Motif ID: HIC1

Z-value: 0.789


Transcription factors associated with HIC1:

Gene SymbolEntrez IDGene Name
HIC1 ENSG00000177374.8 HIC1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
HIC1hg19_v2_chr17_+_1959369_1959604,
hg19_v2_chr17_+_1958388_1958404
0.048.7e-01Click!


Activity profile for motif HIC1.

activity profile for motif HIC1


Sorted Z-values histogram for motif HIC1

Sorted Z-values for motif HIC1



Network of associatons between targets according to the STRING database.



First level regulatory network of HIC1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr11_-_2160611 1.122 ENST00000416167.2
IGF2
insulin-like growth factor 2 (somatomedin A)
chr12_+_26274917 0.705 ENST00000538142.1
SSPN
sarcospan
chr12_-_132905789 0.704 ENST00000328957.8
GALNT9
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 9 (GalNAc-T9)
chr18_+_77623668 0.673 ENST00000316249.3
KCNG2
potassium voltage-gated channel, subfamily G, member 2
chr13_+_110959598 0.652 ENST00000360467.5
COL4A2
collagen, type IV, alpha 2
chr9_+_22446814 0.636 ENST00000325870.2
DMRTA1
DMRT-like family A1
chr11_+_120382417 0.633 ENST00000527524.2
ENST00000375081.2
GRIK4
AP002348.1
glutamate receptor, ionotropic, kainate 4
Uncharacterized protein
chr4_+_3768075 0.588 ENST00000509482.1
ENST00000330055.5
ADRA2C

adrenoceptor alpha 2C

chr6_+_159590423 0.559 ENST00000297267.9
ENST00000340366.6
FNDC1

fibronectin type III domain containing 1

chr10_+_116853201 0.559 ENST00000527407.1
ATRNL1
attractin-like 1
chrX_-_45710920 0.549 ENST00000456532.1
RP5-1158E12.3
RP5-1158E12.3
chr1_+_1551220 0.547 ENST00000378712.1
MIB2
mindbomb E3 ubiquitin protein ligase 2
chr13_+_28712614 0.527 ENST00000380958.3
PAN3
PAN3 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)
chr7_+_70597109 0.515 ENST00000333538.5
WBSCR17
Williams-Beuren syndrome chromosome region 17
chr3_+_52280173 0.514 ENST00000296487.4
PPM1M
protein phosphatase, Mg2+/Mn2+ dependent, 1M
chr11_+_119019722 0.512 ENST00000307417.3
ABCG4
ATP-binding cassette, sub-family G (WHITE), member 4
chr5_+_6633456 0.511 ENST00000274192.5
SRD5A1
steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1)
chr1_-_62784935 0.508 ENST00000354381.3
KANK4
KN motif and ankyrin repeat domains 4
chr5_+_6633534 0.471 ENST00000537411.1
ENST00000538824.1
SRD5A1

steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1)

chr4_-_109684120 0.470 ENST00000512646.1
ENST00000411864.2
ENST00000296486.3
ENST00000510706.1
ETNPPL



ethanolamine-phosphate phospho-lyase



chr3_+_52280220 0.458 ENST00000409502.3
ENST00000323588.4
PPM1M

protein phosphatase, Mg2+/Mn2+ dependent, 1M

chr22_-_45404819 0.450 ENST00000447824.3
ENST00000404079.2
ENST00000420689.1
ENST00000403565.1
PHF21B



PHD finger protein 21B



chr13_-_44361025 0.438 ENST00000261488.6
ENOX1
ecto-NOX disulfide-thiol exchanger 1
chr10_+_72238517 0.438 ENST00000263563.6
PALD1
phosphatase domain containing, paladin 1
chr4_-_175443788 0.436 ENST00000541923.1
HPGD
hydroxyprostaglandin dehydrogenase 15-(NAD)
chr1_+_6845384 0.432 ENST00000303635.7
CAMTA1
calmodulin binding transcription activator 1
chr9_+_78505554 0.425 ENST00000545128.1
PCSK5
proprotein convertase subtilisin/kexin type 5
chr7_+_73082152 0.423 ENST00000324941.4
ENST00000451519.1
VPS37D

vacuolar protein sorting 37 homolog D (S. cerevisiae)

chr15_+_68871308 0.416 ENST00000261861.5
CORO2B
coronin, actin binding protein, 2B
chr13_-_45992541 0.401 ENST00000522438.1
SLC25A30
solute carrier family 25, member 30
chr14_+_105992906 0.400 ENST00000392519.2
TMEM121
transmembrane protein 121
chr16_-_1661988 0.397 ENST00000426508.2
IFT140
intraflagellar transport 140 homolog (Chlamydomonas)
chr19_+_35521616 0.388 ENST00000595652.1
SCN1B
sodium channel, voltage-gated, type I, beta subunit
chr10_+_122216316 0.385 ENST00000398250.1
ENST00000439221.1
ENST00000398248.1
PPAPDC1A


phosphatidic acid phosphatase type 2 domain containing 1A


chr17_-_80656528 0.380 ENST00000538809.2
ENST00000269347.6
ENST00000571995.1
RAB40B


RAB40B, member RAS oncogene family


chr22_-_50689640 0.373 ENST00000448072.1
HDAC10
histone deacetylase 10
chr16_-_755726 0.372 ENST00000324361.5
FBXL16
F-box and leucine-rich repeat protein 16
chr19_+_709101 0.372 ENST00000338448.5
PALM
paralemmin
chr16_+_1662326 0.370 ENST00000397412.3
CRAMP1L
Crm, cramped-like (Drosophila)
chr10_+_71562180 0.369 ENST00000517713.1
ENST00000522165.1
ENST00000520133.1
COL13A1


collagen, type XIII, alpha 1


chr2_-_165477971 0.360 ENST00000446413.2
GRB14
growth factor receptor-bound protein 14
chr19_+_708910 0.352 ENST00000264560.7
PALM
paralemmin
chr4_-_175443484 0.351 ENST00000514584.1
ENST00000542498.1
ENST00000296521.7
ENST00000422112.2
ENST00000504433.1
HPGD




hydroxyprostaglandin dehydrogenase 15-(NAD)




chr14_+_33408449 0.348 ENST00000346562.2
ENST00000341321.4
ENST00000548645.1
ENST00000356141.4
ENST00000357798.5
NPAS3




neuronal PAS domain protein 3




chr16_+_25703274 0.346 ENST00000331351.5
HS3ST4
heparan sulfate (glucosamine) 3-O-sulfotransferase 4
chr11_+_64059464 0.346 ENST00000394525.2
KCNK4
potassium channel, subfamily K, member 4
chrX_-_107018969 0.346 ENST00000372383.4
TSC22D3
TSC22 domain family, member 3
chr3_+_137483579 0.345 ENST00000306087.1
SOX14
SRY (sex determining region Y)-box 14
chr10_+_11784360 0.345 ENST00000379215.4
ENST00000420401.1
ECHDC3

enoyl CoA hydratase domain containing 3

chr6_-_41863098 0.338 ENST00000373006.1
USP49
ubiquitin specific peptidase 49
chr10_+_116853091 0.336 ENST00000526946.1
ATRNL1
attractin-like 1
chrX_-_128788914 0.335 ENST00000429967.1
ENST00000307484.6
APLN

apelin

chr3_-_127541679 0.334 ENST00000265052.5
MGLL
monoglyceride lipase
chrX_-_107019181 0.334 ENST00000315660.4
ENST00000372384.2
ENST00000502650.1
ENST00000506724.1
TSC22D3



TSC22 domain family, member 3



chr3_-_197024394 0.331 ENST00000434148.1
ENST00000412364.2
ENST00000436682.1
ENST00000456699.2
ENST00000392380.2
DLG1




discs, large homolog 1 (Drosophila)




chr1_-_62785054 0.329 ENST00000371153.4
KANK4
KN motif and ankyrin repeat domains 4
chr16_+_1756162 0.328 ENST00000250894.4
ENST00000356010.5
MAPK8IP3

mitogen-activated protein kinase 8 interacting protein 3

chr16_-_79633799 0.322 ENST00000569649.1
MAF
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
chr1_-_6240183 0.320 ENST00000262450.3
ENST00000378021.1
CHD5

chromodomain helicase DNA binding protein 5

chr11_+_65554493 0.318 ENST00000335987.3
OVOL1
ovo-like zinc finger 1
chr19_-_58874112 0.318 ENST00000311044.3
ENST00000595763.1
ENST00000425453.3
ZNF497


zinc finger protein 497


chr1_+_8378140 0.313 ENST00000377479.2
SLC45A1
solute carrier family 45, member 1
chr12_+_130646999 0.308 ENST00000539839.1
ENST00000229030.4
FZD10

frizzled family receptor 10

chr19_-_5340730 0.306 ENST00000372412.4
ENST00000357368.4
ENST00000262963.6
ENST00000348075.2
ENST00000353284.2
PTPRS




protein tyrosine phosphatase, receptor type, S




chr11_+_94822968 0.303 ENST00000278505.4
ENDOD1
endonuclease domain containing 1
chr4_+_148653206 0.301 ENST00000336498.3
ARHGAP10
Rho GTPase activating protein 10
chr22_+_23412479 0.299 ENST00000248996.4
GNAZ
guanine nucleotide binding protein (G protein), alpha z polypeptide
chr6_-_166401527 0.293 ENST00000455853.1
ENST00000584911.1
LINC00473

long intergenic non-protein coding RNA 473

chr4_+_4388805 0.292 ENST00000504171.1
NSG1
Homo sapiens neuron specific gene family member 1 (NSG1), transcript variant 3, mRNA.
chr17_+_7621045 0.290 ENST00000570791.1
DNAH2
dynein, axonemal, heavy chain 2
chr3_-_52739762 0.289 ENST00000487642.1
ENST00000464705.1
ENST00000491606.1
ENST00000489119.1
ENST00000478968.2
GLT8D1




glycosyltransferase 8 domain containing 1




chr2_+_207308539 0.289 ENST00000374416.1
ENST00000374415.3
ADAM23

ADAM metallopeptidase domain 23

chr10_-_126432821 0.287 ENST00000280780.6
FAM53B
family with sequence similarity 53, member B
chr6_+_43543942 0.284 ENST00000372226.1
ENST00000443535.1
POLH

polymerase (DNA directed), eta

chr4_-_185747188 0.281 ENST00000507295.1
ENST00000504900.1
ENST00000281455.2
ENST00000454703.2
ACSL1



acyl-CoA synthetase long-chain family member 1



chr8_+_27491381 0.281 ENST00000337221.4
SCARA3
scavenger receptor class A, member 3
chr19_+_41860047 0.279 ENST00000604123.1
TMEM91
transmembrane protein 91
chr22_-_19137796 0.279 ENST00000086933.2
GSC2
goosecoid homeobox 2
chr7_+_128577972 0.279 ENST00000357234.5
ENST00000477535.1
ENST00000479582.1
ENST00000464557.1
ENST00000402030.2
IRF5




interferon regulatory factor 5




chr9_+_78505581 0.273 ENST00000376767.3
ENST00000376752.4
PCSK5

proprotein convertase subtilisin/kexin type 5

chr17_+_79989500 0.272 ENST00000306897.4
RAC3
ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
chr17_+_4402133 0.272 ENST00000329078.3
SPNS2
spinster homolog 2 (Drosophila)
chr11_-_2160180 0.270 ENST00000381406.4
IGF2
insulin-like growth factor 2 (somatomedin A)
chr14_-_100625932 0.269 ENST00000553834.1
DEGS2
delta(4)-desaturase, sphingolipid 2
chr13_-_49107303 0.269 ENST00000344532.3
RCBTB2
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
chr20_+_23016057 0.269 ENST00000255008.3
SSTR4
somatostatin receptor 4
chr6_+_43543864 0.269 ENST00000372236.4
ENST00000535400.1
POLH

polymerase (DNA directed), eta

chr18_-_21242774 0.265 ENST00000322980.9
ANKRD29
ankyrin repeat domain 29
chr4_+_4388245 0.264 ENST00000433139.2
NSG1
Homo sapiens neuron specific gene family member 1 (NSG1), transcript variant 3, mRNA.
chr2_-_10220538 0.264 ENST00000381813.4
CYS1
cystin 1
chr6_+_56819895 0.264 ENST00000370748.3
BEND6
BEN domain containing 6
chr5_+_111755280 0.263 ENST00000600409.1
EPB41L4A-AS2
EPB41L4A antisense RNA 2 (head to head)
chr16_+_69140122 0.262 ENST00000219322.3
HAS3
hyaluronan synthase 3
chr6_-_105584560 0.261 ENST00000336775.5
BVES
blood vessel epicardial substance
chr5_-_168727713 0.261 ENST00000404867.3
SLIT3
slit homolog 3 (Drosophila)
chr18_-_21242833 0.256 ENST00000586087.1
ENST00000592179.1
ANKRD29

ankyrin repeat domain 29

chr2_+_204193129 0.255 ENST00000417864.1
ABI2
abl-interactor 2
chr2_+_96012397 0.255 ENST00000468529.1
KCNIP3
Kv channel interacting protein 3, calsenilin
chr17_+_40440481 0.255 ENST00000590726.2
ENST00000452307.2
ENST00000444283.1
ENST00000588868.1
STAT5A



signal transducer and activator of transcription 5A



chr9_+_133884469 0.254 ENST00000361069.4
LAMC3
laminin, gamma 3
chr1_+_66258846 0.252 ENST00000341517.4
PDE4B
phosphodiesterase 4B, cAMP-specific
chr4_+_4387983 0.252 ENST00000397958.1
NSG1
Homo sapiens neuron specific gene family member 1 (NSG1), transcript variant 3, mRNA.
chr3_-_52740012 0.251 ENST00000407584.3
ENST00000266014.5
GLT8D1

glycosyltransferase 8 domain containing 1

chr8_-_23261589 0.250 ENST00000524168.1
ENST00000523833.2
ENST00000519243.1
ENST00000389131.3
LOXL2



lysyl oxidase-like 2



chr2_+_204193149 0.250 ENST00000422511.2
ABI2
abl-interactor 2
chr10_-_104001231 0.250 ENST00000370002.3
PITX3
paired-like homeodomain 3
chr16_-_755819 0.245 ENST00000397621.1
FBXL16
F-box and leucine-rich repeat protein 16
chr12_-_122238464 0.245 ENST00000546227.1
RHOF
ras homolog family member F (in filopodia)
chr12_+_1929421 0.245 ENST00000543818.1
LRTM2
leucine-rich repeats and transmembrane domains 2
chr1_-_85358850 0.244 ENST00000370611.3
LPAR3
lysophosphatidic acid receptor 3
chr12_-_6756559 0.243 ENST00000536350.1
ENST00000414226.2
ENST00000546114.1
ACRBP


acrosin binding protein


chr12_+_1929783 0.243 ENST00000535041.1
LRTM2
leucine-rich repeats and transmembrane domains 2
chr1_-_111217603 0.242 ENST00000369769.2
KCNA3
potassium voltage-gated channel, shaker-related subfamily, member 3
chr16_+_67700673 0.240 ENST00000403458.4
ENST00000602365.1
C16orf86

chromosome 16 open reading frame 86

chr14_+_102027688 0.239 ENST00000510508.4
ENST00000359323.3
DIO3

deiodinase, iodothyronine, type III

chr12_+_53440753 0.237 ENST00000379902.3
TENC1
tensin like C1 domain containing phosphatase (tensin 2)
chr16_-_79634595 0.237 ENST00000326043.4
ENST00000393350.1
MAF

v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog

chr1_-_43919346 0.236 ENST00000372430.3
ENST00000372433.1
ENST00000372434.1
ENST00000486909.1
HYI



hydroxypyruvate isomerase (putative)



chr9_+_131182697 0.236 ENST00000372838.4
ENST00000411852.1
CERCAM

cerebral endothelial cell adhesion molecule

chr9_-_101471479 0.235 ENST00000259455.2
GABBR2
gamma-aminobutyric acid (GABA) B receptor, 2
chr12_+_1929644 0.235 ENST00000299194.1
LRTM2
leucine-rich repeats and transmembrane domains 2
chr1_-_241520525 0.234 ENST00000366565.1
RGS7
regulator of G-protein signaling 7
chr19_-_49140609 0.232 ENST00000601104.1
DBP
D site of albumin promoter (albumin D-box) binding protein
chr14_+_21152706 0.231 ENST00000397995.2
ENST00000304704.4
ENST00000553909.1
RNASE4

AL163636.6
ribonuclease, RNase A family, 4

Homo sapiens ribonuclease, RNase A family, 4 (RNASE4), transcript variant 4, mRNA.
chr12_+_128751948 0.231 ENST00000435159.2
TMEM132C
transmembrane protein 132C
chr16_+_2076869 0.231 ENST00000424542.2
ENST00000432365.2
SLC9A3R2

solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2

chr2_+_120770645 0.231 ENST00000443902.2
EPB41L5
erythrocyte membrane protein band 4.1 like 5
chr1_+_150521876 0.230 ENST00000369041.5
ENST00000271643.4
ENST00000538795.1
ADAMTSL4

AL356356.1
ADAMTS-like 4

Protein LOC100996516
chr15_+_68871569 0.227 ENST00000566799.1
CORO2B
coronin, actin binding protein, 2B
chrX_-_153363125 0.227 ENST00000407218.1
ENST00000453960.2
MECP2

methyl CpG binding protein 2 (Rett syndrome)

chr2_-_27718052 0.226 ENST00000264703.3
FNDC4
fibronectin type III domain containing 4
chr12_-_6756609 0.226 ENST00000229243.2
ACRBP
acrosin binding protein
chr2_+_7057523 0.226 ENST00000320892.6
RNF144A
ring finger protein 144A
chr20_+_57430162 0.226 ENST00000450130.1
ENST00000349036.3
ENST00000423897.1
GNAS


GNAS complex locus


chr4_+_150999418 0.224 ENST00000296550.7
DCLK2
doublecortin-like kinase 2
chr2_-_177502659 0.223 ENST00000295549.4
AC017048.3
long intergenic non-protein coding RNA 1116
chr9_-_136933615 0.223 ENST00000371834.2
BRD3
bromodomain containing 3
chr22_+_43808014 0.222 ENST00000334209.5
ENST00000443721.1
ENST00000414469.2
ENST00000439548.1
MPPED1



metallophosphoesterase domain containing 1



chr19_-_5567996 0.221 ENST00000448587.1
TINCR
tissue differentiation-inducing non-protein coding RNA
chr19_-_17559376 0.220 ENST00000341130.5
TMEM221
transmembrane protein 221
chr4_-_175443943 0.219 ENST00000296522.6
HPGD
hydroxyprostaglandin dehydrogenase 15-(NAD)
chr16_-_31439735 0.219 ENST00000287490.4
COX6A2
cytochrome c oxidase subunit VIa polypeptide 2
chr16_-_28074822 0.218 ENST00000395724.3
ENST00000380898.2
ENST00000447459.2
GSG1L


GSG1-like


chr22_+_50609150 0.216 ENST00000159647.5
ENST00000395842.2
PANX2

pannexin 2

chr8_-_125740514 0.216 ENST00000325064.5
ENST00000518547.1
MTSS1

metastasis suppressor 1

chr6_+_147830063 0.216 ENST00000367474.1
SAMD5
sterile alpha motif domain containing 5
chr15_+_33603147 0.215 ENST00000415757.3
ENST00000389232.4
RYR3

ryanodine receptor 3

chr10_+_17271266 0.215 ENST00000224237.5
VIM
vimentin
chr12_-_45270151 0.214 ENST00000429094.2
NELL2
NEL-like 2 (chicken)
chr11_-_6677018 0.213 ENST00000299441.3
DCHS1
dachsous cadherin-related 1
chr19_-_51143075 0.213 ENST00000600079.1
ENST00000593901.1
SYT3

synaptotagmin III

chr17_+_73084038 0.213 ENST00000578376.1
ENST00000329783.4
SLC16A5

solute carrier family 16 (monocarboxylate transporter), member 5

chr6_-_105627735 0.212 ENST00000254765.3
POPDC3
popeye domain containing 3
chr19_+_42746927 0.211 ENST00000378108.1
AC006486.1
AC006486.1
chr14_-_53162361 0.210 ENST00000395686.3
ERO1L
ERO1-like (S. cerevisiae)
chr17_+_79373540 0.209 ENST00000307745.7
RP11-1055B8.7
BAH and coiled-coil domain-containing protein 1
chr15_+_63340775 0.208 ENST00000559281.1
ENST00000317516.7
TPM1

tropomyosin 1 (alpha)

chr16_+_2521500 0.208 ENST00000293973.1
NTN3
netrin 3
chr6_+_56819773 0.208 ENST00000370750.2
BEND6
BEN domain containing 6
chr19_-_38746979 0.207 ENST00000591291.1
PPP1R14A
protein phosphatase 1, regulatory (inhibitor) subunit 14A
chr8_-_144651024 0.206 ENST00000524906.1
ENST00000532862.1
ENST00000534459.1
MROH6


maestro heat-like repeat family member 6


chr19_-_41859814 0.206 ENST00000221930.5
TGFB1
transforming growth factor, beta 1
chr20_-_62680984 0.205 ENST00000340356.7
SOX18
SRY (sex determining region Y)-box 18
chr12_-_45270077 0.205 ENST00000551601.1
ENST00000549027.1
ENST00000452445.2
NELL2


NEL-like 2 (chicken)


chr21_+_44073860 0.205 ENST00000335512.4
ENST00000539837.1
ENST00000291539.6
ENST00000380328.2
ENST00000398232.3
ENST00000398234.3
ENST00000398236.3
ENST00000328862.6
ENST00000335440.6
ENST00000398225.3
ENST00000398229.3
ENST00000398227.3
PDE9A











phosphodiesterase 9A











chr19_-_38747172 0.205 ENST00000347262.4
ENST00000591585.1
ENST00000301242.4
PPP1R14A


protein phosphatase 1, regulatory (inhibitor) subunit 14A


chr1_-_109940550 0.204 ENST00000256637.6
SORT1
sortilin 1
chr21_+_46359907 0.203 ENST00000291634.6
ENST00000397826.3
ENST00000458015.1
FAM207A


family with sequence similarity 207, member A


chr8_+_144349606 0.202 ENST00000521682.1
ENST00000340042.1
GLI4

GLI family zinc finger 4

chr5_-_171881362 0.202 ENST00000519643.1
SH3PXD2B
SH3 and PX domains 2B
chr17_+_73083816 0.202 ENST00000580123.1
ENST00000578847.1
SLC16A5

solute carrier family 16 (monocarboxylate transporter), member 5

chr7_-_150946015 0.202 ENST00000262188.8
SMARCD3
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
chr18_+_72265084 0.202 ENST00000582337.1
ZNF407
zinc finger protein 407
chr1_+_24829384 0.202 ENST00000374395.4
ENST00000436717.2
RCAN3

RCAN family member 3

chr4_+_2965307 0.202 ENST00000398051.4
ENST00000503518.2
ENST00000398052.4
ENST00000345167.6
ENST00000504933.1
ENST00000442472.2
GRK4





G protein-coupled receptor kinase 4





chr1_-_43919573 0.201 ENST00000372432.1
ENST00000372425.4
ENST00000583037.1
HYI


hydroxypyruvate isomerase (putative)


chr7_-_140624499 0.200 ENST00000288602.6
BRAF
v-raf murine sarcoma viral oncogene homolog B
chr1_+_205473720 0.199 ENST00000429964.2
ENST00000506784.1
ENST00000360066.2
CDK18


cyclin-dependent kinase 18


chr6_-_2876744 0.198 ENST00000420981.2
RP11-420G6.4
RP11-420G6.4
chr3_-_142682178 0.198 ENST00000340634.3
PAQR9
progestin and adipoQ receptor family member IX
chr5_+_115298165 0.197 ENST00000357872.4
AQPEP
Aminopeptidase Q
chr1_+_109792641 0.195 ENST00000271332.3
CELSR2
cadherin, EGF LAG seven-pass G-type receptor 2
chr7_+_4721885 0.195 ENST00000328914.4
FOXK1
forkhead box K1
chr1_+_22889953 0.194 ENST00000374644.4
ENST00000166244.3
ENST00000538803.1
EPHA8


