Motif ID: JUND

Z-value: 0.701


Transcription factors associated with JUND:

Gene SymbolEntrez IDGene Name
JUND ENSG00000130522.4 JUND

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
JUNDhg19_v2_chr19_-_18391708_183917390.272.0e-01Click!


Activity profile for motif JUND.

activity profile for motif JUND


Sorted Z-values histogram for motif JUND

Sorted Z-values for motif JUND



Network of associatons between targets according to the STRING database.



First level regulatory network of JUND

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr11_-_102826434 1.640 ENST00000340273.4
ENST00000260302.3
MMP13

matrix metallopeptidase 13 (collagenase 3)

chr15_-_74504597 1.197 ENST00000416286.3
STRA6
stimulated by retinoic acid 6
chr5_-_140013275 1.185 ENST00000512545.1
ENST00000302014.6
ENST00000401743.2
CD14


CD14 molecule


chr15_-_74504560 1.145 ENST00000449139.2
STRA6
stimulated by retinoic acid 6
chrY_+_15016725 1.039 ENST00000336079.3
DDX3Y
DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
chr11_-_82708519 1.028 ENST00000534301.1
RAB30
RAB30, member RAS oncogene family
chr22_+_31488433 0.854 ENST00000455608.1
SMTN
smoothelin
chr1_-_153348067 0.815 ENST00000368737.3
S100A12
S100 calcium binding protein A12
chr12_-_95009837 0.727 ENST00000551457.1
TMCC3
transmembrane and coiled-coil domain family 3
chr22_-_37545972 0.713 ENST00000216223.5
IL2RB
interleukin 2 receptor, beta
chr3_-_169587621 0.712 ENST00000523069.1
ENST00000316428.5
ENST00000264676.5
LRRC31


leucine rich repeat containing 31


chr9_-_127263265 0.677 ENST00000373587.3
NR5A1
nuclear receptor subfamily 5, group A, member 1
chr7_+_79998864 0.658 ENST00000435819.1
CD36
CD36 molecule (thrombospondin receptor)
chr8_-_135522425 0.652 ENST00000521673.1
ZFAT
zinc finger and AT hook domain containing
chr3_-_48632593 0.590 ENST00000454817.1
ENST00000328333.8
COL7A1

collagen, type VII, alpha 1

chr15_+_89182178 0.581 ENST00000559876.1
ISG20
interferon stimulated exonuclease gene 20kDa
chr5_-_60140009 0.567 ENST00000505959.1
ELOVL7
ELOVL fatty acid elongase 7
chr5_-_60140089 0.562 ENST00000507047.1
ENST00000438340.1
ENST00000425382.1
ENST00000508821.1
ELOVL7



ELOVL fatty acid elongase 7



chr10_+_17270214 0.555 ENST00000544301.1
VIM
vimentin
chr4_-_104119528 0.529 ENST00000380026.3
ENST00000503705.1
ENST00000265148.3
CENPE


centromere protein E, 312kDa


chr15_+_89182156 0.481 ENST00000379224.5
ISG20
interferon stimulated exonuclease gene 20kDa
chr15_+_89181974 0.455 ENST00000306072.5
ISG20
interferon stimulated exonuclease gene 20kDa
chr6_-_32145861 0.424 ENST00000336984.6
AGPAT1
1-acylglycerol-3-phosphate O-acyltransferase 1
chr17_+_25799008 0.422 ENST00000583370.1
ENST00000398988.3
ENST00000268763.6
KSR1


kinase suppressor of ras 1


chr10_+_120116527 0.408 ENST00000445161.1
LINC00867
long intergenic non-protein coding RNA 867
chr12_-_95510743 0.392 ENST00000551521.1
FGD6
FYVE, RhoGEF and PH domain containing 6
chr20_-_62129163 0.382 ENST00000298049.7
EEF1A2
eukaryotic translation elongation factor 1 alpha 2
chrX_+_78200829 0.378 ENST00000544091.1
P2RY10
purinergic receptor P2Y, G-protein coupled, 10
chr8_-_27472198 0.359 ENST00000519472.1
ENST00000523589.1
ENST00000522413.1
ENST00000523396.1
ENST00000560366.1
CLU




clusterin




chr12_+_12938541 0.358 ENST00000356591.4
APOLD1
apolipoprotein L domain containing 1
chr2_+_169926047 0.351 ENST00000428522.1
ENST00000450153.1
ENST00000421653.1
DHRS9


dehydrogenase/reductase (SDR family) member 9


chr11_+_5617858 0.349 ENST00000380097.3
TRIM6
tripartite motif containing 6
chr9_-_39239171 0.331 ENST00000358144.2
CNTNAP3
contactin associated protein-like 3
chrX_+_99899180 0.326 ENST00000373004.3
SRPX2
sushi-repeat containing protein, X-linked 2
chr7_+_130126165 0.305 ENST00000427521.1
ENST00000416162.2
ENST00000378576.4
MEST


mesoderm specific transcript


chr5_-_141061777 0.303 ENST00000239440.4
ARAP3
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
chr19_+_13842559 0.303 ENST00000586600.1
CCDC130
coiled-coil domain containing 130
chr11_-_66103867 0.303 ENST00000424433.2
RIN1
Ras and Rab interactor 1
chr5_-_141061759 0.301 ENST00000508305.1
ARAP3
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
chr8_-_82359662 0.299 ENST00000519260.1
ENST00000256103.2
PMP2

peripheral myelin protein 2

chr6_-_44281043 0.284 ENST00000244571.4
AARS2
alanyl-tRNA synthetase 2, mitochondrial
chr19_-_54872556 0.277 ENST00000444687.1
LAIR1
leukocyte-associated immunoglobulin-like receptor 1
chr11_-_2162468 0.274 ENST00000434045.2
IGF2
insulin-like growth factor 2 (somatomedin A)
chr6_+_44194762 0.270 ENST00000371708.1
SLC29A1
solute carrier family 29 (equilibrative nucleoside transporter), member 1
chr19_+_11546093 0.269 ENST00000591462.1
PRKCSH
protein kinase C substrate 80K-H
chr12_+_62654155 0.268 ENST00000312635.6
ENST00000393654.3
ENST00000549237.1
USP15


ubiquitin specific peptidase 15


chr17_-_33390667 0.265 ENST00000378516.2
ENST00000268850.7
ENST00000394597.2
RFFL


ring finger and FYVE-like domain containing E3 ubiquitin protein ligase


chr17_-_28257080 0.264 ENST00000579954.1
ENST00000540801.1
ENST00000269033.3
ENST00000590153.1
ENST00000582084.1
SSH2




slingshot protein phosphatase 2




chr1_+_196912902 0.260 ENST00000476712.2
ENST00000367415.5
CFHR2

complement factor H-related 2

chr9_-_73029540 0.253 ENST00000377126.2
KLF9
Kruppel-like factor 9
chr12_-_8218997 0.245 ENST00000307637.4
C3AR1
complement component 3a receptor 1
chr12_+_54891495 0.243 ENST00000293373.6
NCKAP1L
NCK-associated protein 1-like
chr15_+_59903975 0.237 ENST00000560585.1
ENST00000396065.1
GCNT3

glucosaminyl (N-acetyl) transferase 3, mucin type

chr11_-_2162162 0.234 ENST00000381389.1
IGF2
insulin-like growth factor 2 (somatomedin A)
chr10_+_5005598 0.232 ENST00000442997.1
AKR1C1
aldo-keto reductase family 1, member C1
chr3_-_87325728 0.230 ENST00000350375.2
POU1F1
POU class 1 homeobox 1
chrX_+_99839799 0.225 ENST00000373031.4
TNMD
tenomodulin
chr21_-_43786634 0.224 ENST00000291527.2
TFF1
trefoil factor 1
chr2_-_187713891 0.213 ENST00000295131.2
ZSWIM2
zinc finger, SWIM-type containing 2
chr6_+_32146131 0.208 ENST00000375094.3
RNF5
ring finger protein 5, E3 ubiquitin protein ligase
chr16_+_15596123 0.206 ENST00000452191.2
C16orf45
chromosome 16 open reading frame 45
chr20_+_48429356 0.203 ENST00000361573.2
ENST00000541138.1
ENST00000539601.1
SLC9A8


solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8


chr21_+_42733870 0.202 ENST00000330714.3
ENST00000436410.1
ENST00000435611.1
MX2


myxovirus (influenza virus) resistance 2 (mouse)


chr11_-_4719072 0.199 ENST00000396950.3
ENST00000532598.1
OR51E2

olfactory receptor, family 51, subfamily E, member 2

chr20_+_48429233 0.197 ENST00000417961.1
SLC9A8
solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
chr13_+_109248500 0.188 ENST00000356711.2
MYO16
myosin XVI
chr11_-_14913190 0.179 ENST00000532378.1
CYP2R1
cytochrome P450, family 2, subfamily R, polypeptide 1
chr1_+_213224572 0.176 ENST00000543470.1
ENST00000366960.3
ENST00000366959.3
ENST00000543354.1
RPS6KC1



ribosomal protein S6 kinase, 52kDa, polypeptide 1



chr3_+_158991025 0.175 ENST00000337808.6
IQCJ-SCHIP1
IQCJ-SCHIP1 readthrough
chr3_-_157251383 0.173 ENST00000487753.1
ENST00000489602.1
ENST00000461299.1
ENST00000479987.1
VEPH1



ventricular zone expressed PH domain-containing 1



chr3_-_98241760 0.173 ENST00000507874.1
ENST00000502299.1
ENST00000508659.1
ENST00000510545.1
ENST00000511667.1
ENST00000394185.2
ENST00000394181.2
ENST00000508902.1
ENST00000341181.6
ENST00000437922.1
ENST00000394180.2
CLDND1










claudin domain containing 1










chr7_+_100663353 0.160 ENST00000306151.4
MUC17
mucin 17, cell surface associated
chr4_-_123377880 0.158 ENST00000226730.4
IL2
interleukin 2
chr11_+_67250490 0.156 ENST00000528641.2
ENST00000279146.3
AIP

aryl hydrocarbon receptor interacting protein

chr3_+_46412345 0.154 ENST00000292303.4
CCR5
chemokine (C-C motif) receptor 5 (gene/pseudogene)
chr3_-_105588231 0.149 ENST00000545639.1
ENST00000394027.3
ENST00000438603.1
ENST00000447441.1
ENST00000443752.1
CBLB




Cbl proto-oncogene B, E3 ubiquitin protein ligase




chr4_-_122085469 0.147 ENST00000057513.3
TNIP3
TNFAIP3 interacting protein 3
chr18_+_9885934 0.147 ENST00000357775.5
TXNDC2
thioredoxin domain containing 2 (spermatozoa)
chr5_-_138533973 0.142 ENST00000507002.1
ENST00000505830.1
ENST00000508639.1
ENST00000265195.5
SIL1



SIL1 nucleotide exchange factor



chr14_+_94492674 0.137 ENST00000203664.5
ENST00000553723.1
OTUB2

OTU domain, ubiquitin aldehyde binding 2

chr11_-_66103932 0.134 ENST00000311320.4
RIN1
Ras and Rab interactor 1
chr16_-_80603558 0.134 ENST00000567317.1
RP11-18F14.1
RP11-18F14.1
chr13_+_98605902 0.134 ENST00000460070.1
ENST00000481455.1
ENST00000261574.5
ENST00000493281.1
ENST00000463157.1
ENST00000471898.1
ENST00000489058.1
ENST00000481689.1
IPO5







importin 5







chr10_-_128210005 0.132 ENST00000284694.7
ENST00000454341.1
ENST00000432642.1
ENST00000392694.1
C10orf90



chromosome 10 open reading frame 90



chr18_+_55888767 0.130 ENST00000431212.2
ENST00000586268.1
ENST00000587190.1
NEDD4L


neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase


chr17_+_41052808 0.130 ENST00000592383.1
ENST00000253801.2
ENST00000585489.1
G6PC


glucose-6-phosphatase, catalytic subunit


chr10_-_14996321 0.130 ENST00000378289.4
DCLRE1C
DNA cross-link repair 1C
chr1_+_159796534 0.127 ENST00000289707.5
SLAMF8
SLAM family member 8
chr3_+_11178779 0.127 ENST00000438284.2
HRH1
histamine receptor H1
chr17_-_59668550 0.127 ENST00000521764.1
NACA2
nascent polypeptide-associated complex alpha subunit 2
chr11_-_66104237 0.127 ENST00000530056.1
RIN1
Ras and Rab interactor 1
chr15_-_51535208 0.125 ENST00000405913.3
ENST00000559878.1
CYP19A1

cytochrome P450, family 19, subfamily A, polypeptide 1

chr5_+_145317356 0.124 ENST00000511217.1
SH3RF2
SH3 domain containing ring finger 2
chr12_-_68553512 0.123 ENST00000229135.3
IFNG
interferon, gamma
chr22_+_22749343 0.121 ENST00000390298.2
IGLV7-43
immunoglobulin lambda variable 7-43
chr14_+_58765103 0.121 ENST00000355431.3
ENST00000348476.3
ENST00000395168.3
ARID4A


AT rich interactive domain 4A (RBP1-like)


chr12_+_62654119 0.117 ENST00000353364.3
ENST00000549523.1
ENST00000280377.5
USP15


ubiquitin specific peptidase 15


chr5_+_147582387 0.116 ENST00000325630.2
SPINK6
serine peptidase inhibitor, Kazal type 6
chr5_-_138534071 0.116 ENST00000394817.2
SIL1
SIL1 nucleotide exchange factor
chr4_+_95128996 0.113 ENST00000457823.2
SMARCAD1
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr1_+_117297007 0.111 ENST00000369478.3
ENST00000369477.1
CD2

CD2 molecule

chr15_+_42566384 0.111 ENST00000440615.2
ENST00000318010.8
GANC

glucosidase, alpha; neutral C

chr3_+_191046810 0.109 ENST00000392455.3
ENST00000392456.3
CCDC50

coiled-coil domain containing 50

chr16_+_31366536 0.099 ENST00000562522.1
ITGAX
integrin, alpha X (complement component 3 receptor 4 subunit)
chr10_-_74114714 0.098 ENST00000338820.3
ENST00000394903.2
ENST00000444643.2
DNAJB12


DnaJ (Hsp40) homolog, subfamily B, member 12


chr17_-_73150629 0.089 ENST00000356033.4
ENST00000405458.3
ENST00000409753.3
HN1


hematological and neurological expressed 1


chr12_-_53343602 0.086 ENST00000546897.1
ENST00000552551.1
KRT8

keratin 8

chr12_-_71182695 0.082 ENST00000342084.4
PTPRR
protein tyrosine phosphatase, receptor type, R
chr10_-_75008620 0.082 ENST00000372950.4
DNAJC9
DnaJ (Hsp40) homolog, subfamily C, member 9
chr2_+_161993465 0.079 ENST00000457476.1
TANK
TRAF family member-associated NFKB activator
chr10_+_17686124 0.078 ENST00000377524.3
STAM
signal transducing adaptor molecule (SH3 domain and ITAM motif) 1
chr20_+_30946106 0.077 ENST00000375687.4
ENST00000542461.1
ASXL1

additional sex combs like 1 (Drosophila)

chr17_-_7590745 0.072 ENST00000514944.1
ENST00000503591.1
ENST00000455263.2
ENST00000420246.2
ENST00000445888.2
ENST00000509690.1
ENST00000604348.1
ENST00000269305.4
TP53







tumor protein p53







chr11_-_5207612 0.069 ENST00000380367.1
OR52A1
olfactory receptor, family 52, subfamily A, member 1
chr18_+_32290218 0.069 ENST00000348997.5
ENST00000588949.1
ENST00000597599.1
DTNA


dystrobrevin, alpha


chr1_-_67266939 0.068 ENST00000304526.2
INSL5
insulin-like 5
chr6_+_150070857 0.068 ENST00000544496.1
PCMT1
protein-L-isoaspartate (D-aspartate) O-methyltransferase
chr1_-_153521597 0.059 ENST00000368712.1
S100A3
S100 calcium binding protein A3
chr18_-_19283649 0.059 ENST00000584464.1
ENST00000578270.1
ABHD3

abhydrolase domain containing 3

chr17_-_54893250 0.054 ENST00000397862.2
C17orf67
chromosome 17 open reading frame 67
chr10_-_81708854 0.053 ENST00000372292.3
SFTPD
surfactant protein D
chr2_+_161993412 0.053 ENST00000259075.2
ENST00000432002.1
TANK

TRAF family member-associated NFKB activator

chr13_-_31038370 0.051 ENST00000399489.1
ENST00000339872.4
HMGB1

high mobility group box 1

chr16_+_31366455 0.050 ENST00000268296.4
ITGAX
integrin, alpha X (complement component 3 receptor 4 subunit)
chr14_+_22977587 0.049 ENST00000390504.1
TRAJ33
T cell receptor alpha joining 33
chr3_+_127771212 0.046 ENST00000243253.3
ENST00000481210.1
SEC61A1

Sec61 alpha 1 subunit (S. cerevisiae)

chr16_+_28996364 0.046 ENST00000564277.1
LAT
linker for activation of T cells
chr2_+_102615416 0.045 ENST00000393414.2
IL1R2
interleukin 1 receptor, type II
chr5_-_135701164 0.044 ENST00000355180.3
ENST00000426057.2
ENST00000513104.1
TRPC7


transient receptor potential cation channel, subfamily C, member 7


chr6_+_159291090 0.044 ENST00000367073.4
ENST00000608817.1
C6orf99

chromosome 6 open reading frame 99

chr10_-_31288398 0.043 ENST00000538351.2
ZNF438
zinc finger protein 438
chr15_+_75335604 0.041 ENST00000563393.1
PPCDC
phosphopantothenoylcysteine decarboxylase
chr3_+_130150307 0.038 ENST00000512836.1
COL6A5
collagen, type VI, alpha 5
chr6_+_159290917 0.036 ENST00000367072.1
C6orf99
chromosome 6 open reading frame 99
chr18_-_74207146 0.032 ENST00000443185.2
ZNF516
zinc finger protein 516
chr15_+_38226827 0.032 ENST00000559502.1
ENST00000558148.1
ENST00000558158.1
TMCO5A


transmembrane and coiled-coil domains 5A


chrX_-_154493791 0.031 ENST00000369454.3
RAB39B
RAB39B, member RAS oncogene family
chr15_-_42565606 0.031 ENST00000307216.6
ENST00000448392.1
TMEM87A

transmembrane protein 87A

chr16_+_23847339 0.029 ENST00000303531.7
PRKCB
protein kinase C, beta
chr1_-_11918988 0.029 ENST00000376468.3
NPPB
natriuretic peptide B
chr17_+_1936687 0.028 ENST00000570477.1
DPH1
diphthamide biosynthesis 1
chr8_+_120220561 0.028 ENST00000276681.6
MAL2
mal, T-cell differentiation protein 2 (gene/pseudogene)
chr3_-_49395705 0.027 ENST00000419349.1
GPX1
glutathione peroxidase 1
chr10_-_50396425 0.027 ENST00000374148.1
C10orf128
chromosome 10 open reading frame 128
chr3_-_155011483 0.026 ENST00000489090.1
RP11-451G4.2
RP11-451G4.2
chr19_-_44008863 0.025 ENST00000601646.1
PHLDB3
pleckstrin homology-like domain, family B, member 3
chr3_-_170588163 0.025 ENST00000295830.8
RPL22L1
ribosomal protein L22-like 1
chr8_-_19102999 0.024 ENST00000517949.1
RP11-1080G15.1
RP11-1080G15.1
chr7_+_132937820 0.021 ENST00000393161.2
ENST00000253861.4
EXOC4

exocyst complex component 4

chrX_+_154254960 0.021 ENST00000369498.3
FUNDC2
FUN14 domain containing 2
chr3_-_18466026 0.019 ENST00000417717.2
SATB1
SATB homeobox 1
chr8_-_141774467 0.017 ENST00000520151.1
ENST00000519024.1
ENST00000519465.1
PTK2


protein tyrosine kinase 2


chr1_-_6662919 0.015 ENST00000377658.4
ENST00000377663.3
KLHL21

kelch-like family member 21

chrX_-_70326455 0.014 ENST00000374251.5
CXorf65
chromosome X open reading frame 65
chr6_-_43027105 0.013 ENST00000230413.5
ENST00000487429.1
ENST00000489623.1
ENST00000468957.1
MRPL2



mitochondrial ribosomal protein L2



chr6_+_149539767 0.011 ENST00000606202.1
ENST00000536230.1
ENST00000445901.1
TAB2

RP1-111D6.3
TGF-beta activated kinase 1/MAP3K7 binding protein 2

RP1-111D6.3
chr14_-_24711470 0.010 ENST00000559969.1
TINF2
TERF1 (TRF1)-interacting nuclear factor 2
chr19_+_35820064 0.010 ENST00000341773.6
ENST00000600131.1
ENST00000270311.6
ENST00000595780.1
ENST00000597916.1
ENST00000593867.1
ENST00000600424.1
ENST00000599811.1
ENST00000536635.2
ENST00000085219.5
ENST00000544992.2
ENST00000419549.2
CD22











CD22 molecule











chr11_+_59856130 0.009 ENST00000278888.3
MS4A2
membrane-spanning 4-domains, subfamily A, member 2
chr18_-_74839891 0.007 ENST00000581878.1
MBP
myelin basic protein
chr1_-_205744574 0.006 ENST00000367139.3
ENST00000235932.4
ENST00000437324.2
ENST00000414729.1
RAB7L1



RAB7, member RAS oncogene family-like 1



chr13_+_76378407 0.005 ENST00000447038.1
LMO7
LIM domain 7
chr1_+_41204506 0.002 ENST00000525290.1
ENST00000530965.1
ENST00000416859.2
ENST00000308733.5
NFYC



nuclear transcription factor Y, gamma



chr1_-_153513170 0.002 ENST00000368717.2
S100A5
S100 calcium binding protein A5

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.3 GO:0061143 alveolar primary septum development(GO:0061143)
0.3 1.5 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.3 1.2 GO:0038123 toll-like receptor TLR1:TLR2 signaling pathway(GO:0038123) response to triacyl bacterial lipopeptide(GO:0071725) cellular response to triacyl bacterial lipopeptide(GO:0071727)
0.2 0.7 GO:0007538 primary sex determination(GO:0007538)
0.1 1.1 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 0.7 GO:0038124 toll-like receptor TLR6:TLR2 signaling pathway(GO:0038124) response to diacyl bacterial lipopeptide(GO:0071724) cellular response to diacyl bacterial lipopeptide(GO:0071726)
0.1 0.7 GO:0038110 interleukin-2-mediated signaling pathway(GO:0038110)
0.1 0.4 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.1 0.3 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.1 0.5 GO:0007079 mitotic chromosome movement towards spindle pole(GO:0007079)
0.1 0.6 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.1 0.6 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.1 0.2 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.1 0.4 GO:1902998 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.1 0.2 GO:0060133 somatotropin secreting cell development(GO:0060133)
0.1 1.4 GO:0003417 growth plate cartilage development(GO:0003417)
0.1 0.5 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.1 0.2 GO:0035990 tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.1 0.3 GO:0015862 uridine transport(GO:0015862)
0.1 0.3 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.1 0.2 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.0 0.6 GO:0060020 Bergmann glial cell differentiation(GO:0060020)
0.0 0.2 GO:0036378 calcitriol biosynthetic process from calciol(GO:0036378)
0.0 0.1 GO:2000866 positive regulation of estrogen secretion(GO:2000863) positive regulation of estradiol secretion(GO:2000866)
0.0 0.2 GO:1903976 negative regulation of glial cell migration(GO:1903976)
0.0 0.1 GO:0032831 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302) regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032829) positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032831) positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559) positive regulation of tumor necrosis factor (ligand) superfamily member 11 production(GO:2000309)
0.0 0.3 GO:0051414 response to cortisol(GO:0051414)
0.0 0.2 GO:0009753 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.0 0.2 GO:1900133 regulation of renin secretion into blood stream(GO:1900133)
0.0 0.4 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0 0.3 GO:0002741 positive regulation of cytokine secretion involved in immune response(GO:0002741) regulation of ubiquitin homeostasis(GO:0010993) free ubiquitin chain polymerization(GO:0010994)
0.0 0.1 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.0 0.3 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.0 0.7 GO:0060712 spongiotrophoblast layer development(GO:0060712)
0.0 0.2 GO:0051342 regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342) negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.0 0.1 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.2 GO:0039663 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.0 0.1 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.0 0.1 GO:0097252 negative regulation of helicase activity(GO:0051097) positive regulation of thymocyte apoptotic process(GO:0070245) oligodendrocyte apoptotic process(GO:0097252)
0.0 0.4 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.1 GO:0000023 maltose metabolic process(GO:0000023)
0.0 0.1 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.0 0.4 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.0 0.4 GO:0042118 endothelial cell activation(GO:0042118)
0.0 0.4 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
0.0 0.1 GO:1902715 positive regulation of interferon-gamma secretion(GO:1902715)
0.0 0.2 GO:0003374 dynamin polymerization involved in membrane fission(GO:0003373) dynamin polymerization involved in mitochondrial fission(GO:0003374)
0.0 0.1 GO:0045085 negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.0 0.2 GO:0010759 positive regulation of macrophage chemotaxis(GO:0010759)
0.0 0.8 GO:0050832 defense response to fungus(GO:0050832)
0.0 0.3 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.0 1.0 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 0.1 GO:0032962 positive regulation of inositol trisphosphate biosynthetic process(GO:0032962)
0.0 0.1 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.0 0.1 GO:0032072 plasmacytoid dendritic cell activation(GO:0002270) T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840) regulation of restriction endodeoxyribonuclease activity(GO:0032072)
0.0 0.2 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.0 0.1 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 0.1 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.0 0.2 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.0 0.0 GO:0050712 negative regulation of interleukin-1 alpha production(GO:0032690) negative regulation of interleukin-1 alpha secretion(GO:0050712)
0.0 0.1 GO:1903551 regulation of extracellular exosome assembly(GO:1903551)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.2 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.1 0.6 GO:0030934 anchoring collagen complex(GO:0030934)
0.0 0.2 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 0.4 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.5 GO:0000940 condensed chromosome outer kinetochore(GO:0000940) mitotic spindle midzone(GO:1990023)
0.0 0.1 GO:0033565 ESCRT-0 complex(GO:0033565)
0.0 0.4 GO:0097418 neurofibrillary tangle(GO:0097418)
0.0 0.7 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.1 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.0 1.1 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.2 GO:0031209 SCAR complex(GO:0031209)
0.0 1.2 GO:0015030 Cajal body(GO:0015030)
0.0 0.2 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0008859 exoribonuclease II activity(GO:0008859)
0.2 1.2 GO:0016019 peptidoglycan receptor activity(GO:0016019)
0.2 0.7 GO:0004911 interleukin-2 receptor activity(GO:0004911) interleukin-2 binding(GO:0019976)
0.1 1.1 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 0.7 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.1 0.3 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.1 0.5 GO:0043515 kinetochore binding(GO:0043515)
0.1 0.6 GO:1990254 keratin filament binding(GO:1990254)
0.1 0.2 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.1 2.3 GO:0051183 vitamin transporter activity(GO:0051183)
0.1 0.2 GO:0047718 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006) androsterone dehydrogenase activity(GO:0047023) indanol dehydrogenase activity(GO:0047718)
0.1 0.4 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.0 0.2 GO:0070643 vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.0 0.4 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.0 0.9 GO:0050786 RAGE receptor binding(GO:0050786)
0.0 0.4 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.4 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.1 GO:0050309 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.0 0.2 GO:0030197 extracellular matrix constituent, lubricant activity(GO:0030197)
0.0 0.1 GO:0032450 maltose alpha-glucosidase activity(GO:0032450)
0.0 0.1 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.0 0.2 GO:0043208 glycosphingolipid binding(GO:0043208)
0.0 0.2 GO:0004875 complement receptor activity(GO:0004875)
0.0 0.6 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.4 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.4 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 0.2 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.4 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 1.4 GO:0005518 collagen binding(GO:0005518)
0.0 0.1 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 0.2 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.5 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.1 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.0 1.0 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004)
0.0 0.1 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.1 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.2 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.1 GO:0019871 sodium channel inhibitor activity(GO:0019871)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.2 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling
0.0 1.5 PID_UPA_UPAR_PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.9 PID_IL2_STAT5_PATHWAY IL2 signaling events mediated by STAT5
0.0 0.6 PID_RAS_PATHWAY Regulation of Ras family activation
0.0 0.6 NABA_COLLAGENS Genes encoding collagen proteins

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 REACTOME_IKK_COMPLEX_RECRUITMENT_MEDIATED_BY_RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 1.6 REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX Genes involved in Degradation of the extracellular matrix
0.0 1.1 REACTOME_SYNTHESIS_OF_VERY_LONG_CHAIN_FATTY_ACYL_COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 1.1 REACTOME_ADVANCED_GLYCOSYLATION_ENDPRODUCT_RECEPTOR_SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 0.2 REACTOME_BINDING_AND_ENTRY_OF_HIV_VIRION Genes involved in Binding and entry of HIV virion
0.0 0.5 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.9 REACTOME_IL_RECEPTOR_SHC_SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 1.7 REACTOME_INTERFERON_ALPHA_BETA_SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.6 REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.4 REACTOME_SYNTHESIS_OF_PA Genes involved in Synthesis of PA
0.0 0.1 REACTOME_REGULATION_OF_IFNG_SIGNALING Genes involved in Regulation of IFNG signaling