Motif ID: GAUUGUC

Z-value: 0.789


Mature miRNA associated with seed GAUUGUC:

NamemiRBase Accession
hsa-miR-219a-5p MIMAT0000276
hsa-miR-4782-3p MIMAT0019945
hsa-miR-6766-3p MIMAT0027433



Activity profile for motif GAUUGUC.

activity profile for motif GAUUGUC


Sorted Z-values histogram for motif GAUUGUC

Sorted Z-values for motif GAUUGUC



Network of associatons between targets according to the STRING database.



First level regulatory network of GAUUGUC

PNG image of the network

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Top targets:


Showing 1 to 20 of 195 entries
PromoterScoreRefseqGene SymbolGene Name
chr19_+_5914213 4.344 ENST00000222125.5
ENST00000452990.2
ENST00000588865.1
CAPS


calcyphosine


chr1_-_207119738 3.938 ENST00000356495.4
PIGR
polymeric immunoglobulin receptor
chr7_-_131241361 3.488 ENST00000378555.3
ENST00000322985.9
ENST00000541194.1
ENST00000537928.1
PODXL



podocalyxin-like



chr6_+_17281573 3.389 ENST00000379052.5
RBM24
RNA binding motif protein 24
chr4_+_75858290 3.245 ENST00000513238.1
PARM1
prostate androgen-regulated mucin-like protein 1
chr18_-_45663666 2.568 ENST00000535628.2
ZBTB7C
zinc finger and BTB domain containing 7C
chr5_+_50678921 1.754 ENST00000230658.7
ISL1
ISL LIM homeobox 1
chr1_+_244214577 1.623 ENST00000358704.4
ZBTB18
zinc finger and BTB domain containing 18
chr7_+_3340989 1.585 ENST00000404826.2
ENST00000389531.3
SDK1

sidekick cell adhesion molecule 1

chr16_-_19896220 1.575 ENST00000562469.1
ENST00000300571.2
GPRC5B

G protein-coupled receptor, family C, group 5, member B

chr17_+_68165657 1.492 ENST00000243457.3
KCNJ2
potassium inwardly-rectifying channel, subfamily J, member 2
chr19_-_14316980 1.447 ENST00000361434.3
ENST00000340736.6
LPHN1

latrophilin 1

chr4_-_105416039 1.305 ENST00000394767.2
CXXC4
CXXC finger protein 4
chr1_+_180601139 1.265 ENST00000367590.4
ENST00000367589.3
XPR1

xenotropic and polytropic retrovirus receptor 1

chr4_-_23891693 1.203 ENST00000264867.2
PPARGC1A
peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
chr17_+_31254892 1.181 ENST00000394642.3
ENST00000579849.1
TMEM98

transmembrane protein 98

chr15_+_57668695 1.171 ENST00000281282.5
CGNL1
cingulin-like 1
chr12_-_56652111 1.130 ENST00000267116.7
ANKRD52
ankyrin repeat domain 52
chr14_+_74111578 1.073 ENST00000554113.1
ENST00000555631.2
ENST00000553645.2
ENST00000311089.3
ENST00000555919.3
ENST00000554339.1
ENST00000554871.1
DNAL1






dynein, axonemal, light chain 1






chr1_-_115632035 1.016 ENST00000433172.1
ENST00000369514.2
ENST00000369516.2
ENST00000369515.2
TSPAN2



tetraspanin 2




Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 72 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.8 3.9 GO:0002415 immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
0.9 3.5 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.0 3.4 GO:0010830 regulation of myotube differentiation(GO:0010830)
0.1 3.2 GO:0051973 positive regulation of telomerase activity(GO:0051973)
0.2 2.6 GO:1903025 regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025)
0.6 1.8 GO:0021524 visceral motor neuron differentiation(GO:0021524) peripheral nervous system neuron axonogenesis(GO:0048936) cardiac cell fate determination(GO:0060913)
0.1 1.6 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
0.0 1.6 GO:0048148 behavioral response to cocaine(GO:0048148)
0.5 1.5 GO:0090076 relaxation of skeletal muscle(GO:0090076)
0.2 1.4 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.1 1.3 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.4 1.2 GO:1901860 positive regulation of mitochondrial DNA metabolic process(GO:1901860)
0.1 1.1 GO:0036158 outer dynein arm assembly(GO:0036158)
0.2 1.0 GO:0014005 microglia differentiation(GO:0014004) microglia development(GO:0014005)
0.1 1.0 GO:1900038 negative regulation of cellular response to hypoxia(GO:1900038)
0.0 1.0 GO:0061099 negative regulation of protein tyrosine kinase activity(GO:0061099)
0.3 0.8 GO:0045925 positive regulation of female receptivity(GO:0045925)
0.0 0.8 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.8 GO:0044803 multi-organism membrane organization(GO:0044803)
0.0 0.8 GO:0032728 positive regulation of interferon-beta production(GO:0032728)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 31 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 3.9 GO:0035577 azurophil granule membrane(GO:0035577)
0.4 3.5 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 1.8 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.1 1.6 GO:0097440 apical dendrite(GO:0097440)
0.0 1.4 GO:0043198 dendritic shaft(GO:0043198)
0.0 1.2 GO:0016459 myosin complex(GO:0016459)
0.1 1.1 GO:0036157 outer dynein arm(GO:0036157)
0.0 1.0 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 1.0 GO:0045171 intercellular bridge(GO:0045171)
0.2 0.7 GO:0019034 viral replication complex(GO:0019034)
0.0 0.7 GO:0048786 presynaptic active zone(GO:0048786)
0.1 0.6 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.5 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.4 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 0.4 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.4 GO:0071004 U2-type prespliceosome(GO:0071004)
0.0 0.3 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.0 0.3 GO:0042584 chromaffin granule membrane(GO:0042584)
0.0 0.3 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0 0.3 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 49 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 4.5 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.5 3.9 GO:0019763 immunoglobulin receptor activity(GO:0019763)
0.0 1.9 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.1 1.5 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.3 1.3 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.1 1.2 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 1.1 GO:0045504 dynein heavy chain binding(GO:0045504)
0.2 1.0 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.1 1.0 GO:0016403 dimethylargininase activity(GO:0016403)
0.1 0.7 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.1 0.7 GO:0008142 oxysterol binding(GO:0008142)
0.2 0.6 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.2 0.6 GO:0032184 SUMO polymer binding(GO:0032184)
0.1 0.6 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.0 0.6 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.6 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.6 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.6 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 0.5 GO:0042285 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.1 0.5 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)

Gene overrepresentation in C2:CP category:

Showing 1 to 9 of 9 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 3.3 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 2.9 PID_IL4_2PATHWAY IL4-mediated signaling events
0.0 1.2 PID_HDAC_CLASSIII_PATHWAY Signaling events mediated by HDAC Class III
0.0 1.0 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.0 0.8 ST_WNT_BETA_CATENIN_PATHWAY Wnt/beta-catenin Pathway
0.0 0.7 PID_ERB_GENOMIC_PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.6 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.0 0.4 PID_EPHA_FWDPATHWAY EPHA forward signaling
0.0 0.3 ST_JAK_STAT_PATHWAY Jak-STAT Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 14 of 14 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.8 REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 1.5 REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 1.5 REACTOME_INHIBITION_OF_VOLTAGE_GATED_CA2_CHANNELS_VIA_GBETA_GAMMA_SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 1.1 REACTOME_GLYCOSPHINGOLIPID_METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 1.0 REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 1.0 REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.7 REACTOME_DOPAMINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.0 0.6 REACTOME_MRNA_DECAY_BY_5_TO_3_EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.6 REACTOME_METAL_ION_SLC_TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.5 REACTOME_CDC6_ASSOCIATION_WITH_THE_ORC_ORIGIN_COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 0.5 REACTOME_ACYL_CHAIN_REMODELLING_OF_PG Genes involved in Acyl chain remodelling of PG
0.0 0.5 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_GOLGI_MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.5 REACTOME_A_TETRASACCHARIDE_LINKER_SEQUENCE_IS_REQUIRED_FOR_GAG_SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 0.3 REACTOME_GLUCAGON_TYPE_LIGAND_RECEPTORS Genes involved in Glucagon-type ligand receptors