Motif ID: HBP1
Z-value: 0.648
Transcription factors associated with HBP1:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| HBP1 | ENSG00000105856.9 | HBP1 |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| HBP1 | hg19_v2_chr7_+_106809406_106809460 | -0.16 | 4.6e-01 | Click! |
Top targets:
Showing 1 to 20 of 200 entries
Gene overrepresentation in biological_process category:
Showing 1 to 20 of 93 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 3.0 | GO:1901750 | leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750) |
| 0.2 | 2.7 | GO:0038044 | transforming growth factor-beta secretion(GO:0038044) |
| 0.1 | 2.4 | GO:0000188 | inactivation of MAPK activity(GO:0000188) |
| 0.6 | 1.9 | GO:0060557 | positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559) |
| 0.1 | 1.8 | GO:0015693 | magnesium ion transport(GO:0015693) |
| 0.6 | 1.7 | GO:0042663 | regulation of endodermal cell fate specification(GO:0042663) |
| 0.0 | 1.7 | GO:0030317 | sperm motility(GO:0030317) |
| 0.3 | 1.6 | GO:0007296 | vitellogenesis(GO:0007296) |
| 0.5 | 1.4 | GO:0019242 | methylglyoxal biosynthetic process(GO:0019242) |
| 0.4 | 1.3 | GO:0019072 | viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074) |
| 0.0 | 1.3 | GO:2000249 | regulation of actin cytoskeleton reorganization(GO:2000249) |
| 0.1 | 1.2 | GO:0010668 | ectodermal cell differentiation(GO:0010668) |
| 0.0 | 1.2 | GO:1902808 | positive regulation of cell cycle G1/S phase transition(GO:1902808) |
| 0.0 | 1.0 | GO:0032392 | DNA geometric change(GO:0032392) |
| 0.3 | 0.9 | GO:0042450 | arginine biosynthetic process via ornithine(GO:0042450) |
| 0.1 | 0.9 | GO:0002191 | cap-dependent translational initiation(GO:0002191) |
| 0.1 | 0.9 | GO:0019388 | galactose catabolic process(GO:0019388) |
| 0.0 | 0.9 | GO:0030049 | muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275) |
| 0.2 | 0.8 | GO:0000103 | sulfate assimilation(GO:0000103) |
| 0.1 | 0.8 | GO:0034983 | peptidyl-lysine deacetylation(GO:0034983) |
Gene overrepresentation in cellular_component category:
Showing 1 to 20 of 42 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.9 | 2.7 | GO:0034685 | integrin alphav-beta6 complex(GO:0034685) |
| 0.0 | 2.3 | GO:0030864 | cortical actin cytoskeleton(GO:0030864) |
| 0.0 | 1.8 | GO:0042734 | presynaptic membrane(GO:0042734) |
| 0.0 | 1.6 | GO:0060170 | ciliary membrane(GO:0060170) |
| 0.1 | 1.3 | GO:0031298 | replication fork protection complex(GO:0031298) |
| 0.4 | 1.2 | GO:0034676 | integrin alpha6-beta4 complex(GO:0034676) |
| 0.1 | 1.2 | GO:0097431 | mitotic spindle pole(GO:0097431) |
| 0.1 | 1.0 | GO:0043219 | lateral loop(GO:0043219) |
| 0.0 | 0.9 | GO:0016281 | eukaryotic translation initiation factor 4F complex(GO:0016281) |
| 0.1 | 0.8 | GO:0000015 | phosphopyruvate hydratase complex(GO:0000015) |
| 0.0 | 0.8 | GO:0005862 | muscle thin filament tropomyosin(GO:0005862) |
| 0.0 | 0.8 | GO:0030687 | preribosome, large subunit precursor(GO:0030687) |
| 0.0 | 0.7 | GO:0042622 | photoreceptor outer segment membrane(GO:0042622) |
| 0.1 | 0.6 | GO:0031166 | integral component of vacuolar membrane(GO:0031166) |
| 0.0 | 0.5 | GO:0043034 | costamere(GO:0043034) |
| 0.0 | 0.4 | GO:0000930 | gamma-tubulin complex(GO:0000930) |
| 0.1 | 0.3 | GO:0097129 | cyclin D2-CDK4 complex(GO:0097129) |
| 0.0 | 0.3 | GO:0000176 | nuclear exosome (RNase complex)(GO:0000176) |
| 0.0 | 0.3 | GO:0005641 | nuclear envelope lumen(GO:0005641) |
| 0.0 | 0.3 | GO:0005847 | mRNA cleavage and polyadenylation specificity factor complex(GO:0005847) |
Gene overrepresentation in molecular_function category:
Showing 1 to 20 of 71 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 3.3 | GO:0033549 | MAP kinase phosphatase activity(GO:0033549) |
| 0.2 | 3.0 | GO:0036374 | glutathione hydrolase activity(GO:0036374) |
| 0.0 | 2.7 | GO:0001618 | virus receptor activity(GO:0001618) |
| 0.1 | 1.9 | GO:0005149 | interleukin-1 receptor binding(GO:0005149) |
| 0.1 | 1.8 | GO:0015095 | magnesium ion transmembrane transporter activity(GO:0015095) |
| 0.5 | 1.4 | GO:0004347 | glucose-6-phosphate isomerase activity(GO:0004347) |
| 0.1 | 1.3 | GO:0004075 | biotin carboxylase activity(GO:0004075) biotin binding(GO:0009374) |
| 0.1 | 1.2 | GO:0038132 | neuregulin binding(GO:0038132) |
| 0.0 | 1.2 | GO:0019894 | kinesin binding(GO:0019894) |
| 0.2 | 0.9 | GO:0003974 | UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978) |
| 0.1 | 0.9 | GO:0016842 | amidine-lyase activity(GO:0016842) |
| 0.0 | 0.9 | GO:0008190 | eukaryotic initiation factor 4E binding(GO:0008190) |
| 0.0 | 0.9 | GO:0000400 | four-way junction DNA binding(GO:0000400) |
| 0.2 | 0.8 | GO:0004782 | sulfinoalanine decarboxylase activity(GO:0004782) |
| 0.2 | 0.8 | GO:0045134 | uridine-diphosphatase activity(GO:0045134) |
| 0.1 | 0.8 | GO:0050294 | steroid sulfotransferase activity(GO:0050294) |
| 0.1 | 0.8 | GO:0004634 | phosphopyruvate hydratase activity(GO:0004634) |
| 0.0 | 0.8 | GO:0031078 | histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041) |
| 0.0 | 0.8 | GO:0070412 | R-SMAD binding(GO:0070412) |
| 0.2 | 0.7 | GO:0004821 | histidine-tRNA ligase activity(GO:0004821) |
Gene overrepresentation in C2:CP category:
Showing 1 to 13 of 13 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 2.7 | PID_INTEGRIN5_PATHWAY | Beta5 beta6 beta7 and beta8 integrin cell surface interactions |
| 0.1 | 2.1 | SA_MMP_CYTOKINE_CONNECTION | Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix. |
| 0.0 | 1.7 | PID_TCR_CALCIUM_PATHWAY | Calcium signaling in the CD4+ TCR pathway |
| 0.0 | 1.6 | ST_ERK1_ERK2_MAPK_PATHWAY | ERK1/ERK2 MAPK Pathway |
| 0.1 | 1.2 | PID_INTEGRIN4_PATHWAY | Alpha6 beta4 integrin-ligand interactions |
| 0.0 | 0.9 | PID_ECADHERIN_NASCENT_AJ_PATHWAY | E-cadherin signaling in the nascent adherens junction |
| 0.0 | 0.9 | PID_ATR_PATHWAY | ATR signaling pathway |
| 0.0 | 0.8 | PID_EPHRINB_REV_PATHWAY | Ephrin B reverse signaling |
| 0.0 | 0.8 | PID_BCR_5PATHWAY | BCR signaling pathway |
| 0.0 | 0.8 | PID_ILK_PATHWAY | Integrin-linked kinase signaling |
| 0.0 | 0.7 | PID_RHODOPSIN_PATHWAY | Visual signal transduction: Rods |
| 0.0 | 0.6 | PID_LIS1_PATHWAY | Lissencephaly gene (LIS1) in neuronal migration and development |
| 0.0 | 0.3 | SA_REG_CASCADE_OF_CYCLIN_EXPR | Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases. |
Gene overrepresentation in C2:CP:REACTOME category:
Showing 1 to 20 of 21 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 3.5 | REACTOME_GLUCONEOGENESIS | Genes involved in Gluconeogenesis |
| 0.2 | 3.3 | REACTOME_ERKS_ARE_INACTIVATED | Genes involved in ERKs are inactivated |
| 0.0 | 2.7 | REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS | Genes involved in Integrin cell surface interactions |
| 0.0 | 2.0 | REACTOME_IL1_SIGNALING | Genes involved in Interleukin-1 signaling |
| 0.0 | 1.1 | REACTOME_ACTIVATION_OF_ATR_IN_RESPONSE_TO_REPLICATION_STRESS | Genes involved in Activation of ATR in response to replication stress |
| 0.0 | 1.0 | REACTOME_TGF_BETA_RECEPTOR_SIGNALING_ACTIVATES_SMADS | Genes involved in TGF-beta receptor signaling activates SMADs |
| 0.0 | 0.9 | REACTOME_MTORC1_MEDIATED_SIGNALLING | Genes involved in mTORC1-mediated signalling |
| 0.0 | 0.8 | REACTOME_CYTOSOLIC_SULFONATION_OF_SMALL_MOLECULES | Genes involved in Cytosolic sulfonation of small molecules |
| 0.0 | 0.8 | REACTOME_SMOOTH_MUSCLE_CONTRACTION | Genes involved in Smooth Muscle Contraction |
| 0.0 | 0.7 | REACTOME_AMINE_DERIVED_HORMONES | Genes involved in Amine-derived hormones |
| 0.0 | 0.6 | REACTOME_TAK1_ACTIVATES_NFKB_BY_PHOSPHORYLATION_AND_ACTIVATION_OF_IKKS_COMPLEX | Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex |
| 0.0 | 0.6 | REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS | Genes involved in Ionotropic activity of Kainate Receptors |
| 0.0 | 0.6 | REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION | Genes involved in Cytosolic tRNA aminoacylation |
| 0.0 | 0.6 | REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE | Genes involved in Amino acid transport across the plasma membrane |
| 0.0 | 0.5 | REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS | Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis |
| 0.0 | 0.4 | REACTOME_TRNA_AMINOACYLATION | Genes involved in tRNA Aminoacylation |
| 0.0 | 0.3 | REACTOME_SYNTHESIS_OF_SUBSTRATES_IN_N_GLYCAN_BIOSYTHESIS | Genes involved in Synthesis of substrates in N-glycan biosythesis |
| 0.0 | 0.3 | REACTOME_PROCESSING_OF_INTRONLESS_PRE_MRNAS | Genes involved in Processing of Intronless Pre-mRNAs |
| 0.0 | 0.3 | REACTOME_SYNTHESIS_SECRETION_AND_DEACYLATION_OF_GHRELIN | Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin |
| 0.0 | 0.2 | REACTOME_XENOBIOTICS | Genes involved in Xenobiotics |
