Motif ID: HOXB7

Z-value: 0.636


Transcription factors associated with HOXB7:

Gene SymbolEntrez IDGene Name
HOXB7 ENSG00000260027.3 HOXB7

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
HOXB7hg19_v2_chr17_-_46688334_466883850.281.8e-01Click!


Activity profile for motif HOXB7.

activity profile for motif HOXB7


Sorted Z-values histogram for motif HOXB7

Sorted Z-values for motif HOXB7



Network of associatons between targets according to the STRING database.



First level regulatory network of HOXB7

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr8_-_91095099 1.128 ENST00000265431.3
 CALB1
calbindin 1, 28kDa
chr9_+_105757590 0.892 ENST00000374798.3
ENST00000487798.1
 CYLC2

cylicin, basic protein of sperm head cytoskeleton 2

chr21_+_41029235 0.734 ENST00000380618.1
 B3GALT5
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 5
chr13_-_103719196 0.704 ENST00000245312.3
 SLC10A2
solute carrier family 10 (sodium/bile acid cotransporter), member 2
chr16_-_46655538 0.693 ENST00000303383.3
 SHCBP1
SHC SH2-domain binding protein 1
chr12_+_20968608 0.663 ENST00000553473.1
ENST00000554957.1
ENST00000381541.3
ENST00000540229.1
 SLCO1B3
SLCO1B7
LST3

solute carrier organic anion transporter family, member 1B3
solute carrier organic anion transporter family, member 1B7 (non-functional)
Putative solute carrier organic anion transporter family member 1B7; Uncharacterized protein

chr19_-_14889349 0.636 ENST00000315576.3
ENST00000392967.2
ENST00000346057.1
ENST00000353876.1
ENST00000353005.1
 EMR2




egf-like module containing, mucin-like, hormone receptor-like 2




chr12_+_21168630 0.629 ENST00000421593.2
 SLCO1B7
solute carrier organic anion transporter family, member 1B7 (non-functional)
chr1_+_152956549 0.613 ENST00000307122.2
 SPRR1A
small proline-rich protein 1A
chr2_+_234104079 0.612 ENST00000417661.1
 INPP5D
inositol polyphosphate-5-phosphatase, 145kDa
chr2_-_190044480 0.593 ENST00000374866.3
 COL5A2
collagen, type V, alpha 2
chr14_+_35591858 0.579 ENST00000603544.1
 KIAA0391
KIAA0391
chr4_+_69962212 0.576 ENST00000508661.1
 UGT2B7
UDP glucuronosyltransferase 2 family, polypeptide B7
chr4_+_69962185 0.575 ENST00000305231.7
 UGT2B7
UDP glucuronosyltransferase 2 family, polypeptide B7
chr12_+_101988774 0.564 ENST00000545503.2
ENST00000536007.1
ENST00000541119.1
ENST00000361466.2
ENST00000551300.1
ENST00000550270.1
 MYBPC1





myosin binding protein C, slow type





chr12_+_101988627 0.546 ENST00000547405.1
ENST00000452455.2
ENST00000441232.1
ENST00000360610.2
ENST00000392934.3
ENST00000547509.1
ENST00000361685.2
ENST00000549145.1
ENST00000553190.1
 MYBPC1








myosin binding protein C, slow type








chr8_-_7638935 0.538 ENST00000528972.1
 AC084121.16
proline rich 23 domain containing 2
chr12_-_28124903 0.513 ENST00000395872.1
ENST00000354417.3
ENST00000201015.4
 PTHLH


parathyroid hormone-like hormone


chr1_+_101702417 0.510 ENST00000305352.6
 S1PR1
sphingosine-1-phosphate receptor 1
chr8_+_7397150 0.485 ENST00000533250.1
 RP11-1118M6.1
proline rich 23 domain containing 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 116 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.1 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.1 1.3 GO:0052695 cellular glucuronidation(GO:0052695)
0.1 1.1 GO:0035502 metanephric part of ureteric bud development(GO:0035502)
0.1 1.1 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.0 1.1 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.9 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.1 0.8 GO:0006789 bilirubin conjugation(GO:0006789)
0.1 0.8 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.1 0.8 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.0 0.8 GO:0002076 osteoblast development(GO:0002076)
0.0 0.8 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)
0.2 0.7 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
0.1 0.7 GO:0061056 sclerotome development(GO:0061056)
0.1 0.7 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.2 0.6 GO:0045658 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.2 0.6 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.1 0.6 GO:0090646 mitochondrial tRNA processing(GO:0090646)
0.1 0.6 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.6 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.6 GO:0018149 peptide cross-linking(GO:0018149)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 46 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.1 GO:0032982 myosin filament(GO:0032982)
0.0 1.1 GO:0043195 terminal bouton(GO:0043195)
0.1 1.0 GO:0042589 zymogen granule membrane(GO:0042589)
0.3 0.9 GO:0033150 cytoskeletal calyx(GO:0033150)
0.1 0.8 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.8 GO:0001533 cornified envelope(GO:0001533)
0.2 0.6 GO:0005588 collagen type V trimer(GO:0005588)
0.1 0.6 GO:0030678 mitochondrial ribonuclease P complex(GO:0030678)
0.1 0.6 GO:0043541 UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.0 0.6 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 0.5 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.5 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.5 GO:0051233 spindle midzone(GO:0051233)
0.1 0.4 GO:0031417 NatC complex(GO:0031417)
0.1 0.4 GO:0000811 GINS complex(GO:0000811)
0.0 0.4 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.3 GO:0005587 collagen type IV trimer(GO:0005587)
0.0 0.3 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.0 0.3 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.3 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 78 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 3.3 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.1 1.3 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 1.2 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.2 1.1 GO:0005499 vitamin D binding(GO:0005499)
0.1 1.1 GO:0031432 titin binding(GO:0031432)
0.0 1.0 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.8 GO:0008329 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.1 0.7 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.1 0.7 GO:0004969 histamine receptor activity(GO:0004969)
0.1 0.7 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.7 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.0 0.7 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.7 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.7 GO:0050840 extracellular matrix binding(GO:0050840)
0.2 0.6 GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.1 0.6 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.0 0.6 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.6 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.6 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.6 GO:0005540 hyaluronic acid binding(GO:0005540)

Gene overrepresentation in C2:CP category:

Showing 1 to 8 of 8 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.3 PID_SYNDECAN_1_PATHWAY Syndecan-1-mediated signaling events
0.0 1.3 PID_GMCSF_PATHWAY GMCSF-mediated signaling events
0.0 1.2 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.0 1.2 PID_FRA_PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.5 PID_S1P_META_PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 0.5 PID_ERBB_NETWORK_PATHWAY ErbB receptor signaling network
0.0 0.5 PID_RHODOPSIN_PATHWAY Visual signal transduction: Rods
0.0 0.1 ST_INTERFERON_GAMMA_PATHWAY Interferon gamma pathway.

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 20 of 26 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 3.3 REACTOME_GLUCURONIDATION Genes involved in Glucuronidation
0.0 2.2 REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.1 1.4 REACTOME_RECYCLING_OF_BILE_ACIDS_AND_SALTS Genes involved in Recycling of bile acids and salts
0.0 1.4 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.0 1.3 REACTOME_STRIATED_MUSCLE_CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.9 REACTOME_OLFACTORY_SIGNALING_PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 0.8 REACTOME_CS_DS_DEGRADATION Genes involved in CS/DS degradation
0.0 0.6 REACTOME_INTRINSIC_PATHWAY Genes involved in Intrinsic Pathway
0.0 0.6 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.6 REACTOME_INWARDLY_RECTIFYING_K_CHANNELS Genes involved in Inwardly rectifying K+ channels
0.0 0.6 REACTOME_HS_GAG_BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.6 REACTOME_AMINE_LIGAND_BINDING_RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.6 REACTOME_IL_RECEPTOR_SHC_SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.5 REACTOME_GLUTAMATE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.5 REACTOME_REGULATION_OF_GLUCOKINASE_BY_GLUCOKINASE_REGULATORY_PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0 0.4 REACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.4 REACTOME_UNWINDING_OF_DNA Genes involved in Unwinding of DNA
0.0 0.4 REACTOME_NFKB_ACTIVATION_THROUGH_FADD_RIP1_PATHWAY_MEDIATED_BY_CASPASE_8_AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0 0.4 REACTOME_CHOLESTEROL_BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.3 REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS Genes involved in Passive Transport by Aquaporins