Motif ID: KLF1
Z-value: 1.321
Transcription factors associated with KLF1:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| KLF1 | ENSG00000105610.4 | KLF1 |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| KLF1 | hg19_v2_chr19_-_12997995_12998021 | -0.19 | 3.8e-01 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.9 | 9.7 | GO:0002317 | plasma cell differentiation(GO:0002317) |
| 1.2 | 9.9 | GO:0006452 | translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905) |
| 0.8 | 2.4 | GO:0048627 | myoblast development(GO:0048627) |
| 0.8 | 2.4 | GO:0000412 | histone peptidyl-prolyl isomerization(GO:0000412) |
| 0.8 | 2.3 | GO:0006535 | cysteine biosynthetic process from serine(GO:0006535) |
| 0.8 | 3.9 | GO:0099590 | neurotransmitter receptor internalization(GO:0099590) |
| 0.8 | 2.3 | GO:2000646 | positive regulation of receptor catabolic process(GO:2000646) |
| 0.6 | 2.8 | GO:0033078 | extrathymic T cell differentiation(GO:0033078) |
| 0.5 | 3.0 | GO:0072675 | multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675) |
| 0.5 | 2.5 | GO:0033274 | response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829) |
| 0.4 | 2.6 | GO:1900748 | positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748) |
| 0.4 | 3.8 | GO:0030579 | ubiquitin-dependent SMAD protein catabolic process(GO:0030579) |
| 0.4 | 1.9 | GO:0010760 | negative regulation of macrophage chemotaxis(GO:0010760) |
| 0.4 | 1.1 | GO:0090149 | mitochondrial membrane fission(GO:0090149) |
| 0.4 | 2.2 | GO:1902766 | skeletal muscle satellite cell migration(GO:1902766) |
| 0.4 | 1.1 | GO:1903926 | signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926) |
| 0.4 | 2.2 | GO:0016479 | negative regulation of transcription from RNA polymerase I promoter(GO:0016479) |
| 0.4 | 2.1 | GO:1903575 | cornified envelope assembly(GO:1903575) |
| 0.4 | 3.2 | GO:0086073 | bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073) |
| 0.3 | 1.4 | GO:1902044 | regulation of Fas signaling pathway(GO:1902044) |
| 0.3 | 4.2 | GO:0060020 | Bergmann glial cell differentiation(GO:0060020) |
| 0.3 | 1.4 | GO:0090038 | negative regulation of protein kinase C signaling(GO:0090038) |
| 0.3 | 1.7 | GO:0097021 | Peyer's patch morphogenesis(GO:0061146) lymphocyte migration into lymphoid organs(GO:0097021) |
| 0.3 | 1.4 | GO:1903285 | negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470) |
| 0.3 | 0.8 | GO:2000687 | negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687) |
| 0.3 | 1.3 | GO:0006436 | tryptophanyl-tRNA aminoacylation(GO:0006436) |
| 0.3 | 7.6 | GO:0031581 | hemidesmosome assembly(GO:0031581) |
| 0.3 | 2.1 | GO:2000543 | positive regulation of gastrulation(GO:2000543) |
| 0.3 | 2.5 | GO:1900004 | negative regulation of serine-type endopeptidase activity(GO:1900004) negative regulation of serine-type peptidase activity(GO:1902572) |
| 0.2 | 3.4 | GO:2000675 | negative regulation of type B pancreatic cell apoptotic process(GO:2000675) |
| 0.2 | 0.7 | GO:1902869 | commitment of multipotent stem cells to neuronal lineage in forebrain(GO:0021898) regulation of amacrine cell differentiation(GO:1902869) |
| 0.2 | 1.2 | GO:0046340 | diacylglycerol catabolic process(GO:0046340) |
| 0.2 | 0.5 | GO:0002159 | desmosome assembly(GO:0002159) |
| 0.2 | 1.8 | GO:1903764 | regulation of potassium ion export across plasma membrane(GO:1903764) |
| 0.2 | 2.3 | GO:0007217 | tachykinin receptor signaling pathway(GO:0007217) |
| 0.2 | 1.4 | GO:0051012 | microtubule sliding(GO:0051012) |
| 0.2 | 0.9 | GO:0021592 | fourth ventricle development(GO:0021592) |
| 0.2 | 0.9 | GO:0071393 | cellular response to progesterone stimulus(GO:0071393) |
| 0.2 | 2.3 | GO:0035634 | response to stilbenoid(GO:0035634) |
| 0.2 | 0.6 | GO:0098937 | dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937) |
| 0.2 | 0.8 | GO:0097010 | eukaryotic translation initiation factor 4F complex assembly(GO:0097010) |
| 0.2 | 1.0 | GO:0018125 | peptidyl-cysteine methylation(GO:0018125) |
| 0.2 | 2.9 | GO:0090168 | Golgi reassembly(GO:0090168) |
| 0.2 | 1.5 | GO:0010724 | regulation of definitive erythrocyte differentiation(GO:0010724) |
| 0.2 | 2.8 | GO:1904778 | regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778) |
| 0.2 | 2.0 | GO:0015824 | proline transport(GO:0015824) |
| 0.2 | 5.0 | GO:0035855 | megakaryocyte development(GO:0035855) |
| 0.2 | 1.1 | GO:0032185 | septin cytoskeleton organization(GO:0032185) |
| 0.2 | 0.7 | GO:0060392 | negative regulation of SMAD protein import into nucleus(GO:0060392) |
| 0.2 | 1.4 | GO:0036486 | trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486) |
| 0.2 | 0.7 | GO:1990502 | dense core granule maturation(GO:1990502) |
| 0.2 | 0.5 | GO:0002281 | macrophage activation involved in immune response(GO:0002281) |
| 0.2 | 4.9 | GO:0060216 | definitive hemopoiesis(GO:0060216) |
| 0.1 | 2.6 | GO:0030388 | fructose 1,6-bisphosphate metabolic process(GO:0030388) |
| 0.1 | 0.4 | GO:0051885 | positive regulation of anagen(GO:0051885) |
| 0.1 | 18.3 | GO:0070268 | cornification(GO:0070268) |
| 0.1 | 0.4 | GO:0001560 | regulation of cell growth by extracellular stimulus(GO:0001560) |
| 0.1 | 0.8 | GO:2000324 | positive regulation of glucocorticoid receptor signaling pathway(GO:2000324) |
| 0.1 | 0.5 | GO:0090258 | negative regulation of mitochondrial fission(GO:0090258) |
| 0.1 | 0.4 | GO:1903181 | regulation of dopamine biosynthetic process(GO:1903179) positive regulation of dopamine biosynthetic process(GO:1903181) negative regulation of protein catabolic process in the vacuole(GO:1904351) negative regulation of lysosomal protein catabolic process(GO:1905166) |
| 0.1 | 0.9 | GO:2000782 | regulation of unidimensional cell growth(GO:0051510) negative regulation of unidimensional cell growth(GO:0051511) establishment of cell polarity regulating cell shape(GO:0071964) regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000769) positive regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000771) regulation of establishment of cell polarity regulating cell shape(GO:2000782) positive regulation of establishment of cell polarity regulating cell shape(GO:2000784) positive regulation of barbed-end actin filament capping(GO:2000814) |
| 0.1 | 0.9 | GO:0035507 | regulation of myosin-light-chain-phosphatase activity(GO:0035507) |
| 0.1 | 0.9 | GO:0010989 | negative regulation of low-density lipoprotein particle clearance(GO:0010989) |
| 0.1 | 1.9 | GO:0007196 | adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196) |
| 0.1 | 1.0 | GO:0002175 | protein localization to paranode region of axon(GO:0002175) |
| 0.1 | 1.4 | GO:0032808 | lacrimal gland development(GO:0032808) |
| 0.1 | 0.6 | GO:0050916 | sensory perception of sweet taste(GO:0050916) sensory perception of umami taste(GO:0050917) |
| 0.1 | 0.4 | GO:0060988 | lipid tube assembly(GO:0060988) |
| 0.1 | 2.0 | GO:0071803 | positive regulation of podosome assembly(GO:0071803) |
| 0.1 | 0.8 | GO:0071926 | endocannabinoid signaling pathway(GO:0071926) regulation of endocannabinoid signaling pathway(GO:2000124) |
| 0.1 | 0.4 | GO:1905224 | clathrin-coated pit assembly(GO:1905224) |
| 0.1 | 0.4 | GO:1903377 | negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377) |
| 0.1 | 0.5 | GO:1900168 | glial cell-derived neurotrophic factor secretion(GO:0044467) positive regulation of neurotransmitter uptake(GO:0051582) positive regulation of dopamine uptake involved in synaptic transmission(GO:0051586) positive regulation of catecholamine uptake involved in synaptic transmission(GO:0051944) regulation of glial cell-derived neurotrophic factor secretion(GO:1900166) positive regulation of glial cell-derived neurotrophic factor secretion(GO:1900168) |
| 0.1 | 0.5 | GO:0042247 | morphogenesis of follicular epithelium(GO:0016333) establishment or maintenance of polarity of follicular epithelium(GO:0016334) establishment of planar polarity of follicular epithelium(GO:0042247) |
| 0.1 | 0.8 | GO:0007197 | adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) |
| 0.1 | 0.5 | GO:2001288 | T-tubule organization(GO:0033292) regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373) positive regulation of caveolin-mediated endocytosis(GO:2001288) |
| 0.1 | 1.0 | GO:0010993 | regulation of ubiquitin homeostasis(GO:0010993) free ubiquitin chain polymerization(GO:0010994) |
| 0.1 | 0.9 | GO:0019368 | fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626) |
| 0.1 | 2.4 | GO:0000185 | activation of MAPKKK activity(GO:0000185) |
| 0.1 | 0.4 | GO:0060265 | positive regulation of respiratory burst involved in inflammatory response(GO:0060265) |
| 0.1 | 0.4 | GO:0003415 | chondrocyte hypertrophy(GO:0003415) |
| 0.1 | 2.3 | GO:0033622 | integrin activation(GO:0033622) |
| 0.1 | 1.7 | GO:0015812 | gamma-aminobutyric acid transport(GO:0015812) |
| 0.1 | 1.1 | GO:1900086 | positive regulation of peptidyl-tyrosine autophosphorylation(GO:1900086) |
| 0.1 | 0.8 | GO:0060052 | neurofilament cytoskeleton organization(GO:0060052) |
| 0.1 | 0.6 | GO:0008626 | granzyme-mediated apoptotic signaling pathway(GO:0008626) |
| 0.1 | 0.4 | GO:0010482 | epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482) |
| 0.1 | 1.3 | GO:0019388 | galactose catabolic process(GO:0019388) |
| 0.1 | 0.3 | GO:0018242 | protein O-linked glycosylation via serine(GO:0018242) |
| 0.1 | 0.4 | GO:1900242 | regulation of synaptic vesicle endocytosis(GO:1900242) |
| 0.1 | 0.5 | GO:0008063 | Toll signaling pathway(GO:0008063) |
| 0.1 | 0.4 | GO:0070682 | proteasome regulatory particle assembly(GO:0070682) |
| 0.1 | 0.5 | GO:1902031 | regulation of NADP metabolic process(GO:1902031) |
| 0.1 | 3.5 | GO:1901385 | regulation of voltage-gated calcium channel activity(GO:1901385) |
| 0.1 | 0.4 | GO:0006177 | GMP biosynthetic process(GO:0006177) |
| 0.1 | 0.3 | GO:0098528 | skeletal muscle fiber differentiation(GO:0098528) |
| 0.1 | 1.9 | GO:0045332 | phospholipid translocation(GO:0045332) |
| 0.1 | 0.3 | GO:1904637 | response to ionomycin(GO:1904636) cellular response to ionomycin(GO:1904637) |
| 0.1 | 0.3 | GO:0031117 | positive regulation of microtubule depolymerization(GO:0031117) |
| 0.1 | 1.3 | GO:0044342 | type B pancreatic cell proliferation(GO:0044342) |
| 0.1 | 0.4 | GO:0006287 | base-excision repair, gap-filling(GO:0006287) |
| 0.1 | 1.0 | GO:0015693 | magnesium ion transport(GO:0015693) |
| 0.1 | 1.1 | GO:0006474 | N-terminal protein amino acid acetylation(GO:0006474) |
| 0.1 | 0.2 | GO:0032679 | TRAIL production(GO:0032639) regulation of TRAIL production(GO:0032679) positive regulation of TRAIL production(GO:0032759) |
| 0.1 | 0.6 | GO:0071787 | endoplasmic reticulum tubular network assembly(GO:0071787) |
