Motif ID: JUND
Z-value: 0.701
Transcription factors associated with JUND:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
JUND | ENSG00000130522.4 | JUND |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
JUND | hg19_v2_chr19_-_18391708_18391739 | 0.27 | 2.0e-01 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.5 | 2.3 | GO:0061143 | alveolar primary septum development(GO:0061143) |
0.3 | 1.5 | GO:0000738 | DNA catabolic process, exonucleolytic(GO:0000738) |
0.3 | 1.2 | GO:0038123 | toll-like receptor TLR1:TLR2 signaling pathway(GO:0038123) response to triacyl bacterial lipopeptide(GO:0071725) cellular response to triacyl bacterial lipopeptide(GO:0071727) |
0.2 | 0.7 | GO:0007538 | primary sex determination(GO:0007538) |
0.1 | 1.1 | GO:0019368 | fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626) |
0.1 | 0.7 | GO:0038124 | toll-like receptor TLR6:TLR2 signaling pathway(GO:0038124) response to diacyl bacterial lipopeptide(GO:0071724) cellular response to diacyl bacterial lipopeptide(GO:0071726) |
0.1 | 0.7 | GO:0038110 | interleukin-2-mediated signaling pathway(GO:0038110) |
0.1 | 0.4 | GO:0035616 | histone H2B conserved C-terminal lysine deubiquitination(GO:0035616) |
0.1 | 0.3 | GO:0006419 | alanyl-tRNA aminoacylation(GO:0006419) |
0.1 | 0.5 | GO:0007079 | mitotic chromosome movement towards spindle pole(GO:0007079) |
0.1 | 0.6 | GO:0035021 | negative regulation of Rac protein signal transduction(GO:0035021) |
0.1 | 0.6 | GO:0031914 | negative regulation of synaptic plasticity(GO:0031914) |
0.1 | 0.2 | GO:0043376 | regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376) |
0.1 | 0.4 | GO:1902998 | macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998) |
0.1 | 0.2 | GO:0060133 | somatotropin secreting cell development(GO:0060133) |
0.1 | 1.4 | GO:0003417 | growth plate cartilage development(GO:0003417) |
0.1 | 0.5 | GO:0038028 | insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028) |
0.1 | 0.2 | GO:0035990 | tendon cell differentiation(GO:0035990) tendon formation(GO:0035992) |
0.1 | 0.3 | GO:0015862 | uridine transport(GO:0015862) |
0.1 | 0.3 | GO:2001271 | negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271) |
0.1 | 0.2 | GO:0046013 | regulation of T cell homeostatic proliferation(GO:0046013) |
0.0 | 0.6 | GO:0060020 | Bergmann glial cell differentiation(GO:0060020) |
0.0 | 0.2 | GO:0036378 | calcitriol biosynthetic process from calciol(GO:0036378) |
0.0 | 0.1 | GO:2000866 | positive regulation of estrogen secretion(GO:2000863) positive regulation of estradiol secretion(GO:2000866) |
0.0 | 0.2 | GO:1903976 | negative regulation of glial cell migration(GO:1903976) |
0.0 | 0.1 | GO:0032831 | CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302) regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032829) positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032831) positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559) positive regulation of tumor necrosis factor (ligand) superfamily member 11 production(GO:2000309) |
0.0 | 0.3 | GO:0051414 | response to cortisol(GO:0051414) |
0.0 | 0.2 | GO:0009753 | response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395) |
0.0 | 0.2 | GO:1900133 | regulation of renin secretion into blood stream(GO:1900133) |
0.0 | 0.4 | GO:0042905 | 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905) |
0.0 | 0.3 | GO:0002741 | positive regulation of cytokine secretion involved in immune response(GO:0002741) regulation of ubiquitin homeostasis(GO:0010993) free ubiquitin chain polymerization(GO:0010994) |
0.0 | 0.1 | GO:0097368 | establishment of Sertoli cell barrier(GO:0097368) |
0.0 | 0.3 | GO:0090050 | positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050) |
0.0 | 0.7 | GO:0060712 | spongiotrophoblast layer development(GO:0060712) |
0.0 | 0.2 | GO:0051342 | regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342) negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344) |
0.0 | 0.1 | GO:2001288 | positive regulation of caveolin-mediated endocytosis(GO:2001288) |
0.0 | 0.2 | GO:0039663 | fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800) |
0.0 | 0.1 | GO:0035359 | negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359) |
0.0 | 0.1 | GO:0097252 | negative regulation of helicase activity(GO:0051097) positive regulation of thymocyte apoptotic process(GO:0070245) oligodendrocyte apoptotic process(GO:0097252) |
0.0 | 0.4 | GO:1990118 | sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118) |
0.0 | 0.1 | GO:0000023 | maltose metabolic process(GO:0000023) |
0.0 | 0.1 | GO:2000158 | positive regulation of ubiquitin-specific protease activity(GO:2000158) |
0.0 | 0.4 | GO:0016024 | CDP-diacylglycerol biosynthetic process(GO:0016024) |
0.0 | 0.4 | GO:0042118 | endothelial cell activation(GO:0042118) |
0.0 | 0.4 | GO:1904714 | regulation of chaperone-mediated autophagy(GO:1904714) |
0.0 | 0.1 | GO:1902715 | positive regulation of interferon-gamma secretion(GO:1902715) |
0.0 | 0.2 | GO:0003374 | dynamin polymerization involved in membrane fission(GO:0003373) dynamin polymerization involved in mitochondrial fission(GO:0003374) |
0.0 | 0.1 | GO:0045085 | negative regulation of interleukin-2 biosynthetic process(GO:0045085) |
0.0 | 0.2 | GO:0010759 | positive regulation of macrophage chemotaxis(GO:0010759) |
0.0 | 0.8 | GO:0050832 | defense response to fungus(GO:0050832) |
0.0 | 0.3 | GO:0045919 | positive regulation of cytolysis(GO:0045919) |
0.0 | 1.0 | GO:0010501 | RNA secondary structure unwinding(GO:0010501) |
0.0 | 0.1 | GO:0032962 | positive regulation of inositol trisphosphate biosynthetic process(GO:0032962) |
0.0 | 0.1 | GO:0035871 | protein K11-linked deubiquitination(GO:0035871) |
0.0 | 0.1 | GO:0032072 | plasmacytoid dendritic cell activation(GO:0002270) T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840) regulation of restriction endodeoxyribonuclease activity(GO:0032072) |
0.0 | 0.2 | GO:0071712 | ER-associated misfolded protein catabolic process(GO:0071712) |
0.0 | 0.1 | GO:0015712 | hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760) |
0.0 | 0.1 | GO:1903385 | regulation of homophilic cell adhesion(GO:1903385) |
0.0 | 0.2 | GO:0030277 | maintenance of gastrointestinal epithelium(GO:0030277) |
0.0 | 0.0 | GO:0050712 | negative regulation of interleukin-1 alpha production(GO:0032690) negative regulation of interleukin-1 alpha secretion(GO:0050712) |
0.0 | 0.1 | GO:1903551 | regulation of extracellular exosome assembly(GO:1903551) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 1.2 | GO:0046696 | lipopolysaccharide receptor complex(GO:0046696) |
0.1 | 0.6 | GO:0030934 | anchoring collagen complex(GO:0030934) |
0.0 | 0.2 | GO:0034751 | aryl hydrocarbon receptor complex(GO:0034751) |
0.0 | 0.4 | GO:0005853 | eukaryotic translation elongation factor 1 complex(GO:0005853) |
0.0 | 0.5 | GO:0000940 | condensed chromosome outer kinetochore(GO:0000940) mitotic spindle midzone(GO:1990023) |
0.0 | 0.1 | GO:0033565 | ESCRT-0 complex(GO:0033565) |
0.0 | 0.4 | GO:0097418 | neurofibrillary tangle(GO:0097418) |
0.0 | 0.7 | GO:0031092 | platelet alpha granule membrane(GO:0031092) |
0.0 | 0.1 | GO:0005854 | nascent polypeptide-associated complex(GO:0005854) |
0.0 | 1.1 | GO:0005801 | cis-Golgi network(GO:0005801) |
0.0 | 0.2 | GO:0031209 | SCAR complex(GO:0031209) |
0.0 | 1.2 | GO:0015030 | Cajal body(GO:0015030) |
0.0 | 0.2 | GO:0036513 | Derlin-1 retrotranslocation complex(GO:0036513) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.5 | 1.5 | GO:0008859 | exoribonuclease II activity(GO:0008859) |
0.2 | 1.2 | GO:0016019 | peptidoglycan receptor activity(GO:0016019) |
0.2 | 0.7 | GO:0004911 | interleukin-2 receptor activity(GO:0004911) interleukin-2 binding(GO:0019976) |
0.1 | 1.1 | GO:0009922 | fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338) |
0.1 | 0.7 | GO:0070892 | lipoteichoic acid receptor activity(GO:0070892) |
0.1 | 0.3 | GO:0004813 | alanine-tRNA ligase activity(GO:0004813) |
0.1 | 0.5 | GO:0043515 | kinetochore binding(GO:0043515) |
0.1 | 0.6 | GO:1990254 | keratin filament binding(GO:1990254) |
0.1 | 0.2 | GO:0003829 | beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829) |
0.1 | 2.3 | GO:0051183 | vitamin transporter activity(GO:0051183) |
0.1 | 0.2 | GO:0047718 | 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006) androsterone dehydrogenase activity(GO:0047023) indanol dehydrogenase activity(GO:0047718) |
0.1 | 0.4 | GO:0061649 | ubiquitinated histone binding(GO:0061649) |
0.0 | 0.2 | GO:0070643 | vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643) |
0.0 | 0.4 | GO:0047035 | testosterone dehydrogenase (NAD+) activity(GO:0047035) |
0.0 | 0.9 | GO:0050786 | RAGE receptor binding(GO:0050786) |
0.0 | 0.4 | GO:0005078 | MAP-kinase scaffold activity(GO:0005078) |
0.0 | 0.4 | GO:0015386 | potassium:proton antiporter activity(GO:0015386) |
0.0 | 0.1 | GO:0050309 | glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309) |
0.0 | 0.2 | GO:0030197 | extracellular matrix constituent, lubricant activity(GO:0030197) |
0.0 | 0.1 | GO:0032450 | maltose alpha-glucosidase activity(GO:0032450) |
0.0 | 0.1 | GO:0035800 | deubiquitinase activator activity(GO:0035800) |
0.0 | 0.2 | GO:0043208 | glycosphingolipid binding(GO:0043208) |
0.0 | 0.2 | GO:0004875 | complement receptor activity(GO:0004875) |
0.0 | 0.6 | GO:0043325 | phosphatidylinositol-3,4-bisphosphate binding(GO:0043325) |
0.0 | 0.4 | GO:0051787 | misfolded protein binding(GO:0051787) |
0.0 | 0.4 | GO:0003841 | 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) |
0.0 | 0.2 | GO:1904264 | ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264) |
0.0 | 0.4 | GO:0003746 | translation elongation factor activity(GO:0003746) |
0.0 | 1.4 | GO:0005518 | collagen binding(GO:0005518) |
0.0 | 0.1 | GO:0019784 | NEDD8-specific protease activity(GO:0019784) |
0.0 | 0.2 | GO:0019957 | C-C chemokine binding(GO:0019957) |
0.0 | 0.5 | GO:0005159 | insulin-like growth factor receptor binding(GO:0005159) |
0.0 | 0.1 | GO:0052740 | 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740) |
0.0 | 1.0 | GO:0004004 | ATP-dependent RNA helicase activity(GO:0004004) |
0.0 | 0.1 | GO:0004969 | histamine receptor activity(GO:0004969) |
0.0 | 0.1 | GO:0004719 | protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719) |
0.0 | 0.2 | GO:0017162 | aryl hydrocarbon receptor binding(GO:0017162) |
0.0 | 0.1 | GO:0019871 | sodium channel inhibitor activity(GO:0019871) |
Gene overrepresentation in C2:CP category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.0 | 1.2 | PID_TOLL_ENDOGENOUS_PATHWAY | Endogenous TLR signaling |
0.0 | 1.5 | PID_UPA_UPAR_PATHWAY | Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling |
0.0 | 0.9 | PID_IL2_STAT5_PATHWAY | IL2 signaling events mediated by STAT5 |
0.0 | 0.6 | PID_RAS_PATHWAY | Regulation of Ras family activation |
0.0 | 0.6 | NABA_COLLAGENS | Genes encoding collagen proteins |
Gene overrepresentation in C2:CP:REACTOME category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 1.2 | REACTOME_IKK_COMPLEX_RECRUITMENT_MEDIATED_BY_RIP1 | Genes involved in IKK complex recruitment mediated by RIP1 |
0.0 | 1.6 | REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX | Genes involved in Degradation of the extracellular matrix |
0.0 | 1.1 | REACTOME_SYNTHESIS_OF_VERY_LONG_CHAIN_FATTY_ACYL_COAS | Genes involved in Synthesis of very long-chain fatty acyl-CoAs |
0.0 | 1.1 | REACTOME_ADVANCED_GLYCOSYLATION_ENDPRODUCT_RECEPTOR_SIGNALING | Genes involved in Advanced glycosylation endproduct receptor signaling |
0.0 | 0.2 | REACTOME_BINDING_AND_ENTRY_OF_HIV_VIRION | Genes involved in Binding and entry of HIV virion |
0.0 | 0.5 | REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS | Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs) |
0.0 | 0.9 | REACTOME_IL_RECEPTOR_SHC_SIGNALING | Genes involved in Interleukin receptor SHC signaling |
0.0 | 1.7 | REACTOME_INTERFERON_ALPHA_BETA_SIGNALING | Genes involved in Interferon alpha/beta signaling |
0.0 | 0.6 | REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS | Genes involved in Caspase-mediated cleavage of cytoskeletal proteins |
0.0 | 0.4 | REACTOME_SYNTHESIS_OF_PA | Genes involved in Synthesis of PA |
0.0 | 0.1 | REACTOME_REGULATION_OF_IFNG_SIGNALING | Genes involved in Regulation of IFNG signaling |