Motif ID: GGAAUGU

Z-value: 0.366


Mature miRNA associated with seed GGAAUGU:

NamemiRBase Accession
hsa-miR-1-3p MIMAT0000416
hsa-miR-206 MIMAT0000462
hsa-miR-613 MIMAT0003281



Activity profile for motif GGAAUGU.

activity profile for motif GGAAUGU


Sorted Z-values histogram for motif GGAAUGU

Sorted Z-values for motif GGAAUGU



Network of associatons between targets according to the STRING database.



First level regulatory network of GGAAUGU

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr5_-_172756506 0.603 ENST00000265087.4
STC2
stanniocalcin 2
chr12_+_4382917 0.584 ENST00000261254.3
CCND2
cyclin D2
chr17_-_53499310 0.379 ENST00000262065.3
MMD
monocyte to macrophage differentiation-associated
chr4_-_111119804 0.310 ENST00000394607.3
ENST00000302274.3
ELOVL6

ELOVL fatty acid elongase 6

chr14_+_20937538 0.306 ENST00000361505.5
ENST00000553591.1
PNP

purine nucleoside phosphorylase

chr3_-_123603137 0.227 ENST00000360304.3
ENST00000359169.1
ENST00000346322.5
ENST00000360772.3
MYLK



myosin light chain kinase



chr20_+_49126881 0.226 ENST00000371621.3
ENST00000541713.1
PTPN1

protein tyrosine phosphatase, non-receptor type 1

chr1_-_179198702 0.224 ENST00000502732.1
ABL2
c-abl oncogene 2, non-receptor tyrosine kinase
chr15_+_39873268 0.223 ENST00000397591.2
ENST00000260356.5
THBS1

thrombospondin 1

chr7_-_92463210 0.223 ENST00000265734.4
CDK6
cyclin-dependent kinase 6
chr9_+_131102925 0.207 ENST00000372870.1
ENST00000300456.4
SLC27A4

solute carrier family 27 (fatty acid transporter), member 4

chr10_-_33623564 0.204 ENST00000374875.1
ENST00000374822.4
NRP1

neuropilin 1

chr17_+_70117153 0.200 ENST00000245479.2
SOX9
SRY (sex determining region Y)-box 9
chr19_-_2151523 0.197 ENST00000350812.6
ENST00000355272.6
ENST00000356926.4
ENST00000345016.5
AP3D1



adaptor-related protein complex 3, delta 1 subunit



chr6_+_12290586 0.196 ENST00000379375.5
EDN1
endothelin 1
chr7_+_120628731 0.192 ENST00000310396.5
CPED1
cadherin-like and PC-esterase domain containing 1
chr8_-_49833978 0.191 ENST00000020945.1
SNAI2
snail family zinc finger 2
chr1_+_25943959 0.185 ENST00000374332.4
MAN1C1
mannosidase, alpha, class 1C, member 1
chr2_+_70142189 0.182 ENST00000264444.2
MXD1
MAX dimerization protein 1
chr17_-_41174424 0.173 ENST00000355653.3
VAT1
vesicle amine transport 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 62 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 0.6 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.0 0.6 GO:0071481 cellular response to X-ray(GO:0071481)
0.0 0.4 GO:1904627 response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.1 0.3 GO:0046495 nicotinamide riboside catabolic process(GO:0006738) nicotinamide riboside metabolic process(GO:0046495) pyridine nucleoside metabolic process(GO:0070637) pyridine nucleoside catabolic process(GO:0070638)
0.0 0.3 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 0.2 GO:2000646 positive regulation of receptor catabolic process(GO:2000646)
0.1 0.2 GO:0002605 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581) negative regulation of dendritic cell antigen processing and presentation(GO:0002605)
0.1 0.2 GO:0060516 primary prostatic bud elongation(GO:0060516) renal vesicle induction(GO:0072034)
0.1 0.2 GO:0036466 synaptic vesicle recycling via endosome(GO:0036466)
0.1 0.2 GO:0060585 regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.1 0.2 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.1 0.2 GO:1903966 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.0 0.2 GO:0010637 negative regulation of mitochondrial fusion(GO:0010637)
0.0 0.2 GO:1902378 vestibulocochlear nerve structural organization(GO:0021649) positive regulation of cytokine activity(GO:0060301) ganglion morphogenesis(GO:0061552) VEGF-activated neuropilin signaling pathway involved in axon guidance(GO:1902378) dorsal root ganglion morphogenesis(GO:1904835) otic placode development(GO:1905040)
0.0 0.2 GO:0061032 visceral serous pericardium development(GO:0061032)
0.0 0.2 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.0 0.2 GO:0042760 very long-chain fatty acid catabolic process(GO:0042760)
0.0 0.2 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.0 0.2 GO:0030578 PML body organization(GO:0030578)
0.0 0.2 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)

Gene overrepresentation in cellular_component category:

Showing 1 to 14 of 14 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 0.7 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.0 0.4 GO:0097443 sorting endosome(GO:0097443)
0.0 0.2 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.0 0.2 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.2 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.0 0.2 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 0.2 GO:0016600 flotillin complex(GO:0016600)
0.0 0.1 GO:0001674 female germ cell nucleus(GO:0001674)
0.0 0.1 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.1 GO:0005846 nuclear cap binding complex(GO:0005846)
0.0 0.1 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.0 0.1 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0 0.1 GO:0042643 actomyosin, actin portion(GO:0042643)
0.0 0.1 GO:0070545 PeBoW complex(GO:0070545)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 34 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 0.3 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.0 0.3 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 0.2 GO:0070052 collagen V binding(GO:0070052)
0.1 0.2 GO:0098770 FBXO family protein binding(GO:0098770)
0.0 0.2 GO:0031708 endothelin B receptor binding(GO:0031708)
0.0 0.2 GO:0016215 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.0 0.2 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.2 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.0 0.2 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.0 0.2 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.0 0.2 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.2 GO:0031957 fatty acid transporter activity(GO:0015245) very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.1 GO:0050659 N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity(GO:0050659)
0.0 0.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.1 GO:0051139 metal ion:proton antiporter activity(GO:0051139)
0.0 0.1 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0 0.1 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.0 0.1 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0 0.1 GO:0047057 oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
0.0 0.1 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)

Gene overrepresentation in C2:CP category:

Showing 1 to 3 of 3 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.8 PID_IL2_STAT5_PATHWAY IL2 signaling events mediated by STAT5
0.0 0.3 PID_VEGF_VEGFR_PATHWAY VEGF and VEGFR signaling network
0.0 0.3 SA_REG_CASCADE_OF_CYCLIN_EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 4 of 4 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.0 REACTOME_G1_PHASE Genes involved in G1 Phase
0.0 0.3 REACTOME_PURINE_CATABOLISM Genes involved in Purine catabolism
0.0 0.3 REACTOME_VEGF_LIGAND_RECEPTOR_INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.3 REACTOME_SYNTHESIS_OF_VERY_LONG_CHAIN_FATTY_ACYL_COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs