.0 | 1.6 | PID_TAP63_PATHWAY | Validated transcriptional targets of TAp63 isoforms |
0.0 | 1.2 | PID_CDC42_REG_PATHWAY | Regulation of CDC42 activity |
0.0 | 1.2 | PID_HNF3B_PATHWAY | FOXA2 and FOXA3 transcription factor networks |
0.0 | 0.3 | PID_NEPHRIN_NEPH1_PATHWAY | Nephrin/Neph1 signaling in the kidney podocyte |
0.0 | 1.2 | PID_PLK1_PATHWAY | PLK1 signaling events |
0.0 | 0.6 | PID_INTEGRIN3_PATHWAY | Beta3 integrin cell surface interactions |
0.0 | 0.7 | PID_CXCR3_PATHWAY | CXCR3-mediated signaling events |
0.0 | 1.0 | PID_HES_HEY_PATHWAY | Notch-mediated HES/HEY network |
0.0 | 0.2 | PID_KIT_PATHWAY | Signaling events mediated by Stem cell factor receptor (c-Kit) |
0.0 | 0.8 | PID_FRA_PATHWAY | Validated transcriptional targets of AP1 family members Fra1 and Fra2 |
0.0 | 5.2 | NABA_ECM_REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
0.0 | 0.2 | PID_AR_NONGENOMIC_PATHWAY | Nongenotropic Androgen signaling |
0.0 | 0.5 | SIG_PIP3_SIGNALING_IN_CARDIAC_MYOCTES | Genes related to PIP3 signaling in cardiac myocytes |
0.0 | 0.1 | ST_PAC1_RECEPTOR_PATHWAY | PAC1 Receptor Pathway |
0.0 | 0.2 | ST_INTERLEUKIN_4_PATHWAY | Interleukin 4 (IL-4) Pathway |
0.0 | 0.3 | PID_ANGIOPOIETIN_RECEPTOR_PATHWAY | Angiopoietin receptor Tie2-mediated signaling |
0.0 | 0.4 | SA_MMP_CYTOKINE_CONNECTION | Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix. |
0.0 | 1.5 | PID_MYC_ACTIV_PATHWAY | Validated targets of C-MYC transcriptional activation |
0.0 | 0.5 | ST_WNT_BETA_CATENIN_PATHWAY | Wnt/beta-catenin Pathway |
0.0 | 0.4 | PID_PI3K_PLC_TRK_PATHWAY | Trk receptor signaling mediated by PI3K and PLC-gamma |
0.0 | 1.0 | PID_P75_NTR_PATHWAY | p75(NTR)-mediated signaling |
0.0 | 0.4 | PID_PTP1B_PATHWAY | Signaling events mediated by PTP1B |
0.0 | 5.0 | NABA_SECRETED_FACTORS | Genes encoding secreted soluble factors |
0.0 | 0.2 | ST_T_CELL_SIGNAL_TRANSDUCTION | T Cell Signal Transduction |
Gene overrepresentation in C2:CP:REACTOME category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 2.9 | REACTOME_ZINC_TRANSPORTERS | Genes involved in Zinc transporters |
0.1 | 0.7 | REACTOME_METAL_ION_SLC_TRANSPORTERS | Genes involved in Metal ion SLC transporters |
0.1 | 2.0 | REACTOME_EXTRINSIC_PATHWAY_FOR_APOPTOSIS | Genes involved in Extrinsic Pathway for Apoptosis |
0.1 | 2.5 | REACTOME_SIGNAL_REGULATORY_PROTEIN_SIRP_FAMILY_INTERACTIONS | Genes involved in Signal regulatory protein (SIRP) family interactions |
0.1 | 3.0 | REACTOME_THE_ROLE_OF_NEF_IN_HIV1_REPLICATION_AND_DISEASE_PATHOGENESIS | Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis |
0.1 | 1.3 | REACTOME_TIE2_SIGNALING | Genes involved in Tie2 Signaling |
0.0 | 0.8 | REACTOME_SIGNAL_ATTENUATION | Genes involved in Signal attenuation |
0.0 | 1.5 | REACTOME_CHOLESTEROL_BIOSYNTHESIS | Genes involved in Cholesterol biosynthesis |
0.0 | 3.1 | REACTOME_G1_PHASE | Genes involved in G1 Phase |
0.0 | 0.7 | REACTOME_DOPAMINE_NEUROTRANSMITTER_RELEASE_CYCLE | Genes involved in Dopamine Neurotransmitter Release Cycle |
0.0 | 1.6 | REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS | Genes involved in Association of TriC/CCT with target proteins during biosynthesis |
0.0 | 0.7 | REACTOME_SYNTHESIS_OF_PE | Genes involved in Synthesis of PE |
0.0 | 0.4 | REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS | Genes involved in Creation of C4 and C2 activators |
0.0 | 1.7 | REACTOME_GLUCOSE_TRANSPORT | Genes involved in Glucose transport |
0.0 | 0.5 | REACTOME_THE_ACTIVATION_OF_ARYLSULFATASES | Genes involved in The activation of arylsulfatases |
0.0 | 3.0 | REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL | Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell |
0.0 | 0.6 | REACTOME_INHIBITION_OF_INSULIN_SECRETION_BY_ADRENALINE_NORADRENALINE | Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline |
0.0 | 1.3 | REACTOME_GLYCOLYSIS | Genes involved in Glycolysis |
0.0 | 0.5 | REACTOME_CELL_SURFACE_INTERACTIONS_AT_THE_VASCULAR_WALL | Genes involved in Cell surface interactions at the vascular wall |
0.0 | 2.0 | REACTOME_LIPID_DIGESTION_MOBILIZATION_AND_TRANSPORT | Genes involved in Lipid digestion, mobilization, and transport |
0.0 | 0.5 | REACTOME_SYNTHESIS_OF_PIPS_AT_THE_EARLY_ENDOSOME_MEMBRANE | Genes involved in Synthesis of PIPs at the early endosome membrane |
0.0 | 1.0 | REACTOME_DOWNREGULATION_OF_TGF_BETA_RECEPTOR_SIGNALING | Genes involved in Downregulation of TGF-beta receptor signaling |
0.0 | 0.6 | REACTOME_GLUCURONIDATION | Genes involved in Glucuronidation |
0.0 | 1.6 | REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK | Genes involved in NRAGE signals death through JNK |
0.0 | 0.7 | REACTOME_G_ALPHA1213_SIGNALLING_EVENTS | Genes involved in G alpha (12/13) signalling events |
0.0 | 0.4 | REACTOME_APOPTOTIC_CLEAVAGE_OF_CELL_ADHESION_PROTEINS | Genes involved in Apoptotic cleavage of cell adhesion proteins |
0.0 | 0.4 | REACTOME_GAP_JUNCTION_ASSEMBLY | Genes involved in Gap junction assembly |
0.0 | 0.7 | REACTOME_INHIBITION_OF_VOLTAGE_GATED_CA2_CHANNELS_VIA_GBETA_GAMMA_SUBUNITS | Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits |
0.0 | 0.4 | REACTOME_HYALURONAN_METABOLISM | Genes involved in Hyaluronan metabolism |
0.0 | 1.8 | REACTOME_APC_C_CDH1_MEDIATED_DEGRADATION_OF_CDC20_AND_OTHER_APC_C_CDH1_TARGETED_PROTEINS_IN_LATE_MITOSIS_EARLY_G1 | Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 |
0.0 | 1.5 | REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY | Genes involved in Nuclear Receptor transcription pathway |
0.0 | 0.2 | REACTOME_G_PROTEIN_ACTIVATION | Genes involved in G-protein activation |
0.0 | 0.2 | REACTOME_PLATELET_ADHESION_TO_EXPOSED_COLLAGEN | Genes involved in Platelet Adhesion to exposed collagen |
0.0 | 0.5 | REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION | Genes involved in Cytosolic tRNA aminoacylation |
0.0 | 0.3 | REACTOME_ACTIVATION_OF_NF_KAPPAB_IN_B_CELLS | Genes involved in Activation of NF-kappaB in B Cells |
0.0 | 0.2 | REACTOME_ACYL_CHAIN_REMODELLING_OF_PS | Genes involved in Acyl chain remodelling of PS |
0.0 | 0.3 | REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX | Genes involved in Degradation of the extracellular matrix |
0.0 | 0.2 | REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS | Genes involved in Na+/Cl- dependent neurotransmitter transporters |
0.0 | 0.1 | REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_ATF6_ALPHA | Genes involved in Activation of Chaperone Genes by ATF6-alpha |
0.0 | 0.2 | REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS | Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors) |
0.0 | 2.1 | REACTOME_G_ALPHA_Q_SIGNALLING_EVENTS | Genes involved in G alpha (q) signalling events |