EPH receptor A8


chr1_-_40237020 0.194 ENST00000327582.5
OXCT2
3-oxoacid CoA transferase 2
chr15_+_63340858 0.194 ENST00000560615.1
TPM1
tropomyosin 1 (alpha)
chrX_+_72223352 0.193 ENST00000373521.2
ENST00000538388.1
PABPC1L2B

poly(A) binding protein, cytoplasmic 1-like 2B

chr7_-_50132801 0.192 ENST00000419417.1
ZPBP
zona pellucida binding protein
chr1_-_11865982 0.191 ENST00000418034.1
MTHFR
methylenetetrahydrofolate reductase (NAD(P)H)
chr8_+_73449625 0.190 ENST00000523207.1
KCNB2
potassium voltage-gated channel, Shab-related subfamily, member 2
chr2_+_24346324 0.190 ENST00000407625.1
ENST00000420135.2
FAM228B

family with sequence similarity 228, member B

chr7_-_50132860 0.190 ENST00000046087.2
ZPBP
zona pellucida binding protein
chr19_-_15090488 0.190 ENST00000594383.1
ENST00000598504.1
ENST00000597262.1
SLC1A6


solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6


chr7_-_1199781 0.190 ENST00000397083.1
ENST00000401903.1
ENST00000316495.3
ZFAND2A


zinc finger, AN1-type domain 2A


chr8_-_22014255 0.189 ENST00000424267.2
LGI3
leucine-rich repeat LGI family, member 3
chr22_-_50689786 0.188 ENST00000216271.5
HDAC10
histone deacetylase 10
chr19_+_45844032 0.187 ENST00000589837.1
KLC3
kinesin light chain 3
chr9_+_135037334 0.187 ENST00000393229.3
ENST00000360670.3
ENST00000393228.4
ENST00000372179.3
NTNG2



netrin G2



chr15_-_70388943 0.186 ENST00000559048.1
ENST00000560939.1
ENST00000440567.3
ENST00000557907.1
ENST00000558379.1
ENST00000451782.2
ENST00000559929.1
TLE3






transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila)






chr17_-_64187973 0.185 ENST00000583358.1
ENST00000392769.2
CEP112

centrosomal protein 112kDa


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0021966 corticospinal neuron axon guidance(GO:0021966)
0.2 0.3 GO:0071812 regulation of fever generation by regulation of prostaglandin secretion(GO:0071810) positive regulation of fever generation by positive regulation of prostaglandin secretion(GO:0071812) positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling(GO:0071848) regulation of fever generation by prostaglandin secretion(GO:0100009)
0.2 1.4 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.2 0.5 GO:0045062 extrathymic T cell selection(GO:0045062)
0.1 0.6 GO:0032811 negative regulation of epinephrine secretion(GO:0032811) epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway(GO:0035625)
0.1 0.7 GO:0032455 nerve growth factor processing(GO:0032455)
0.1 0.9 GO:0060992 response to fungicide(GO:0060992)
0.1 0.5 GO:0071469 detection of mechanical stimulus involved in sensory perception of touch(GO:0050976) cellular response to alkaline pH(GO:0071469)
0.1 1.1 GO:2001300 lipoxin metabolic process(GO:2001300)
0.1 0.3 GO:0043397 corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397)
0.1 0.9 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
0.1 0.3 GO:0044771 meiotic cell cycle phase transition(GO:0044771) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.1 0.3 GO:0009405 pathogenesis(GO:0009405)
0.1 0.8 GO:0060160 negative regulation of dopamine receptor signaling pathway(GO:0060160)
0.1 0.8 GO:0060179 male mating behavior(GO:0060179)
0.1 0.5 GO:0007070 negative regulation of transcription during mitosis(GO:0007068) negative regulation of transcription from RNA polymerase II promoter during mitosis(GO:0007070)
0.1 0.3 GO:0006667 sphinganine metabolic process(GO:0006667)
0.1 0.3 GO:0003192 mitral valve formation(GO:0003192)
0.1 0.3 GO:0045226 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.1 0.2 GO:0003162 atrioventricular node development(GO:0003162)
0.1 0.3 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.1 0.4 GO:0021834 chemorepulsion involved in embryonic olfactory bulb interneuron precursor migration(GO:0021834)
0.1 0.3 GO:1902460 regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
0.1 0.3 GO:2000230 negative regulation of pancreatic stellate cell proliferation(GO:2000230)
0.1 0.9 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.1 0.8 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.1 0.2 GO:1904933 regulation of cell proliferation in midbrain(GO:1904933)
0.1 0.2 GO:0035623 regulation of pronephros size(GO:0035565) renal glucose absorption(GO:0035623)
0.1 0.3 GO:0007509 mesoderm migration involved in gastrulation(GO:0007509)
0.1 0.3 GO:0001188 RNA polymerase I transcriptional preinitiation complex assembly(GO:0001188) RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript(GO:0001189)
0.1 0.2 GO:1903697 negative regulation of microvillus assembly(GO:1903697)
0.1 0.6 GO:0071494 cellular response to UV-C(GO:0071494)
0.1 0.2 GO:1900126 negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.1 0.2 GO:1904106 protein localization to microvillus(GO:1904106)
0.1 0.3 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.1 0.2 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.1 0.4 GO:0038031 non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.1 0.3 GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.1 0.3 GO:0032687 negative regulation of interferon-alpha production(GO:0032687)
0.1 0.5 GO:1903764 regulation of potassium ion export across plasma membrane(GO:1903764)
0.1 0.7 GO:0098887 neurotransmitter receptor transport, endosome to postsynaptic membrane(GO:0098887)
0.1 0.1 GO:1905244 regulation of modification of synaptic structure(GO:1905244)
0.1 0.3 GO:0071477 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.1 0.2 GO:0000255 allantoin metabolic process(GO:0000255)
0.1 0.5 GO:0046836 glycolipid transport(GO:0046836)
0.1 0.4 GO:0061052 negative regulation of cell growth involved in cardiac muscle cell development(GO:0061052)
0.1 0.3 GO:0030035 microspike assembly(GO:0030035)
0.1 0.1 GO:0061341 non-canonical Wnt signaling pathway involved in heart development(GO:0061341) planar cell polarity pathway involved in heart morphogenesis(GO:0061346)
0.1 0.3 GO:0048073 regulation of eye pigmentation(GO:0048073)
0.1 0.3 GO:0038169 somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
0.1 0.2 GO:0017186 peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase(GO:0017186)
0.1 0.1 GO:0051930 regulation of sensory perception of pain(GO:0051930) regulation of sensory perception(GO:0051931)
0.1 0.5 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.1 0.2 GO:0042700 luteinizing hormone signaling pathway(GO:0042700) cellular response to luteinizing hormone stimulus(GO:0071373)
0.1 0.2 GO:0071109 superior temporal gyrus development(GO:0071109)
0.1 0.5 GO:0060020 Bergmann glial cell differentiation(GO:0060020)
0.1 0.2 GO:0003219 cardiac right ventricle formation(GO:0003219)
0.1 0.2 GO:0045994 positive regulation of translational initiation by iron(GO:0045994)
0.1 0.2 GO:0060178 regulation of exocyst assembly(GO:0001928) regulation of exocyst localization(GO:0060178)
0.0 0.3 GO:0098535 de novo centriole assembly(GO:0098535)
0.0 0.1 GO:1900073 regulation of neuromuscular synaptic transmission(GO:1900073) positive regulation of neuromuscular synaptic transmission(GO:1900075)
0.0 0.1 GO:0006566 threonine metabolic process(GO:0006566)
0.0 0.3 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.0 0.1 GO:0007439 ectodermal digestive tract development(GO:0007439) embryonic ectodermal digestive tract development(GO:0048611) right lung development(GO:0060458)
0.0 0.0 GO:0006303 double-strand break repair via nonhomologous end joining(GO:0006303)
0.0 0.7 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.0 0.1 GO:0030327 prenylated protein catabolic process(GO:0030327)
0.0 0.1 GO:1903984 positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.0 0.4 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 0.1 GO:0035408 histone H3-T6 phosphorylation(GO:0035408)
0.0 0.1 GO:1902490 regulation of sperm capacitation(GO:1902490)
0.0 0.4 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.0 0.1 GO:2001037 tongue muscle cell differentiation(GO:0035981) positive regulation of skeletal muscle fiber differentiation(GO:1902811) regulation of tongue muscle cell differentiation(GO:2001035) positive regulation of tongue muscle cell differentiation(GO:2001037)
0.0 0.1 GO:0021919 BMP signaling pathway involved in spinal cord dorsal/ventral patterning(GO:0021919)
0.0 0.1 GO:1900369 transcription, RNA-templated(GO:0001172) negative regulation of RNA interference(GO:1900369)
0.0 0.2 GO:0007386 compartment pattern specification(GO:0007386)
0.0 0.1 GO:0072720 cellular response to mycotoxin(GO:0036146) response to dithiothreitol(GO:0072720)
0.0 0.1 GO:0060931 sinoatrial node cell development(GO:0060931)
0.0 0.2 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.0 0.3 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.0 0.1 GO:0003415 chondrocyte hypertrophy(GO:0003415)
0.0 0.2 GO:0043323 regulation of natural killer cell degranulation(GO:0043321) positive regulation of natural killer cell degranulation(GO:0043323)
0.0 0.1 GO:0038162 erythropoietin-mediated signaling pathway(GO:0038162)
0.0 0.2 GO:0033274 response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
0.0 0.1 GO:0021957 corticospinal tract morphogenesis(GO:0021957)
0.0 0.5 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.2 GO:1905123 regulation of glucosylceramidase activity(GO:1905123)
0.0 0.2 GO:2000170 positive regulation of peptidyl-cysteine S-nitrosylation(GO:2000170)
0.0 0.2 GO:0046952 ketone body catabolic process(GO:0046952)
0.0 0.2 GO:0086048 membrane depolarization during bundle of His cell action potential(GO:0086048)
0.0 0.4 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.0 0.1 GO:1904808 regulation of protein oxidation(GO:1904806) positive regulation of protein oxidation(GO:1904808)
0.0 0.1 GO:0060024 rhythmic synaptic transmission(GO:0060024)
0.0 0.1 GO:0048016 inositol phosphate-mediated signaling(GO:0048016)
0.0 0.2 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.0 0.1 GO:0032484 Ral protein signal transduction(GO:0032484) regulation of Ral protein signal transduction(GO:0032485)
0.0 0.1 GO:2000466 negative regulation of glycogen (starch) synthase activity(GO:2000466) regulation of renal water transport(GO:2001151) positive regulation of renal water transport(GO:2001153)
0.0 0.2 GO:0060214 endocardium formation(GO:0060214)
0.0 0.1 GO:1902613 regulation of anti-Mullerian hormone signaling pathway(GO:1902612) negative regulation of anti-Mullerian hormone signaling pathway(GO:1902613) anti-Mullerian hormone signaling pathway(GO:1990262)
0.0 0.2 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0 0.1 GO:1900248 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
0.0 0.1 GO:0014022 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.0 0.2 GO:0072069 DCT cell differentiation(GO:0072069) metanephric DCT cell differentiation(GO:0072240)
0.0 0.1 GO:0061289 cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204)
0.0 0.1 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.0 0.2 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.0 0.1 GO:0072205 metanephric collecting duct development(GO:0072205)
0.0 0.3 GO:0042670 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0 0.2 GO:0006102 isocitrate metabolic process(GO:0006102)
0.0 0.1 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.0 0.4 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.1 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.0 0.1 GO:2000672 regulation of motor neuron apoptotic process(GO:2000671) negative regulation of motor neuron apoptotic process(GO:2000672)
0.0 0.2 GO:0050915 sensory perception of sour taste(GO:0050915)
0.0 0.1 GO:0010216 maintenance of DNA methylation(GO:0010216) positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.0 0.1 GO:0003416 endochondral bone growth(GO:0003416) bone growth(GO:0098868)
0.0 0.0 GO:0007497 posterior midgut development(GO:0007497)
0.0 0.1 GO:1904397 negative regulation of neuromuscular junction development(GO:1904397)
0.0 0.1 GO:0009447 putrescine catabolic process(GO:0009447)
0.0 0.1 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.0 0.1 GO:0018243 protein O-linked glycosylation via threonine(GO:0018243)
0.0 0.2 GO:0072602 interleukin-4 secretion(GO:0072602)
0.0 0.2 GO:0070778 L-aspartate transport(GO:0070778) L-aspartate transmembrane transport(GO:0089712)