| 0.1 | 3.1 | GO:0035735 | intraciliary transport involved in cilium morphogenesis(GO:0035735) |
| 0.1 | 0.4 | GO:2001256 | regulation of store-operated calcium entry(GO:2001256) |
| 0.1 | 0.2 | GO:0048597 | B cell negative selection(GO:0002352) post-embryonic camera-type eye morphogenesis(GO:0048597) |
| 0.1 | 1.0 | GO:0060707 | trophoblast giant cell differentiation(GO:0060707) |
| 0.1 | 0.2 | GO:1903225 | negative regulation of endodermal cell differentiation(GO:1903225) |
| 0.1 | 0.3 | GO:0030070 | insulin processing(GO:0030070) |
| 0.1 | 0.5 | GO:0000160 | phosphorelay signal transduction system(GO:0000160) |
| 0.1 | 0.6 | GO:0030091 | protein repair(GO:0030091) |
| 0.0 | 0.2 | GO:0035672 | oligopeptide transmembrane transport(GO:0035672) |
| 0.0 | 1.7 | GO:0022400 | regulation of rhodopsin mediated signaling pathway(GO:0022400) |
| 0.0 | 0.5 | GO:0021894 | cerebral cortex GABAergic interneuron development(GO:0021894) |
| 0.0 | 0.0 | GO:0048146 | positive regulation of fibroblast proliferation(GO:0048146) |
| 0.0 | 0.2 | GO:1900194 | negative regulation of oocyte maturation(GO:1900194) |
| 0.0 | 2.2 | GO:1903959 | regulation of anion transmembrane transport(GO:1903959) |
| 0.0 | 0.2 | GO:0006402 | mRNA catabolic process(GO:0006402) |
| 0.0 | 0.8 | GO:0060575 | intestinal epithelial cell differentiation(GO:0060575) |
| 0.0 | 0.5 | GO:0043249 | erythrocyte maturation(GO:0043249) |
| 0.0 | 2.8 | GO:0046580 | negative regulation of Ras protein signal transduction(GO:0046580) |
| 0.0 | 0.9 | GO:0002089 | lens morphogenesis in camera-type eye(GO:0002089) |
| 0.0 | 0.1 | GO:0010701 | positive regulation of norepinephrine secretion(GO:0010701) |
| 0.0 | 0.2 | GO:2000370 | positive regulation of clathrin-mediated endocytosis(GO:2000370) |
| 0.0 | 2.8 | GO:0030049 | muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275) |
| 0.0 | 0.3 | GO:0097116 | gephyrin clustering involved in postsynaptic density assembly(GO:0097116) |
| 0.0 | 0.5 | GO:0015074 | DNA integration(GO:0015074) |
| 0.0 | 0.1 | GO:0070093 | negative regulation of glucagon secretion(GO:0070093) |
| 0.0 | 0.8 | GO:0021904 | dorsal/ventral neural tube patterning(GO:0021904) |
| 0.0 | 0.7 | GO:0043508 | negative regulation of JUN kinase activity(GO:0043508) |
| 0.0 | 0.1 | GO:0016476 | regulation of embryonic cell shape(GO:0016476) |
| 0.0 | 1.2 | GO:0006359 | regulation of transcription from RNA polymerase III promoter(GO:0006359) |
| 0.0 | 0.6 | GO:0007567 | parturition(GO:0007567) |
| 0.0 | 0.6 | GO:0034380 | high-density lipoprotein particle assembly(GO:0034380) |
| 0.0 | 1.0 | GO:0030252 | growth hormone secretion(GO:0030252) |
| 0.0 | 0.6 | GO:0001973 | adenosine receptor signaling pathway(GO:0001973) |
| 0.0 | 0.1 | GO:0072553 | terminal button organization(GO:0072553) |
| 0.0 | 0.4 | GO:0032802 | low-density lipoprotein particle receptor catabolic process(GO:0032802) |
| 0.0 | 0.9 | GO:0035774 | positive regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0035774) |
| 0.0 | 0.2 | GO:0061737 | leukotriene signaling pathway(GO:0061737) |
| 0.0 | 0.2 | GO:0034770 | histone H4-K20 methylation(GO:0034770) |
| 0.0 | 0.3 | GO:0070212 | protein poly-ADP-ribosylation(GO:0070212) |
| 0.0 | 0.4 | GO:1903779 | regulation of cardiac conduction(GO:1903779) |
| 0.0 | 1.1 | GO:0030206 | chondroitin sulfate biosynthetic process(GO:0030206) |
| 0.0 | 0.1 | GO:0051005 | negative regulation of lipoprotein lipase activity(GO:0051005) |
| 0.0 | 1.2 | GO:0051782 | negative regulation of cell division(GO:0051782) |
| 0.0 | 0.1 | GO:0072254 | metanephric mesangial cell differentiation(GO:0072209) metanephric glomerular mesangial cell differentiation(GO:0072254) metanephric glomerular mesangial cell development(GO:0072255) reversible differentiation(GO:0090677) cell dedifferentiation involved in phenotypic switching(GO:0090678) positive regulation of phenotypic switching(GO:1900241) regulation of vascular smooth muscle cell dedifferentiation(GO:1905174) positive regulation of vascular smooth muscle cell dedifferentiation(GO:1905176) vascular smooth muscle cell dedifferentiation(GO:1990936) |
| 0.0 | 0.4 | GO:0071108 | protein K48-linked deubiquitination(GO:0071108) |
| 0.0 | 0.3 | GO:0048266 | behavioral response to pain(GO:0048266) |
| 0.0 | 0.1 | GO:0042797 | tRNA transcription(GO:0009304) 5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797) |
| 0.0 | 0.8 | GO:0015695 | organic cation transport(GO:0015695) |
| 0.0 | 0.1 | GO:0098707 | ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707) |
| 0.0 | 0.1 | GO:0043587 | tongue morphogenesis(GO:0043587) |
| 0.0 | 0.6 | GO:0051290 | protein heterotetramerization(GO:0051290) |
| 0.0 | 0.3 | GO:0031573 | intra-S DNA damage checkpoint(GO:0031573) |
| 0.0 | 1.1 | GO:0015914 | phospholipid transport(GO:0015914) |
| 0.0 | 0.3 | GO:0032688 | negative regulation of interferon-beta production(GO:0032688) |
| 0.0 | 0.3 | GO:0090385 | phagosome-lysosome fusion(GO:0090385) |
| 0.0 | 0.0 | GO:1901491 | negative regulation of lymphangiogenesis(GO:1901491) |
| 0.0 | 0.6 | GO:0022038 | corpus callosum development(GO:0022038) |
| 0.0 | 0.6 | GO:0072600 | establishment of protein localization to Golgi(GO:0072600) |
| 0.0 | 0.4 | GO:0006490 | oligosaccharide-lipid intermediate biosynthetic process(GO:0006490) |
| 0.0 | 0.4 | GO:0000717 | nucleotide-excision repair, DNA duplex unwinding(GO:0000717) |
| 0.0 | 0.4 | GO:0007095 | mitotic G2 DNA damage checkpoint(GO:0007095) |
| 0.0 | 3.5 | GO:0042177 | negative regulation of protein catabolic process(GO:0042177) |
| 0.0 | 0.4 | GO:0045599 | negative regulation of fat cell differentiation(GO:0045599) |
| 0.0 | 0.7 | GO:0007249 | I-kappaB kinase/NF-kappaB signaling(GO:0007249) |
| 0.0 | 2.3 | GO:0006939 | smooth muscle contraction(GO:0006939) |
| 0.0 | 0.3 | GO:0006995 | cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562) |
| 0.0 | 1.2 | GO:0050819 | negative regulation of coagulation(GO:0050819) |
| 0.0 | 0.2 | GO:0030046 | parallel actin filament bundle assembly(GO:0030046) |
| 0.0 | 0.1 | GO:0035105 | sterol regulatory element binding protein import into nucleus(GO:0035105) |
| 0.0 | 0.2 | GO:1904896 | ESCRT complex disassembly(GO:1904896) ESCRT III complex disassembly(GO:1904903) |
| 0.0 | 0.4 | GO:0071371 | cellular response to gonadotropin stimulus(GO:0071371) |
| 0.0 | 0.3 | GO:0002028 | regulation of sodium ion transport(GO:0002028) |
| 0.0 | 0.9 | GO:0030212 | hyaluronan metabolic process(GO:0030212) |
| 0.0 | 0.5 | GO:0007190 | activation of adenylate cyclase activity(GO:0007190) |
| 0.0 | 0.1 | GO:0030513 | positive regulation of BMP signaling pathway(GO:0030513) |
| 0.0 | 0.2 | GO:0021794 | thalamus development(GO:0021794) |
| 0.0 | 0.1 | GO:0007288 | sperm axoneme assembly(GO:0007288) |
| 0.0 | 0.2 | GO:0031937 | positive regulation of chromatin silencing(GO:0031937) |
| 0.0 | 0.1 | GO:0032836 | glomerular basement membrane development(GO:0032836) |
| 0.0 | 0.2 | GO:0060155 | platelet dense granule organization(GO:0060155) |
| 0.0 | 0.8 | GO:0021762 | substantia nigra development(GO:0021762) |
| 0.0 | 0.4 | GO:0032463 | negative regulation of protein homooligomerization(GO:0032463) |
| 0.0 | 0.3 | GO:0000028 | ribosomal small subunit assembly(GO:0000028) |
| 0.0 | 1.1 | GO:0008284 | positive regulation of cell proliferation(GO:0008284) |
| 0.0 | 0.9 | GO:0030574 | collagen catabolic process(GO:0030574) |
| 0.0 | 0.2 | GO:0015937 | coenzyme A biosynthetic process(GO:0015937) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.0 | 2.9 | GO:0034676 | integrin alpha6-beta4 complex(GO:0034676) |
| 0.8 | 9.9 | GO:0005642 | annulate lamellae(GO:0005642) |
| 0.8 | 2.3 | GO:1990666 | PCSK9-LDLR complex(GO:1990666) |
| 0.7 | 2.2 | GO:0031523 | Myb complex(GO:0031523) |
| 0.7 | 2.6 | GO:0045160 | myosin I complex(GO:0045160) |
| 0.4 | 3.1 | GO:0005610 | laminin-5 complex(GO:0005610) |
| 0.3 | 4.3 | GO:0031209 | SCAR complex(GO:0031209) |
| 0.3 | 9.6 | GO:0030057 | desmosome(GO:0030057) |
| 0.3 | 1.0 | GO:0034991 | nuclear meiotic cohesin complex(GO:0034991) |
| 0.2 | 4.3 | GO:0036020 | endolysosome membrane(GO:0036020) |
| 0.2 | 0.9 | GO:0030934 | anchoring collagen complex(GO:0030934) |
| 0.2 | 5.6 | GO:0043205 | microfibril(GO:0001527) fibril(GO:0043205) |
| 0.2 | 0.9 | GO:0097513 | myosin II filament(GO:0097513) |
| 0.2 | 5.9 | GO:0031092 | platelet alpha granule membrane(GO:0031092) |
| 0.2 | 1.0 | GO:0070381 | endosome to plasma membrane transport vesicle(GO:0070381) |
| 0.2 | 2.5 | GO:0008091 | spectrin(GO:0008091) |
| 0.2 | 1.8 | GO:0043219 | lateral loop(GO:0043219) |
| 0.1 | 0.1 | GO:0016533 | cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533) |
| 0.1 | 2.0 | GO:0090543 | Flemming body(GO:0090543) |
| 0.1 | 2.0 | GO:0030478 | actin cap(GO:0030478) |
| 0.1 | 0.6 | GO:0030906 | retromer, cargo-selective complex(GO:0030906) |
| 0.1 | 1.1 | GO:0036056 | filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057) |
| 0.1 | 2.8 | GO:0031235 | intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235) |
| 0.1 | 0.8 | GO:1990635 | proximal dendrite(GO:1990635) |
| 0.1 | 5.8 | GO:0043034 | costamere(GO:0043034) |
| 0.1 | 0.9 | GO:0031415 | NatA complex(GO:0031415) |
| 0.1 | 0.3 | GO:0036195 | muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195) |
| 0.1 | 1.0 | GO:0072357 | PTW/PP1 phosphatase complex(GO:0072357) |
| 0.1 | 15.6 | GO:0005882 | intermediate filament(GO:0005882) |
| 0.1 | 1.7 | GO:0042622 | photoreceptor outer segment membrane(GO:0042622) |
| 0.1 | 0.5 | GO:0042643 | actomyosin, actin portion(GO:0042643) |
| 0.1 | 0.5 | GO:0071817 | MMXD complex(GO:0071817) |
| 0.1 | 1.5 | GO:0005862 | muscle thin filament tropomyosin(GO:0005862) |
| 0.1 | 0.5 | GO:0045298 | tubulin complex(GO:0045298) |
| 0.1 | 1.7 | GO:0005861 | troponin complex(GO:0005861) |
| 0.1 | 1.0 | GO:0033270 | paranode region of axon(GO:0033270) |
| 0.1 | 0.2 | GO:0031417 | NatC complex(GO:0031417) |
| 0.1 | 0.2 | GO:0005588 | collagen type V trimer(GO:0005588) |
| 0.0 | 1.2 | GO:0005666 | DNA-directed RNA polymerase III complex(GO:0005666) |
| 0.0 | 2.5 | GO:0031430 | M band(GO:0031430) |
| 0.0 | 0.3 | GO:0097129 | cyclin D2-CDK4 complex(GO:0097129) |
| 0.0 | 0.6 | GO:0032433 | filopodium tip(GO:0032433) |
| 0.0 | 0.6 | GO:0035253 | ciliary rootlet(GO:0035253) |
| 0.0 | 0.3 | GO:0030896 | checkpoint clamp complex(GO:0030896) |
| 0.0 | 0.5 | GO:0005664 | origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664) |
| 0.0 | 0.8 | GO:0016281 | eukaryotic translation initiation factor 4F complex(GO:0016281) |
| 0.0 | 1.5 | GO:0031258 | lamellipodium membrane(GO:0031258) |
| 0.0 | 0.4 | GO:0042382 | paraspeckles(GO:0042382) |
| 0.0 | 0.7 | GO:0031083 | BLOC-1 complex(GO:0031083) |
| 0.0 | 0.7 | GO:0030658 | transport vesicle membrane(GO:0030658) |
| 0.0 | 0.5 | GO:0031941 | filamentous actin(GO:0031941) |
| 0.0 | 0.4 | GO:0000164 | protein phosphatase type 1 complex(GO:0000164) |
| 0.0 | 0.3 | GO:0070938 | contractile ring(GO:0070938) |
| 0.0 | 0.6 | GO:0016010 | dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665) |
| 0.0 | 5.3 | GO:0031234 | extrinsic component of cytoplasmic side of plasma membrane(GO:0031234) |
| 0.0 | 3.3 | GO:0030672 | synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501) |
| 0.0 | 0.2 | GO:0032311 | angiogenin-PRI complex(GO:0032311) |
| 0.0 | 10.8 | GO:0005788 | endoplasmic reticulum lumen(GO:0005788) |
| 0.0 | 1.5 | GO:0097542 | ciliary tip(GO:0097542) |
| 0.0 | 0.4 | GO:0008540 | proteasome regulatory particle, base subcomplex(GO:0008540) |
| 0.0 | 0.6 | GO:0005640 | nuclear outer membrane(GO:0005640) |
| 0.0 | 0.3 | GO:0048786 | presynaptic active zone(GO:0048786) |
| 0.0 | 0.9 | GO:0032420 | stereocilium(GO:0032420) |
| 0.0 | 1.1 | GO:0042645 | nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645) |
| 0.0 | 0.2 | GO:0097136 | Bcl-2 family protein complex(GO:0097136) |
| 0.0 | 2.3 | GO:0001669 | acrosomal vesicle(GO:0001669) |
| 0.0 | 2.7 | GO:0016363 | nuclear matrix(GO:0016363) |
| 0.0 | 0.1 | GO:0000127 | transcription factor TFIIIC complex(GO:0000127) |
| 0.0 | 0.3 | GO:0001518 | voltage-gated sodium channel complex(GO:0001518) |
| 0.0 | 0.4 | GO:0031143 | pseudopodium(GO:0031143) |
| 0.0 | 0.3 | GO:0031672 | A band(GO:0031672) |
| 0.0 | 0.6 | GO:0070821 | tertiary granule membrane(GO:0070821) |
| 0.0 | 1.4 | GO:0072686 | mitotic spindle(GO:0072686) |
| 0.0 | 0.6 | GO:0031901 | early endosome membrane(GO:0031901) |
| 0.0 | 0.6 | GO:0019897 | extrinsic component of plasma membrane(GO:0019897) |
| 0.0 | 0.4 | GO:0016581 | NuRD complex(GO:0016581) CHD-type complex(GO:0090545) |
| 0.0 | 1.5 | GO:0035579 | specific granule membrane(GO:0035579) |
| 0.0 | 0.1 | GO:1990712 | HFE-transferrin receptor complex(GO:1990712) |
| 0.0 | 6.2 | GO:0005925 | focal adhesion(GO:0005925) |
| 0.0 | 0.2 | GO:0008250 | oligosaccharyltransferase complex(GO:0008250) |
| 0.0 | 0.1 | GO:0008385 | IkappaB kinase complex(GO:0008385) |
| 0.0 | 1.3 | GO:0008076 | voltage-gated potassium channel complex(GO:0008076) |
| 0.0 | 0.6 | GO:0016235 | aggresome(GO:0016235) |
| 0.0 | 0.5 | GO:0005801 | cis-Golgi network(GO:0005801) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.4 | 9.7 | GO:0030395 | lactose binding(GO:0030395) |
| 0.8 | 2.3 | GO:0050421 | cystathionine beta-synthase activity(GO:0004122) oxidoreductase activity, acting on other nitrogenous compounds as donors, cytochrome as acceptor(GO:0016662) nitrite reductase (NO-forming) activity(GO:0050421) carbon monoxide binding(GO:0070025) nitrite reductase activity(GO:0098809) |
| 0.8 | 2.3 | GO:0047696 | beta-adrenergic receptor kinase activity(GO:0047696) |
| 0.8 | 2.3 | GO:0034189 | very-low-density lipoprotein particle binding(GO:0034189) |
| 0.6 | 3.4 | GO:0010859 | calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859) |
| 0.5 | 3.8 | GO:1990254 | keratin filament binding(GO:1990254) |
| 0.5 | 9.9 | GO:0017070 | U6 snRNA binding(GO:0017070) |
| 0.5 | 2.0 | GO:0034988 | Fc-gamma receptor I complex binding(GO:0034988) |
| 0.5 | 2.5 | GO:0004489 | methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489) |
| 0.5 | 1.4 | GO:0005298 | proline:sodium symporter activity(GO:0005298) |
| 0.4 | 3.8 | GO:0048495 | Roundabout binding(GO:0048495) |
| 0.4 | 1.2 | GO:0033878 | hormone-sensitive lipase activity(GO:0033878) |
| 0.4 | 3.1 | GO:0019215 | intermediate filament binding(GO:0019215) |
| 0.4 | 1.9 | GO:0016286 | small conductance calcium-activated potassium channel activity(GO:0016286) |
| 0.4 | 1.9 | GO:0001641 | group II metabotropic glutamate receptor activity(GO:0001641) |
| 0.4 | 3.2 | GO:0086083 | cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083) |
| 0.3 | 1.3 | GO:0003974 | UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978) |
| 0.3 | 1.6 | GO:0051032 | nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033) |
| 0.3 | 0.8 | GO:0004157 | dihydropyrimidinase activity(GO:0004157) |
| 0.3 | 1.4 | GO:0060961 | phospholipase D inhibitor activity(GO:0060961) |
| 0.3 | 1.3 | GO:0004830 | tryptophan-tRNA ligase activity(GO:0004830) |
| 0.2 | 2.6 | GO:0004332 | fructose-bisphosphate aldolase activity(GO:0004332) |
| 0.2 | 4.9 | GO:0044548 | S100 protein binding(GO:0044548) |
| 0.2 | 1.8 | GO:0004111 | creatine kinase activity(GO:0004111) |
| 0.2 | 0.8 | GO:0034057 | RNA strand-exchange activity(GO:0034057) |
| 0.2 | 1.2 | GO:0051022 | GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022) |
| 0.2 | 4.3 | GO:0035615 | clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748) |
| 0.2 | 1.8 | GO:0097016 | L27 domain binding(GO:0097016) |
| 0.2 | 2.1 | GO:0038132 | neuregulin binding(GO:0038132) |
| 0.2 | 0.6 | GO:0003986 | acetyl-CoA hydrolase activity(GO:0003986) |
| 0.2 | 0.6 | GO:0005220 | inositol hexakisphosphate binding(GO:0000822) inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220) |
| 0.1 | 0.4 | GO:0000026 | alpha-1,2-mannosyltransferase activity(GO:0000026) |
| 0.1 | 1.4 | GO:0071253 | connexin binding(GO:0071253) |
| 0.1 | 3.2 | GO:0030898 | actin-dependent ATPase activity(GO:0030898) |
| 0.1 | 0.1 | GO:0016534 | cyclin-dependent protein kinase 5 activator activity(GO:0016534) |
| 0.1 | 1.1 | GO:0042731 | PH domain binding(GO:0042731) |
| 0.1 | 0.5 | GO:0099609 | microtubule lateral binding(GO:0099609) |
| 0.1 | 0.5 | GO:0050510 | N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510) |
| 0.1 | 4.9 | GO:0050431 | transforming growth factor beta binding(GO:0050431) |
| 0.1 | 1.1 | GO:0008526 | phosphatidylinositol transporter activity(GO:0008526) |
| 0.1 | 1.7 | GO:0031014 | troponin T binding(GO:0031014) |
| 0.1 | 0.4 | GO:0036361 | racemase and epimerase activity, acting on amino acids and derivatives(GO:0016855) racemase activity, acting on amino acids and derivatives(GO:0036361) amino-acid racemase activity(GO:0047661) |
| 0.1 | 0.5 | GO:0031735 | CCR10 chemokine receptor binding(GO:0031735) |
| 0.1 | 1.3 | GO:0030274 | LIM domain binding(GO:0030274) |
| 0.1 | 0.7 | GO:0005332 | gamma-aminobutyric acid:sodium symporter activity(GO:0005332) |
| 0.1 | 0.9 | GO:0004035 | alkaline phosphatase activity(GO:0004035) |
| 0.1 | 0.8 | GO:0016907 | G-protein coupled acetylcholine receptor activity(GO:0016907) |
| 0.1 | 0.3 | GO:0052593 | tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596) |
| 0.1 | 0.4 | GO:0008426 | protein kinase C inhibitor activity(GO:0008426) |
| 0.1 | 0.8 | GO:0015277 | kainate selective glutamate receptor activity(GO:0015277) |
| 0.1 | 0.9 | GO:0009922 | fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338) |
| 0.1 | 0.6 | GO:0004719 | protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719) |
| 0.1 | 0.8 | GO:1990226 | histone methyltransferase binding(GO:1990226) |
| 0.1 | 1.7 | GO:0008190 | eukaryotic initiation factor 4E binding(GO:0008190) |
| 0.1 | 1.4 | GO:0045499 | chemorepellent activity(GO:0045499) |
| 0.1 | 0.5 | GO:0004473 | malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473) |
| 0.1 | 1.7 | GO:0034450 | ubiquitin-ubiquitin ligase activity(GO:0034450) |
| 0.1 | 2.0 | GO:0005523 | tropomyosin binding(GO:0005523) |
| 0.1 | 0.2 | GO:0015235 | cobalamin transporter activity(GO:0015235) |
| 0.1 | 3.0 | GO:0005035 | tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035) |
| 0.1 | 1.1 | GO:0004596 | peptide alpha-N-acetyltransferase activity(GO:0004596) |
| 0.1 | 0.2 | GO:0042799 | histone methyltransferase activity (H4-K20 specific)(GO:0042799) |
| 0.1 | 0.4 | GO:0004594 | pantothenate kinase activity(GO:0004594) |
| 0.1 | 2.2 | GO:0005528 | macrolide binding(GO:0005527) FK506 binding(GO:0005528) |
| 0.1 | 2.8 | GO:1990841 | promoter-specific chromatin binding(GO:1990841) |
| 0.1 | 0.5 | GO:0001591 | dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591) |
| 0.1 | 2.2 | GO:0008308 | voltage-gated anion channel activity(GO:0008308) |
| 0.1 | 0.8 | GO:0019534 | toxin transporter activity(GO:0019534) |
| 0.1 | 0.4 | GO:0046912 | transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912) |
| 0.1 | 0.3 | GO:0008401 | retinoic acid 4-hydroxylase activity(GO:0008401) |
| 0.1 | 1.7 | GO:0030553 | cGMP binding(GO:0030553) |
| 0.1 | 0.6 | GO:0047498 | calcium-dependent phospholipase A2 activity(GO:0047498) |
| 0.1 | 0.6 | GO:0001135 | transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135) |
| 0.0 | 0.2 | GO:0001632 | leukotriene B4 receptor activity(GO:0001632) |
| 0.0 | 5.2 | GO:0008307 | structural constituent of muscle(GO:0008307) |
| 0.0 | 1.1 | GO:0017049 | GTP-Rho binding(GO:0017049) |
| 0.0 | 7.2 | GO:0005200 | structural constituent of cytoskeleton(GO:0005200) |
| 0.0 | 0.8 | GO:0047372 | acylglycerol lipase activity(GO:0047372) |
| 0.0 | 5.1 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
| 0.0 | 0.5 | GO:0045294 | alpha-catenin binding(GO:0045294) |
| 0.0 | 1.0 | GO:0031005 | filamin binding(GO:0031005) |
| 0.0 | 0.4 | GO:1990380 | Lys48-specific deubiquitinase activity(GO:1990380) |
| 0.0 | 1.4 | GO:0005123 | death receptor binding(GO:0005123) |
| 0.0 | 0.1 | GO:0017018 | myosin phosphatase activity(GO:0017018) |
| 0.0 | 0.7 | GO:0015095 | magnesium ion transmembrane transporter activity(GO:0015095) |
| 0.0 | 0.4 | GO:0071933 | Arp2/3 complex binding(GO:0071933) |
| 0.0 | 0.6 | GO:0005328 | neurotransmitter:sodium symporter activity(GO:0005328) |
| 0.0 | 0.1 | GO:0004998 | transferrin receptor activity(GO:0004998) |
| 0.0 | 4.1 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
| 0.0 | 0.5 | GO:0003688 | DNA replication origin binding(GO:0003688) |
| 0.0 | 0.7 | GO:0034236 | protein kinase A catalytic subunit binding(GO:0034236) |
| 0.0 | 0.4 | GO:0016884 | carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884) |
| 0.0 | 0.5 | GO:0008179 | adenylate cyclase binding(GO:0008179) |
| 0.0 | 0.2 | GO:0071532 | ankyrin repeat binding(GO:0071532) |
| 0.0 | 5.2 | GO:0017124 | SH3 domain binding(GO:0017124) |
| 0.0 | 0.4 | GO:0031748 | D1 dopamine receptor binding(GO:0031748) |
| 0.0 | 3.0 | GO:0008081 | phosphoric diester hydrolase activity(GO:0008081) |
| 0.0 | 0.6 | GO:0019707 | protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707) |
| 0.0 | 1.3 | GO:0004693 | cyclin-dependent protein serine/threonine kinase activity(GO:0004693) |
| 0.0 | 0.7 | GO:0071889 | 14-3-3 protein binding(GO:0071889) |
| 0.0 | 1.2 | GO:0003899 | DNA-directed RNA polymerase activity(GO:0003899) |
| 0.0 | 0.7 | GO:0002039 | p53 binding(GO:0002039) |
| 0.0 | 0.3 | GO:0001075 | transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075) |
| 0.0 | 7.8 | GO:0003924 | GTPase activity(GO:0003924) |
| 0.0 | 0.2 | GO:0000405 | bubble DNA binding(GO:0000405) |
| 0.0 | 0.3 | GO:0097109 | neuroligin family protein binding(GO:0097109) |
| 0.0 | 0.5 | GO:0001965 | G-protein alpha-subunit binding(GO:0001965) |
| 0.0 | 0.1 | GO:0010465 | nerve growth factor receptor activity(GO:0010465) |
| 0.0 | 7.2 | GO:0045296 | cadherin binding(GO:0045296) |
| 0.0 | 0.4 | GO:0048018 | receptor agonist activity(GO:0048018) |
| 0.0 | 0.1 | GO:0004865 | protein serine/threonine phosphatase inhibitor activity(GO:0004865) |
| 0.0 | 0.6 | GO:0008574 | ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) |
| 0.0 | 0.2 | GO:0005049 | nuclear export signal receptor activity(GO:0005049) |
| 0.0 | 11.2 | GO:0005198 | structural molecule activity(GO:0005198) |
| 0.0 | 0.5 | GO:0043325 | phosphatidylinositol-3,4-bisphosphate binding(GO:0043325) |
| 0.0 | 0.4 | GO:0008242 | omega peptidase activity(GO:0008242) |
| 0.0 | 1.4 | GO:0003777 | microtubule motor activity(GO:0003777) |
| 0.0 | 0.7 | GO:0097110 | scaffold protein binding(GO:0097110) |
| 0.0 | 0.4 | GO:0003785 | actin monomer binding(GO:0003785) |
| 0.0 | 1.2 | GO:0004715 | non-membrane spanning protein tyrosine kinase activity(GO:0004715) |
| 0.0 | 0.2 | GO:0008428 | ribonuclease inhibitor activity(GO:0008428) |
| 0.0 | 0.1 | GO:0004052 | arachidonate 12-lipoxygenase activity(GO:0004052) |
| 0.0 | 0.4 | GO:0008139 | nuclear localization sequence binding(GO:0008139) |
| 0.0 | 1.9 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
| 0.0 | 0.4 | GO:0008157 | protein phosphatase 1 binding(GO:0008157) |
| 0.0 | 0.1 | GO:0097001 | glycosphingolipid binding(GO:0043208) ceramide binding(GO:0097001) |
| 0.0 | 0.3 | GO:0031402 | sodium ion binding(GO:0031402) |
| 0.0 | 0.1 | GO:0070740 | tubulin-glutamic acid ligase activity(GO:0070740) |
| 0.0 | 0.4 | GO:0004709 | MAP kinase kinase kinase activity(GO:0004709) |
| 0.0 | 0.1 | GO:0061133 | endopeptidase activator activity(GO:0061133) |
| 0.0 | 0.4 | GO:0004602 | glutathione peroxidase activity(GO:0004602) |
| 0.0 | 0.3 | GO:0000400 | four-way junction DNA binding(GO:0000400) |
| 0.0 | 0.7 | GO:0048306 | calcium-dependent protein binding(GO:0048306) |
| 0.0 | 3.2 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
| 0.0 | 0.4 | GO:0042287 | MHC protein binding(GO:0042287) |
| 0.0 | 0.1 | GO:0048407 | platelet-derived growth factor binding(GO:0048407) |
| 0.0 | 0.3 | GO:0004653 | polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 6.0 | PID_INTEGRIN4_PATHWAY | Alpha6 beta4 integrin-ligand interactions |
| 0.2 | 9.9 | PID_RAS_PATHWAY | Regulation of Ras family activation |
| 0.1 | 8.5 | PID_PI3K_PLC_TRK_PATHWAY | Trk receptor signaling mediated by PI3K and PLC-gamma |
| 0.1 | 9.9 | PID_ECADHERIN_NASCENT_AJ_PATHWAY | E-cadherin signaling in the nascent adherens junction |
| 0.1 | 0.2 | PID_S1P_S1P1_PATHWAY | S1P1 pathway |
| 0.1 | 4.4 | PID_ALPHA_SYNUCLEIN_PATHWAY | Alpha-synuclein signaling |
| 0.1 | 1.4 | PID_NECTIN_PATHWAY | Nectin adhesion pathway |
| 0.1 | 6.1 | PID_NOTCH_PATHWAY | Notch signaling pathway |
| 0.1 | 4.3 | PID_AURORA_B_PATHWAY | Aurora B signaling |
| 0.1 | 2.4 | PID_EPHB_FWD_PATHWAY | EPHB forward signaling |
| 0.1 | 4.7 | PID_TAP63_PATHWAY | Validated transcriptional targets of TAp63 isoforms |
| 0.1 | 3.1 | SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES | Genes related to regulation of the actin cytoskeleton |
| 0.0 | 1.7 | PID_RHODOPSIN_PATHWAY | Visual signal transduction: Rods |
| 0.0 | 0.5 | PID_P38_GAMMA_DELTA_PATHWAY | Signaling mediated by p38-gamma and p38-delta |
| 0.0 | 1.0 | PID_PRL_SIGNALING_EVENTS_PATHWAY | Signaling events mediated by PRL |
| 0.0 | 0.9 | PID_RHOA_PATHWAY | RhoA signaling pathway |
| 0.0 | 0.5 | ST_G_ALPHA_I_PATHWAY | G alpha i Pathway |
| 0.0 | 0.7 | PID_WNT_CANONICAL_PATHWAY | Canonical Wnt signaling pathway |
| 0.0 | 3.3 | PID_AR_PATHWAY | Coregulation of Androgen receptor activity |
| 0.0 | 1.0 | ST_MYOCYTE_AD_PATHWAY | Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway. |
| 0.0 | 1.4 | PID_FOXM1_PATHWAY | FOXM1 transcription factor network |
| 0.0 | 8.6 | NABA_ECM_REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
| 0.0 | 0.6 | PID_IL8_CXCR1_PATHWAY | IL8- and CXCR1-mediated signaling events |
| 0.0 | 1.3 | PID_FAK_PATHWAY | Signaling events mediated by focal adhesion kinase |
| 0.0 | 0.9 | ST_B_CELL_ANTIGEN_RECEPTOR | B Cell Antigen Receptor |
| 0.0 | 2.0 | PID_HIF1_TFPATHWAY | HIF-1-alpha transcription factor network |
| 0.0 | 1.5 | PID_INTEGRIN1_PATHWAY | Beta1 integrin cell surface interactions |
| 0.0 | 3.4 | PID_P53_DOWNSTREAM_PATHWAY | Direct p53 effectors |
| 0.0 | 0.2 | PID_PDGFRA_PATHWAY | PDGFR-alpha signaling pathway |
| 0.0 | 0.8 | PID_NFAT_3PATHWAY | Role of Calcineurin-dependent NFAT signaling in lymphocytes |
| 0.0 | 0.7 | PID_CDC42_REG_PATHWAY | Regulation of CDC42 activity |
| 0.0 | 0.2 | PID_SYNDECAN_2_PATHWAY | Syndecan-2-mediated signaling events |
| 0.0 | 0.4 | PID_P38_MKK3_6PATHWAY | p38 MAPK signaling pathway |
| 0.0 | 0.4 | PID_CIRCADIAN_PATHWAY | Circadian rhythm pathway |
| 0.0 | 0.8 | PID_P73PATHWAY | p73 transcription factor network |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 9.5 | REACTOME_PTM_GAMMA_CARBOXYLATION_HYPUSINE_FORMATION_AND_ARYLSULFATASE_ACTIVATION | Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation |
| 0.2 | 4.3 | REACTOME_RETROGRADE_NEUROTROPHIN_SIGNALLING | Genes involved in Retrograde neurotrophin signalling |
| 0.2 | 2.9 | REACTOME_APOPTOTIC_CLEAVAGE_OF_CELL_ADHESION_PROTEINS | Genes involved in Apoptotic cleavage of cell adhesion proteins |
| 0.2 | 5.7 | REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS | Genes involved in Caspase-mediated cleavage of cytoskeletal proteins |
| 0.1 | 2.7 | REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS | Genes involved in Na+/Cl- dependent neurotransmitter transporters |
| 0.1 | 2.9 | REACTOME_DESTABILIZATION_OF_MRNA_BY_KSRP | Genes involved in Destabilization of mRNA by KSRP |
| 0.1 | 1.9 | REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS | Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors) |
| 0.1 | 5.2 | REACTOME_SMOOTH_MUSCLE_CONTRACTION | Genes involved in Smooth Muscle Contraction |
| 0.1 | 3.1 | REACTOME_SEMA4D_INDUCED_CELL_MIGRATION_AND_GROWTH_CONE_COLLAPSE | Genes involved in Sema4D induced cell migration and growth-cone collapse |
| 0.1 | 2.1 | REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS | Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis |
| 0.1 | 2.5 | REACTOME_RNA_POL_I_TRANSCRIPTION_TERMINATION | Genes involved in RNA Polymerase I Transcription Termination |
| 0.1 | 1.4 | REACTOME_P38MAPK_EVENTS | Genes involved in p38MAPK events |
| 0.1 | 0.9 | REACTOME_ERKS_ARE_INACTIVATED | Genes involved in ERKs are inactivated |
| 0.1 | 2.0 | REACTOME_KINESINS | Genes involved in Kinesins |
| 0.1 | 1.1 | REACTOME_G2_M_DNA_DAMAGE_CHECKPOINT | Genes involved in G2/M DNA damage checkpoint |
| 0.1 | 1.0 | REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS | Genes involved in Ionotropic activity of Kainate Receptors |
| 0.1 | 2.3 | REACTOME_GLYCOLYSIS | Genes involved in Glycolysis |
| 0.0 | 0.6 | REACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS | Genes involved in Elevation of cytosolic Ca2+ levels |
| 0.0 | 1.0 | REACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI | Genes involved in Pre-NOTCH Processing in Golgi |
| 0.0 | 0.5 | REACTOME_E2F_ENABLED_INHIBITION_OF_PRE_REPLICATION_COMPLEX_FORMATION | Genes involved in E2F-enabled inhibition of pre-replication complex formation |
| 0.0 | 1.0 | REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS | Genes involved in Cell-extracellular matrix interactions |
| 0.0 | 1.3 | REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION | Genes involved in Cytosolic tRNA aminoacylation |
| 0.0 | 1.1 | REACTOME_NEPHRIN_INTERACTIONS | Genes involved in Nephrin interactions |
| 0.0 | 0.9 | REACTOME_SYNTHESIS_OF_VERY_LONG_CHAIN_FATTY_ACYL_COAS | Genes involved in Synthesis of very long-chain fatty acyl-CoAs |
| 0.0 | 0.9 | REACTOME_SEMA3A_PAK_DEPENDENT_AXON_REPULSION | Genes involved in Sema3A PAK dependent Axon repulsion |
| 0.0 | 0.9 | REACTOME_PHOSPHORYLATION_OF_CD3_AND_TCR_ZETA_CHAINS | Genes involved in Phosphorylation of CD3 and TCR zeta chains |
| 0.0 | 1.1 | REACTOME_CHONDROITIN_SULFATE_BIOSYNTHESIS | Genes involved in Chondroitin sulfate biosynthesis |
| 0.0 | 0.7 | REACTOME_RECYCLING_PATHWAY_OF_L1 | Genes involved in Recycling pathway of L1 |
| 0.0 | 0.6 | REACTOME_ADENYLATE_CYCLASE_INHIBITORY_PATHWAY | Genes involved in Adenylate cyclase inhibitory pathway |
| 0.0 | 2.0 | REACTOME_NCAM1_INTERACTIONS | Genes involved in NCAM1 interactions |
| 0.0 | 2.7 | REACTOME_CELL_JUNCTION_ORGANIZATION | Genes involved in Cell junction organization |
| 0.0 | 1.4 | REACTOME_MUSCLE_CONTRACTION | Genes involved in Muscle contraction |
| 0.0 | 0.4 | REACTOME_IRAK1_RECRUITS_IKK_COMPLEX | Genes involved in IRAK1 recruits IKK complex |
| 0.0 | 0.8 | REACTOME_POST_CHAPERONIN_TUBULIN_FOLDING_PATHWAY | Genes involved in Post-chaperonin tubulin folding pathway |
| 0.0 | 1.9 | REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS | Genes involved in Metabolism of vitamins and cofactors |
| 0.0 | 0.4 | REACTOME_FORMATION_OF_INCISION_COMPLEX_IN_GG_NER | Genes involved in Formation of incision complex in GG-NER |
| 0.0 | 0.9 | REACTOME_COLLAGEN_FORMATION | Genes involved in Collagen formation |
| 0.0 | 0.7 | REACTOME_AMINE_LIGAND_BINDING_RECEPTORS | Genes involved in Amine ligand-binding receptors |
| 0.0 | 1.5 | REACTOME_ACTIVATION_OF_THE_MRNA_UPON_BINDING_OF_THE_CAP_BINDING_COMPLEX_AND_EIFS_AND_SUBSEQUENT_BINDING_TO_43S | Genes involved in Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S |
| 0.0 | 0.4 | REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE | Genes involved in Citric acid cycle (TCA cycle) |
| 0.0 | 0.5 | REACTOME_SIGNAL_REGULATORY_PROTEIN_SIRP_FAMILY_INTERACTIONS | Genes involved in Signal regulatory protein (SIRP) family interactions |
| 0.0 | 1.6 | REACTOME_P75_NTR_RECEPTOR_MEDIATED_SIGNALLING | Genes involved in p75 NTR receptor-mediated signalling |
| 0.0 | 0.5 | REACTOME_SIGNALING_BY_ROBO_RECEPTOR | Genes involved in Signaling by Robo receptor |
| 0.0 | 1.1 | REACTOME_MEIOTIC_SYNAPSIS | Genes involved in Meiotic Synapsis |
| 0.0 | 0.4 | REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES | Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates |
