Motif ID: HOXA5

Z-value: 0.391


Transcription factors associated with HOXA5:

Gene SymbolEntrez IDGene Name
HOXA5 ENSG00000106004.4 HOXA5

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
HOXA5hg19_v2_chr7_-_27183263_27183287-0.242.5e-01Click!


Activity profile for motif HOXA5.

activity profile for motif HOXA5


Sorted Z-values histogram for motif HOXA5

Sorted Z-values for motif HOXA5



Network of associatons between targets according to the STRING database.



First level regulatory network of HOXA5

PNG image of the network

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Top targets:


Showing 1 to 20 of 166 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_+_130339710 0.860 ENST00000526087.1
ENST00000533560.1
ENST00000361794.2
 L3MBTL3


l(3)mbt-like 3 (Drosophila)


chr2_-_113594279 0.398 ENST00000416750.1
ENST00000418817.1
ENST00000263341.2
 IL1B


interleukin 1, beta


chrX_+_99899180 0.364 ENST00000373004.3
 SRPX2
sushi-repeat containing protein, X-linked 2
chr9_-_110251836 0.348 ENST00000374672.4
 KLF4
Kruppel-like factor 4 (gut)
chr5_-_87516448 0.311 ENST00000511218.1
 TMEM161B
transmembrane protein 161B
chr15_-_34628951 0.257 ENST00000397707.2
ENST00000560611.1
 SLC12A6

solute carrier family 12 (potassium/chloride transporter), member 6

chr1_+_87012753 0.255 ENST00000370563.3
 CLCA4
chloride channel accessory 4
chr7_-_23510086 0.246 ENST00000258729.3
 IGF2BP3
insulin-like growth factor 2 mRNA binding protein 3
chr4_+_74606223 0.245 ENST00000307407.3
ENST00000401931.1
 IL8

interleukin 8

chr1_+_84609944 0.236 ENST00000370685.3
 PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr4_+_71063641 0.231 ENST00000514097.1
 ODAM
odontogenic, ameloblast asssociated
chr2_+_102508955 0.203 ENST00000414004.2
 FLJ20373
FLJ20373
chr14_+_65878565 0.200 ENST00000556518.1
ENST00000557164.1
 FUT8

fucosyltransferase 8 (alpha (1,6) fucosyltransferase)

chr14_+_67291158 0.198 ENST00000555456.1
 GPHN
gephyrin
chr6_+_125304502 0.196 ENST00000519799.1
ENST00000368414.2
ENST00000359704.2
 RNF217


ring finger protein 217


chr3_+_130569429 0.184 ENST00000505330.1
ENST00000504381.1
ENST00000507488.2
ENST00000393221.4
 ATP2C1



ATPase, Ca++ transporting, type 2C, member 1



chr7_+_100136811 0.183 ENST00000300176.4
ENST00000262935.4
 AGFG2

ArfGAP with FG repeats 2

chr10_-_115904361 0.180 ENST00000428953.1
ENST00000543782.1
 C10orf118

chromosome 10 open reading frame 118

chr4_+_86525299 0.177 ENST00000512201.1
 ARHGAP24
Rho GTPase activating protein 24
chr6_-_32157947 0.171 ENST00000375050.4
 PBX2
pre-B-cell leukemia homeobox 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 32 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 0.9 GO:0043249 erythrocyte maturation(GO:0043249)
0.1 0.4 GO:0060557 positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
0.0 0.4 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.1 0.3 GO:0014740 negative regulation of muscle hyperplasia(GO:0014740)
0.1 0.3 GO:0071477 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.1 0.2 GO:0036071 N-glycan fucosylation(GO:0036071)
0.1 0.2 GO:0072579 molybdenum incorporation into molybdenum-molybdopterin complex(GO:0018315) metal incorporation into metallo-molybdopterin complex(GO:0042040) glycine receptor clustering(GO:0072579)
0.0 0.2 GO:1900138 negative regulation of phospholipase A2 activity(GO:1900138)
0.0 0.2 GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.0 0.2 GO:2000230 negative regulation of pancreatic stellate cell proliferation(GO:2000230)
0.0 0.2 GO:0097338 response to clozapine(GO:0097338)
0.0 0.2 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.0 0.2 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.0 0.2 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.0 0.1 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.0 0.1 GO:0039019 pronephric nephron development(GO:0039019)
0.0 0.1 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0 0.1 GO:0089700 protein kinase D signaling(GO:0089700)
0.0 0.1 GO:1990535 regulation of intracellular calcium activated chloride channel activity(GO:1902938) neuron projection maintenance(GO:1990535)
0.0 0.1 GO:1903215 negative regulation of protein targeting to mitochondrion(GO:1903215)

Gene overrepresentation in cellular_component category:

Showing 1 to 8 of 8 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 0.2 GO:0097679 other organism cytoplasm(GO:0097679)
0.0 0.2 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0 0.2 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.1 GO:0032173 septin ring(GO:0005940) septin collar(GO:0032173)
0.0 0.1 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.0 0.1 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.1 GO:0031313 extrinsic component of external side of plasma membrane(GO:0031232) extrinsic component of endosome membrane(GO:0031313)
0.0 0.0 GO:0034657 GID complex(GO:0034657)

Gene overrepresentation in molecular_function category:

Showing 1 to 17 of 17 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.4 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.1 0.3 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.0 0.3 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1 0.2 GO:0008424 glycoprotein 6-alpha-L-fucosyltransferase activity(GO:0008424) alpha-(1->6)-fucosyltransferase activity(GO:0046921)
0.1 0.2 GO:0061599 molybdopterin adenylyltransferase activity(GO:0061598) molybdopterin molybdotransferase activity(GO:0061599)
0.0 0.2 GO:0050692 DBD domain binding(GO:0050692)
0.0 0.2 GO:0000150 recombinase activity(GO:0000150)
0.0 0.2 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.1 GO:0098770 FBXO family protein binding(GO:0098770)
0.0 0.1 GO:0050528 acyloxyacyl hydrolase activity(GO:0050528)
0.0 0.1 GO:0005137 interleukin-5 receptor binding(GO:0005137)
0.0 0.1 GO:1903135 cupric ion binding(GO:1903135)
0.0 0.1 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 0.1 GO:0015307 drug:proton antiporter activity(GO:0015307)
0.0 0.1 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.1 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.1 GO:0001594 trace-amine receptor activity(GO:0001594)

Gene overrepresentation in C2:CP category:

Showing 1 to 1 of 1 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.4 PID_ANTHRAX_PATHWAY Cellular roles of Anthrax toxin

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 1 of 1 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.3 REACTOME_SYNTHESIS_SECRETION_AND_DEACYLATION_OF_GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin