Motif ID: JDP2

Z-value: 0.587


Transcription factors associated with JDP2:

Gene SymbolEntrez IDGene Name
JDP2 ENSG00000140044.8 JDP2



Activity profile for motif JDP2.

activity profile for motif JDP2


Sorted Z-values histogram for motif JDP2

Sorted Z-values for motif JDP2



Network of associatons between targets according to the STRING database.



First level regulatory network of JDP2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chrY_+_15016725 1.610 ENST00000336079.3
 DDX3Y
DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
chr11_-_102668879 1.064 ENST00000315274.6
 MMP1
matrix metallopeptidase 1 (interstitial collagenase)
chr10_+_17270214 1.017 ENST00000544301.1
 VIM
vimentin
chr12_+_7023735 0.966 ENST00000538763.1
ENST00000544774.1
ENST00000545045.2
 ENO2


enolase 2 (gamma, neuronal)


chr12_+_7023491 0.962 ENST00000541477.1
ENST00000229277.1
 ENO2

enolase 2 (gamma, neuronal)

chr9_-_124991124 0.868 ENST00000394319.4
ENST00000340587.3
 LHX6

LIM homeobox 6

chr13_+_32838801 0.700 ENST00000542859.1
 FRY
furry homolog (Drosophila)
chr9_-_123638633 0.696 ENST00000456291.1
 PHF19
PHD finger protein 19
chr9_-_123639304 0.678 ENST00000436309.1
 PHF19
PHD finger protein 19
chr2_+_10262442 0.645 ENST00000360566.2
 RRM2
ribonucleotide reductase M2
chr16_+_15596123 0.588 ENST00000452191.2
 C16orf45
chromosome 16 open reading frame 45
chr17_+_4853442 0.584 ENST00000522301.1
 ENO3
enolase 3 (beta, muscle)
chr10_+_127661942 0.582 ENST00000417114.1
ENST00000445510.1
ENST00000368691.1
 FANK1


fibronectin type III and ankyrin repeat domains 1


chr20_-_17539456 0.579 ENST00000544874.1
ENST00000377868.2
 BFSP1

beaded filament structural protein 1, filensin

chr19_-_36019123 0.575 ENST00000588674.1
ENST00000452271.2
ENST00000518157.1
 SBSN


suprabasin


chr19_-_35992780 0.551 ENST00000593342.1
ENST00000601650.1
ENST00000408915.2
 DMKN


dermokine


chr7_+_97361388 0.516 ENST00000350485.4
ENST00000346867.4
 TAC1

tachykinin, precursor 1

chr1_-_153521597 0.506 ENST00000368712.1
 S100A3
S100 calcium binding protein A3
chr7_+_97361218 0.499 ENST00000319273.5
 TAC1
tachykinin, precursor 1
chr1_-_153521714 0.473 ENST00000368713.3
 S100A3
S100 calcium binding protein A3

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 55 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.9 GO:0061718 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.1 1.6 GO:0070307 lens fiber cell development(GO:0070307)
0.1 1.4 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.1 1.4 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 1.3 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 1.1 GO:0032461 positive regulation of protein oligomerization(GO:0032461)
0.3 1.0 GO:2000854 positive regulation of corticosterone secretion(GO:2000854)
0.2 1.0 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.1 0.9 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.1 0.9 GO:0044351 macropinocytosis(GO:0044351) phagosome-lysosome fusion(GO:0090385)
0.0 0.9 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.3 0.8 GO:1903568 negative regulation of protein localization to cilium(GO:1903565) regulation of protein localization to ciliary membrane(GO:1903567) negative regulation of protein localization to ciliary membrane(GO:1903568)
0.1 0.7 GO:0090043 regulation of tubulin deacetylation(GO:0090043)
0.2 0.6 GO:0006218 uridine catabolic process(GO:0006218)
0.1 0.6 GO:1903976 negative regulation of glial cell migration(GO:1903976)
0.1 0.6 GO:1903575 cornified envelope assembly(GO:1903575)
0.0 0.6 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.0 0.5 GO:0014046 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.1 0.4 GO:0033123 positive regulation of cyclic nucleotide catabolic process(GO:0030807) positive regulation of cAMP catabolic process(GO:0030822) positive regulation of purine nucleotide catabolic process(GO:0033123)
0.1 0.4 GO:0044805 late nucleophagy(GO:0044805)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 20 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 2.5 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 1.4 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 1.0 GO:0015030 Cajal body(GO:0015030)
0.1 0.6 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.1 0.4 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0 0.4 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.4 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.4 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.3 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.0 0.3 GO:0097418 neurofibrillary tangle(GO:0097418)
0.0 0.2 GO:0070545 PeBoW complex(GO:0070545)
0.0 0.2 GO:0042587 glycogen granule(GO:0042587)
0.0 0.1 GO:0097489 multivesicular body, internal vesicle lumen(GO:0097489)
0.0 0.1 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.0 0.1 GO:0005607 laminin-2 complex(GO:0005607)
0.0 0.1 GO:0030934 anchoring collagen complex(GO:0030934)
0.0 0.1 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.0 0.1 GO:0031673 H zone(GO:0031673)
0.0 0.1 GO:0005610 laminin-5 complex(GO:0005610)
0.0 0.0 GO:0033565 ESCRT-0 complex(GO:0033565)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 34 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 2.5 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 1.4 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.0 1.4 GO:0035064 methylated histone binding(GO:0035064)
0.0 1.3 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004)
0.3 1.0 GO:0008859 exoribonuclease II activity(GO:0008859)
0.1 1.0 GO:1990254 keratin filament binding(GO:1990254)
0.0 1.0 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.0 0.9 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.9 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.1 0.6 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.1 0.6 GO:0004850 uridine phosphorylase activity(GO:0004850)
0.0 0.6 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.5 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.4 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.4 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.0 0.4 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.4 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.4 GO:0042605 peptide antigen binding(GO:0042605)
0.1 0.3 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.3 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)

Gene overrepresentation in C2:CP category:

Showing 1 to 7 of 7 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.9 PID_SYNDECAN_1_PATHWAY Syndecan-1-mediated signaling events
0.0 0.8 PID_AURORA_B_PATHWAY Aurora B signaling
0.0 0.6 PID_INTEGRIN_CS_PATHWAY Integrin family cell surface interactions
0.0 0.4 ST_G_ALPHA_S_PATHWAY G alpha s Pathway
0.0 0.4 PID_ARF6_DOWNSTREAM_PATHWAY Arf6 downstream pathway
0.0 0.4 PID_LPA4_PATHWAY LPA4-mediated signaling events
0.0 0.2 PID_INTEGRIN4_PATHWAY Alpha6 beta4 integrin-ligand interactions

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 17 of 17 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.9 REACTOME_GLYCOLYSIS Genes involved in Glycolysis
0.1 1.4 REACTOME_SYNTHESIS_OF_PE Genes involved in Synthesis of PE
0.0 1.1 REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 1.0 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 1.0 REACTOME_SYNTHESIS_OF_PA Genes involved in Synthesis of PA
0.0 1.0 REACTOME_INTERFERON_ALPHA_BETA_SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.6 REACTOME_PYRIMIDINE_CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.6 REACTOME_G1_S_SPECIFIC_TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 0.6 REACTOME_APOPTOTIC_CLEAVAGE_OF_CELLULAR_PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.4 REACTOME_ADENYLATE_CYCLASE_ACTIVATING_PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.4 REACTOME_PRESYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.4 REACTOME_TRANSLOCATION_OF_ZAP_70_TO_IMMUNOLOGICAL_SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 0.3 REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.3 REACTOME_FORMATION_OF_INCISION_COMPLEX_IN_GG_NER Genes involved in Formation of incision complex in GG-NER
0.0 0.2 REACTOME_NEGATIVE_REGULATION_OF_THE_PI3K_AKT_NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.2 REACTOME_DOPAMINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.0 0.1 REACTOME_SHC1_EVENTS_IN_EGFR_SIGNALING Genes involved in SHC1 events in EGFR signaling