Motif ID: GUAGUGU

Z-value: 0.313


Mature miRNA associated with seed GUAGUGU:

NamemiRBase Accession
hsa-miR-142-3p.1 MIMAT0000434



Activity profile for motif GUAGUGU.

activity profile for motif GUAGUGU


Sorted Z-values histogram for motif GUAGUGU

Sorted Z-values for motif GUAGUGU



Network of associatons between targets according to the STRING database.



First level regulatory network of GUAGUGU

PNG image of the network

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Top targets:


Showing 1 to 20 of 186 entries
PromoterScoreRefseqGene SymbolGene Name
chr21_-_44846999 0.313 ENST00000270162.6
SIK1
salt-inducible kinase 1
chr4_-_139163491 0.253 ENST00000280612.5
SLC7A11
solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
chrX_+_44732757 0.209 ENST00000377967.4
ENST00000536777.1
ENST00000382899.4
ENST00000543216.1
KDM6A



lysine (K)-specific demethylase 6A



chr1_+_25071848 0.205 ENST00000374379.4
CLIC4
chloride intracellular channel 4
chr4_+_113066552 0.183 ENST00000309733.5
C4orf32
chromosome 4 open reading frame 32
chr1_+_218519577 0.163 ENST00000366930.4
ENST00000366929.4
TGFB2

transforming growth factor, beta 2

chr12_+_66217911 0.161 ENST00000403681.2
HMGA2
high mobility group AT-hook 2
chr17_-_4806369 0.158 ENST00000293780.4
CHRNE
cholinergic receptor, nicotinic, epsilon (muscle)
chr11_+_102188272 0.141 ENST00000532808.1
BIRC3
baculoviral IAP repeat containing 3
chr19_+_16187085 0.140 ENST00000300933.4
TPM4
tropomyosin 4
chr11_+_13299186 0.133 ENST00000527998.1
ENST00000396441.3
ENST00000533520.1
ENST00000529825.1
ENST00000389707.4
ENST00000401424.1
ENST00000529388.1
ENST00000530357.1
ENST00000403290.1
ENST00000361003.4
ENST00000389708.3
ENST00000403510.3
ENST00000482049.1
ARNTL












aryl hydrocarbon receptor nuclear translocator-like












chr3_+_152552685 0.132 ENST00000305097.3
P2RY1
purinergic receptor P2Y, G-protein coupled, 1
chr14_-_31676964 0.128 ENST00000553700.1
HECTD1
HECT domain containing E3 ubiquitin protein ligase 1
chr10_-_61666267 0.125 ENST00000263102.6
CCDC6
coiled-coil domain containing 6
chr19_-_15560730 0.122 ENST00000389282.4
ENST00000263381.7
WIZ

widely interspaced zinc finger motifs

chrX_-_41782249 0.122 ENST00000442742.2
ENST00000421587.2
ENST00000378166.4
ENST00000318588.9
ENST00000361962.4
CASK




calcium/calmodulin-dependent serine protein kinase (MAGUK family)




chr5_+_95066823 0.117 ENST00000506817.1
ENST00000379982.3
RHOBTB3

Rho-related BTB domain containing 3

chrX_+_70316005 0.111 ENST00000374259.3
FOXO4
forkhead box O4
chr7_-_20826504 0.110 ENST00000418710.2
ENST00000361443.4
SP8

Sp8 transcription factor

chr7_+_20370746 0.107 ENST00000222573.4
ITGB8
integrin, beta 8

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 24 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 0.3 GO:0032792 negative regulation of CREB transcription factor activity(GO:0032792)
0.1 0.2 GO:0051795 positive regulation of catagen(GO:0051795)
0.1 0.2 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.0 0.2 GO:0031052 mesodermal-endodermal cell signaling(GO:0003131) programmed DNA elimination(GO:0031049) chromosome breakage(GO:0031052) histone H2A-S139 phosphorylation(GO:0035978) positive regulation of cellular response to X-ray(GO:2000685)
0.0 0.2 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.0 0.1 GO:0060279 regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.0 0.1 GO:0090403 oxidative stress-induced premature senescence(GO:0090403)
0.0 0.1 GO:1903526 negative regulation of membrane tubulation(GO:1903526)
0.0 0.1 GO:0060406 positive regulation of penile erection(GO:0060406)
0.0 0.1 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.0 0.1 GO:0032252 secretory granule localization(GO:0032252)
0.0 0.1 GO:1900248 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
0.0 0.1 GO:1990785 negative regulation of G0 to G1 transition(GO:0070317) response to water-immersion restraint stress(GO:1990785)
0.0 0.1 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.0 0.1 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.0 0.1 GO:0061763 multivesicular body-lysosome fusion(GO:0061763)
0.0 0.1 GO:0070424 regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070424)
0.0 0.1 GO:0030047 actin modification(GO:0030047)
0.0 0.1 GO:1903923 protein processing in phagocytic vesicle(GO:1900756) regulation of protein processing in phagocytic vesicle(GO:1903921) positive regulation of protein processing in phagocytic vesicle(GO:1903923)
0.0 0.1 GO:0061737 leukotriene signaling pathway(GO:0061737)

Gene overrepresentation in cellular_component category:

Showing 1 to 8 of 8 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.2 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.2 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.0 0.1 GO:0034686 integrin alphav-beta8 complex(GO:0034686)
0.0 0.1 GO:0043511 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.0 0.1 GO:0001674 female germ cell nucleus(GO:0001674)
0.0 0.1 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.0 0.1 GO:0005826 actomyosin contractile ring(GO:0005826)
0.0 0.0 GO:0033565 ESCRT-0 complex(GO:0033565)

Gene overrepresentation in molecular_function category:

Showing 1 to 11 of 11 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 0.3 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.0 0.3 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 0.2 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0 0.2 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.0 0.2 GO:0035501 MH1 domain binding(GO:0035501)
0.0 0.1 GO:0070984 SET domain binding(GO:0070984)
0.0 0.1 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 0.1 GO:0031685 adenosine receptor binding(GO:0031685)
0.0 0.1 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.0 0.1 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.0 0.1 GO:0004974 leukotriene receptor activity(GO:0004974)