Motif ID: HOXD11_HOXA11

Z-value: 0.788

Transcription factors associated with HOXD11_HOXA11:

Gene SymbolEntrez IDGene Name
HOXA11 ENSG00000005073.5 HOXA11
HOXD11 ENSG00000128713.11 HOXD11

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
HOXD11hg19_v2_chr2_+_176972000_1769720250.154.7e-01Click!
HOXA11hg19_v2_chr7_-_27224795_27224840,
hg19_v2_chr7_-_27224842_27224872
-0.038.7e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of HOXD11_HOXA11

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_-_216300784 1.714 ENST00000421182.1
ENST00000432072.2
ENST00000323926.6
ENST00000336916.4
ENST00000357867.4
ENST00000359671.1
ENST00000346544.3
ENST00000345488.5
ENST00000357009.2
ENST00000446046.1
ENST00000356005.4
ENST00000443816.1
ENST00000426059.1
ENST00000354785.4
FN1













fibronectin 1













chr21_-_31869451 1.486 ENST00000334058.2
KRTAP19-4
keratin associated protein 19-4
chr10_+_118187379 1.405 ENST00000369230.3
PNLIPRP3
pancreatic lipase-related protein 3
chr20_+_30102231 1.346 ENST00000335574.5
ENST00000340852.5
ENST00000398174.3
ENST00000376127.3
ENST00000344042.5
HM13




histocompatibility (minor) 13




chr4_+_169013666 1.162 ENST00000359299.3
ANXA10
annexin A10
chr1_+_62439037 1.136 ENST00000545929.1
INADL
InaD-like (Drosophila)
chr4_-_68749699 1.120 ENST00000545541.1
TMPRSS11D
transmembrane protease, serine 11D
chr11_+_76745385 1.099 ENST00000533140.1
ENST00000354301.5
ENST00000528622.1
B3GNT6


UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6 (core 3 synthase)


chr6_+_12290586 1.089 ENST00000379375.5
EDN1
endothelin 1
chr2_+_158114051 1.066 ENST00000259056.4
GALNT5
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5 (GalNAc-T5)
chr5_-_39270725 1.050 ENST00000512138.1
ENST00000512982.1
ENST00000540520.1
FYB


FYN binding protein


chr4_-_68749745 0.926 ENST00000283916.6
TMPRSS11D
transmembrane protease, serine 11D
chr9_-_21305312 0.879 ENST00000259555.4
IFNA5
interferon, alpha 5
chr5_+_7654057 0.873 ENST00000537121.1
ADCY2
adenylate cyclase 2 (brain)
chr7_-_41742697 0.867 ENST00000242208.4
INHBA
inhibin, beta A
chr7_+_134464376 0.811 ENST00000454108.1
ENST00000361675.2
CALD1

caldesmon 1

chrX_-_73072534 0.808 ENST00000429829.1
XIST
X inactive specific transcript (non-protein coding)
chr21_-_31859755 0.802 ENST00000334055.3
KRTAP19-2
keratin associated protein 19-2
chr12_-_25055177 0.787 ENST00000538118.1
BCAT1
branched chain amino-acid transaminase 1, cytosolic
chr4_+_86525299 0.783 ENST00000512201.1
ARHGAP24
Rho GTPase activating protein 24
chr7_+_134464414 0.770 ENST00000361901.2
CALD1
caldesmon 1
chr8_-_125486755 0.737 ENST00000499418.2
ENST00000530778.1
RNF139-AS1

RNF139 antisense RNA 1 (head to head)

chr13_-_103719196 0.730 ENST00000245312.3
SLC10A2
solute carrier family 10 (sodium/bile acid cotransporter), member 2
chr9_+_105757590 0.727 ENST00000374798.3
ENST00000487798.1
CYLC2

cylicin, basic protein of sperm head cytoskeleton 2

chr17_+_7211656 0.694 ENST00000416016.2
EIF5A
eukaryotic translation initiation factor 5A
chr10_+_102222798 0.687 ENST00000343737.5
WNT8B
wingless-type MMTV integration site family, member 8B
chr12_-_95510743 0.678 ENST00000551521.1
FGD6
FYVE, RhoGEF and PH domain containing 6
chr14_-_51027838 0.618 ENST00000555216.1
MAP4K5
mitogen-activated protein kinase kinase kinase kinase 5
chr18_-_12656715 0.615 ENST00000462226.1
ENST00000497844.2
ENST00000309836.5
ENST00000453447.2
SPIRE1



spire-type actin nucleation factor 1



chr19_-_10420459 0.609 ENST00000403352.1
ENST00000403903.3
ZGLP1

zinc finger, GATA-like protein 1

chr2_-_31440377 0.572 ENST00000444918.2
ENST00000403897.3
CAPN14

calpain 14

chr18_-_5396271 0.565 ENST00000579951.1
EPB41L3
erythrocyte membrane protein band 4.1-like 3
chr7_+_80275953 0.565 ENST00000538969.1
ENST00000544133.1
ENST00000433696.2
CD36


CD36 molecule (thrombospondin receptor)


chr12_+_130646999 0.564 ENST00000539839.1
ENST00000229030.4
FZD10

frizzled family receptor 10

chr2_+_31456874 0.555 ENST00000541626.1
EHD3
EH-domain containing 3
chr3_+_140981456 0.554 ENST00000504264.1
ACPL2
acid phosphatase-like 2
chr7_+_138915102 0.550 ENST00000486663.1
UBN2
ubinuclein 2
chr7_+_79998864 0.547 ENST00000435819.1
CD36
CD36 molecule (thrombospondin receptor)
chr14_-_57272366 0.536 ENST00000554788.1
ENST00000554845.1
ENST00000408990.3
OTX2


orthodenticle homeobox 2


chr20_+_37554955 0.535 ENST00000217429.4
FAM83D
family with sequence similarity 83, member D
chr3_+_100328433 0.521 ENST00000273352.3
GPR128
G protein-coupled receptor 128
chr7_+_141811539 0.518 ENST00000550469.2
ENST00000477922.3
RP11-1220K2.2

Putative inactive maltase-glucoamylase-like protein LOC93432

chr2_+_89986318 0.517 ENST00000491977.1
IGKV2D-29
immunoglobulin kappa variable 2D-29
chr7_+_40174565 0.498 ENST00000309930.5
ENST00000401647.2
ENST00000335693.4
ENST00000413931.1
ENST00000416370.1
ENST00000540834.1
C7orf10





succinylCoA:glutarate-CoA transferase





chr8_-_91095099 0.492 ENST00000265431.3
CALB1
calbindin 1, 28kDa
chr8_+_118147498 0.488 ENST00000519688.1
ENST00000456015.2
SLC30A8

solute carrier family 30 (zinc transporter), member 8

chr12_-_52779433 0.485 ENST00000257951.3
KRT84
keratin 84
chr19_-_19626351 0.484 ENST00000585580.3
TSSK6
testis-specific serine kinase 6
chr9_+_12693336 0.483 ENST00000381137.2
ENST00000388918.5
TYRP1

tyrosinase-related protein 1

chr10_-_96829246 0.482 ENST00000371270.3
ENST00000535898.1
ENST00000539050.1
CYP2C8


cytochrome P450, family 2, subfamily C, polypeptide 8


chr8_+_52730143 0.481 ENST00000415643.1
AC090186.1
Uncharacterized protein
chr1_+_153004800 0.480 ENST00000392661.3
SPRR1B
small proline-rich protein 1B
chr10_-_103599591 0.478 ENST00000348850.5
KCNIP2
Kv channel interacting protein 2
chr17_-_39646116 0.477 ENST00000328119.6
KRT36
keratin 36
chr7_+_26591441 0.465 ENST00000420912.1
ENST00000457000.1
ENST00000430426.1
AC004947.2


AC004947.2


chr3_+_16306837 0.465 ENST00000606098.1
OXNAD1
oxidoreductase NAD-binding domain containing 1
chr1_+_84630645 0.459 ENST00000394839.2
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr4_-_100065419 0.456 ENST00000504125.1
ENST00000505590.1
ADH4

alcohol dehydrogenase 4 (class II), pi polypeptide

chr2_-_190044480 0.448 ENST00000374866.3
COL5A2
collagen, type V, alpha 2
chr19_-_53636125 0.441 ENST00000601493.1
ENST00000599261.1
ENST00000597503.1
ENST00000500065.4
ENST00000243643.4
ENST00000594011.1
ENST00000455735.2
ENST00000595193.1
ENST00000448501.1
ENST00000421033.1
ENST00000440291.1
ENST00000595813.1
ENST00000600574.1
ENST00000596051.1
ENST00000601110.1
ZNF415














zinc finger protein 415














chr19_-_54618650 0.429 ENST00000391757.1
TFPT
TCF3 (E2A) fusion partner (in childhood Leukemia)
chr3_-_164796269 0.417 ENST00000264382.3
SI
sucrase-isomaltase (alpha-glucosidase)
chr2_-_214013353 0.415 ENST00000451136.2
ENST00000421754.2
ENST00000374327.4
ENST00000413091.3
IKZF2



IKAROS family zinc finger 2 (Helios)



chr19_+_1440838 0.413 ENST00000594262.1
AC027307.3
Uncharacterized protein
chr14_+_73706308 0.407 ENST00000554301.1
ENST00000555445.1
PAPLN

papilin, proteoglycan-like sulfated glycoprotein

chr16_-_21663950 0.407 ENST00000268389.4
IGSF6
immunoglobulin superfamily, member 6
chr3_-_141747950 0.404 ENST00000497579.1
TFDP2
transcription factor Dp-2 (E2F dimerization partner 2)
chr2_+_28618532 0.402 ENST00000545753.1
FOSL2
FOS-like antigen 2
chr15_-_22448819 0.397 ENST00000604066.1
IGHV1OR15-1
immunoglobulin heavy variable 1/OR15-1 (non-functional)
chr2_-_209010874 0.394 ENST00000260988.4
CRYGB
crystallin, gamma B
chr4_-_76928641 0.393 ENST00000264888.5
CXCL9
chemokine (C-X-C motif) ligand 9
chr4_-_103998439 0.392 ENST00000503230.1
ENST00000503818.1
SLC9B2

solute carrier family 9, subfamily B (NHA2, cation proton antiporter 2), member 2

chr15_-_80263506 0.387 ENST00000335661.6
BCL2A1
BCL2-related protein A1
chr7_-_37026108 0.381 ENST00000396045.3
ELMO1
engulfment and cell motility 1
chr8_-_131399110 0.377 ENST00000521426.1
ASAP1
ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
chr12_-_6579833 0.375 ENST00000396308.3
VAMP1
vesicle-associated membrane protein 1 (synaptobrevin 1)
chr1_+_73771844 0.374 ENST00000440762.1
ENST00000444827.1
ENST00000415686.1
ENST00000411903.1
RP4-598G3.1



RP4-598G3.1



chr9_-_28670283 0.372 ENST00000379992.2
LINGO2
leucine rich repeat and Ig domain containing 2
chrX_+_135252050 0.371 ENST00000449474.1
ENST00000345434.3
FHL1

four and a half LIM domains 1

chr6_-_27114577 0.370 ENST00000356950.1
ENST00000396891.4
HIST1H2BK

histone cluster 1, H2bk

chr14_+_24540046 0.368 ENST00000397016.2
ENST00000537691.1
ENST00000560356.1
ENST00000558450.1
CPNE6



copine VI (neuronal)



chr6_-_27775694 0.366 ENST00000377401.2
HIST1H2BL
histone cluster 1, H2bl
chr1_+_154401791 0.365 ENST00000476006.1
IL6R
interleukin 6 receptor
chr7_+_134576317 0.361 ENST00000424922.1
ENST00000495522.1
CALD1

caldesmon 1

chr6_+_152011628 0.359 ENST00000404742.1
ENST00000440973.1
ESR1

estrogen receptor 1

chr12_-_30887948 0.358 ENST00000433722.2
CAPRIN2
caprin family member 2
chr9_+_125132803 0.357 ENST00000540753.1
PTGS1
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr19_-_54619006 0.355 ENST00000391759.1
TFPT
TCF3 (E2A) fusion partner (in childhood Leukemia)
chr20_-_46415341 0.354 ENST00000484875.1
ENST00000361612.4
SULF2

sulfatase 2

chr21_-_31864275 0.353 ENST00000334063.4
KRTAP19-3
keratin associated protein 19-3
chr3_+_111630451 0.352 ENST00000495180.1
PHLDB2
pleckstrin homology-like domain, family B, member 2
chr4_+_187148556 0.351 ENST00000264690.6
ENST00000446598.2
ENST00000414291.1
ENST00000513864.1
KLKB1



kallikrein B, plasma (Fletcher factor) 1



chr17_+_9728828 0.348 ENST00000262441.5
GLP2R
glucagon-like peptide 2 receptor
chr4_-_47983519 0.341 ENST00000358519.4
ENST00000544810.1
ENST00000402813.3
CNGA1


cyclic nucleotide gated channel alpha 1


chr15_-_58571445 0.340 ENST00000558231.1
ALDH1A2
aldehyde dehydrogenase 1 family, member A2
chr12_+_1800179 0.339 ENST00000357103.4
ADIPOR2
adiponectin receptor 2
chr3_-_37216055 0.339 ENST00000336686.4
LRRFIP2
leucine rich repeat (in FLII) interacting protein 2
chr1_-_152386732 0.337 ENST00000271835.3
CRNN
cornulin
chr2_+_101591314 0.335 ENST00000450763.1
NPAS2
neuronal PAS domain protein 2
chr11_+_63606373 0.333 ENST00000402010.2
ENST00000315032.8
ENST00000377809.4
ENST00000413835.2
ENST00000377810.3
MARK2




MAP/microtubule affinity-regulating kinase 2




chr14_-_72458326 0.330 ENST00000542853.1
AC005477.1
AC005477.1
chr9_-_114521783 0.329 ENST00000394779.3
ENST00000394777.4
C9orf84

chromosome 9 open reading frame 84

chrX_+_135251783 0.329 ENST00000394153.2
FHL1
four and a half LIM domains 1
chr11_+_124481361 0.329 ENST00000284288.2
PANX3
pannexin 3
chr20_-_1974692 0.323 ENST00000217305.2
ENST00000539905.1
PDYN

prodynorphin

chr3_-_108476231 0.323 ENST00000295755.6
RETNLB
resistin like beta
chr11_-_625163 0.320 ENST00000349570.7
CDHR5
cadherin-related family member 5
chr5_+_148521381 0.316 ENST00000504238.1
ABLIM3
actin binding LIM protein family, member 3
chr2_+_33359646 0.311 ENST00000390003.4
ENST00000418533.2
LTBP1

latent transforming growth factor beta binding protein 1

chr3_-_150690471 0.310 ENST00000468836.1
ENST00000328863.4
CLRN1

clarin 1

chr8_+_97597148 0.309 ENST00000521590.1
SDC2
syndecan 2
chr11_+_35201826 0.308 ENST00000531873.1
CD44
CD44 molecule (Indian blood group)
chr17_+_58018269 0.305 ENST00000591035.1
RP11-178C3.1
Uncharacterized protein
chrX_+_135251835 0.302 ENST00000456445.1
FHL1
four and a half LIM domains 1
chr2_+_33359687 0.300 ENST00000402934.1
ENST00000404525.1
ENST00000407925.1
LTBP1


latent transforming growth factor beta binding protein 1


chrX_-_18690210 0.300 ENST00000379984.3
RS1
retinoschisin 1
chr12_-_62586543 0.300 ENST00000416284.3
FAM19A2
family with sequence similarity 19 (chemokine (C-C motif)-like), member A2
chr11_-_107729887 0.300 ENST00000525815.1
SLC35F2
solute carrier family 35, member F2
chr20_-_5426332 0.299 ENST00000420529.1
LINC00658
long intergenic non-protein coding RNA 658
chr4_-_156787425 0.297 ENST00000537611.2
ASIC5
acid-sensing (proton-gated) ion channel family member 5
chr9_+_75229616 0.295 ENST00000340019.3
TMC1
transmembrane channel-like 1
chr3_-_185270342 0.294 ENST00000424591.2
LIPH
lipase, member H
chr1_+_948803 0.291 ENST00000379389.4
ISG15
ISG15 ubiquitin-like modifier
chr17_-_40575535 0.290 ENST00000357037.5
PTRF
polymerase I and transcript release factor
chr1_-_242162375 0.289 ENST00000357246.3
MAP1LC3C
microtubule-associated protein 1 light chain 3 gamma
chr19_+_7011509 0.288 ENST00000377296.3
AC025278.1
Uncharacterized protein
chr17_-_71410794 0.287 ENST00000424778.1
SDK2
sidekick cell adhesion molecule 2
chr1_+_70876926 0.286 ENST00000370938.3
ENST00000346806.2
CTH

cystathionase (cystathionine gamma-lyase)

chr9_-_21995249 0.284 ENST00000494262.1
CDKN2A
cyclin-dependent kinase inhibitor 2A
chr2_+_207024306 0.280 ENST00000236957.5
ENST00000392221.1
ENST00000392222.2
ENST00000445505.1
EEF1B2



eukaryotic translation elongation factor 1 beta 2



chr10_-_129691195 0.278 ENST00000368671.3
CLRN3
clarin 3
chr7_-_36634181 0.277 ENST00000538464.1
AOAH
acyloxyacyl hydrolase (neutrophil)
chr7_-_80551671 0.276 ENST00000419255.2
ENST00000544525.1
SEMA3C

sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C

chr17_-_39203519 0.274 ENST00000542137.1
ENST00000391419.3
KRTAP2-1

keratin associated protein 2-1

chr15_+_52155001 0.274 ENST00000544199.1
TMOD3
tropomodulin 3 (ubiquitous)
chr14_+_56584414 0.274 ENST00000559044.1
PELI2
pellino E3 ubiquitin protein ligase family member 2
chr9_-_95640218 0.272 ENST00000395506.3
ENST00000375495.3
ENST00000332591.6
ZNF484


zinc finger protein 484


chr9_+_116263778 0.271 ENST00000394646.3
RGS3
regulator of G-protein signaling 3
chr12_-_68619586 0.270 ENST00000229134.4
IL26
interleukin 26
chr17_-_39553844 0.268 ENST00000251645.2
KRT31
keratin 31
chr4_-_39033963 0.267 ENST00000381938.3
TMEM156
transmembrane protein 156
chr15_+_35270552 0.266 ENST00000391457.2
AC114546.1
HCG37415; PRO1914; Uncharacterized protein
chr8_+_104892639 0.265 ENST00000436393.2
RIMS2
regulating synaptic membrane exocytosis 2
chr4_-_69111401 0.263 ENST00000332644.5
TMPRSS11B
transmembrane protease, serine 11B
chr17_+_17082842 0.263 ENST00000579361.1
MPRIP
myosin phosphatase Rho interacting protein
chr11_-_125648690 0.263 ENST00000436890.2
ENST00000358524.3
PATE2

prostate and testis expressed 2

chr15_+_41549105 0.262 ENST00000560965.1
CHP1
calcineurin-like EF-hand protein 1
chr8_-_93029865 0.261 ENST00000422361.2
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr9_-_134145880 0.257 ENST00000372269.3
ENST00000464831.1
FAM78A

family with sequence similarity 78, member A

chrX_-_40506766 0.257 ENST00000378421.1
ENST00000440784.2
ENST00000327877.5
ENST00000378426.1
ENST00000378418.2
CXorf38




chromosome X open reading frame 38




chr2_+_234602305 0.256 ENST00000406651.1
UGT1A6
UDP glucuronosyltransferase 1 family, polypeptide A6
chr4_+_187187098 0.253 ENST00000403665.2
ENST00000264692.4
F11

coagulation factor XI

chr2_-_228497888 0.248 ENST00000264387.4
ENST00000409066.1
C2orf83

chromosome 2 open reading frame 83

chr6_+_153071925 0.247 ENST00000367244.3
ENST00000367243.3
VIP

vasoactive intestinal peptide

chr1_-_237167718 0.245 ENST00000464121.2
MT1HL1
metallothionein 1H-like 1
chr10_+_135160844 0.245 ENST00000423766.1
ENST00000458230.1
PRAP1

proline-rich acidic protein 1

chr19_+_4402659 0.243 ENST00000301280.5
ENST00000585854.1
CHAF1A

chromatin assembly factor 1, subunit A (p150)

chr7_-_72992865 0.240 ENST00000452475.1
TBL2
transducin (beta)-like 2
chr3_+_157827841 0.240 ENST00000295930.3
ENST00000471994.1
ENST00000464171.1
ENST00000312179.6
ENST00000475278.2
RSRC1




arginine/serine-rich coiled-coil 1




chr16_+_20775358 0.240 ENST00000440284.2
ACSM3
acyl-CoA synthetase medium-chain family member 3
chr4_-_22444733 0.239 ENST00000508133.1
GPR125
G protein-coupled receptor 125
chr20_+_42984330 0.239 ENST00000316673.4
ENST00000609795.1
ENST00000457232.1
ENST00000609262.1
HNF4A



hepatocyte nuclear factor 4, alpha



chr1_+_11539204 0.239 ENST00000294484.6
ENST00000389575.3
PTCHD2

patched domain containing 2

chrX_+_73164167 0.236 ENST00000414209.1
ENST00000602895.1
ENST00000453317.1
ENST00000602546.1
ENST00000602985.1
ENST00000415215.1
JPX





JPX transcript, XIST activator (non-protein coding)





chr15_-_99789736 0.234 ENST00000560235.1
ENST00000394132.2
ENST00000560860.1
ENST00000558078.1
ENST00000394136.1
ENST00000262074.4
ENST00000558613.1
ENST00000394130.1
ENST00000560772.1
TTC23








tetratricopeptide repeat domain 23








chr14_+_57671888 0.234 ENST00000391612.1
AL391152.1
AL391152.1
chr4_-_100065440 0.233 ENST00000508393.1
ENST00000265512.7
ADH4

alcohol dehydrogenase 4 (class II), pi polypeptide

chr7_-_111032971 0.232 ENST00000450877.1
IMMP2L
IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae)
chr1_+_23345943 0.232 ENST00000400181.4
ENST00000542151.1
KDM1A

lysine (K)-specific demethylase 1A

chr13_+_53030107 0.232 ENST00000490903.1
ENST00000480747.1
CKAP2

cytoskeleton associated protein 2

chr15_+_91411810 0.232 ENST00000268171.3
FURIN
furin (paired basic amino acid cleaving enzyme)
chr9_+_5450503 0.232 ENST00000381573.4
ENST00000381577.3
CD274

CD274 molecule

chr13_-_46679144 0.227 ENST00000181383.4
CPB2
carboxypeptidase B2 (plasma)
chr7_-_48068671 0.227 ENST00000297325.4
SUN3
Sad1 and UNC84 domain containing 3
chr6_+_12007963 0.227 ENST00000607445.1
RP11-456H18.2
RP11-456H18.2
chr8_-_49834299 0.225 ENST00000396822.1
SNAI2
snail family zinc finger 2
chr3_-_193272588 0.225 ENST00000295548.3
ATP13A4
ATPase type 13A4
chr1_+_23345930 0.225 ENST00000356634.3
KDM1A
lysine (K)-specific demethylase 1A
chr12_-_91546926 0.224 ENST00000550758.1
DCN
decorin
chr4_+_41258786 0.224 ENST00000503431.1
ENST00000284440.4
ENST00000508768.1
ENST00000512788.1
UCHL1



ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)



chr17_+_54230819 0.223 ENST00000318698.2
ENST00000566473.2
ANKFN1

ankyrin-repeat and fibronectin type III domain containing 1

chr3_-_178984759 0.223 ENST00000349697.2
ENST00000497599.1
KCNMB3

potassium large conductance calcium-activated channel, subfamily M beta member 3

chr1_-_168464875 0.222 ENST00000422253.1
RP5-968D22.3
RP5-968D22.3
chr4_-_76957214 0.222 ENST00000306621.3
CXCL11
chemokine (C-X-C motif) ligand 11
chr7_+_139529040 0.221 ENST00000455353.1
ENST00000458722.1
ENST00000411653.1
TBXAS1


thromboxane A synthase 1 (platelet)


chr12_+_75728419 0.221 ENST00000378695.4
ENST00000312442.2
GLIPR1L1

GLI pathogenesis-related 1 like 1

chr4_-_174320687 0.221 ENST00000296506.3
SCRG1
stimulator of chondrogenesis 1
chr13_-_47012325 0.221 ENST00000409879.2
KIAA0226L
KIAA0226-like
chr2_+_173600514 0.221 ENST00000264111.6
RAPGEF4
Rap guanine nucleotide exchange factor (GEF) 4
chr4_-_39979576 0.217 ENST00000303538.8
ENST00000503396.1
PDS5A

PDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae)

chr12_+_101988627 0.216 ENST00000547405.1
ENST00000452455.2
ENST00000441232.1
ENST00000360610.2
ENST00000392934.3
ENST00000547509.1
ENST00000361685.2
ENST00000549145.1
ENST00000553190.1
MYBPC1








myosin binding protein C, slow type








chr15_-_66797172 0.214 ENST00000569438.1
ENST00000569696.1
ENST00000307961.6
RPL4


ribosomal protein L4


chr9_+_21967137 0.214 ENST00000441769.2
C9orf53
chromosome 9 open reading frame 53
chr22_+_36113919 0.214 ENST00000249044.2
APOL5
apolipoprotein L, 5
chrX_+_99899180 0.214 ENST00000373004.3
SRPX2
sushi-repeat containing protein, X-linked 2
chr1_+_26485511 0.213 ENST00000374268.3
FAM110D
family with sequence similarity 110, member D
chr11_+_119019722 0.213 ENST00000307417.3
ABCG4
ATP-binding cassette, sub-family G (WHITE), member 4
chr12_-_10573149 0.213 ENST00000381904.2
ENST00000381903.2
ENST00000396439.2
KLRC3


killer cell lectin-like receptor subfamily C, member 3


chr2_-_88427568 0.212 ENST00000393750.3
ENST00000295834.3
FABP1

fatty acid binding protein 1, liver

chr13_-_46626847 0.211 ENST00000242848.4
ENST00000282007.3
ZC3H13

zinc finger CCCH-type containing 13


Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:0052047 interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047)
0.4 1.1 GO:0060585 regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.3 0.9 GO:0060279 regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.2 0.7 GO:0051919 positive regulation of fibrinolysis(GO:0051919)
0.2 1.1 GO:2000334 lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096) blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.1 0.4 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.1 0.1 GO:1904933 regulation of cell proliferation in midbrain(GO:1904933)
0.1 0.8 GO:0009082 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.1 0.4 GO:0017186 peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase(GO:0017186)
0.1 0.4 GO:0002384 hepatic immune response(GO:0002384)
0.1 0.4 GO:0003331 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.1 0.1 GO:1900158 negative regulation of bone mineralization involved in bone maturation(GO:1900158)
0.1 0.4 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.1 0.6 GO:0070649 polar body extrusion after meiotic divisions(GO:0040038) formin-nucleated actin cable assembly(GO:0070649)
0.1 0.7 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.1 0.2 GO:0061300 cerebellum vasculature development(GO:0061300)
0.1 0.2 GO:0032804 negative regulation of low-density lipoprotein particle receptor catabolic process(GO:0032804) negative regulation of neurotrophin production(GO:0032900) negative regulation of transforming growth factor beta1 production(GO:0032911)
0.1 0.5 GO:0046098 guanine metabolic process(GO:0046098)
0.1 0.2 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.1 0.2 GO:0007412 axon target recognition(GO:0007412)
0.1 0.9 GO:1904322 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.1 0.3 GO:0018352 protein-pyridoxal-5-phosphate linkage(GO:0018352)
0.1 0.6 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.1 0.6 GO:0038031 non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.1 0.6 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.1 0.2 GO:0001694 histamine biosynthetic process(GO:0001694)
0.1 0.5 GO:0002933 lipid hydroxylation(GO:0002933)
0.1 0.5 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.1 0.3 GO:0002370 natural killer cell cytokine production(GO:0002370) regulation of natural killer cell cytokine production(GO:0002727)
0.1 0.5 GO:2000543 positive regulation of gastrulation(GO:2000543)
0.1 0.2 GO:0090675 intermicrovillar adhesion(GO:0090675)
0.1 0.5 GO:0097338 response to clozapine(GO:0097338)
0.1 0.4 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
0.1 0.2 GO:0071934 thiamine transmembrane transport(GO:0071934)
0.1 0.5 GO:0035502 metanephric part of ureteric bud development(GO:0035502)
0.1 0.6 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.1 0.6 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.1 0.2 GO:1901228 positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation(GO:0003257) positive regulation of transcription from RNA polymerase II promoter involved in heart development(GO:1901228)
0.1 0.7 GO:0048263 determination of dorsal identity(GO:0048263)
0.1 0.4 GO:0070309 lens fiber cell morphogenesis(GO:0070309)
0.1 1.3 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.1 0.2 GO:0032641 lymphotoxin A production(GO:0032641) lymphotoxin A biosynthetic process(GO:0042109)
0.1 0.4 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.1 0.3 GO:0008218 bioluminescence(GO:0008218)
0.1 0.2 GO:1902044 regulation of Fas signaling pathway(GO:1902044)
0.0 0.2 GO:0007525 somatic muscle development(GO:0007525)
0.0 0.3 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.0 0.3 GO:0060005 vestibular reflex(GO:0060005)
0.0 1.1 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0 0.1 GO:0006145 purine nucleobase catabolic process(GO:0006145)
0.0 0.2 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.0 0.3 GO:0003350 pulmonary myocardium development(GO:0003350)
0.0 0.3 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 0.4 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.0 0.3 GO:1900623 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.0 0.5 GO:0048021 regulation of melanin biosynthetic process(GO:0048021) positive regulation of melanin biosynthetic process(GO:0048023) regulation of secondary metabolite biosynthetic process(GO:1900376) positive regulation of secondary metabolite biosynthetic process(GO:1900378)
0.0 0.6 GO:0035092 sperm chromatin condensation(GO:0035092)
0.0 0.6 GO:0090160 Golgi to lysosome transport(GO:0090160)
0.0 0.3 GO:0035799 ureter maturation(GO:0035799)
0.0 0.5 GO:0034214 protein hexamerization(GO:0034214)
0.0 0.6 GO:0035878 nail development(GO:0035878)
0.0 0.3 GO:0061588 calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylserine scrambling(GO:0061589) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591)
0.0 0.2 GO:0003051 angiotensin-mediated drinking behavior(GO:0003051)
0.0 0.4 GO:0060750 epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750) branch elongation involved in mammary gland duct branching(GO:0060751)
0.0 0.4 GO:0090646 mitochondrial tRNA processing(GO:0090646)
0.0 0.3 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 0.1 GO:0003050 regulation of systemic arterial blood pressure by atrial natriuretic peptide(GO:0003050)
0.0 0.2 GO:0033384 geranyl diphosphate metabolic process(GO:0033383) geranyl diphosphate biosynthetic process(GO:0033384) farnesyl diphosphate biosynthetic process(GO:0045337)
0.0 0.3 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.0 0.1 GO:0060474 positive regulation of sperm motility involved in capacitation(GO:0060474)
0.0 0.1 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.0 0.1 GO:0035964 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.0 0.0 GO:0070560 protein secretion by platelet(GO:0070560)
0.0 0.2 GO:0006021 inositol biosynthetic process(GO:0006021)
0.0 0.4 GO:0052696 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.0 0.2 GO:2001181 positive regulation of interleukin-10 secretion(GO:2001181)
0.0 0.3 GO:0061669 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.0 0.3 GO:0032417 positive regulation of sodium:proton antiporter activity(GO:0032417) negative regulation of calcineurin-NFAT signaling cascade(GO:0070885)
0.0 0.1 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.0 0.1 GO:0010896 regulation of triglyceride catabolic process(GO:0010896) positive regulation of triglyceride catabolic process(GO:0010898)
0.0 0.1 GO:0007037 vacuolar phosphate transport(GO:0007037) positive regulation of mitotic cell cycle DNA replication(GO:1903465) positive regulation of parathyroid hormone secretion(GO:2000830)
0.0 0.2 GO:0060478 acrosomal vesicle exocytosis(GO:0060478)
0.0 0.3 GO:0050957 equilibrioception(GO:0050957)
0.0 0.2 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.0 0.1 GO:0045338 farnesyl diphosphate metabolic process(GO:0045338)
0.0 0.1 GO:0048213 Golgi vesicle prefusion complex stabilization(GO:0048213)
0.0 0.2 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.0 0.5 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.1 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
0.0 0.1 GO:0019285 glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456)
0.0 0.1 GO:0002881 negative regulation of chronic inflammatory response to non-antigenic stimulus(GO:0002881)
0.0 0.2 GO:0010579 regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010578) positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010579)
0.0 0.2 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.2 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
0.0 0.3 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.1 GO:0019442 tryptophan catabolic process to acetyl-CoA(GO:0019442)
0.0 0.2 GO:0010269 response to selenium ion(GO:0010269)
0.0 0.1 GO:0002331 pre-B cell allelic exclusion(GO:0002331)
0.0 0.5 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.3 GO:0098828 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0 0.7 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.1 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.0 1.1 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.3 GO:0015992 proton transport(GO:0015992)
0.0 0.1 GO:0097360 chorionic trophoblast cell proliferation(GO:0097360) regulation of chorionic trophoblast cell proliferation(GO:1901382)
0.0 0.1 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 0.2 GO:0038129 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842) ERBB3 signaling pathway(GO:0038129)
0.0 0.1 GO:0050916 sensory perception of sweet taste(GO:0050916) sensory perception of umami taste(GO:0050917)
0.0 0.3 GO:2000111 senescence-associated heterochromatin focus assembly(GO:0035986) positive regulation of macrophage apoptotic process(GO:2000111)
0.0 4.6 GO:0031424 keratinization(GO:0031424)
0.0 0.2 GO:0048539 bone marrow development(GO:0048539)
0.0 0.1 GO:0010982 regulation of high-density lipoprotein particle clearance(GO:0010982)
0.0 0.2 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.4 GO:0006069 ethanol oxidation(GO:0006069)
0.0 0.4 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.1 GO:0097156 fasciculation of motor neuron axon(GO:0097156)
0.0 0.3 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0 0.1 GO:1904970 brush border assembly(GO:1904970)
0.0 0.2 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.0 0.1 GO:0051799 negative regulation of hair follicle development(GO:0051799)
0.0 0.2 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 0.2 GO:0035881 amacrine cell differentiation(GO:0035881)
0.0 0.0 GO:1900226 negative regulation of NLRP3 inflammasome complex assembly(GO:1900226)
0.0 0.4 GO:0051901 positive regulation of mitochondrial depolarization(GO:0051901)
0.0 0.4 GO:0002227 innate immune response in mucosa(GO:0002227)
0.0 0.2 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.0 0.1 GO:1902490 regulation of sperm capacitation(GO:1902490)
0.0 0.1 GO:1902358 sulfate transmembrane transport(GO:1902358)
0.0 0.6 GO:0010842 retina layer formation(GO:0010842)
0.0 0.1 GO:2000296 negative regulation of hydrogen peroxide catabolic process(GO:2000296)
0.0 0.1 GO:0030047 actin modification(GO:0030047)
0.0 0.3 GO:0051775 response to redox state(GO:0051775)
0.0 0.1 GO:0061113 pancreas morphogenesis(GO:0061113)
0.0 0.1 GO:1990737 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394) response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.0 0.1 GO:1902227 negative regulation of macrophage colony-stimulating factor signaling pathway(GO:1902227) negative regulation of response to macrophage colony-stimulating factor(GO:1903970) negative regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903973) regulation of microglial cell activation(GO:1903978)
0.0 0.2 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.0 0.2 GO:0002726 positive regulation of T cell cytokine production(GO:0002726)
0.0 0.1 GO:0090131 mesenchyme migration(GO:0090131)
0.0 0.1 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.0 0.1 GO:0090309 positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.0 0.4 GO:0001522 pseudouridine synthesis(GO:0001522)
0.0 0.0 GO:1903056 regulation of melanosome transport(GO:1902908) regulation of melanosome organization(GO:1903056)
0.0 0.1 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
0.0 0.1 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.0 0.2 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 1.0 GO:0043268 positive regulation of potassium ion transport(GO:0043268)
0.0 0.1 GO:0032098 regulation of appetite(GO:0032098)
0.0 0.3 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.2 GO:1904778 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.0 0.1 GO:0051414 response to cortisol(GO:0051414)
0.0 0.1 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.0 0.0 GO:0044691 tooth eruption(GO:0044691)
0.0 0.5 GO:0072698 protein localization to microtubule cytoskeleton(GO:0072698)
0.0 0.0 GO:0002125 maternal aggressive behavior(GO:0002125) positive regulation of female receptivity(GO:0045925)
0.0 0.0 GO:0031247 actin rod assembly(GO:0031247)
0.0 0.4 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.0 0.1 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.0 0.1 GO:1903244 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244)
0.0 0.1 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.0 0.1 GO:0048845 venous blood vessel morphogenesis(GO:0048845)
0.0 0.1 GO:0000393 spliceosomal conformational changes to generate catalytic conformation(GO:0000393)
0.0 0.4 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 0.4 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.0 0.0 GO:2000342 negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342)
0.0 0.0 GO:1901876 regulation of the force of heart contraction by cardiac conduction(GO:0086092) regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877) regulation of calcium ion import into sarcoplasmic reticulum(GO:1902080) negative regulation of calcium ion import into sarcoplasmic reticulum(GO:1902081)
0.0 0.0 GO:2000302 positive regulation of synaptic vesicle exocytosis(GO:2000302)
0.0 0.2 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.0 GO:0045876 positive regulation of sister chromatid cohesion(GO:0045876)
0.0 0.2 GO:0030502 negative regulation of bone mineralization(GO:0030502)
0.0 0.1 GO:0000414 regulation of histone H3-K36 methylation(GO:0000414)
0.0 0.1 GO:0098704 fructose transport(GO:0015755) fructose import(GO:0032445) carbohydrate import into cell(GO:0097319) carbohydrate import across plasma membrane(GO:0098704) fructose import across plasma membrane(GO:1990539)
0.0 0.4 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
0.0 0.6 GO:0048599 oocyte development(GO:0048599)
0.0 0.1 GO:0015742 alpha-ketoglutarate transport(GO:0015742)
0.0 0.4 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.9 GO:0046847 filopodium assembly(GO:0046847)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0043511 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.3 1.1 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.3 1.3 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.2 0.7 GO:0033150 cytoskeletal calyx(GO:0033150)
0.1 0.4 GO:0005588 collagen type V trimer(GO:0005588)
0.1 1.8 GO:0005577 fibrinogen complex(GO:0005577)
0.1 1.9 GO:0030478 actin cap(GO:0030478)
0.1 0.6 GO:0020018 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.1 0.4 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.1 0.2 GO:0033186 CAF-1 complex(GO:0033186)
0.1 0.4 GO:0030678 mitochondrial ribonuclease P complex(GO:0030678)
0.1 0.7 GO:0005642 annulate lamellae(GO:0005642)
0.0 0.3 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.0 0.2 GO:0089717 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.0 0.3 GO:0097427 microtubule bundle(GO:0097427)
0.0 0.4 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.0 0.9 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.1 GO:0001674 female germ cell nucleus(GO:0001674)
0.0 0.1 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
0.0 0.2 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 1.0 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.6 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.5 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 0.3 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.4 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 4.6 GO:0005882 intermediate filament(GO:0005882)
0.0 0.6 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.5 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.3 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.0 0.7 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 0.2 GO:0043541 UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.0 0.3 GO:0032426 stereocilium tip(GO:0032426)
0.0 0.3 GO:0033093 Weibel-Palade body(GO:0033093)
0.0 0.2 GO:0097486 multivesicular body lumen(GO:0097486)
0.0 0.4 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.1 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.2 GO:0070852 cell body fiber(GO:0070852)
0.0 0.3 GO:0045180 basal cortex(GO:0045180)
0.0 0.7 GO:0097228 sperm principal piece(GO:0097228)
0.0 0.2 GO:0045179 apical cortex(GO:0045179)
0.0 0.3 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.1 GO:0036128 CatSper complex(GO:0036128)
0.0 0.0 GO:0000836 Hrd1p ubiquitin ligase complex(GO:0000836)
0.0 0.1 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.0 0.7 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 1.1 GO:0000786 nucleosome(GO:0000786)
0.0 0.1 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.0 0.2 GO:0008091 spectrin(GO:0008091)
0.0 0.1 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 0.5 GO:0005921 gap junction(GO:0005921)
0.0 0.1 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.0 0.1 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.0 0.1 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.2 GO:0032433 filopodium tip(GO:0032433)
0.0 0.1 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.1 GO:0034715 pICln-Sm protein complex(GO:0034715)
0.0 0.6 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.2 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 0.1 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.0 0.2 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.9 GO:0043195 terminal bouton(GO:0043195)
0.0 0.3 GO:0030673 axolemma(GO:0030673)
0.0 0.1 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.1 GO:1990635 proximal dendrite(GO:1990635)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0047223 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity(GO:0047223)
0.3 0.9 GO:0070699 type II activin receptor binding(GO:0070699)
0.2 1.1 GO:0031708 endothelin B receptor binding(GO:0031708)
0.2 1.3 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.2 1.1 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.2 0.7 GO:0005503 all-trans retinal binding(GO:0005503)
0.2 0.5 GO:0050528 acyloxyacyl hydrolase activity(GO:0050528)
0.2 0.5 GO:0061752 telomeric repeat-containing RNA binding(GO:0061752)
0.1 0.7 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.1 0.4 GO:0036134 thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
0.1 0.6 GO:0010348 lithium:proton antiporter activity(GO:0010348)
0.1 0.4 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.1 0.8 GO:0052654 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.1 0.4 GO:0016603 glutaminyl-peptide cyclotransferase activity(GO:0016603)
0.1 0.6 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.1 0.6 GO:0050436 microfibril binding(GO:0050436)
0.1 0.4 GO:0019981 interleukin-6 receptor activity(GO:0004915) interleukin-6 binding(GO:0019981)
0.1 0.3 GO:0004967 glucagon receptor activity(GO:0004967)
0.1 0.4 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.1 0.5 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.1 0.2 GO:0015403 thiamine uptake transmembrane transporter activity(GO:0015403)
0.1 0.4 GO:0005499 vitamin D binding(GO:0005499)
0.1 0.2 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.1 2.2 GO:0005523 tropomyosin binding(GO:0005523)
0.1 1.0 GO:0030280 structural constituent of epidermis(GO:0030280)
0.1 1.0 GO:0005132 type I interferon receptor binding(GO:0005132)
0.1 0.5 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.1 0.4 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 1.5 GO:0004806 triglyceride lipase activity(GO:0004806)
0.1 0.2 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.1 0.3 GO:0001515 opioid peptide activity(GO:0001515)
0.1 0.9 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.3 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.0 0.2 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.0 0.4 GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.0 0.2 GO:0052832 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.0 0.2 GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.0 0.2 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.0 0.2 GO:0004337 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.0 0.2 GO:0034875 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.0 1.0 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.7 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 0.1 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 0.2 GO:0015085 calcium-transporting ATPase activity(GO:0005388) calcium ion transmembrane transporter activity(GO:0015085)
0.0 0.6 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.1 GO:0051996 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.0 0.2 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.0 0.2 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.3 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 0.3 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.0 0.5 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.1 GO:0016495 C-X3-C chemokine receptor activity(GO:0016495)
0.0 1.7 GO:0016504 peptidase activator activity(GO:0016504)
0.0 0.2 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.0 0.6 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.5 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.4 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.1 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.0 0.2 GO:0042731 PH domain binding(GO:0042731)
0.0 0.3 GO:0031386 protein tag(GO:0031386)
0.0 0.2 GO:0008035 high-density lipoprotein particle binding(GO:0008035)
0.0 0.1 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.0 0.4 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)
0.0 0.6 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.1 GO:0005502 11-cis retinal binding(GO:0005502)
0.0 0.2 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.3 GO:0043855 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0 0.2 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.0 0.4 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.1 GO:0016503 pheromone receptor activity(GO:0016503)
0.0 0.5 GO:0051400 BH domain binding(GO:0051400)
0.0 0.2 GO:0070728 leucine binding(GO:0070728)
0.0 0.1 GO:0005260 channel-conductance-controlling ATPase activity(GO:0005260)
0.0 0.1 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.0 0.1 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.0 0.2 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 0.4 GO:0031432 titin binding(GO:0031432)
0.0 0.3 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.3 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.1 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.2 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.0 1.4 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.2 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 0.4 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.3 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.3 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.1 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0 0.0 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.7 GO:0005109 frizzled binding(GO:0005109)
0.0 0.1 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
0.0 0.4 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.3 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.1 GO:0031994 insulin-like growth factor I binding(GO:0031994)
0.0 0.1 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.0 0.2 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 0.1 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.0 0.1 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.0 0.1 GO:0043546 molybdopterin cofactor binding(GO:0043546)
0.0 0.2 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.0 0.2 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.2 GO:0097109 neuroligin family protein binding(GO:0097109)
0.0 0.2 GO:0008061 chitin binding(GO:0008061)
0.0 0.1 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.0 0.3 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.4 GO:0030275 LRR domain binding(GO:0030275)
0.0 0.1 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
0.0 0.9 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.4 GO:0031489 myosin V binding(GO:0031489)
0.0 0.3 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.1 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.0 0.5 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.1 GO:0004977 melanocortin receptor activity(GO:0004977)
0.0 0.4 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.0 GO:0031071 cysteine desulfurase activity(GO:0031071)
0.0 0.3 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.0 0.1 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.0 0.4 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.1 GO:0015140 malate transmembrane transporter activity(GO:0015140)
0.0 0.4 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.2 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.1 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.1 GO:0005353 fructose transmembrane transporter activity(GO:0005353)
0.0 0.1 GO:0004630 phospholipase D activity(GO:0004630)
0.0 0.0 GO:0004087 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.0 0.0 GO:0050571 1,5-anhydro-D-fructose reductase activity(GO:0050571)
0.0 0.0 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.0 0.4 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.1 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.0 0.2 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.1 GO:0032564 adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
0.0 0.1 GO:0004064 arylesterase activity(GO:0004064)
0.0 0.2 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.2 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 3.1 GO:0004252 serine-type endopeptidase activity(GO:0004252)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.7 PID_INTEGRIN5_PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 1.0 PID_LPA4_PATHWAY LPA4-mediated signaling events
0.0 0.7 SA_MMP_CYTOKINE_CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 1.3 PID_FRA_PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.6 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.0 1.8 PID_HIF1_TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.6 PID_ALK1_PATHWAY ALK1 signaling events
0.0 0.4 PID_ARF_3PATHWAY Arf1 pathway
0.0 0.3 PID_CIRCADIAN_PATHWAY Circadian rhythm pathway
0.0 0.5 PID_P38_MKK3_6PATHWAY p38 MAPK signaling pathway
0.0 1.0 PID_TCR_PATHWAY TCR signaling in naïve CD4+ T cells
0.0 0.3 PID_INTEGRIN_A9B1_PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.8 PID_CD8_TCR_DOWNSTREAM_PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 0.6 PID_IL23_PATHWAY IL23-mediated signaling events
0.0 0.6 PID_NETRIN_PATHWAY Netrin-mediated signaling events
0.0 0.5 PID_GMCSF_PATHWAY GMCSF-mediated signaling events
0.0 0.6 PID_TNF_PATHWAY TNF receptor signaling pathway
0.0 0.5 PID_KIT_PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.4 PID_ALPHA_SYNUCLEIN_PATHWAY Alpha-synuclein signaling
0.0 0.3 PID_SYNDECAN_2_PATHWAY Syndecan-2-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 REACTOME_ADENYLATE_CYCLASE_ACTIVATING_PATHWAY Genes involved in Adenylate cyclase activating pathway
0.1 1.7 REACTOME_GRB2_SOS_PROVIDES_LINKAGE_TO_MAPK_SIGNALING_FOR_INTERGRINS_ Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 1.0 REACTOME_SIGNAL_REGULATORY_PROTEIN_SIRP_FAMILY_INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.6 REACTOME_GLYCOPROTEIN_HORMONES Genes involved in Glycoprotein hormones
0.0 0.7 REACTOME_INTRINSIC_PATHWAY Genes involved in Intrinsic Pathway
0.0 0.4 REACTOME_IL_6_SIGNALING Genes involved in Interleukin-6 signaling
0.0 2.0 REACTOME_SMOOTH_MUSCLE_CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 1.2 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions
0.0 1.3 REACTOME_PACKAGING_OF_TELOMERE_ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.4 REACTOME_ETHANOL_OXIDATION Genes involved in Ethanol oxidation
0.0 0.8 REACTOME_REGULATION_OF_IFNA_SIGNALING Genes involved in Regulation of IFNA signaling
0.0 0.9 REACTOME_PTM_GAMMA_CARBOXYLATION_HYPUSINE_FORMATION_AND_ARYLSULFATASE_ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 0.6 REACTOME_PKA_MEDIATED_PHOSPHORYLATION_OF_CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 0.6 REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.4 REACTOME_DOPAMINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.0 0.3 REACTOME_IRAK1_RECRUITS_IKK_COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 0.2 REACTOME_IRAK2_MEDIATED_ACTIVATION_OF_TAK1_COMPLEX_UPON_TLR7_8_OR_9_STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.5 REACTOME_GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.2 REACTOME_SEROTONIN_RECEPTORS Genes involved in Serotonin receptors
0.0 0.4 REACTOME_ZINC_TRANSPORTERS Genes involved in Zinc transporters
0.0 0.3 REACTOME_G_PROTEIN_ACTIVATION Genes involved in G-protein activation
0.0 0.3 REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_GLUCAGON_LIKE_PEPTIDE1 Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.0 0.3 REACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.4 REACTOME_PROTEOLYTIC_CLEAVAGE_OF_SNARE_COMPLEX_PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.7 REACTOME_A_TETRASACCHARIDE_LINKER_SEQUENCE_IS_REQUIRED_FOR_GAG_SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 1.9 REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 1.1 REACTOME_PHASE1_FUNCTIONALIZATION_OF_COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.0 0.2 REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.6 REACTOME_MUSCLE_CONTRACTION Genes involved in Muscle contraction
0.0 0.2 REACTOME_P2Y_RECEPTORS Genes involved in P2Y receptors
0.0 0.4 REACTOME_DOWNREGULATION_OF_TGF_BETA_RECEPTOR_SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 1.8 REACTOME_PPARA_ACTIVATES_GENE_EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.7 REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES Genes involved in Chemokine receptors bind chemokines