Motif ID: GTF2I

Z-value: 0.976


Transcription factors associated with GTF2I:

Gene SymbolEntrez IDGene Name
GTF2I ENSG00000077809.8 GTF2I

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
GTF2Ihg19_v2_chr7_+_74072011_740721190.711.1e-04Click!


Activity profile for motif GTF2I.

activity profile for motif GTF2I


Sorted Z-values histogram for motif GTF2I

Sorted Z-values for motif GTF2I



Network of associatons between targets according to the STRING database.



First level regulatory network of GTF2I

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr16_-_52580920 2.860 ENST00000219746.9
TOX3
TOX high mobility group box family member 3
chr5_-_121413974 2.675 ENST00000231004.4
LOX
lysyl oxidase
chr1_-_109656439 2.463 ENST00000369949.4
C1orf194
chromosome 1 open reading frame 194
chr2_+_85981008 2.257 ENST00000306279.3
ATOH8
atonal homolog 8 (Drosophila)
chr4_+_30721968 2.215 ENST00000361762.2
PCDH7
protocadherin 7
chr11_-_46142615 1.997 ENST00000529734.1
ENST00000323180.6
PHF21A

PHD finger protein 21A

chr18_-_45935663 1.890 ENST00000589194.1
ENST00000591279.1
ENST00000590855.1
ENST00000587107.1
ENST00000588970.1
ENST00000586525.1
ENST00000592387.1
ENST00000590800.1
ZBTB7C







zinc finger and BTB domain containing 7C







chr5_-_81046904 1.826 ENST00000515395.1
SSBP2
single-stranded DNA binding protein 2
chr11_-_46142505 1.799 ENST00000524497.1
ENST00000418153.2
PHF21A

PHD finger protein 21A

chr14_-_54423529 1.657 ENST00000245451.4
ENST00000559087.1
BMP4

bone morphogenetic protein 4

chr13_-_36705425 1.649 ENST00000255448.4
ENST00000360631.3
ENST00000379892.4
DCLK1


doublecortin-like kinase 1


chr14_-_21270995 1.645 ENST00000555698.1
ENST00000397970.4
ENST00000340900.3
RNASE1


ribonuclease, RNase A family, 1 (pancreatic)


chr14_-_61190754 1.631 ENST00000216513.4
SIX4
SIX homeobox 4
chr19_+_55888186 1.630 ENST00000291934.3
TMEM190
transmembrane protein 190
chr5_-_81046841 1.597 ENST00000509013.2
ENST00000505980.1
ENST00000509053.1
SSBP2


single-stranded DNA binding protein 2


chr19_+_35629702 1.593 ENST00000351325.4
FXYD1
FXYD domain containing ion transport regulator 1
chr17_+_72733350 1.577 ENST00000392613.5
ENST00000392612.3
ENST00000392610.1
RAB37


RAB37, member RAS oncogene family


chr20_+_36531499 1.536 ENST00000373458.3
ENST00000373461.4
ENST00000373459.4
VSTM2L


V-set and transmembrane domain containing 2 like


chr4_-_168155730 1.499 ENST00000502330.1
ENST00000357154.3
SPOCK3

sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3

chr1_+_183605200 1.454 ENST00000304685.4
RGL1
ral guanine nucleotide dissociation stimulator-like 1
chr7_+_73442487 1.421 ENST00000380575.4
ENST00000380584.4
ENST00000458204.1
ENST00000357036.5
ENST00000417091.1
ENST00000429192.1
ENST00000442310.1
ENST00000380553.4
ENST00000380576.5
ENST00000428787.1
ENST00000320399.6
ELN










elastin










chr2_-_19558373 1.354 ENST00000272223.2
OSR1
odd-skipped related transciption factor 1
chr4_-_168155700 1.346 ENST00000357545.4
ENST00000512648.1
SPOCK3

sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3

chr6_-_32920794 1.300 ENST00000395305.3
ENST00000395303.3
ENST00000374843.4
ENST00000429234.1
HLA-DMA


XXbac-BPG181M17.5
major histocompatibility complex, class II, DM alpha


Uncharacterized protein
chr3_+_160473996 1.291 ENST00000498165.1
PPM1L
protein phosphatase, Mg2+/Mn2+ dependent, 1L
chr16_+_69599899 1.266 ENST00000567239.1
NFAT5
nuclear factor of activated T-cells 5, tonicity-responsive
chr6_+_19837592 1.226 ENST00000378700.3
ID4
inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
chr12_+_46123682 1.220 ENST00000422737.1
ARID2
AT rich interactive domain 2 (ARID, RFX-like)
chr7_+_73442422 1.208 ENST00000358929.4
ENST00000431562.1
ENST00000320492.7
ENST00000438906.1
ELN



elastin



chr17_-_7120498 1.204 ENST00000485100.1
DLG4
discs, large homolog 4 (Drosophila)
chr1_+_205538105 1.158 ENST00000367147.4
ENST00000539267.1
MFSD4

major facilitator superfamily domain containing 4

chr19_+_35630022 1.112 ENST00000589209.1
FXYD1
FXYD domain containing ion transport regulator 1
chr20_-_55841398 1.104 ENST00000395864.3
BMP7
bone morphogenetic protein 7
chr12_-_50222187 1.078 ENST00000335999.6
NCKAP5L
NCK-associated protein 5-like
chr4_-_168155417 1.066 ENST00000511269.1
ENST00000506697.1
ENST00000512042.1
SPOCK3


sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3


chr16_+_69600058 1.064 ENST00000393742.2
NFAT5
nuclear factor of activated T-cells 5, tonicity-responsive
chr7_+_73442102 1.053 ENST00000445912.1
ENST00000252034.7
ELN

elastin

chr6_+_149068464 1.052 ENST00000367463.4
UST
uronyl-2-sulfotransferase
chr6_-_90121789 1.046 ENST00000359203.3
RRAGD
Ras-related GTP binding D
chr5_-_81046922 1.042 ENST00000514493.1
ENST00000320672.4
SSBP2

single-stranded DNA binding protein 2

chr18_-_45663666 1.041 ENST00000535628.2
ZBTB7C
zinc finger and BTB domain containing 7C
chr17_-_42276574 1.030 ENST00000589805.1
ATXN7L3
ataxin 7-like 3
chr2_-_174828892 1.014 ENST00000418194.2
SP3
Sp3 transcription factor
chr7_+_121513143 1.003 ENST00000393386.2
PTPRZ1
protein tyrosine phosphatase, receptor-type, Z polypeptide 1
chr2_+_8822113 1.002 ENST00000396290.1
ENST00000331129.3
ID2

inhibitor of DNA binding 2, dominant negative helix-loop-helix protein

chr6_-_90121938 0.982 ENST00000369415.4
RRAGD
Ras-related GTP binding D
chr16_+_69599861 0.981 ENST00000354436.2
NFAT5
nuclear factor of activated T-cells 5, tonicity-responsive
chr19_+_50094866 0.981 ENST00000418929.2
PRR12
proline rich 12
chr9_-_124991124 0.980 ENST00000394319.4
ENST00000340587.3
LHX6

LIM homeobox 6

chr1_+_109656719 0.980 ENST00000457623.2
ENST00000529753.1
KIAA1324

KIAA1324

chr12_+_102091400 0.979 ENST00000229266.3
ENST00000549872.1
CHPT1

choline phosphotransferase 1

chr3_-_131753830 0.967 ENST00000429747.1
CPNE4
copine IV
chr7_+_100612904 0.967 ENST00000379442.3
ENST00000536621.1
MUC12

mucin 12, cell surface associated

chr1_-_167906020 0.962 ENST00000458574.1
MPC2
mitochondrial pyruvate carrier 2
chr4_-_168155300 0.952 ENST00000541637.1
SPOCK3
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chr12_+_6930703 0.950 ENST00000311268.3
GPR162
G protein-coupled receptor 162
chr4_+_106816644 0.948 ENST00000506666.1
ENST00000503451.1
NPNT

nephronectin

chr17_+_73472575 0.936 ENST00000375248.5
KIAA0195
KIAA0195
chr20_+_9049682 0.929 ENST00000334005.3
ENST00000378473.3
PLCB4

phospholipase C, beta 4

chr9_-_20622478 0.928 ENST00000355930.6
ENST00000380338.4
MLLT3

myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3

chr1_-_223537475 0.921 ENST00000344029.6
ENST00000494793.2
ENST00000366878.4
ENST00000366877.3
SUSD4



sushi domain containing 4



chr12_+_6930813 0.921 ENST00000428545.2
GPR162
G protein-coupled receptor 162
chr11_-_106889157 0.909 ENST00000282249.2
GUCY1A2
guanylate cyclase 1, soluble, alpha 2
chr1_-_223537401 0.906 ENST00000343846.3
ENST00000454695.2
ENST00000484758.2
SUSD4


sushi domain containing 4


chr5_-_159739532 0.898 ENST00000520748.1
ENST00000393977.3
ENST00000257536.7
CCNJL


cyclin J-like


chr2_+_230787213 0.894 ENST00000409992.1
FBXO36
F-box protein 36
chr3_+_238273 0.890 ENST00000256509.2
CHL1
cell adhesion molecule L1-like
chr10_+_94833642 0.880 ENST00000224356.4
ENST00000394139.1
CYP26A1

