Motif ID: HDX

Z-value: 0.231


Transcription factors associated with HDX:

Gene SymbolEntrez IDGene Name
HDX ENSG00000165259.9 HDX

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
HDXhg19_v2_chrX_-_83757399_837574870.331.1e-01Click!


Activity profile for motif HDX.

activity profile for motif HDX


Sorted Z-values histogram for motif HDX

Sorted Z-values for motif HDX



Network of associatons between targets according to the STRING database.



First level regulatory network of HDX

PNG image of the network

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Top targets:


Showing 1 to 20 of 43 entries
PromoterScoreRefseqGene SymbolGene Name
chr2_-_113594279 0.255 ENST00000416750.1
ENST00000418817.1
ENST00000263341.2
 IL1B


interleukin 1, beta


chr5_-_35230434 0.217 ENST00000504500.1
 PRLR
prolactin receptor
chr7_-_69062391 0.206 ENST00000436600.2
 RP5-942I16.1
RP5-942I16.1
chr2_+_128403720 0.190 ENST00000272644.3
 GPR17
G protein-coupled receptor 17
chr12_+_101869096 0.181 ENST00000551346.1
 SPIC
Spi-C transcription factor (Spi-1/PU.1 related)
chr2_+_128403439 0.179 ENST00000544369.1
 GPR17
G protein-coupled receptor 17
chr1_+_84630053 0.142 ENST00000394838.2
ENST00000370682.3
ENST00000432111.1
 PRKACB


protein kinase, cAMP-dependent, catalytic, beta


chr18_+_29027696 0.140 ENST00000257189.4
 DSG3
desmoglein 3
chr7_-_121944491 0.123 ENST00000331178.4
ENST00000427185.2
ENST00000442488.2
 FEZF1


FEZ family zinc finger 1


chr12_+_10460549 0.118 ENST00000543420.1
ENST00000543777.1
 KLRD1

killer cell lectin-like receptor subfamily D, member 1

chr2_+_113735575 0.113 ENST00000376489.2
ENST00000259205.4
 IL36G

interleukin 36, gamma

chr5_+_60933634 0.094 ENST00000505642.1
 C5orf64
chromosome 5 open reading frame 64
chr5_-_41213607 0.094 ENST00000337836.5
ENST00000433294.1
 C6

complement component 6

chr1_+_117602925 0.087 ENST00000369466.4
 TTF2
transcription termination factor, RNA polymerase II
chr10_-_14372870 0.085 ENST00000357447.2
 FRMD4A
FERM domain containing 4A
chr3_-_165555200 0.085 ENST00000479451.1
ENST00000540653.1
ENST00000488954.1
ENST00000264381.3
 BCHE



butyrylcholinesterase



chr12_+_10460417 0.074 ENST00000381908.3
ENST00000336164.4
ENST00000350274.5
 KLRD1


killer cell lectin-like receptor subfamily D, member 1


chr7_+_99954224 0.073 ENST00000608825.1
 PILRB
paired immunoglobin-like type 2 receptor beta
chr9_+_35538616 0.064 ENST00000455600.1
 RUSC2
RUN and SH3 domain containing 2
chr12_+_54422142 0.058 ENST00000243108.4
 HOXC6
homeobox C6

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 7 of 7 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.4 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.1 0.3 GO:0060557 positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
0.0 0.3 GO:0038161 prolactin signaling pathway(GO:0038161)
0.0 0.1 GO:0014016 neuroblast differentiation(GO:0014016)
0.0 0.1 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.0 0.1 GO:0001970 positive regulation of activation of membrane attack complex(GO:0001970)
0.0 0.1 GO:0097338 response to clozapine(GO:0097338)

Gene overrepresentation in cellular_component category:

Showing 1 to 1 of 1 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.1 GO:0005579 membrane attack complex(GO:0005579)

Gene overrepresentation in molecular_function category:

Showing 1 to 4 of 4 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.4 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.1 0.3 GO:0004925 prolactin receptor activity(GO:0004925)
0.0 0.2 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.0 0.1 GO:0003990 acetylcholinesterase activity(GO:0003990)

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 2 of 2 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.4 REACTOME_P2Y_RECEPTORS Genes involved in P2Y receptors
0.0 0.3 REACTOME_PROLACTIN_RECEPTOR_SIGNALING Genes involved in Prolactin receptor signaling