Motif ID: HOXD1

Z-value: 0.479


Transcription factors associated with HOXD1:

Gene SymbolEntrez IDGene Name
HOXD1 ENSG00000128645.11 HOXD1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
HOXD1hg19_v2_chr2_+_177053307_177053402-0.395.7e-02Click!


Activity profile for motif HOXD1.

activity profile for motif HOXD1


Sorted Z-values histogram for motif HOXD1

Sorted Z-values for motif HOXD1



Network of associatons between targets according to the STRING database.



First level regulatory network of HOXD1

PNG image of the network

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Top targets:


Showing 1 to 20 of 72 entries
PromoterScoreRefseqGene SymbolGene Name
chr11_+_101918153 2.452 ENST00000434758.2
ENST00000526781.1
ENST00000534360.1
C11orf70


chromosome 11 open reading frame 70


chr13_+_36050881 2.018 ENST00000537702.1
NBEA
neurobeachin
chr2_+_228736335 1.711 ENST00000440997.1
ENST00000545118.1
DAW1

dynein assembly factor with WDR repeat domains 1

chr11_+_71900703 1.353 ENST00000393681.2
FOLR1
folate receptor 1 (adult)
chr11_+_71900572 1.319 ENST00000312293.4
FOLR1
folate receptor 1 (adult)
chr11_-_26593779 1.142 ENST00000529533.1
MUC15
mucin 15, cell surface associated
chr4_-_25865159 0.818 ENST00000502949.1
ENST00000264868.5
ENST00000513691.1
ENST00000514872.1
SEL1L3



sel-1 suppressor of lin-12-like 3 (C. elegans)



chr11_-_26593649 0.808 ENST00000455601.2
MUC15
mucin 15, cell surface associated
chr5_-_96478466 0.806 ENST00000274382.4
LIX1
Lix1 homolog (chicken)
chr7_+_133812052 0.727 ENST00000285928.2
LRGUK
leucine-rich repeats and guanylate kinase domain containing
chr11_-_26593677 0.686 ENST00000527569.1
MUC15
mucin 15, cell surface associated
chr14_+_74034310 0.649 ENST00000538782.1
ACOT2
acyl-CoA thioesterase 2
chr20_-_50418972 0.562 ENST00000395997.3
SALL4
spalt-like transcription factor 4
chr9_-_5339873 0.541 ENST00000223862.1
ENST00000223858.4
RLN1

relaxin 1

chrX_+_77154935 0.531 ENST00000481445.1
COX7B
cytochrome c oxidase subunit VIIb
chr20_-_50418947 0.527 ENST00000371539.3
SALL4
spalt-like transcription factor 4
chr20_-_50419055 0.512 ENST00000217086.4
SALL4
spalt-like transcription factor 4
chr20_+_43990576 0.482 ENST00000372727.1
ENST00000414310.1
SYS1

SYS1 Golgi-localized integral membrane protein homolog (S. cerevisiae)

chr7_+_99717230 0.473 ENST00000262932.3
CNPY4
canopy FGF signaling regulator 4
chrX_+_77166172 0.470 ENST00000343533.5
ENST00000350425.4
ENST00000341514.6
ATP7A


ATPase, Cu++ transporting, alpha polypeptide



Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 20 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.9 2.7 GO:0003147 neural crest cell migration involved in heart formation(GO:0003147) anterior neural tube closure(GO:0061713)
0.0 2.6 GO:0016266 O-glycan processing(GO:0016266)
0.0 1.7 GO:0007368 determination of left/right symmetry(GO:0007368)
0.1 1.6 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 0.8 GO:0097352 autophagosome maturation(GO:0097352)
0.0 0.7 GO:0035082 axoneme assembly(GO:0035082)
0.0 0.6 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)
0.2 0.5 GO:0071284 cellular response to lead ion(GO:0071284)
0.0 0.5 GO:0051382 kinetochore assembly(GO:0051382)
0.0 0.5 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.5 GO:0006895 Golgi to endosome transport(GO:0006895)
0.1 0.4 GO:2001295 malonyl-CoA biosynthetic process(GO:2001295)
0.0 0.4 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.0 0.2 GO:0030242 pexophagy(GO:0030242)
0.0 0.2 GO:0010025 wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.0 0.2 GO:0002414 immunoglobulin transcytosis in epithelial cells(GO:0002414)
0.0 0.2 GO:0042670 photoreceptor cell outer segment organization(GO:0035845) retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0 0.1 GO:0035553 oxidative RNA demethylation(GO:0035513) oxidative single-stranded RNA demethylation(GO:0035553)
0.0 0.1 GO:2000645 negative regulation of receptor catabolic process(GO:2000645)
0.0 0.1 GO:0030327 prenylated protein catabolic process(GO:0030327)

Gene overrepresentation in cellular_component category:

Showing 1 to 6 of 6 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.7 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 2.6 GO:0005796 Golgi lumen(GO:0005796)
0.0 1.6 GO:0000792 heterochromatin(GO:0000792)
0.1 0.7 GO:0002177 manchette(GO:0002177)
0.0 0.5 GO:0045277 respiratory chain complex IV(GO:0045277)
0.0 0.5 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)

Gene overrepresentation in molecular_function category:

Showing 1 to 11 of 11 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.7 2.7 GO:0061714 folic acid receptor activity(GO:0061714)
0.0 0.6 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.2 0.5 GO:0032767 copper-dependent protein binding(GO:0032767)
0.0 0.5 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 0.4 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.1 0.2 GO:0019770 IgG receptor activity(GO:0019770)
0.0 0.2 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.0 0.2 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.2 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.1 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
0.0 0.1 GO:0003998 acylphosphatase activity(GO:0003998)

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 3 of 3 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.6 REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.4 REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.4 REACTOME_ACTIVATED_AMPK_STIMULATES_FATTY_ACID_OXIDATION_IN_MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle