Motif ID: HOXB8

Z-value: 0.791


Transcription factors associated with HOXB8:

Gene SymbolEntrez IDGene Name
HOXB8 ENSG00000120068.5 HOXB8

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
HOXB8hg19_v2_chr17_-_46691990_46692066,
hg19_v2_chr17_-_46690839_46690884
0.106.5e-01Click!


Activity profile for motif HOXB8.

activity profile for motif HOXB8


Sorted Z-values histogram for motif HOXB8

Sorted Z-values for motif HOXB8



Network of associatons between targets according to the STRING database.



First level regulatory network of HOXB8

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr12_+_8975061 1.728 ENST00000299698.7
A2ML1
alpha-2-macroglobulin-like 1
chr15_-_80263506 1.620 ENST00000335661.6
BCL2A1
BCL2-related protein A1
chr4_+_75230853 1.540 ENST00000244869.2
EREG
epiregulin
chr16_-_46655538 1.529 ENST00000303383.3
SHCBP1
SHC SH2-domain binding protein 1
chr7_+_134528635 1.465 ENST00000445569.2
CALD1
caldesmon 1
chr1_-_205391178 1.296 ENST00000367153.4
ENST00000367151.2
ENST00000391936.2
ENST00000367149.3
LEMD1



LEM domain containing 1



chr20_-_1309809 1.241 ENST00000360779.3
SDCBP2
syndecan binding protein (syntenin) 2
chr3_+_100354442 1.221 ENST00000475887.1
GPR128
G protein-coupled receptor 128
chr12_-_95510743 1.179 ENST00000551521.1
FGD6
FYVE, RhoGEF and PH domain containing 6
chr1_-_200589859 1.169 ENST00000367350.4
KIF14
kinesin family member 14
chr15_-_74501360 1.138 ENST00000323940.5
STRA6
stimulated by retinoic acid 6
chr6_+_130339710 1.127 ENST00000526087.1
ENST00000533560.1
ENST00000361794.2
L3MBTL3


l(3)mbt-like 3 (Drosophila)


chr2_-_161056762 1.102 ENST00000428609.2
ENST00000409967.2
ITGB6

integrin, beta 6

chr4_+_144354644 1.088 ENST00000512843.1
GAB1
GRB2-associated binding protein 1
chr6_-_150346607 1.062 ENST00000367341.1
ENST00000286380.2
RAET1L

retinoic acid early transcript 1L

chr2_-_89630186 1.047 ENST00000390264.2
IGKV2-40
immunoglobulin kappa variable 2-40
chr6_-_131321863 1.027 ENST00000528282.1
EPB41L2
erythrocyte membrane protein band 4.1-like 2
chr7_+_134430212 0.992 ENST00000436461.2
CALD1
caldesmon 1
chr1_+_87012753 0.965 ENST00000370563.3
CLCA4
chloride channel accessory 4
chr14_+_35591858 0.959 ENST00000603544.1
KIAA0391
KIAA0391
chr9_+_33795533 0.951 ENST00000379405.3
PRSS3
protease, serine, 3
chr2_-_161056802 0.932 ENST00000283249.2
ENST00000409872.1
ITGB6

integrin, beta 6

chr10_+_17270214 0.877 ENST00000544301.1
VIM
vimentin
chr8_-_27695552 0.869 ENST00000522944.1
ENST00000301905.4
PBK

PDZ binding kinase

chr6_-_108145499 0.863 ENST00000369020.3
ENST00000369022.2
SCML4

sex comb on midleg-like 4 (Drosophila)

chr11_+_844406 0.835 ENST00000397404.1
TSPAN4
tetraspanin 4
chr9_+_128509624 0.819 ENST00000342287.5
ENST00000373487.4
PBX3

pre-B-cell leukemia homeobox 3

chr2_+_102413726 0.807 ENST00000350878.4
MAP4K4
mitogen-activated protein kinase kinase kinase kinase 4
chr10_-_90712520 0.784 ENST00000224784.6
ACTA2
actin, alpha 2, smooth muscle, aorta
chr1_+_84630645 0.775 ENST00000394839.2
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr2_+_102456277 0.760 ENST00000421882.1
MAP4K4
mitogen-activated protein kinase kinase kinase kinase 4
chr17_-_57229155 0.758 ENST00000584089.1
SKA2
spindle and kinetochore associated complex subunit 2
chr3_-_111314230 0.736 ENST00000317012.4
ZBED2
zinc finger, BED-type containing 2
chr8_-_125486755 0.734 ENST00000499418.2
ENST00000530778.1
RNF139-AS1

RNF139 antisense RNA 1 (head to head)

chr21_-_31869451 0.719 ENST00000334058.2
KRTAP19-4
keratin associated protein 19-4
chr1_+_152956549 0.704 ENST00000307122.2
SPRR1A
small proline-rich protein 1A
chr17_+_7942335 0.701 ENST00000380183.4
ENST00000572022.1
ENST00000380173.2
ALOX15B


arachidonate 15-lipoxygenase, type B


chr11_+_44117099 0.700 ENST00000533608.1
EXT2
exostosin glycosyltransferase 2
chr2_-_190044480 0.695 ENST00000374866.3
COL5A2
collagen, type V, alpha 2
chr19_+_7030589 0.690 ENST00000329753.5
MBD3L5
methyl-CpG binding domain protein 3-like 5
chr4_-_10041872 0.676 ENST00000309065.3
SLC2A9
solute carrier family 2 (facilitated glucose transporter), member 9
chr12_-_28124903 0.674 ENST00000395872.1
ENST00000354417.3
ENST00000201015.4
PTHLH


parathyroid hormone-like hormone


chr5_-_125930929 0.672 ENST00000553117.1
ENST00000447989.2
ENST00000409134.3
ALDH7A1


aldehyde dehydrogenase 7 family, member A1


chr12_-_54813229 0.671 ENST00000293379.4
ITGA5
integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr8_-_91095099 0.671 ENST00000265431.3
CALB1
calbindin 1, 28kDa
chr11_+_44117260 0.649 ENST00000358681.4
EXT2
exostosin glycosyltransferase 2
chr22_+_45148432 0.648 ENST00000389774.2
ENST00000396119.2
ENST00000336963.4
ENST00000356099.6
ENST00000412433.1
ARHGAP8




Rho GTPase activating protein 8




chr7_-_121944491 0.646 ENST00000331178.4
ENST00000427185.2
ENST00000442488.2
FEZF1


FEZ family zinc finger 1


chr1_-_63988846 0.644 ENST00000283568.8
ENST00000371092.3
ENST00000271002.10
ITGB3BP


integrin beta 3 binding protein (beta3-endonexin)


chr9_+_125133315 0.642 ENST00000223423.4
ENST00000362012.2
PTGS1

prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)

chr16_+_55512742 0.637 ENST00000568715.1
ENST00000219070.4
MMP2

matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)

chr9_+_75229616 0.637 ENST00000340019.3
TMC1
transmembrane channel-like 1
chr15_+_69706643 0.627 ENST00000352331.4
ENST00000260363.4
KIF23

kinesin family member 23

chr1_-_6420737 0.620 ENST00000541130.1
ENST00000377845.3
ACOT7

acyl-CoA thioesterase 7

chr19_+_54369608 0.614 ENST00000336967.3
MYADM
myeloid-associated differentiation marker
chr4_-_48014931 0.612 ENST00000420489.2
ENST00000504722.1
CNGA1

cyclic nucleotide gated channel alpha 1

chr8_+_31497271 0.607 ENST00000520407.1
NRG1
neuregulin 1
chr16_+_12059091 0.602 ENST00000562385.1
TNFRSF17
tumor necrosis factor receptor superfamily, member 17
chr5_-_127418573 0.599 ENST00000508353.1
ENST00000508878.1
ENST00000501652.1
ENST00000514409.1
CTC-228N24.3



CTC-228N24.3



chr4_+_169013666 0.595 ENST00000359299.3
ANXA10
annexin A10
chr19_-_42927251 0.595 ENST00000597001.1
LIPE
lipase, hormone-sensitive
chr9_-_123639304 0.587 ENST00000436309.1
PHF19
PHD finger protein 19
chr8_+_7397150 0.582 ENST00000533250.1
RP11-1118M6.1
proline rich 23 domain containing 1
chr1_+_119957554 0.572 ENST00000543831.1
ENST00000433745.1
ENST00000369416.3
HSD3B2


hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2


chr20_-_54967187 0.572 ENST00000422322.1
ENST00000371356.2
ENST00000451915.1
ENST00000347343.2
ENST00000395911.1
ENST00000395907.1
ENST00000441357.1
ENST00000456249.1
ENST00000420474.1
ENST00000395909.4
ENST00000395914.1
ENST00000312783.6
ENST00000395915.3
ENST00000395913.3
AURKA













aurora kinase A













chrX_+_38420783 0.565 ENST00000422612.2
ENST00000286824.6
ENST00000545599.1
TSPAN7


tetraspanin 7


chr8_-_7638935 0.565 ENST00000528972.1
AC084121.16
proline rich 23 domain containing 2
chr12_+_21525818 0.564 ENST00000240652.3
ENST00000542023.1
ENST00000537593.1
IAPP


islet amyloid polypeptide


chr4_+_70916119 0.555 ENST00000246896.3
ENST00000511674.1
HTN1

histatin 1

chr19_-_48753028 0.555 ENST00000522431.1
CARD8
caspase recruitment domain family, member 8
chr11_-_102496063 0.552 ENST00000260228.2
MMP20
matrix metallopeptidase 20
chr7_+_80275953 0.547 ENST00000538969.1
ENST00000544133.1
ENST00000433696.2
CD36


CD36 molecule (thrombospondin receptor)


chr21_+_41029235 0.546 ENST00000380618.1
B3GALT5
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 5
chr8_+_22422749 0.544 ENST00000523900.1
SORBS3
sorbin and SH3 domain containing 3
chr2_+_90108504 0.542 ENST00000390271.2
IGKV6D-41
immunoglobulin kappa variable 6D-41 (non-functional)
chr18_+_45778672 0.536 ENST00000600091.1
AC091150.1
HCG1818186; Uncharacterized protein
chr1_+_163291680 0.534 ENST00000450453.2
ENST00000524800.1
ENST00000442820.1
ENST00000367900.3
NUF2



NUF2, NDC80 kinetochore complex component



chr12_+_113354341 0.531 ENST00000553152.1
OAS1
2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr3_+_158787041 0.531 ENST00000471575.1
ENST00000476809.1
ENST00000485419.1
IQCJ-SCHIP1


IQCJ-SCHIP1 readthrough


chr8_-_125577940 0.531 ENST00000519168.1
ENST00000395508.2
MTSS1

metastasis suppressor 1

chr6_-_133084580 0.528 ENST00000525270.1
ENST00000530536.1
ENST00000524919.1
VNN2


vanin 2


chr3_-_145878954 0.527 ENST00000282903.5
ENST00000360060.3
PLOD2

procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2

chr12_-_28125638 0.522 ENST00000545234.1
PTHLH
parathyroid hormone-like hormone
chr8_+_36641842 0.522 ENST00000523973.1
ENST00000399881.3
KCNU1

potassium channel, subfamily U, member 1

chr1_+_24645865 0.520 ENST00000342072.4
GRHL3
grainyhead-like 3 (Drosophila)
chr15_+_67418047 0.519 ENST00000540846.2
SMAD3
SMAD family member 3
chr16_+_30064411 0.516 ENST00000338110.5
ALDOA
aldolase A, fructose-bisphosphate
chr1_+_24645807 0.514 ENST00000361548.4
GRHL3
grainyhead-like 3 (Drosophila)
chr20_-_56286479 0.514 ENST00000265626.4
PMEPA1
prostate transmembrane protein, androgen induced 1
chrX_+_38420623 0.514 ENST00000378482.2
TSPAN7
tetraspanin 7
chr11_-_28129656 0.513 ENST00000263181.6
KIF18A
kinesin family member 18A
chr1_+_152975488 0.508 ENST00000542696.1
SPRR3
small proline-rich protein 3
chr12_+_4647950 0.508 ENST00000321524.7
ENST00000543041.1
ENST00000228843.9
ENST00000352618.4
ENST00000544927.1
RAD51AP1




RAD51 associated protein 1




chr6_+_160327974 0.503 ENST00000252660.4
MAS1
MAS1 oncogene
chr12_-_22063787 0.501 ENST00000544039.1
ABCC9
ATP-binding cassette, sub-family C (CFTR/MRP), member 9
chr10_+_94352956 0.499 ENST00000260731.3
KIF11
kinesin family member 11
chr13_-_30881621 0.496 ENST00000380615.3
KATNAL1
katanin p60 subunit A-like 1
chr7_+_107224364 0.495 ENST00000491150.1
BCAP29
B-cell receptor-associated protein 29
chr17_+_61086917 0.491 ENST00000424789.2
ENST00000389520.4
TANC2

tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2

chr10_+_5238793 0.486 ENST00000263126.1
AKR1C4
aldo-keto reductase family 1, member C4
chr6_-_32157947 0.484 ENST00000375050.4
PBX2
pre-B-cell leukemia homeobox 2
chr6_-_45345597 0.482 ENST00000371460.1
ENST00000371459.1
SUPT3H

suppressor of Ty 3 homolog (S. cerevisiae)

chr2_+_17721230 0.482 ENST00000457525.1
VSNL1
visinin-like 1
chr18_+_50278430 0.479 ENST00000578080.1
ENST00000582875.1
ENST00000412726.1
DCC


deleted in colorectal carcinoma


chr6_+_167525277 0.473 ENST00000400926.2
CCR6
chemokine (C-C motif) receptor 6
chr16_+_30064444 0.473 ENST00000395248.1
ENST00000566897.1
ENST00000568435.1
ALDOA


aldolase A, fructose-bisphosphate


chr3_+_101818088 0.470 ENST00000491959.1
ZPLD1
zona pellucida-like domain containing 1
chr7_+_80275752 0.465 ENST00000419819.2
CD36
CD36 molecule (thrombospondin receptor)
chr11_-_5323226 0.463 ENST00000380224.1
OR51B4
olfactory receptor, family 51, subfamily B, member 4
chr3_+_26735991 0.461 ENST00000456208.2
LRRC3B
leucine rich repeat containing 3B
chr9_+_125132803 0.455 ENST00000540753.1
PTGS1
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr11_+_5410607 0.446 ENST00000328611.3
OR51M1
olfactory receptor, family 51, subfamily M, member 1
chr5_+_147691979 0.444 ENST00000274565.4
SPINK7
serine peptidase inhibitor, Kazal type 7 (putative)
chr11_-_66496430 0.441 ENST00000533211.1
SPTBN2
spectrin, beta, non-erythrocytic 2
chr6_+_47666275 0.439 ENST00000327753.3
ENST00000283303.2
GPR115

G protein-coupled receptor 115

chr7_+_26332645 0.438 ENST00000396376.1
SNX10
sorting nexin 10
chr18_+_22040620 0.436 ENST00000426880.2
HRH4
histamine receptor H4
chr14_+_35591928 0.433 ENST00000605870.1
ENST00000557404.3
KIAA0391

KIAA0391

chr5_+_159848854 0.426 ENST00000517480.1
ENST00000520452.1
ENST00000393964.1
PTTG1


pituitary tumor-transforming 1


chr19_+_46003056 0.426 ENST00000401593.1
ENST00000396736.2
PPM1N

protein phosphatase, Mg2+/Mn2+ dependent, 1N (putative)

chr8_-_29208183 0.421 ENST00000240100.2
DUSP4
dual specificity phosphatase 4
chr1_-_197115818 0.419 ENST00000367409.4
ENST00000294732.7
ASPM

asp (abnormal spindle) homolog, microcephaly associated (Drosophila)

chr6_+_34204642 0.419 ENST00000347617.6
ENST00000401473.3
ENST00000311487.5
ENST00000447654.1
ENST00000395004.3
HMGA1




high mobility group AT-hook 1




chrX_-_77225135 0.418 ENST00000458128.1
PGAM4
phosphoglycerate mutase family member 4
chr10_+_52152766 0.417 ENST00000596442.1
AC069547.2
Uncharacterized protein
chr12_+_56915776 0.415 ENST00000550726.1
ENST00000542360.1
RBMS2

RNA binding motif, single stranded interacting protein 2

chr14_+_22580233 0.414 ENST00000390454.2
TRAV25
T cell receptor alpha variable 25
chr2_+_234600253 0.410 ENST00000373424.1
ENST00000441351.1
UGT1A6

UDP glucuronosyltransferase 1 family, polypeptide A6

chr10_+_5488564 0.409 ENST00000449083.1
ENST00000380359.3
NET1

neuroepithelial cell transforming 1

chr19_-_7040190 0.408 ENST00000381394.4
MBD3L4
methyl-CpG binding domain protein 3-like 4
chr17_-_67057203 0.406 ENST00000340001.4
ABCA9
ATP-binding cassette, sub-family A (ABC1), member 9
chr15_-_20193370 0.406 ENST00000558565.2
IGHV3OR15-7
immunoglobulin heavy variable 3/OR15-7 (pseudogene)
chr11_+_28129795 0.404 ENST00000406787.3
ENST00000342303.5
ENST00000403099.1
ENST00000407364.3
METTL15



methyltransferase like 15



chr16_-_88729473 0.402 ENST00000301012.3
ENST00000569177.1
MVD

mevalonate (diphospho) decarboxylase

chr11_+_62623544 0.401 ENST00000377890.2
ENST00000377891.2
ENST00000377889.2
SLC3A2


solute carrier family 3 (amino acid transporter heavy chain), member 2


chr9_-_85882145 0.399 ENST00000328788.1
FRMD3
FERM domain containing 3
chr9_-_77567743 0.396 ENST00000376854.5
C9orf40
chromosome 9 open reading frame 40
chr13_-_103719196 0.395 ENST00000245312.3
SLC10A2
solute carrier family 10 (sodium/bile acid cotransporter), member 2
chr1_+_209859510 0.388 ENST00000367028.2
ENST00000261465.1
HSD11B1

hydroxysteroid (11-beta) dehydrogenase 1

chr19_-_48753064 0.387 ENST00000520153.1
ENST00000357778.5
ENST00000520015.1
CARD8


caspase recruitment domain family, member 8


chrX_+_11311533 0.387 ENST00000380714.3
ENST00000380712.3
ENST00000348912.4
AMELX


amelogenin, X-linked


chr12_+_56324933 0.387 ENST00000549629.1
ENST00000555218.1
DGKA

diacylglycerol kinase, alpha 80kDa

chr4_+_177241094 0.384 ENST00000503362.1
SPCS3
signal peptidase complex subunit 3 homolog (S. cerevisiae)
chr1_+_24646002 0.374 ENST00000356046.2
GRHL3
grainyhead-like 3 (Drosophila)
chr15_+_82722225 0.372 ENST00000300515.8
GOLGA6L9
golgin A6 family-like 9
chr12_+_43086018 0.371 ENST00000550177.1
RP11-25I15.3
RP11-25I15.3
chr2_+_113816215 0.370 ENST00000346807.3
IL36RN
interleukin 36 receptor antagonist
chr1_+_16083154 0.370 ENST00000375771.1
FBLIM1
filamin binding LIM protein 1
chr3_-_47950745 0.369 ENST00000429422.1
MAP4
microtubule-associated protein 4
chr7_+_99195677 0.366 ENST00000431679.1
GS1-259H13.2
GS1-259H13.2
chr3_+_130650738 0.363 ENST00000504612.1
ATP2C1
ATPase, Ca++ transporting, type 2C, member 1
chr9_-_21351377 0.363 ENST00000380210.1
IFNA6
interferon, alpha 6
chr16_+_11439286 0.358 ENST00000312499.5
ENST00000576027.1
RMI2

RecQ mediated genome instability 2

chr1_+_158801095 0.357 ENST00000368141.4
MNDA
myeloid cell nuclear differentiation antigen
chr3_+_189349162 0.356 ENST00000264731.3
ENST00000382063.4
ENST00000418709.2
ENST00000320472.5
ENST00000392460.3
ENST00000440651.2
TP63





tumor protein p63





chrX_-_106243451 0.355 ENST00000355610.4
ENST00000535534.1
MORC4

MORC family CW-type zinc finger 4

chr2_+_161993465 0.354 ENST00000457476.1
TANK
TRAF family member-associated NFKB activator
chr17_-_33448468 0.351 ENST00000587405.1
ENST00000591723.1
ENST00000593039.1
RAD51D
RAD51L3-RFFL

RAD51 paralog D
Uncharacterized protein

chr19_+_39903185 0.350 ENST00000409794.3
PLEKHG2
pleckstrin homology domain containing, family G (with RhoGef domain) member 2
chr4_+_74275057 0.349 ENST00000511370.1
ALB
albumin
chr12_+_4699244 0.349 ENST00000540757.2
DYRK4
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4
chr20_-_7921090 0.347 ENST00000378789.3
HAO1
hydroxyacid oxidase (glycolate oxidase) 1
chr22_-_29107919 0.347 ENST00000434810.1
ENST00000456369.1
CHEK2

checkpoint kinase 2

chr1_+_192127578 0.345 ENST00000367460.3
RGS18
regulator of G-protein signaling 18
chr13_+_30002846 0.342 ENST00000542829.1
MTUS2
microtubule associated tumor suppressor candidate 2
chr1_-_209957882 0.342 ENST00000294811.1
C1orf74
chromosome 1 open reading frame 74
chr19_+_15838834 0.339 ENST00000305899.3
OR10H2
olfactory receptor, family 10, subfamily H, member 2
chr19_-_14889349 0.337 ENST00000315576.3
ENST00000392967.2
ENST00000346057.1
ENST00000353876.1
ENST00000353005.1
EMR2




egf-like module containing, mucin-like, hormone receptor-like 2




chr18_-_19994830 0.333 ENST00000525417.1
CTAGE1
cutaneous T-cell lymphoma-associated antigen 1
chr12_-_12674032 0.331 ENST00000298573.4
DUSP16
dual specificity phosphatase 16
chr12_+_9980113 0.329 ENST00000537723.1
KLRF1
killer cell lectin-like receptor subfamily F, member 1
chr1_+_155179012 0.329 ENST00000609421.1
MTX1
metaxin 1
chr2_+_90077680 0.328 ENST00000390270.2
IGKV3D-20
immunoglobulin kappa variable 3D-20
chr2_+_201450591 0.328 ENST00000374700.2
AOX1
aldehyde oxidase 1
chr3_+_35682913 0.324 ENST00000449196.1
ARPP21
cAMP-regulated phosphoprotein, 21kDa
chr11_-_67981046 0.322 ENST00000402789.1
ENST00000402185.2
ENST00000458496.1
SUV420H1


suppressor of variegation 4-20 homolog 1 (Drosophila)


chr15_-_22448819 0.319 ENST00000604066.1
IGHV1OR15-1
immunoglobulin heavy variable 1/OR15-1 (non-functional)
chr11_+_62623621 0.319 ENST00000535296.1
SLC3A2
solute carrier family 3 (amino acid transporter heavy chain), member 2
chr14_+_22337014 0.317 ENST00000390436.2
TRAV13-1
T cell receptor alpha variable 13-1
chrX_-_19988382 0.317 ENST00000356980.3
ENST00000379687.3
ENST00000379682.4
CXorf23


chromosome X open reading frame 23


chr15_+_83098710 0.316 ENST00000561062.1
ENST00000358583.3
GOLGA6L9

golgin A6 family-like 20

chr3_+_189507523 0.316 ENST00000437221.1
ENST00000392463.2
ENST00000392461.3
ENST00000449992.1
ENST00000456148.1
TP63




tumor protein p63




chr19_+_20959098 0.315 ENST00000360204.5
ENST00000594534.1
ZNF66

zinc finger protein 66

chr18_+_29171689 0.313 ENST00000237014.3
TTR
transthyretin
chr1_+_214776516 0.313 ENST00000366955.3
CENPF
centromere protein F, 350/400kDa
chr15_+_84904525 0.312 ENST00000510439.2
GOLGA6L4
golgin A6 family-like 4
chr9_-_47314222 0.311 ENST00000420228.1
ENST00000438517.1
ENST00000414020.1
AL953854.2


AL953854.2


chr5_-_111754948 0.311 ENST00000261486.5
EPB41L4A
erythrocyte membrane protein band 4.1 like 4A
chr10_+_81967456 0.310 ENST00000422847.1
LINC00857
long intergenic non-protein coding RNA 857
chr13_-_99667960 0.310 ENST00000448493.2
DOCK9
dedicator of cytokinesis 9
chr21_+_34775181 0.309 ENST00000290219.6
IFNGR2
interferon gamma receptor 2 (interferon gamma transducer 1)
chr6_+_45390222 0.309 ENST00000359524.5
RUNX2
runt-related transcription factor 2
chr5_+_54455946 0.308 ENST00000503787.1
ENST00000296734.6
ENST00000515370.1
GPX8


glutathione peroxidase 8 (putative)


chr1_-_241803679 0.307 ENST00000331838.5
OPN3
opsin 3
chr11_+_122733011 0.307 ENST00000533709.1
CRTAM
cytotoxic and regulatory T cell molecule
chr10_+_5135981 0.305 ENST00000380554.3
AKR1C3
aldo-keto reductase family 1, member C3
chr2_+_128403439 0.304 ENST00000544369.1
GPR17
G protein-coupled receptor 17
chr11_-_33183048 0.303 ENST00000438862.2
CSTF3
cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa
chr3_-_57233966 0.301 ENST00000473921.1
ENST00000295934.3
HESX1

HESX homeobox 1

chr1_+_224544552 0.301 ENST00000465271.1
ENST00000366858.3
CNIH4

cornichon family AMPA receptor auxiliary protein 4


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0042700 luteinizing hormone signaling pathway(GO:0042700)
0.3 1.0 GO:0019285 glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456)
0.3 1.4 GO:0061143 alveolar primary septum development(GO:0061143)
0.3 0.8 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.2 1.2 GO:0032487 regulation of Rap protein signal transduction(GO:0032487)
0.2 0.7 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.2 0.6 GO:0007057 spindle assembly involved in female meiosis I(GO:0007057) positive regulation of oocyte maturation(GO:1900195)
0.2 2.1 GO:0038044 transforming growth factor-beta secretion(GO:0038044)
0.2 1.7 GO:0090646 mitochondrial tRNA processing(GO:0090646)
0.2 0.6 GO:0070173 regulation of enamel mineralization(GO:0070173)
0.2 0.9 GO:1902093 positive regulation of sperm motility(GO:1902093)
0.2 0.5 GO:0021965 spinal cord ventral commissure morphogenesis(GO:0021965)
0.2 0.6 GO:0044837 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.2 1.9 GO:0034196 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.2 0.6 GO:1900533 medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
0.2 1.1 GO:0009753 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.2 0.6 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.1 1.5 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.1 0.7 GO:0060356 leucine import(GO:0060356)
0.1 0.4 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.1 0.4 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.1 0.8 GO:0090131 mesenchyme migration(GO:0090131)
0.1 0.6 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.1 0.8 GO:0007386 compartment pattern specification(GO:0007386)
0.1 0.3 GO:0044179 hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
0.1 0.3 GO:1903926 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.1 0.8 GO:0097338 response to clozapine(GO:0097338)
0.1 0.6 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.1 0.5 GO:0030035 microspike assembly(GO:0030035)
0.1 0.6 GO:0060005 vestibular reflex(GO:0060005)
0.1 0.5 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.1 0.7 GO:0051122 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.1 0.4 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
0.1 1.2 GO:0060020 Bergmann glial cell differentiation(GO:0060020)
0.1 0.5 GO:0008065 establishment of blood-nerve barrier(GO:0008065)
0.1 0.6 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.1 0.3 GO:0019442 tryptophan catabolic process to acetyl-CoA(GO:0019442)
0.1 0.3 GO:1900158 positive regulation of osteoclast proliferation(GO:0090290) negative regulation of bone mineralization involved in bone maturation(GO:1900158)
0.1 0.3 GO:0080154 regulation of fertilization(GO:0080154)
0.1 0.5 GO:0014038 regulation of Schwann cell differentiation(GO:0014038)
0.1 0.6 GO:0021842 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.1 1.1 GO:0043249 erythrocyte maturation(GO:0043249)
0.1 0.3 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.1 0.4 GO:0090402 oncogene-induced cell senescence(GO:0090402)
0.1 0.3 GO:0046110 xanthine metabolic process(GO:0046110)
0.1 0.5 GO:0001701 in utero embryonic development(GO:0001701)
0.1 0.4 GO:0045590 negative regulation of regulatory T cell differentiation(GO:0045590)
0.1 1.5 GO:0090179 planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.1 0.6 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.1 0.7 GO:0035502 metanephric part of ureteric bud development(GO:0035502)
0.1 0.5 GO:0003383 apical constriction(GO:0003383)
0.1 0.2 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.1 0.8 GO:1901740 negative regulation of myoblast fusion(GO:1901740)
0.1 1.0 GO:1904778 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.1 0.4 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.1 0.3 GO:0045204 MAPK export from nucleus(GO:0045204)
0.1 0.2 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.1 1.1 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.1 0.4 GO:0070172 positive regulation of tooth mineralization(GO:0070172)
0.1 0.6 GO:1900004 negative regulation of serine-type endopeptidase activity(GO:1900004) negative regulation of serine-type peptidase activity(GO:1902572)
0.1 0.2 GO:0061056 sclerotome development(GO:0061056)
0.1 0.6 GO:0097646 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.1 0.2 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.1 0.4 GO:0051012 microtubule sliding(GO:0051012)
0.1 0.2 GO:0018149 peptide cross-linking(GO:0018149)
0.1 0.1 GO:1903595 positive regulation of histamine secretion by mast cell(GO:1903595)
0.1 0.4 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.1 0.8 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.1 0.3 GO:0033078 extrathymic T cell differentiation(GO:0033078)
0.1 1.6 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.1 0.4 GO:0002860 positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.1 0.9 GO:0050713 negative regulation of interleukin-1 beta secretion(GO:0050713)
0.1 1.7 GO:0002076 osteoblast development(GO:0002076)
0.1 0.5 GO:0051013 microtubule severing(GO:0051013)
0.1 1.0 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.1 0.2 GO:0032304 negative regulation of icosanoid secretion(GO:0032304)
0.1 0.5 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.1 0.2 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.1 0.3 GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.1 0.2 GO:0002384 hepatic immune response(GO:0002384)
0.1 0.4 GO:0070475 rRNA base methylation(GO:0070475)
0.1 0.2 GO:0010730 negative regulation of hydrogen peroxide biosynthetic process(GO:0010730)
0.1 0.2 GO:0002636 positive regulation of germinal center formation(GO:0002636)
0.0 0.1 GO:0003241 growth involved in heart morphogenesis(GO:0003241)
0.0 0.3 GO:1902714 negative regulation of interferon-gamma secretion(GO:1902714)
0.0 0.1 GO:0001694 histamine biosynthetic process(GO:0001694)
0.0 0.6 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.0 0.5 GO:0015939 pantothenate metabolic process(GO:0015939)
0.0 0.7 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
0.0 0.2 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.0 1.0 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)
0.0 0.2 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
0.0 0.2 GO:1904647 response to rotenone(GO:1904647)
0.0 0.3 GO:0019348 dolichol metabolic process(GO:0019348)
0.0 0.2 GO:0061763 multivesicular body-lysosome fusion(GO:0061763)
0.0 0.1 GO:0090187 positive regulation of pancreatic juice secretion(GO:0090187)
0.0 0.3 GO:0009441 glycolate metabolic process(GO:0009441)
0.0 0.2 GO:1903976 negative regulation of glial cell migration(GO:1903976)
0.0 0.1 GO:0002740 negative regulation of cytokine secretion involved in immune response(GO:0002740)
0.0 0.2 GO:0051037 regulation of transcription involved in meiotic cell cycle(GO:0051037)
0.0 0.1 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.0 0.2 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.0 1.3 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 0.1 GO:0018377 protein myristoylation(GO:0018377)
0.0 0.4 GO:0033623 regulation of integrin activation(GO:0033623)
0.0 0.8 GO:0046602 regulation of mitotic centrosome separation(GO:0046602)
0.0 1.0 GO:0006346 methylation-dependent chromatin silencing(GO:0006346)
0.0 0.7 GO:0046415 urate metabolic process(GO:0046415)
0.0 0.2 GO:2000329 negative regulation of T-helper 17 cell lineage commitment(GO:2000329)
0.0 0.2 GO:0015811 L-cystine transport(GO:0015811)
0.0 0.4 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.0 0.2 GO:0060011 Sertoli cell proliferation(GO:0060011)
0.0 0.3 GO:0070315 G1 to G0 transition involved in cell differentiation(GO:0070315)
0.0 0.1 GO:0036269 positive regulation of chronic inflammatory response(GO:0002678) swimming behavior(GO:0036269)
0.0 0.1 GO:0009138 pyrimidine nucleoside diphosphate metabolic process(GO:0009138)
0.0 0.1 GO:0051180 vitamin transport(GO:0051180)
0.0 0.2 GO:0006789 bilirubin conjugation(GO:0006789)
0.0 0.1 GO:0002188 translation reinitiation(GO:0002188)
0.0 0.2 GO:0051414 response to cortisol(GO:0051414)
0.0 0.5 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.2 GO:0051708 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.0 0.5 GO:0072520 seminiferous tubule development(GO:0072520)
0.0 0.5 GO:0038166 angiotensin-activated signaling pathway(GO:0038166)
0.0 0.3 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.0 0.3 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.0 0.2 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 0.1 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.0 0.2 GO:0010286 heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
0.0 0.2 GO:0030805 regulation of cyclic nucleotide catabolic process(GO:0030805) regulation of cAMP catabolic process(GO:0030820) regulation of purine nucleotide catabolic process(GO:0033121) regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342) negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.0 0.9 GO:0000732 strand displacement(GO:0000732)
0.0 0.2 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079)
0.0 0.2 GO:0060437 lung growth(GO:0060437)
0.0 0.1 GO:0035990 tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.0 0.7 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.0 0.2 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 1.1 GO:0035728 response to hepatocyte growth factor(GO:0035728)
0.0 0.2 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.0 0.3 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.2 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.0 0.2 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0 0.1 GO:0031548 regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
0.0 0.3 GO:0018108 peptidyl-tyrosine phosphorylation(GO:0018108)
0.0 0.1 GO:0033594 response to hydroxyisoflavone(GO:0033594) activation of phospholipase A2 activity by calcium-mediated signaling(GO:0043006)
0.0 0.1 GO:0010847 regulation of chromatin assembly(GO:0010847)
0.0 0.2 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 0.1 GO:0018874 benzoate metabolic process(GO:0018874)
0.0 0.3 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.3 GO:0030091 protein repair(GO:0030091)
0.0 0.0 GO:0033092 positive regulation of immature T cell proliferation in thymus(GO:0033092)
0.0 0.6 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0 0.4 GO:0051451 myoblast migration(GO:0051451)
0.0 0.1 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.0 0.2 GO:0051493 regulation of cytoskeleton organization(GO:0051493)
0.0 0.2 GO:0035881 amacrine cell differentiation(GO:0035881)
0.0 0.2 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.1 GO:0036229 glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803)
0.0 0.2 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.0 0.2 GO:2000049 positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
0.0 0.1 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.0 0.1 GO:0061534 gamma-aminobutyric acid secretion, neurotransmission(GO:0061534)
0.0 0.1 GO:0044854 plasma membrane raft assembly(GO:0044854) plasma membrane raft organization(GO:0044857) caveola assembly(GO:0070836)
0.0 0.9 GO:0032435 negative regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032435)
0.0 0.1 GO:0045645 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645)
0.0 0.1 GO:0060492 foregut regionalization(GO:0060423) lung field specification(GO:0060424) lung induction(GO:0060492) regulation of branching involved in lung morphogenesis(GO:0061046) positive regulation of branching involved in lung morphogenesis(GO:0061047)
0.0 0.1 GO:0019566 arabinose metabolic process(GO:0019566) L-arabinose metabolic process(GO:0046373)
0.0 0.3 GO:0030916 otic vesicle formation(GO:0030916)
0.0 1.0 GO:0016056 rhodopsin mediated signaling pathway(GO:0016056)
0.0 0.2 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 0.3 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.0 0.3 GO:0030238 male sex determination(GO:0030238)
0.0 0.3 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.3 GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.0 0.1 GO:0034334 adherens junction maintenance(GO:0034334)
0.0 0.4 GO:0030889 negative regulation of B cell proliferation(GO:0030889)
0.0 0.1 GO:0010936 negative regulation of macrophage cytokine production(GO:0010936)
0.0 0.3 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.0 0.3 GO:0021692 cerebellar Purkinje cell layer morphogenesis(GO:0021692)
0.0 0.4 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.6 GO:0006590 thyroid hormone generation(GO:0006590)
0.0 0.1 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.0 0.1 GO:0002669 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.0 0.7 GO:0034080 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0 0.1 GO:0044026 DNA hypermethylation(GO:0044026)
0.0 0.3 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.1 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.0 0.3 GO:0060087 relaxation of vascular smooth muscle(GO:0060087)
0.0 0.1 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.0 1.3 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.1 GO:0015827 tryptophan transport(GO:0015827)
0.0 1.5 GO:2000177 regulation of neural precursor cell proliferation(GO:2000177)
0.0 0.1 GO:0071874 cellular response to norepinephrine stimulus(GO:0071874)
0.0 0.3 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.1 GO:1903861 regulation of dendrite extension(GO:1903859) positive regulation of dendrite extension(GO:1903861)
0.0 0.1 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.0 0.3 GO:0060391 positive regulation of SMAD protein import into nucleus(GO:0060391)
0.0 0.4 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.0 GO:2001178 mediator complex assembly(GO:0036034) regulation of mediator complex assembly(GO:2001176) positive regulation of mediator complex assembly(GO:2001178)
0.0 0.1 GO:1990928 response to amino acid starvation(GO:1990928)
0.0 0.1 GO:0006772 thiamine metabolic process(GO:0006772)
0.0 0.8 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)
0.0 0.1 GO:0006013 mannose metabolic process(GO:0006013)
0.0 0.1 GO:0002118 aggressive behavior(GO:0002118)
0.0 0.5 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.0 0.2 GO:1900112 regulation of histone H3-K9 trimethylation(GO:1900112)
0.0 0.1 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.0 0.1 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.0 0.1 GO:0003344 pericardium morphogenesis(GO:0003344)
0.0 0.1 GO:0050893 sensory processing(GO:0050893)
0.0 0.1 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.0 0.1 GO:1903551 regulation of extracellular exosome assembly(GO:1903551)
0.0 0.1 GO:0072579 molybdenum incorporation into molybdenum-molybdopterin complex(GO:0018315) metal incorporation into metallo-molybdopterin complex(GO:0042040) glycine receptor clustering(GO:0072579)
0.0 0.5 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.1 GO:0098967 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.0 0.1 GO:0000733 DNA strand renaturation(GO:0000733)
0.0 0.5 GO:0016578 histone deubiquitination(GO:0016578)
0.0 0.2 GO:0035641 locomotory exploration behavior(GO:0035641)
0.0 0.1 GO:0048631 regulation of skeletal muscle tissue growth(GO:0048631)
0.0 0.2 GO:0007512 adult heart development(GO:0007512)
0.0 0.5 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.0 0.1 GO:0006848 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.0 0.1 GO:0051026 chiasma assembly(GO:0051026)
0.0 0.4 GO:0071539 protein localization to centrosome(GO:0071539)
0.0 0.1 GO:0006538 glutamate catabolic process(GO:0006538)
0.0 1.5 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.1 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.0 0.7 GO:2000816 negative regulation of mitotic sister chromatid separation(GO:2000816)
0.0 0.7 GO:0006379 mRNA cleavage(GO:0006379)
0.0 0.3 GO:0000338 protein deneddylation(GO:0000338)
0.0 0.1 GO:0048478 replication fork protection(GO:0048478)
0.0 0.2 GO:0010968 regulation of microtubule nucleation(GO:0010968)
0.0 0.2 GO:2000344 positive regulation of acrosome reaction(GO:2000344)
0.0 0.0 GO:0035915 pore formation in membrane of other organism(GO:0035915)
0.0 0.1 GO:0001180 transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript(GO:0001180)
0.0 0.1 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.0 0.2 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.0 1.2 GO:0046847 filopodium assembly(GO:0046847)
0.0 0.1 GO:0000432 regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432) positive regulation of transcription by glucose(GO:0046016)
0.0 0.1 GO:0009253 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.0 0.1 GO:0002322 B cell proliferation involved in immune response(GO:0002322)
0.0 0.4 GO:0009235 cobalamin metabolic process(GO:0009235)
0.0 0.3 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.0 0.2 GO:0030502 negative regulation of bone mineralization(GO:0030502)
0.0 0.1 GO:2000342 negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342)
0.0 0.1 GO:1903593 regulation of histamine secretion by mast cell(GO:1903593)
0.0 0.1 GO:0018243 protein O-linked glycosylation via threonine(GO:0018243)
0.0 0.1 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.0 0.0 GO:0046081 dUTP metabolic process(GO:0046080) dUTP catabolic process(GO:0046081)
0.0 0.2 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 0.2 GO:0009435 NAD biosynthetic process(GO:0009435)
0.0 0.2 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.0 0.1 GO:0045959 regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959)
0.0 0.1 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.0 0.2 GO:0045838 positive regulation of membrane potential(GO:0045838)
0.0 0.1 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.0 0.4 GO:0060330 regulation of response to interferon-gamma(GO:0060330) regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0 0.2 GO:1901739 regulation of myoblast fusion(GO:1901739) positive regulation of myoblast fusion(GO:1901741)
0.0 0.4 GO:0035774 positive regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0035774)
0.0 0.1 GO:0008627 intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
0.0 0.1 GO:0051418 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.0 0.2 GO:0034656 nucleobase-containing small molecule catabolic process(GO:0034656)
0.0 0.2 GO:1902358 sulfate transmembrane transport(GO:1902358)
0.0 0.0 GO:0019747 regulation of isoprenoid metabolic process(GO:0019747)
0.0 0.1 GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 0.0 GO:1904179 positive regulation of adipose tissue development(GO:1904179)
0.0 0.3 GO:0006144 purine nucleobase metabolic process(GO:0006144)
0.0 0.2 GO:1902224 ketone body metabolic process(GO:1902224)
0.0 0.5 GO:0051496 positive regulation of stress fiber assembly(GO:0051496)
0.0 0.1 GO:0001778 plasma membrane repair(GO:0001778)
0.0 0.1 GO:0042492 gamma-delta T cell differentiation(GO:0042492)
0.0 0.4 GO:0006517 protein deglycosylation(GO:0006517)
0.0 0.0 GO:1901727 positive regulation of histone deacetylase activity(GO:1901727)
0.0 0.3 GO:0045907 positive regulation of vasoconstriction(GO:0045907)
0.0 0.7 GO:0002260 lymphocyte homeostasis(GO:0002260)
0.0 0.1 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.2 GO:0007605 sensory perception of sound(GO:0007605)
0.0 0.1 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.0 0.5 GO:0010107 potassium ion import(GO:0010107)
0.0 0.3 GO:2000114 regulation of establishment of cell polarity(GO:2000114)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.1 GO:0034685 integrin alphav-beta6 complex(GO:0034685)
0.3 1.7 GO:0030678 mitochondrial ribonuclease P complex(GO:0030678)
0.2 0.7 GO:0005588 collagen type V trimer(GO:0005588)
0.2 0.8 GO:0001674 female germ cell nucleus(GO:0001674)
0.2 1.3 GO:0043541 UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.2 2.5 GO:0030478 actin cap(GO:0030478)
0.2 0.9 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.1 0.6 GO:0031417 NatC complex(GO:0031417)
0.1 0.5 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.1 0.6 GO:0097149 centralspindlin complex(GO:0097149)
0.1 0.5 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.1 0.5 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.1 1.5 GO:0008091 spectrin(GO:0008091)
0.1 0.3 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.1 1.1 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.1 0.5 GO:0031262 Ndc80 complex(GO:0031262)
0.1 1.1 GO:0072559 NLRP3 inflammasome complex(GO:0072559)
0.1 0.5 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.1 0.6 GO:0030868 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.1 0.4 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.1 0.5 GO:0036449 microtubule minus-end(GO:0036449)
0.1 0.2 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.1 1.7 GO:0051233 spindle midzone(GO:0051233)
0.1 0.3 GO:0002081 outer acrosomal membrane(GO:0002081)
0.1 0.2 GO:0036502 Derlin-1-VIMP complex(GO:0036502)
0.0 0.2 GO:0044305 calyx of Held(GO:0044305)
0.0 0.6 GO:0032426 stereocilium tip(GO:0032426)
0.0 0.4 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0 0.4 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.2 GO:0097362 MCM8-MCM9 complex(GO:0097362)
0.0 0.2 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.0 0.4 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 0.2 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.2 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 0.1 GO:0097489 multivesicular body, internal vesicle lumen(GO:0097489)
0.0 0.4 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.0 0.5 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 0.3 GO:0043196 varicosity(GO:0043196)
0.0 0.8 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.1 GO:0000811 GINS complex(GO:0000811)
0.0 0.5 GO:0000124 SAGA complex(GO:0000124)
0.0 0.1 GO:0033565 ESCRT-0 complex(GO:0033565)
0.0 0.6 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 1.0 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.1 GO:1990796 photoreceptor cell terminal bouton(GO:1990796)
0.0 0.4 GO:0033093 Weibel-Palade body(GO:0033093)
0.0 1.3 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.8 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 0.4 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.3 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.1 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.1 GO:0005873 plus-end kinesin complex(GO:0005873)
0.0 0.5 GO:0031265 CD95 death-inducing signaling complex(GO:0031265) ripoptosome(GO:0097342)
0.0 0.1 GO:0005826 actomyosin contractile ring(GO:0005826)
0.0 0.4 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 0.3 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.3 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.2 GO:0034715 pICln-Sm protein complex(GO:0034715)
0.0 0.1 GO:0031519 PcG protein complex(GO:0031519)
0.0 0.7 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.1 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0 0.1 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 0.5 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.6 GO:0030673 axolemma(GO:0030673)
0.0 0.2 GO:0061700 GATOR2 complex(GO:0061700)
0.0 1.1 GO:0031430 M band(GO:0031430)
0.0 0.1 GO:0008275 gamma-tubulin small complex(GO:0008275)
0.0 0.3 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.1 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.0 0.4 GO:0097228 sperm principal piece(GO:0097228)
0.0 0.1 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.0 0.2 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 0.2 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.0 GO:0034686 integrin alphav-beta8 complex(GO:0034686)
0.0 0.2 GO:0019774 proteasome core complex, beta-subunit complex(GO:0019774)
0.0 0.0 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.0 0.1 GO:0030936 collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
0.0 0.2 GO:0031088 platelet dense granule membrane(GO:0031088)
0.0 0.2 GO:0070419 nonhomologous end joining complex(GO:0070419)
0.0 0.1 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.1 GO:0034464 BBSome(GO:0034464)
0.0 0.0 GO:0032127 dense core granule membrane(GO:0032127)
0.0 0.1 GO:0097422 tubular endosome(GO:0097422)
0.0 0.5 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 1.2 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.6 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.1 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 1.2 GO:0005811 lipid particle(GO:0005811)
0.0 0.1 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.0 GO:0034657 GID complex(GO:0034657)
0.0 0.3 GO:0071437 invadopodium(GO:0071437)
0.0 0.1 GO:0044614 nuclear pore cytoplasmic filaments(GO:0044614)
0.0 3.0 GO:0001726 ruffle(GO:0001726)
0.0 0.1 GO:0031298 replication fork protection complex(GO:0031298)
0.0 0.2 GO:0000815 ESCRT III complex(GO:0000815)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.3 1.1 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.3 0.8 GO:0033823 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823)
0.2 0.7 GO:0016165 linoleate 13S-lipoxygenase activity(GO:0016165)
0.2 0.6 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.2 0.8 GO:0047023 androsterone dehydrogenase activity(GO:0047023)
0.2 1.6 GO:0004111 creatine kinase activity(GO:0004111)
0.2 0.6 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.2 1.0 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.2 0.5 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.1 0.4 GO:0017129 triglyceride binding(GO:0017129)
0.1 0.9 GO:0032089 NACHT domain binding(GO:0032089)
0.1 0.4 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.1 0.7 GO:0005499 vitamin D binding(GO:0005499)
0.1 0.4 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.1 0.4 GO:0046848 hydroxyapatite binding(GO:0046848)
0.1 0.9 GO:1990254 keratin filament binding(GO:1990254)
0.1 0.5 GO:0005042 netrin receptor activity(GO:0005042)
0.1 0.3 GO:0016899 oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.1 0.4 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.1 0.5 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.1 0.4 GO:0046538 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.1 0.5 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.1 1.0 GO:0042731 PH domain binding(GO:0042731)
0.1 0.3 GO:0018636 phenanthrene 9,10-monooxygenase activity(GO:0018636) ketosteroid monooxygenase activity(GO:0047086)
0.1 0.6 GO:0004447 iodide peroxidase activity(GO:0004447)
0.1 0.3 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
0.1 0.6 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.1 0.3 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.1 1.0 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.1 1.1 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.1 2.8 GO:0005523 tropomyosin binding(GO:0005523)
0.1 1.3 GO:0004526 ribonuclease P activity(GO:0004526)
0.1 0.4 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.1 0.5 GO:0001595 angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.1 0.4 GO:0004906 interferon-gamma receptor activity(GO:0004906)
0.1 0.4 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
0.1 1.6 GO:0051400 BH domain binding(GO:0051400)
0.1 0.3 GO:0051431 corticotropin-releasing hormone receptor 2 binding(GO:0051431)
0.1 0.7 GO:0004969 histamine receptor activity(GO:0004969)
0.1 0.4 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.1 0.5 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.1 0.8 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.1 1.0 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.1 0.6 GO:0035174 histone serine kinase activity(GO:0035174)
0.1 1.1 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.1 0.5 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.1 0.6 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.1 0.4 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.1 0.3 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.1 0.6 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.1 0.7 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.1 0.6 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.1 0.3 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.1 0.2 GO:0052870 tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259)
0.1 0.3 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.1 0.1 GO:0047223 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity(GO:0047223)
0.1 1.5 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.1 0.2 GO:0004531 deoxyribonuclease II activity(GO:0004531)
0.1 0.2 GO:0019981 interleukin-6 receptor activity(GO:0004915) interleukin-6 binding(GO:0019981)
0.1 1.9 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1 0.7 GO:0043855 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0 0.8 GO:0004691 cyclic nucleotide-dependent protein kinase activity(GO:0004690) cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.3 GO:0070728 leucine binding(GO:0070728)
0.0 0.6 GO:0032393 MHC class I receptor activity(GO:0032393)
0.0 0.0 GO:0017076 purine nucleotide binding(GO:0017076)
0.0 0.7 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.2 GO:0008384 IkappaB kinase activity(GO:0008384)
0.0 0.2 GO:0004802 transketolase activity(GO:0004802)
0.0 0.1 GO:0008955 peptidoglycan glycosyltransferase activity(GO:0008955)
0.0 0.3 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.0 0.6 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 0.1 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.0 0.4 GO:0043546 molybdopterin cofactor binding(GO:0043546)
0.0 0.2 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.0 0.5 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.2 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.0 0.2 GO:0035473 lipase binding(GO:0035473)
0.0 0.3 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.0 0.1 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.0 0.3 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 0.1 GO:0008431 vitamin E binding(GO:0008431)
0.0 0.2 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.0 0.1 GO:0001181 transcription factor activity, core RNA polymerase I binding(GO:0001181)
0.0 0.2 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.0 0.5 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.2 GO:0004359 glutaminase activity(GO:0004359)
0.0 0.1 GO:0004139 deoxyribose-phosphate aldolase activity(GO:0004139)
0.0 0.5 GO:0035173 histone kinase activity(GO:0035173)
0.0 0.1 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.0 0.2 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.6 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.2 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.0 0.4 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 1.7 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.8 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.5 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.0 1.7 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.2 GO:0016842 amidine-lyase activity(GO:0016842)
0.0 0.1 GO:0030760 nicotinamide N-methyltransferase activity(GO:0008112) pyridine N-methyltransferase activity(GO:0030760)
0.0 0.4 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.2 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.4 GO:0000150 recombinase activity(GO:0000150)
0.0 0.1 GO:0009041 uridylate kinase activity(GO:0009041)
0.0 0.1 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.0 0.1 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.0 0.2 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.1 GO:0005137 interleukin-5 receptor binding(GO:0005137)
0.0 0.5 GO:0017166 vinculin binding(GO:0017166)
0.0 0.3 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.1 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.0 0.1 GO:0046556 alpha-L-arabinofuranosidase activity(GO:0046556)
0.0 0.3 GO:0015924 mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.0 1.3 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.1 GO:0004974 leukotriene receptor activity(GO:0004974)
0.0 0.3 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.1 GO:0003863 alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863)
0.0 0.3 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.1 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 0.1 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.0 0.1 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.0 0.6 GO:0031489 myosin V binding(GO:0031489)
0.0 0.3 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.1 GO:0016211 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.0 0.8 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.1 GO:0015180 aromatic amino acid transmembrane transporter activity(GO:0015173) L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858)
0.0 0.7 GO:0097153 cysteine-type endopeptidase activity involved in apoptotic process(GO:0097153)
