Motif ID: HIVEP1
Z-value: 0.877
Transcription factors associated with HIVEP1:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| HIVEP1 | ENSG00000095951.12 | HIVEP1 |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| HIVEP1 | hg19_v2_chr6_+_12012536_12012571 | -0.44 | 3.2e-02 | Click! |
Top targets:
Showing 1 to 20 of 200 entries
Gene overrepresentation in biological_process category:
Showing 1 to 20 of 126 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 3.0 | GO:0031295 | T cell costimulation(GO:0031295) |
| 0.6 | 2.2 | GO:0034343 | type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344) |
| 0.5 | 2.1 | GO:0002503 | peptide antigen assembly with MHC class II protein complex(GO:0002503) |
| 0.2 | 2.1 | GO:0045329 | carnitine biosynthetic process(GO:0045329) |
| 0.1 | 1.6 | GO:0072540 | T-helper 17 cell lineage commitment(GO:0072540) |
| 0.2 | 1.5 | GO:0002480 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480) |
| 0.5 | 1.4 | GO:0052047 | interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047) |
| 0.1 | 1.3 | GO:0032688 | negative regulation of interferon-beta production(GO:0032688) |
| 0.1 | 1.1 | GO:0032097 | positive regulation of response to food(GO:0032097) positive regulation of appetite(GO:0032100) |
| 0.2 | 0.8 | GO:0002901 | mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906) |
| 0.1 | 0.8 | GO:0038161 | prolactin signaling pathway(GO:0038161) |
| 0.1 | 0.8 | GO:0010819 | regulation of T cell chemotaxis(GO:0010819) |
| 0.0 | 0.8 | GO:1904659 | hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659) |
| 0.0 | 0.8 | GO:0048247 | lymphocyte chemotaxis(GO:0048247) |
| 0.0 | 0.8 | GO:0045776 | negative regulation of blood pressure(GO:0045776) |
| 0.1 | 0.7 | GO:0001920 | negative regulation of receptor recycling(GO:0001920) |
| 0.1 | 0.7 | GO:0006030 | chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032) |
| 0.0 | 0.6 | GO:0051601 | exocyst localization(GO:0051601) |
| 0.0 | 0.6 | GO:0046710 | GDP metabolic process(GO:0046710) |
| 0.0 | 0.6 | GO:0001525 | angiogenesis(GO:0001525) |
Gene overrepresentation in cellular_component category:
Showing 1 to 20 of 48 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 5.7 | GO:0042613 | MHC class II protein complex(GO:0042613) |
| 0.1 | 1.6 | GO:0033256 | I-kappaB/NF-kappaB complex(GO:0033256) |
| 0.1 | 1.5 | GO:0042611 | MHC protein complex(GO:0042611) |
| 0.1 | 1.4 | GO:0005577 | fibrinogen complex(GO:0005577) |
| 0.1 | 0.9 | GO:0071953 | elastic fiber(GO:0071953) |
| 0.0 | 0.8 | GO:0032591 | dendritic spine membrane(GO:0032591) |
| 0.0 | 0.8 | GO:0031904 | endosome lumen(GO:0031904) |
| 0.0 | 0.6 | GO:0000145 | exocyst(GO:0000145) |
| 0.2 | 0.5 | GO:1990923 | PET complex(GO:1990923) |
| 0.0 | 0.5 | GO:1902711 | GABA-A receptor complex(GO:1902711) |
| 0.0 | 0.5 | GO:0042101 | T cell receptor complex(GO:0042101) |
| 0.0 | 0.5 | GO:0042571 | immunoglobulin complex, circulating(GO:0042571) |
| 0.1 | 0.4 | GO:0070288 | intracellular ferritin complex(GO:0008043) ferritin complex(GO:0070288) |
| 0.1 | 0.4 | GO:0030061 | mitochondrial crista(GO:0030061) |
| 0.0 | 0.4 | GO:0002116 | semaphorin receptor complex(GO:0002116) |
| 0.0 | 0.4 | GO:0031233 | intrinsic component of external side of plasma membrane(GO:0031233) |
| 0.1 | 0.3 | GO:0005889 | hydrogen:potassium-exchanging ATPase complex(GO:0005889) |
| 0.1 | 0.3 | GO:0008282 | ATP-sensitive potassium channel complex(GO:0008282) |
| 0.0 | 0.3 | GO:0008537 | proteasome activator complex(GO:0008537) |
| 0.0 | 0.3 | GO:0042406 | extrinsic component of endoplasmic reticulum membrane(GO:0042406) |
Gene overrepresentation in molecular_function category:
Showing 1 to 20 of 83 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 4.1 | GO:0032395 | MHC class II receptor activity(GO:0032395) |
| 0.5 | 2.1 | GO:0008336 | gamma-butyrobetaine dioxygenase activity(GO:0008336) |
| 0.0 | 2.1 | GO:0003727 | single-stranded RNA binding(GO:0003727) |
| 0.0 | 1.4 | GO:0004722 | protein serine/threonine phosphatase activity(GO:0004722) |
| 0.0 | 1.1 | GO:0005184 | neuropeptide hormone activity(GO:0005184) |
| 0.0 | 1.0 | GO:0042605 | peptide antigen binding(GO:0042605) |
| 0.0 | 1.0 | GO:0016504 | peptidase activator activity(GO:0016504) |
| 0.0 | 0.9 | GO:0016641 | oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641) |
| 0.0 | 0.9 | GO:0048020 | CCR chemokine receptor binding(GO:0048020) |
