Motif ID: GMEB2

Z-value: 0.943


Transcription factors associated with GMEB2:

Gene SymbolEntrez IDGene Name
GMEB2 ENSG00000101216.6 GMEB2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
GMEB2hg19_v2_chr20_-_62258394_622584640.038.7e-01Click!


Activity profile for motif GMEB2.

activity profile for motif GMEB2


Sorted Z-values histogram for motif GMEB2

Sorted Z-values for motif GMEB2



Network of associatons between targets according to the STRING database.



First level regulatory network of GMEB2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr15_+_66797627 0.916 ENST00000565627.1
ENST00000564179.1
ZWILCH

zwilch kinetochore protein

chr15_+_66797455 0.838 ENST00000446801.2
ZWILCH
zwilch kinetochore protein
chr1_+_92495528 0.830 ENST00000370383.4
EPHX4
epoxide hydrolase 4
chr7_+_120590803 0.776 ENST00000315870.5
ENST00000339121.5
ENST00000445699.1
ING3


inhibitor of growth family, member 3


chr4_-_74964904 0.766 ENST00000508487.2
CXCL2
chemokine (C-X-C motif) ligand 2
chr5_+_162887556 0.707 ENST00000393915.4
ENST00000432118.2
ENST00000358715.3
HMMR


hyaluronan-mediated motility receptor (RHAMM)


chr18_+_2571510 0.678 ENST00000261597.4
ENST00000575515.1
NDC80

NDC80 kinetochore complex component

chr12_+_122064673 0.676 ENST00000537188.1
ORAI1
ORAI calcium release-activated calcium modulator 1
chr5_-_74162605 0.648 ENST00000389156.4
ENST00000510496.1
ENST00000380515.3
FAM169A


family with sequence similarity 169, member A


chr7_+_100472717 0.646 ENST00000457580.2
ENST00000388793.4
ENST00000432932.1
ENST00000347433.4
SRRT



serrate RNA effector molecule homolog (Arabidopsis)



chr11_-_65667997 0.637 ENST00000312562.2
ENST00000534222.1
FOSL1

FOS-like antigen 1

chr16_-_46655538 0.618 ENST00000303383.3
SHCBP1
SHC SH2-domain binding protein 1
chr7_-_45026159 0.610 ENST00000584327.1
ENST00000438705.3
SNHG15

small nucleolar RNA host gene 15 (non-protein coding)

chr11_-_65667884 0.587 ENST00000448083.2
ENST00000531493.1
ENST00000532401.1
FOSL1


FOS-like antigen 1


chr5_+_149340282 0.585 ENST00000286298.4
SLC26A2
solute carrier family 26 (anion exchanger), member 2
chr11_+_61583721 0.569 ENST00000257261.6
FADS2
fatty acid desaturase 2
chr15_+_40453204 0.567 ENST00000287598.6
ENST00000412359.3
BUB1B

BUB1 mitotic checkpoint serine/threonine kinase B

chr7_-_45026419 0.556 ENST00000578968.1
ENST00000580528.1
SNHG15

small nucleolar RNA host gene 15 (non-protein coding)

chr2_+_183989083 0.554 ENST00000295119.4
NUP35
nucleoporin 35kDa
chr2_+_183989157 0.552 ENST00000541912.1
NUP35
nucleoporin 35kDa
chr8_+_48873479 0.545 ENST00000262105.2
MCM4
minichromosome maintenance complex component 4
chr3_-_170588163 0.526 ENST00000295830.8
RPL22L1
ribosomal protein L22-like 1
chr4_-_148605265 0.523 ENST00000541232.1
ENST00000322396.6
PRMT10

protein arginine methyltransferase 10 (putative)

chr5_-_137368708 0.523 ENST00000033079.3
FAM13B
family with sequence similarity 13, member B
chr8_+_48873453 0.518 ENST00000523944.1
MCM4
minichromosome maintenance complex component 4
chr11_+_60609537 0.505 ENST00000227520.5
CCDC86
coiled-coil domain containing 86
chr7_-_45151272 0.485 ENST00000461363.1
ENST00000495078.1
ENST00000494076.1
ENST00000478532.1
ENST00000258770.3
ENST00000361278.3
TBRG4





transforming growth factor beta regulator 4





chr10_+_13203543 0.483 ENST00000378714.3
ENST00000479669.1
ENST00000484800.2
MCM10


minichromosome maintenance complex component 10


chr12_+_50355647 0.482 ENST00000293599.6
AQP5
aquaporin 5
chr19_-_663277 0.482 ENST00000292363.5
RNF126
ring finger protein 126
chr6_-_136571400 0.480 ENST00000418509.2
ENST00000420702.1
ENST00000451457.2
MTFR2


mitochondrial fission regulator 2


chr5_-_159739532 0.479 ENST00000520748.1
ENST00000393977.3
ENST00000257536.7
CCNJL


cyclin J-like


chr8_-_124408652 0.471 ENST00000287394.5
ATAD2
ATPase family, AAA domain containing 2
chr7_-_19748640 0.464 ENST00000222567.5
TWISTNB
TWIST neighbor
chr19_+_18303992 0.461 ENST00000599612.2
MPV17L2
MPV17 mitochondrial membrane protein-like 2
chr9_+_91933726 0.452 ENST00000534113.2
SECISBP2
SECIS binding protein 2
chr3_+_111718173 0.450 ENST00000494932.1
TAGLN3
transgelin 3
chrX_+_105855160 0.448 ENST00000372544.2
ENST00000372548.4
CXorf57

chromosome X open reading frame 57

chr16_-_3493528 0.448 ENST00000301744.4
ZNF597
zinc finger protein 597
chr13_+_48611665 0.444 ENST00000258662.2
NUDT15
nudix (nucleoside diphosphate linked moiety X)-type motif 15
chr15_-_23034322 0.442 ENST00000539711.2
ENST00000560039.1
ENST00000398013.3
ENST00000337451.3
ENST00000359727.4
ENST00000398014.2
NIPA2





non imprinted in Prader-Willi/Angelman syndrome 2





chr3_-_170587974 0.439 ENST00000463836.1
RPL22L1
ribosomal protein L22-like 1
chr6_-_31763408 0.436 ENST00000444930.2
VARS
valyl-tRNA synthetase
chr17_+_56769924 0.435 ENST00000461271.1
ENST00000583539.1
ENST00000337432.4
ENST00000421782.2
RAD51C



RAD51 paralog C



chr3_+_124449213 0.434 ENST00000232607.2
ENST00000536109.1
ENST00000538242.1
ENST00000413078.2
UMPS



uridine monophosphate synthetase



chr1_+_91966384 0.433 ENST00000430031.2
ENST00000234626.6
CDC7

cell division cycle 7

chr3_-_195808980 0.431 ENST00000360110.4
TFRC
transferrin receptor
chr10_+_60145155 0.422 ENST00000373895.3
TFAM
transcription factor A, mitochondrial
chr2_+_109403193 0.422 ENST00000412964.2
ENST00000295124.4
CCDC138

coiled-coil domain containing 138

chr9_-_139137648 0.420 ENST00000358701.5
QSOX2
quiescin Q6 sulfhydryl oxidase 2
chr2_+_216176761 0.420 ENST00000540518.1
ENST00000435675.1
ATIC

5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase

chr22_-_41940404 0.414 ENST00000355209.4
ENST00000337566.5
ENST00000396504.2
ENST00000407461.1
POLR3H



polymerase (RNA) III (DNA directed) polypeptide H (22.9kD)



chr10_+_103912137 0.413 ENST00000603742.1
ENST00000488254.2
ENST00000461421.1
ENST00000476468.1
ENST00000370007.5
NOLC1




nucleolar and coiled-body phosphoprotein 1




chr1_-_53793584 0.412 ENST00000354412.3
ENST00000347547.2
ENST00000306052.6
LRP8


low density lipoprotein receptor-related protein 8, apolipoprotein e receptor


chr2_+_178077477 0.408 ENST00000411529.2
ENST00000435711.1
HNRNPA3

heterogeneous nuclear ribonucleoprotein A3

chr19_+_4402659 0.406 ENST00000301280.5
ENST00000585854.1
CHAF1A

chromatin assembly factor 1, subunit A (p150)

chr4_+_113152978 0.403 ENST00000309703.6
AP1AR
adaptor-related protein complex 1 associated regulatory protein
chr4_+_75311019 0.402 ENST00000502307.1
AREG
amphiregulin
chr1_-_238649319 0.396 ENST00000400946.2
RP11-371I1.2
long intergenic non-protein coding RNA 1139
chr14_-_53258314 0.395 ENST00000216410.3
ENST00000557604.1
GNPNAT1

glucosamine-phosphate N-acetyltransferase 1

chr11_+_43333513 0.393 ENST00000534695.1
ENST00000455725.2
ENST00000531273.1
ENST00000420461.2
ENST00000378852.3
ENST00000534600.1
API5





apoptosis inhibitor 5





chr3_+_58223228 0.391 ENST00000478253.1
ENST00000295962.4
ABHD6

abhydrolase domain containing 6

chr1_+_91966656 0.384 ENST00000428239.1
ENST00000426137.1
CDC7

cell division cycle 7

chr3_+_99536663 0.381 ENST00000421999.2
ENST00000463526.1
CMSS1

cms1 ribosomal small subunit homolog (yeast)

chr4_+_75310851 0.381 ENST00000395748.3
ENST00000264487.2
AREG

amphiregulin

chr22_-_42017021 0.379 ENST00000263256.6
DESI1
desumoylating isopeptidase 1
chr10_+_103911926 0.367 ENST00000605788.1
ENST00000405356.1
NOLC1

nucleolar and coiled-body phosphoprotein 1

chr13_-_108867846 0.365 ENST00000442234.1
LIG4
ligase IV, DNA, ATP-dependent
chr12_-_50419177 0.364 ENST00000454520.2
ENST00000546595.1
ENST00000548824.1
ENST00000549777.1
ENST00000546723.1
ENST00000427314.2
ENST00000552157.1
ENST00000552310.1
ENST00000548644.1
ENST00000312377.5
ENST00000546786.1
ENST00000550149.1
ENST00000546764.1
ENST00000552004.1
ENST00000548320.1
ENST00000547905.1
ENST00000550651.1
ENST00000551145.1
ENST00000434422.1
ENST00000552921.1
RACGAP1



















Rac GTPase activating protein 1



















chr4_-_83295103 0.362 ENST00000313899.7
ENST00000352301.4
ENST00000509107.1
ENST00000353341.4
ENST00000541060.1
HNRNPD




heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)




chr17_+_46970178 0.359 ENST00000393366.2
ENST00000506855.1
ATP5G1

ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)

chr14_+_73525265 0.358 ENST00000525161.1
RBM25
RNA binding motif protein 25
chr17_+_7462103 0.356 ENST00000396545.4
TNFSF13
tumor necrosis factor (ligand) superfamily, member 13
chr5_-_68665296 0.353 ENST00000512152.1
ENST00000503245.1
ENST00000512561.1
ENST00000380822.4
TAF9



TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa



chr21_-_34914394 0.353 ENST00000361093.5
ENST00000381815.4
GART

phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase

chr19_+_56989609 0.353 ENST00000601875.1
ZNF667-AS1
ZNF667 antisense RNA 1 (head to head)
chr1_-_200589859 0.352 ENST00000367350.4
KIF14
kinesin family member 14
chr1_+_104198377 0.351 ENST00000370083.4
AMY1A
amylase, alpha 1A (salivary)
chr12_+_104359641 0.347 ENST00000537100.1
TDG
thymine-DNA glycosylase
chr4_-_159593179 0.346 ENST00000379205.4
C4orf46
chromosome 4 open reading frame 46
chr14_+_73525144 0.340 ENST00000261973.7
ENST00000540173.1
RBM25

RNA binding motif protein 25

chr17_+_7462031 0.338 ENST00000380535.4
TNFSF13
tumor necrosis factor (ligand) superfamily, member 13
chr10_-_97416400 0.338 ENST00000371224.2
ENST00000371221.3
ALDH18A1

aldehyde dehydrogenase 18 family, member A1

chrX_+_153991025 0.337 ENST00000369550.5
DKC1
dyskeratosis congenita 1, dyskerin
chr7_-_97501706 0.337 ENST00000455086.1
ENST00000453600.1
ASNS

asparagine synthetase (glutamine-hydrolyzing)

chr16_-_279405 0.337 ENST00000430864.1
ENST00000293872.8
ENST00000337351.4
ENST00000397783.1
LUC7L



LUC7-like (S. cerevisiae)



chr17_-_61905005 0.335 ENST00000584574.1
ENST00000585145.1
ENST00000427159.2
FTSJ3


FtsJ homolog 3 (E. coli)


chr1_-_31769595 0.335 ENST00000263694.4
SNRNP40
small nuclear ribonucleoprotein 40kDa (U5)
chr16_-_4588822 0.330 ENST00000564828.1
CDIP1
cell death-inducing p53 target 1
chr17_+_46970127 0.328 ENST00000355938.5
ATP5G1
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)
chr20_-_5107180 0.327 ENST00000379160.3
PCNA
proliferating cell nuclear antigen
chr4_-_159592996 0.326 ENST00000508457.1
C4orf46
chromosome 4 open reading frame 46
chrX_-_64754611 0.322 ENST00000374807.5
ENST00000374811.3
ENST00000374804.5
ENST00000312391.8
LAS1L



LAS1-like (S. cerevisiae)



chr9_+_106856831 0.322 ENST00000303219.8
ENST00000374787.3
SMC2

structural maintenance of chromosomes 2

chr16_-_4588762 0.320 ENST00000562334.1
ENST00000562579.1
ENST00000567695.1
ENST00000563507.1
CDIP1



cell death-inducing p53 target 1



chr5_-_76383133 0.320 ENST00000255198.2
ZBED3
zinc finger, BED-type containing 3
chr17_+_7461781 0.320 ENST00000349228.4
TNFSF13
tumor necrosis factor (ligand) superfamily, member 13
chr17_-_62097904 0.319 ENST00000583366.1
ICAM2
intercellular adhesion molecule 2
chr19_-_49250054 0.315 ENST00000602105.1
ENST00000332955.2
IZUMO1

izumo sperm-egg fusion 1

chr6_-_3157760 0.314 ENST00000333628.3
TUBB2A
tubulin, beta 2A class IIa
chr3_+_180319918 0.313 ENST00000296015.4
ENST00000491380.1
ENST00000412756.2
ENST00000382584.4
TTC14



tetratricopeptide repeat domain 14



chr12_+_120884222 0.312 ENST00000551765.1
ENST00000229384.5
GATC

glutamyl-tRNA(Gln) amidotransferase, subunit C

chr1_-_100598444 0.310 ENST00000535161.1
ENST00000287482.5
SASS6

spindle assembly 6 homolog (C. elegans)

