Motif ID: HOXA9

Z-value: 0.549


Transcription factors associated with HOXA9:

Gene SymbolEntrez IDGene Name
HOXA9 ENSG00000078399.11 HOXA9

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
HOXA9hg19_v2_chr7_-_27205136_272051640.087.0e-01Click!


Activity profile for motif HOXA9.

activity profile for motif HOXA9


Sorted Z-values histogram for motif HOXA9

Sorted Z-values for motif HOXA9



Network of associatons between targets according to the STRING database.



First level regulatory network of HOXA9

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr16_-_55867146 1.417 ENST00000422046.2
 CES1
carboxylesterase 1
chr1_-_152131703 1.239 ENST00000316073.3
 RPTN
repetin
chr12_-_13248598 0.787 ENST00000337630.6
ENST00000545699.1
 GSG1

germ cell associated 1

chr16_-_67427389 0.731 ENST00000562206.1
ENST00000290942.5
ENST00000393957.2
 TPPP3


tubulin polymerization-promoting protein family member 3


chr3_-_197686847 0.641 ENST00000265239.6
 IQCG
IQ motif containing G
chr1_+_152956549 0.546 ENST00000307122.2
 SPRR1A
small proline-rich protein 1A
chr10_+_51549498 0.457 ENST00000358559.2
ENST00000298239.6
 MSMB

microseminoprotein, beta-

chrX_+_65384182 0.414 ENST00000441993.2
ENST00000419594.1
 HEPH

hephaestin

chr10_+_85933494 0.409 ENST00000372126.3
 C10orf99
chromosome 10 open reading frame 99
chr7_-_3214287 0.406 ENST00000404626.3
 AC091801.1
LOC392621; Uncharacterized protein
chr3_+_186353756 0.360 ENST00000431018.1
ENST00000450521.1
ENST00000539949.1
 FETUB


fetuin B


chr2_-_197226875 0.357 ENST00000409111.1
 HECW2
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2
chrX_+_144908928 0.349 ENST00000408967.2
 TMEM257
transmembrane protein 257
chr2_-_88427568 0.339 ENST00000393750.3
ENST00000295834.3
 FABP1

fatty acid binding protein 1, liver

chr3_+_148545586 0.333 ENST00000282957.4
ENST00000468341.1
 CPB1

carboxypeptidase B1 (tissue)

chrX_+_130192318 0.328 ENST00000370922.1
 ARHGAP36
Rho GTPase activating protein 36
chr11_+_101918153 0.315 ENST00000434758.2
ENST00000526781.1
ENST00000534360.1
 C11orf70


chromosome 11 open reading frame 70


chr21_-_28820892 0.310 ENST00000420186.2
 AP001604.3
AP001604.3
chr1_+_24645807 0.306 ENST00000361548.4
 GRHL3
grainyhead-like 3 (Drosophila)
chr4_-_34041504 0.303 ENST00000512581.1
ENST00000505018.1
 RP11-79E3.3

RP11-79E3.3


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 60 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.8 GO:0070268 cornification(GO:0070268)
0.4 1.4 GO:0090119 vesicle-mediated cholesterol transport(GO:0090119)
0.0 0.9 GO:0006825 copper ion transport(GO:0006825)
0.0 0.8 GO:0090179 planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.1 0.6 GO:0007288 sperm axoneme assembly(GO:0007288)
0.0 0.6 GO:0051923 sulfation(GO:0051923)
0.0 0.5 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.0 0.5 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.4 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.1 0.3 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.0 0.3 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.0 0.3 GO:0003334 keratinocyte development(GO:0003334)
0.1 0.2 GO:0007538 primary sex determination(GO:0007538)
0.0 0.2 GO:0060648 mammary gland bud morphogenesis(GO:0060648) regulation of determination of dorsal identity(GO:2000015)
0.0 0.2 GO:0032455 nerve growth factor processing(GO:0032455)
0.0 0.2 GO:0044026 DNA hypermethylation(GO:0044026)
0.0 0.2 GO:0048263 determination of dorsal identity(GO:0048263)
0.0 0.2 GO:0070309 lens fiber cell morphogenesis(GO:0070309)
0.0 0.2 GO:0051122 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.0 0.2 GO:0098967 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)

Gene overrepresentation in cellular_component category:

Showing 1 to 15 of 15 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.9 GO:0001533 cornified envelope(GO:0001533)
0.1 0.7 GO:0097427 microtubule bundle(GO:0097427)
0.1 0.6 GO:0002177 manchette(GO:0002177)
0.0 0.3 GO:0045179 apical cortex(GO:0045179)
0.0 0.2 GO:1990796 photoreceptor cell terminal bouton(GO:1990796)
0.0 0.1 GO:0034686 integrin alphav-beta8 complex(GO:0034686)
0.0 0.1 GO:0071065 alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065)
0.0 0.1 GO:0030849 autosome(GO:0030849)
0.0 0.1 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.0 0.1 GO:0001740 Barr body(GO:0001740)
0.0 0.1 GO:0000836 Hrd1p ubiquitin ligase complex(GO:0000836)
0.0 0.1 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.0 0.1 GO:0043219 lateral loop(GO:0043219)
0.0 0.1 GO:1990246 uniplex complex(GO:1990246)
0.0 0.1 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 42 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 1.4 GO:0047374 methylumbelliferyl-acetate deacetylase activity(GO:0047374)
0.1 0.9 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 0.8 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.8 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.8 GO:0070063 RNA polymerase binding(GO:0070063)
0.1 0.5 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.0 0.5 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.4 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.4 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.3 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.0 0.3 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.0 0.3 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.3 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.2 GO:0051120 hepoxilin A3 synthase activity(GO:0051120)
0.0 0.2 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.0 0.2 GO:0034875 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.0 0.2 GO:0098821 BMP receptor activity(GO:0098821)
0.0 0.2 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.0 0.2 GO:0050543 icosatetraenoic acid binding(GO:0050543) arachidonic acid binding(GO:0050544)
0.0 0.2 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)

Gene overrepresentation in C2:CP category:

Showing 1 to 1 of 1 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.4 SA_PROGRAMMED_CELL_DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 4 of 4 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.9 REACTOME_METAL_ION_SLC_TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.4 REACTOME_REGULATION_OF_IFNA_SIGNALING Genes involved in Regulation of IFNA signaling
0.0 0.3 REACTOME_XENOBIOTICS Genes involved in Xenobiotics
0.0 0.3 REACTOME_CYTOSOLIC_SULFONATION_OF_SMALL_MOLECULES Genes involved in Cytosolic sulfonation of small molecules