| 0.2 | 0.8 | GO:0042289 | MHC class II protein binding(GO:0042289) |
| 0.2 | 0.8 | GO:0004925 | prolactin receptor activity(GO:0004925) |
| 0.0 | 0.8 | GO:0023026 | MHC class II protein complex binding(GO:0023026) |
| 0.1 | 0.7 | GO:0005166 | neurotrophin p75 receptor binding(GO:0005166) |
| 0.1 | 0.7 | GO:0004568 | chitinase activity(GO:0004568) |
| 0.0 | 0.7 | GO:0031624 | ubiquitin conjugating enzyme binding(GO:0031624) |
| 0.0 | 0.7 | GO:0001205 | transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205) |
| 0.0 | 0.7 | GO:0005227 | calcium activated cation channel activity(GO:0005227) |
| 0.1 | 0.6 | GO:0048248 | CXCR3 chemokine receptor binding(GO:0048248) |
| 0.0 | 0.6 | GO:0061578 | Lys63-specific deubiquitinase activity(GO:0061578) |
| 0.0 | 0.6 | GO:0004385 | guanylate kinase activity(GO:0004385) |
Gene overrepresentation in C2:CP category:
Showing 1 to 12 of 12 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.4 | PID_INTEGRIN5_PATHWAY | Beta5 beta6 beta7 and beta8 integrin cell surface interactions |
| 0.0 | 1.4 | PID_IL12_STAT4_PATHWAY | IL12 signaling mediated by STAT4 |
| 0.0 | 1.4 | ST_TUMOR_NECROSIS_FACTOR_PATHWAY | Tumor Necrosis Factor Pathway. |
| 0.0 | 1.3 | PID_IL12_2PATHWAY | IL12-mediated signaling events |
| 0.0 | 1.0 | PID_CXCR3_PATHWAY | CXCR3-mediated signaling events |
| 0.0 | 0.9 | PID_ERBB4_PATHWAY | ErbB4 signaling events |
| 0.0 | 0.5 | PID_NFKAPPAB_ATYPICAL_PATHWAY | Atypical NF-kappaB pathway |
| 0.0 | 0.5 | SA_TRKA_RECEPTOR | The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth. |
| 0.0 | 0.4 | PID_WNT_CANONICAL_PATHWAY | Canonical Wnt signaling pathway |
| 0.0 | 0.4 | PID_HDAC_CLASSIII_PATHWAY | Signaling events mediated by HDAC Class III |
| 0.0 | 0.3 | SA_CASPASE_CASCADE | Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade. |
| 0.0 | 0.2 | ST_IL_13_PATHWAY | Interleukin 13 (IL-13) Pathway |
Gene overrepresentation in C2:CP:REACTOME category:
Showing 1 to 20 of 22 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 2.8 | REACTOME_TRANSLOCATION_OF_ZAP_70_TO_IMMUNOLOGICAL_SYNAPSE | Genes involved in Translocation of ZAP-70 to Immunological synapse |
| 0.1 | 2.4 | REACTOME_TRAF3_DEPENDENT_IRF_ACTIVATION_PATHWAY | Genes involved in TRAF3-dependent IRF activation pathway |
| 0.0 | 2.1 | REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES | Genes involved in Chemokine receptors bind chemokines |
| 0.2 | 1.5 | REACTOME_ENDOSOMAL_VACUOLAR_PATHWAY | Genes involved in Endosomal/Vacuolar pathway |
| 0.0 | 1.4 | REACTOME_GRB2_SOS_PROVIDES_LINKAGE_TO_MAPK_SIGNALING_FOR_INTERGRINS_ | Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins |
| 0.0 | 1.0 | REACTOME_TRAF6_MEDIATED_NFKB_ACTIVATION | Genes involved in TRAF6 mediated NF-kB activation |
| 0.0 | 0.8 | REACTOME_PROLACTIN_RECEPTOR_SIGNALING | Genes involved in Prolactin receptor signaling |
| 0.0 | 0.6 | REACTOME_NEGATIVE_REGULATORS_OF_RIG_I_MDA5_SIGNALING | Genes involved in Negative regulators of RIG-I/MDA5 signaling |
| 0.0 | 0.5 | REACTOME_SIGNALLING_TO_P38_VIA_RIT_AND_RIN | Genes involved in Signalling to p38 via RIT and RIN |
| 0.0 | 0.5 | REACTOME_GABA_A_RECEPTOR_ACTIVATION | Genes involved in GABA A receptor activation |
| 0.0 | 0.4 | REACTOME_CS_DS_DEGRADATION | Genes involved in CS/DS degradation |
| 0.0 | 0.4 | REACTOME_OTHER_SEMAPHORIN_INTERACTIONS | Genes involved in Other semaphorin interactions |
| 0.0 | 0.4 | REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS | Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis |
| 0.0 | 0.4 | REACTOME_RAP1_SIGNALLING | Genes involved in Rap1 signalling |
| 0.0 | 0.3 | REACTOME_PECAM1_INTERACTIONS | Genes involved in PECAM1 interactions |
| 0.0 | 0.3 | REACTOME_FACILITATIVE_NA_INDEPENDENT_GLUCOSE_TRANSPORTERS | Genes involved in Facilitative Na+-independent glucose transporters |
| 0.0 | 0.3 | REACTOME_RNA_POL_III_CHAIN_ELONGATION | Genes involved in RNA Polymerase III Chain Elongation |
| 0.0 | 0.3 | REACTOME_SYNTHESIS_OF_PIPS_AT_THE_GOLGI_MEMBRANE | Genes involved in Synthesis of PIPs at the Golgi membrane |
| 0.0 | 0.2 | REACTOME_GAMMA_CARBOXYLATION_TRANSPORT_AND_AMINO_TERMINAL_CLEAVAGE_OF_PROTEINS | Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins |
| 0.0 | 0.2 | REACTOME_ACTIVATION_OF_THE_AP1_FAMILY_OF_TRANSCRIPTION_FACTORS | Genes involved in Activation of the AP-1 family of transcription factors |
