Motif ID: GZF1

Z-value: 0.344


Transcription factors associated with GZF1:

Gene SymbolEntrez IDGene Name
GZF1 ENSG00000125812.11 GZF1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
GZF1hg19_v2_chr20_+_23342783_233429570.405.6e-02Click!


Activity profile for motif GZF1.

activity profile for motif GZF1


Sorted Z-values histogram for motif GZF1

Sorted Z-values for motif GZF1



Network of associatons between targets according to the STRING database.



First level regulatory network of GZF1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr11_+_101918153 1.373 ENST00000434758.2
ENST00000526781.1
ENST00000534360.1
 C11orf70


chromosome 11 open reading frame 70


chr1_+_79115503 0.637 ENST00000370747.4
ENST00000438486.1
ENST00000545124.1
 IFI44


interferon-induced protein 44


chr9_-_124976185 0.556 ENST00000464484.2
 LHX6
LIM homeobox 6
chr9_-_124976154 0.556 ENST00000482062.1
 LHX6
LIM homeobox 6
chr20_+_42086525 0.551 ENST00000244020.3
 SRSF6
serine/arginine-rich splicing factor 6
chr12_+_104458235 0.498 ENST00000229330.4
 HCFC2
host cell factor C2
chr14_-_92413727 0.458 ENST00000267620.10
 FBLN5
fibulin 5
chr3_-_114035026 0.446 ENST00000570269.1
 RP11-553L6.5
RP11-553L6.5
chr9_+_96338647 0.434 ENST00000359246.4
 PHF2
PHD finger protein 2
chr18_-_53303123 0.392 ENST00000569357.1
ENST00000565124.1
ENST00000398339.1
 TCF4


transcription factor 4


chr9_+_96338860 0.355 ENST00000375376.4
 PHF2
PHD finger protein 2
chr1_-_32801825 0.325 ENST00000329421.7
 MARCKSL1
MARCKS-like 1
chr3_-_79816965 0.299 ENST00000464233.1
 ROBO1
roundabout, axon guidance receptor, homolog 1 (Drosophila)
chr14_-_21979428 0.276 ENST00000538267.1
ENST00000298717.4
 METTL3

methyltransferase like 3

chr14_-_92413353 0.271 ENST00000556154.1
 FBLN5
fibulin 5
chr1_-_144995074 0.262 ENST00000534536.1
 PDE4DIP
phosphodiesterase 4D interacting protein
chr19_-_36545128 0.252 ENST00000538849.1
 THAP8
THAP domain containing 8
chr3_+_30647994 0.223 ENST00000295754.5
 TGFBR2
transforming growth factor, beta receptor II (70/80kDa)
chr1_-_144994909 0.212 ENST00000369347.4
ENST00000369354.3
 PDE4DIP

phosphodiesterase 4D interacting protein

chr14_-_53619816 0.198 ENST00000323669.5
ENST00000395606.1
ENST00000357758.3
 DDHD1


DDHD domain containing 1


chr1_-_11107280 0.195 ENST00000400897.3
ENST00000400898.3
 MASP2

mannan-binding lectin serine peptidase 2

chr1_-_144995002 0.177 ENST00000369356.4
 PDE4DIP
phosphodiesterase 4D interacting protein
chr15_+_44580955 0.173 ENST00000345795.2
ENST00000360824.3
 CASC4

cancer susceptibility candidate 4

chr20_-_31331212 0.164 ENST00000474815.2
ENST00000446419.2
 COMMD7

COMM domain containing 7

chr8_+_23430157 0.155 ENST00000399967.3
 FP15737
FP15737
chr3_+_30648066 0.133 ENST00000359013.4
 TGFBR2
transforming growth factor, beta receptor II (70/80kDa)
chr2_-_27603582 0.126 ENST00000323703.6
ENST00000436006.1
 ZNF513

zinc finger protein 513

chr16_+_67876180 0.126 ENST00000303596.1
 THAP11
THAP domain containing 11
chr10_+_60028818 0.125 ENST00000333926.5
 CISD1
CDGSH iron sulfur domain 1
chr10_+_89264625 0.123 ENST00000371996.4
ENST00000371994.4
 MINPP1

multiple inositol-polyphosphate phosphatase 1

chrX_+_102883620 0.121 ENST00000372626.3
 TCEAL1
transcription elongation factor A (SII)-like 1
chr1_+_41174988 0.121 ENST00000372652.1
 NFYC
nuclear transcription factor Y, gamma
chr16_-_30582888 0.119 ENST00000563707.1
ENST00000567855.1
 ZNF688

zinc finger protein 688

chr4_-_89619386 0.100 ENST00000323061.5
 NAP1L5
nucleosome assembly protein 1-like 5
chr9_-_14308004 0.097 ENST00000493697.1
 NFIB
nuclear factor I/B
chr19_-_52150053 0.079 ENST00000222107.4
ENST00000360844.6
ENST00000599649.1
ENST00000429354.3
 SIGLEC5
SIGLEC14
SIGLEC5

sialic acid binding Ig-like lectin 5
sialic acid binding Ig-like lectin 14
SIGLEC5

chr3_+_51705222 0.079 ENST00000457573.1
ENST00000341333.5
ENST00000412249.1
ENST00000425781.1
ENST00000415259.1
ENST00000395057.1
ENST00000416589.1
 TEX264






testis expressed 264






chr1_-_144994840 0.076 ENST00000369351.3
ENST00000369349.3
 PDE4DIP

phosphodiesterase 4D interacting protein

chr16_+_87636474 0.076 ENST00000284262.2
 JPH3
junctophilin 3
chr10_+_14880287 0.067 ENST00000437161.2
 HSPA14
heat shock 70kDa protein 14
chr16_-_46797149 0.064 ENST00000536476.1
 MYLK3
myosin light chain kinase 3
chr1_-_2461684 0.062 ENST00000378453.3
 HES5
hes family bHLH transcription factor 5
chr19_+_36157715 0.056 ENST00000379013.2
ENST00000222275.2
 UPK1A

uroplakin 1A

chr5_+_92919043 0.044 ENST00000327111.3
 NR2F1
nuclear receptor subfamily 2, group F, member 1
chr22_-_43355858 0.042 ENST00000402229.1
ENST00000407585.1
ENST00000453079.1
 PACSIN2


protein kinase C and casein kinase substrate in neurons 2


chr17_-_70588936 0.037 ENST00000453722.2
 LINC00511
long intergenic non-protein coding RNA 511
chr10_-_126849588 0.031 ENST00000411419.2
 CTBP2
C-terminal binding protein 2
chr10_-_126849068 0.017 ENST00000494626.2
ENST00000337195.5
 CTBP2

C-terminal binding protein 2

chr19_-_10426663 0.016 ENST00000541276.1
ENST00000393708.3
ENST00000494368.1
 FDX1L


ferredoxin 1-like


chr8_+_144373550 0.016 ENST00000330143.3
ENST00000521537.1
ENST00000518432.1
ENST00000520333.1
 ZNF696



zinc finger protein 696



chr4_-_147443043 0.015 ENST00000394059.4
ENST00000502607.1
ENST00000335472.7
ENST00000432059.2
ENST00000394062.3
 SLC10A7




solute carrier family 10, member 7




chr10_-_14880566 0.014 ENST00000378442.1
 CDNF
cerebral dopamine neurotrophic factor
chr7_-_105029812 0.009 ENST00000482897.1
 SRPK2
SRSF protein kinase 2
chr14_+_22293618 0.006 ENST00000390432.2
 TRAV10
T cell receptor alpha variable 10
chr16_-_70285797 0.001 ENST00000435634.1
 EXOSC6
exosome component 6

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0061188 negative regulation of chromatin silencing at rDNA(GO:0061188)
0.1 0.4 GO:0002514 B cell tolerance induction(GO:0002514) regulation of B cell tolerance induction(GO:0002661) positive regulation of B cell tolerance induction(GO:0002663)
0.1 0.3 GO:0021823 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836)
0.1 1.1 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.1 0.6 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.1 0.7 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 0.3 GO:0006382 adenosine to inosine editing(GO:0006382)
0.0 0.1 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.0 0.1 GO:2000974 auditory receptor cell fate determination(GO:0042668) negative regulation of pro-B cell differentiation(GO:2000974)
0.0 0.1 GO:0051083 'de novo' cotranslational protein folding(GO:0051083)
0.0 0.2 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.1 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0071953 elastic fiber(GO:0071953)
0.1 0.3 GO:0036396 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.0 0.4 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 0.1 GO:0016602 CCAAT-binding factor complex(GO:0016602)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.1 0.4 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
0.0 0.2 GO:0001855 complement component C4b binding(GO:0001855)
0.0 0.8 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.1 GO:0008969 phosphohistidine phosphatase activity(GO:0008969)
0.0 0.3 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.4 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.4 REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.3 REACTOME_ACTIVATION_OF_RAC Genes involved in Activation of Rac
0.0 0.6 REACTOME_MRNA_3_END_PROCESSING Genes involved in mRNA 3'-end processing