Motif ID: GLIS1

Z-value: 0.321


Transcription factors associated with GLIS1:

Gene SymbolEntrez IDGene Name
GLIS1 ENSG00000174332.3 GLIS1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
GLIS1hg19_v2_chr1_-_54199877_541998770.106.5e-01Click!


Activity profile for motif GLIS1.

activity profile for motif GLIS1


Sorted Z-values histogram for motif GLIS1

Sorted Z-values for motif GLIS1



Network of associatons between targets according to the STRING database.



First level regulatory network of GLIS1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr17_+_80332153 0.506 ENST00000313135.2
UTS2R
urotensin 2 receptor
chr4_+_191008560 0.412 ENST00000554690.1
DUX4L3
double homeobox 4 like 3
chr4_+_190992087 0.358 ENST00000553598.1
DUX4L7
double homeobox 4 like 7
chr4_+_190995380 0.351 ENST00000555191.1
DUX4L6
double homeobox 4 like 6
chr4_+_190998673 0.347 ENST00000554668.1
DUX4L5
double homeobox 4 like 5
chr4_+_191011860 0.340 ENST00000440426.1
DUX4L2
double homeobox 4 like 2
chr4_+_191005267 0.340 ENST00000556625.1
DUX4
double homeobox 4
chr4_+_191001979 0.336 ENST00000538692.1
DUX4L4
double homeobox 4 like 4
chr18_+_11751493 0.254 ENST00000269162.5
GNAL
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type
chr11_+_68671310 0.161 ENST00000255078.3
ENST00000539224.1
IGHMBP2

immunoglobulin mu binding protein 2

chr18_+_11752040 0.154 ENST00000423027.3
GNAL
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type
chr19_-_38397228 0.107 ENST00000447313.2
WDR87
WD repeat domain 87
chr19_+_40697514 0.103 ENST00000253055.3
MAP3K10
mitogen-activated protein kinase kinase kinase 10
chr11_-_68671264 0.083 ENST00000362034.2
MRPL21
mitochondrial ribosomal protein L21
chr19_-_42463418 0.079 ENST00000600292.1
ENST00000601078.1
ENST00000601891.1
ENST00000222008.6
RABAC1



Rab acceptor 1 (prenylated)



chr18_+_11751466 0.066 ENST00000535121.1
GNAL
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type
chr16_+_58059470 0.023 ENST00000219271.3
MMP15
matrix metallopeptidase 15 (membrane-inserted)
chr11_+_66886717 0.013 ENST00000398645.2
KDM2A
lysine (K)-specific demethylase 2A

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0046005 positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005)
0.0 0.3 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
0.0 0.5 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.0 0.1 GO:0007256 activation of JNKK activity(GO:0007256)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0032797 SMN complex(GO:0032797)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.2 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.0 0.5 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 PID_LPA4_PATHWAY LPA4-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 REACTOME_ADENYLATE_CYCLASE_ACTIVATING_PATHWAY Genes involved in Adenylate cyclase activating pathway