Motif ID: GMEB1

Z-value: 1.036


Transcription factors associated with GMEB1:

Gene SymbolEntrez IDGene Name
GMEB1 ENSG00000162419.8 GMEB1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
GMEB1hg19_v2_chr1_+_28995231_289952500.555.1e-03Click!


Activity profile for motif GMEB1.

activity profile for motif GMEB1


Sorted Z-values histogram for motif GMEB1

Sorted Z-values for motif GMEB1



Network of associatons between targets according to the STRING database.



First level regulatory network of GMEB1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr4_-_7044657 3.869 ENST00000310085.4
 CCDC96
coiled-coil domain containing 96
chr3_-_197676740 3.420 ENST00000452735.1
ENST00000453254.1
ENST00000455191.1
 IQCG


IQ motif containing G


chr17_-_4689649 2.975 ENST00000441199.2
ENST00000416307.2
 VMO1

vitelline membrane outer layer 1 homolog (chicken)

chr3_-_107941209 2.819 ENST00000492106.1
 IFT57
intraflagellar transport 57 homolog (Chlamydomonas)
chr10_+_22634384 2.781 ENST00000376624.3
ENST00000376603.2
ENST00000376601.1
ENST00000538630.1
ENST00000456231.2
ENST00000313311.6
ENST00000435326.1
 SPAG6






sperm associated antigen 6






chr10_+_23216944 2.747 ENST00000298032.5
ENST00000409983.3
ENST00000409049.3
 ARMC3


armadillo repeat containing 3


chr2_-_27712583 2.725 ENST00000260570.3
ENST00000359466.6
ENST00000416524.2
 IFT172


intraflagellar transport 172 homolog (Chlamydomonas)


chr10_+_23217006 2.725 ENST00000376528.4
ENST00000447081.1
 ARMC3

armadillo repeat containing 3

chr1_+_111888890 2.578 ENST00000369738.4
 PIFO
primary cilia formation
chr1_-_161337662 2.571 ENST00000367974.1
 C1orf192
chromosome 1 open reading frame 192
chr16_+_67840986 2.569 ENST00000561639.1
ENST00000567852.1
ENST00000565148.1
ENST00000388833.3
ENST00000561654.1
ENST00000431934.2
 TSNAXIP1





translin-associated factor X interacting protein 1





chrX_+_53449887 2.561 ENST00000375327.3
 RIBC1
RIB43A domain with coiled-coils 1
chr9_+_124922171 2.536 ENST00000373764.3
ENST00000536616.1
 MORN5

MORN repeat containing 5

chr16_-_75590114 2.461 ENST00000568377.1
ENST00000565067.1
ENST00000258173.6
 TMEM231


transmembrane protein 231


chr2_-_99771373 2.460 ENST00000393483.3
 TSGA10
testis specific, 10
chr1_-_36916066 2.305 ENST00000315643.9
 OSCP1
organic solute carrier partner 1
chr16_+_67840668 2.301 ENST00000415766.3
 TSNAXIP1
translin-associated factor X interacting protein 1
chr19_+_4639514 2.282 ENST00000327473.4
 TNFAIP8L1
tumor necrosis factor, alpha-induced protein 8-like 1
chr19_-_55677999 2.028 ENST00000532817.1
ENST00000527223.2
ENST00000391720.4
 DNAAF3


dynein, axonemal, assembly factor 3


chr2_-_160761179 2.013 ENST00000554112.1
ENST00000553424.1
ENST00000263636.4
ENST00000504764.1
ENST00000505052.1
 LY75


LY75-CD302

lymphocyte antigen 75


LY75-CD302 readthrough


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 349 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 7.5 GO:0060972 left/right pattern formation(GO:0060972)
0.0 5.9 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.1 4.0 GO:0071801 regulation of podosome assembly(GO:0071801)
0.3 3.4 GO:0007288 sperm axoneme assembly(GO:0007288)
0.0 3.2 GO:0060271 cilium morphogenesis(GO:0060271)
0.2 3.0 GO:0070314 G1 to G0 transition(GO:0070314)
0.7 2.7 GO:0035720 intraciliary anterograde transport(GO:0035720)
0.1 2.7 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.2 2.6 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.1 2.6 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 2.6 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 2.6 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.3 2.5 GO:1902412 regulation of mitotic cytokinesis(GO:1902412)
0.0 2.4 GO:0006521 regulation of cellular amino acid metabolic process(GO:0006521)
0.2 2.2 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.1 2.2 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 2.2 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.1 2.1 GO:0030322 stabilization of membrane potential(GO:0030322)
0.1 2.0 GO:0044458 motile cilium assembly(GO:0044458)
0.0 2.0 GO:0007602 phototransduction(GO:0007602)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 152 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 5.7 GO:0009925 basal plasma membrane(GO:0009925)
0.4 5.3 GO:0044292 dendrite terminus(GO:0044292)
0.7 4.9 GO:0002177 manchette(GO:0002177)
0.1 4.4 GO:0002102 podosome(GO:0002102)
0.0 4.0 GO:0031514 motile cilium(GO:0031514)
0.4 3.8 GO:0030991 intraciliary transport particle A(GO:0030991)
0.1 2.8 GO:0097542 ciliary tip(GO:0097542)
0.9 2.7 GO:0097598 sperm cytoplasmic droplet(GO:0097598)
0.1 2.7 GO:0036038 MKS complex(GO:0036038)
0.3 2.6 GO:0000235 astral microtubule(GO:0000235) aster(GO:0005818)
0.1 2.4 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.3 2.1 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.2 2.1 GO:1990111 spermatoproteasome complex(GO:1990111)
0.0 2.0 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 1.9 GO:0016605 PML body(GO:0016605)
0.2 1.8 GO:0042612 MHC class I protein complex(GO:0042612)
0.1 1.8 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.1 1.7 GO:0034709 methylosome(GO:0034709)
0.5 1.4 GO:0031933 telomeric heterochromatin(GO:0031933)
0.0 1.4 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 206 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 4.0 GO:0035064 methylated histone binding(GO:0035064)
0.0 3.9 GO:0003777 microtubule motor activity(GO:0003777)
1.0 2.9 GO:0052810 1-phosphatidylinositol-5-kinase activity(GO:0052810)
0.1 2.4 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 2.4 GO:0030544 Hsp70 protein binding(GO:0030544)
0.1 2.3 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.1 2.2 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1 2.1 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.2 1.7 GO:0044020 histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.5 1.6 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.2 1.6 GO:0046979 TAP2 binding(GO:0046979)
0.0 1.6 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.1 1.5 GO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282)
0.1 1.5 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 1.5 GO:0005262 calcium channel activity(GO:0005262)
0.0 1.4 GO:0001786 phosphatidylserine binding(GO:0001786)
0.1 1.3 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.4 1.2 GO:0033867 Fas-activated serine/threonine kinase activity(GO:0033867)
0.3 1.2 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.3 1.2 GO:0031849 olfactory receptor binding(GO:0031849)

Gene overrepresentation in C2:CP category:

Showing 1 to 20 of 31 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.9 PID_HEDGEHOG_GLI_PATHWAY Hedgehog signaling events mediated by Gli proteins
0.1 2.5 PID_WNT_CANONICAL_PATHWAY Canonical Wnt signaling pathway
0.0 2.4 PID_ECADHERIN_STABILIZATION_PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 1.5 PID_HES_HEY_PATHWAY Notch-mediated HES/HEY network
0.0 1.4 PID_BARD1_PATHWAY BARD1 signaling events
0.1 1.2 PID_THROMBIN_PAR4_PATHWAY PAR4-mediated thrombin signaling events
0.0 1.0 PID_IL5_PATHWAY IL5-mediated signaling events
0.0 0.8 PID_ERA_GENOMIC_PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.7 PID_IL12_STAT4_PATHWAY IL12 signaling mediated by STAT4
0.0 0.7 PID_HDAC_CLASSI_PATHWAY Signaling events mediated by HDAC Class I
0.0 0.6 PID_SMAD2_3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.6 PID_IL2_PI3K_PATHWAY IL2 signaling events mediated by PI3K
0.0 0.6 PID_PS1_PATHWAY Presenilin action in Notch and Wnt signaling
0.0 0.6 ST_WNT_BETA_CATENIN_PATHWAY Wnt/beta-catenin Pathway
0.0 0.6 PID_ARF6_PATHWAY Arf6 signaling events
0.1 0.5 PID_BETA_CATENIN_DEG_PATHWAY Degradation of beta catenin
0.0 0.5 PID_DNA_PK_PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.5 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.4 PID_FRA_PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.4 PID_NFKAPPAB_CANONICAL_PATHWAY Canonical NF-kappaB pathway

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 20 of 51 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 5.6 REACTOME_GENERIC_TRANSCRIPTION_PATHWAY Genes involved in Generic Transcription Pathway
0.1 4.5 REACTOME_KINESINS Genes involved in Kinesins
0.0 2.4 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_PLASMA_MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 2.1 REACTOME_CROSS_PRESENTATION_OF_SOLUBLE_EXOGENOUS_ANTIGENS_ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.2 1.8 REACTOME_ENDOSOMAL_VACUOLAR_PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.1 1.6 REACTOME_TRANSLOCATION_OF_ZAP_70_TO_IMMUNOLOGICAL_SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 1.6 REACTOME_NEP_NS2_INTERACTS_WITH_THE_CELLULAR_EXPORT_MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.1 1.3 REACTOME_PROLACTIN_RECEPTOR_SIGNALING Genes involved in Prolactin receptor signaling
0.1 1.2 REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 1.1 REACTOME_LATENT_INFECTION_OF_HOMO_SAPIENS_WITH_MYCOBACTERIUM_TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.1 1.0 REACTOME_PLATELET_ADHESION_TO_EXPOSED_COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.9 REACTOME_INTEGRATION_OF_PROVIRUS Genes involved in Integration of provirus
0.0 0.8 REACTOME_G2_M_DNA_DAMAGE_CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.1 0.7 REACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.7 REACTOME_CDC6_ASSOCIATION_WITH_THE_ORC_ORIGIN_COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 0.7 REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.6 REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.6 REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_PDH_COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.6 REACTOME_PROCESSIVE_SYNTHESIS_ON_THE_LAGGING_STRAND Genes involved in Processive synthesis on the lagging strand
0.0 0.6 REACTOME_SIGNALING_BY_NOTCH4 Genes involved in Signaling by NOTCH4