Motif ID: HOXA13

Z-value: 0.597


Transcription factors associated with HOXA13:

Gene SymbolEntrez IDGene Name
HOXA13 ENSG00000106031.6 HOXA13

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
HOXA13hg19_v2_chr7_-_27239703_27239725-0.472.1e-02Click!


Activity profile for motif HOXA13.

activity profile for motif HOXA13


Sorted Z-values histogram for motif HOXA13

Sorted Z-values for motif HOXA13



Network of associatons between targets according to the STRING database.



First level regulatory network of HOXA13

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_+_88117683 1.361 ENST00000369562.4
 C6ORF165
UPF0704 protein C6orf165
chr10_-_61513146 1.006 ENST00000430431.1
 LINC00948
long intergenic non-protein coding RNA 948
chrY_+_2709527 0.731 ENST00000250784.8
 RPS4Y1
ribosomal protein S4, Y-linked 1
chr10_-_61513201 0.715 ENST00000414264.1
ENST00000594536.1
 LINC00948

long intergenic non-protein coding RNA 948

chr11_-_114466477 0.618 ENST00000375478.3
 NXPE4
neurexophilin and PC-esterase domain family, member 4
chr10_-_28270795 0.611 ENST00000545014.1
 ARMC4
armadillo repeat containing 4
chr7_-_3214287 0.553 ENST00000404626.3
 AC091801.1
LOC392621; Uncharacterized protein
chr7_-_16921601 0.541 ENST00000402239.3
ENST00000310398.2
ENST00000414935.1
 AGR3


anterior gradient 3


chr4_-_147866960 0.532 ENST00000513335.1
 TTC29
tetratricopeptide repeat domain 29
chr7_-_69062391 0.462 ENST00000436600.2
 RP5-942I16.1
RP5-942I16.1
chr1_+_43766642 0.455 ENST00000372476.3
 TIE1
tyrosine kinase with immunoglobulin-like and EGF-like domains 1
chr7_+_23719749 0.424 ENST00000409192.3
ENST00000344962.4
ENST00000409653.1
ENST00000409994.3
 FAM221A



family with sequence similarity 221, member A



chr11_-_114466471 0.413 ENST00000424261.2
 NXPE4
neurexophilin and PC-esterase domain family, member 4
chrX_-_38186775 0.410 ENST00000339363.3
ENST00000309513.3
ENST00000338898.3
ENST00000342811.3
ENST00000378505.2
 RPGR




retinitis pigmentosa GTPase regulator




chr12_+_70219052 0.400 ENST00000552032.2
ENST00000547771.2
 MYRFL

myelin regulatory factor-like

chr14_-_102706934 0.376 ENST00000523231.1
ENST00000524370.1
ENST00000517966.1
 MOK


MOK protein kinase


chr1_+_47533160 0.360 ENST00000334194.3
 CYP4Z1
cytochrome P450, family 4, subfamily Z, polypeptide 1
chr15_+_71228826 0.355 ENST00000558456.1
ENST00000560158.2
ENST00000558808.1
ENST00000559806.1
ENST00000559069.1
 LRRC49




leucine rich repeat containing 49




chr17_-_15496722 0.343 ENST00000472534.1
 CDRT1
CMT1A duplicated region transcript 1
chr19_+_49496705 0.328 ENST00000595090.1
 RUVBL2
RuvB-like AAA ATPase 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 37 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 0.9 GO:0090202 transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
0.0 0.8 GO:0043486 histone exchange(GO:0043486)
0.1 0.7 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.0 0.6 GO:0003356 regulation of cilium beat frequency(GO:0003356)
0.1 0.5 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.0 0.5 GO:0045026 plasma membrane fusion(GO:0045026)
0.1 0.4 GO:0017186 peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase(GO:0017186)
0.1 0.4 GO:0097045 phosphatidylserine exposure on blood platelet(GO:0097045)
0.1 0.3 GO:0060830 intraciliary anterograde transport(GO:0035720) ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
0.0 0.3 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.0 0.3 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.3 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0 0.3 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.3 GO:0051764 actin crosslink formation(GO:0051764)
0.1 0.2 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.0 0.2 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.0 0.2 GO:0010902 positive regulation of very-low-density lipoprotein particle remodeling(GO:0010902)
0.0 0.2 GO:0006657 CDP-choline pathway(GO:0006657)
0.0 0.2 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.0 0.2 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)

Gene overrepresentation in cellular_component category:

Showing 1 to 19 of 19 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 0.9 GO:0097255 R2TP complex(GO:0097255)
0.0 0.9 GO:0097546 ciliary base(GO:0097546)
0.0 0.8 GO:0000812 Swr1 complex(GO:0000812)
0.1 0.3 GO:0030849 autosome(GO:0030849)
0.0 0.3 GO:0000439 core TFIIH complex(GO:0000439)
0.0 0.3 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 0.3 GO:0071953 elastic fiber(GO:0071953)
0.0 0.3 GO:0097512 cardiac myofibril(GO:0097512)
0.0 0.3 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.3 GO:0000242 pericentriolar material(GO:0000242)
0.1 0.2 GO:0000438 core TFIIH complex portion of holo TFIIH complex(GO:0000438)
0.0 0.1 GO:0043511 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.0 0.1 GO:0005663 DNA replication factor C complex(GO:0005663)
0.0 0.1 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.0 0.1 GO:0070847 core mediator complex(GO:0070847)
0.0 0.1 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.0 0.1 GO:0044530 supraspliceosomal complex(GO:0044530)
0.0 0.1 GO:0005675 holo TFIIH complex(GO:0005675)
0.0 0.1 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 31 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 0.9 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.0 0.8 GO:0019212 phosphatase inhibitor activity(GO:0019212)
0.1 0.6 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.5 GO:0002162 dystroglycan binding(GO:0002162)
0.1 0.4 GO:0016603 glutaminyl-peptide cyclotransferase activity(GO:0016603)
0.0 0.4 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.3 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.0 0.3 GO:0032395 MHC class II receptor activity(GO:0032395)
0.0 0.3 GO:0070330 aromatase activity(GO:0070330)
0.0 0.3 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.2 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.0 0.2 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.0 0.2 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.0 0.2 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 0.2 GO:0035473 lipase binding(GO:0035473) lipoprotein lipase activator activity(GO:0060230)
0.0 0.2 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.2 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.2 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 0.2 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 0.1 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)

Gene overrepresentation in C2:CP category:

Showing 1 to 3 of 3 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.9 PID_MYC_PATHWAY C-MYC pathway
0.0 0.8 PID_AURORA_B_PATHWAY Aurora B signaling
0.0 0.3 SA_G2_AND_M_PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 8 of 8 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.0 REACTOME_EXTENSION_OF_TELOMERES Genes involved in Extension of Telomeres
0.0 0.3 REACTOME_GLOBAL_GENOMIC_NER_GG_NER Genes involved in Global Genomic NER (GG-NER)
0.0 0.3 REACTOME_TRANSLOCATION_OF_ZAP_70_TO_IMMUNOLOGICAL_SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 0.3 REACTOME_CRMPS_IN_SEMA3A_SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.2 REACTOME_RECYCLING_OF_BILE_ACIDS_AND_SALTS Genes involved in Recycling of bile acids and salts
0.0 0.2 REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_PDH_COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.2 REACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.1 REACTOME_IRAK2_MEDIATED_ACTIVATION_OF_TAK1_COMPLEX_UPON_TLR7_8_OR_9_STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation