Motif ID: JUND

Z-value: 0.701


Transcription factors associated with JUND:

Gene SymbolEntrez IDGene Name
JUND ENSG00000130522.4 JUND

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
JUNDhg19_v2_chr19_-_18391708_183917390.272.0e-01Click!


Activity profile for motif JUND.

activity profile for motif JUND


Sorted Z-values histogram for motif JUND

Sorted Z-values for motif JUND



Network of associatons between targets according to the STRING database.



First level regulatory network of JUND

PNG image of the network

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Top targets:


Showing 1 to 20 of 164 entries
PromoterScoreRefseqGene SymbolGene Name
chr11_-_102826434 1.640 ENST00000340273.4
ENST00000260302.3
 MMP13

matrix metallopeptidase 13 (collagenase 3)

chr15_-_74504597 1.197 ENST00000416286.3
 STRA6
stimulated by retinoic acid 6
chr5_-_140013275 1.185 ENST00000512545.1
ENST00000302014.6
ENST00000401743.2
 CD14


CD14 molecule


chr15_-_74504560 1.145 ENST00000449139.2
 STRA6
stimulated by retinoic acid 6
chrY_+_15016725 1.039 ENST00000336079.3
 DDX3Y
DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
chr11_-_82708519 1.028 ENST00000534301.1
 RAB30
RAB30, member RAS oncogene family
chr22_+_31488433 0.854 ENST00000455608.1
 SMTN
smoothelin
chr1_-_153348067 0.815 ENST00000368737.3
 S100A12
S100 calcium binding protein A12
chr12_-_95009837 0.727 ENST00000551457.1
 TMCC3
transmembrane and coiled-coil domain family 3
chr22_-_37545972 0.713 ENST00000216223.5
 IL2RB
interleukin 2 receptor, beta
chr3_-_169587621 0.712 ENST00000523069.1
ENST00000316428.5
ENST00000264676.5
 LRRC31


leucine rich repeat containing 31


chr9_-_127263265 0.677 ENST00000373587.3
 NR5A1
nuclear receptor subfamily 5, group A, member 1
chr7_+_79998864 0.658 ENST00000435819.1
 CD36
CD36 molecule (thrombospondin receptor)
chr8_-_135522425 0.652 ENST00000521673.1
 ZFAT
zinc finger and AT hook domain containing
chr3_-_48632593 0.590 ENST00000454817.1
ENST00000328333.8
 COL7A1

collagen, type VII, alpha 1

chr15_+_89182178 0.581 ENST00000559876.1
 ISG20
interferon stimulated exonuclease gene 20kDa
chr5_-_60140009 0.567 ENST00000505959.1
 ELOVL7
ELOVL fatty acid elongase 7
chr5_-_60140089 0.562 ENST00000507047.1
ENST00000438340.1
ENST00000425382.1
ENST00000508821.1
 ELOVL7



ELOVL fatty acid elongase 7



chr10_+_17270214 0.555 ENST00000544301.1
 VIM
vimentin
chr4_-_104119528 0.529 ENST00000380026.3
ENST00000503705.1
ENST00000265148.3
 CENPE


centromere protein E, 312kDa



Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 61 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 2.3 GO:0061143 alveolar primary septum development(GO:0061143)
0.3 1.5 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.1 1.4 GO:0003417 growth plate cartilage development(GO:0003417)
0.3 1.2 GO:0038123 toll-like receptor TLR1:TLR2 signaling pathway(GO:0038123) response to triacyl bacterial lipopeptide(GO:0071725) cellular response to triacyl bacterial lipopeptide(GO:0071727)
0.1 1.1 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 1.0 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 0.8 GO:0050832 defense response to fungus(GO:0050832)
0.2 0.7 GO:0007538 primary sex determination(GO:0007538)
0.1 0.7 GO:0038124 toll-like receptor TLR6:TLR2 signaling pathway(GO:0038124) response to diacyl bacterial lipopeptide(GO:0071724) cellular response to diacyl bacterial lipopeptide(GO:0071726)
0.1 0.7 GO:0038110 interleukin-2-mediated signaling pathway(GO:0038110)
0.0 0.7 GO:0060712 spongiotrophoblast layer development(GO:0060712)
0.1 0.6 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.1 0.6 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 0.6 GO:0060020 Bergmann glial cell differentiation(GO:0060020)
0.1 0.5 GO:0007079 mitotic chromosome movement towards spindle pole(GO:0007079)
0.1 0.5 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.1 0.4 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.1 0.4 GO:1902998 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.0 0.4 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0 0.4 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)

Gene overrepresentation in cellular_component category:

Showing 1 to 13 of 13 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 1.2 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 1.2 GO:0015030 Cajal body(GO:0015030)
0.0 1.1 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.7 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.1 0.6 GO:0030934 anchoring collagen complex(GO:0030934)
0.0 0.5 GO:0000940 condensed chromosome outer kinetochore(GO:0000940) mitotic spindle midzone(GO:1990023)
0.0 0.4 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.4 GO:0097418 neurofibrillary tangle(GO:0097418)
0.0 0.2 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 0.2 GO:0031209 SCAR complex(GO:0031209)
0.0 0.2 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.0 0.1 GO:0033565 ESCRT-0 complex(GO:0033565)
0.0 0.1 GO:0005854 nascent polypeptide-associated complex(GO:0005854)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 38 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.3 GO:0051183 vitamin transporter activity(GO:0051183)
0.5 1.5 GO:0008859 exoribonuclease II activity(GO:0008859)
0.0 1.4 GO:0005518 collagen binding(GO:0005518)
0.2 1.2 GO:0016019 peptidoglycan receptor activity(GO:0016019)
0.1 1.1 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 1.0 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004)
0.0 0.9 GO:0050786 RAGE receptor binding(GO:0050786)
0.2 0.7 GO:0004911 interleukin-2 receptor activity(GO:0004911) interleukin-2 binding(GO:0019976)
0.1 0.7 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.1 0.6 GO:1990254 keratin filament binding(GO:1990254)
0.0 0.6 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.1 0.5 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.5 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.1 0.4 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.0 0.4 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.0 0.4 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.4 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.4 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.4 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 0.4 GO:0003746 translation elongation factor activity(GO:0003746)

Gene overrepresentation in C2:CP category:

Showing 1 to 5 of 5 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.5 PID_UPA_UPAR_PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 1.2 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling
0.0 0.9 PID_IL2_STAT5_PATHWAY IL2 signaling events mediated by STAT5
0.0 0.6 PID_RAS_PATHWAY Regulation of Ras family activation
0.0 0.6 NABA_COLLAGENS Genes encoding collagen proteins

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 11 of 11 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.7 REACTOME_INTERFERON_ALPHA_BETA_SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 1.6 REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX Genes involved in Degradation of the extracellular matrix
0.1 1.2 REACTOME_IKK_COMPLEX_RECRUITMENT_MEDIATED_BY_RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 1.1 REACTOME_SYNTHESIS_OF_VERY_LONG_CHAIN_FATTY_ACYL_COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 1.1 REACTOME_ADVANCED_GLYCOSYLATION_ENDPRODUCT_RECEPTOR_SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 0.9 REACTOME_IL_RECEPTOR_SHC_SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.6 REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.5 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.4 REACTOME_SYNTHESIS_OF_PA Genes involved in Synthesis of PA
0.0 0.2 REACTOME_BINDING_AND_ENTRY_OF_HIV_VIRION Genes involved in Binding and entry of HIV virion
0.0 0.1 REACTOME_REGULATION_OF_IFNG_SIGNALING Genes involved in Regulation of IFNG signaling