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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr10_-_105845674	3.548	ENST00000353479.5 ENST00000369733.3	COL17A1	collagen, type XVII, alpha 1
chr4_-_39033963	3.046	ENST00000381938.3	TMEM156	transmembrane protein 156
chr11_-_107729887	2.841	ENST00000525815.1	SLC35F2	solute carrier family 35, member F2
chr2_+_102953608	2.641	ENST00000311734.2 ENST00000409584.1	IL1RL1	interleukin 1 receptor-like 1
chr10_+_6779326	2.561	ENST00000417112.1	RP11-554I8.2	RP11-554I8.2
chr2_-_161056762	2.544	ENST00000428609.2 ENST00000409967.2	ITGB6	integrin, beta 6
chr12_-_10978957	2.335	ENST00000240619.2	TAS2R10	taste receptor, type 2, member 10
chr9_+_125133315	2.202	ENST00000223423.4 ENST00000362012.2	PTGS1	prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr2_-_161056802	2.163	ENST00000283249.2 ENST00000409872.1	ITGB6	integrin, beta 6
chr12_-_8803128	2.160	ENST00000543467.1	MFAP5	microfibrillar associated protein 5
chr19_-_36001113	2.151	ENST00000434389.1	DMKN	dermokine
chr11_+_33061543	2.034	ENST00000432887.1 ENST00000528898.1 ENST00000531632.2	TCP11L1	t-complex 11, testis-specific-like 1
chrX_+_43515467	1.890	ENST00000338702.3 ENST00000542639.1	MAOA	monoamine oxidase A
chr12_-_10022735	1.852	ENST00000228438.2	CLEC2B	C-type lectin domain family 2, member B
chr4_+_86525299	1.741	ENST00000512201.1	ARHGAP24	Rho GTPase activating protein 24
chr7_+_134528635	1.690	ENST00000445569.2	CALD1	caldesmon 1
chr16_-_30122717	1.638	ENST00000566613.1	GDPD3	glycerophosphodiester phosphodiesterase domain containing 3
chr18_+_29027696	1.627	ENST00000257189.4	DSG3	desmoglein 3
chr3_-_149095652	1.608	ENST00000305366.3	TM4SF1	transmembrane 4 L six family member 1
chr4_-_57547870	1.595	ENST00000381260.3 ENST00000420433.1 ENST00000554144.1 ENST00000557328.1	HOPX	HOP homeobox
chr11_-_121986923	1.587	ENST00000560104.1	BLID	BH3-like motif containing, cell death inducer
chr4_-_159956333	1.575	ENST00000434826.2	C4orf45	chromosome 4 open reading frame 45
chr9_-_95640218	1.556	ENST00000395506.3 ENST00000375495.3 ENST00000332591.6	ZNF484	zinc finger protein 484
chr9_+_125132803	1.440	ENST00000540753.1	PTGS1	prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr6_+_130339710	1.438	ENST00000526087.1 ENST00000533560.1 ENST00000361794.2	L3MBTL3	l(3)mbt-like 3 (Drosophila)
chr2_+_90211643	1.425	ENST00000390277.2	IGKV3D-11	immunoglobulin kappa variable 3D-11
chr1_+_62439037	1.375	ENST00000545929.1	INADL	InaD-like (Drosophila)
chr8_-_125577940	1.331	ENST00000519168.1 ENST00000395508.2	MTSS1	metastasis suppressor 1
chr9_-_77567743	1.280	ENST00000376854.5	C9orf40	chromosome 9 open reading frame 40
chr2_+_182850743	1.276	ENST00000409702.1	PPP1R1C	protein phosphatase 1, regulatory (inhibitor) subunit 1C
chr14_-_67878917	1.228	ENST00000216446.4	PLEK2	pleckstrin 2
chr7_-_107642348	1.208	ENST00000393561.1	LAMB1	laminin, beta 1
chr1_-_197115818	1.199	ENST00000367409.4 ENST00000294732.7	ASPM	asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
chr12_-_22063787	1.198	ENST00000544039.1	ABCC9	ATP-binding cassette, sub-family C (CFTR/MRP), member 9
chr4_-_39979576	1.155	ENST00000303538.8 ENST00000503396.1	PDS5A	PDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae)
chr9_+_124329336	1.140	ENST00000394340.3 ENST00000436835.1 ENST00000259371.2	DAB2IP	DAB2 interacting protein
chr2_+_102456277	1.106	ENST00000421882.1	MAP4K4	mitogen-activated protein kinase kinase kinase kinase 4
chr18_+_21452964	1.096	ENST00000587184.1	LAMA3	laminin, alpha 3
chr6_+_42584847	1.091	ENST00000372883.3	UBR2	ubiquitin protein ligase E3 component n-recognin 2
chr14_+_56584414	1.085	ENST00000559044.1	PELI2	pellino E3 ubiquitin protein ligase family member 2
chr4_-_109541539	1.060	ENST00000509984.1 ENST00000507248.1 ENST00000506795.1	RPL34-AS1	RPL34 antisense RNA 1 (head to head)
chr11_-_55703876	1.050	ENST00000301532.3	OR5I1	olfactory receptor, family 5, subfamily I, member 1
chr6_+_114178512	0.987	ENST00000368635.4	MARCKS	myristoylated alanine-rich protein kinase C substrate
chr4_+_169418255	0.974	ENST00000505667.1 ENST00000511948.1	PALLD	palladin, cytoskeletal associated protein
chr2_-_40680578	0.962	ENST00000455476.1	SLC8A1	solute carrier family 8 (sodium/calcium exchanger), member 1
chr7_+_107224364	0.958	ENST00000491150.1	BCAP29	B-cell receptor-associated protein 29
chr2_+_90273679	0.947	ENST00000423080.2	IGKV3D-7	immunoglobulin kappa variable 3D-7
chr18_+_21452804	0.943	ENST00000269217.6	LAMA3	laminin, alpha 3
chr6_+_34204642	0.932	ENST00000347617.6 ENST00000401473.3 ENST00000311487.5 ENST00000447654.1 ENST00000395004.3	HMGA1	high mobility group AT-hook 1
chr15_+_67418047	0.901	ENST00000540846.2	SMAD3	SMAD family member 3
chr2_+_90077680	0.898	ENST00000390270.2	IGKV3D-20	immunoglobulin kappa variable 3D-20
chr14_+_31046959	0.875	ENST00000547532.1 ENST00000555429.1	G2E3	G2/M-phase specific E3 ubiquitin protein ligase
chr12_+_26348429	0.868	ENST00000242729.2	SSPN	sarcospan
chr12_+_26348246	0.865	ENST00000422622.2	SSPN	sarcospan
chr5_+_89770664	0.862	ENST00000503973.1 ENST00000399107.1	POLR3G	polymerase (RNA) III (DNA directed) polypeptide G (32kD)
chr11_+_35201826	0.854	ENST00000531873.1	CD44	CD44 molecule (Indian blood group)
chr5_+_89770696	0.837	ENST00000504930.1 ENST00000514483.1	POLR3G	polymerase (RNA) III (DNA directed) polypeptide G (32kD)
chr12_+_26348582	0.824	ENST00000535504.1	SSPN	sarcospan
chrX_-_77225135	0.821	ENST00000458128.1	PGAM4	phosphoglycerate mutase family member 4
chr14_-_106494587	0.794	ENST00000390597.2	IGHV2-5	immunoglobulin heavy variable 2-5
chr17_+_33914460	0.793	ENST00000537622.2	AP2B1	adaptor-related protein complex 2, beta 1 subunit
chr22_+_46476192	0.787	ENST00000443490.1	FLJ27365	hsa-mir-4763
chr20_-_56265680	0.785	ENST00000414037.1	PMEPA1	prostate transmembrane protein, androgen induced 1
chr6_-_82957433	0.782	ENST00000306270.7	IBTK	inhibitor of Bruton agammaglobulinemia tyrosine kinase
chr2_-_89327228	0.766	ENST00000483158.1	IGKV3-11	immunoglobulin kappa variable 3-11
chr14_+_24641062	0.762	ENST00000311457.3 ENST00000557806.1 ENST00000559919.1	REC8	REC8 meiotic recombination protein
chr17_-_45266542	0.760	ENST00000531206.1 ENST00000527547.1 ENST00000446365.2 ENST00000575483.1 ENST00000066544.3	CDC27	cell division cycle 27
chr6_+_47749718	0.757	ENST00000489301.2 ENST00000371211.2 ENST00000393699.2	OPN5	opsin 5
chr15_+_94899183	0.748	ENST00000557742.1	MCTP2	multiple C2 domains, transmembrane 2
chr4_-_120243545	0.725	ENST00000274024.3	FABP2	fatty acid binding protein 2, intestinal
chr7_+_134430212	0.723	ENST00000436461.2	CALD1	caldesmon 1
chr1_+_152784447	0.712	ENST00000360090.3	LCE1B	late cornified envelope 1B
chr10_+_18549645	0.709	ENST00000396576.2	CACNB2	calcium channel, voltage-dependent, beta 2 subunit
chr11_-_104827425	0.696	ENST00000393150.3	CASP4	caspase 4, apoptosis-related cysteine peptidase
chr11_-_5323226	0.696	ENST00000380224.1	OR51B4	olfactory receptor, family 51, subfamily B, member 4
chr17_-_39743139	0.674	ENST00000167586.6	KRT14	keratin 14
chrX_-_100662881	0.654	ENST00000218516.3	GLA	galactosidase, alpha
chrX_+_44703249	0.644	ENST00000339042.4	DUSP21	dual specificity phosphatase 21
chr11_+_133938820	0.640	ENST00000299106.4 ENST00000529443.2	JAM3	junctional adhesion molecule 3
chr2_-_89385283	0.640	ENST00000390252.2	IGKV3-15	immunoglobulin kappa variable 3-15
chr17_-_57229155	0.638	ENST00000584089.1	SKA2	spindle and kinetochore associated complex subunit 2
chrX_-_18690210	0.636	ENST00000379984.3	RS1	retinoschisin 1
chr4_-_103997862	0.631	ENST00000394785.3	SLC9B2	solute carrier family 9, subfamily B (NHA2, cation proton antiporter 2), member 2
chr20_+_30697298	0.625	ENST00000398022.2	TM9SF4	transmembrane 9 superfamily protein member 4
chr7_-_144435985	0.623	ENST00000549981.1	TPK1	thiamin pyrophosphokinase 1
chr2_+_182850551	0.622	ENST00000452904.1 ENST00000409137.3 ENST00000280295.3	PPP1R1C	protein phosphatase 1, regulatory (inhibitor) subunit 1C
chr7_-_87342564	0.619	ENST00000265724.3 ENST00000416177.1	ABCB1	ATP-binding cassette, sub-family B (MDR/TAP), member 1
chr5_-_125930929	0.616	ENST00000553117.1 ENST00000447989.2 ENST00000409134.3	ALDH7A1	aldehyde dehydrogenase 7 family, member A1
chr5_+_57787254	0.616	ENST00000502276.1 ENST00000396776.2 ENST00000511930.1	GAPT	GRB2-binding adaptor protein, transmembrane
chr1_+_155278625	0.615	ENST00000368356.4 ENST00000356657.6	FDPS	farnesyl diphosphate synthase
chr1_+_225600404	0.611	ENST00000366845.2	AC092811.1	AC092811.1
chr3_-_20053741	0.602	ENST00000389050.4	PP2D1	protein phosphatase 2C-like domain containing 1
chr19_-_3557570	0.601	ENST00000355415.2	MFSD12	major facilitator superfamily domain containing 12
chr13_-_24007815	0.598	ENST00000382298.3	SACS	spastic ataxia of Charlevoix-Saguenay (sacsin)
chr2_-_130031335	0.587	ENST00000375987.3	AC079586.1	AC079586.1
chr1_-_211307404	0.586	ENST00000367007.4	KCNH1	potassium voltage-gated channel, subfamily H (eag-related), member 1
chr1_+_115572415	0.582	ENST00000256592.1	TSHB	thyroid stimulating hormone, beta
chr1_+_155278539	0.576	ENST00000447866.1	FDPS	farnesyl diphosphate synthase
chr14_+_35591858	0.570	ENST00000603544.1	KIAA0391	KIAA0391
chr14_+_22670455	0.567	ENST00000390460.1	TRAV26-2	T cell receptor alpha variable 26-2
chr11_+_55594695	0.566	ENST00000378397.1	OR5L2	olfactory receptor, family 5, subfamily L, member 2
chr6_+_29079668	0.564	ENST00000377169.1	OR2J3	olfactory receptor, family 2, subfamily J, member 3
chrX_-_71458802	0.552	ENST00000373657.1 ENST00000334463.3	ERCC6L	excision repair cross-complementing rodent repair deficiency, complementation group 6-like
chr1_-_201140673	0.548	ENST00000367333.2	TMEM9	transmembrane protein 9
chr8_-_42623747	0.541	ENST00000534622.1	CHRNA6	cholinergic receptor, nicotinic, alpha 6 (neuronal)
chr4_-_90757364	0.539	ENST00000508895.1	SNCA	synuclein, alpha (non A4 component of amyloid precursor)
chr2_-_88285309	0.537	ENST00000420840.2	RGPD2	RANBP2-like and GRIP domain containing 2
chr14_+_103851712	0.531	ENST00000440884.3 ENST00000416682.2 ENST00000429436.2 ENST00000303622.9	MARK3	MAP/microtubule affinity-regulating kinase 3
chr2_+_219472488	0.527	ENST00000450993.2	PLCD4	phospholipase C, delta 4
chr2_+_234637754	0.524	ENST00000609767.1 ENST00000482026.1	UGT1A1 UGT1A3	UDP glucuronosyltransferase 1 family, polypeptide A8 UDP glucuronosyltransferase 1 family, polypeptide A3
chr4_-_185275104	0.523	ENST00000317596.3	RP11-290F5.2	RP11-290F5.2
chr18_-_24443151	0.521	ENST00000440832.3	AQP4	aquaporin 4
chr14_-_106552755	0.521	ENST00000390600.2	IGHV3-9	immunoglobulin heavy variable 3-9
chr4_-_69111401	0.519	ENST00000332644.5	TMPRSS11B	transmembrane protease, serine 11B
chr1_-_67266939	0.518	ENST00000304526.2	INSL5	insulin-like 5
chr11_-_14913190	0.518	ENST00000532378.1	CYP2R1	cytochrome P450, family 2, subfamily R, polypeptide 1
chr4_+_72897521	0.517	ENST00000308744.6 ENST00000344413.5	NPFFR2	neuropeptide FF receptor 2
chr10_+_696000	0.515	ENST00000381489.5	PRR26	proline rich 26
chr3_-_185538849	0.503	ENST00000421047.2	IGF2BP2	insulin-like growth factor 2 mRNA binding protein 2
chr13_+_32313658	0.502	ENST00000380314.1 ENST00000298386.2	RXFP2	relaxin/insulin-like family peptide receptor 2
chr17_+_33914276	0.499	ENST00000592545.1 ENST00000538556.1 ENST00000312678.8 ENST00000589344.1	AP2B1	adaptor-related protein complex 2, beta 1 subunit
chrX_+_37639302	0.486	ENST00000545017.1 ENST00000536160.1	CYBB	cytochrome b-245, beta polypeptide
chr3_+_139063372	0.478	ENST00000478464.1	MRPS22	mitochondrial ribosomal protein S22
chr14_-_106668095	0.461	ENST00000390606.2	IGHV3-20	immunoglobulin heavy variable 3-20
chr4_-_103749205	0.461	ENST00000508249.1	UBE2D3	ubiquitin-conjugating enzyme E2D 3
chr19_-_36304201	0.460	ENST00000301175.3	PRODH2	proline dehydrogenase (oxidase) 2
chr4_-_103749179	0.457	ENST00000502690.1	UBE2D3	ubiquitin-conjugating enzyme E2D 3
chr5_-_16916624	0.446	ENST00000513882.1	MYO10	myosin X
chr12_+_8309630	0.444	ENST00000396570.3	ZNF705A	zinc finger protein 705A
chr8_-_49833978	0.441	ENST00000020945.1	SNAI2	snail family zinc finger 2
chr17_+_39394250	0.441	ENST00000254072.6	KRTAP9-8	keratin associated protein 9-8
chr4_+_169552748	0.437	ENST00000504519.1 ENST00000512127.1	PALLD	palladin, cytoskeletal associated protein
chr15_-_20193370	0.432	ENST00000558565.2	IGHV3OR15-7	immunoglobulin heavy variable 3/OR15-7 (pseudogene)
chr2_+_90248739	0.432	ENST00000468879.1	IGKV1D-43	immunoglobulin kappa variable 1D-43
chr18_-_44181442	0.427	ENST00000398722.4	LOXHD1	lipoxygenase homology domains 1
chr7_+_115862858	0.420	ENST00000393481.2	TES	testis derived transcript (3 LIM domains)
chr15_-_91565743	0.416	ENST00000535843.1	VPS33B	vacuolar protein sorting 33 homolog B (yeast)
chrX_+_13671225	0.410	ENST00000545566.1 ENST00000544987.1 ENST00000314720.4	TCEANC	transcription elongation factor A (SII) N-terminal and central domain containing
chr14_-_72458326	0.408	ENST00000542853.1	AC005477.1	AC005477.1
chr14_-_107049312	0.399	ENST00000390627.2	IGHV3-53	immunoglobulin heavy variable 3-53
chr1_-_198509804	0.396	ENST00000489986.1 ENST00000367382.1	ATP6V1G3	ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G3
chr15_+_66679155	0.394	ENST00000307102.5	MAP2K1	mitogen-activated protein kinase kinase 1
chr3_-_164796269	0.393	ENST00000264382.3	SI	sucrase-isomaltase (alpha-glucosidase)
chr4_+_71091786	0.392	ENST00000317987.5	FDCSP	follicular dendritic cell secreted protein
chrX_+_7137475	0.390	ENST00000217961.4	STS	steroid sulfatase (microsomal), isozyme S
chr10_-_58120996	0.389	ENST00000361148.6 ENST00000395405.1 ENST00000373944.3	ZWINT	ZW10 interacting kinetochore protein
chrX_-_100872911	0.388	ENST00000361910.4 ENST00000539247.1 ENST00000538627.1	ARMCX6	armadillo repeat containing, X-linked 6
chr7_-_111032971	0.387	ENST00000450877.1	IMMP2L	IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae)
chr15_-_25823938	0.385	ENST00000422117.1	AC124997.1	AC124997.1
chr11_+_89764274	0.385	ENST00000448984.1 ENST00000432771.1	TRIM49C	tripartite motif containing 49C
chr14_-_39639523	0.384	ENST00000330149.5 ENST00000554018.1 ENST00000347691.5	TRAPPC6B	trafficking protein particle complex 6B
chr14_-_51027838	0.383	ENST00000555216.1	MAP4K5	mitogen-activated protein kinase kinase kinase kinase 5
chr1_+_157963063	0.374	ENST00000360089.4 ENST00000368173.3 ENST00000392272.2	KIRREL	kin of IRRE like (Drosophila)
chr6_+_129204337	0.370	ENST00000421865.2	LAMA2	laminin, alpha 2
chr15_-_91565770	0.370	ENST00000535906.1 ENST00000333371.3	VPS33B	vacuolar protein sorting 33 homolog B (yeast)
chr8_-_49834299	0.368	ENST00000396822.1	SNAI2	snail family zinc finger 2
chr10_+_5135981	0.367	ENST00000380554.3	AKR1C3	aldo-keto reductase family 1, member C3
chr5_+_66300446	0.366	ENST00000261569.7	MAST4	microtubule associated serine/threonine kinase family member 4
chr8_-_30670384	0.365	ENST00000221138.4 ENST00000518243.1	PPP2CB	protein phosphatase 2, catalytic subunit, beta isozyme
chr11_-_117186946	0.363	ENST00000313005.6 ENST00000528053.1	BACE1	beta-site APP-cleaving enzyme 1
chrX_+_1710484	0.362	ENST00000313871.3 ENST00000381261.3	AKAP17A	A kinase (PRKA) anchor protein 17A
chr2_-_89292422	0.359	ENST00000495489.1	IGKV1-8	immunoglobulin kappa variable 1-8
chr2_+_87565634	0.358	ENST00000421835.2	IGKV3OR2-268	immunoglobulin kappa variable 3/OR2-268 (non-functional)
chr19_-_44388116	0.353	ENST00000587539.1	ZNF404	zinc finger protein 404
chr4_-_119759795	0.351	ENST00000419654.2	SEC24D	SEC24 family member D
chrX_+_153533275	0.351	ENST00000426989.1 ENST00000426203.1 ENST00000369912.2	TKTL1	transketolase-like 1
chr2_-_90538397	0.348	ENST00000443397.3	RP11-685N3.1	Uncharacterized protein
chr1_+_161691353	0.346	ENST00000367948.2	FCRLB	Fc receptor-like B
chr14_+_35591928	0.345	ENST00000605870.1 ENST00000557404.3	KIAA0391	KIAA0391
chr3_+_111718173	0.341	ENST00000494932.1	TAGLN3	transgelin 3
chr4_+_119810134	0.339	ENST00000434046.2	SYNPO2	synaptopodin 2
chr17_-_72772462	0.338	ENST00000582870.1 ENST00000581136.1 ENST00000357814.3 ENST00000579218.1 ENST00000583476.1 ENST00000580301.1 ENST00000583757.1 ENST00000582524.1	NAT9	N-acetyltransferase 9 (GCN5-related, putative)
chr20_-_33735070	0.334	ENST00000374491.3 ENST00000542871.1 ENST00000374492.3	EDEM2	ER degradation enhancer, mannosidase alpha-like 2
chr2_-_101925055	0.332	ENST00000295317.3	RNF149	ring finger protein 149
chr2_-_225811747	0.330	ENST00000409592.3	DOCK10	dedicator of cytokinesis 10
chr9_-_77643307	0.330	ENST00000376834.3 ENST00000376830.3	C9orf41	chromosome 9 open reading frame 41
chr20_-_1447467	0.329	ENST00000353088.2 ENST00000350991.4	NSFL1C	NSFL1 (p97) cofactor (p47)
chr4_+_169418195	0.326	ENST00000261509.6 ENST00000335742.7	PALLD	palladin, cytoskeletal associated protein
chr18_-_51751132	0.325	ENST00000256429.3	MBD2	methyl-CpG binding domain protein 2
chrX_+_120181457	0.321	ENST00000328078.1	GLUD2	glutamate dehydrogenase 2
chr14_+_35591735	0.321	ENST00000604948.1 ENST00000605201.1 ENST00000250377.7 ENST00000321130.10 ENST00000534898.4	KIAA0391	KIAA0391
chr7_+_23145884	0.314	ENST00000409689.1 ENST00000410047.1	KLHL7	kelch-like family member 7
chr2_-_15701422	0.313	ENST00000441750.1 ENST00000281513.5	NBAS	neuroblastoma amplified sequence
chr7_+_141438118	0.311	ENST00000265304.6 ENST00000498107.1 ENST00000467681.1 ENST00000465582.1 ENST00000463093.1	SSBP1	single-stranded DNA binding protein 1, mitochondrial
chr15_+_75970672	0.311	ENST00000435356.1	AC105020.1	Uncharacterized protein; cDNA FLJ12988 fis, clone NT2RP3000080
chr4_-_103749313	0.310	ENST00000394803.5	UBE2D3	ubiquitin-conjugating enzyme E2D 3
chr18_-_48346298	0.306	ENST00000398439.3	MRO	maestro
chr5_-_176889381	0.305	ENST00000393563.4 ENST00000512501.1	DBN1	drebrin 1
chrX_-_21676442	0.304	ENST00000379499.2	KLHL34	kelch-like family member 34
chr13_-_36050819	0.303	ENST00000379919.4	MAB21L1	mab-21-like 1 (C. elegans)
chr7_-_44580861	0.302	ENST00000546276.1 ENST00000289547.4 ENST00000381160.3 ENST00000423141.1	NPC1L1	NPC1-like 1
chr8_+_7783859	0.300	ENST00000400120.3	ZNF705B	zinc finger protein 705B
chr6_+_29429217	0.299	ENST00000396792.2	OR2H1	olfactory receptor, family 2, subfamily H, member 1
chr8_-_41166953	0.297	ENST00000220772.3	SFRP1	secreted frizzled-related protein 1
chr20_-_29978286	0.297	ENST00000376315.2	DEFB119	defensin, beta 119
chr6_-_38670897	0.297	ENST00000373365.4	GLO1	glyoxalase I
chr1_+_192605252	0.293	ENST00000391995.2 ENST00000543215.1	RGS13	regulator of G-protein signaling 13
chr6_+_43395272	0.287	ENST00000372530.4	ABCC10	ATP-binding cassette, sub-family C (CFTR/MRP), member 10
chr5_+_36152179	0.287	ENST00000508514.1 ENST00000513151.1 ENST00000546211.1	SKP2	S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
chr22_-_32766972	0.286	ENST00000382084.4 ENST00000382086.2	RFPL3S	RFPL3 antisense

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	2.6	GO:0038172	interleukin-33-mediated signaling pathway(GO:0038172)
0.4	4.7	GO:0038044	transforming growth factor-beta secretion(GO:0038044)
0.4	1.2	GO:0009786	regulation of asymmetric cell division(GO:0009786)
0.4	2.2	GO:1903575	cornified envelope assembly(GO:1903575)
0.3	1.2	GO:0021812	neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.3	0.8	GO:0070563	negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.3	1.3	GO:0099590	neurotransmitter receptor internalization(GO:0099590)
0.2	1.2	GO:0033384	geranyl diphosphate metabolic process(GO:0033383) geranyl diphosphate biosynthetic process(GO:0033384) farnesyl diphosphate biosynthetic process(GO:0045337)
0.2	1.1	GO:0036324	vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324) negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.2	4.0	GO:0019371	cyclooxygenase pathway(GO:0019371)
0.2	1.3	GO:0030035	microspike assembly(GO:0030035)
0.2	1.1	GO:0071596	ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.2	6.3	GO:0031581	hemidesmosome assembly(GO:0031581)
0.2	0.6	GO:0019285	glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456)
0.2	0.8	GO:0043456	regulation of pentose-phosphate shunt(GO:0043456)
0.2	0.9	GO:0090402	oncogene-induced cell senescence(GO:0090402)
0.2	1.1	GO:0008063	Toll signaling pathway(GO:0008063)
0.2	0.9	GO:0061767	negative regulation of lung blood pressure(GO:0061767)
0.2	0.6	GO:0042357	thiamine diphosphate metabolic process(GO:0042357)
0.1	0.7	GO:0071460	cellular response to cell-matrix adhesion(GO:0071460)
0.1	0.7	GO:1904844	response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.1	1.2	GO:0090646	mitochondrial tRNA processing(GO:0090646)
0.1	0.8	GO:0070889	platelet alpha granule organization(GO:0070889)
0.1	0.5	GO:0036378	calcitriol biosynthetic process from calciol(GO:0036378)
0.1	0.4	GO:0061300	cerebellum vasculature development(GO:0061300)
0.1	0.6	GO:0002322	B cell proliferation involved in immune response(GO:0002322)
0.1	1.4	GO:0043249	erythrocyte maturation(GO:0043249)
0.1	0.7	GO:1904879	positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.1	1.9	GO:0042420	dopamine catabolic process(GO:0042420)
0.1	0.9	GO:2001206	positive regulation of osteoclast development(GO:2001206)
0.1	0.3	GO:0036512	trimming of terminal mannose on B branch(GO:0036509) trimming of first mannose on A branch(GO:0036511) trimming of second mannose on A branch(GO:0036512)
0.1	0.5	GO:1903285	negative regulation of synaptic transmission, dopaminergic(GO:0032227) negative regulation of catecholamine metabolic process(GO:0045914) negative regulation of dopamine metabolic process(GO:0045963) negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470)
0.1	0.9	GO:1900623	regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.1	0.5	GO:0070980	biphenyl catabolic process(GO:0070980)
0.1	0.3	GO:1904956	neural crest cell fate commitment(GO:0014034) regulation of midbrain dopaminergic neuron differentiation(GO:1904956) regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000053)
0.1	1.0	GO:0098735	positive regulation of the force of heart contraction(GO:0098735)
0.1	1.0	GO:0070973	protein localization to endoplasmic reticulum exit site(GO:0070973)
0.1	0.6	GO:1901529	positive regulation of anion channel activity(GO:1901529)
0.1	0.4	GO:0006772	thiamine metabolic process(GO:0006772)
0.1	0.5	GO:0010133	proline catabolic process to glutamate(GO:0010133)
0.1	1.7	GO:0003334	keratinocyte development(GO:0003334)
0.1	0.7	GO:0002318	myeloid progenitor cell differentiation(GO:0002318)
0.1	0.3	GO:0050712	negative regulation of interleukin-1 alpha production(GO:0032690) negative regulation of interleukin-1 alpha secretion(GO:0050712)
0.1	0.4	GO:0090170	regulation of Golgi inheritance(GO:0090170)
0.1	0.7	GO:0046477	glycosylceramide catabolic process(GO:0046477)
0.1	0.7	GO:1903265	positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.1	0.4	GO:0090063	positive regulation of microtubule nucleation(GO:0090063)
0.1	0.3	GO:0010643	cell communication by chemical coupling(GO:0010643)
0.1	0.8	GO:0010991	negative regulation of SMAD protein complex assembly(GO:0010991)
0.1	0.6	GO:0000160	phosphorelay signal transduction system(GO:0000160)
0.1	2.3	GO:0001580	detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.1	0.5	GO:2000253	positive regulation of feeding behavior(GO:2000253)
0.1	1.5	GO:0000185	activation of MAPKKK activity(GO:0000185)
0.1	1.6	GO:0001829	trophectodermal cell differentiation(GO:0001829)
0.1	0.4	GO:0044245	polysaccharide digestion(GO:0044245)
0.1	0.2	GO:0039534	negative regulation of MDA-5 signaling pathway(GO:0039534)
0.1	0.3	GO:0061107	seminal vesicle development(GO:0061107)
0.1	1.2	GO:0007064	mitotic sister chromatid cohesion(GO:0007064)
0.1	2.2	GO:0060216	definitive hemopoiesis(GO:0060216)
0.1	0.8	GO:0072520	seminiferous tubule development(GO:0072520)
0.1	0.2	GO:1902626	assembly of large subunit precursor of preribosome(GO:1902626)
0.0	0.1	GO:0070432	regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070432)
0.0	0.5	GO:0035331	negative regulation of hippo signaling(GO:0035331)
0.0	0.6	GO:0070863	positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.0	1.7	GO:0006359	regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.0	0.3	GO:0006537	glutamate biosynthetic process(GO:0006537)
0.0	0.4	GO:0060665	regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.0	1.9	GO:1900087	positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.0	0.3	GO:1904381	Golgi apparatus mannose trimming(GO:1904381)
0.0	0.2	GO:2001271	negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0	0.3	GO:1902261	positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.0	0.2	GO:0010387	COP9 signalosome assembly(GO:0010387)
0.0	1.0	GO:0051764	actin crosslink formation(GO:0051764)
0.0	0.2	GO:0098967	exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.0	0.6	GO:0090084	negative regulation of inclusion body assembly(GO:0090084)
0.0	0.4	GO:0032224	positive regulation of synaptic transmission, cholinergic(GO:0032224)
0.0	2.0	GO:0070979	protein K11-linked ubiquitination(GO:0070979)
0.0	0.3	GO:2000622	regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0	0.1	GO:0002476	antigen processing and presentation of endogenous peptide antigen via MHC class Ib(GO:0002476)
0.0	0.6	GO:0009642	response to light intensity(GO:0009642)
0.0	0.1	GO:0006422	aspartyl-tRNA aminoacylation(GO:0006422)
0.0	0.3	GO:0009438	methylglyoxal metabolic process(GO:0009438)
0.0	5.0	GO:0006958	complement activation, classical pathway(GO:0006958)
0.0	0.6	GO:0018298	protein-chromophore linkage(GO:0018298)
0.0	0.3	GO:0051096	positive regulation of helicase activity(GO:0051096)
0.0	3.0	GO:0050911	detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0	0.3	GO:0030091	protein repair(GO:0030091)
0.0	0.2	GO:0052551	response to defense-related nitric oxide production by other organism involved in symbiotic interaction(GO:0052551) response to defense-related host nitric oxide production(GO:0052565)
0.0	0.2	GO:0006041	glucosamine metabolic process(GO:0006041)
0.0	0.1	GO:0006203	dGTP catabolic process(GO:0006203)
0.0	0.1	GO:0060748	tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.0	0.2	GO:0014717	regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014717) satellite cell activation involved in skeletal muscle regeneration(GO:0014901)
0.0	0.5	GO:0007252	I-kappaB phosphorylation(GO:0007252)
0.0	1.2	GO:0010107	potassium ion import(GO:0010107)
0.0	0.3	GO:0002315	marginal zone B cell differentiation(GO:0002315)
0.0	0.7	GO:0000042	protein targeting to Golgi(GO:0000042)
0.0	0.3	GO:0061303	cornea development in camera-type eye(GO:0061303)
0.0	0.1	GO:0030950	establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.0	0.2	GO:1900112	regulation of histone H3-K9 trimethylation(GO:1900112)
0.0	0.5	GO:0006833	water transport(GO:0006833)
0.0	0.6	GO:2000479	regulation of cAMP-dependent protein kinase activity(GO:2000479)
0.0	0.6	GO:0033189	response to vitamin A(GO:0033189)
0.0	0.1	GO:0003162	atrioventricular node development(GO:0003162)
0.0	0.1	GO:1903674	regulation of cap-dependent translational initiation(GO:1903674) positive regulation of cap-dependent translational initiation(GO:1903676)
0.0	0.1	GO:0006210	pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.0	0.9	GO:0019433	triglyceride catabolic process(GO:0019433)
0.0	0.1	GO:0002767	immune response-inhibiting cell surface receptor signaling pathway(GO:0002767)
0.0	0.1	GO:0046338	phosphatidylethanolamine catabolic process(GO:0046338)
0.0	0.4	GO:0090110	cargo loading into COPII-coated vesicle(GO:0090110)
0.0	0.1	GO:0031914	negative regulation of synaptic plasticity(GO:0031914)
0.0	0.2	GO:1904893	regulation of JAK-STAT cascade(GO:0046425) negative regulation of JAK-STAT cascade(GO:0046426) regulation of STAT cascade(GO:1904892) negative regulation of STAT cascade(GO:1904893)
0.0	0.5	GO:0031468	nuclear envelope reassembly(GO:0031468)
0.0	0.5	GO:0001556	oocyte maturation(GO:0001556)
0.0	0.3	GO:0046606	negative regulation of centrosome cycle(GO:0046606)
0.0	0.3	GO:0030299	intestinal cholesterol absorption(GO:0030299) intestinal lipid absorption(GO:0098856)
0.0	0.0	GO:0046125	thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.0	0.2	GO:0048743	positive regulation of skeletal muscle fiber development(GO:0048743)
0.0	0.0	GO:1903377	negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.0	0.6	GO:0000188	inactivation of MAPK activity(GO:0000188)
0.0	0.1	GO:1902260	negative regulation of delayed rectifier potassium channel activity(GO:1902260) negative regulation of voltage-gated potassium channel activity(GO:1903817)
0.0	0.4	GO:0006706	steroid catabolic process(GO:0006706)
0.0	0.2	GO:0001514	selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0	0.5	GO:0007271	synaptic transmission, cholinergic(GO:0007271)
0.0	0.1	GO:0009253	peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.0	0.2	GO:0010992	ubiquitin homeostasis(GO:0010992)
0.0	0.0	GO:0070173	regulation of enamel mineralization(GO:0070173)
0.0	0.3	GO:0033141	positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0	0.0	GO:0035880	embryonic nail plate morphogenesis(GO:0035880)
0.0	0.1	GO:0006348	DNA replication-dependent nucleosome assembly(GO:0006335) chromatin silencing at telomere(GO:0006348) DNA replication-dependent nucleosome organization(GO:0034723)
0.0	0.1	GO:0009597	detection of virus(GO:0009597)
0.0	0.1	GO:0051919	positive regulation of fibrinolysis(GO:0051919)
0.0	0.4	GO:0018345	protein palmitoylation(GO:0018345)
0.0	0.1	GO:0048842	positive regulation of axon extension involved in axon guidance(GO:0048842)
0.0	0.2	GO:0002566	somatic diversification of immune receptors via somatic mutation(GO:0002566) somatic hypermutation of immunoglobulin genes(GO:0016446)
0.0	1.7	GO:0002377	immunoglobulin production(GO:0002377)
0.0	0.1	GO:0000712	resolution of meiotic recombination intermediates(GO:0000712)
0.0	0.1	GO:0014877	response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.0	0.4	GO:0090383	phagosome acidification(GO:0090383)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.6	4.7	GO:0034685	integrin alphav-beta6 complex(GO:0034685)
0.4	1.2	GO:0005607	laminin-2 complex(GO:0005607)
0.4	1.1	GO:1990032	parallel fiber(GO:1990032)
0.3	2.0	GO:0005610	laminin-5 complex(GO:0005610)
0.2	1.0	GO:0001674	female germ cell nucleus(GO:0001674)
0.2	1.2	GO:0008282	ATP-sensitive potassium channel complex(GO:0008282)
0.2	1.2	GO:0030678	mitochondrial ribonuclease P complex(GO:0030678)
0.2	0.8	GO:0034991	nuclear meiotic cohesin complex(GO:0034991)
0.2	2.4	GO:0030478	actin cap(GO:0030478)
0.2	3.5	GO:0030056	hemidesmosome(GO:0030056)
0.1	0.5	GO:1990730	VCP-NSFL1C complex(GO:1990730)
0.1	1.2	GO:0036449	microtubule minus-end(GO:0036449)
0.1	0.4	GO:0042720	mitochondrial inner membrane peptidase complex(GO:0042720)
0.1	0.9	GO:0035692	macrophage migration inhibitory factor receptor complex(GO:0035692)
0.1	0.9	GO:0071144	SMAD2-SMAD3 protein complex(GO:0071144)
0.1	0.3	GO:0070939	Dsl1p complex(GO:0070939)
0.1	0.3	GO:0036025	protein C inhibitor-TMPRSS7 complex(GO:0036024) protein C inhibitor-TMPRSS11E complex(GO:0036025) protein C inhibitor-PLAT complex(GO:0036026) protein C inhibitor-PLAU complex(GO:0036027) protein C inhibitor-thrombin complex(GO:0036028) protein C inhibitor-KLK3 complex(GO:0036029) protein C inhibitor-plasma kallikrein complex(GO:0036030) serine protease inhibitor complex(GO:0097180) protein C inhibitor-coagulation factor V complex(GO:0097181) protein C inhibitor-coagulation factor Xa complex(GO:0097182) protein C inhibitor-coagulation factor XI complex(GO:0097183)
0.1	2.2	GO:0043205	microfibril(GO:0001527) fibril(GO:0043205)
0.1	0.6	GO:0031314	extrinsic component of mitochondrial inner membrane(GO:0031314)
0.1	0.2	GO:0005873	plus-end kinesin complex(GO:0005873)
0.1	0.9	GO:0035985	senescence-associated heterochromatin focus(GO:0035985)
0.1	0.7	GO:0097169	AIM2 inflammasome complex(GO:0097169)
0.1	0.2	GO:0036195	muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.1	2.6	GO:0016010	dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1	0.6	GO:0070852	cell body fiber(GO:0070852)
0.1	2.3	GO:0030057	desmosome(GO:0030057)
0.1	1.7	GO:0005666	DNA-directed RNA polymerase III complex(GO:0005666)
0.1	0.2	GO:1990796	photoreceptor cell terminal bouton(GO:1990796)
0.1	0.8	GO:0030123	AP-3 adaptor complex(GO:0030123)
0.1	1.3	GO:0036020	endolysosome membrane(GO:0036020)
0.1	0.3	GO:0071148	TEAD-1-YAP complex(GO:0071148)
0.1	0.7	GO:1990454	L-type voltage-gated calcium channel complex(GO:1990454)
0.1	0.3	GO:0031526	brush border membrane(GO:0031526)
0.0	1.7	GO:0097228	sperm principal piece(GO:0097228)
0.0	0.1	GO:0071821	FANCM-MHF complex(GO:0071821)
0.0	0.7	GO:0043020	NADPH oxidase complex(GO:0043020)
0.0	0.6	GO:0000940	condensed chromosome outer kinetochore(GO:0000940)
0.0	4.2	GO:0001750	photoreceptor outer segment(GO:0001750)
0.0	1.2	GO:0031258	lamellipodium membrane(GO:0031258)
0.0	0.5	GO:0030008	TRAPP complex(GO:0030008)
0.0	0.1	GO:0005927	muscle tendon junction(GO:0005927)
0.0	1.7	GO:0002102	podosome(GO:0002102)
0.0	0.4	GO:0008385	IkappaB kinase complex(GO:0008385)
0.0	0.1	GO:0044305	calyx of Held(GO:0044305)
0.0	0.4	GO:0032433	filopodium tip(GO:0032433)
0.0	0.5	GO:0034663	endoplasmic reticulum chaperone complex(GO:0034663)
0.0	0.4	GO:0005869	dynactin complex(GO:0005869)
0.0	0.3	GO:0005641	nuclear envelope lumen(GO:0005641)
0.0	0.3	GO:0014701	junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0	0.5	GO:0005892	acetylcholine-gated channel complex(GO:0005892)
0.0	1.3	GO:0043198	dendritic shaft(GO:0043198)
0.0	0.8	GO:0005680	anaphase-promoting complex(GO:0005680)
0.0	0.2	GO:0030688	preribosome, small subunit precursor(GO:0030688)
0.0	0.1	GO:1990635	proximal dendrite(GO:1990635)
0.0	0.9	GO:0042571	immunoglobulin complex, circulating(GO:0042571)
0.0	0.5	GO:0005640	nuclear outer membrane(GO:0005640) platelet alpha granule membrane(GO:0031092)
0.0	0.1	GO:0042825	TAP complex(GO:0042825)
0.0	0.4	GO:0016471	vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.0	0.5	GO:0005921	gap junction(GO:0005921)
0.0	0.1	GO:0033165	interphotoreceptor matrix(GO:0033165)
0.0	0.1	GO:0061617	MICOS complex(GO:0061617)
0.0	0.9	GO:0045095	keratin filament(GO:0045095)
0.0	0.4	GO:0000314	organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0	0.4	GO:0005605	basal lamina(GO:0005605)
0.0	0.1	GO:0002193	MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0	0.8	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)
0.0	3.1	GO:0009897	external side of plasma membrane(GO:0009897)
0.0	0.2	GO:0031618	nuclear pericentric heterochromatin(GO:0031618)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.9	3.6	GO:0004666	prostaglandin-endoperoxide synthase activity(GO:0004666)
0.9	2.6	GO:0002113	interleukin-33 binding(GO:0002113)
0.4	1.2	GO:0008281	sulfonylurea receptor activity(GO:0008281)
0.2	1.2	GO:0004337	dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.2	1.9	GO:0008131	primary amine oxidase activity(GO:0008131)
0.2	0.9	GO:0010348	lithium:proton antiporter activity(GO:0010348)
0.2	0.8	GO:0046538	bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.2	1.4	GO:0070728	leucine binding(GO:0070728)
0.2	0.8	GO:0030292	protein tyrosine kinase inhibitor activity(GO:0030292)
0.2	0.9	GO:0031962	mineralocorticoid receptor binding(GO:0031962)
0.2	0.7	GO:0016936	galactoside binding(GO:0016936)
0.2	1.1	GO:0035662	Toll-like receptor 4 binding(GO:0035662)
0.1	1.1	GO:0004111	creatine kinase activity(GO:0004111)
0.1	1.0	GO:0099580	ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.1	1.9	GO:0004865	protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.1	0.4	GO:0004574	oligo-1,6-glucosidase activity(GO:0004574)
0.1	0.5	GO:0070643	vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.1	0.6	GO:0090554	phosphatidylcholine-translocating ATPase activity(GO:0090554)
0.1	0.4	GO:0008798	beta-aspartyl-peptidase activity(GO:0008798)
0.1	0.5	GO:0004657	proline dehydrogenase activity(GO:0004657)
0.1	0.8	GO:0005502	11-cis retinal binding(GO:0005502)
0.1	0.5	GO:0060961	phospholipase D inhibitor activity(GO:0060961)
0.1	1.6	GO:0005549	odorant binding(GO:0005549)
0.1	2.3	GO:0033038	bitter taste receptor activity(GO:0033038)
0.1	0.7	GO:1990254	keratin filament binding(GO:1990254)
0.1	0.4	GO:0047718	androsterone dehydrogenase activity(GO:0047023) indanol dehydrogenase activity(GO:0047718)
0.1	0.7	GO:0086056	voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.1	0.4	GO:0004802	transketolase activity(GO:0004802)
0.1	0.6	GO:0016778	diphosphotransferase activity(GO:0016778)
0.1	1.2	GO:0004526	ribonuclease P activity(GO:0004526)
0.1	2.4	GO:0005523	tropomyosin binding(GO:0005523)
0.1	0.3	GO:0008113	peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.1	2.0	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.1	0.6	GO:0000155	phosphorelay sensor kinase activity(GO:0000155)
0.1	1.3	GO:0035615	clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.1	0.9	GO:0042975	peroxisome proliferator activated receptor binding(GO:0042975)
0.1	2.0	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.1	0.3	GO:0004910	interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.1	0.6	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.1	1.1	GO:0034450	ubiquitin-ubiquitin ligase activity(GO:0034450)
0.1	0.1	GO:0046978	peptide antigen-transporting ATPase activity(GO:0015433) TAP binding(GO:0046977) TAP1 binding(GO:0046978)
0.0	0.4	GO:0060002	plus-end directed microfilament motor activity(GO:0060002)
0.0	0.1	GO:0035539	8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity(GO:0008413) 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity(GO:0035539)
0.0	0.7	GO:0016175	superoxide-generating NADPH oxidase activity(GO:0016175)
0.0	0.4	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0	4.4	GO:0001618	virus receptor activity(GO:0001618)
0.0	0.6	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0	0.3	GO:0034987	immunoglobulin receptor binding(GO:0034987)
0.0	1.1	GO:0005540	hyaluronic acid binding(GO:0005540)
0.0	0.7	GO:0050700	CARD domain binding(GO:0050700)
0.0	0.2	GO:0004800	thyroxine 5'-deiodinase activity(GO:0004800)
0.0	0.2	GO:0050544	arachidonic acid binding(GO:0050544)
0.0	0.3	GO:0016846	carbon-sulfur lyase activity(GO:0016846)
0.0	3.0	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.0	1.7	GO:0003899	DNA-directed RNA polymerase activity(GO:0003899)
0.0	0.5	GO:0015250	water channel activity(GO:0015250)
0.0	1.3	GO:0003785	actin monomer binding(GO:0003785)
0.0	0.5	GO:0031628	opioid receptor binding(GO:0031628)
0.0	6.5	GO:0003823	antigen binding(GO:0003823)
0.0	0.3	GO:0032190	acrosin binding(GO:0032190)
0.0	0.5	GO:0016500	protein-hormone receptor activity(GO:0016500)
0.0	0.2	GO:0000285	1-phosphatidylinositol-3-phosphate 5-kinase activity(GO:0000285)
0.0	0.6	GO:0004029	aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.0	0.3	GO:0043225	anion transmembrane-transporting ATPase activity(GO:0043225)
0.0	0.2	GO:0089720	caspase binding(GO:0089720)
0.0	0.4	GO:0008349	MAP kinase kinase kinase kinase activity(GO:0008349)
0.0	0.5	GO:0022848	acetylcholine-gated cation channel activity(GO:0022848)
0.0	1.1	GO:0061631	ubiquitin conjugating enzyme activity(GO:0061631)
0.0	0.2	GO:0004176	ATP-dependent peptidase activity(GO:0004176)
0.0	0.1	GO:0004815	aspartate-tRNA ligase activity(GO:0004815)
0.0	1.2	GO:0050699	WW domain binding(GO:0050699)
0.0	0.7	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
0.0	0.7	GO:0005504	fatty acid binding(GO:0005504)
0.0	1.0	GO:0005080	protein kinase C binding(GO:0005080)
0.0	0.3	GO:0005522	profilin binding(GO:0005522)
0.0	0.3	GO:0032794	GTPase activating protein binding(GO:0032794)
0.0	0.3	GO:0005132	type I interferon receptor binding(GO:0005132)
0.0	1.3	GO:0004984	olfactory receptor activity(GO:0004984)
0.0	0.0	GO:0004797	deoxycytidine kinase activity(GO:0004137) thymidine kinase activity(GO:0004797)
0.0	0.3	GO:0008179	adenylate cyclase binding(GO:0008179)
0.0	0.4	GO:0008484	sulfuric ester hydrolase activity(GO:0008484)
0.0	0.5	GO:0004435	phosphatidylinositol phospholipase C activity(GO:0004435)
0.0	0.5	GO:0004709	MAP kinase kinase kinase activity(GO:0004709)
0.0	0.3	GO:0042813	Wnt-activated receptor activity(GO:0042813)
0.0	0.3	GO:0045028	G-protein coupled nucleotide receptor activity(GO:0001608) purinergic nucleotide receptor activity(GO:0001614) nucleotide receptor activity(GO:0016502) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0	0.2	GO:0034185	apolipoprotein binding(GO:0034185)
0.0	1.4	GO:0008081	phosphoric diester hydrolase activity(GO:0008081)
0.0	0.4	GO:0019707	protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0	0.3	GO:0001134	transcription factor activity, transcription factor recruiting(GO:0001134)
0.0	0.3	GO:0008569	ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0	0.4	GO:0070840	dynein complex binding(GO:0070840)
0.0	0.6	GO:0030544	Hsp70 protein binding(GO:0030544)
0.0	0.1	GO:0071074	eukaryotic initiation factor eIF2 binding(GO:0071074)
0.0	0.3	GO:0031489	myosin V binding(GO:0031489)
0.0	0.2	GO:0016004	phospholipase activator activity(GO:0016004)
0.0	0.1	GO:0003696	satellite DNA binding(GO:0003696)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	3.6	PID_INTEGRIN4_PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.2	4.7	PID_INTEGRIN5_PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1	3.5	NABA_COLLAGENS	Genes encoding collagen proteins
0.0	2.1	PID_TNF_PATHWAY	TNF receptor signaling pathway
0.0	0.9	SA_MMP_CYTOKINE_CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0	1.3	PID_NFKAPPAB_CANONICAL_PATHWAY	Canonical NF-kappaB pathway
0.0	0.9	PID_SMAD2_3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0	0.4	PID_TCR_RAS_PATHWAY	Ras signaling in the CD4+ TCR pathway
0.0	2.4	PID_NOTCH_PATHWAY	Notch signaling pathway
0.0	0.4	PID_SYNDECAN_1_PATHWAY	Syndecan-1-mediated signaling events
0.0	0.9	ST_WNT_BETA_CATENIN_PATHWAY	Wnt/beta-catenin Pathway
0.0	1.2	PID_HEDGEHOG_GLI_PATHWAY	Hedgehog signaling events mediated by Gli proteins
0.0	0.9	PID_RAS_PATHWAY	Regulation of Ras family activation
0.0	0.7	PID_INTEGRIN2_PATHWAY	Beta2 integrin cell surface interactions
0.0	1.1	PID_KIT_PATHWAY	Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0	0.8	PID_BCR_5PATHWAY	BCR signaling pathway
0.0	0.4	PID_NEPHRIN_NEPH1_PATHWAY	Nephrin/Neph1 signaling in the kidney podocyte
0.0	0.3	ST_B_CELL_ANTIGEN_RECEPTOR	B Cell Antigen Receptor
0.0	0.8	PID_CDC42_REG_PATHWAY	Regulation of CDC42 activity
0.0	0.5	PID_ALPHA_SYNUCLEIN_PATHWAY	Alpha-synuclein signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.9	REACTOME_NOREPINEPHRINE_NEUROTRANSMITTER_RELEASE_CYCLE	Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.1	0.9	REACTOME_APOBEC3G_MEDIATED_RESISTANCE_TO_HIV1_INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.1	1.6	REACTOME_APOPTOTIC_CLEAVAGE_OF_CELL_ADHESION_PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1	1.0	REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1	1.1	REACTOME_IRAK1_RECRUITS_IKK_COMPLEX	Genes involved in IRAK1 recruits IKK complex
0.1	1.3	REACTOME_RETROGRADE_NEUROTROPHIN_SIGNALLING	Genes involved in Retrograde neurotrophin signalling
0.1	0.4	REACTOME_IRAK2_MEDIATED_ACTIVATION_OF_TAK1_COMPLEX_UPON_TLR7_8_OR_9_STIMULATION	Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0	6.9	REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS	Genes involved in Integrin cell surface interactions
0.0	0.6	REACTOME_ABACAVIR_TRANSPORT_AND_METABOLISM	Genes involved in Abacavir transport and metabolism
0.0	3.5	REACTOME_COLLAGEN_FORMATION	Genes involved in Collagen formation
0.0	0.9	REACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.0	2.2	REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0	4.2	REACTOME_PHASE1_FUNCTIONALIZATION_OF_COMPOUNDS	Genes involved in Phase 1 - Functionalization of compounds
0.0	0.4	REACTOME_DIGESTION_OF_DIETARY_CARBOHYDRATE	Genes involved in Digestion of dietary carbohydrate
0.0	0.6	REACTOME_OPSINS	Genes involved in Opsins
0.0	1.2	REACTOME_CHOLESTEROL_BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.0	2.4	REACTOME_SMOOTH_MUSCLE_CONTRACTION	Genes involved in Smooth Muscle Contraction
0.0	1.5	REACTOME_TIGHT_JUNCTION_INTERACTIONS	Genes involved in Tight junction interactions
0.0	0.5	REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS	Genes involved in Passive Transport by Aquaporins
0.0	0.7	REACTOME_INHIBITION_OF_INSULIN_SECRETION_BY_ADRENALINE_NORADRENALINE	Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0	0.4	REACTOME_SPRY_REGULATION_OF_FGF_SIGNALING	Genes involved in Spry regulation of FGF signaling
0.0	0.5	REACTOME_PRESYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS	Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0	1.0	REACTOME_PLATELET_CALCIUM_HOMEOSTASIS	Genes involved in Platelet calcium homeostasis
0.0	3.0	REACTOME_OLFACTORY_SIGNALING_PATHWAY	Genes involved in Olfactory Signaling Pathway
0.0	0.4	REACTOME_RAF_MAP_KINASE_CASCADE	Genes involved in RAF/MAP kinase cascade
0.0	1.2	REACTOME_INWARDLY_RECTIFYING_K_CHANNELS	Genes involved in Inwardly rectifying K+ channels
0.0	0.8	REACTOME_DOWNREGULATION_OF_TGF_BETA_RECEPTOR_SIGNALING	Genes involved in Downregulation of TGF-beta receptor signaling
0.0	0.4	REACTOME_THE_ACTIVATION_OF_ARYLSULFATASES	Genes involved in The activation of arylsulfatases
0.0	1.1	REACTOME_LATENT_INFECTION_OF_HOMO_SAPIENS_WITH_MYCOBACTERIUM_TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0	0.3	REACTOME_KERATAN_SULFATE_DEGRADATION	Genes involved in Keratan sulfate degradation
0.0	0.3	REACTOME_CALNEXIN_CALRETICULIN_CYCLE	Genes involved in Calnexin/calreticulin cycle
0.0	0.6	REACTOME_PHOSPHORYLATION_OF_THE_APC_C	Genes involved in Phosphorylation of the APC/C
0.0	0.4	REACTOME_IL_7_SIGNALING	Genes involved in Interleukin-7 signaling
0.0	0.5	REACTOME_METABOLISM_OF_PORPHYRINS	Genes involved in Metabolism of porphyrins
0.0	0.7	REACTOME_GLYCOSPHINGOLIPID_METABOLISM	Genes involved in Glycosphingolipid metabolism
0.0	0.5	REACTOME_ANTIGEN_PRESENTATION_FOLDING_ASSEMBLY_AND_PEPTIDE_LOADING_OF_CLASS_I_MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0	0.1	REACTOME_RNA_POL_I_PROMOTER_OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.0	0.1	REACTOME_DSCAM_INTERACTIONS	Genes involved in DSCAM interactions
0.0	0.9	REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS	Genes involved in Voltage gated Potassium channels
0.0	0.7	REACTOME_G1_PHASE	Genes involved in G1 Phase
0.0	0.5	REACTOME_AMYLOIDS	Genes involved in Amyloids
0.0	0.5	REACTOME_NETRIN1_SIGNALING	Genes involved in Netrin-1 signaling
0.0	0.2	REACTOME_PROTEOLYTIC_CLEAVAGE_OF_SNARE_COMPLEX_PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0	0.1	REACTOME_MRNA_DECAY_BY_3_TO_5_EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0	0.3	REACTOME_IL1_SIGNALING	Genes involved in Interleukin-1 signaling
0.0	0.4	REACTOME_CD28_CO_STIMULATION	Genes involved in CD28 co-stimulation
0.0	0.2	REACTOME_SYNTHESIS_OF_SUBSTRATES_IN_N_GLYCAN_BIOSYTHESIS	Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0	0.2	REACTOME_CHYLOMICRON_MEDIATED_LIPID_TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.0	2.3	REACTOME_SIGNALING_BY_RHO_GTPASES	Genes involved in Signaling by Rho GTPases

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