Motif ID: GCAGCAU

Z-value: 0.440


Mature miRNA associated with seed GCAGCAU:

NamemiRBase Accession
hsa-miR-103a-3p MIMAT0000101
hsa-miR-107 MIMAT0000104



Activity profile for motif GCAGCAU.

activity profile for motif GCAGCAU


Sorted Z-values histogram for motif GCAGCAU

Sorted Z-values for motif GCAGCAU



Network of associatons between targets according to the STRING database.



First level regulatory network of GCAGCAU

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_+_151561085 1.019 ENST00000402676.2
 AKAP12
A kinase (PRKA) anchor protein 12
chr10_+_88718397 0.979 ENST00000372017.3
 SNCG
synuclein, gamma (breast cancer-specific protein 1)
chr15_+_69706585 0.869 ENST00000559279.1
ENST00000395392.2
 KIF23

kinesin family member 23

chr4_-_111119804 0.811 ENST00000394607.3
ENST00000302274.3
 ELOVL6

ELOVL fatty acid elongase 6

chr15_-_41624685 0.718 ENST00000560640.1
ENST00000220514.3
 OIP5

Opa interacting protein 5

chr10_-_106098162 0.616 ENST00000337478.1
 ITPRIP
inositol 1,4,5-trisphosphate receptor interacting protein
chr11_-_119599794 0.586 ENST00000264025.3
 PVRL1
poliovirus receptor-related 1 (herpesvirus entry mediator C)
chr3_-_98620500 0.584 ENST00000326840.6
 DCBLD2
discoidin, CUB and LCCL domain containing 2
chr12_+_66217911 0.547 ENST00000403681.2
 HMGA2
high mobility group AT-hook 2
chr4_-_99579733 0.533 ENST00000305798.3
 TSPAN5
tetraspanin 5
chr2_-_208030647 0.529 ENST00000309446.6
 KLF7
Kruppel-like factor 7 (ubiquitous)
chr1_-_20812690 0.492 ENST00000375078.3
 CAMK2N1
calcium/calmodulin-dependent protein kinase II inhibitor 1
chr21_-_16437255 0.479 ENST00000400199.1
ENST00000400202.1
 NRIP1

nuclear receptor interacting protein 1

chr22_-_36784035 0.478 ENST00000216181.5
 MYH9
myosin, heavy chain 9, non-muscle
chr1_+_109792641 0.461 ENST00000271332.3
 CELSR2
cadherin, EGF LAG seven-pass G-type receptor 2
chr12_-_8088871 0.446 ENST00000075120.7
 SLC2A3
solute carrier family 2 (facilitated glucose transporter), member 3
chr3_-_48130707 0.446 ENST00000360240.6
ENST00000383737.4
 MAP4

microtubule-associated protein 4

chr10_-_100995540 0.443 ENST00000370546.1
ENST00000404542.1
 HPSE2

heparanase 2

chr9_+_112810878 0.429 ENST00000434623.2
ENST00000374525.1
 AKAP2

A kinase (PRKA) anchor protein 2

chr20_-_5591626 0.426 ENST00000379019.4
 GPCPD1
glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 87 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.1 GO:0014046 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.1 1.0 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.2 0.9 GO:0044837 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.2 0.8 GO:0090402 oncogene-induced cell senescence(GO:0090402)
0.1 0.8 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.7 GO:0034080 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.1 0.5 GO:1903923 protein processing in phagocytic vesicle(GO:1900756) regulation of protein processing in phagocytic vesicle(GO:1903921) positive regulation of protein processing in phagocytic vesicle(GO:1903923)
0.1 0.5 GO:0090625 mRNA cleavage involved in gene silencing by siRNA(GO:0090625)
0.0 0.5 GO:0021999 neural plate anterior/posterior regionalization(GO:0021999)
0.0 0.5 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.1 0.4 GO:0018008 N-terminal peptidyl-glycine N-myristoylation(GO:0018008)
0.1 0.4 GO:0006597 spermine biosynthetic process(GO:0006597)
0.1 0.4 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.1 0.4 GO:0051012 microtubule sliding(GO:0051012)
0.0 0.4 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0 0.4 GO:0014051 gamma-aminobutyric acid secretion(GO:0014051)
0.1 0.3 GO:1904956 regulation of endodermal cell fate specification(GO:0042663) regulation of midbrain dopaminergic neuron differentiation(GO:1904956)
0.1 0.3 GO:0021718 superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722)
0.1 0.3 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.1 0.3 GO:1900425 negative regulation of defense response to bacterium(GO:1900425)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 21 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 0.9 GO:0097149 centralspindlin complex(GO:0097149)
0.1 0.8 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.0 0.7 GO:0010369 chromocenter(GO:0010369)
0.1 0.5 GO:0005826 actomyosin contractile ring(GO:0005826) myosin II filament(GO:0097513)
0.0 0.5 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.0 0.5 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.4 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.1 0.3 GO:0097134 cyclin E1-CDK2 complex(GO:0097134)
0.1 0.3 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0 0.3 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 0.3 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.2 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0 0.2 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.2 GO:0031414 N-terminal protein acetyltransferase complex(GO:0031414)
0.0 0.2 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.1 GO:1990425 ryanodine receptor complex(GO:1990425)
0.0 0.1 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.1 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 0.1 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.1 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 47 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.0 GO:0008179 adenylate cyclase binding(GO:0008179)
0.1 0.8 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.7 GO:0043495 protein anchor(GO:0043495)
0.0 0.6 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.2 0.5 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.1 0.5 GO:0035501 MH1 domain binding(GO:0035501)
0.1 0.4 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.1 0.4 GO:0098808 mRNA cap binding(GO:0098808)
0.1 0.4 GO:0019107 glycylpeptide N-tetradecanoyltransferase activity(GO:0004379) myristoyltransferase activity(GO:0019107)
0.1 0.4 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.1 0.4 GO:0030305 heparanase activity(GO:0030305)
0.0 0.4 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.1 0.3 GO:0004766 spermidine synthase activity(GO:0004766)
0.1 0.3 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.1 0.3 GO:0016534 cyclin-dependent protein kinase 5 activator activity(GO:0016534)
0.1 0.3 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.3 GO:0039706 co-receptor binding(GO:0039706)
0.0 0.3 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 0.3 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723)
0.0 0.3 GO:0003680 AT DNA binding(GO:0003680)

Gene overrepresentation in C2:CP category:

Showing 1 to 4 of 4 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.0 PID_AURORA_B_PATHWAY Aurora B signaling
0.0 0.4 PID_NCADHERIN_PATHWAY N-cadherin signaling events
0.0 0.3 SA_REG_CASCADE_OF_CYCLIN_EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.2 PID_IL5_PATHWAY IL5-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 15 of 15 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.8 REACTOME_SYNTHESIS_OF_VERY_LONG_CHAIN_FATTY_ACYL_COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.8 REACTOME_KINESINS Genes involved in Kinesins
0.0 0.7 REACTOME_METABOLISM_OF_POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.7 REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.6 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.5 REACTOME_SEMA4D_INDUCED_CELL_MIGRATION_AND_GROWTH_CONE_COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.4 REACTOME_MEMBRANE_BINDING_AND_TARGETTING_OF_GAG_PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.4 REACTOME_FACILITATIVE_NA_INDEPENDENT_GLUCOSE_TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.4 REACTOME_HS_GAG_DEGRADATION Genes involved in HS-GAG degradation
0.0 0.3 REACTOME_APOBEC3G_MEDIATED_RESISTANCE_TO_HIV1_INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.3 REACTOME_REGULATION_OF_AMPK_ACTIVITY_VIA_LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.0 0.3 REACTOME_ACTIVATED_POINT_MUTANTS_OF_FGFR2 Genes involved in Activated point mutants of FGFR2
0.0 0.3 REACTOME_PHOSPHORYLATION_OF_CD3_AND_TCR_ZETA_CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.2 REACTOME_GAMMA_CARBOXYLATION_TRANSPORT_AND_AMINO_TERMINAL_CLEAVAGE_OF_PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 0.2 REACTOME_ADENYLATE_CYCLASE_INHIBITORY_PATHWAY Genes involved in Adenylate cyclase inhibitory pathway