chr17_+_7461849 0.307 ENST00000338784.4
TNFSF13
tumor necrosis factor (ligand) superfamily, member 13
chr1_-_31769656 0.306 ENST00000446633.2
SNRNP40
small nuclear ribonucleoprotein 40kDa (U5)
chr10_+_60144782 0.303 ENST00000487519.1
TFAM
transcription factor A, mitochondrial
chr3_-_47823298 0.303 ENST00000254480.5
SMARCC1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1
chr10_+_35416090 0.302 ENST00000354759.3
CREM
cAMP responsive element modulator
chr10_+_35415851 0.302 ENST00000374726.3
CREM
cAMP responsive element modulator
chr12_-_89919965 0.297 ENST00000548729.1
POC1B-GALNT4
POC1B-GALNT4 readthrough
chr3_-_14166316 0.295 ENST00000396914.3
ENST00000295767.5
CHCHD4

coiled-coil-helix-coiled-coil-helix domain containing 4

chr2_-_153573965 0.295 ENST00000448428.1
PRPF40A
PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae)
chr9_+_91933407 0.295 ENST00000375807.3
ENST00000339901.4
SECISBP2

SECIS binding protein 2

chr10_+_35416223 0.295 ENST00000489321.1
ENST00000427847.2
ENST00000345491.3
ENST00000395895.2
ENST00000374728.3
ENST00000487132.1
CREM





cAMP responsive element modulator





chr5_-_68665469 0.292 ENST00000217893.5
TAF9
TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa
chr11_+_112097069 0.292 ENST00000280362.3
ENST00000525803.1
PTS

6-pyruvoyltetrahydropterin synthase

chr2_+_27440229 0.292 ENST00000264705.4
ENST00000403525.1
CAD

carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase

chr20_+_361890 0.292 ENST00000449710.1
ENST00000422053.2
TRIB3

tribbles pseudokinase 3

chr9_+_133569108 0.292 ENST00000372358.5
ENST00000546165.1
ENST00000372352.3
ENST00000372351.3
ENST00000372350.3
ENST00000495699.2
EXOSC2





exosome component 2





chr10_-_70287172 0.291 ENST00000539557.1
SLC25A16
solute carrier family 25 (mitochondrial carrier; Graves disease autoantigen), member 16
chr8_-_10697370 0.289 ENST00000314787.3
ENST00000426190.2
ENST00000519088.1
PINX1


PIN2/TERF1 interacting, telomerase inhibitor 1


chr17_-_61850894 0.289 ENST00000403162.3
ENST00000582252.1
ENST00000225726.5
CCDC47


coiled-coil domain containing 47


chr13_-_31736478 0.286 ENST00000445273.2
HSPH1
heat shock 105kDa/110kDa protein 1
chr17_+_46970134 0.285 ENST00000503641.1
ENST00000514808.1
ATP5G1

ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)

chr3_-_186288097 0.285 ENST00000446782.1
TBCCD1
TBCC domain containing 1
chr2_-_38978492 0.283 ENST00000409276.1
ENST00000446327.2
ENST00000313117.6
SRSF7


serine/arginine-rich splicing factor 7


chr10_+_35415719 0.281 ENST00000474362.1
ENST00000374721.3
CREM

cAMP responsive element modulator

chr6_+_126661253 0.279 ENST00000368326.1
ENST00000368325.1
ENST00000368328.4
CENPW


centromere protein W


chr19_-_55690758 0.278 ENST00000590851.1
SYT5
synaptotagmin V
chr20_+_37377085 0.275 ENST00000243903.4
ACTR5
ARP5 actin-related protein 5 homolog (yeast)
chr2_+_109335929 0.274 ENST00000283195.6
RANBP2
RAN binding protein 2
chr2_-_120124258 0.273 ENST00000409877.1
ENST00000409523.1
ENST00000409466.2
ENST00000414534.1
C2orf76



chromosome 2 open reading frame 76



chr18_+_71815743 0.273 ENST00000169551.6
ENST00000580087.1
TIMM21

translocase of inner mitochondrial membrane 21 homolog (yeast)

chr15_-_35280426 0.272 ENST00000559564.1
ENST00000356321.4
ZNF770

zinc finger protein 770

chr7_-_73668692 0.270 ENST00000352131.3
ENST00000055077.3
RFC2

replication factor C (activator 1) 2, 40kDa

chr12_+_104359576 0.270 ENST00000392872.3
ENST00000436021.2
TDG

thymine-DNA glycosylase

chr8_-_80942467 0.268 ENST00000518271.1
ENST00000276585.4
ENST00000521605.1
MRPS28


mitochondrial ribosomal protein S28


chr4_+_113152881 0.267 ENST00000274000.5
AP1AR
adaptor-related protein complex 1 associated regulatory protein
chr15_-_66084428 0.266 ENST00000443035.3
ENST00000431932.2
DENND4A

DENN/MADD domain containing 4A

chr16_+_19079215 0.261 ENST00000544894.2
ENST00000561858.1
COQ7

coenzyme Q7 homolog, ubiquinone (yeast)

chr10_-_27529486 0.260 ENST00000375888.1
ACBD5
acyl-CoA binding domain containing 5
chr7_-_154863264 0.258 ENST00000395731.2
ENST00000543018.1
HTR5A-AS1

HTR5A antisense RNA 1

chr17_-_76836963 0.256 ENST00000312010.6
USP36
ubiquitin specific peptidase 36
chr11_-_66112555 0.255 ENST00000425825.2
ENST00000359957.3
BRMS1

breast cancer metastasis suppressor 1

chr4_+_113066552 0.254 ENST00000309733.5
C4orf32
chromosome 4 open reading frame 32
chr1_-_161087802 0.253 ENST00000368010.3
PFDN2
prefoldin subunit 2
chr10_-_113943447 0.253 ENST00000369425.1
ENST00000348367.4
ENST00000423155.1
GPAM


glycerol-3-phosphate acyltransferase, mitochondrial


chr8_+_22224811 0.251 ENST00000381237.1
SLC39A14
solute carrier family 39 (zinc transporter), member 14
chr1_-_229644034 0.251 ENST00000366678.3
ENST00000261396.3
ENST00000537506.1
NUP133


nucleoporin 133kDa


chr3_+_111718036 0.248 ENST00000455401.2
TAGLN3
transgelin 3
chr19_+_50979753 0.247 ENST00000597426.1
ENST00000334976.6
ENST00000376918.3
ENST00000598585.1
EMC10



ER membrane protein complex subunit 10



chr7_-_156685841 0.247 ENST00000354505.4
ENST00000540390.1
LMBR1

limb development membrane protein 1

chr15_+_78833071 0.245 ENST00000559365.1
PSMA4
proteasome (prosome, macropain) subunit, alpha type, 4
chr16_+_19079311 0.244 ENST00000569127.1
COQ7
coenzyme Q7 homolog, ubiquinone (yeast)
chr1_+_205682497 0.243 ENST00000598338.1
AC119673.1
AC119673.1
chr8_-_80942139 0.242 ENST00000521434.1
ENST00000519120.1
ENST00000520946.1
MRPS28


mitochondrial ribosomal protein S28


chr14_+_50065459 0.242 ENST00000318317.4
LRR1
leucine rich repeat protein 1
chr5_+_121297650 0.240 ENST00000339397.4
SRFBP1
serum response factor binding protein 1
chrX_+_11129388 0.239 ENST00000321143.4
ENST00000380763.3
ENST00000380762.4
HCCS


holocytochrome c synthase


chr3_-_170587815 0.238 ENST00000466674.1
RPL22L1
ribosomal protein L22-like 1
chr12_+_102513950 0.237 ENST00000378128.3
ENST00000327680.2
ENST00000541394.1
ENST00000543784.1
PARPBP



PARP1 binding protein



chr15_-_52861157 0.237 ENST00000564163.1
ARPP19
cAMP-regulated phosphoprotein, 19kDa
chr2_-_198299726 0.237 ENST00000409915.4
ENST00000487698.1
ENST00000414963.2
ENST00000335508.6
SF3B1



splicing factor 3b, subunit 1, 155kDa



chr20_+_31407692 0.236 ENST00000375571.5
MAPRE1
microtubule-associated protein, RP/EB family, member 1
chr3_+_111578131 0.235 ENST00000498699.1
PHLDB2
pleckstrin homology-like domain, family B, member 2
chr14_+_53196872 0.232 ENST00000442123.2
ENST00000354586.4
STYX

serine/threonine/tyrosine interacting protein

chr22_-_42343117 0.232 ENST00000407253.3
ENST00000215980.5
CENPM

centromere protein M

chr17_+_38296576 0.231 ENST00000264645.7
CASC3
cancer susceptibility candidate 3
chr10_+_127408263 0.231 ENST00000337623.3
C10orf137
erythroid differentiation regulatory factor 1
chr17_-_15903002 0.230 ENST00000399277.1
ZSWIM7
zinc finger, SWIM-type containing 7
chr10_+_35415978 0.230 ENST00000429130.3
ENST00000469949.2
ENST00000460270.1
CREM


cAMP responsive element modulator


chr12_+_8234807 0.229 ENST00000339754.5
NECAP1
NECAP endocytosis associated 1
chr2_-_153573887 0.227 ENST00000493468.2
ENST00000545856.1
PRPF40A

PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae)

chr9_-_131084497 0.227 ENST00000546104.1
TRUB2
TruB pseudouridine (psi) synthase family member 2
chr20_+_54933971 0.226 ENST00000371384.3
ENST00000437418.1
FAM210B

family with sequence similarity 210, member B

chr3_-_160822858 0.226 ENST00000488170.1
B3GALNT1
beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
chrX_+_37545012 0.226 ENST00000378616.3
XK
X-linked Kx blood group (McLeod syndrome)
chr8_-_80942061 0.225 ENST00000519386.1
MRPS28
mitochondrial ribosomal protein S28
chr14_-_20923195 0.224 ENST00000206542.4
OSGEP
O-sialoglycoprotein endopeptidase
chr2_+_118572226 0.224 ENST00000263239.2
DDX18
DEAD (Asp-Glu-Ala-Asp) box polypeptide 18
chr4_-_111119804 0.222 ENST00000394607.3
ENST00000302274.3
ELOVL6

ELOVL fatty acid elongase 6

chr7_+_5632436 0.222 ENST00000340250.6
ENST00000382361.3
FSCN1

fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus)

chr2_+_75185619 0.221 ENST00000483063.1
POLE4
polymerase (DNA-directed), epsilon 4, accessory subunit
chr7_-_102985035 0.221 ENST00000426036.2
ENST00000249270.7
ENST00000454277.1
ENST00000412522.1
DNAJC2



DnaJ (Hsp40) homolog, subfamily C, member 2



chr11_-_134093827 0.221 ENST00000534548.2
NCAPD3
non-SMC condensin II complex, subunit D3
chr22_-_38349552 0.220 ENST00000422191.1
ENST00000249079.2
ENST00000418863.1
ENST00000403305.1
ENST00000403026.1
C22orf23




chromosome 22 open reading frame 23




chr3_+_184056614 0.220 ENST00000453072.1
FAM131A
family with sequence similarity 131, member A
chr19_-_55677999 0.219 ENST00000532817.1
ENST00000527223.2
ENST00000391720.4
DNAAF3


dynein, axonemal, assembly factor 3


chr17_+_66511540 0.218 ENST00000588188.2
PRKAR1A
protein kinase, cAMP-dependent, regulatory, type I, alpha
chr22_-_42342692 0.217 ENST00000404067.1
ENST00000402338.1
CENPM

centromere protein M

chrX_+_48755202 0.215 ENST00000447146.2
ENST00000376548.5
ENST00000247140.4
PQBP1


polyglutamine binding protein 1


chr6_+_25992884 0.212 ENST00000606723.2
U91328.19
U91328.19
chr6_+_26204825 0.212 ENST00000360441.4
HIST1H4E
histone cluster 1, H4e
chr3_-_196669298 0.211 ENST00000411704.1
ENST00000452404.2
NCBP2

nuclear cap binding protein subunit 2, 20kDa

chr10_+_1034338 0.211 ENST00000360803.4
ENST00000538293.1
GTPBP4

GTP binding protein 4

chr11_+_120039685 0.210 ENST00000530303.1
ENST00000319763.1
AP000679.2

Uncharacterized protein

chr18_+_5238549 0.210 ENST00000580684.1
LINC00667
long intergenic non-protein coding RNA 667
chr12_+_7079944 0.209 ENST00000261406.6
EMG1
EMG1 N1-specific pseudouridine methyltransferase
chr3_-_50374869 0.208 ENST00000327761.3
RASSF1
Ras association (RalGDS/AF-6) domain family member 1
chr12_+_122064398 0.206 ENST00000330079.7
ORAI1
ORAI calcium release-activated calcium modulator 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0044205 'de novo' UMP biosynthetic process(GO:0044205)
0.2 0.7 GO:0048203 vesicle targeting, trans-Golgi to endosome(GO:0048203)
0.2 1.3 GO:0007296 vitellogenesis(GO:0007296)
0.2 0.8 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.2 0.6 GO:1902544 regulation of DNA N-glycosylase activity(GO:1902544)
0.1 0.4 GO:0009107 lipoate biosynthetic process(GO:0009107)
0.1 0.5 GO:0048698 negative regulation of collateral sprouting in absence of injury(GO:0048698)
0.1 0.4 GO:0051102 DNA ligation involved in DNA recombination(GO:0051102)
0.1 1.5 GO:0048298 positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.1 1.1 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.1 0.4 GO:0046452 dihydrofolate metabolic process(GO:0046452)
0.1 0.3 GO:0070681 glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
0.1 0.8 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.1 0.9 GO:0045144 meiotic sister chromatid segregation(GO:0045144)
0.1 0.1 GO:1902299 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.1 0.4 GO:0006408 snRNA export from nucleus(GO:0006408) positive regulation of RNA export from nucleus(GO:0046833)
0.1 0.4 GO:0051083 'de novo' cotranslational protein folding(GO:0051083)
0.1 0.5 GO:0015670 carbon dioxide transport(GO:0015670)
0.1 0.3 GO:0006424 glutamyl-tRNA aminoacylation(GO:0006424) prolyl-tRNA aminoacylation(GO:0006433)
0.1 0.4 GO:0044837 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.1 0.4 GO:1901355 response to rapamycin(GO:1901355)
0.1 0.5 GO:0097680 double-strand break repair via classical nonhomologous end joining(GO:0097680)
0.1 0.5 GO:0071051 polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.1 0.4 GO:0006203 dGTP catabolic process(GO:0006203)
0.1 0.4 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
0.1 0.3 GO:0070981 L-asparagine biosynthetic process(GO:0070981) L-asparagine metabolic process(GO:0070982)
0.1 0.3 GO:0031126 snoRNA 3'-end processing(GO:0031126)
0.1 0.7 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.1 0.3 GO:1902990 leading strand elongation(GO:0006272) mitotic telomere maintenance via semi-conservative replication(GO:1902990)
0.1 0.2 GO:1903031 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.1 0.7 GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.1 1.0 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.1 0.5 GO:0061668 mitochondrial ribosome assembly(GO:0061668)
0.1 0.8 GO:0090267 positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267)
0.1 0.5 GO:0060744 thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744)
0.1 0.2 GO:0031133 regulation of axon diameter(GO:0031133)
0.1 0.2 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.1 0.6 GO:0050428 purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
0.1 0.8 GO:0007000 nucleolus organization(GO:0007000)
0.1 0.4 GO:0032487 regulation of Rap protein signal transduction(GO:0032487)
0.1 0.2 GO:0033341 regulation of collagen binding(GO:0033341)
0.1 0.3 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.1 0.4 GO:0006041 glucosamine metabolic process(GO:0006041)
0.1 0.2 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.1 0.4 GO:0030242 pexophagy(GO:0030242)
0.1 0.3 GO:0002086 diaphragm contraction(GO:0002086)
0.1 0.4 GO:0046098 guanine metabolic process(GO:0046098)
0.1 0.3 GO:0051664 nuclear pore distribution(GO:0031081) nuclear pore localization(GO:0051664)
0.1 0.2 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.1 0.2 GO:0072334 UDP-galactose transport(GO:0015785) UDP-galactose transmembrane transport(GO:0072334)
0.1 0.3 GO:0051684 maintenance of Golgi location(GO:0051684)
0.1 0.4 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.1 0.2 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 0.2 GO:0007057 spindle assembly involved in female meiosis I(GO:0007057) positive regulation of oocyte maturation(GO:1900195)
0.1 0.9 GO:0002115 store-operated calcium entry(GO:0002115)
0.1 0.3 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.1 0.3 GO:1904744 positive regulation of telomeric DNA binding(GO:1904744)
0.1 0.4 GO:0038026 reelin-mediated signaling pathway(GO:0038026)
0.1 0.3 GO:0035617 stress granule disassembly(GO:0035617)
0.1 0.2 GO:0044805 late nucleophagy(GO:0044805)
0.1 0.4 GO:0046654 tetrahydrofolate biosynthetic process(GO:0046654)
0.0 0.2 GO:0060830 ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
0.0 0.3 GO:0055129 L-proline biosynthetic process(GO:0055129)
0.0 1.1 GO:0006999 nuclear pore organization(GO:0006999)
0.0 0.1 GO:0018307 enzyme active site formation(GO:0018307)
0.0 0.5 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
0.0 0.3 GO:1903751 regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903750) negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903751)
0.0 0.5 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.0 0.2 GO:0045204 MAPK export from nucleus(GO:0045204)
0.0 0.4 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.2 GO:1903490 regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490)
0.0 0.4 GO:0071649 regulation of chemokine (C-C motif) ligand 5 production(GO:0071649)
0.0 0.3 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.0 0.3 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.0 0.2 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.0 0.2 GO:0044778 meiotic DNA integrity checkpoint(GO:0044778)
0.0 0.4 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0 0.1 GO:0002101 tRNA wobble cytosine modification(GO:0002101)
0.0 0.2 GO:0010825 positive regulation of centrosome duplication(GO:0010825)
0.0 0.2 GO:0090309 positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.0 0.2 GO:0030035 microspike assembly(GO:0030035)
0.0 0.7 GO:0031167 rRNA methylation(GO:0031167)
0.0 0.1 GO:1990167 protein K27-linked deubiquitination(GO:1990167) protein K33-linked deubiquitination(GO:1990168)
0.0 0.1 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
0.0 0.8 GO:0006744 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 0.2 GO:0048388 endosomal lumen acidification(GO:0048388)
0.0 0.6 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 0.2 GO:0035803 egg coat formation(GO:0035803)
0.0 0.2 GO:2001270 regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270) negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0 0.3 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.0 0.1 GO:0051892 negative regulation of cardioblast differentiation(GO:0051892) regulation of cardiac muscle cell myoblast differentiation(GO:2000690) negative regulation of cardiac muscle cell myoblast differentiation(GO:2000691)
0.0 0.4 GO:0022417 protein maturation by protein folding(GO:0022417)
0.0 0.5 GO:0000478 endonucleolytic cleavage involved in rRNA processing(GO:0000478)
0.0 0.9 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.3 GO:0070970 interleukin-2 secretion(GO:0070970)
0.0 0.3 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.0 0.1 GO:0007113 endomitotic cell cycle(GO:0007113)
0.0 1.0 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 0.2 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.0 0.2 GO:0090649 response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650) response to aldosterone(GO:1904044)
0.0 0.3 GO:0006983 ER overload response(GO:0006983)
0.0 0.4 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.1 GO:0042450 arginine biosynthetic process via ornithine(GO:0042450)
0.0 0.6 GO:0043651 linoleic acid metabolic process(GO:0043651)
0.0 0.1 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.0 0.7 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.0 0.8 GO:0034080 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0 0.1 GO:0035672 oligopeptide transmembrane transport(GO:0035672)
0.0 0.2 GO:0061470 T follicular helper cell differentiation(GO:0061470)
0.0 0.1 GO:0032417 positive regulation of sodium:proton antiporter activity(GO:0032417)
0.0 0.1 GO:0010793 regulation of mRNA export from nucleus(GO:0010793)
0.0 0.2 GO:0033182 regulation of histone ubiquitination(GO:0033182)
0.0 0.1 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.0 0.7 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.0 0.2 GO:0042262 DNA protection(GO:0042262)
0.0 0.4 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.0 0.0 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.0 0.2 GO:0051410 detoxification of nitrogen compound(GO:0051410)
0.0 0.1 GO:0032223 negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)
0.0 0.0 GO:0035928 rRNA import into mitochondrion(GO:0035928) rRNA transport(GO:0051029)
0.0 0.1 GO:0036369 transcription factor catabolic process(GO:0036369)
0.0 0.1 GO:1903568 negative regulation of protein localization to cilium(GO:1903565) regulation of protein localization to ciliary membrane(GO:1903567) negative regulation of protein localization to ciliary membrane(GO:1903568)
0.0 1.4 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 0.3 GO:0016081 synaptic vesicle docking(GO:0016081)
0.0 0.6 GO:0097150 neuronal stem cell population maintenance(GO:0097150)
0.0 0.3 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.0 0.3 GO:1901407 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407)
0.0 0.1 GO:0046931 pore complex assembly(GO:0046931)
0.0 0.1 GO:0018874 benzoate metabolic process(GO:0018874)
0.0 0.6 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.0 0.2 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.0 0.1 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.0 0.4 GO:0046852 positive regulation of bone resorption(GO:0045780) positive regulation of bone remodeling(GO:0046852)
0.0 0.1 GO:0090070 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.0 0.2 GO:0090261 positive regulation of inclusion body assembly(GO:0090261)
0.0 0.1 GO:0033152 immunoglobulin V(D)J recombination(GO:0033152)
0.0 0.3 GO:2000210 positive regulation of anoikis(GO:2000210)
0.0 0.2 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.0 0.7 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.2 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0 0.1 GO:0035621 ER to Golgi ceramide transport(GO:0035621)
0.0 0.2 GO:0016926 protein desumoylation(GO:0016926)
0.0 0.1 GO:0000957 mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
0.0 0.2 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 0.0 GO:2000820 negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000820)
0.0 0.2 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.0 0.0 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.0 0.1 GO:0061084 regulation of protein refolding(GO:0061083) negative regulation of protein refolding(GO:0061084)
0.0 0.1 GO:0061588 calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylserine scrambling(GO:0061589) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591)
0.0 0.5 GO:0000042 protein targeting to Golgi(GO:0000042)
0.0 0.4 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 0.2 GO:1900364 negative regulation of mRNA polyadenylation(GO:1900364)
0.0 0.7 GO:0017004 cytochrome complex assembly(GO:0017004)
0.0 0.2 GO:0098887 neurotransmitter receptor transport, endosome to postsynaptic membrane(GO:0098887)
0.0 0.1 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0 0.1 GO:0051418 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.0 0.2 GO:0000154 rRNA modification(GO:0000154)
0.0 0.2 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0 0.2 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.2 GO:0045835 negative regulation of meiotic nuclear division(GO:0045835)
0.0 0.1 GO:0034227 tRNA thio-modification(GO:0034227)
0.0 0.5 GO:0044458 motile cilium assembly(GO:0044458)
0.0 0.1 GO:0061734 parkin-mediated mitophagy in response to mitochondrial depolarization(GO:0061734)
0.0 0.3 GO:0070914 UV-damage excision repair(GO:0070914)
0.0 0.2 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 0.1 GO:0033601 positive regulation of mammary gland epithelial cell proliferation(GO:0033601)
0.0 0.3 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.0 0.0 GO:0061052 negative regulation of cell growth involved in cardiac muscle cell development(GO:0061052)
0.0 0.1 GO:0060339 adenosine to inosine editing(GO:0006382) negative regulation of type I interferon-mediated signaling pathway(GO:0060339)
0.0 0.1 GO:2000643 positive regulation of early endosome to late endosome transport(GO:2000643)
0.0 0.1 GO:0051096 positive regulation of helicase activity(GO:0051096)
0.0 0.2 GO:0035860 glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.0 0.5 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.1 GO:1901908 diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.0 1.8 GO:0007062 sister chromatid cohesion(GO:0007062)
0.0 0.2 GO:0098780 response to mitochondrial depolarisation(GO:0098780)
0.0 0.1 GO:0045040 protein import into mitochondrial outer membrane(GO:0045040)
0.0 0.1 GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
0.0 0.1 GO:2000035 regulation of stem cell division(GO:2000035)
0.0 0.4 GO:0060008 Sertoli cell differentiation(GO:0060008)
0.0 0.1 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.0 0.2 GO:0008298 intracellular mRNA localization(GO:0008298)
0.0 0.1 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 0.2 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.0 0.3 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.0 0.1 GO:0001522 pseudouridine synthesis(GO:0001522)
0.0 0.5 GO:0030490 maturation of SSU-rRNA(GO:0030490)
0.0 0.4 GO:0031116 positive regulation of microtubule polymerization(GO:0031116)
0.0 0.1 GO:0090151 establishment of protein localization to mitochondrial membrane(GO:0090151)
0.0 0.0 GO:0034140 negative regulation of toll-like receptor 3 signaling pathway(GO:0034140)
0.0 0.7 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.0 0.1 GO:0071105 response to interleukin-11(GO:0071105)
0.0 0.0 GO:0009443 pyridoxal 5'-phosphate salvage(GO:0009443)
0.0 0.1 GO:1902378 vestibulocochlear nerve structural organization(GO:0021649) positive regulation of cytokine activity(GO:0060301) ganglion morphogenesis(GO:0061552) endothelial tip cell fate specification(GO:0097102) VEGF-activated neuropilin signaling pathway involved in axon guidance(GO:1902378) dorsal root ganglion morphogenesis(GO:1904835) otic placode development(GO:1905040)
0.0 0.5 GO:0006370 7-methylguanosine mRNA capping(GO:0006370)
0.0 0.2 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.1 GO:0060766 negative regulation of androgen receptor signaling pathway(GO:0060766)
0.0 0.1 GO:0090400 stress-induced premature senescence(GO:0090400)
0.0 0.3 GO:0006337 nucleosome disassembly(GO:0006337)
0.0 0.1 GO:2001013 epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.0 0.2 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 0.2 GO:0051775 response to redox state(GO:0051775)
0.0 0.4 GO:0048025 negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.0 0.1 GO:1900864 mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864)
0.0 0.1 GO:0016998 acrosome assembly(GO:0001675) cell wall macromolecule catabolic process(GO:0016998)
0.0 0.1 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.0 0.1 GO:0006930 substrate-dependent cell migration, cell extension(GO:0006930)
0.0 0.0 GO:0007198 adenylate cyclase-inhibiting serotonin receptor signaling pathway(GO:0007198)
0.0 0.1 GO:0000733 DNA strand renaturation(GO:0000733)
0.0 0.1 GO:0060161 positive regulation of dopamine receptor signaling pathway(GO:0060161)
0.0 0.4 GO:1903146 regulation of mitophagy(GO:1903146)
0.0 0.1 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
0.0 0.0 GO:1905244 fasciculation of motor neuron axon(GO:0097156) regulation of modification of synaptic structure(GO:1905244)
0.0 0.2 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.0 GO:0048633 positive regulation of skeletal muscle tissue growth(GO:0048633)
0.0 0.4 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.0 0.1 GO:0006564 L-serine biosynthetic process(GO:0006564)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.8 GO:1990423 RZZ complex(GO:1990423)
0.1 0.7 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942) Ndc80 complex(GO:0031262)
0.1 1.0 GO:0070761 PCAF complex(GO:0000125) pre-snoRNP complex(GO:0070761)
0.1 0.3 GO:0070557 PCNA-p21 complex(GO:0070557)
0.1 0.3 GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.1 0.4 GO:0033186 CAF-1 complex(GO:0033186)
0.1 0.1 GO:0036387 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
0.1 0.7 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.1 0.4 GO:0005846 nuclear cap binding complex(GO:0005846)
0.1 0.4 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.1 1.5 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.1 0.7 GO:0098560 cytoplasmic side of late endosome membrane(GO:0098560)
0.1 0.7 GO:0000778 condensed nuclear chromosome kinetochore(GO:0000778)
0.1 1.3 GO:0042555 MCM complex(GO:0042555)
0.1 0.4 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
0.1 0.2 GO:0031372 UBC13-MMS2 complex(GO:0031372)
0.1 0.5 GO:0043564 Ku70:Ku80 complex(GO:0043564)
0.1 0.4 GO:0097149 centralspindlin complex(GO:0097149)
0.1 0.7 GO:0000796 condensin complex(GO:0000796)
0.1 0.4 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958) DNA ligase IV complex(GO:0032807)
0.1 0.4 GO:0072589 box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
0.1 0.2 GO:0032044 DSIF complex(GO:0032044)
0.1 0.3 GO:0098536 deuterosome(GO:0098536)
0.1 1.6 GO:0071004 U2-type prespliceosome(GO:0071004)
0.1 0.3 GO:1990769 proximal neuron projection(GO:1990769)
0.1 0.3 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.1 1.0 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1 0.2 GO:0097134 Y chromosome(GO:0000806) cyclin A2-CDK2 complex(GO:0097124) cyclin E1-CDK2 complex(GO:0097134)
0.1 0.2 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.0 0.1 GO:0071141 SMAD protein complex(GO:0071141)
0.0 0.3 GO:0005663 DNA replication factor C complex(GO:0005663)
0.0 0.6 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.2 GO:0044393 microspike(GO:0044393)
0.0 0.1 GO:0005715 late recombination nodule(GO:0005715)
0.0 0.2 GO:0001674 female germ cell nucleus(GO:0001674)
0.0 0.2 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.5 GO:0031298 replication fork protection complex(GO:0031298)
0.0 0.2 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.0 0.8 GO:0005732 small nucleolar ribonucleoprotein complex(GO:0005732)
0.0 0.2 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.0 0.5 GO:0031595 nuclear proteasome complex(GO:0031595)
0.0 0.9 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.2 GO:0044530 supraspliceosomal complex(GO:0044530)
0.0 0.1 GO:0070985 TFIIK complex(GO:0070985)
0.0 0.2 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.0 0.3 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.1 GO:0055087 Ski complex(GO:0055087)
0.0 0.4 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.3 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.5 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 0.1 GO:0033263 CORVET complex(GO:0033263)
0.0 0.2 GO:0097452 GAIT complex(GO:0097452)
0.0 0.1 GO:0071001 U4/U6 snRNP(GO:0071001)
0.0 1.9 GO:0030684 preribosome(GO:0030684)
0.0 0.2 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.1 GO:0008275 gamma-tubulin small complex(GO:0008275)
0.0 0.8 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.2 GO:0098845 postsynaptic endosome(GO:0098845)
0.0 0.2 GO:0071010 prespliceosome(GO:0071010)
0.0 0.2 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.1 GO:0010009 cytoplasmic side of endosome membrane(GO:0010009)
0.0 0.6 GO:0051233 spindle midzone(GO:0051233)
0.0 0.1 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.0 0.3 GO:0001741 XY body(GO:0001741)
0.0 0.1 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.0 0.6 GO:0043209 myelin sheath(GO:0043209)
0.0 0.1 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.0 0.4 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.2 GO:0030896 checkpoint clamp complex(GO:0030896)
0.0 0.4 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.2 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 0.2 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.1 GO:0097196 Shu complex(GO:0097196)
0.0 0.2 GO:0045180 basal cortex(GO:0045180)
0.0 0.1 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.0 0.3 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.1 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.0 0.4 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.1 GO:0044423 virion(GO:0019012) virion part(GO:0044423)
0.0 0.1 GO:0002177 manchette(GO:0002177)
0.0 0.0 GO:0000814 ESCRT II complex(GO:0000814)
0.0 0.2 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.2 GO:0034464 BBSome(GO:0034464)
0.0 0.1 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.1 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.1 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 0.9 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.1 GO:0070765 gamma-secretase complex(GO:0070765)
0.0 0.2 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 0.8 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 0.7 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.1 GO:0032437 cuticular plate(GO:0032437)
0.0 0.3 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.1 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.6 GO:0045171 intercellular bridge(GO:0045171)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0043739 G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739)
0.2 0.6 GO:0047273 galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity(GO:0047273)
0.2 0.7 GO:0035650 AP-1 adaptor complex binding(GO:0035650)
0.2 0.5 GO:0016435 rRNA (guanine) methyltransferase activity(GO:0016435)
0.1 0.4 GO:0035539 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity(GO:0008413) 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity(GO:0035539)
0.1 0.4 GO:0070283 lipoate synthase activity(GO:0016992) radical SAM enzyme activity(GO:0070283)
0.1 0.7 GO:0070363 mitochondrial light strand promoter sense binding(GO:0070363)
0.1 0.4 GO:0015091 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.1 0.6 GO:0016215 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.1 0.7 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.1 0.3 GO:0050567 glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
0.1 0.4 GO:0038025 reelin receptor activity(GO:0038025)
0.1 0.3 GO:0016838 carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.1 0.3 GO:0004087 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.1 0.5 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.1 0.3 GO:0004827 glutamate-tRNA ligase activity(GO:0004818) proline-tRNA ligase activity(GO:0004827)
0.1 0.4 GO:0016160 amylase activity(GO:0016160)
0.1 0.4 GO:0004832 valine-tRNA ligase activity(GO:0004832)
0.1 1.5 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 0.3 GO:0032450 oligo-1,6-glucosidase activity(GO:0004574) maltose alpha-glucosidase activity(GO:0032450)
0.1 0.3 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.1 0.3 GO:0030337 DNA polymerase processivity factor activity(GO:0030337)
0.1 0.8 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.1 0.4 GO:0016882 cyclo-ligase activity(GO:0016882)
0.1 0.4 GO:0051032 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.1 0.3 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.1 0.3 GO:0004066 asparagine synthase (glutamine-hydrolyzing) activity(GO:0004066)
0.1 0.2 GO:0061752 telomeric repeat-containing RNA binding(GO:0061752)
0.1 1.1 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.1 0.2 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.1 0.3 GO:0070568 guanylyltransferase activity(GO:0070568)
0.1 0.2 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.1 0.2 GO:0031531 thyrotropin-releasing hormone receptor binding(GO:0031531)
0.1 0.4 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.1 0.3 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.1 0.9 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.1 0.2 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.1 0.4 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.2 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.0 0.6 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.2 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0 0.3 GO:0050733 RS domain binding(GO:0050733)
0.0 0.8 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.2 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0 0.1 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.0 0.1 GO:0035500 MH2 domain binding(GO:0035500)
0.0 0.4 GO:0019238 cyclohydrolase activity(GO:0019238)
0.0 0.4 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 0.8 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.4 GO:0009008 DNA-methyltransferase activity(GO:0009008)
0.0 0.1 GO:0015235 cobalamin transporter activity(GO:0015235)
0.0 0.4 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.0 0.2 GO:0001054 RNA polymerase I activity(GO:0001054)
0.0 0.5 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.0 0.2 GO:0030151 molybdenum ion binding(GO:0030151)
0.0 0.4 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.9 GO:0001056 RNA polymerase III activity(GO:0001056)
0.0 0.2 GO:0000405 bubble DNA binding(GO:0000405)
0.0 0.4 GO:0003910 DNA ligase (ATP) activity(GO:0003910)
0.0 0.3 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.1 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0 0.6 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.1 GO:0032427 GBD domain binding(GO:0032427)
0.0 0.1 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
0.0 1.5 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 1.0 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.1 GO:0031177 acyl binding(GO:0000035) phosphopantetheine binding(GO:0031177)
0.0 1.5 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.0 0.1 GO:0030627 pre-mRNA 5'-splice site binding(GO:0030627)
0.0 0.2 GO:0045569 TRAIL binding(GO:0045569)
0.0 0.3 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.0 0.2 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.0 0.3 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.0 0.1 GO:0035034 histone acetyltransferase regulator activity(GO:0035034)
0.0 1.4 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.5 GO:0015250 water channel activity(GO:0015250)
0.0 0.2 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.0 0.8 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.4 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.4 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.2 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.0 0.2 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.2 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 0.2 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 0.2 GO:0032051 clathrin light chain binding(GO:0032051)
0.0 0.2 GO:0030614 oxidoreductase activity, acting on phosphorus or arsenic in donors(GO:0030613) oxidoreductase activity, acting on phosphorus or arsenic in donors, disulfide as acceptor(GO:0030614)
0.0 0.4 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.7 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.1 GO:0004792 thiosulfate sulfurtransferase activity(GO:0004792)
0.0 0.4 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.2 GO:0032190 acrosin binding(GO:0032190)
0.0 0.1 GO:0051538 3 iron, 4 sulfur cluster binding(GO:0051538)
0.0 0.2 GO:1990446 U1 snRNP binding(GO:1990446)
0.0 0.2 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 0.4 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.0 0.1 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0 0.2 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
0.0 0.2 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.0 0.1 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.0 0.5 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.0 0.4 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.5 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.1 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.6 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.1 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.0 0.1 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.3 GO:0008649 rRNA methyltransferase activity(GO:0008649)
0.0 0.3 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.0 0.1 GO:0032137 guanine/thymine mispair binding(GO:0032137)
0.0 0.5 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.2 GO:0008312 7S RNA binding(GO:0008312)
0.0 0.1 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.0 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.2 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.0 0.1 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 0.1 GO:0015926 glucosidase activity(GO:0015926)
0.0 0.1 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 0.1 GO:0001515 opioid peptide activity(GO:0001515)
0.0 0.1 GO:0034511 U3 snoRNA binding(GO:0034511)
0.0 0.1 GO:0070644 vitamin D response element binding(GO:0070644)
0.0 0.1 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.1 GO:0017089 glycolipid transporter activity(GO:0017089)
0.0 0.0 GO:0000403 Y-form DNA binding(GO:0000403)
0.0 0.1 GO:0000298 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848)
0.0 0.1 GO:0035174 histone serine kinase activity(GO:0035174)
0.0 0.1 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.3 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.1 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.1 GO:0030621 U4 snRNA binding(GO:0030621)
0.0 0.2 GO:0019789 SUMO transferase activity(GO:0019789)
0.0 0.1 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.9 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.6 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.0 GO:0048408 epidermal growth factor binding(GO:0048408)
0.0 0.1 GO:0008175 tRNA methyltransferase activity(GO:0008175)
0.0 0.4 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.0 GO:0008478 pyridoxal kinase activity(GO:0008478) lithium ion binding(GO:0031403)
0.0 0.1 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.1 GO:0005329 dopamine transmembrane transporter activity(GO:0005329)
0.0 0.3 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.0 0.7 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.4 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.1 GO:0016842 amidine-lyase activity(GO:0016842)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.7 PID_TCR_CALCIUM_PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.4 PID_RANBP2_PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.8 PID_ERBB_NETWORK_PATHWAY ErbB receptor signaling network
0.0 1.2 PID_BARD1_PATHWAY BARD1 signaling events
0.0 1.0 PID_MYC_PATHWAY C-MYC pathway
0.0 1.4 PID_AURORA_B_PATHWAY Aurora B signaling
0.0 0.8 ST_GRANULE_CELL_SURVIVAL_PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 1.4 PID_MYC_ACTIV_PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.6 PID_FANCONI_PATHWAY Fanconi anemia pathway
0.0 0.3 PID_S1P_META_PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 0.4 PID_FOXM1_PATHWAY FOXM1 transcription factor network
0.0 0.3 PID_HDAC_CLASSIII_PATHWAY Signaling events mediated by HDAC Class III

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 REACTOME_UNWINDING_OF_DNA Genes involved in Unwinding of DNA
0.1 0.9 REACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.1 0.3 REACTOME_ABORTIVE_ELONGATION_OF_HIV1_TRANSCRIPT_IN_THE_ABSENCE_OF_TAT Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat
0.1 0.4 REACTOME_REMOVAL_OF_THE_FLAP_INTERMEDIATE_FROM_THE_C_STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.8 REACTOME_INTEGRATION_OF_PROVIRUS Genes involved in Integration of provirus
0.0 1.8 REACTOME_ACTIVATION_OF_ATR_IN_RESPONSE_TO_REPLICATION_STRESS Genes involved in Activation of ATR in response to replication stress
0.0 1.0 REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.8 REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 2.2 REACTOME_TRANSPORT_OF_MATURE_MRNA_DERIVED_FROM_AN_INTRONLESS_TRANSCRIPT Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.0 0.4 REACTOME_DIGESTION_OF_DIETARY_CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.7 REACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.9 REACTOME_RNA_POL_III_CHAIN_ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.6 REACTOME_BASE_FREE_SUGAR_PHOSPHATE_REMOVAL_VIA_THE_SINGLE_NUCLEOTIDE_REPLACEMENT_PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 0.6 REACTOME_SYNTHESIS_OF_SUBSTRATES_IN_N_GLYCAN_BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.5 REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.4 REACTOME_PLATELET_SENSITIZATION_BY_LDL Genes involved in Platelet sensitization by LDL
0.0 0.4 REACTOME_MRNA_DECAY_BY_3_TO_5_EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 1.4 REACTOME_MRNA_SPLICING_MINOR_PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 3.4 REACTOME_MITOTIC_PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 1.1 REACTOME_RNA_POL_II_TRANSCRIPTION_PRE_INITIATION_AND_PROMOTER_OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.8 REACTOME_AMINO_ACID_SYNTHESIS_AND_INTERCONVERSION_TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.3 REACTOME_NEGATIVE_REGULATION_OF_THE_PI3K_AKT_NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.3 REACTOME_G2_M_CHECKPOINTS Genes involved in G2/M Checkpoints
0.0 0.0 REACTOME_MRNA_CAPPING Genes involved in mRNA Capping
0.0 0.4 REACTOME_ALPHA_LINOLENIC_ACID_ALA_METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.7 REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.7 REACTOME_PYRIMIDINE_METABOLISM Genes involved in Pyrimidine metabolism
0.0 2.3 REACTOME_REGULATION_OF_MRNA_STABILITY_BY_PROTEINS_THAT_BIND_AU_RICH_ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.0 0.7 REACTOME_PREFOLDIN_MEDIATED_TRANSFER_OF_SUBSTRATE_TO_CCT_TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.0 0.2 REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION_IN_TLR7_8_OR_9_SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 0.6 REACTOME_TRANSFERRIN_ENDOCYTOSIS_AND_RECYCLING Genes involved in Transferrin endocytosis and recycling
0.0 0.9 REACTOME_RNA_POL_I_RNA_POL_III_AND_MITOCHONDRIAL_TRANSCRIPTION Genes involved in RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription
0.0 0.2 REACTOME_BIOSYNTHESIS_OF_THE_N_GLYCAN_PRECURSOR_DOLICHOL_LIPID_LINKED_OLIGOSACCHARIDE_LLO_AND_TRANSFER_TO_A_NASCENT_PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.4 REACTOME_ZINC_TRANSPORTERS Genes involved in Zinc transporters
0.0 0.4 REACTOME_APC_C_CDH1_MEDIATED_DEGRADATION_OF_CDC20_AND_OTHER_APC_C_CDH1_TARGETED_PROTEINS_IN_LATE_MITOSIS_EARLY_G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.0 0.3 REACTOME_TETRAHYDROBIOPTERIN_BH4_SYNTHESIS_RECYCLING_SALVAGE_AND_REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.3 REACTOME_EXTENSION_OF_TELOMERES Genes involved in Extension of Telomeres
0.0 0.4 REACTOME_CHOLESTEROL_BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.4 REACTOME_KINESINS Genes involved in Kinesins
0.0 0.8 REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.3 REACTOME_FANCONI_ANEMIA_PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.1 REACTOME_RECRUITMENT_OF_NUMA_TO_MITOTIC_CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes