Motif ID: HNF4G
Z-value: 1.216
Transcription factors associated with HNF4G:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| HNF4G | ENSG00000164749.7 | HNF4G |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| HNF4G | hg19_v2_chr8_+_76452097_76452126 | 0.73 | 4.7e-05 | Click! |
Top targets:
Showing 1 to 20 of 200 entries
Gene overrepresentation in biological_process category:
Showing 1 to 20 of 204 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 3.7 | 14.8 | GO:0046271 | phenylpropanoid catabolic process(GO:0046271) |
| 0.4 | 9.2 | GO:0019373 | epoxygenase P450 pathway(GO:0019373) |
| 1.5 | 7.5 | GO:0002415 | immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415) |
| 1.4 | 7.0 | GO:1904977 | lymphatic endothelial cell migration(GO:1904977) |
| 0.1 | 5.1 | GO:0048791 | calcium ion-regulated exocytosis of neurotransmitter(GO:0048791) |
| 1.2 | 4.6 | GO:2000768 | glomerular parietal epithelial cell differentiation(GO:0072139) positive regulation of nephron tubule epithelial cell differentiation(GO:2000768) |
| 0.8 | 3.9 | GO:0009804 | coumarin metabolic process(GO:0009804) |
| 0.8 | 3.8 | GO:0060741 | prostate gland stromal morphogenesis(GO:0060741) |
| 1.2 | 3.7 | GO:0033214 | iron assimilation(GO:0033212) iron assimilation by chelation and transport(GO:0033214) positive regulation of bone mineralization involved in bone maturation(GO:1900159) negative regulation of tumor necrosis factor (ligand) superfamily member 11 production(GO:2000308) |
| 0.6 | 3.7 | GO:0035469 | determination of pancreatic left/right asymmetry(GO:0035469) |
| 0.5 | 3.5 | GO:0098535 | de novo centriole assembly(GO:0098535) |
| 0.0 | 3.4 | GO:0001895 | retina homeostasis(GO:0001895) |
| 0.9 | 2.8 | GO:0090076 | relaxation of skeletal muscle(GO:0090076) |
| 0.1 | 2.7 | GO:0071801 | regulation of podosome assembly(GO:0071801) |
| 0.0 | 2.7 | GO:0006910 | phagocytosis, recognition(GO:0006910) |
| 0.2 | 2.5 | GO:0070070 | proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072) |
| 0.8 | 2.4 | GO:0050902 | leukocyte adhesive activation(GO:0050902) |
| 0.8 | 2.3 | GO:0001798 | positive regulation of type IIa hypersensitivity(GO:0001798) positive regulation of type II hypersensitivity(GO:0002894) |
| 0.6 | 2.3 | GO:0032972 | diaphragm contraction(GO:0002086) regulation of muscle filament sliding speed(GO:0032972) |
| 0.4 | 2.1 | GO:1902998 | macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998) |
Gene overrepresentation in cellular_component category:
Showing 1 to 20 of 90 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 10.7 | GO:0005881 | cytoplasmic microtubule(GO:0005881) |
| 0.1 | 6.4 | GO:0055038 | recycling endosome membrane(GO:0055038) |
| 0.1 | 4.7 | GO:0030315 | T-tubule(GO:0030315) |
| 0.3 | 4.6 | GO:0042622 | photoreceptor outer segment membrane(GO:0042622) |
| 0.0 | 4.1 | GO:0016323 | basolateral plasma membrane(GO:0016323) |
| 0.5 | 3.7 | GO:0097013 | phagocytic vesicle lumen(GO:0097013) |
| 0.7 | 3.5 | GO:0098536 | deuterosome(GO:0098536) |
| 0.1 | 2.9 | GO:0042571 | immunoglobulin complex, circulating(GO:0042571) |
| 0.0 | 2.7 | GO:0032993 | protein-DNA complex(GO:0032993) |
| 0.0 | 2.6 | GO:0001772 | immunological synapse(GO:0001772) |
| 0.3 | 2.5 | GO:0000220 | vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220) |
| 0.1 | 2.5 | GO:0042579 | peroxisome(GO:0005777) microbody(GO:0042579) |
| 0.0 | 2.4 | GO:0005782 | peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907) |
| 0.4 | 2.3 | GO:1990584 | cardiac Troponin complex(GO:1990584) |
| 0.0 | 2.3 | GO:0030672 | synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501) |
| 0.0 | 2.2 | GO:0097014 | axoneme(GO:0005930) ciliary plasm(GO:0097014) |
| 0.1 | 2.1 | GO:0097418 | neurofibrillary tangle(GO:0097418) |
| 0.0 | 2.1 | GO:0031514 | motile cilium(GO:0031514) |
| 0.1 | 1.9 | GO:0001518 | voltage-gated sodium channel complex(GO:0001518) |
| 0.0 | 1.9 | GO:0035578 | azurophil granule lumen(GO:0035578) |
Gene overrepresentation in molecular_function category:
Showing 1 to 20 of 150 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.2 | 24.2 | GO:0008392 | arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392) |
| 0.1 | 5.7 | GO:0005544 | calcium-dependent phospholipid binding(GO:0005544) |
| 0.1 | 5.3 | GO:0019003 | GDP binding(GO:0019003) |
| 0.5 | 4.6 | GO:0004565 | beta-galactosidase activity(GO:0004565) |
| 0.1 | 4.6 | GO:0042805 | actinin binding(GO:0042805) |
| 0.7 | 4.0 | GO:0042577 | lipid phosphatase activity(GO:0042577) |
| 0.2 | 3.8 | GO:0003680 | AT DNA binding(GO:0003680) |
| 0.1 | 3.7 | GO:0070840 | dynein complex binding(GO:0070840) |
| 0.1 | 3.7 | GO:0001530 | lipopolysaccharide binding(GO:0001530) |
| 0.0 | 3.6 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
| 0.2 | 2.9 | GO:0001011 | transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087) |
| 0.2 | 2.8 | GO:0015467 | G-protein activated inward rectifier potassium channel activity(GO:0015467) |
| 0.1 | 2.5 | GO:0046961 | proton-transporting ATPase activity, rotational mechanism(GO:0046961) |
| 0.0 | 2.5 | GO:0005178 | integrin binding(GO:0005178) |
| 0.1 | 2.4 | GO:0048020 | CCR chemokine receptor binding(GO:0048020) |
| 0.2 | 2.3 | GO:0031013 | troponin I binding(GO:0031013) |
| 0.1 | 2.2 | GO:0102391 | decanoate--CoA ligase activity(GO:0102391) |
| 0.0 | 2.2 | GO:0001664 | G-protein coupled receptor binding(GO:0001664) |
| 0.2 | 2.1 | GO:0005005 | transmembrane-ephrin receptor activity(GO:0005005) |
| 0.1 | 2.1 | GO:0051787 | misfolded protein binding(GO:0051787) |
Gene overrepresentation in C2:CP category:
Showing 1 to 20 of 21 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 6.7 | NABA_ECM_AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
| 0.1 | 6.3 | PID_HNF3A_PATHWAY | FOXA1 transcription factor network |
| 0.0 | 4.1 | PID_AR_PATHWAY | Coregulation of Androgen receptor activity |
| 0.0 | 3.3 | PID_CMYB_PATHWAY | C-MYB transcription factor network |
| 0.0 | 1.7 | PID_ALK1_PATHWAY | ALK1 signaling events |
| 0.1 | 1.2 | PID_ERB_GENOMIC_PATHWAY | Validated nuclear estrogen receptor beta network |
| 0.0 | 1.2 | PID_BETA_CATENIN_DEG_PATHWAY | Degradation of beta catenin |
| 0.0 | 1.2 | PID_CD40_PATHWAY | CD40/CD40L signaling |
| 0.0 | 1.2 | PID_CD8_TCR_PATHWAY | TCR signaling in naïve CD8+ T cells |
| 0.0 | 1.2 | PID_MYC_REPRESS_PATHWAY | Validated targets of C-MYC transcriptional repression |
| 0.0 | 1.0 | PID_EPHB_FWD_PATHWAY | EPHB forward signaling |
| 0.0 | 1.0 | PID_EPHA_FWDPATHWAY | EPHA forward signaling |
| 0.0 | 1.0 | PID_REG_GR_PATHWAY | Glucocorticoid receptor regulatory network |
| 0.0 | 0.8 | PID_IL12_STAT4_PATHWAY | IL12 signaling mediated by STAT4 |
| 0.0 | 0.7 | PID_SYNDECAN_1_PATHWAY | Syndecan-1-mediated signaling events |
| 0.0 | 0.6 | PID_HEDGEHOG_2PATHWAY | Signaling events mediated by the Hedgehog family |
| 0.0 | 0.5 | PID_IL2_PI3K_PATHWAY | IL2 signaling events mediated by PI3K |
| 0.0 | 0.3 | ST_PAC1_RECEPTOR_PATHWAY | PAC1 Receptor Pathway |
| 0.0 | 0.2 | ST_INTERFERON_GAMMA_PATHWAY | Interferon gamma pathway. |
| 0.0 | 0.2 | PID_LPA4_PATHWAY | LPA4-mediated signaling events |
Gene overrepresentation in C2:CP:REACTOME category:
Showing 1 to 20 of 40 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.0 | 18.9 | REACTOME_XENOBIOTICS | Genes involved in Xenobiotics |
| 0.1 | 6.3 | REACTOME_LATENT_INFECTION_OF_HOMO_SAPIENS_WITH_MYCOBACTERIUM_TUBERCULOSIS | Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis |
| 0.0 | 4.8 | REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2_ | Genes involved in Response to elevated platelet cytosolic Ca2+ |
| 0.1 | 2.9 | REACTOME_MYOGENESIS | Genes involved in Myogenesis |
| 0.2 | 2.6 | REACTOME_RECYCLING_OF_BILE_ACIDS_AND_SALTS | Genes involved in Recycling of bile acids and salts |
| 0.0 | 2.5 | REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES | Genes involved in Chemokine receptors bind chemokines |
| 0.1 | 2.4 | REACTOME_INHIBITION_OF_VOLTAGE_GATED_CA2_CHANNELS_VIA_GBETA_GAMMA_SUBUNITS | Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits |
| 0.1 | 2.2 | REACTOME_INITIAL_TRIGGERING_OF_COMPLEMENT | Genes involved in Initial triggering of complement |
| 0.1 | 2.2 | REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS | Genes involved in Termination of O-glycan biosynthesis |
| 0.2 | 1.7 | REACTOME_PROSTANOID_LIGAND_RECEPTORS | Genes involved in Prostanoid ligand receptors |
| 0.0 | 1.6 | REACTOME_RECRUITMENT_OF_MITOTIC_CENTROSOME_PROTEINS_AND_COMPLEXES | Genes involved in Recruitment of mitotic centrosome proteins and complexes |
| 0.1 | 1.5 | REACTOME_TRANSLOCATION_OF_ZAP_70_TO_IMMUNOLOGICAL_SYNAPSE | Genes involved in Translocation of ZAP-70 to Immunological synapse |
| 0.1 | 1.5 | REACTOME_ABCA_TRANSPORTERS_IN_LIPID_HOMEOSTASIS | Genes involved in ABCA transporters in lipid homeostasis |
| 0.0 | 1.4 | REACTOME_GLYCOSPHINGOLIPID_METABOLISM | Genes involved in Glycosphingolipid metabolism |
| 0.1 | 1.3 | REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS | Genes involved in Passive Transport by Aquaporins |
| 0.1 | 1.3 | REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION | Genes involved in Mitochondrial Fatty Acid Beta-Oxidation |
| 0.0 | 1.3 | REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES | Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates |
| 0.0 | 1.3 | REACTOME_REGULATION_OF_INSULIN_SECRETION | Genes involved in Regulation of Insulin Secretion |
| 0.0 | 1.1 | REACTOME_ADVANCED_GLYCOSYLATION_ENDPRODUCT_RECEPTOR_SIGNALING | Genes involved in Advanced glycosylation endproduct receptor signaling |
| 0.0 | 1.0 | REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT | Genes involved in Mitochondrial Protein Import |
