Motif ID: GZF1

Z-value: 0.344


Transcription factors associated with GZF1:

Gene SymbolEntrez IDGene Name
GZF1 ENSG00000125812.11 GZF1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
GZF1hg19_v2_chr20_+_23342783_233429570.405.6e-02Click!


Activity profile for motif GZF1.

activity profile for motif GZF1


Sorted Z-values histogram for motif GZF1

Sorted Z-values for motif GZF1



Network of associatons between targets according to the STRING database.



First level regulatory network of GZF1

PNG image of the network

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Top targets:


Showing 1 to 20 of 55 entries
PromoterScoreRefseqGene SymbolGene Name
chr11_+_101918153 1.373 ENST00000434758.2
ENST00000526781.1
ENST00000534360.1
 C11orf70


chromosome 11 open reading frame 70


chr1_+_79115503 0.637 ENST00000370747.4
ENST00000438486.1
ENST00000545124.1
 IFI44


interferon-induced protein 44


chr9_-_124976185 0.556 ENST00000464484.2
 LHX6
LIM homeobox 6
chr9_-_124976154 0.556 ENST00000482062.1
 LHX6
LIM homeobox 6
chr20_+_42086525 0.551 ENST00000244020.3
 SRSF6
serine/arginine-rich splicing factor 6
chr12_+_104458235 0.498 ENST00000229330.4
 HCFC2
host cell factor C2
chr14_-_92413727 0.458 ENST00000267620.10
 FBLN5
fibulin 5
chr3_-_114035026 0.446 ENST00000570269.1
 RP11-553L6.5
RP11-553L6.5
chr9_+_96338647 0.434 ENST00000359246.4
 PHF2
PHD finger protein 2
chr18_-_53303123 0.392 ENST00000569357.1
ENST00000565124.1
ENST00000398339.1
 TCF4


transcription factor 4


chr9_+_96338860 0.355 ENST00000375376.4
 PHF2
PHD finger protein 2
chr1_-_32801825 0.325 ENST00000329421.7
 MARCKSL1
MARCKS-like 1
chr3_-_79816965 0.299 ENST00000464233.1
 ROBO1
roundabout, axon guidance receptor, homolog 1 (Drosophila)
chr14_-_21979428 0.276 ENST00000538267.1
ENST00000298717.4
 METTL3

methyltransferase like 3

chr14_-_92413353 0.271 ENST00000556154.1
 FBLN5
fibulin 5
chr1_-_144995074 0.262 ENST00000534536.1
 PDE4DIP
phosphodiesterase 4D interacting protein
chr19_-_36545128 0.252 ENST00000538849.1
 THAP8
THAP domain containing 8
chr3_+_30647994 0.223 ENST00000295754.5
 TGFBR2
transforming growth factor, beta receptor II (70/80kDa)
chr1_-_144994909 0.212 ENST00000369347.4
ENST00000369354.3
 PDE4DIP

phosphodiesterase 4D interacting protein

chr14_-_53619816 0.198 ENST00000323669.5
ENST00000395606.1
ENST00000357758.3
 DDHD1


DDHD domain containing 1



Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 12 of 12 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.1 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.3 0.8 GO:0061188 negative regulation of chromatin silencing at rDNA(GO:0061188)
0.1 0.7 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 0.6 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.1 0.4 GO:0002514 B cell tolerance induction(GO:0002514) regulation of B cell tolerance induction(GO:0002661) positive regulation of B cell tolerance induction(GO:0002663)
0.1 0.3 GO:0021823 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836)
0.1 0.3 GO:0006382 adenosine to inosine editing(GO:0006382)
0.0 0.2 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.1 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.0 0.1 GO:2000974 auditory receptor cell fate determination(GO:0042668) negative regulation of pro-B cell differentiation(GO:2000974)
0.0 0.1 GO:0051083 'de novo' cotranslational protein folding(GO:0051083)
0.0 0.1 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)

Gene overrepresentation in cellular_component category:

Showing 1 to 4 of 4 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 0.7 GO:0071953 elastic fiber(GO:0071953)
0.0 0.4 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.1 0.3 GO:0036396 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.0 0.1 GO:0016602 CCAAT-binding factor complex(GO:0016602)

Gene overrepresentation in molecular_function category:

Showing 1 to 7 of 7 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.8 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.1 0.4 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
0.0 0.4 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 0.3 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.0 0.3 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.2 GO:0001855 complement component C4b binding(GO:0001855)
0.0 0.1 GO:0008969 phosphohistidine phosphatase activity(GO:0008969)

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 4 of 4 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.6 REACTOME_MRNA_3_END_PROCESSING Genes involved in mRNA 3'-end processing
0.0 0.4 REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.3 REACTOME_ACTIVATION_OF_RAC Genes involved in Activation of Rac
0.0 0.2 REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS Genes involved in Creation of C4 and C2 activators