0.0 0.3 GO:0021999 neural plate anterior/posterior regionalization(GO:0021999)
0.0 0.2 GO:0034441 plasma lipoprotein particle oxidation(GO:0034441)
0.0 0.1 GO:1990927 short-term synaptic potentiation(GO:1990926) calcium ion regulated lysosome exocytosis(GO:1990927)
0.0 0.1 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.0 0.2 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.0 0.1 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.0 0.3 GO:0048843 negative regulation of axon extension involved in axon guidance(GO:0048843)
0.0 0.0 GO:0071321 cellular response to cGMP(GO:0071321)
0.0 0.1 GO:0048278 vesicle docking(GO:0048278)
0.0 0.1 GO:0003308 regulation of Wnt signaling pathway involved in heart development(GO:0003307) negative regulation of Wnt signaling pathway involved in heart development(GO:0003308)
0.0 0.2 GO:0038180 nerve growth factor signaling pathway(GO:0038180)
0.0 0.1 GO:0045217 cell-cell junction maintenance(GO:0045217) zonula adherens maintenance(GO:0045218)
0.0 0.6 GO:1901897 regulation of relaxation of cardiac muscle(GO:1901897)
0.0 0.3 GO:0051964 negative regulation of synapse assembly(GO:0051964)
0.0 0.2 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
0.0 0.6 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.1 GO:1905167 positive regulation of lysosomal protein catabolic process(GO:1905167)
0.0 0.1 GO:0007406 negative regulation of neuroblast proliferation(GO:0007406)
0.0 0.1 GO:0018101 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.0 0.0 GO:0072061 inner medullary collecting duct development(GO:0072061)
0.0 0.2 GO:1904179 positive regulation of adipose tissue development(GO:1904179)
0.0 0.2 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.0 0.1 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
0.0 0.1 GO:1904956 planar cell polarity pathway involved in axis elongation(GO:0003402) convergent extension involved in axis elongation(GO:0060028) regulation of midbrain dopaminergic neuron differentiation(GO:1904956) regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000053)
0.0 0.1 GO:0014807 regulation of somitogenesis(GO:0014807)
0.0 0.1 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.0 0.2 GO:0071286 cellular response to magnesium ion(GO:0071286)
0.0 0.1 GO:0038098 sequestering of BMP from receptor via BMP binding(GO:0038098)
0.0 0.1 GO:0015920 lipopolysaccharide transport(GO:0015920)
0.0 0.1 GO:0097089 methyl-branched fatty acid metabolic process(GO:0097089)
0.0 0.2 GO:0060754 positive regulation of mast cell chemotaxis(GO:0060754)
0.0 0.3 GO:0032494 response to peptidoglycan(GO:0032494)
0.0 0.1 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563) negative regulation of response to alcohol(GO:1901420)
0.0 0.1 GO:0006597 spermine biosynthetic process(GO:0006597)
0.0 0.2 GO:0043615 astrocyte cell migration(GO:0043615)
0.0 0.1 GO:0045897 positive regulation of transcription during mitosis(GO:0045897)
0.0 0.0 GO:1901185 negative regulation of ERBB signaling pathway(GO:1901185)
0.0 0.2 GO:1900107 regulation of nodal signaling pathway(GO:1900107)
0.0 0.1 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
0.0 0.2 GO:0043385 mycotoxin metabolic process(GO:0043385) aflatoxin metabolic process(GO:0046222) organic heteropentacyclic compound metabolic process(GO:1901376)
0.0 0.1 GO:0008340 determination of adult lifespan(GO:0008340)
0.0 0.2 GO:0070307 lens fiber cell development(GO:0070307)
0.0 0.1 GO:0016999 antibiotic metabolic process(GO:0016999) cellular amide catabolic process(GO:0043605)
0.0 0.0 GO:0032911 negative regulation of transforming growth factor beta1 production(GO:0032911)
0.0 0.2 GO:0035815 positive regulation of renal sodium excretion(GO:0035815)
0.0 0.1 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.0 0.6 GO:0070306 lens fiber cell differentiation(GO:0070306)
0.0 0.3 GO:1903012 positive regulation of bone development(GO:1903012)
0.0 0.2 GO:0060363 cranial suture morphogenesis(GO:0060363)
0.0 0.0 GO:0061535 glutamate secretion, neurotransmission(GO:0061535)
0.0 0.4 GO:0009650 UV protection(GO:0009650)
0.0 0.2 GO:1904322 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.0 0.4 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.1 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.0 0.1 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.0 0.1 GO:1904204 skeletal muscle hypertrophy(GO:0014734) regulation of skeletal muscle hypertrophy(GO:1904204)
0.0 0.1 GO:0099540 synaptic signaling via neuropeptide(GO:0099538) trans-synaptic signaling by neuropeptide(GO:0099540) trans-synaptic signaling by neuropeptide, modulating synaptic transmission(GO:0099551)
0.0 0.2 GO:0042756 drinking behavior(GO:0042756)
0.0 0.1 GO:1901856 negative regulation of cellular respiration(GO:1901856)
0.0 0.1 GO:0051685 maintenance of ER location(GO:0051685)
0.0 0.2 GO:0032431 activation of phospholipase A2 activity(GO:0032431)
0.0 0.1 GO:1903028 positive regulation of opsonization(GO:1903028)
0.0 0.1 GO:0097187 dentinogenesis(GO:0097187)
0.0 0.1 GO:0006210 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) beta-alanine metabolic process(GO:0019482) thymine metabolic process(GO:0019859) uracil metabolic process(GO:0019860)
0.0 0.1 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
0.0 0.1 GO:0003331 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331) negative regulation of fibroblast growth factor production(GO:0090272)
0.0 0.2 GO:0014041 regulation of neuron maturation(GO:0014041)
0.0 0.1 GO:0048250 mitochondrial iron ion transport(GO:0048250)
0.0 0.1 GO:0046833 positive regulation of RNA export from nucleus(GO:0046833)
0.0 0.3 GO:0071318 cellular response to ATP(GO:0071318)
0.0 0.1 GO:0072364 regulation of cellular ketone metabolic process by regulation of transcription from RNA polymerase II promoter(GO:0072364)
0.0 0.1 GO:0034285 response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.0 0.1 GO:0010641 positive regulation of platelet-derived growth factor receptor signaling pathway(GO:0010641)
0.0 0.6 GO:0070932 histone H3 deacetylation(GO:0070932)
0.0 0.3 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 0.1 GO:0070197 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.0 0.0 GO:0002384 hepatic immune response(GO:0002384)
0.0 0.2 GO:0034465 response to carbon monoxide(GO:0034465) smooth muscle contraction involved in micturition(GO:0060083)
0.0 0.1 GO:0060166 olfactory pit development(GO:0060166)
0.0 0.1 GO:0010957 negative regulation of vitamin D biosynthetic process(GO:0010957)
0.0 0.2 GO:0090481 pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.0 0.0 GO:0035283 rhombomere 3 development(GO:0021569) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.0 0.2 GO:0016322 neuron remodeling(GO:0016322)
0.0 0.0 GO:0007440 foregut morphogenesis(GO:0007440) embryonic foregut morphogenesis(GO:0048617)
0.0 0.0 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.1 GO:0045650 negative regulation of macrophage differentiation(GO:0045650)
0.0 0.1 GO:0070427 nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.0 0.1 GO:0032972 regulation of muscle filament sliding speed(GO:0032972)
0.0 0.1 GO:0086073 bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.0 0.1 GO:1902255 positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902255)
0.0 0.0 GO:0032289 central nervous system myelin formation(GO:0032289)
0.0 0.0 GO:0098886 modification of dendritic spine(GO:0098886)
0.0 0.1 GO:0097411 hypoxia-inducible factor-1alpha signaling pathway(GO:0097411)
0.0 0.4 GO:0039702 viral budding via host ESCRT complex(GO:0039702)
0.0 0.0 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560)
0.0 0.0 GO:0070407 oxidation-dependent protein catabolic process(GO:0070407)
0.0 0.4 GO:0071243 cellular response to arsenic-containing substance(GO:0071243)
0.0 0.1 GO:0071963 establishment or maintenance of cell polarity regulating cell shape(GO:0071963)
0.0 0.1 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.0 0.1 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 0.1 GO:0002934 desmosome organization(GO:0002934)
0.0 0.1 GO:0006196 AMP catabolic process(GO:0006196)
0.0 0.3 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.0 0.0 GO:1900454 positive regulation of long term synaptic depression(GO:1900454) regulation of spontaneous neurotransmitter secretion(GO:1904048)
0.0 0.1 GO:0097369 sodium ion import(GO:0097369)
0.0 0.2 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.0 0.0 GO:0006579 amino-acid betaine catabolic process(GO:0006579)
0.0 0.1 GO:0071502 cellular response to temperature stimulus(GO:0071502)
0.0 0.1 GO:2000110 negative regulation of macrophage apoptotic process(GO:2000110)
0.0 0.4 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.0 0.1 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.0 0.1 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.2 GO:2000178 negative regulation of neural precursor cell proliferation(GO:2000178)
0.0 0.3 GO:0060285 cilium-dependent cell motility(GO:0060285)
0.0 0.0 GO:0023041 neuronal signal transduction(GO:0023041)
0.0 0.3 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.5 GO:0097503 sialylation(GO:0097503)
0.0 0.1 GO:0016240 autophagosome docking(GO:0016240)
0.0 0.1 GO:0070544 histone H3-K36 demethylation(GO:0070544)
0.0 0.1 GO:0000066 mitochondrial ornithine transport(GO:0000066)
0.0 0.1 GO:0006537 glutamate biosynthetic process(GO:0006537)
0.0 0.0 GO:1904098 regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
0.0 0.1 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.0 0.1 GO:0097021 Peyer's patch morphogenesis(GO:0061146) lymphocyte migration into lymphoid organs(GO:0097021)
0.0 0.1 GO:0010157 response to chlorate(GO:0010157)
0.0 0.1 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.0 0.1 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.0 0.4 GO:0046627 negative regulation of insulin receptor signaling pathway(GO:0046627)
0.0 0.1 GO:0048733 sebaceous gland development(GO:0048733)
0.0 0.2 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.3 GO:0072661 protein targeting to plasma membrane(GO:0072661)
0.0 0.2 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.0 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.0 0.1 GO:0032957 inositol trisphosphate metabolic process(GO:0032957)
0.0 0.0 GO:1900122 positive regulation of receptor binding(GO:1900122)
0.0 0.1 GO:0002329 pre-B cell differentiation(GO:0002329)
0.0 0.1 GO:0090394 negative regulation of excitatory postsynaptic potential(GO:0090394)
0.0 0.3 GO:0010642 negative regulation of platelet-derived growth factor receptor signaling pathway(GO:0010642)
0.0 0.0 GO:1902303 negative regulation of potassium ion export(GO:1902303)
0.0 0.2 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.0 GO:0010040 response to iron(II) ion(GO:0010040)
0.0 0.1 GO:0061339 establishment of monopolar cell polarity(GO:0061162) establishment or maintenance of monopolar cell polarity(GO:0061339)
0.0 0.1 GO:0007296 vitellogenesis(GO:0007296)
0.0 0.0 GO:0007215 glutamate receptor signaling pathway(GO:0007215)
0.0 0.0 GO:0048631 regulation of skeletal muscle tissue growth(GO:0048631)
0.0 0.1 GO:0006228 UTP biosynthetic process(GO:0006228)
0.0 0.0 GO:0030225 macrophage differentiation(GO:0030225)
0.0 0.1 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.1 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.2 GO:0097264 self proteolysis(GO:0097264)
0.0 0.1 GO:0006090 pyruvate metabolic process(GO:0006090)
0.0 0.0 GO:1903626 positive regulation of apoptotic DNA fragmentation(GO:1902512) positive regulation of DNA catabolic process(GO:1903626)
0.0 0.1 GO:1903756 regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
0.0 0.2 GO:0051601 exocyst localization(GO:0051601)
0.0 0.1 GO:0005980 polysaccharide catabolic process(GO:0000272) glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.0 0.1 GO:0060022 hard palate development(GO:0060022)
0.0 0.5 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.0 0.1 GO:0051684 maintenance of Golgi location(GO:0051684)
0.0 0.6 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.2 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.0 0.1 GO:0032286 central nervous system myelin maintenance(GO:0032286)
0.0 0.2 GO:0001829 trophectodermal cell differentiation(GO:0001829)
0.0 0.0 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.0 0.0 GO:0060340 positive regulation of type I interferon-mediated signaling pathway(GO:0060340)
0.0 0.0 GO:0097010 eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.0 0.0 GO:1904016 response to Thyroglobulin triiodothyronine(GO:1904016)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0031251 PAN complex(GO:0031251)
0.1 0.4 GO:0030936 collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
0.1 1.0 GO:0070852 cell body fiber(GO:0070852)
0.1 0.7 GO:0005587 collagen type IV trimer(GO:0005587)
0.1 0.8 GO:0098845 postsynaptic endosome(GO:0098845)
0.1 0.1 GO:0098645 network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.1 0.2 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.1 0.2 GO:0098855 HCN channel complex(GO:0098855)
0.1 1.0 GO:0031209 SCAR complex(GO:0031209)
0.1 0.2 GO:0045160 myosin I complex(GO:0045160)
0.0 0.3 GO:0032437 cuticular plate(GO:0032437)
0.0 0.9 GO:0005862 muscle thin filament tropomyosin(GO:0005862) bleb(GO:0032059)
0.0 0.1 GO:0031379 RNA-directed RNA polymerase complex(GO:0031379)
0.0 0.5 GO:0043219 lateral loop(GO:0043219)
0.0 0.4 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 0.7 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.1 GO:0043224 nuclear SCF ubiquitin ligase complex(GO:0043224)
0.0 0.5 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.3 GO:0042587 glycogen granule(GO:0042587)
0.0 0.4 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.1 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.0 1.0 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.2 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.1 GO:0044308 axonal spine(GO:0044308)
0.0 0.2 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.0 0.7 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 0.2 GO:0005610 laminin-5 complex(GO:0005610)
0.0 0.1 GO:0005960 glycine cleavage complex(GO:0005960)
0.0 0.9 GO:0002080 acrosomal membrane(GO:0002080)
0.0 0.1 GO:0099568 cytoplasmic region(GO:0099568)
0.0 0.3 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.3 GO:0099634 postsynaptic specialization membrane(GO:0099634)
0.0 0.1 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.0 0.3 GO:0033010 paranodal junction(GO:0033010)
0.0 0.0 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 0.1 GO:0031417 NatC complex(GO:0031417)
0.0 0.1 GO:0071565 nBAF complex(GO:0071565)
0.0 0.2 GO:0032010 phagolysosome(GO:0032010)
0.0 0.0 GO:0061689 tricellular tight junction(GO:0061689)
0.0 0.6 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.1 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.0 0.1 GO:1903349 omegasome membrane(GO:1903349)
0.0 0.4 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.3 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.0 GO:0097444 spine apparatus(GO:0097444)
0.0 0.3 GO:0005858 axonemal dynein complex(GO:0005858)
0.0 2.1 GO:0034705 potassium channel complex(GO:0034705)
0.0 0.3 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.1 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.0 0.3 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.2 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.8 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.1 GO:0005784 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0 1.7 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 0.1 GO:1990909 Wnt signalosome(GO:1990909)
0.0 0.4 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 0.3 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.1 GO:0020018 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.0 0.1 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.0 0.0 GO:0055087 Ski complex(GO:0055087)
0.0 0.4 GO:0000145 exocyst(GO:0000145)
0.0 0.6 GO:0005874 microtubule(GO:0005874)
0.0 0.2 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.2 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.4 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.1 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.0 0.2 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.0 0.3 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.0 GO:0044326 dendritic spine neck(GO:0044326)
0.0 0.1 GO:1990584 cardiac Troponin complex(GO:1990584)
0.0 0.6 GO:0098878 ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)
0.0 0.1 GO:0098797 plasma membrane protein complex(GO:0098797)
0.0 0.0 GO:0016589 NURF complex(GO:0016589)
0.0 0.1 GO:0005683 U7 snRNP(GO:0005683)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0016404 15-hydroxyprostaglandin dehydrogenase (NAD+) activity(GO:0016404)
0.2 1.0 GO:0047751 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765) cholestenone 5-alpha-reductase activity(GO:0047751)
0.2 0.7 GO:0086062 voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
0.2 0.6 GO:0016838 carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.2 0.6 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
0.2 0.5 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.2 0.5 GO:0098782 mechanically-gated potassium channel activity(GO:0098782)
0.1 0.7 GO:0031750 D3 dopamine receptor binding(GO:0031750)
0.1 1.1 GO:0008420 CTD phosphatase activity(GO:0008420)
0.1 0.9 GO:0032051 clathrin light chain binding(GO:0032051)
0.1 0.8 GO:0043426 MRF binding(GO:0043426)
0.1 0.3 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
0.1 0.6 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.1 0.3 GO:0061769 ribosylnicotinamide kinase activity(GO:0050262) ribosylnicotinate kinase activity(GO:0061769)
0.1 0.3 GO:0017089 glycolipid transporter activity(GO:0017089)
0.1 0.2 GO:0050254 rhodopsin kinase activity(GO:0050254)
0.1 0.3 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.1 0.3 GO:0002054 nucleobase binding(GO:0002054)
0.1 0.2 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.1 0.2 GO:0017130 poly(C) RNA binding(GO:0017130)
0.1 0.2 GO:0048763 calcium-induced calcium release activity(GO:0048763)
0.1 0.3 GO:0047288 monosialoganglioside sialyltransferase activity(GO:0047288)
0.1 0.4 GO:0004522 ribonuclease A activity(GO:0004522)
0.1 0.3 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.1 1.4 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 0.4 GO:0070097 delta-catenin binding(GO:0070097)
0.1 0.5 GO:0050692 DBD domain binding(GO:0050692)
0.1 0.3 GO:0004994 somatostatin receptor activity(GO:0004994)
0.1 0.2 GO:0016603 glutaminyl-peptide cyclotransferase activity(GO:0016603)
0.1 0.4 GO:1990254 keratin filament binding(GO:1990254)
0.1 0.2 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.1 0.3 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.0 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.0 0.5 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.2 GO:0008410 CoA-transferase activity(GO:0008410)
0.0 0.2 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.0 0.4 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.1 GO:0035403 histone kinase activity (H3-T6 specific)(GO:0035403)
0.0 0.4 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.0 0.1 GO:0004103 choline kinase activity(GO:0004103)
0.0 0.2 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0 0.2 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.0 0.2 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.0 0.2 GO:0016402 pristanoyl-CoA oxidase activity(GO:0016402)
0.0 0.1 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.0 0.1 GO:0003968 RNA-directed RNA polymerase activity(GO:0003968)
0.0 0.2 GO:0010465 nerve growth factor receptor activity(GO:0010465)
0.0 0.1 GO:0004174 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.0 0.2 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.2 GO:0004963 follicle-stimulating hormone receptor activity(GO:0004963)
0.0 0.3 GO:0070573 metallodipeptidase activity(GO:0070573)
0.0 0.5 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0 0.2 GO:0051765 inositol tetrakisphosphate kinase activity(GO:0051765)
0.0 0.2 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.0 0.2 GO:0016520 growth hormone-releasing hormone receptor activity(GO:0016520)
0.0 0.4 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.2 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.1 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.0 0.1 GO:0016418 S-acetyltransferase activity(GO:0016418)
0.0 0.2 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.0 0.1 GO:0004362 glutathione-disulfide reductase activity(GO:0004362)
0.0 1.5 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.2 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.0 0.3 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 0.1 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 0.4 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.0 0.6 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.2 GO:0017018 myosin phosphatase activity(GO:0017018)
0.0 0.3 GO:0086007 voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007)
0.0 0.5 GO:0030957 Tat protein binding(GO:0030957)
0.0 1.0 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.3 GO:0010385 double-stranded methylated DNA binding(GO:0010385)
0.0 0.3 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.2 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.0 0.8 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.2 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.0 0.2 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 0.1 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 0.1 GO:0004487 methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
0.0 0.1 GO:0032184 SUMO polymer binding(GO:0032184)
0.0 0.3 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.3 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.0 0.1 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.0 0.0 GO:0047760 butyrate-CoA ligase activity(GO:0047760)
0.0 0.1 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.0 0.1 GO:0002114 interleukin-33 receptor activity(GO:0002114)
0.0 0.1 GO:0004832 valine-tRNA ligase activity(GO:0004832)
0.0 0.1 GO:0070506 high-density lipoprotein particle receptor activity(GO:0070506)
0.0 0.5 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 0.1 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.1 GO:0042577 lipid phosphatase activity(GO:0042577)
0.0 0.3 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.1 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739)
0.0 0.1 GO:0071209 U7 snRNA binding(GO:0071209)
0.0 0.2 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.0 0.1 GO:0046592 polyamine oxidase activity(GO:0046592) spermine:oxygen oxidoreductase (spermidine-forming) activity(GO:0052901)
0.0 0.5 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.3 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723)
0.0 0.1 GO:0015439 heme-transporting ATPase activity(GO:0015439)
0.0 0.2 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.0 0.1 GO:0033149 FFAT motif binding(GO:0033149)
0.0 0.2 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.0 0.1 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 0.1 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.0 0.1 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 0.1 GO:0030226 apolipoprotein receptor activity(GO:0030226) lipoprotein transporter activity(GO:0042954)
0.0 0.1 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.0 0.2 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 0.2 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 0.1 GO:0060175 brain-derived neurotrophic factor-activated receptor activity(GO:0060175)
0.0 0.1 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.0 0.1 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.0 0.1 GO:0051022 GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022)
0.0 0.4 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 0.1 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0 0.4 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.1 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
0.0 0.2 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.0 GO:0019981 interleukin-6 receptor activity(GO:0004915) interleukin-6 binding(GO:0019981)
0.0 0.1 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.0 0.1 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.0 0.2 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.2 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0 0.0 GO:0070361 mitochondrial light strand promoter anti-sense binding(GO:0070361) mitochondrial heavy strand promoter anti-sense binding(GO:0070362) mitochondrial heavy strand promoter sense binding(GO:0070364)
0.0 0.1 GO:0043237 laminin-1 binding(GO:0043237)
0.0 0.1 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.0 0.2 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.0 0.3 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.1 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0 0.1 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.1 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.0 GO:0004629 phospholipase C activity(GO:0004629)
0.0 0.2 GO:0031386 protein tag(GO:0031386)
0.0 0.3 GO:0001054 RNA polymerase I activity(GO:0001054)
0.0 0.1 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.1 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.0 GO:0004662 CAAX-protein geranylgeranyltransferase activity(GO:0004662)
0.0 0.0 GO:0050613 delta14-sterol reductase activity(GO:0050613)
0.0 0.1 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.0 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.0 0.1 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.0 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.0 0.3 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.5 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.1 GO:1990948 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.0 0.1 GO:0003996 acyl-CoA ligase activity(GO:0003996)
0.0 0.1 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.1 GO:0003998 acylphosphatase activity(GO:0003998)
0.0 0.0 GO:0004448 isocitrate dehydrogenase activity(GO:0004448)
0.0 0.1 GO:0042835 BRE binding(GO:0042835)
0.0 0.2 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.0 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.0 0.2 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.3 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.6 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.1 GO:0004920 interleukin-10 receptor activity(GO:0004920)
0.0 0.2 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.0 GO:0004980 melanocyte-stimulating hormone receptor activity(GO:0004980)
0.0 0.4 GO:0045503 dynein light chain binding(GO:0045503)
0.0 0.1 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.1 GO:0050733 RS domain binding(GO:0050733)
0.0 0.2 GO:0005542 folic acid binding(GO:0005542)
0.0 0.1 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0 0.1 GO:0089720 caspase binding(GO:0089720)
0.0 0.4 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.1 GO:0042731 PH domain binding(GO:0042731)
0.0 0.1 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.0 0.1 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 0.0 GO:0034057 RNA strand-exchange activity(GO:0034057)
0.0 0.0 GO:0010861 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 PID_EPHA2_FWD_PATHWAY EPHA2 forward signaling
0.0 0.6 PID_S1P_S1P4_PATHWAY S1P4 pathway
0.0 1.7 NABA_BASEMENT_MEMBRANES Genes encoding structural components of basement membranes
0.0 0.5 PID_ERB_GENOMIC_PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.1 PID_S1P_S1P2_PATHWAY S1P2 pathway
0.0 0.3 PID_TCR_RAS_PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.8 PID_RXR_VDR_PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.6 NABA_COLLAGENS Genes encoding collagen proteins
0.0 0.7 ST_WNT_BETA_CATENIN_PATHWAY Wnt/beta-catenin Pathway
0.0 0.8 PID_ECADHERIN_NASCENT_AJ_PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 1.1 PID_AJDISS_2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.5 ST_WNT_CA2_CYCLIC_GMP_PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 0.5 PID_EPHA_FWDPATHWAY EPHA forward signaling
0.0 0.3 SA_B_CELL_RECEPTOR_COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 0.2 PID_IL5_PATHWAY IL5-mediated signaling events
0.0 0.0 PID_S1P_S1P3_PATHWAY S1P3 pathway
0.0 0.6 PID_INSULIN_PATHWAY Insulin Pathway
0.0 0.5 PID_RET_PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.1 PID_VEGFR1_PATHWAY VEGFR1 specific signals
0.0 0.1 PID_ECADHERIN_KERATINOCYTE_PATHWAY E-cadherin signaling in keratinocytes
0.0 0.3 PID_INTEGRIN_A9B1_PATHWAY Alpha9 beta1 integrin signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 REACTOME_ANDROGEN_BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.1 1.4 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 1.0 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.4 REACTOME_MEMBRANE_BINDING_AND_TARGETTING_OF_GAG_PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 1.0 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.1 REACTOME_SIGNALING_BY_EGFR_IN_CANCER Genes involved in Signaling by EGFR in Cancer
0.0 0.5 REACTOME_ABCA_TRANSPORTERS_IN_LIPID_HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 1.5 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.0 1.4 REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.6 REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 1.2 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.0 1.3 REACTOME_STRIATED_MUSCLE_CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.3 REACTOME_CIRCADIAN_CLOCK Genes involved in Circadian Clock
0.0 0.3 REACTOME_SIGNAL_ATTENUATION Genes involved in Signal attenuation
0.0 0.7 REACTOME_CGMP_EFFECTS Genes involved in cGMP effects
0.0 0.1 REACTOME_IRAK1_RECRUITS_IKK_COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 0.3 REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.0 REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.3 REACTOME_ALPHA_LINOLENIC_ACID_ALA_METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.2 REACTOME_RAS_ACTIVATION_UOPN_CA2_INFUX_THROUGH_NMDA_RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0 0.3 REACTOME_IL_7_SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.2 REACTOME_SPRY_REGULATION_OF_FGF_SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.2 REACTOME_ADENYLATE_CYCLASE_ACTIVATING_PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.5 REACTOME_KINESINS Genes involved in Kinesins
0.0 0.3 REACTOME_HYALURONAN_METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.2 REACTOME_TIE2_SIGNALING Genes involved in Tie2 Signaling
0.0 0.2 REACTOME_INTRINSIC_PATHWAY Genes involved in Intrinsic Pathway
0.0 0.3 REACTOME_GRB2_SOS_PROVIDES_LINKAGE_TO_MAPK_SIGNALING_FOR_INTERGRINS_ Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 0.6 REACTOME_GAB1_SIGNALOSOME Genes involved in GAB1 signalosome
0.0 0.0 REACTOME_DESTABILIZATION_OF_MRNA_BY_TRISTETRAPROLIN_TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0 0.2 REACTOME_HORMONE_LIGAND_BINDING_RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 0.2 REACTOME_SIGNALING_BY_ACTIVATED_POINT_MUTANTS_OF_FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.0 0.6 REACTOME_G_ALPHA_Z_SIGNALLING_EVENTS Genes involved in G alpha (z) signalling events
0.0 0.1 REACTOME_INFLUENZA_VIRAL_RNA_TRANSCRIPTION_AND_REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
0.0 0.2 REACTOME_SYNTHESIS_SECRETION_AND_DEACYLATION_OF_GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.3 REACTOME_PEROXISOMAL_LIPID_METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.4 REACTOME_ACTIVATED_NOTCH1_TRANSMITS_SIGNAL_TO_THE_NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.2 REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.0 0.2 REACTOME_CS_DS_DEGRADATION Genes involved in CS/DS degradation
0.0 0.2 REACTOME_AMINE_DERIVED_HORMONES Genes involved in Amine-derived hormones