Motif ID: HOMEZ

Z-value: 0.867


Transcription factors associated with HOMEZ:

Gene SymbolEntrez IDGene Name
HOMEZ ENSG00000215271.6 HOMEZ

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
HOMEZhg19_v2_chr14_-_23755297_237553500.555.4e-03Click!


Activity profile for motif HOMEZ.

activity profile for motif HOMEZ


Sorted Z-values histogram for motif HOMEZ

Sorted Z-values for motif HOMEZ



Network of associatons between targets according to the STRING database.



First level regulatory network of HOMEZ

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr4_+_70861647 4.517 ENST00000246895.4
ENST00000381060.2
 STATH

statherin

chr11_+_62104897 4.120 ENST00000415229.2
ENST00000535727.1
ENST00000301776.5
 ASRGL1


asparaginase like 1


chr19_-_55677920 3.418 ENST00000524407.2
ENST00000526003.1
ENST00000534170.1
 DNAAF3


dynein, axonemal, assembly factor 3


chr19_-_55677999 3.104 ENST00000532817.1
ENST00000527223.2
ENST00000391720.4
 DNAAF3


dynein, axonemal, assembly factor 3


chr9_-_138391692 3.053 ENST00000429260.2
 C9orf116
chromosome 9 open reading frame 116
chr7_+_48075108 3.044 ENST00000420324.1
ENST00000435376.1
ENST00000430738.1
ENST00000348904.3
ENST00000539619.1
 C7orf57




chromosome 7 open reading frame 57




chr9_+_124926856 2.965 ENST00000418632.1
 MORN5
MORN repeat containing 5
chr6_-_33041378 2.883 ENST00000428995.1
 HLA-DPA1
major histocompatibility complex, class II, DP alpha 1
chr19_-_6433765 2.570 ENST00000321510.6
 SLC25A41
solute carrier family 25, member 41
chr12_-_71551652 2.545 ENST00000546561.1
 TSPAN8
tetraspanin 8
chr12_-_112450915 2.535 ENST00000437003.2
ENST00000552374.2
ENST00000550831.3
ENST00000354825.3
ENST00000549537.2
ENST00000355445.3
 TMEM116





transmembrane protein 116





chr4_-_70518941 2.376 ENST00000286604.4
ENST00000505512.1
ENST00000514019.1
 UGT2A1

UGT2A1
UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus

UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus
chr12_-_71551868 2.372 ENST00000247829.3
 TSPAN8
tetraspanin 8
chr22_-_50970919 2.298 ENST00000329363.4
ENST00000437588.1
 ODF3B

outer dense fiber of sperm tails 3B

chr5_-_110062384 2.150 ENST00000429839.2
 TMEM232
transmembrane protein 232
chr1_-_104239076 2.144 ENST00000370080.3
 AMY1B
amylase, alpha 1B (salivary)
chr3_-_107941209 1.987 ENST00000492106.1
 IFT57
intraflagellar transport 57 homolog (Chlamydomonas)
chr16_+_58283814 1.866 ENST00000443128.2
ENST00000219299.4
 CCDC113

coiled-coil domain containing 113

chr6_+_33048222 1.595 ENST00000428835.1
 HLA-DPB1
major histocompatibility complex, class II, DP beta 1
chr11_+_86106208 1.580 ENST00000528728.1
 CCDC81
coiled-coil domain containing 81

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 133 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 9.8 GO:0044458 motile cilium assembly(GO:0044458)
0.1 4.6 GO:1900047 negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.3 4.5 GO:0046541 saliva secretion(GO:0046541)
0.5 4.1 GO:0006528 asparagine metabolic process(GO:0006528)
0.0 3.8 GO:0032729 positive regulation of interferon-gamma production(GO:0032729)
0.0 2.9 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.1 2.8 GO:0052695 cellular glucuronidation(GO:0052695)
0.2 2.6 GO:0015866 ADP transport(GO:0015866)
0.0 2.4 GO:0009988 cell-cell recognition(GO:0009988)
0.2 1.7 GO:0033088 negative regulation of immature T cell proliferation in thymus(GO:0033088)
0.0 1.5 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.3 1.4 GO:0001970 positive regulation of activation of membrane attack complex(GO:0001970)
0.0 1.3 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0 1.3 GO:0043171 peptide catabolic process(GO:0043171)
0.3 1.0 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.2 1.0 GO:0048496 maintenance of organ identity(GO:0048496)
0.1 1.0 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 1.0 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 1.0 GO:0007099 centriole replication(GO:0007099)
0.3 0.9 GO:1902161 transepithelial water transport(GO:0035377) positive regulation of cyclic nucleotide-gated ion channel activity(GO:1902161)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 53 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 4.1 GO:0042613 MHC class II protein complex(GO:0042613)
0.3 3.6 GO:0044292 dendrite terminus(GO:0044292)
0.0 2.1 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.2 1.5 GO:0000836 Hrd1p ubiquitin ligase complex(GO:0000836)
0.1 1.5 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.0 1.5 GO:0034451 centriolar satellite(GO:0034451)
0.2 1.4 GO:0005579 membrane attack complex(GO:0005579)
0.0 1.4 GO:0035580 specific granule lumen(GO:0035580)
0.1 1.2 GO:0043220 Schmidt-Lanterman incisure(GO:0043220)
0.1 1.0 GO:0000109 nucleotide-excision repair complex(GO:0000109)
0.2 0.9 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.0 0.9 GO:0030992 intraciliary transport particle B(GO:0030992)
0.1 0.8 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.1 0.8 GO:0036128 CatSper complex(GO:0036128)
0.0 0.7 GO:0097542 ciliary tip(GO:0097542)
0.0 0.6 GO:0005833 hemoglobin complex(GO:0005833)
0.0 0.6 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.2 0.5 GO:0018444 translation release factor complex(GO:0018444)
0.1 0.5 GO:0042825 TAP complex(GO:0042825)
0.1 0.5 GO:1990130 Iml1 complex(GO:1990130)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 92 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 4.9 GO:0005178 integrin binding(GO:0005178)
1.5 4.5 GO:0046848 hydroxyapatite binding(GO:0046848)
1.4 4.1 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.0 3.2 GO:0017137 Rab GTPase binding(GO:0017137)
0.1 2.8 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.2 2.6 GO:0015217 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.2 2.5 GO:0032395 MHC class II receptor activity(GO:0032395)
0.2 1.7 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.1 1.7 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.1 1.6 GO:0070330 aromatase activity(GO:0070330)
0.1 1.6 GO:0042605 peptide antigen binding(GO:0042605)
0.2 1.4 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.1 1.3 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.1 1.3 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 1.2 GO:0016279 protein-lysine N-methyltransferase activity(GO:0016279)
0.2 1.0 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
0.2 1.0 GO:0035276 ethanol binding(GO:0035276)
0.3 0.9 GO:0005260 channel-conductance-controlling ATPase activity(GO:0005260)
0.1 0.9 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.0 0.8 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)

Gene overrepresentation in C2:CP category:

Showing 1 to 2 of 2 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.7 PID_ERBB_NETWORK_PATHWAY ErbB receptor signaling network
0.0 0.7 ST_INTERFERON_GAMMA_PATHWAY Interferon gamma pathway.

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 20 of 26 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 4.5 REACTOME_TRANSLOCATION_OF_ZAP_70_TO_IMMUNOLOGICAL_SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.1 2.4 REACTOME_GLUCURONIDATION Genes involved in Glucuronidation
0.2 2.1 REACTOME_DIGESTION_OF_DIETARY_CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.1 1.7 REACTOME_DOWNREGULATION_OF_ERBB2_ERBB3_SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 1.7 REACTOME_COMPLEMENT_CASCADE Genes involved in Complement cascade
0.1 1.3 REACTOME_SYNTHESIS_OF_VERY_LONG_CHAIN_FATTY_ACYL_COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 1.1 REACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 1.0 REACTOME_ABC_FAMILY_PROTEINS_MEDIATED_TRANSPORT Genes involved in ABC-family proteins mediated transport
0.1 0.9 REACTOME_ETHANOL_OXIDATION Genes involved in Ethanol oxidation
0.0 0.9 REACTOME_INTRINSIC_PATHWAY Genes involved in Intrinsic Pathway
0.0 0.9 REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.7 REACTOME_REGULATION_OF_IFNG_SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.5 REACTOME_PRESYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.5 REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.5 REACTOME_LYSOSOME_VESICLE_BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.4 REACTOME_MEMBRANE_BINDING_AND_TARGETTING_OF_GAG_PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.4 REACTOME_SYNTHESIS_OF_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.4 REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.3 REACTOME_XENOBIOTICS Genes involved in Xenobiotics
0.0 0.3 REACTOME_OTHER_SEMAPHORIN_INTERACTIONS Genes involved in Other semaphorin interactions