Motif ID: HOXD9

Z-value: 0.576


Transcription factors associated with HOXD9:

Gene SymbolEntrez IDGene Name
HOXD9 ENSG00000128709.10 HOXD9

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
HOXD9hg19_v2_chr2_+_176987088_176987088-0.106.5e-01Click!


Activity profile for motif HOXD9.

activity profile for motif HOXD9


Sorted Z-values histogram for motif HOXD9

Sorted Z-values for motif HOXD9



Network of associatons between targets according to the STRING database.



First level regulatory network of HOXD9

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_-_197036364 1.203 ENST00000367412.1
F13B
coagulation factor XIII, B polypeptide
chr17_+_68071389 1.160 ENST00000283936.1
ENST00000392671.1
KCNJ16

potassium inwardly-rectifying channel, subfamily J, member 16

chr17_+_68071458 1.135 ENST00000589377.1
KCNJ16
potassium inwardly-rectifying channel, subfamily J, member 16
chr7_-_16921601 1.071 ENST00000402239.3
ENST00000310398.2
ENST00000414935.1
AGR3


anterior gradient 3


chr3_-_112564797 1.022 ENST00000398214.1
ENST00000448932.1
CD200R1L

CD200 receptor 1-like

chr6_-_52774464 0.993 ENST00000370968.1
ENST00000211122.3
GSTA3

glutathione S-transferase alpha 3

chr5_+_68860949 0.968 ENST00000507595.1
GTF2H2C
general transcription factor IIH, polypeptide 2C
chr5_+_94727048 0.810 ENST00000283357.5
FAM81B
family with sequence similarity 81, member B
chr4_+_71108300 0.808 ENST00000304954.3
CSN3
casein kappa
chr22_+_23487513 0.766 ENST00000263116.2
ENST00000341989.4
RAB36

RAB36, member RAS oncogene family

chr2_-_158345462 0.761 ENST00000439355.1
ENST00000540637.1
CYTIP

cytohesin 1 interacting protein

chr1_+_38022513 0.750 ENST00000296218.7
DNALI1
dynein, axonemal, light intermediate chain 1
chr10_-_71169031 0.716 ENST00000373307.1
TACR2
tachykinin receptor 2
chr4_-_110723194 0.714 ENST00000394635.3
CFI
complement factor I
chr2_-_231989808 0.690 ENST00000258400.3
HTR2B
5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
chr5_-_41261540 0.672 ENST00000263413.3
C6
complement component 6
chr9_-_39239171 0.662 ENST00000358144.2
CNTNAP3
contactin associated protein-like 3
chr9_-_138391692 0.650 ENST00000429260.2
C9orf116
chromosome 9 open reading frame 116
chr17_+_9479944 0.648 ENST00000396219.3
ENST00000352665.5
WDR16

WD repeat domain 16

chr2_+_143886877 0.647 ENST00000295095.6
ARHGAP15
Rho GTPase activating protein 15

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 52 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.5 GO:0010107 potassium ion import(GO:0010107)
0.0 1.0 GO:1901685 glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
0.1 0.9 GO:1990034 cellular response to corticosterone stimulus(GO:0071386) calcium ion export from cell(GO:1990034)
0.0 0.8 GO:0007595 lactation(GO:0007595)
0.2 0.7 GO:0014057 positive regulation of acetylcholine secretion, neurotransmission(GO:0014057)
0.2 0.7 GO:0001970 positive regulation of activation of membrane attack complex(GO:0001970)
0.1 0.7 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.2 0.6 GO:0051758 homologous chromosome movement towards spindle pole involved in homologous chromosome segregation(GO:0051758)
0.1 0.6 GO:0048023 positive regulation of melanin biosynthetic process(GO:0048023) positive regulation of secondary metabolite biosynthetic process(GO:1900378)
0.0 0.6 GO:0045745 positive regulation of G-protein coupled receptor protein signaling pathway(GO:0045745)
0.0 0.5 GO:0015671 oxygen transport(GO:0015671)
0.0 0.5 GO:0044458 motile cilium assembly(GO:0044458)
0.0 0.5 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.0 0.4 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.4 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.1 0.3 GO:0052314 phytoalexin metabolic process(GO:0052314)
0.1 0.3 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.1 0.3 GO:0001983 regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback(GO:0001978) baroreceptor response to increased systemic arterial blood pressure(GO:0001983) positive regulation of the force of heart contraction by chemical signal(GO:0003099)
0.1 0.3 GO:0042214 terpene metabolic process(GO:0042214)
0.1 0.3 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 22 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.2 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 1.5 GO:0097014 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.1 1.0 GO:0000439 core TFIIH complex(GO:0000439)
0.0 0.9 GO:0032591 dendritic spine membrane(GO:0032591)
0.1 0.8 GO:0005579 membrane attack complex(GO:0005579)
0.1 0.6 GO:1990111 spermatoproteasome complex(GO:1990111)
0.0 0.6 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 0.5 GO:1990423 RZZ complex(GO:1990423)
0.1 0.5 GO:0097224 sperm connecting piece(GO:0097224)
0.0 0.5 GO:0005833 hemoglobin complex(GO:0005833)
0.0 0.5 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.4 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 0.3 GO:0097179 NLRP1 inflammasome complex(GO:0072558) protease inhibitor complex(GO:0097179)
0.0 0.3 GO:0033269 internode region of axon(GO:0033269)
0.0 0.3 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.2 GO:0071439 clathrin complex(GO:0071439)
0.0 0.1 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 0.1 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.0 0.1 GO:0070081 clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.0 0.1 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 39 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.3 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 1.0 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.9 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.8 GO:0045504 dynein heavy chain binding(GO:0045504)
0.1 0.7 GO:0004995 tachykinin receptor activity(GO:0004995)
0.1 0.7 GO:0034711 inhibin binding(GO:0034711)
0.1 0.7 GO:0043176 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0 0.7 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.6 GO:0032395 MHC class II receptor activity(GO:0032395)
0.0 0.6 GO:0005549 odorant binding(GO:0005549)
0.0 0.6 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.6 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.1 0.5 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.0 0.5 GO:0032027 myosin light chain binding(GO:0032027)
0.0 0.5 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 0.5 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 0.4 GO:0019959 interleukin-8 binding(GO:0019959)
0.1 0.3 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.1 0.3 GO:0004948 calcitonin receptor activity(GO:0004948)
0.1 0.3 GO:0035529 NADH pyrophosphatase activity(GO:0035529)

Gene overrepresentation in C2:CP category:

Showing 1 to 1 of 1 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.6 PID_CONE_PATHWAY Visual signal transduction: Cones

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 11 of 11 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.0 REACTOME_INHIBITION_OF_VOLTAGE_GATED_CA2_CHANNELS_VIA_GBETA_GAMMA_SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 1.3 REACTOME_COMPLEMENT_CASCADE Genes involved in Complement cascade
0.1 1.2 REACTOME_COMMON_PATHWAY Genes involved in Common Pathway
0.0 1.0 REACTOME_GLUTATHIONE_CONJUGATION Genes involved in Glutathione conjugation
0.0 0.7 REACTOME_SEROTONIN_RECEPTORS Genes involved in Serotonin receptors
0.0 0.4 REACTOME_HDL_MEDIATED_LIPID_TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.4 REACTOME_AMINE_LIGAND_BINDING_RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.4 REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.3 REACTOME_THE_NLRP3_INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.3 REACTOME_AMINE_DERIVED_HORMONES Genes involved in Amine-derived hormones
0.0 0.1 REACTOME_INWARDLY_RECTIFYING_K_CHANNELS Genes involved in Inwardly rectifying K+ channels