0.0 0.5 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.0 1.9 GO:0001618 virus receptor activity(GO:0001618)
0.0 0.4 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.4 GO:0043295 glutathione binding(GO:0043295)
0.0 1.2 GO:0016303 1-phosphatidylinositol-3-kinase activity(GO:0016303)
0.0 2.6 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.1 GO:0050528 acyloxyacyl hydrolase activity(GO:0050528)
0.0 0.1 GO:0030197 extracellular matrix constituent, lubricant activity(GO:0030197)
0.0 0.3 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.2 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.0 0.8 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.2 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.0 0.1 GO:0004165 dodecenoyl-CoA delta-isomerase activity(GO:0004165)
0.0 1.1 GO:0003700 nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.0 0.1 GO:0045145 single-stranded DNA 5'-3' exodeoxyribonuclease activity(GO:0045145)
0.0 0.1 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.0 0.6 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.1 GO:0004340 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0 0.2 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0 1.5 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.8 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.4 GO:0031005 filamin binding(GO:0031005)
0.0 0.1 GO:0019237 centromeric DNA binding(GO:0019237)
0.0 0.2 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.1 GO:0030348 syntaxin-3 binding(GO:0030348)
0.0 0.2 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.3 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.1 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.0 0.1 GO:0042608 T cell receptor binding(GO:0042608)
0.0 0.3 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.0 GO:0005148 prolactin receptor binding(GO:0005148)
0.0 0.1 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.0 0.3 GO:0000217 DNA secondary structure binding(GO:0000217)
0.0 1.8 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.4 GO:0001637 G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950)
0.0 0.1 GO:0036310 annealing helicase activity(GO:0036310)
0.0 0.1 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.0 GO:0004170 dUTP diphosphatase activity(GO:0004170)
0.0 0.2 GO:0048037 cofactor binding(GO:0048037)
0.0 0.7 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899)
0.0 0.2 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.0 0.3 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.2 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 1.9 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.5 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.1 GO:0050544 arachidonic acid binding(GO:0050544)
0.0 0.3 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.0 GO:0004923 leukemia inhibitory factor receptor activity(GO:0004923)
0.0 0.3 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.2 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.0 0.9 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.1 GO:0003713 transcription coactivator activity(GO:0003713)
0.0 0.1 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 2.0 GO:0003823 antigen binding(GO:0003823)
0.0 0.3 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.0 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 0.0 GO:0070568 guanylyltransferase activity(GO:0070568)
0.0 0.2 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.1 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.0 0.2 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 0.0 GO:0052590 sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
0.0 0.2 GO:0042288 MHC class I protein binding(GO:0042288)
0.0 0.1 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 0.1 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.6 PID_ERBB_NETWORK_PATHWAY ErbB receptor signaling network
0.1 2.0 PID_INTEGRIN5_PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.5 SA_G2_AND_M_PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 1.2 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.0 1.1 PID_ERBB1_RECEPTOR_PROXIMAL_PATHWAY EGF receptor (ErbB1) signaling pathway
0.0 2.1 PID_AURORA_B_PATHWAY Aurora B signaling
0.0 0.7 PID_LYMPH_ANGIOGENESIS_PATHWAY VEGFR3 signaling in lymphatic endothelium
0.0 2.1 PID_NFAT_TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 1.6 PID_FOXM1_PATHWAY FOXM1 transcription factor network
0.0 1.0 PID_GMCSF_PATHWAY GMCSF-mediated signaling events
0.0 0.8 PID_RHODOPSIN_PATHWAY Visual signal transduction: Rods
0.0 1.5 PID_EPHB_FWD_PATHWAY EPHB forward signaling
0.0 1.4 PID_BCR_5PATHWAY BCR signaling pathway
0.0 0.5 PID_SMAD2_3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.5 SA_FAS_SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.9 NABA_COLLAGENS Genes encoding collagen proteins
0.0 0.2 ST_STAT3_PATHWAY STAT3 Pathway
0.0 0.5 ST_ERK1_ERK2_MAPK_PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.5 PID_NETRIN_PATHWAY Netrin-mediated signaling events
0.0 0.3 PID_ERB_GENOMIC_PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.8 PID_CDC42_REG_PATHWAY Regulation of CDC42 activity
0.0 0.4 PID_CXCR3_PATHWAY CXCR3-mediated signaling events
0.0 0.4 PID_P38_ALPHA_BETA_PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.8 PID_RHOA_REG_PATHWAY Regulation of RhoA activity
0.0 3.2 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.1 REACTOME_SHC1_EVENTS_IN_ERBB4_SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.1 0.3 REACTOME_SHC1_EVENTS_IN_EGFR_SIGNALING Genes involved in SHC1 events in EGFR signaling
0.1 0.4 REACTOME_RECYCLING_OF_BILE_ACIDS_AND_SALTS Genes involved in Recycling of bile acids and salts
0.1 1.3 REACTOME_SIGNALING_BY_CONSTITUTIVELY_ACTIVE_EGFR Genes involved in Signaling by constitutively active EGFR
0.1 3.8 REACTOME_SMOOTH_MUSCLE_CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 2.0 REACTOME_KINESINS Genes involved in Kinesins
0.0 1.4 REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.5 REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_24_HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.6 REACTOME_ANDROGEN_BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 1.1 REACTOME_EFFECTS_OF_PIP2_HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.9 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.6 REACTOME_NRIF_SIGNALS_CELL_DEATH_FROM_THE_NUCLEUS Genes involved in NRIF signals cell death from the nucleus
0.0 0.5 REACTOME_ROLE_OF_SECOND_MESSENGERS_IN_NETRIN1_SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 1.1 REACTOME_DOWNREGULATION_OF_TGF_BETA_RECEPTOR_SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.4 REACTOME_ERKS_ARE_INACTIVATED Genes involved in ERKs are inactivated
0.0 1.3 REACTOME_HS_GAG_BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.4 REACTOME_CDC6_ASSOCIATION_WITH_THE_ORC_ORIGIN_COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 1.0 REACTOME_ANTIGEN_PROCESSING_CROSS_PRESENTATION Genes involved in Antigen processing-Cross presentation
0.0 0.6 REACTOME_ABCA_TRANSPORTERS_IN_LIPID_HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.2 REACTOME_NFKB_IS_ACTIVATED_AND_SIGNALS_SURVIVAL Genes involved in NF-kB is activated and signals survival
0.0 0.2 REACTOME_APOBEC3G_MEDIATED_RESISTANCE_TO_HIV1_INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.6 REACTOME_FACILITATIVE_NA_INDEPENDENT_GLUCOSE_TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 3.2 REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.6 REACTOME_HDL_MEDIATED_LIPID_TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 1.0 REACTOME_BASIGIN_INTERACTIONS Genes involved in Basigin interactions
0.0 0.5 REACTOME_TRYPTOPHAN_CATABOLISM Genes involved in Tryptophan catabolism
0.0 1.6 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.0 0.9 REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.6 REACTOME_AMINE_DERIVED_HORMONES Genes involved in Amine-derived hormones
0.0 0.3 REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 2.9 REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.4 REACTOME_EICOSANOID_LIGAND_BINDING_RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.0 1.0 REACTOME_GLYCOLYSIS Genes involved in Glycolysis
0.0 0.3 REACTOME_OPSINS Genes involved in Opsins
0.0 0.3 REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.2 REACTOME_GLYCOPROTEIN_HORMONES Genes involved in Glycoprotein hormones
0.0 0.8 REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.5 REACTOME_PROCESSING_OF_INTRONLESS_PRE_MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.5 REACTOME_EXTRINSIC_PATHWAY_FOR_APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.5 REACTOME_ABC_FAMILY_PROTEINS_MEDIATED_TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.6 REACTOME_BETA_DEFENSINS Genes involved in Beta defensins
0.0 0.4 REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.6 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.3 REACTOME_G2_M_DNA_DAMAGE_CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.3 REACTOME_SYNTHESIS_OF_SUBSTRATES_IN_N_GLYCAN_BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.1 REACTOME_SPRY_REGULATION_OF_FGF_SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.4 REACTOME_REGULATION_OF_IFNG_SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.8 REACTOME_AMINE_LIGAND_BINDING_RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.1 REACTOME_BINDING_AND_ENTRY_OF_HIV_VIRION Genes involved in Binding and entry of HIV virion
0.0 0.3 REACTOME_THE_ACTIVATION_OF_ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.3 REACTOME_RAP1_SIGNALLING Genes involved in Rap1 signalling
0.0 0.3 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_EARLY_ENDOSOME_MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.2 REACTOME_IL_6_SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.4 REACTOME_CTLA4_INHIBITORY_SIGNALING Genes involved in CTLA4 inhibitory signaling
0.0 0.4 REACTOME_ENDOSOMAL_SORTING_COMPLEX_REQUIRED_FOR_TRANSPORT_ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.4 REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.4 REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.2 REACTOME_SLBP_DEPENDENT_PROCESSING_OF_REPLICATION_DEPENDENT_HISTONE_PRE_MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 0.5 REACTOME_OXYGEN_DEPENDENT_PROLINE_HYDROXYLATION_OF_HYPOXIA_INDUCIBLE_FACTOR_ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.4 REACTOME_CHOLESTEROL_BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.2 REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.3 REACTOME_PLATELET_CALCIUM_HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.8 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK
0.0 0.7 REACTOME_INTERFERON_ALPHA_BETA_SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.2 REACTOME_CYCLIN_A_B1_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 1.0 REACTOME_OLFACTORY_SIGNALING_PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 1.1 REACTOME_MITOTIC_PROMETAPHASE Genes involved in Mitotic Prometaphase