Motif ID: HOXC13

Z-value: 0.747


Transcription factors associated with HOXC13:

Gene SymbolEntrez IDGene Name
HOXC13 ENSG00000123364.3 HOXC13

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
HOXC13hg19_v2_chr12_+_54332535_54332636-0.537.2e-03Click!


Activity profile for motif HOXC13.

activity profile for motif HOXC13


Sorted Z-values histogram for motif HOXC13

Sorted Z-values for motif HOXC13



Network of associatons between targets according to the STRING database.



First level regulatory network of HOXC13

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_+_88117683 1.846 ENST00000369562.4
 C6ORF165
UPF0704 protein C6orf165
chr1_-_47407097 1.791 ENST00000457840.2
 CYP4A11
cytochrome P450, family 4, subfamily A, polypeptide 11
chr1_-_109656439 1.388 ENST00000369949.4
 C1orf194
chromosome 1 open reading frame 194
chr15_+_71228826 1.322 ENST00000558456.1
ENST00000560158.2
ENST00000558808.1
ENST00000559806.1
ENST00000559069.1
 LRRC49




leucine rich repeat containing 49




chr10_+_51549498 1.064 ENST00000358559.2
ENST00000298239.6
 MSMB

microseminoprotein, beta-

chr13_-_20077417 1.054 ENST00000382978.1
ENST00000400230.2
ENST00000255310.6
 TPTE2


transmembrane phosphoinositide 3-phosphatase and tensin homolog 2


chr15_+_71184931 0.920 ENST00000560369.1
ENST00000260382.5
 LRRC49

leucine rich repeat containing 49

chr15_+_71185148 0.899 ENST00000443425.2
ENST00000560755.1
 LRRC49

leucine rich repeat containing 49

chr4_-_147866960 0.855 ENST00000513335.1
 TTC29
tetratricopeptide repeat domain 29
chr4_+_70861647 0.840 ENST00000246895.4
ENST00000381060.2
 STATH

statherin

chr17_-_39165366 0.811 ENST00000391588.1
 KRTAP3-1
keratin associated protein 3-1
chr1_+_246887349 0.715 ENST00000366510.3
 SCCPDH
saccharopine dehydrogenase (putative)
chr19_+_38085731 0.708 ENST00000589117.1
 ZNF540
zinc finger protein 540
chr4_-_150736962 0.694 ENST00000502345.1
ENST00000510975.1
ENST00000511993.1
 RP11-526A4.1


RP11-526A4.1


chr4_-_148605265 0.665 ENST00000541232.1
ENST00000322396.6
 PRMT10

protein arginine methyltransferase 10 (putative)

chr7_-_69062391 0.655 ENST00000436600.2
 RP5-942I16.1
RP5-942I16.1
chr7_+_138915102 0.651 ENST00000486663.1
 UBN2
ubinuclein 2
chr4_+_95679072 0.647 ENST00000515059.1
 BMPR1B
bone morphogenetic protein receptor, type IB
chr6_+_127898312 0.641 ENST00000329722.7
 C6orf58
chromosome 6 open reading frame 58
chr1_-_149832704 0.622 ENST00000392933.1
ENST00000369157.2
ENST00000392932.4
 HIST2H4B


histone cluster 2, H4b



Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 54 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 1.8 GO:0003095 pressure natriuresis(GO:0003095)
0.1 0.8 GO:0046541 saliva secretion(GO:0046541)
0.0 0.7 GO:0035082 axoneme assembly(GO:0035082)
0.1 0.6 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.1 0.6 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.0 0.6 GO:0050974 detection of mechanical stimulus involved in sensory perception(GO:0050974)
0.1 0.5 GO:0060830 intraciliary anterograde transport(GO:0035720) ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
0.1 0.5 GO:0001970 positive regulation of activation of membrane attack complex(GO:0001970)
0.1 0.5 GO:0060741 prostate gland stromal morphogenesis(GO:0060741) seminal vesicle development(GO:0061107)
0.1 0.5 GO:0002669 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.1 0.5 GO:2000334 lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096) blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.0 0.5 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.5 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.0 0.5 GO:0045026 plasma membrane fusion(GO:0045026)
0.1 0.4 GO:1904209 regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
0.1 0.4 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.0 0.4 GO:0060312 regulation of blood vessel remodeling(GO:0060312)
0.0 0.4 GO:1902951 negative regulation of dendritic spine maintenance(GO:1902951)
0.0 0.4 GO:0001973 adenosine receptor signaling pathway(GO:0001973)
0.0 0.4 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 23 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.9 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.6 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.1 0.5 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.5 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.5 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 0.5 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.5 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.4 GO:0033269 internode region of axon(GO:0033269)
0.1 0.3 GO:0030849 autosome(GO:0030849)
0.0 0.3 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.3 GO:0032982 myosin filament(GO:0032982)
0.1 0.2 GO:0097233 lamellar body membrane(GO:0097232) alveolar lamellar body membrane(GO:0097233)
0.0 0.2 GO:0070761 pre-snoRNP complex(GO:0070761)
0.0 0.1 GO:0044609 DBIRD complex(GO:0044609)
0.0 0.1 GO:0036398 TCR signalosome(GO:0036398)
0.0 0.1 GO:0097444 spine apparatus(GO:0097444)
0.0 0.1 GO:0032301 MutSalpha complex(GO:0032301)
0.0 0.1 GO:1902560 GMP reductase complex(GO:1902560)
0.0 0.1 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 0.1 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 32 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 1.8 GO:0018685 alkane 1-monooxygenase activity(GO:0018685)
0.3 1.1 GO:0051800 phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity(GO:0051800)
0.1 0.9 GO:0042608 T cell receptor binding(GO:0042608)
0.1 0.9 GO:0032395 MHC class II receptor activity(GO:0032395)
0.0 0.9 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.3 0.8 GO:0046848 hydroxyapatite binding(GO:0046848)
0.1 0.6 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.1 0.6 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.6 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.6 GO:0070330 aromatase activity(GO:0070330)
0.1 0.5 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.0 0.5 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 0.4 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.0 0.4 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.4 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.4 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.4 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.4 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.4 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.0 0.4 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)

Gene overrepresentation in C2:CP category:

Showing 1 to 4 of 4 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.7 PID_IL12_STAT4_PATHWAY IL12 signaling mediated by STAT4
0.0 0.6 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.4 PID_VEGF_VEGFR_PATHWAY VEGF and VEGFR signaling network
0.0 0.4 PID_SYNDECAN_3_PATHWAY Syndecan-3-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 12 of 12 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.9 REACTOME_CYTOCHROME_P450_ARRANGED_BY_SUBSTRATE_TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 1.1 REACTOME_TRANSLOCATION_OF_ZAP_70_TO_IMMUNOLOGICAL_SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 1.1 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_GOLGI_MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 1.1 REACTOME_PACKAGING_OF_TELOMERE_ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.7 REACTOME_CHONDROITIN_SULFATE_BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.6 REACTOME_SIGNALING_BY_BMP Genes involved in Signaling by BMP
0.0 0.4 REACTOME_PLATELET_ADHESION_TO_EXPOSED_COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.4 REACTOME_VEGF_LIGAND_RECEPTOR_INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.4 REACTOME_NUCLEOTIDE_LIKE_PURINERGIC_RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.0 0.3 REACTOME_NFKB_ACTIVATION_THROUGH_FADD_RIP1_PATHWAY_MEDIATED_BY_CASPASE_8_AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0 0.3 REACTOME_ZINC_TRANSPORTERS Genes involved in Zinc transporters
0.0 0.1 REACTOME_GPVI_MEDIATED_ACTIVATION_CASCADE Genes involved in GPVI-mediated activation cascade