Motif ID: HINFP

Z-value: 0.921


Transcription factors associated with HINFP:

Gene SymbolEntrez IDGene Name
HINFP ENSG00000172273.8 HINFP

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
HINFPhg19_v2_chr11_+_118992269_118992334-0.359.1e-02Click!


Activity profile for motif HINFP.

activity profile for motif HINFP


Sorted Z-values histogram for motif HINFP

Sorted Z-values for motif HINFP



Network of associatons between targets according to the STRING database.



First level regulatory network of HINFP

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr4_-_149363662 3.959 ENST00000355292.3
ENST00000358102.3
NR3C2

nuclear receptor subfamily 3, group C, member 2

chr1_-_36916066 3.453 ENST00000315643.9
OSCP1
organic solute carrier partner 1
chr17_+_11501748 3.141 ENST00000262442.4
ENST00000579828.1
DNAH9

dynein, axonemal, heavy chain 9

chr9_+_34458771 2.712 ENST00000437363.1
ENST00000242317.4
DNAI1

dynein, axonemal, intermediate chain 1

chr1_-_36915880 2.622 ENST00000445843.3
OSCP1
organic solute carrier partner 1
chr1_-_36916011 2.311 ENST00000356637.5
ENST00000354267.3
ENST00000235532.5
OSCP1


organic solute carrier partner 1


chr11_+_62104897 2.221 ENST00000415229.2
ENST00000535727.1
ENST00000301776.5
ASRGL1


asparaginase like 1


chr22_+_23487513 1.939 ENST00000263116.2
ENST00000341989.4
RAB36

RAB36, member RAS oncogene family

chrX_-_38186811 1.931 ENST00000318842.7
RPGR
retinitis pigmentosa GTPase regulator
chrX_-_38186775 1.901 ENST00000339363.3
ENST00000309513.3
ENST00000338898.3
ENST00000342811.3
ENST00000378505.2
RPGR




retinitis pigmentosa GTPase regulator




chr3_+_49449636 1.791 ENST00000273590.3
TCTA
T-cell leukemia translocation altered
chr2_+_120301997 1.749 ENST00000602047.1
PCDP1
Primary ciliary dyskinesia protein 1
chr2_+_120302041 1.734 ENST00000442513.3
ENST00000413369.3
PCDP1

Primary ciliary dyskinesia protein 1

chr16_-_54963026 1.611 ENST00000560208.1
ENST00000557792.1
CRNDE

colorectal neoplasia differentially expressed (non-protein coding)

chr1_-_217262969 1.607 ENST00000361525.3
ESRRG
estrogen-related receptor gamma
chr1_+_61547405 1.563 ENST00000371189.4
NFIA
nuclear factor I/A
chr1_-_217262933 1.426 ENST00000359162.2
ESRRG
estrogen-related receptor gamma
chr16_-_54962625 1.365 ENST00000559432.1
CRNDE
colorectal neoplasia differentially expressed (non-protein coding)
chr17_-_4545170 1.355 ENST00000576394.1
ENST00000574640.1
ALOX15

arachidonate 15-lipoxygenase

chr22_+_29168652 1.344 ENST00000249064.4
ENST00000444523.1
ENST00000448492.2
ENST00000421503.2
CCDC117



coiled-coil domain containing 117




Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 93 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 5.8 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.1 4.1 GO:0042073 intraciliary transport(GO:0042073)
0.1 3.8 GO:0003341 cilium movement(GO:0003341)
0.0 3.0 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.1 2.7 GO:0036158 outer dynein arm assembly(GO:0036158)
0.1 2.7 GO:0072189 ureter development(GO:0072189)
0.8 2.5 GO:0050760 negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
0.8 2.4 GO:2001301 lipoxin biosynthetic process(GO:2001301) lipoxin A4 metabolic process(GO:2001302) lipoxin A4 biosynthetic process(GO:2001303)
0.2 2.2 GO:0006528 asparagine metabolic process(GO:0006528)
0.1 1.9 GO:0016578 histone deubiquitination(GO:0016578)
0.3 1.8 GO:0072675 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.1 1.7 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.3 1.6 GO:0032380 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.2 1.5 GO:0009450 acetate metabolic process(GO:0006083) glutamate decarboxylation to succinate(GO:0006540) gamma-aminobutyric acid catabolic process(GO:0009450)
0.1 1.4 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
0.1 1.4 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.4 1.3 GO:0015882 L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904)
0.0 1.2 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.4 1.1 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.1 1.1 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 38 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 9.7 GO:0009925 basal plasma membrane(GO:0009925)
0.1 3.8 GO:0030286 dynein complex(GO:0030286)
0.0 3.8 GO:0001750 photoreceptor outer segment(GO:0001750)
0.2 2.7 GO:0036157 outer dynein arm(GO:0036157)
0.3 2.5 GO:1990761 growth cone lamellipodium(GO:1990761) growth cone filopodium(GO:1990812)
0.0 2.2 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.1 1.7 GO:0000124 SAGA complex(GO:0000124)
0.1 1.6 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 1.6 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.3 1.1 GO:0016939 kinesin II complex(GO:0016939)
0.1 1.1 GO:0061574 ASAP complex(GO:0061574)
0.0 1.1 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.2 0.8 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.1 0.8 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.8 GO:0032591 dendritic spine membrane(GO:0032591)
0.1 0.7 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.1 0.5 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.1 0.5 GO:0044294 dendritic growth cone(GO:0044294)
0.0 0.5 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.5 GO:0034366 spherical high-density lipoprotein particle(GO:0034366) chromaffin granule(GO:0042583)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 54 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 6.5 GO:0045503 dynein light chain binding(GO:0045503)
0.0 3.9 GO:0005496 steroid binding(GO:0005496)
0.4 3.0 GO:0050682 AF-2 domain binding(GO:0050682)
0.1 2.5 GO:0048156 tau protein binding(GO:0048156)
0.8 2.4 GO:0047977 hepoxilin-epoxide hydrolase activity(GO:0047977)
0.7 2.2 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.0 1.8 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 1.6 GO:0042626 ATPase activity, coupled to transmembrane movement of substances(GO:0042626)
0.0 1.5 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor(GO:0016620)
0.5 1.4 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
0.4 1.3 GO:0070890 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.0 1.1 GO:0030507 spectrin binding(GO:0030507)
0.0 1.1 GO:0004407 histone deacetylase activity(GO:0004407)
0.2 0.9 GO:0031685 adenosine receptor binding(GO:0031685)
0.0 0.9 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 0.8 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.0 0.8 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.7 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.7 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.1 0.6 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241)

Gene overrepresentation in C2:CP category:

Showing 1 to 10 of 10 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.9 PID_HEDGEHOG_GLI_PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 2.6 PID_ERA_GENOMIC_PATHWAY Validated nuclear estrogen receptor alpha network
0.0 2.4 PID_ARF6_PATHWAY Arf6 signaling events
0.0 2.4 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.0 1.8 PID_IL4_2PATHWAY IL4-mediated signaling events
0.0 0.9 PID_EPHRINB_REV_PATHWAY Ephrin B reverse signaling
0.0 0.6 PID_INSULIN_PATHWAY Insulin Pathway
0.0 0.5 ST_WNT_BETA_CATENIN_PATHWAY Wnt/beta-catenin Pathway
0.0 0.4 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.4 PID_HDAC_CLASSIII_PATHWAY Signaling events mediated by HDAC Class III

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 16 of 16 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 4.8 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 1.6 REACTOME_ABCA_TRANSPORTERS_IN_LIPID_HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 1.5 REACTOME_GABA_SYNTHESIS_RELEASE_REUPTAKE_AND_DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 1.4 REACTOME_LYSOSOME_VESICLE_BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.7 REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.7 REACTOME_MRNA_SPLICING_MINOR_PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 0.6 REACTOME_CTNNB1_PHOSPHORYLATION_CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.6 REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.5 REACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.5 REACTOME_SIGNAL_ATTENUATION Genes involved in Signal attenuation
0.0 0.4 REACTOME_GAP_JUNCTION_DEGRADATION Genes involved in Gap junction degradation
0.0 0.4 REACTOME_ACTIVATION_OF_RAC Genes involved in Activation of Rac
0.0 0.4 REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.4 REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.2 REACTOME_INHIBITION_OF_INSULIN_SECRETION_BY_ADRENALINE_NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 0.2 REACTOME_METABOLISM_OF_RNA Genes involved in Metabolism of RNA