cytochrome P450, family 26, subfamily A, polypeptide 1

chr5_+_139027877 0.874 ENST00000302517.3
CXXC5
CXXC finger protein 5
chr15_-_49255632 0.866 ENST00000332408.4
SHC4
SHC (Src homology 2 domain containing) family, member 4
chr1_+_61330931 0.851 ENST00000371191.1
NFIA
nuclear factor I/A
chr2_+_230787201 0.850 ENST00000283946.3
FBXO36
F-box protein 36
chr11_+_13299186 0.850 ENST00000527998.1
ENST00000396441.3
ENST00000533520.1
ENST00000529825.1
ENST00000389707.4
ENST00000401424.1
ENST00000529388.1
ENST00000530357.1
ENST00000403290.1
ENST00000361003.4
ENST00000389708.3
ENST00000403510.3
ENST00000482049.1
ARNTL












aryl hydrocarbon receptor nuclear translocator-like












chr3_+_3841108 0.821 ENST00000319331.3
LRRN1
leucine rich repeat neuronal 1
chr7_+_73442457 0.809 ENST00000438880.1
ENST00000414324.1
ENST00000380562.4
ELN


elastin


chr5_-_111092930 0.806 ENST00000257435.7
NREP
neuronal regeneration related protein
chr11_+_46316677 0.803 ENST00000534787.1
CREB3L1
cAMP responsive element binding protein 3-like 1
chr19_-_14316980 0.801 ENST00000361434.3
ENST00000340736.6
LPHN1

latrophilin 1

chr2_+_149402553 0.794 ENST00000258484.6
ENST00000409654.1
EPC2

enhancer of polycomb homolog 2 (Drosophila)

chr22_-_50970506 0.791 ENST00000428989.2
ENST00000403326.1
ODF3B

outer dense fiber of sperm tails 3B

chr6_-_111804905 0.777 ENST00000358835.3
ENST00000435970.1
REV3L

REV3-like, polymerase (DNA directed), zeta, catalytic subunit

chr1_+_109656579 0.776 ENST00000526264.1
ENST00000369939.3
KIAA1324

KIAA1324

chr15_-_37392703 0.771 ENST00000382766.2
ENST00000444725.1
MEIS2

Meis homeobox 2

chr1_-_167906277 0.757 ENST00000271373.4
MPC2
mitochondrial pyruvate carrier 2
chr1_+_211433275 0.755 ENST00000367005.4
RCOR3
REST corepressor 3
chr11_+_61276214 0.745 ENST00000378075.2
LRRC10B
leucine rich repeat containing 10B
chr1_+_164528866 0.726 ENST00000420696.2
PBX1
pre-B-cell leukemia homeobox 1
chr20_+_44637526 0.722 ENST00000372330.3
MMP9
matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
chr13_+_50589390 0.718 ENST00000360473.4
ENST00000312942.1
KCNRG

potassium channel regulator

chr5_-_111093167 0.711 ENST00000446294.2
ENST00000419114.2
NREP

neuronal regeneration related protein

chr15_+_81426588 0.710 ENST00000286732.4
C15orf26
chromosome 15 open reading frame 26
chr4_-_168155577 0.707 ENST00000541354.1
ENST00000509854.1
ENST00000512681.1
ENST00000421836.2
ENST00000510741.1
ENST00000510403.1
SPOCK3





sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3





chr12_+_113587558 0.707 ENST00000335621.6
CCDC42B
coiled-coil domain containing 42B
chr18_+_46065393 0.704 ENST00000256413.3
CTIF
CBP80/20-dependent translation initiation factor
chr6_+_36164487 0.695 ENST00000357641.6
BRPF3
bromodomain and PHD finger containing, 3
chr10_+_99079008 0.695 ENST00000371021.3
FRAT1
frequently rearranged in advanced T-cell lymphomas
chr20_-_55841662 0.689 ENST00000395863.3
ENST00000450594.2
BMP7

bone morphogenetic protein 7

chr4_+_55524085 0.683 ENST00000412167.2
ENST00000288135.5
KIT

v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog

chr2_+_114384806 0.680 ENST00000393167.3
ENST00000409842.1
ENST00000413545.1
ENST00000393165.3
ENST00000393166.3
ENST00000409875.1
ENST00000376439.3
RABL2A






RAB, member of RAS oncogene family-like 2A






chr20_+_44098346 0.677 ENST00000372676.3
WFDC2
WAP four-disulfide core domain 2
chr9_-_89562104 0.671 ENST00000298743.7
GAS1
growth arrest-specific 1
chr21_-_47738112 0.665 ENST00000417060.1
C21orf58
chromosome 21 open reading frame 58
chr1_-_223536679 0.663 ENST00000608996.1
SUSD4
sushi domain containing 4
chr6_-_29595779 0.657 ENST00000355973.3
ENST00000377012.4
GABBR1

gamma-aminobutyric acid (GABA) B receptor, 1

chr9_+_71320557 0.654 ENST00000541509.1
PIP5K1B
phosphatidylinositol-4-phosphate 5-kinase, type I, beta
chr20_-_21494654 0.654 ENST00000377142.4
NKX2-2
NK2 homeobox 2
chr12_+_6930964 0.649 ENST00000382315.3
GPR162
G protein-coupled receptor 162
chr22_-_27620603 0.648 ENST00000418271.1
ENST00000444114.1
RP5-1172A22.1

RP5-1172A22.1

chr4_-_168155169 0.641 ENST00000534949.1
ENST00000535728.1
SPOCK3

sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3

chrX_-_38186811 0.631 ENST00000318842.7
RPGR
retinitis pigmentosa GTPase regulator
chr19_+_35630344 0.621 ENST00000455515.2
FXYD1
FXYD domain containing ion transport regulator 1
chr5_-_111092873 0.621 ENST00000509025.1
ENST00000515855.1
NREP

neuronal regeneration related protein

chr5_-_146833485 0.612 ENST00000398514.3
DPYSL3
dihydropyrimidinase-like 3
chr6_-_31846744 0.611 ENST00000414427.1
ENST00000229729.6
ENST00000375562.4
SLC44A4


solute carrier family 44, member 4


chr6_-_31745037 0.610 ENST00000375688.4
VWA7
von Willebrand factor A domain containing 7
chr6_-_31745085 0.608 ENST00000375686.3
ENST00000447450.1
VWA7

von Willebrand factor A domain containing 7

chrX_-_38186775 0.604 ENST00000339363.3
ENST00000309513.3
ENST00000338898.3
ENST00000342811.3
ENST00000378505.2
RPGR




retinitis pigmentosa GTPase regulator




chr14_+_23776167 0.601 ENST00000554635.1
ENST00000557008.1
BCL2L2
BCL2L2-PABPN1
BCL2-like 2
BCL2L2-PABPN1 readthrough
chr4_-_25864581 0.594 ENST00000399878.3
SEL1L3
sel-1 suppressor of lin-12-like 3 (C. elegans)
chr2_-_99757977 0.591 ENST00000355053.4
TSGA10
testis specific, 10
chr20_-_3154162 0.585 ENST00000360342.3
LZTS3
Homo sapiens leucine zipper, putative tumor suppressor family member 3 (LZTS3), mRNA.
chr10_+_104503727 0.583 ENST00000448841.1
WBP1L
WW domain binding protein 1-like
chr15_-_37392086 0.583 ENST00000561208.1
MEIS2
Meis homeobox 2
chr1_+_109102652 0.582 ENST00000370035.3
ENST00000405454.1
FAM102B

family with sequence similarity 102, member B

chr5_+_36876833 0.580 ENST00000282516.8
ENST00000448238.2
NIPBL

Nipped-B homolog (Drosophila)

chr2_+_189156721 0.579 ENST00000409927.1
ENST00000409805.1
GULP1

GULP, engulfment adaptor PTB domain containing 1

chr1_+_26438289 0.577 ENST00000374271.4
ENST00000374269.1
PDIK1L

PDLIM1 interacting kinase 1 like

chr6_-_20212630 0.574 ENST00000324607.7
ENST00000541730.1
ENST00000536798.1
MBOAT1


membrane bound O-acyltransferase domain containing 1


chr14_+_21538517 0.568 ENST00000298693.3
ARHGEF40
Rho guanine nucleotide exchange factor (GEF) 40
chr11_+_111789580 0.568 ENST00000278601.5
C11orf52
chromosome 11 open reading frame 52
chr12_+_46123448 0.568 ENST00000334344.6
ARID2
AT rich interactive domain 2 (ARID, RFX-like)
chr3_+_69812877 0.566 ENST00000457080.1
ENST00000328528.6
MITF

microphthalmia-associated transcription factor

chr14_+_23776024 0.566 ENST00000557236.1
ENST00000557579.1
ENST00000553781.1
ENST00000556100.1
BCL2L2

BCL2L2-PABPN1

BCL2-like 2

BCL2L2-PABPN1 readthrough

chr1_+_87797351 0.564 ENST00000370542.1
LMO4
LIM domain only 4
chrY_+_2803322 0.561 ENST00000383052.1
ENST00000155093.3
ENST00000449237.1
ENST00000443793.1
ZFY



zinc finger protein, Y-linked



chr6_-_52705641 0.560 ENST00000370989.2
GSTA5
glutathione S-transferase alpha 5
chr1_+_167190066 0.550 ENST00000367866.2
ENST00000429375.2
ENST00000452019.1
ENST00000420254.3
ENST00000541643.3
POU2F1




POU class 2 homeobox 1




chr10_+_114710211 0.548 ENST00000349937.2
ENST00000369397.4
TCF7L2

transcription factor 7-like 2 (T-cell specific, HMG-box)

chr13_-_86373536 0.544 ENST00000400286.2
SLITRK6
SLIT and NTRK-like family, member 6
chr8_+_28747884 0.542 ENST00000287701.10
ENST00000444075.1
ENST00000403668.2
ENST00000519662.1
ENST00000558662.1
ENST00000523613.1
ENST00000560599.1
ENST00000397358.3
HMBOX1







homeobox containing 1







chr11_-_46142948 0.541 ENST00000257821.4
PHF21A
PHD finger protein 21A
chr10_-_99094458 0.540 ENST00000371019.2
FRAT2
frequently rearranged in advanced T-cell lymphomas 2
chr2_+_189156586 0.539 ENST00000409830.1
GULP1
GULP, engulfment adaptor PTB domain containing 1
chr6_-_56112323 0.537 ENST00000535941.1
COL21A1
collagen, type XXI, alpha 1
chr9_-_80646374 0.529 ENST00000286548.4
GNAQ
guanine nucleotide binding protein (G protein), q polypeptide
chr3_+_69812701 0.525 ENST00000472437.1
MITF
microphthalmia-associated transcription factor
chr9_+_126773880 0.524 ENST00000373615.4
LHX2
LIM homeobox 2
chr19_-_49149553 0.521 ENST00000084798.4
CA11
carbonic anhydrase XI
chr6_-_99395787 0.518 ENST00000369244.2
ENST00000229971.1
FBXL4

F-box and leucine-rich repeat protein 4

chr11_-_9781068 0.516 ENST00000500698.1
RP11-540A21.2
RP11-540A21.2
chr4_-_185395672 0.513 ENST00000393593.3
IRF2
interferon regulatory factor 2
chr6_+_126112001 0.512 ENST00000392477.2
NCOA7
nuclear receptor coactivator 7
chr5_-_146833222 0.510 ENST00000534907.1
DPYSL3
dihydropyrimidinase-like 3
chr2_+_121103706 0.509 ENST00000295228.3
INHBB
inhibin, beta B
chr15_+_73344791 0.508 ENST00000261908.6
NEO1
neogenin 1
chr1_+_87794150 0.508 ENST00000370544.5
LMO4
LIM domain only 4
chr8_-_41909496 0.507 ENST00000265713.2
ENST00000406337.1
ENST00000396930.3
ENST00000485568.1
ENST00000426524.1
KAT6A




K(lysine) acetyltransferase 6A




chr2_+_189156389 0.507 ENST00000409843.1
GULP1
GULP, engulfment adaptor PTB domain containing 1
chr2_-_61697862 0.505 ENST00000398571.2
USP34
ubiquitin specific peptidase 34
chr17_-_49337392 0.504 ENST00000376381.2
ENST00000586178.1
MBTD1

mbt domain containing 1

chr14_+_93897272 0.504 ENST00000393151.2
UNC79
unc-79 homolog (C. elegans)
chr4_-_157892498 0.504 ENST00000502773.1
PDGFC
platelet derived growth factor C
chr17_-_42277203 0.502 ENST00000587097.1
ATXN7L3
ataxin 7-like 3
chr11_-_75380165 0.502 ENST00000304771.3
MAP6
microtubule-associated protein 6
chr11_+_65479702 0.502 ENST00000530446.1
ENST00000534104.1
ENST00000530605.1
ENST00000528198.1
ENST00000531880.1
ENST00000534650.1
KAT5





K(lysine) acetyltransferase 5





chr12_-_89918522 0.502 ENST00000529983.2
GALNT4
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 4 (GalNAc-T4)
chr1_+_164529004 0.501 ENST00000559240.1
ENST00000367897.1
ENST00000540236.1
ENST00000401534.1
PBX1



pre-B-cell leukemia homeobox 1



chr2_-_220110111 0.500 ENST00000428427.1
ENST00000356283.3
ENST00000432839.1
ENST00000424620.1
GLB1L



galactosidase, beta 1-like



chr2_-_220110187 0.497 ENST00000295759.7
ENST00000392089.2
GLB1L

galactosidase, beta 1-like

chr20_+_44098385 0.491 ENST00000217425.5
ENST00000339946.3
WFDC2

WAP four-disulfide core domain 2

chr9_-_3525968 0.490 ENST00000382004.3
ENST00000302303.1
ENST00000449190.1
RFX3


regulatory factor X, 3 (influences HLA class II expression)


chr14_-_76447494 0.489 ENST00000238682.3
TGFB3
transforming growth factor, beta 3
chr4_-_105416039 0.488 ENST00000394767.2
CXXC4
CXXC finger protein 4
chr7_+_69064300 0.484 ENST00000342771.4
AUTS2
autism susceptibility candidate 2
chr11_-_95522907 0.478 ENST00000358780.5
ENST00000542135.1
FAM76B

family with sequence similarity 76, member B

chr20_+_58179582 0.477 ENST00000371015.1
ENST00000395639.4
PHACTR3

phosphatase and actin regulator 3

chr6_+_41514078 0.474 ENST00000373063.3
ENST00000373060.1
FOXP4

forkhead box P4

chr2_-_148778323 0.474 ENST00000440042.1
ENST00000535373.1
ENST00000540442.1
ENST00000536575.1
ORC4



origin recognition complex, subunit 4



chr1_-_177133818 0.473 ENST00000424564.2
ENST00000361833.2
ASTN1

astrotactin 1

chr11_+_120894781 0.472 ENST00000529397.1
ENST00000528512.1
ENST00000422003.2
TBCEL


tubulin folding cofactor E-like


chr6_-_10838736 0.472 ENST00000536370.1
ENST00000474039.1
MAK

male germ cell-associated kinase

chr7_+_30951461 0.470 ENST00000311813.4
AQP1
aquaporin 1 (Colton blood group)
chr8_-_141467818 0.469 ENST00000389327.3
ENST00000438773.2
TRAPPC9

trafficking protein particle complex 9

chr12_-_104531785 0.465 ENST00000551727.1
NFYB
nuclear transcription factor Y, beta
chr1_+_156119466 0.464 ENST00000414683.1
SEMA4A
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr1_-_151299842 0.463 ENST00000438243.2
ENST00000489223.2
ENST00000368873.1
ENST00000430800.1
ENST00000368872.1
PI4KB




phosphatidylinositol 4-kinase, catalytic, beta




chr17_+_7155343 0.463 ENST00000573513.1
ENST00000354429.2
ENST00000574255.1
ENST00000396627.2
ENST00000356683.2
ELP5




elongator acetyltransferase complex subunit 5




chr8_+_37553261 0.461 ENST00000331569.4
ZNF703
zinc finger protein 703
chr6_-_32143828 0.455 ENST00000412465.2
ENST00000375107.3
AGPAT1

1-acylglycerol-3-phosphate O-acyltransferase 1

chr6_-_10838710 0.453 ENST00000313243.2
MAK
male germ cell-associated kinase
chr16_+_15528332 0.452 ENST00000566490.1
C16orf45
chromosome 16 open reading frame 45
chr12_-_104532062 0.452 ENST00000240055.3
NFYB
nuclear transcription factor Y, beta
chr5_+_139028510 0.451 ENST00000502336.1
ENST00000520967.1
ENST00000511048.1
CXXC5


CXXC finger protein 5


chr12_+_29302119 0.449 ENST00000536681.3
FAR2
fatty acyl CoA reductase 2
chr15_-_61521495 0.449 ENST00000335670.6
RORA
RAR-related orphan receptor A
chr12_-_81992111 0.447 ENST00000443686.3
ENST00000407050.4
PPFIA2

protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2

chr7_+_90893783 0.446 ENST00000287934.2
FZD1
frizzled family receptor 1
chr12_+_93772326 0.446 ENST00000550056.1
ENST00000549992.1
ENST00000548662.1
ENST00000547014.1
NUDT4



nudix (nucleoside diphosphate linked moiety X)-type motif 4



chr11_-_62474803 0.445 ENST00000533982.1
ENST00000360796.5
BSCL2

Berardinelli-Seip congenital lipodystrophy 2 (seipin)

chr11_+_76777979 0.443 ENST00000531028.1
ENST00000278559.3
ENST00000527066.1
ENST00000529629.1
CAPN5



calpain 5




Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.0 GO:0048389 intermediate mesoderm development(GO:0048389) pattern specification involved in mesonephros development(GO:0061227) anterior/posterior pattern specification involved in kidney development(GO:0072098)
0.6 3.3 GO:0010734 protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734)
0.5 1.6 GO:0072095 regulation of branch elongation involved in ureteric bud branching(GO:0072095)
0.5 1.9 GO:1900106 hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.4 1.7 GO:1902361 mitochondrial pyruvate transport(GO:0006850) mitochondrial pyruvate transmembrane transport(GO:1902361)
0.4 1.2 GO:0021919 BMP signaling pathway involved in spinal cord dorsal/ventral patterning(GO:0021919)
0.4 0.4 GO:0072053 renal inner medulla development(GO:0072053) renal outer medulla development(GO:0072054)
0.3 1.3 GO:0002503 peptide antigen assembly with MHC class II protein complex(GO:0002503)
0.3 1.2 GO:0010730 negative regulation of hydrogen peroxide biosynthetic process(GO:0010730)
0.3 0.6 GO:0061010 gall bladder development(GO:0061010)
0.3 1.1 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.3 6.2 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.3 2.0 GO:0071233 cellular response to leucine(GO:0071233)
0.3 0.8 GO:0038162 erythropoietin-mediated signaling pathway(GO:0038162)
0.2 1.2 GO:0060741 prostate gland stromal morphogenesis(GO:0060741) seminal vesicle development(GO:0061107)
0.2 0.9 GO:2000721 pilomotor reflex(GO:0097195) positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000721)
0.2 0.7 GO:0015817 acyl carnitine transport(GO:0006844) histidine transport(GO:0015817) L-histidine transmembrane transport(GO:0089709) L-histidine transport(GO:1902024) acyl carnitine transmembrane transport(GO:1902616)
0.2 1.4 GO:0003150 muscular septum morphogenesis(GO:0003150)
0.2 0.7 GO:0045925 positive regulation of female receptivity(GO:0045925)
0.2 0.8 GO:0090403 oxidative stress-induced premature senescence(GO:0090403)
0.2 2.7 GO:0048251 elastic fiber assembly(GO:0048251)
0.2 1.0 GO:0061031 endodermal digestive tract morphogenesis(GO:0061031)
0.2 0.6 GO:0050823 peptide stabilization(GO:0050822) peptide antigen stabilization(GO:0050823)
0.2 1.2 GO:0010908 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.2 0.2 GO:0090244 Wnt signaling pathway involved in somitogenesis(GO:0090244)
0.2 1.2 GO:0060011 Sertoli cell proliferation(GO:0060011)
0.2 1.2 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.2 0.7 GO:1901675 negative regulation of histone H3-K27 acetylation(GO:1901675)
0.2 0.5 GO:1904924 negative regulation of mitophagy in response to mitochondrial depolarization(GO:1904924)
0.2 0.3 GO:0097252 oligodendrocyte apoptotic process(GO:0097252)
0.2 0.5 GO:0002071 glandular epithelial cell maturation(GO:0002071) type B pancreatic cell maturation(GO:0072560)
0.2 1.6 GO:0097688 AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688)
0.2 0.5 GO:0072229 carbon dioxide transmembrane transport(GO:0035378) proximal convoluted tubule development(GO:0072019) metanephric proximal convoluted tubule development(GO:0072229)
0.2 0.6 GO:0010157 response to chlorate(GO:0010157)
0.1 0.4 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.1 1.0 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.1 0.4 GO:0021529 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.1 0.4 GO:0021823 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836)
0.1 2.0 GO:1903025 regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025)
0.1 0.4 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.1 0.7 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.1 0.9 GO:0033183 negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315)
0.1 0.4 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.1 0.4 GO:0035408 histone H3-T6 phosphorylation(GO:0035408)
0.1 0.5 GO:0097676 histone H3-K36 dimethylation(GO:0097676)
0.1 0.4 GO:0061188 negative regulation of chromatin silencing at rDNA(GO:0061188)
0.1 0.4 GO:2000276 negative regulation of oxidative phosphorylation uncoupler activity(GO:2000276)
0.1 1.0 GO:0070445 oligodendrocyte progenitor proliferation(GO:0070444) regulation of oligodendrocyte progenitor proliferation(GO:0070445)
0.1 0.8 GO:0051661 maintenance of centrosome location(GO:0051661)
0.1 0.7 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.1 0.4 GO:1990926 short-term synaptic potentiation(GO:1990926)
0.1 0.6 GO:0032474 otolith morphogenesis(GO:0032474) sensory system development(GO:0048880)
0.1 0.2 GO:0019230 proprioception(GO:0019230)
0.1 2.3 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.1 0.4 GO:1903422 negative regulation of synaptic vesicle recycling(GO:1903422)
0.1 0.7 GO:0060005 vestibular reflex(GO:0060005)
0.1 0.5 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.1 0.6 GO:1903281 protein transport into plasma membrane raft(GO:0044861) regulation of sodium ion export(GO:1903273) positive regulation of sodium ion export(GO:1903275) regulation of sodium ion export from cell(GO:1903276) positive regulation of sodium ion export from cell(GO:1903278) positive regulation of calcium:sodium antiporter activity(GO:1903281) positive regulation of potassium ion import(GO:1903288)
0.1 0.7 GO:1901908 diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.1 0.3 GO:0098582 innate vocalization behavior(GO:0098582)
0.1 0.7 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.1 0.9 GO:1902856 negative regulation of nonmotile primary cilium assembly(GO:1902856)
0.1 0.4 GO:1904844 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.1 0.3 GO:0093001 glycolysis from storage polysaccharide through glucose-1-phosphate(GO:0093001)
0.1 0.4 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.1 0.2 GO:1903279 regulation of calcium:sodium antiporter activity(GO:1903279)
0.1 0.4 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.1 1.3 GO:0042659 regulation of cell fate specification(GO:0042659)
0.1 0.4 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.1 1.2 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.1 0.7 GO:2001268 negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001268)
0.1 0.3 GO:2000820 negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000820)
0.1 0.8 GO:0070278 extracellular matrix constituent secretion(GO:0070278)
0.1 0.5 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.1 0.3 GO:0035621 ER to Golgi ceramide transport(GO:0035621)
0.1 0.4 GO:1903976 negative regulation of glial cell migration(GO:1903976)
0.1 0.3 GO:0001994 norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001994)
0.1 0.3 GO:0016103 diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653)
0.1 1.1 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.1 0.5 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.1 0.3 GO:0042986 positive regulation of amyloid precursor protein biosynthetic process(GO:0042986)
0.1 0.2 GO:0032289 central nervous system myelin formation(GO:0032289)
0.1 0.4 GO:0001714 endodermal cell fate specification(GO:0001714)
0.1 0.5 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.1 0.1 GO:2000291 regulation of myoblast proliferation(GO:2000291)
0.1 0.3 GO:0072658 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1 1.3 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.1 0.4 GO:0014005 microglia differentiation(GO:0014004) microglia development(GO:0014005)
0.1 0.5 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.1 0.4 GO:0010025 wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.1 0.4 GO:0051138 positive regulation of NK T cell differentiation(GO:0051138)
0.1 0.7 GO:0021759 globus pallidus development(GO:0021759)
0.1 0.1 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.1 0.3 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.1 0.4 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.1 0.3 GO:0021592 midbrain-hindbrain boundary morphogenesis(GO:0021555) fourth ventricle development(GO:0021592)
0.1 2.0 GO:0006337 nucleosome disassembly(GO:0006337)
0.1 0.2 GO:0042494 detection of bacterial lipoprotein(GO:0042494)
0.1 1.2 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.1 0.4 GO:1902659 regulation of glucose mediated signaling pathway(GO:1902659)
0.1 0.2 GO:0030860 regulation of polarized epithelial cell differentiation(GO:0030860)
0.1 0.4 GO:0015853 adenine transport(GO:0015853)
0.1 0.1 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.1 0.4 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.1 0.3 GO:0045872 positive regulation of rhodopsin gene expression(GO:0045872)
0.1 0.8 GO:2000580 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.1 0.3 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
0.1 0.3 GO:0032972 diaphragm contraction(GO:0002086) regulation of muscle filament sliding speed(GO:0032972)
0.1 0.2 GO:0003193 pulmonary valve formation(GO:0003193) regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652) foramen ovale closure(GO:0035922) regulation of bundle of His cell action potential(GO:0098905)
0.1 0.3 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.1 0.6 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.1 0.2 GO:0033385 geranylgeranyl diphosphate metabolic process(GO:0033385) geranylgeranyl diphosphate biosynthetic process(GO:0033386)
0.1 0.4 GO:0060355 positive regulation of cell adhesion molecule production(GO:0060355)
0.1 0.9 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.1 0.3 GO:0007290 spermatid nucleus elongation(GO:0007290)
0.1 0.2 GO:1904016 response to Thyroglobulin triiodothyronine(GO:1904016)
0.1 0.3 GO:0071350 interleukin-15-mediated signaling pathway(GO:0035723) cellular response to interleukin-15(GO:0071350)
0.1 0.1 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.1 1.2 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.1 0.4 GO:0033484 nitric oxide homeostasis(GO:0033484)
0.1 0.3 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
0.1 0.2 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.1 0.2 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314)
0.1 0.2 GO:1902303 negative regulation of potassium ion export(GO:1902303)
0.1 0.7 GO:1902260 negative regulation of delayed rectifier potassium channel activity(GO:1902260) negative regulation of voltage-gated potassium channel activity(GO:1903817)
0.1 2.3 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.1 0.4 GO:0030223 neutrophil differentiation(GO:0030223)
0.1 0.5 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.1 0.2 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.1 0.2 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.1 1.6 GO:0010669 epithelial structure maintenance(GO:0010669)
0.1 0.2 GO:0034125 negative regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034125)
0.1 0.2 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.1 0.2 GO:0006404 RNA import into nucleus(GO:0006404)
0.1 1.5 GO:0016578 histone deubiquitination(GO:0016578)
0.0 0.3 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
0.0 0.2 GO:0048496 maintenance of organ identity(GO:0048496)
0.0 0.2 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.0 0.3 GO:0043366 beta selection(GO:0043366)
0.0 0.3 GO:0070560 protein secretion by platelet(GO:0070560)
0.0 0.7 GO:0090360 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.0 1.0 GO:1904886 beta-catenin destruction complex disassembly(GO:1904886)
0.0 0.0 GO:0010159 specification of organ position(GO:0010159)
0.0 0.6 GO:0021694 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.0 0.0 GO:0008356 asymmetric cell division(GO:0008356)
0.0 0.4 GO:0010761 fibroblast migration(GO:0010761)
0.0 0.2 GO:0008584 male gonad development(GO:0008584) development of primary male sexual characteristics(GO:0046546) male sex differentiation(GO:0046661)
0.0 0.1 GO:0003032 detection of oxygen(GO:0003032) uterine wall breakdown(GO:0042704)
0.0 0.1 GO:1900186 negative regulation of clathrin-mediated endocytosis(GO:1900186) regulation of G-protein coupled receptor internalization(GO:1904020)
0.0 0.4 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.0 0.2 GO:0060023 soft palate development(GO:0060023)
0.0 0.3 GO:1990785 response to water-immersion restraint stress(GO:1990785)
0.0 0.1 GO:0072268 pattern specification involved in metanephros development(GO:0072268)
0.0 0.2 GO:0009386 translational attenuation(GO:0009386)
0.0 0.2 GO:0043335 protein unfolding(GO:0043335)
0.0 0.4 GO:0006526 arginine biosynthetic process(GO:0006526)
0.0 0.3 GO:0051106 positive regulation of DNA ligation(GO:0051106)
0.0 0.4 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.2 GO:0031017 exocrine pancreas development(GO:0031017)
0.0 0.2 GO:0050975 sensory perception of touch(GO:0050975)
0.0 0.3 GO:0035754 B cell chemotaxis(GO:0035754)
0.0 0.1 GO:0007412 axon target recognition(GO:0007412)
0.0 0.1 GO:0061197 fungiform papilla morphogenesis(GO:0061197)
0.0 0.2 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.0 0.5 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.1 GO:0032484 Ral protein signal transduction(GO:0032484) regulation of Ral protein signal transduction(GO:0032485)
0.0 0.0 GO:2000809 positive regulation of synaptic vesicle clustering(GO:2000809)
0.0 0.2 GO:0033563 dorsal/ventral axon guidance(GO:0033563)
0.0 0.1 GO:0070676 intralumenal vesicle formation(GO:0070676)
0.0 0.1 GO:0035544 negative regulation of SNARE complex assembly(GO:0035544)
0.0 0.2 GO:0090166 Golgi disassembly(GO:0090166)
0.0 0.9 GO:0032703 negative regulation of interleukin-2 production(GO:0032703)
0.0 0.3 GO:0072718 response to cisplatin(GO:0072718)
0.0 1.0 GO:0045063 T-helper 1 cell differentiation(GO:0045063)
0.0 0.4 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.0 0.5 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.8 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 2.7 GO:0007585 respiratory gaseous exchange(GO:0007585)
0.0 0.2 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079)
0.0 0.7 GO:0035563 positive regulation of chromatin binding(GO:0035563)
0.0 1.2 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.0 0.8 GO:0006744 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 0.6 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.0 0.1 GO:0035494 SNARE complex disassembly(GO:0035494)
0.0 0.1 GO:0019065 receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
0.0 0.1 GO:0097155 fasciculation of sensory neuron axon(GO:0097155)
0.0 0.2 GO:0015891 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.0 0.2 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.0 0.1 GO:0046013 T cell homeostatic proliferation(GO:0001777) regulation of T cell homeostatic proliferation(GO:0046013)
0.0 0.7 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.1 GO:1903659 regulation of complement-dependent cytotoxicity(GO:1903659)
0.0 0.1 GO:0019566 arabinose metabolic process(GO:0019566) L-arabinose metabolic process(GO:0046373)
0.0 0.2 GO:0032058 positive regulation of translational initiation in response to stress(GO:0032058)
0.0 0.3 GO:0070294 renal sodium ion transport(GO:0003096) renal sodium ion absorption(GO:0070294)
0.0 0.7 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.3 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.0 1.0 GO:0002244 hematopoietic progenitor cell differentiation(GO:0002244)
0.0 0.1 GO:0060431 primary lung bud formation(GO:0060431)
0.0 0.1 GO:0060964 regulation of gene silencing by miRNA(GO:0060964)
0.0 0.1 GO:0060633 negative regulation of transcription initiation from RNA polymerase II promoter(GO:0060633)
0.0 0.2 GO:0036438 maintenance of lens transparency(GO:0036438)
0.0 0.3 GO:0050910 detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.0 0.7 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.2 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 0.0 GO:0043974 histone H3-K27 acetylation(GO:0043974) regulation of histone H3-K27 acetylation(GO:1901674)
0.0 0.2 GO:0006983 ER overload response(GO:0006983)
0.0 0.2 GO:0060482 lobar bronchus development(GO:0060482)
0.0 1.6 GO:0042073 intraciliary transport(GO:0042073)
0.0 0.8 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.2 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.2 GO:0045924 regulation of female receptivity(GO:0045924)
0.0 0.1 GO:0021877 forebrain neuron fate commitment(GO:0021877) commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.0 0.1 GO:0071680 response to indole-3-methanol(GO:0071680) cellular response to indole-3-methanol(GO:0071681)
0.0 0.4 GO:0048681 negative regulation of axon regeneration(GO:0048681)
0.0 0.1 GO:0002904 positive regulation of B cell apoptotic process(GO:0002904)
0.0 0.4 GO:0044320 cellular response to leptin stimulus(GO:0044320)
0.0 0.4 GO:0042789 mRNA transcription from RNA polymerase II promoter(GO:0042789)
0.0 0.1 GO:2000821 regulation of grooming behavior(GO:2000821)
0.0 0.1 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.0 0.1 GO:0072369 regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369)
0.0 1.6 GO:0043966 histone H3 acetylation(GO:0043966)
0.0 0.1 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.0 0.2 GO:0009048 dosage compensation by inactivation of X chromosome(GO:0009048)
0.0 0.2 GO:0032355 response to estradiol(GO:0032355)
0.0 0.3 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0 0.2 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.1 GO:1903595 positive regulation of histamine secretion by mast cell(GO:1903595)
0.0 0.6 GO:0010971 positive regulation of G2/M transition of mitotic cell cycle(GO:0010971)
0.0 0.4 GO:2000678 negative regulation of transcription regulatory region DNA binding(GO:2000678)
0.0 1.7 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.2 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0 0.5 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.0 0.2 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.4 GO:1904380 endoplasmic reticulum mannose trimming(GO:1904380)
0.0 0.1 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
0.0 0.1 GO:0048865 ganglion mother cell fate determination(GO:0007402) stem cell fate commitment(GO:0048865) stem cell fate determination(GO:0048867)
0.0 0.1 GO:0015742 alpha-ketoglutarate transport(GO:0015742)
0.0 0.3 GO:0048298 positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.0 0.3 GO:0033235 positive regulation of protein sumoylation(GO:0033235)
0.0 0.1 GO:1903762 regulation of heart looping(GO:1901207) positive regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903762) positive regulation of ventricular cardiac muscle cell action potential(GO:1903947) positive regulation of membrane repolarization during ventricular cardiac muscle cell action potential(GO:1905026) positive regulation of membrane repolarization during cardiac muscle cell action potential(GO:1905033)
0.0 0.6 GO:0036150 phosphatidylserine acyl-chain remodeling(GO:0036150)
0.0 0.3 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.0 0.1 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.0 0.1 GO:0019072 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.0 0.3 GO:0008340 determination of adult lifespan(GO:0008340)
0.0 0.9 GO:0061014 positive regulation of mRNA catabolic process(GO:0061014)
0.0 1.7 GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.0 0.1 GO:0019240 citrulline biosynthetic process(GO:0019240)
0.0 0.2 GO:0003073 regulation of systemic arterial blood pressure(GO:0003073)
0.0 0.5 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 1.2 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 0.2 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.4 GO:0071420 cellular response to histamine(GO:0071420)
0.0 0.2 GO:0031086 nuclear-transcribed mRNA catabolic process, deadenylation-independent decay(GO:0031086) deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 0.1 GO:0006930 substrate-dependent cell migration, cell extension(GO:0006930)
0.0 0.1 GO:0048009 insulin-like growth factor receptor signaling pathway(GO:0048009)
0.0 0.1 GO:2000672 regulation of motor neuron apoptotic process(GO:2000671) negative regulation of motor neuron apoptotic process(GO:2000672)
0.0 0.4 GO:0043555 regulation of translation in response to stress(GO:0043555)
0.0 0.2 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.0 0.1 GO:0001889 liver development(GO:0001889) hepaticobiliary system development(GO:0061008)
0.0 0.2 GO:1990034 calcium ion export(GO:1901660) calcium ion export from cell(GO:1990034)
0.0 0.1 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.0 0.1 GO:0048050 post-embryonic eye morphogenesis(GO:0048050)
0.0 0.1 GO:0046341 CDP-diacylglycerol metabolic process(GO:0046341)
0.0 0.9 GO:2000144 positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0 2.7 GO:0030449 regulation of complement activation(GO:0030449)
0.0 1.7 GO:0016575 histone deacetylation(GO:0016575)
0.0 0.1 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0 0.6 GO:0045724 positive regulation of cilium assembly(GO:0045724)
0.0 0.1 GO:0031937 positive regulation of chromatin silencing(GO:0031937)
0.0 0.2 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.0 0.1 GO:0050758 thymidylate synthase biosynthetic process(GO:0050757) regulation of thymidylate synthase biosynthetic process(GO:0050758) cellular response to folic acid(GO:0071231)
0.0 0.1 GO:0016479 negative regulation of transcription from RNA polymerase I promoter(GO:0016479) negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901837)
0.0 0.4 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.0 0.4 GO:0034389 lipid particle organization(GO:0034389)
0.0 0.1 GO:0033601 positive regulation of mammary gland epithelial cell proliferation(GO:0033601)
0.0 0.2 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.1 GO:0060154 cellular process regulating host cell cycle in response to virus(GO:0060154)
0.0 0.2 GO:0021999 neural plate anterior/posterior regionalization(GO:0021999)
0.0 0.1 GO:0032877 positive regulation of DNA endoreduplication(GO:0032877) negative regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071930)
0.0 0.1 GO:0033490 cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490)
0.0 0.3 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.0 0.0 GO:0010643 cell communication by chemical coupling(GO:0010643)
0.0 0.6 GO:0046329 negative regulation of JNK cascade(GO:0046329)
0.0 0.2 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 0.1 GO:0060965 negative regulation of gene silencing by miRNA(GO:0060965)
0.0 0.8 GO:0008542 visual learning(GO:0008542)
0.0 0.1 GO:1902514 regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1902514)
0.0 0.0 GO:1902299 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.0 0.2 GO:0035246 peptidyl-arginine N-methylation(GO:0035246)
0.0 0.3 GO:0043403 skeletal muscle tissue regeneration(GO:0043403)
0.0 0.2 GO:1900025 negative regulation of substrate adhesion-dependent cell spreading(GO:1900025)
0.0 0.1 GO:0032264 IMP salvage(GO:0032264)
0.0 0.2 GO:0031069 hair follicle morphogenesis(GO:0031069)
0.0 0.2 GO:0048149 behavioral response to ethanol(GO:0048149)
0.0 0.1 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.7 GO:0070534 protein K63-linked ubiquitination(GO:0070534)
0.0 0.0 GO:0038193 thromboxane A2 signaling pathway(GO:0038193)
0.0 0.1 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.0 0.4 GO:0030828 positive regulation of cGMP biosynthetic process(GO:0030828)
0.0 0.1 GO:0042373 vitamin K metabolic process(GO:0042373)
0.0 0.1 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.0 0.1 GO:0043633 polyadenylation-dependent RNA catabolic process(GO:0043633) polyadenylation-dependent ncRNA catabolic process(GO:0043634)
0.0 0.5 GO:1901685 glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
0.0 0.0 GO:1902804 negative regulation of synaptic vesicle transport(GO:1902804)
0.0 0.2 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.1 GO:0044827 modulation by host of viral genome replication(GO:0044827)
0.0 0.1 GO:0060399 positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.0 0.1 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.0 0.1 GO:0045900 negative regulation of translational elongation(GO:0045900)
0.0 0.1 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.0 0.1 GO:0019317 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.0 0.1 GO:1903756 positive regulation of dendritic spine maintenance(GO:1902952) regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
0.0 0.2 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.0 0.1 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.0 0.2 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.0 0.0 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.1 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.0 0.2 GO:1904714 chaperone-mediated autophagy(GO:0061684) regulation of chaperone-mediated autophagy(GO:1904714)
0.0 1.3 GO:0006911 phagocytosis, engulfment(GO:0006911)
0.0 0.5 GO:0007520 myoblast fusion(GO:0007520)
0.0 0.2 GO:0000768 syncytium formation by plasma membrane fusion(GO:0000768)
0.0 0.6 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.1 GO:0018195 peptidyl-arginine modification(GO:0018195)
0.0 0.0 GO:1901656 glycoside transport(GO:1901656)
0.0 0.0 GO:0048075 positive regulation of eye pigmentation(GO:0048075)
0.0 0.1 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.1 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.0 0.1 GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling(GO:0014068)
0.0 0.2 GO:0070314 G1 to G0 transition(GO:0070314)
0.0 0.1 GO:0045657 apoptotic chromosome condensation(GO:0030263) positive regulation of monocyte differentiation(GO:0045657)
0.0 0.3 GO:0031103 axon regeneration(GO:0031103)
0.0 0.0 GO:0044111 development involved in symbiotic interaction(GO:0044111)
0.0 0.3 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)
0.0 0.1 GO:0001554 luteolysis(GO:0001554)
0.0 0.2 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.0 0.1 GO:0017145 stem cell division(GO:0017145)
0.0 0.1 GO:0006540 glutamate decarboxylation to succinate(GO:0006540)
0.0 0.1 GO:0043922 negative regulation by host of viral transcription(GO:0043922)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 4.7 GO:0071953 elastic fiber(GO:0071953)
0.4 2.5 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.3 2.0 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.3 1.0 GO:0072534 perineuronal net(GO:0072534)
0.3 1.6 GO:0002079 inner acrosomal membrane(GO:0002079)
0.3 1.1 GO:0005667 transcription factor complex(GO:0005667)
0.2 1.2 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.2 1.1 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.2 0.5 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.2 4.0 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.2 0.8 GO:0034678 integrin alpha8-beta1 complex(GO:0034678)
0.2 0.5 GO:0020005 symbiont-containing vacuole(GO:0020003) symbiont-containing vacuole membrane(GO:0020005)
0.1 2.4 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.1 1.5 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.1 0.1 GO:1990923 PET complex(GO:1990923)
0.1 1.4 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.1 0.1 GO:0044292 dendrite terminus(GO:0044292)
0.1 1.6 GO:0000124 SAGA complex(GO:0000124)
0.1 1.4 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.1 0.3 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.1 0.6 GO:0042825 TAP complex(GO:0042825)
0.1 0.3 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.1 0.8 GO:0001739 sex chromatin(GO:0001739)
0.1 0.6 GO:0044294 dendritic growth cone(GO:0044294)
0.1 0.2 GO:0048179 activin receptor complex(GO:0048179)
0.1 0.5 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.1 0.7 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.1 1.3 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 0.2 GO:1990851 Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.1 0.2 GO:0036398 TCR signalosome(GO:0036398)
0.1 0.2 GO:0030289 protein phosphatase 4 complex(GO:0030289)
0.1 0.8 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.1 3.7 GO:1990391 DNA repair complex(GO:1990391)
0.1 0.9 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.1 0.3 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.1 1.9 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.1 0.2 GO:0060187 cell pole(GO:0060187)
0.1 0.4 GO:0000835 ER ubiquitin ligase complex(GO:0000835)
0.0 1.6 GO:0031304 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.8 GO:0033391 chromatoid body(GO:0033391)
0.0 0.2 GO:0031673 H zone(GO:0031673)
0.0 0.3 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0 0.3 GO:1990584 cardiac Troponin complex(GO:1990584)
0.0 1.0 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.2 GO:0089717 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.0 1.7 GO:0090544 BAF-type complex(GO:0090544)
0.0 0.1 GO:0031933 telomeric heterochromatin(GO:0031933)
0.0 0.4 GO:1990111 spermatoproteasome complex(GO:1990111)
0.0 0.2 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.0 0.4 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0 0.2 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.4 GO:0000439 core TFIIH complex(GO:0000439)
0.0 0.1 GO:0061574 ASAP complex(GO:0061574)
0.0 0.3 GO:0000235 astral microtubule(GO:0000235) aster(GO:0005818)
0.0 0.2 GO:0042584 chromaffin granule membrane(GO:0042584)
0.0 1.0 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.2 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.0 0.7 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.3 GO:0032009 early phagosome(GO:0032009)
0.0 0.2 GO:0034464 BBSome(GO:0034464)
0.0 1.4 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.1 GO:0070288 intracellular ferritin complex(GO:0008043) ferritin complex(GO:0070288)
0.0 0.5 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.4 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 0.9 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.8 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 0.1 GO:0031501 mannosyltransferase complex(GO:0031501)
0.0 0.1 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.3 GO:0042788 polysomal ribosome(GO:0042788)
0.0 1.0 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.2 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204) GAIT complex(GO:0097452)
0.0 0.6 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.1 GO:0030891 VCB complex(GO:0030891)
0.0 0.2 GO:1990909 Wnt signalosome(GO:1990909)
0.0 0.8 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.2 GO:0014802 terminal cisterna(GO:0014802)
0.0 0.6 GO:0044453 nuclear membrane part(GO:0044453)
0.0 0.4 GO:0005844 polysome(GO:0005844)
0.0 0.8 GO:0042629 mast cell granule(GO:0042629)
0.0 0.8 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 2.1 GO:0036064 ciliary basal body(GO:0036064)
0.0 0.2 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.0 2.2 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.1 GO:0016600 flotillin complex(GO:0016600)
0.0 1.1 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.5 GO:0034706 sodium channel complex(GO:0034706)
0.0 0.6 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 1.2 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 0.5 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.2 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 1.6 GO:0035577 azurophil granule membrane(GO:0035577)
0.0 0.2 GO:0001741 XY body(GO:0001741)
0.0 0.8 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.1 GO:0005827 polar microtubule(GO:0005827)
0.0 0.4 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.2 GO:0000306 extrinsic component of vacuolar membrane(GO:0000306)
0.0 0.6 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.1 GO:0008537 proteasome activator complex(GO:0008537)
0.0 0.1 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.0 0.3 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.0 0.4 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.4 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 0.8 GO:0000786 nucleosome(GO:0000786)
0.0 0.2 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 1.2 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.2 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 2.0 GO:0031902 late endosome membrane(GO:0031902)
0.0 0.1 GO:0097427 microtubule bundle(GO:0097427)
0.0 0.1 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.4 GO:0045259 proton-transporting ATP synthase complex(GO:0045259)
0.0 0.3 GO:0071004 U2-type prespliceosome(GO:0071004)
0.0 0.5 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.1 GO:1990393 3M complex(GO:1990393)
0.0 1.8 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 1.4 GO:0005581 collagen trimer(GO:0005581)
0.0 0.5 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.3 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.1 GO:0097227 sperm annulus(GO:0097227)
0.0 0.1 GO:0032039 integrator complex(GO:0032039)
0.0 0.1 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.7 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.5 1.6 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.3 1.6 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.3 3.4 GO:0070700 BMP receptor binding(GO:0070700)
0.3 2.9 GO:0034056 estrogen response element binding(GO:0034056)
0.2 1.0 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.2 1.6 GO:0004522 ribonuclease A activity(GO:0004522)
0.2 0.7 GO:0015227 acyl carnitine transmembrane transporter activity(GO:0015227)
0.2 6.1 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.2 0.7 GO:0052810 1-phosphatidylinositol-5-kinase activity(GO:0052810)
0.2 1.7 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.2 0.5 GO:0035034 histone acetyltransferase regulator activity(GO:0035034)
0.2 1.2 GO:0050682 AF-2 domain binding(GO:0050682)
0.2 0.5 GO:0035379 carbon dioxide transmembrane transporter activity(GO:0035379)
0.1 0.6 GO:0036033 mediator complex binding(GO:0036033)
0.1 0.5 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.1 0.4 GO:0035403 histone kinase activity (H3-T6 specific)(GO:0035403)
0.1 1.2 GO:0045545 syndecan binding(GO:0045545)
0.1 0.7 GO:0019828 aspartic-type endopeptidase inhibitor activity(GO:0019828)
0.1 0.6 GO:0015433 peptide antigen-transporting ATPase activity(GO:0015433)
0.1 1.2 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.1 0.7 GO:0000298 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848)
0.1 0.4 GO:0005471 ATP:ADP antiporter activity(GO:0005471) adenine transmembrane transporter activity(GO:0015207)
0.1 0.3 GO:0003863 alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863)
0.1 0.6 GO:0016520 growth hormone-releasing hormone receptor activity(GO:0016520)
0.1 0.6 GO:0045118 azole transporter activity(GO:0045118)
0.1 0.3 GO:0047223 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity(GO:0047223)
0.1 1.4 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.1 0.3 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.1 0.6 GO:0005119 smoothened binding(GO:0005119)
0.1 1.0 GO:0004565 beta-galactosidase activity(GO:0004565)
0.1 0.9 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.1 1.1 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.1 0.8 GO:0008142 oxysterol binding(GO:0008142)
0.1 1.2 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087) TFIIB-class transcription factor binding(GO:0001093)
0.1 0.4 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.1 0.5 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.1 0.3 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.1 0.3 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.1 0.8 GO:0048039 ubiquinone binding(GO:0048039)
0.1 0.7 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.1 3.8 GO:0070888 E-box binding(GO:0070888)
0.1 0.8 GO:0030274 LIM domain binding(GO:0030274)
0.1 0.3 GO:0042289 MHC class II protein binding(GO:0042289)
0.1 0.1 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.1 0.4 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.1 0.9 GO:0003964 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.1 0.3 GO:0031849 olfactory receptor binding(GO:0031849)
0.1 0.4 GO:0043532 angiostatin binding(GO:0043532)
0.1 0.4 GO:0030197 extracellular matrix constituent, lubricant activity(GO:0030197)
0.1 0.4 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.1 0.4 GO:0097001 ceramide binding(GO:0097001)
0.1 0.3 GO:0097100 supercoiled DNA binding(GO:0097100)
0.1 2.1 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.1 0.5 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.1 0.3 GO:0060422 peptidyl-dipeptidase inhibitor activity(GO:0060422)
0.1 0.1 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.1 1.4 GO:0051400 BH domain binding(GO:0051400)
0.1 1.2 GO:0045295 gamma-catenin binding(GO:0045295)
0.1 1.0 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.1 1.3 GO:0038191 neuropilin binding(GO:0038191)
0.1 0.2 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.1 0.3 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.1 0.2 GO:0031751 D4 dopamine receptor binding(GO:0031751)
0.1 0.2 GO:0070051 fibrinogen binding(GO:0070051)
0.1 0.3 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.1 0.5 GO:0039706 co-receptor binding(GO:0039706)
0.1 0.2 GO:0001602 pancreatic polypeptide receptor activity(GO:0001602)
0.1 4.2 GO:0004407 histone deacetylase activity(GO:0004407)
0.1 0.2 GO:0098640 integrin binding involved in cell-matrix adhesion(GO:0098640)
0.1 0.3 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.1 0.9 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.1 0.4 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.0 1.4 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.0 0.7 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.0 0.8 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.2 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0 0.2 GO:0035939 microsatellite binding(GO:0035939)
0.0 0.2 GO:0030337 DNA polymerase processivity factor activity(GO:0030337)
0.0 1.1 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.6 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.0 0.3 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.0 0.0 GO:0051022 GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022)
0.0 0.2 GO:0004376 glycolipid mannosyltransferase activity(GO:0004376)
0.0 3.4 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.2 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.5 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.2 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.6 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.2 GO:0032184 SUMO polymer binding(GO:0032184)
0.0 0.5 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.0 0.1 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 1.1 GO:0030275 LRR domain binding(GO:0030275)
0.0 0.8 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.4 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.2 GO:0004337 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.0 2.5 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 1.0 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.1 GO:0004019 adenylosuccinate synthase activity(GO:0004019)
0.0 0.4 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.2 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.0 1.3 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.2 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095)
0.0 4.8 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 0.5 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.0 0.2 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.0 0.1 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.0 0.2 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 0.4 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.2 GO:0016361 activin receptor activity, type I(GO:0016361)
0.0 0.1 GO:0046556 alpha-L-arabinofuranosidase activity(GO:0046556)
0.0 0.6 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.4 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.5 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 0.1 GO:0005275 amine transmembrane transporter activity(GO:0005275)
0.0 0.1 GO:0047057 oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
0.0 1.2 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.1 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.0 0.2 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.1 GO:0015616 DNA translocase activity(GO:0015616)
0.0 0.2 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.0 1.0 GO:0034061 DNA-directed DNA polymerase activity(GO:0003887) DNA polymerase activity(GO:0034061)
0.0 0.3 GO:0003910 DNA ligase (ATP) activity(GO:0003910)
0.0 0.2 GO:0017018 myosin phosphatase activity(GO:0017018)
0.0 0.2 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 0.2 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.0 GO:0038049 transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049)
0.0 0.2 GO:0003998 acylphosphatase activity(GO:0003998)
0.0 0.1 GO:0015140 malate transmembrane transporter activity(GO:0015140)
0.0 0.7 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.2 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0 0.1 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.0 0.4 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.2 GO:0036132 13-prostaglandin reductase activity(GO:0036132) 15-oxoprostaglandin 13-oxidase activity(GO:0047522)
0.0 0.1 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0 0.3 GO:0031013 troponin I binding(GO:0031013)
0.0 0.4 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.3 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.4 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.0 0.3 GO:0015377 cation:chloride symporter activity(GO:0015377)
0.0 0.3 GO:0004017 adenylate kinase activity(GO:0004017)
0.0 0.2 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 1.8 GO:0019003 GDP binding(GO:0019003)
0.0 0.6 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.2 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.1 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.1 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.0 0.3 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 1.6 GO:0043621 protein self-association(GO:0043621)
0.0 0.3 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 1.1 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 0.6 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.0 2.0 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 1.2 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.2 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.1 GO:0003881 CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity(GO:0003881)
0.0 0.6 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 0.1 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
0.0 0.0 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
0.0 0.1 GO:0061714 folic acid receptor activity(GO:0061714)
0.0 1.0 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.1 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.2 GO:0015217 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.0 0.2 GO:0019534 toxin transporter activity(GO:0019534)
0.0 0.9 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.2 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.2 GO:0016273 arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
0.0 0.1 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.0 0.4 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.1 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.4 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.4 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 0.4 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.1 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0 0.2 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.1 GO:0042296 ISG15 transferase activity(GO:0042296)
0.0 0.1 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 0.0 GO:0004961 thromboxane receptor activity(GO:0004960) thromboxane A2 receptor activity(GO:0004961)
0.0 0.2 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.2 GO:0031402 sodium ion binding(GO:0031402)
0.0 0.0 GO:1904929 coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.0 0.1 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.2 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.1 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.0 0.3 GO:0035198 miRNA binding(GO:0035198)
0.0 0.1 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.0 0.3 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 0.1 GO:0003847 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.0 0.2 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.0 GO:0015275 stretch-activated, cation-selective, calcium channel activity(GO:0015275)
0.0 0.2 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.6 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 1.1 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.1 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.0 0.2 GO:0038132 neuregulin binding(GO:0038132)
0.0 0.1 GO:0034511 U3 snoRNA binding(GO:0034511)
0.0 0.7 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 0.2 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0 0.4 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.1 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.0 0.0 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.0 0.3 GO:0070300 phosphatidic acid binding(GO:0070300)
0.0 0.0 GO:0070698 type I activin receptor binding(GO:0070698)
0.0 0.1 GO:0030348 syntaxin-3 binding(GO:0030348)
0.0 0.2 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.0 0.3 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 0.0 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.5 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.0 GO:0051748 UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
0.0 0.2 GO:0070410 co-SMAD binding(GO:0070410)
0.0 0.3 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.1 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 ST_G_ALPHA_I_PATHWAY G alpha i Pathway
0.1 1.8 PID_ALK2_PATHWAY ALK2 signaling events
0.1 5.6 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.1 1.4 ST_STAT3_PATHWAY STAT3 Pathway
0.1 2.7 ST_MYOCYTE_AD_PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.1 1.9 ST_WNT_CA2_CYCLIC_GMP_PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.1 0.3 SIG_BCR_SIGNALING_PATHWAY Members of the BCR signaling pathway
0.1 0.4 PID_AVB3_INTEGRIN_PATHWAY Integrins in angiogenesis
0.0 1.1 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.6 PID_WNT_CANONICAL_PATHWAY Canonical Wnt signaling pathway
0.0 0.8 PID_CIRCADIAN_PATHWAY Circadian rhythm pathway
0.0 2.0 PID_IL6_7_PATHWAY IL6-mediated signaling events
0.0 0.2 PID_HDAC_CLASSII_PATHWAY Signaling events mediated by HDAC Class II
0.0 3.0 PID_AR_PATHWAY Coregulation of Androgen receptor activity
0.0 0.6 PID_ERB_GENOMIC_PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.6 PID_TCR_JNK_PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 1.3 PID_HEDGEHOG_GLI_PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.3 PID_P38_GAMMA_DELTA_PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.7 PID_AVB3_OPN_PATHWAY Osteopontin-mediated events
0.0 0.7 PID_MAPK_TRK_PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 2.3 PID_MYC_REPRESS_PATHWAY Validated targets of C-MYC transcriptional repression
0.0 1.7 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.0 0.2 PID_ANGIOPOIETIN_RECEPTOR_PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.9 PID_WNT_NONCANONICAL_PATHWAY Noncanonical Wnt signaling pathway
0.0 1.1 PID_ARF6_PATHWAY Arf6 signaling events
0.0 0.6 PID_HDAC_CLASSIII_PATHWAY Signaling events mediated by HDAC Class III
0.0 1.0 PID_BMP_PATHWAY BMP receptor signaling
0.0 0.8 PID_PS1_PATHWAY Presenilin action in Notch and Wnt signaling
0.0 0.5 PID_EPO_PATHWAY EPO signaling pathway
0.0 0.9 PID_ERA_GENOMIC_PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.1 PID_IL3_PATHWAY IL3-mediated signaling events
0.0 0.3 PID_A6B1_A6B4_INTEGRIN_PATHWAY a6b1 and a6b4 Integrin signaling
0.0 0.3 PID_RB_1PATHWAY Regulation of retinoblastoma protein
0.0 0.4 PID_EPHB_FWD_PATHWAY EPHB forward signaling
0.0 1.1 PID_REG_GR_PATHWAY Glucocorticoid receptor regulatory network
0.0 0.6 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.2 PID_KIT_PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.2 PID_ARF_3PATHWAY Arf1 pathway
0.0 3.1 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.2 PID_ARF6_DOWNSTREAM_PATHWAY Arf6 downstream pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_ATF6_ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1 2.1 REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.1 2.7 REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.1 0.3 REACTOME_BINDING_AND_ENTRY_OF_HIV_VIRION Genes involved in Binding and entry of HIV virion
0.1 1.1 REACTOME_IL_6_SIGNALING Genes involved in Interleukin-6 signaling
0.1 0.8 REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS Genes involved in Regulation of gene expression in beta cells
0.1 0.8 REACTOME_CDC6_ASSOCIATION_WITH_THE_ORC_ORIGIN_COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.1 1.0 REACTOME_ERK_MAPK_TARGETS Genes involved in ERK/MAPK targets
0.0 1.2 REACTOME_OTHER_SEMAPHORIN_INTERACTIONS Genes involved in Other semaphorin interactions
0.0 1.3 REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 2.2 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.0 0.9 REACTOME_CTNNB1_PHOSPHORYLATION_CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.7 REACTOME_ACYL_CHAIN_REMODELLING_OF_PS Genes involved in Acyl chain remodelling of PS
0.0 0.3 REACTOME_APOBEC3G_MEDIATED_RESISTANCE_TO_HIV1_INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.6 REACTOME_SIGNAL_ATTENUATION Genes involved in Signal attenuation
0.0 0.4 REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_24_HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 1.1 REACTOME_RNA_POL_I_TRANSCRIPTION_INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.0 0.5 REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.3 REACTOME_DOPAMINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.0 0.7 REACTOME_REGULATION_OF_KIT_SIGNALING Genes involved in Regulation of KIT signaling
0.0 0.8 REACTOME_BOTULINUM_NEUROTOXICITY Genes involved in Botulinum neurotoxicity
0.0 0.5 REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 1.4 REACTOME_RNA_POL_III_TRANSCRIPTION Genes involved in RNA Polymerase III Transcription
0.0 1.1 REACTOME_GLUTATHIONE_CONJUGATION Genes involved in Glutathione conjugation
0.0 0.6 REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.4 REACTOME_RETROGRADE_NEUROTROPHIN_SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.2 REACTOME_ACTIVATION_OF_THE_AP1_FAMILY_OF_TRANSCRIPTION_FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.5 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_GOLGI_MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.4 REACTOME_ACTIVATION_OF_BH3_ONLY_PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.6 REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.5 REACTOME_ADP_SIGNALLING_THROUGH_P2RY1 Genes involved in ADP signalling through P2Y purinoceptor 1
0.0 0.1 REACTOME_REGULATION_OF_HYPOXIA_INDUCIBLE_FACTOR_HIF_BY_OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0 0.0 REACTOME_NEP_NS2_INTERACTS_WITH_THE_CELLULAR_EXPORT_MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0 0.5 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_PLASMA_MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.4 REACTOME_PEROXISOMAL_LIPID_METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 1.2 REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.5 REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.4 REACTOME_SIGNALING_BY_HIPPO Genes involved in Signaling by Hippo
0.0 0.4 REACTOME_CYTOSOLIC_SULFONATION_OF_SMALL_MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.2 REACTOME_HIGHLY_CALCIUM_PERMEABLE_POSTSYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.0 0.4 REACTOME_SYNTHESIS_OF_PC Genes involved in Synthesis of PC
0.0 0.5 REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.8 REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.3 REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.6 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.2 REACTOME_LYSOSOME_VESICLE_BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.2 REACTOME_SIGNALING_BY_NODAL Genes involved in Signaling by NODAL