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Motif ID: KLF12

Z-value: 1.186

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr15_+_89402148	2.933	ENST00000560601.1	ACAN	aggrecan
chr2_+_234104079	2.877	ENST00000417661.1	INPP5D	inositol polyphosphate-5-phosphatase, 145kDa
chr15_-_90039805	2.854	ENST00000544600.1 ENST00000268122.4	RHCG	Rh family, C glycoprotein
chr8_+_22022800	2.307	ENST00000397814.3	BMP1	bone morphogenetic protein 1
chrX_-_48325857	2.266	ENST00000376875.1	SLC38A5	solute carrier family 38, member 5
chr17_-_76899275	1.900	ENST00000322630.2 ENST00000586713.1	DDC8	Protein DDC8 homolog
chr1_-_47655686	1.710	ENST00000294338.2	PDZK1IP1	PDZK1 interacting protein 1
chr2_+_24272543	1.644	ENST00000380991.4	FKBP1B	FK506 binding protein 1B, 12.6 kDa
chr2_+_24272576	1.644	ENST00000380986.4 ENST00000452109.1	FKBP1B	FK506 binding protein 1B, 12.6 kDa
chr17_+_7211280	1.582	ENST00000419711.2 ENST00000571955.1 ENST00000573714.1	EIF5A	eukaryotic translation initiation factor 5A
chr14_+_65171315	1.458	ENST00000394691.1	PLEKHG3	pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr12_-_54778471	1.297	ENST00000550120.1 ENST00000394313.2 ENST00000547210.1	ZNF385A	zinc finger protein 385A
chr8_+_124194875	1.295	ENST00000522648.1 ENST00000276699.6	FAM83A	family with sequence similarity 83, member A
chr18_-_31628558	1.292	ENST00000535384.1	NOL4	nucleolar protein 4
chr8_+_124194752	1.254	ENST00000318462.6	FAM83A	family with sequence similarity 83, member A
chr1_+_155178481	1.232	ENST00000368376.3	MTX1	metaxin 1
chr20_+_44637526	1.221	ENST00000372330.3	MMP9	matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
chr1_+_155178518	1.204	ENST00000316721.4	MTX1	metaxin 1
chr22_+_31489344	1.154	ENST00000404574.1	SMTN	smoothelin
chr17_+_1665253	1.133	ENST00000254722.4	SERPINF1	serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr17_+_7210921	1.080	ENST00000573542.1	EIF5A	eukaryotic translation initiation factor 5A
chr17_+_1665345	1.078	ENST00000576406.1 ENST00000571149.1	SERPINF1	serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr7_+_2687173	1.067	ENST00000403167.1	TTYH3	tweety family member 3
chr7_+_143013198	1.061	ENST00000343257.2	CLCN1	chloride channel, voltage-sensitive 1
chr2_+_90458201	1.060	ENST00000603238.1	CH17-132F21.1	Uncharacterized protein
chr3_-_52567792	1.058	ENST00000307092.4 ENST00000422318.2 ENST00000459839.1	NT5DC2	5'-nucleotidase domain containing 2
chr9_+_131084846	1.014	ENST00000608951.1	COQ4	coenzyme Q4
chr17_+_7210852	1.008	ENST00000576930.1	EIF5A	eukaryotic translation initiation factor 5A
chr15_+_74218787	0.998	ENST00000261921.7	LOXL1	lysyl oxidase-like 1
chr1_+_50574585	0.991	ENST00000371824.1 ENST00000371823.4	ELAVL4	ELAV like neuron-specific RNA binding protein 4
chr11_-_57089671	0.984	ENST00000532437.1	TNKS1BP1	tankyrase 1 binding protein 1, 182kDa
chr11_-_568369	0.954	ENST00000534540.1 ENST00000528245.1 ENST00000500447.1 ENST00000533920.1	MIR210HG	MIR210 host gene (non-protein coding)
chr8_+_22022653	0.951	ENST00000354870.5 ENST00000397816.3 ENST00000306349.8	BMP1	bone morphogenetic protein 1
chr14_+_74417192	0.949	ENST00000554320.1	COQ6	coenzyme Q6 monooxygenase
chr12_-_57328187	0.930	ENST00000293502.1	SDR9C7	short chain dehydrogenase/reductase family 9C, member 7
chr11_-_1643368	0.917	ENST00000399682.1	KRTAP5-4	keratin associated protein 5-4
chr2_-_192711968	0.915	ENST00000304141.4	SDPR	serum deprivation response
chr17_-_39637392	0.897	ENST00000246639.2 ENST00000393989.1	KRT35	keratin 35
chr9_-_131085021	0.897	ENST00000372890.4	TRUB2	TruB pseudouridine (psi) synthase family member 2
chr20_+_58152524	0.890	ENST00000359926.3	PHACTR3	phosphatase and actin regulator 3
chr17_-_36831156	0.885	ENST00000325814.5	C17orf96	chromosome 17 open reading frame 96
chr12_-_67072714	0.883	ENST00000545666.1 ENST00000398016.3 ENST00000359742.4 ENST00000286445.7 ENST00000538211.1	GRIP1	glutamate receptor interacting protein 1
chr3_+_52350335	0.872	ENST00000420323.2	DNAH1	dynein, axonemal, heavy chain 1
chr4_+_128702969	0.859	ENST00000508776.1 ENST00000439123.2	HSPA4L	heat shock 70kDa protein 4-like
chr4_-_74904398	0.852	ENST00000296026.4	CXCL3	chemokine (C-X-C motif) ligand 3
chr17_+_7210898	0.839	ENST00000572815.1	EIF5A	eukaryotic translation initiation factor 5A
chr22_-_37640456	0.803	ENST00000405484.1 ENST00000441619.1 ENST00000406508.1	RAC2	ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr5_+_34656331	0.803	ENST00000265109.3	RAI14	retinoic acid induced 14
chr9_-_99064386	0.799	ENST00000375262.2	HSD17B3	hydroxysteroid (17-beta) dehydrogenase 3
chr22_-_50524298	0.799	ENST00000311597.5	MLC1	megalencephalic leukoencephalopathy with subcortical cysts 1
chr5_-_139930713	0.799	ENST00000602657.1	SRA1	steroid receptor RNA activator 1
chrX_+_152953505	0.799	ENST00000253122.5	SLC6A8	solute carrier family 6 (neurotransmitter transporter), member 8
chr16_+_28889801	0.797	ENST00000395503.4	ATP2A1	ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
chr22_-_38699003	0.795	ENST00000451964.1	CSNK1E	casein kinase 1, epsilon
chr1_-_155177677	0.775	ENST00000368378.3 ENST00000541990.1 ENST00000457183.2	THBS3	thrombospondin 3
chrX_+_49028265	0.774	ENST00000376322.3 ENST00000376327.5	PLP2	proteolipid protein 2 (colonic epithelium-enriched)
chr16_+_28889703	0.770	ENST00000357084.3	ATP2A1	ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
chr4_+_4387983	0.761	ENST00000397958.1	NSG1	Homo sapiens neuron specific gene family member 1 (NSG1), transcript variant 3, mRNA.
chr6_+_101847105	0.757	ENST00000369137.3 ENST00000318991.6	GRIK2	glutamate receptor, ionotropic, kainate 2
chr14_+_85996471	0.755	ENST00000330753.4	FLRT2	fibronectin leucine rich transmembrane protein 2
chr11_-_66103867	0.731	ENST00000424433.2	RIN1	Ras and Rab interactor 1
chr12_+_50366620	0.726	ENST00000315520.5	AQP6	aquaporin 6, kidney specific
chr17_-_41174424	0.685	ENST00000355653.3	VAT1	vesicle amine transport 1
chr19_+_45174994	0.681	ENST00000403660.3	CEACAM19	carcinoembryonic antigen-related cell adhesion molecule 19
chr19_+_45174724	0.679	ENST00000358777.4	CEACAM19	carcinoembryonic antigen-related cell adhesion molecule 19
chr1_+_32687971	0.679	ENST00000373586.1	EIF3I	eukaryotic translation initiation factor 3, subunit I
chr10_+_99473455	0.673	ENST00000285605.6	MARVELD1	MARVEL domain containing 1
chr10_+_81272287	0.669	ENST00000520547.2	EIF5AL1	eukaryotic translation initiation factor 5A-like 1
chr9_+_116207007	0.662	ENST00000374140.2	RGS3	regulator of G-protein signaling 3
chr9_-_34637806	0.661	ENST00000477726.1	SIGMAR1	sigma non-opioid intracellular receptor 1
chr19_-_45909585	0.660	ENST00000593226.1 ENST00000418234.2	PPP1R13L	protein phosphatase 1, regulatory subunit 13 like
chr3_-_182703688	0.656	ENST00000466812.1 ENST00000487822.1 ENST00000460412.1 ENST00000469954.1	DCUN1D1	DCN1, defective in cullin neddylation 1, domain containing 1
chr14_+_65171099	0.654	ENST00000247226.7	PLEKHG3	pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr6_-_66417107	0.653	ENST00000370621.3 ENST00000370618.3 ENST00000503581.1 ENST00000393380.2	EYS	eyes shut homolog (Drosophila)
chr5_+_34656569	0.640	ENST00000428746.2	RAI14	retinoic acid induced 14
chr3_+_50316458	0.639	ENST00000316436.3	LSMEM2	leucine-rich single-pass membrane protein 2
chr9_-_99064429	0.636	ENST00000375263.3	HSD17B3	hydroxysteroid (17-beta) dehydrogenase 3
chr9_+_116267536	0.629	ENST00000374136.1	RGS3	regulator of G-protein signaling 3
chr14_+_96343100	0.628	ENST00000503525.2	LINC00617	long intergenic non-protein coding RNA 617
chr7_+_142458507	0.626	ENST00000492062.1	PRSS1	protease, serine, 1 (trypsin 1)
chr11_+_66360665	0.624	ENST00000310190.4	CCS	copper chaperone for superoxide dismutase
chr4_+_128703295	0.624	ENST00000296464.4 ENST00000508549.1	HSPA4L	heat shock 70kDa protein 4-like
chr17_+_79989937	0.613	ENST00000580965.1	RAC3	ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
chr12_-_96184533	0.612	ENST00000343702.4 ENST00000344911.4	NTN4	netrin 4
chr1_-_19229014	0.597	ENST00000538839.1 ENST00000290597.5	ALDH4A1	aldehyde dehydrogenase 4 family, member A1
chr16_-_67360662	0.589	ENST00000304372.5	KCTD19	potassium channel tetramerization domain containing 19
chr1_+_16083154	0.583	ENST00000375771.1	FBLIM1	filamin binding LIM protein 1
chr5_+_167181917	0.580	ENST00000519204.1	TENM2	teneurin transmembrane protein 2
chrX_+_68048803	0.575	ENST00000204961.4	EFNB1	ephrin-B1
chr11_-_2160180	0.566	ENST00000381406.4	IGF2	insulin-like growth factor 2 (somatomedin A)
chr1_-_31661000	0.560	ENST00000263693.1 ENST00000398657.2 ENST00000526106.1	NKAIN1	Na+/K+ transporting ATPase interacting 1
chrX_-_134186144	0.556	ENST00000370775.2	FAM127B	family with sequence similarity 127, member B
chr11_+_71164149	0.553	ENST00000319023.2	NADSYN1	NAD synthetase 1
chr1_-_205904950	0.548	ENST00000340781.4	SLC26A9	solute carrier family 26 (anion exchanger), member 9
chrX_-_134156502	0.547	ENST00000391440.1	FAM127C	family with sequence similarity 127, member C
chr19_-_49926698	0.542	ENST00000270631.1	PTH2	parathyroid hormone 2
chr16_-_67978016	0.542	ENST00000264005.5	LCAT	lecithin-cholesterol acyltransferase
chr14_+_74416989	0.540	ENST00000334571.2 ENST00000554920.1	COQ6	coenzyme Q6 monooxygenase
chr3_+_130569592	0.524	ENST00000533801.2	ATP2C1	ATPase, Ca++ transporting, type 2C, member 1
chr6_+_35995552	0.521	ENST00000468133.1	MAPK14	mitogen-activated protein kinase 14
chrX_+_47082408	0.517	ENST00000518022.1 ENST00000276052.6	CDK16	cyclin-dependent kinase 16
chr17_-_7155274	0.514	ENST00000318988.6 ENST00000575783.1 ENST00000573600.1	CTDNEP1	CTD nuclear envelope phosphatase 1
chr17_-_39150385	0.512	ENST00000391586.1	KRTAP3-3	keratin associated protein 3-3
chr14_+_75469606	0.511	ENST00000266126.5	EIF2B2	eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa
chr5_+_52776228	0.507	ENST00000256759.3	FST	follistatin
chr11_+_117070037	0.505	ENST00000392951.4 ENST00000525531.1 ENST00000278968.6	TAGLN	transgelin
chr1_-_216596738	0.502	ENST00000307340.3 ENST00000366943.2 ENST00000366942.3	USH2A	Usher syndrome 2A (autosomal recessive, mild)
chr1_-_32687923	0.493	ENST00000309777.6 ENST00000344461.3 ENST00000373593.1 ENST00000545122.1	TMEM234	transmembrane protein 234
chr17_-_7154984	0.482	ENST00000574322.1	CTDNEP1	CTD nuclear envelope phosphatase 1
chr6_-_27775694	0.481	ENST00000377401.2	HIST1H2BL	histone cluster 1, H2bl
chr3_-_48057890	0.478	ENST00000434267.1	MAP4	microtubule-associated protein 4
chr1_+_109792641	0.477	ENST00000271332.3	CELSR2	cadherin, EGF LAG seven-pass G-type receptor 2
chr17_-_73840415	0.474	ENST00000592386.1 ENST00000412096.2 ENST00000586147.1	UNC13D	unc-13 homolog D (C. elegans)
chr12_+_121416340	0.471	ENST00000257555.6 ENST00000400024.2	HNF1A	HNF1 homeobox A
chr12_+_27677085	0.468	ENST00000545334.1 ENST00000540114.1 ENST00000537927.1 ENST00000318304.8 ENST00000535047.1 ENST00000542629.1 ENST00000228425.6	PPFIBP1	PTPRF interacting protein, binding protein 1 (liprin beta 1)
chr16_+_30671223	0.462	ENST00000568722.1	FBRS	fibrosin
chrX_+_152086373	0.461	ENST00000318529.8	ZNF185	zinc finger protein 185 (LIM domain)
chr17_-_36906058	0.459	ENST00000580830.1	PCGF2	polycomb group ring finger 2
chr16_+_69140122	0.458	ENST00000219322.3	HAS3	hyaluronan synthase 3
chr20_-_30433396	0.452	ENST00000375978.3	FOXS1	forkhead box S1
chr7_+_107220660	0.450	ENST00000465919.1 ENST00000445771.2 ENST00000479917.1 ENST00000421217.1 ENST00000457837.1	BCAP29	B-cell receptor-associated protein 29
chr20_+_34713312	0.448	ENST00000373946.3	EPB41L1	erythrocyte membrane protein band 4.1-like 1
chr12_+_121416489	0.448	ENST00000541395.1 ENST00000544413.1	HNF1A	HNF1 homeobox A
chr14_+_22748980	0.447	ENST00000390465.2	TRAV38-2DV8	T cell receptor alpha variable 38-2/delta variable 8
chr8_-_143857402	0.446	ENST00000523332.1	LYNX1	Ly6/neurotoxin 1
chr5_+_74633036	0.444	ENST00000343975.5	HMGCR	3-hydroxy-3-methylglutaryl-CoA reductase
chr14_-_74416829	0.437	ENST00000534936.1	FAM161B	family with sequence similarity 161, member B
chr2_+_219745020	0.436	ENST00000258411.3	WNT10A	wingless-type MMTV integration site family, member 10A
chr17_-_40829026	0.435	ENST00000412503.1	PLEKHH3	pleckstrin homology domain containing, family H (with MyTH4 domain) member 3
chr10_-_77161004	0.428	ENST00000418818.2	RP11-399K21.11	RP11-399K21.11
chr9_+_126131131	0.424	ENST00000373629.2	CRB2	crumbs homolog 2 (Drosophila)
chr13_-_67804445	0.423	ENST00000456367.1 ENST00000377861.3 ENST00000544246.1	PCDH9	protocadherin 9
chr16_+_30194916	0.423	ENST00000570045.1 ENST00000565497.1 ENST00000570244.1	CORO1A	coronin, actin binding protein, 1A
chr11_-_65374430	0.422	ENST00000532507.1	MAP3K11	mitogen-activated protein kinase kinase kinase 11
chr13_-_67802549	0.417	ENST00000328454.5 ENST00000377865.2	PCDH9	protocadherin 9
chr1_+_55013889	0.414	ENST00000343744.2 ENST00000371316.3	ACOT11	acyl-CoA thioesterase 11
chr11_-_66360548	0.407	ENST00000333861.3	CCDC87	coiled-coil domain containing 87
chr6_+_35773070	0.407	ENST00000373853.1 ENST00000360215.1	LHFPL5	lipoma HMGIC fusion partner-like 5
chr6_+_35995531	0.406	ENST00000229794.4	MAPK14	mitogen-activated protein kinase 14
chr11_+_71249071	0.405	ENST00000398534.3	KRTAP5-8	keratin associated protein 5-8
chr1_-_203274418	0.403	ENST00000457348.1	RP11-134P9.1	long intergenic non-protein coding RNA 1136
chr7_+_123295861	0.401	ENST00000458573.2 ENST00000456238.2	LMOD2	leiomodin 2 (cardiac)
chr8_-_37797621	0.400	ENST00000524298.1 ENST00000307599.4	GOT1L1	glutamic-oxaloacetic transaminase 1-like 1
chr11_+_62475130	0.396	ENST00000294117.5	GNG3	guanine nucleotide binding protein (G protein), gamma 3
chr16_-_29875057	0.392	ENST00000219789.6	CDIPT	CDP-diacylglycerol--inositol 3-phosphatidyltransferase
chr17_-_40828969	0.388	ENST00000591022.1 ENST00000587627.1 ENST00000293349.6	PLEKHH3	pleckstrin homology domain containing, family H (with MyTH4 domain) member 3
chr14_+_61788429	0.387	ENST00000332981.5	PRKCH	protein kinase C, eta
chr17_-_57784755	0.381	ENST00000537860.1 ENST00000393038.2 ENST00000409433.2	PTRH2	peptidyl-tRNA hydrolase 2
chr5_-_180632147	0.381	ENST00000274773.7	TRIM7	tripartite motif containing 7
chrX_-_70288234	0.377	ENST00000276105.3 ENST00000374274.3	SNX12	sorting nexin 12
chr9_-_34637718	0.377	ENST00000378892.1 ENST00000277010.4	SIGMAR1	sigma non-opioid intracellular receptor 1
chr10_+_104155450	0.376	ENST00000471698.1 ENST00000189444.6	NFKB2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
chr7_-_140178775	0.375	ENST00000474576.1 ENST00000473444.1 ENST00000471104.1	MKRN1	makorin ring finger protein 1
chr3_-_99833333	0.375	ENST00000354552.3 ENST00000331335.5 ENST00000398326.2	FILIP1L	filamin A interacting protein 1-like
chr5_+_169780485	0.370	ENST00000377360.4	KCNIP1	Kv channel interacting protein 1
chr2_-_89247338	0.366	ENST00000496168.1	IGKV1-5	immunoglobulin kappa variable 1-5
chr14_+_23563952	0.362	ENST00000319074.4	C14orf119	chromosome 14 open reading frame 119
chr12_+_107168418	0.357	ENST00000392839.2 ENST00000548914.1 ENST00000355478.2 ENST00000552619.1 ENST00000549643.1	RIC8B	RIC8 guanine nucleotide exchange factor B
chr2_-_208634287	0.356	ENST00000295417.3	FZD5	frizzled family receptor 5
chr8_-_101962777	0.356	ENST00000395951.3	YWHAZ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
chr17_+_900342	0.353	ENST00000327158.4	TIMM22	translocase of inner mitochondrial membrane 22 homolog (yeast)
chr10_-_77161650	0.351	ENST00000372524.4	ZNF503	zinc finger protein 503
chr10_-_77161533	0.349	ENST00000535216.1	ZNF503	zinc finger protein 503
chr3_-_51994694	0.349	ENST00000395014.2	PCBP4	poly(rC) binding protein 4
chr20_-_656437	0.348	ENST00000488788.2	RP5-850E9.3	Uncharacterized protein
chr6_-_43021612	0.345	ENST00000535468.1	CUL7	cullin 7
chr7_+_107220899	0.344	ENST00000379117.2 ENST00000473124.1	BCAP29	B-cell receptor-associated protein 29
chr17_+_17942594	0.339	ENST00000268719.4	GID4	GID complex subunit 4
chr6_-_30640811	0.339	ENST00000376442.3	DHX16	DEAH (Asp-Glu-Ala-His) box polypeptide 16
chr16_+_1291240	0.337	ENST00000561736.1	TPSAB1	tryptase alpha/beta 1
chr5_+_74632993	0.331	ENST00000287936.4	HMGCR	3-hydroxy-3-methylglutaryl-CoA reductase
chr11_+_65154070	0.330	ENST00000317568.5 ENST00000531296.1 ENST00000533782.1 ENST00000355991.5 ENST00000416776.2 ENST00000526201.1	FRMD8	FERM domain containing 8
chr6_+_31895467	0.328	ENST00000556679.1 ENST00000456570.1	CFB CFB	complement factor B Complement factor B; Uncharacterized protein; cDNA FLJ55673, highly similar to Complement factor B
chr15_-_34394119	0.328	ENST00000256545.4	EMC7	ER membrane protein complex subunit 7
chr17_-_79827808	0.327	ENST00000580685.1	ARHGDIA	Rho GDP dissociation inhibitor (GDI) alpha
chr14_+_23564700	0.324	ENST00000554203.1	C14orf119	chromosome 14 open reading frame 119
chr14_-_53417732	0.324	ENST00000399304.3 ENST00000395631.2 ENST00000341590.3 ENST00000343279.4	FERMT2	fermitin family member 2
chr9_-_117853297	0.322	ENST00000542877.1 ENST00000537320.1 ENST00000341037.4	TNC	tenascin C
chr9_+_35673853	0.320	ENST00000378357.4	CA9	carbonic anhydrase IX
chr1_+_145209092	0.316	ENST00000362074.6 ENST00000344859.3	NOTCH2NL	notch 2 N-terminal like
chr7_-_27224795	0.314	ENST00000006015.3	HOXA11	homeobox A11
chr2_+_89999259	0.314	ENST00000558026.1	IGKV2D-28	immunoglobulin kappa variable 2D-28
chr8_+_145086574	0.313	ENST00000377470.3 ENST00000447830.2	SPATC1	spermatogenesis and centriole associated 1
chr6_-_138820624	0.311	ENST00000343505.5	NHSL1	NHS-like 1
chr4_-_146859623	0.307	ENST00000379448.4 ENST00000513320.1	ZNF827	zinc finger protein 827
chr1_-_43205811	0.307	ENST00000372539.3 ENST00000296387.1 ENST00000539749.1	CLDN19	claudin 19
chr7_-_27224842	0.305	ENST00000517402.1	HOXA11	homeobox A11
chr1_+_178694300	0.304	ENST00000367635.3	RALGPS2	Ral GEF with PH domain and SH3 binding motif 2
chr12_-_109125285	0.303	ENST00000552871.1 ENST00000261401.3	CORO1C	coronin, actin binding protein, 1C
chrX_-_30877837	0.298	ENST00000378930.3	TAB3	TGF-beta activated kinase 1/MAP3K7 binding protein 3
chr15_-_34394008	0.298	ENST00000527822.1 ENST00000528949.1	EMC7	ER membrane protein complex subunit 7
chr1_+_153600869	0.295	ENST00000292169.1 ENST00000368696.3 ENST00000436839.1	S100A1	S100 calcium binding protein A1
chr7_+_100273736	0.294	ENST00000412215.1 ENST00000393924.1	GNB2	guanine nucleotide binding protein (G protein), beta polypeptide 2
chr19_-_41220957	0.293	ENST00000596357.1 ENST00000243583.6 ENST00000600080.1 ENST00000595254.1 ENST00000601967.1	ADCK4	aarF domain containing kinase 4
chr3_+_193853927	0.292	ENST00000232424.3	HES1	hes family bHLH transcription factor 1
chr3_+_130569429	0.291	ENST00000505330.1 ENST00000504381.1 ENST00000507488.2 ENST00000393221.4	ATP2C1	ATPase, Ca++ transporting, type 2C, member 1
chr11_-_117186946	0.291	ENST00000313005.6 ENST00000528053.1	BACE1	beta-site APP-cleaving enzyme 1
chr5_+_52776449	0.289	ENST00000396947.3	FST	follistatin
chr17_+_57784826	0.288	ENST00000262291.4	VMP1	vacuole membrane protein 1
chr9_-_114557207	0.288	ENST00000374287.3 ENST00000374283.5	C9orf84	chromosome 9 open reading frame 84

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.0	2.9	GO:0045658	regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
1.0	2.9	GO:0070634	transepithelial ammonium transport(GO:0070634)
0.6	5.2	GO:0006452	translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.5	1.6	GO:0014724	regulation of twitch skeletal muscle contraction(GO:0014724) fast-twitch skeletal muscle fiber contraction(GO:0031443) relaxation of skeletal muscle(GO:0090076)
0.4	2.2	GO:0071279	cellular response to cobalt ion(GO:0071279)
0.4	4.7	GO:0019227	neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.4	1.1	GO:0035623	regulation of pronephros size(GO:0035565) renal glucose absorption(GO:0035623)
0.3	1.3	GO:1902162	mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.2	0.6	GO:0015680	intracellular copper ion transport(GO:0015680)
0.2	1.4	GO:0061370	testosterone biosynthetic process(GO:0061370)
0.2	0.9	GO:0014835	myoblast differentiation involved in skeletal muscle regeneration(GO:0014835)
0.2	1.0	GO:0061343	cell adhesion involved in heart morphogenesis(GO:0061343)
0.2	2.9	GO:0042340	keratan sulfate catabolic process(GO:0042340)
0.2	0.8	GO:0010637	negative regulation of mitochondrial fusion(GO:0010637)
0.2	0.5	GO:0045226	extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.2	1.2	GO:0051549	positive regulation of keratinocyte migration(GO:0051549)
0.1	0.6	GO:0019470	4-hydroxyproline catabolic process(GO:0019470)
0.1	3.4	GO:0001502	cartilage condensation(GO:0001502)
0.1	0.8	GO:0032468	Golgi calcium ion homeostasis(GO:0032468)
0.1	0.5	GO:0090107	regulation of high-density lipoprotein particle assembly(GO:0090107)
0.1	0.4	GO:0006532	aspartate biosynthetic process(GO:0006532)
0.1	0.6	GO:0035426	extracellular matrix-cell signaling(GO:0035426)
0.1	0.4	GO:0060061	Spemann organizer formation(GO:0060061)
0.1	1.7	GO:0015816	glycine transport(GO:0015816)
0.1	2.8	GO:0006743	ubiquinone metabolic process(GO:0006743)
0.1	0.5	GO:0048496	maintenance of organ identity(GO:0048496)
0.1	0.3	GO:2000974	trochlear nerve development(GO:0021558) ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910) auditory receptor cell fate determination(GO:0042668) negative regulation of auditory receptor cell differentiation(GO:0045608) negative regulation of pro-B cell differentiation(GO:2000974)
0.1	0.4	GO:0002268	follicular dendritic cell differentiation(GO:0002268)
0.1	0.7	GO:0031914	negative regulation of synaptic plasticity(GO:0031914)
0.1	0.3	GO:0060447	bud outgrowth involved in lung branching(GO:0060447)
0.1	0.5	GO:0051012	microtubule sliding(GO:0051012)
0.1	0.8	GO:0070973	protein localization to endoplasmic reticulum exit site(GO:0070973)
0.1	0.7	GO:0070315	G1 to G0 transition involved in cell differentiation(GO:0070315)
0.1	0.4	GO:1903336	negative regulation of vacuolar transport(GO:1903336)
0.1	0.8	GO:0060753	regulation of mast cell chemotaxis(GO:0060753)
0.1	0.8	GO:0006600	creatine metabolic process(GO:0006600)
0.1	1.1	GO:0038003	opioid receptor signaling pathway(GO:0038003)
0.1	0.6	GO:0038028	insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.1	0.4	GO:0014028	notochord formation(GO:0014028)
0.1	0.4	GO:0031339	negative regulation of vesicle fusion(GO:0031339)
0.1	0.9	GO:0048172	regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.1	0.8	GO:0098887	neurotransmitter receptor transport, endosome to postsynaptic membrane(GO:0098887) neurotransmitter receptor transport, endosome to plasma membrane(GO:0099639)
0.1	0.2	GO:0043311	positive regulation of eosinophil degranulation(GO:0043311) positive regulation of eosinophil activation(GO:1902568)
0.1	0.9	GO:0036159	inner dynein arm assembly(GO:0036159)
0.1	0.1	GO:0031860	telomeric 3' overhang formation(GO:0031860)
0.1	0.2	GO:0010725	regulation of primitive erythrocyte differentiation(GO:0010725) eosinophil fate commitment(GO:0035854)
0.1	0.6	GO:0022417	protein maturation by protein folding(GO:0022417)
0.1	0.8	GO:0051798	positive regulation of hair follicle development(GO:0051798)
0.1	0.8	GO:0060346	bone trabecula formation(GO:0060346)
0.1	1.0	GO:0010867	positive regulation of triglyceride biosynthetic process(GO:0010867)
0.1	0.2	GO:0060947	negative regulation of transforming growth factor beta1 production(GO:0032911) cardiac vascular smooth muscle cell differentiation(GO:0060947)
0.1	0.7	GO:0031580	membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0	0.8	GO:0047484	regulation of response to osmotic stress(GO:0047484)
0.0	1.3	GO:0001522	pseudouridine synthesis(GO:0001522)
0.0	0.6	GO:0097264	self proteolysis(GO:0097264)
0.0	0.1	GO:0006114	glycerol biosynthetic process(GO:0006114)
0.0	0.5	GO:0021999	neural plate anterior/posterior regionalization(GO:0021999)
0.0	0.4	GO:0007256	activation of JNKK activity(GO:0007256)
0.0	1.0	GO:0045116	protein neddylation(GO:0045116)
0.0	0.4	GO:0034351	regulation of glial cell apoptotic process(GO:0034350) negative regulation of glial cell apoptotic process(GO:0034351)
0.0	0.5	GO:0019532	oxalate transport(GO:0019532)
0.0	0.6	GO:0043320	natural killer cell degranulation(GO:0043320)
0.0	0.6	GO:0014041	regulation of neuron maturation(GO:0014041)
0.0	0.4	GO:0051694	pointed-end actin filament capping(GO:0051694)
0.0	0.2	GO:0043983	histone H4-K12 acetylation(GO:0043983)
0.0	0.8	GO:2000052	positive regulation of non-canonical Wnt signaling pathway(GO:2000052)
0.0	0.4	GO:0048733	sebaceous gland development(GO:0048733)
0.0	0.4	GO:0045039	protein import into mitochondrial inner membrane(GO:0045039)
0.0	0.6	GO:0033623	regulation of integrin activation(GO:0033623)
0.0	0.6	GO:0060272	embryonic skeletal joint morphogenesis(GO:0060272)
0.0	0.2	GO:1990637	response to prolactin(GO:1990637)
0.0	0.2	GO:0032328	alanine transport(GO:0032328)
0.0	0.1	GO:0046449	creatinine metabolic process(GO:0046449)
0.0	0.5	GO:0060088	detection of mechanical stimulus involved in sensory perception of sound(GO:0050910) auditory receptor cell stereocilium organization(GO:0060088)
0.0	0.4	GO:0097396	response to interleukin-17(GO:0097396) cellular response to interleukin-17(GO:0097398)
0.0	0.1	GO:2000861	estrogen secretion(GO:0035937) estradiol secretion(GO:0035938) regulation of estrogen secretion(GO:2000861) regulation of estradiol secretion(GO:2000864)
0.0	0.1	GO:0060454	detection of temperature stimulus involved in thermoception(GO:0050960) positive regulation of gastric acid secretion(GO:0060454) response to capsazepine(GO:1901594)
0.0	0.2	GO:0016480	negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.0	0.7	GO:0003215	cardiac right ventricle morphogenesis(GO:0003215)
0.0	0.1	GO:0030047	actin modification(GO:0030047)
0.0	0.2	GO:0061086	negative regulation of histone H3-K27 methylation(GO:0061086)
0.0	1.3	GO:0000188	inactivation of MAPK activity(GO:0000188)
0.0	0.3	GO:0044387	negative regulation of protein kinase activity by regulation of protein phosphorylation(GO:0044387)
0.0	0.4	GO:2000210	positive regulation of anoikis(GO:2000210)
0.0	1.0	GO:0031954	positive regulation of protein autophosphorylation(GO:0031954)
0.0	0.3	GO:0030091	protein repair(GO:0030091)
0.0	0.1	GO:0035616	histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.0	0.7	GO:0050908	detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0	0.2	GO:0043461	proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.0	0.7	GO:0090023	positive regulation of neutrophil chemotaxis(GO:0090023)
0.0	0.3	GO:0097475	motor neuron migration(GO:0097475)
0.0	0.2	GO:0061314	Notch signaling involved in heart development(GO:0061314)
0.0	0.1	GO:1904322	response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.0	0.1	GO:0003150	muscular septum morphogenesis(GO:0003150)
0.0	0.1	GO:0033512	L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512)
0.0	0.3	GO:1901387	positive regulation of voltage-gated calcium channel activity(GO:1901387)
0.0	0.2	GO:2001300	lipoxin metabolic process(GO:2001300)
0.0	0.4	GO:0090168	Golgi reassembly(GO:0090168)
0.0	0.3	GO:0033622	integrin activation(GO:0033622)
0.0	0.2	GO:0030202	heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.0	0.7	GO:0006833	water transport(GO:0006833)
0.0	0.2	GO:0075525	viral translational termination-reinitiation(GO:0075525)
0.0	0.1	GO:0090283	regulation of protein glycosylation in Golgi(GO:0090283)
0.0	0.2	GO:0017196	N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0	1.3	GO:0035904	aorta development(GO:0035904)
0.0	0.2	GO:0046598	positive regulation of viral entry into host cell(GO:0046598)
0.0	0.1	GO:0061364	chemorepulsion involved in embryonic olfactory bulb interneuron precursor migration(GO:0021834) apoptotic process involved in luteolysis(GO:0061364)
0.0	0.2	GO:0032020	ISG15-protein conjugation(GO:0032020)
0.0	0.1	GO:1901804	beta-glucoside metabolic process(GO:1901804) beta-glucoside catabolic process(GO:1901805) positive regulation of neuronal action potential(GO:1904457)
0.0	0.2	GO:0061734	parkin-mediated mitophagy in response to mitochondrial depolarization(GO:0061734)
0.0	0.1	GO:0001302	replicative cell aging(GO:0001302)
0.0	0.1	GO:0033484	nitric oxide homeostasis(GO:0033484)
0.0	0.1	GO:0006369	termination of RNA polymerase II transcription(GO:0006369)
0.0	0.3	GO:0010603	regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.0	0.4	GO:0046341	CDP-diacylglycerol metabolic process(GO:0046341)
0.0	0.1	GO:0090649	response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
0.0	0.1	GO:0007197	adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.0	0.1	GO:0048743	positive regulation of skeletal muscle fiber development(GO:0048743)
0.0	0.2	GO:0015747	urate transport(GO:0015747)
0.0	0.6	GO:0009435	NAD biosynthetic process(GO:0009435)
0.0	2.9	GO:0031424	keratinization(GO:0031424)
0.0	0.5	GO:0030252	growth hormone secretion(GO:0030252)
0.0	0.4	GO:0042753	positive regulation of circadian rhythm(GO:0042753)
0.0	0.1	GO:0070120	ciliary neurotrophic factor-mediated signaling pathway(GO:0070120)
0.0	0.2	GO:0042118	endothelial cell activation(GO:0042118)
0.0	0.4	GO:0006957	complement activation, alternative pathway(GO:0006957)
0.0	0.5	GO:0040018	positive regulation of multicellular organism growth(GO:0040018)
0.0	0.1	GO:0016554	cytidine to uridine editing(GO:0016554)
0.0	0.1	GO:1902723	negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
0.0	0.1	GO:0042797	5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
0.0	0.5	GO:0001755	neural crest cell migration(GO:0001755)
0.0	0.1	GO:0030263	apoptotic chromosome condensation(GO:0030263)
0.0	0.2	GO:0071313	cellular response to caffeine(GO:0071313)
0.0	0.2	GO:0070914	UV-damage excision repair(GO:0070914)
0.0	0.8	GO:2000273	positive regulation of receptor activity(GO:2000273)
0.0	0.3	GO:0030150	protein import into mitochondrial matrix(GO:0030150)
0.0	0.2	GO:0032802	low-density lipoprotein particle receptor catabolic process(GO:0032802)
0.0	0.1	GO:0016240	autophagosome docking(GO:0016240)
0.0	2.4	GO:0007173	epidermal growth factor receptor signaling pathway(GO:0007173)
0.0	0.2	GO:0016998	cell wall macromolecule catabolic process(GO:0016998)
0.0	0.0	GO:1903225	tendon development(GO:0035989) regulation of endodermal cell differentiation(GO:1903224) negative regulation of endodermal cell differentiation(GO:1903225)
0.0	0.1	GO:0030324	respiratory tube development(GO:0030323) lung development(GO:0030324)
0.0	0.4	GO:0006882	cellular zinc ion homeostasis(GO:0006882)
0.0	0.7	GO:0071377	cellular response to glucagon stimulus(GO:0071377)
0.0	0.2	GO:0030212	hyaluronan metabolic process(GO:0030212)
0.0	0.3	GO:0071526	semaphorin-plexin signaling pathway(GO:0071526)
0.0	0.6	GO:0014003	oligodendrocyte development(GO:0014003)
0.0	0.1	GO:0046836	glycolipid transport(GO:0046836)
0.0	0.3	GO:2000637	positive regulation of gene silencing by miRNA(GO:2000637)
0.0	0.0	GO:0045647	negative regulation of erythrocyte differentiation(GO:0045647)
0.0	0.2	GO:1902187	negative regulation of viral release from host cell(GO:1902187)
0.0	0.2	GO:0034498	early endosome to Golgi transport(GO:0034498)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	4.5	GO:0005642	annulate lamellae(GO:0005642)
0.2	1.0	GO:0071595	Nem1-Spo7 phosphatase complex(GO:0071595)
0.2	0.9	GO:0036156	inner dynein arm(GO:0036156)
0.2	0.5	GO:0002139	stereocilia coupling link(GO:0002139)
0.2	2.2	GO:0043203	axon hillock(GO:0043203)
0.1	0.9	GO:0071541	eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.1	0.4	GO:0033257	Bcl3/NF-kappaB2 complex(GO:0033257)
0.1	0.4	GO:0042721	mitochondrial inner membrane protein insertion complex(GO:0042721)
0.1	0.8	GO:0098845	postsynaptic endosome(GO:0098845)
0.1	1.6	GO:0031095	platelet dense tubular network membrane(GO:0031095)
0.1	0.3	GO:0043625	delta DNA polymerase complex(GO:0043625)
0.1	0.6	GO:0005851	eukaryotic translation initiation factor 2B complex(GO:0005851)
0.1	0.6	GO:0001739	sex chromatin(GO:0001739)
0.1	0.2	GO:0016222	procollagen-proline 4-dioxygenase complex(GO:0016222)
0.1	0.3	GO:1990425	ryanodine receptor complex(GO:1990425)
0.1	0.1	GO:0014802	terminal cisterna(GO:0014802)
0.0	2.5	GO:0033017	sarcoplasmic reticulum membrane(GO:0033017)
0.0	0.6	GO:0033093	Weibel-Palade body(GO:0033093)
0.0	0.6	GO:0072546	ER membrane protein complex(GO:0072546)
0.0	0.5	GO:0032426	stereocilium tip(GO:0032426)
0.0	0.1	GO:0097059	CNTFR-CLCF1 complex(GO:0097059)
0.0	0.2	GO:0031417	NatC complex(GO:0031417)
0.0	1.0	GO:0030014	CCR4-NOT complex(GO:0030014)
0.0	0.3	GO:0031467	Cul7-RING ubiquitin ligase complex(GO:0031467)
0.0	0.2	GO:0000110	nucleotide-excision repair factor 1 complex(GO:0000110)
0.0	0.1	GO:0030895	apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.0	0.3	GO:0042567	insulin-like growth factor ternary complex(GO:0042567)
0.0	1.0	GO:0005640	nuclear outer membrane(GO:0005640)
0.0	0.2	GO:0030905	retromer, tubulation complex(GO:0030905)
0.0	0.2	GO:0033018	sarcoplasmic reticulum lumen(GO:0033018)
0.0	0.1	GO:0032279	asymmetric synapse(GO:0032279)
0.0	0.6	GO:0005614	interstitial matrix(GO:0005614)
0.0	0.3	GO:0016600	flotillin complex(GO:0016600)
0.0	0.8	GO:0032839	dendrite cytoplasm(GO:0032839)
0.0	0.2	GO:0097427	microtubule bundle(GO:0097427)
0.0	1.9	GO:0045095	keratin filament(GO:0045095)
0.0	2.1	GO:0034707	chloride channel complex(GO:0034707)
0.0	0.6	GO:0001891	phagocytic cup(GO:0001891)
0.0	3.1	GO:0043202	lysosomal lumen(GO:0043202)
0.0	1.2	GO:0045171	intercellular bridge(GO:0045171)
0.0	0.3	GO:0031528	microvillus membrane(GO:0031528)
0.0	0.2	GO:0000322	storage vacuole(GO:0000322)
0.0	0.3	GO:0005744	mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0	0.8	GO:0000407	pre-autophagosomal structure(GO:0000407)
0.0	0.2	GO:0098554	cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.0	0.9	GO:0031941	filamentous actin(GO:0031941)
0.0	0.2	GO:1990454	L-type voltage-gated calcium channel complex(GO:1990454)
0.0	2.8	GO:1904813	ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.0	0.2	GO:0032039	integrator complex(GO:0032039)
0.0	6.3	GO:0045121	membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0	0.3	GO:0016529	sarcoplasmic reticulum(GO:0016529)
0.0	0.1	GO:0000127	transcription factor TFIIIC complex(GO:0000127)
0.0	0.2	GO:0001673	male germ cell nucleus(GO:0001673)
0.0	1.5	GO:0005604	basement membrane(GO:0005604)
0.0	0.2	GO:0030008	TRAPP complex(GO:0030008)
0.0	0.2	GO:0033180	proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0	2.3	GO:0001650	fibrillar center(GO:0001650)
0.0	0.5	GO:0034364	high-density lipoprotein particle(GO:0034364)
0.0	0.2	GO:0030131	clathrin adaptor complex(GO:0030131)
0.0	0.2	GO:0030122	AP-2 adaptor complex(GO:0030122)
0.0	0.8	GO:0030670	phagocytic vesicle membrane(GO:0030670)
0.0	2.7	GO:0005741	mitochondrial outer membrane(GO:0005741) organelle outer membrane(GO:0031968)
0.0	0.1	GO:0042629	mast cell granule(GO:0042629)
0.0	0.6	GO:0044291	cell-cell contact zone(GO:0044291)
0.0	3.7	GO:0016324	apical plasma membrane(GO:0016324)
0.0	0.1	GO:0061574	ASAP complex(GO:0061574)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.7	3.3	GO:0005219	ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.5	2.9	GO:0016314	phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.2	1.4	GO:0047045	testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.2	4.5	GO:0017070	U6 snRNA binding(GO:0017070)
0.2	2.1	GO:0015187	glycine transmembrane transporter activity(GO:0015187)
0.2	2.5	GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.2	0.6	GO:0016532	superoxide dismutase copper chaperone activity(GO:0016532)
0.1	0.5	GO:0034186	apolipoprotein A-I binding(GO:0034186)
0.1	0.4	GO:0004069	L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069)
0.1	0.4	GO:0003881	CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity(GO:0003881)
0.1	0.5	GO:0050501	hyaluronan synthase activity(GO:0050501)
0.1	1.0	GO:0071532	ankyrin repeat binding(GO:0071532)
0.1	0.4	GO:0004706	JUN kinase kinase kinase activity(GO:0004706)
0.1	0.8	GO:0015277	kainate selective glutamate receptor activity(GO:0015277)
0.1	0.3	GO:0008798	beta-aspartyl-peptidase activity(GO:0008798)
0.1	2.9	GO:0005540	hyaluronic acid binding(GO:0005540)
0.1	3.0	GO:0030506	ankyrin binding(GO:0030506)
0.1	0.8	GO:0032051	clathrin light chain binding(GO:0032051)
0.1	1.1	GO:0004985	opioid receptor activity(GO:0004985)
0.1	0.4	GO:0004699	calcium-independent protein kinase C activity(GO:0004699)
0.1	1.3	GO:0009982	pseudouridine synthase activity(GO:0009982)
0.1	2.4	GO:0005388	calcium-transporting ATPase activity(GO:0005388)
0.1	0.4	GO:0019828	aspartic-type endopeptidase inhibitor activity(GO:0019828)
0.1	1.1	GO:0045499	chemorepellent activity(GO:0045499)
0.1	0.4	GO:0004045	aminoacyl-tRNA hydrolase activity(GO:0004045)
0.1	0.9	GO:0048273	mitogen-activated protein kinase p38 binding(GO:0048273)
0.1	1.1	GO:0048185	activin binding(GO:0048185)
0.1	0.2	GO:0005539	glycosaminoglycan binding(GO:0005539)
0.1	0.9	GO:0045236	CXCR chemokine receptor binding(GO:0045236)
0.1	0.3	GO:0004719	protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.1	0.6	GO:0015266	protein channel activity(GO:0015266)
0.1	1.1	GO:0005229	intracellular calcium activated chloride channel activity(GO:0005229)
0.1	1.1	GO:0008253	5'-nucleotidase activity(GO:0008253)
0.1	1.6	GO:0071949	FAD binding(GO:0071949)
0.0	0.2	GO:0016230	sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.0	0.5	GO:0019531	oxalate transmembrane transporter activity(GO:0019531)
0.0	0.4	GO:0030368	interleukin-17 receptor activity(GO:0030368)
0.0	0.8	GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.0	0.7	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.0	1.1	GO:0005247	voltage-gated chloride channel activity(GO:0005247)
0.0	0.7	GO:0015250	water channel activity(GO:0015250)
0.0	0.2	GO:0015016	[heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0	0.6	GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.0	0.9	GO:0008569	ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0	0.9	GO:0004745	retinol dehydrogenase activity(GO:0004745)
0.0	0.2	GO:0004991	parathyroid hormone receptor activity(GO:0004991)
0.0	0.9	GO:0035259	glucocorticoid receptor binding(GO:0035259)
0.0	0.1	GO:0001003	polymerase III regulatory region sequence-specific DNA binding(GO:0000992) RNA polymerase III type 1 promoter sequence-specific DNA binding(GO:0001002) RNA polymerase III type 2 promoter sequence-specific DNA binding(GO:0001003)
0.0	0.5	GO:0030280	structural constituent of epidermis(GO:0030280)
0.0	0.8	GO:0070402	NADPH binding(GO:0070402)
0.0	0.2	GO:0004656	procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.0	0.8	GO:0097602	cullin family protein binding(GO:0097602)
0.0	0.2	GO:1990460	leptin receptor binding(GO:1990460)
0.0	0.3	GO:0045545	syndecan binding(GO:0045545)
0.0	0.2	GO:0000285	1-phosphatidylinositol-3-phosphate 5-kinase activity(GO:0000285)
0.0	0.4	GO:0099602	acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.0	0.1	GO:0004566	beta-glucuronidase activity(GO:0004566)
0.0	4.1	GO:0004222	metalloendopeptidase activity(GO:0004222)
0.0	0.7	GO:0003746	translation elongation factor activity(GO:0003746)
0.0	0.1	GO:0098519	nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.0	0.8	GO:0051184	cofactor transporter activity(GO:0051184)
0.0	0.6	GO:0031005	filamin binding(GO:0031005)
0.0	0.3	GO:0005094	Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0	0.1	GO:0004594	pantothenate kinase activity(GO:0004594)
0.0	0.2	GO:0042296	ISG15 transferase activity(GO:0042296)
0.0	0.2	GO:0038049	transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049)
0.0	1.0	GO:0017091	AU-rich element binding(GO:0017091)
0.0	0.4	GO:0032036	myosin heavy chain binding(GO:0032036)
0.0	0.1	GO:0016748	succinyltransferase activity(GO:0016748)
0.0	0.6	GO:0004029	aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.0	0.2	GO:0019788	NEDD8 transferase activity(GO:0019788)
0.0	0.2	GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0	0.6	GO:0001965	G-protein alpha-subunit binding(GO:0001965)
0.0	0.2	GO:0008379	thioredoxin peroxidase activity(GO:0008379)
0.0	0.2	GO:0000990	transcription factor activity, core RNA polymerase binding(GO:0000990)
0.0	2.0	GO:0003730	mRNA 3'-UTR binding(GO:0003730)
0.0	0.7	GO:0019956	chemokine binding(GO:0019956)
0.0	0.4	GO:0047617	acyl-CoA hydrolase activity(GO:0047617)
0.0	0.1	GO:0004897	ciliary neurotrophic factor receptor activity(GO:0004897)
0.0	0.2	GO:0001849	complement component C1q binding(GO:0001849)
0.0	0.5	GO:0042813	Wnt-activated receptor activity(GO:0042813)
0.0	0.1	GO:0046974	histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0	0.1	GO:0034648	histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.0	0.1	GO:0001537	N-acetylgalactosamine 4-O-sulfotransferase activity(GO:0001537)
0.0	0.1	GO:0016907	G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0	1.4	GO:0003743	translation initiation factor activity(GO:0003743)
0.0	1.1	GO:0004864	protein phosphatase inhibitor activity(GO:0004864)
0.0	2.1	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.0	0.0	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0	0.1	GO:0043237	laminin-1 binding(GO:0043237)
0.0	0.1	GO:0048495	Roundabout binding(GO:0048495)
0.0	0.1	GO:0004348	glucosylceramidase activity(GO:0004348)
0.0	0.3	GO:0044548	S100 protein binding(GO:0044548)
0.0	0.6	GO:0005159	insulin-like growth factor receptor binding(GO:0005159)
0.0	0.2	GO:0015143	urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0	0.1	GO:0097603	temperature-gated ion channel activity(GO:0097603)
0.0	0.1	GO:0045159	myosin II binding(GO:0045159)
0.0	0.4	GO:0005523	tropomyosin binding(GO:0005523)
0.0	0.2	GO:0004089	carbonate dehydratase activity(GO:0004089)
0.0	0.1	GO:0008454	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0	0.2	GO:0035615	clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0	0.4	GO:0001848	complement binding(GO:0001848)
0.0	0.4	GO:0005109	frizzled binding(GO:0005109)
0.0	0.2	GO:0009931	calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0	0.4	GO:0005385	zinc ion transmembrane transporter activity(GO:0005385)
0.0	0.2	GO:0003796	lysozyme activity(GO:0003796)
0.0	0.8	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0	0.7	GO:0048365	Rac GTPase binding(GO:0048365)
0.0	1.5	GO:0005089	Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0	0.2	GO:0004596	peptide alpha-N-acetyltransferase activity(GO:0004596)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.9	ST_INTERLEUKIN_4_PATHWAY	Interleukin 4 (IL-4) Pathway
0.0	1.9	PID_EPHRINB_REV_PATHWAY	Ephrin B reverse signaling
0.0	1.2	PID_BETA_CATENIN_DEG_PATHWAY	Degradation of beta catenin
0.0	1.7	PID_SYNDECAN_4_PATHWAY	Syndecan-4-mediated signaling events
0.0	0.9	PID_LYMPH_ANGIOGENESIS_PATHWAY	VEGFR3 signaling in lymphatic endothelium
0.0	6.7	NABA_ECM_REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0	1.1	NABA_BASEMENT_MEMBRANES	Genes encoding structural components of basement membranes
0.0	1.1	NABA_PROTEOGLYCANS	Genes encoding proteoglycans
0.0	0.4	ST_G_ALPHA_S_PATHWAY	G alpha s Pathway
0.0	0.3	PID_ALK2_PATHWAY	ALK2 signaling events
0.0	0.7	PID_RAS_PATHWAY	Regulation of Ras family activation
0.0	0.8	PID_BMP_PATHWAY	BMP receptor signaling
0.0	0.4	PID_INSULIN_GLUCOSE_PATHWAY	Insulin-mediated glucose transport
0.0	0.2	PID_AR_NONGENOMIC_PATHWAY	Nongenotropic Androgen signaling
0.0	0.4	PID_IFNG_PATHWAY	IFN-gamma pathway
0.0	0.9	PID_P53_REGULATION_PATHWAY	p53 pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	2.9	REACTOME_KERATAN_SULFATE_DEGRADATION	Genes involved in Keratan sulfate degradation
0.2	3.8	REACTOME_HDL_MEDIATED_LIPID_TRANSPORT	Genes involved in HDL-mediated lipid transport
0.1	4.3	REACTOME_PTM_GAMMA_CARBOXYLATION_HYPUSINE_FORMATION_AND_ARYLSULFATASE_ACTIVATION	Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.1	1.4	REACTOME_ANDROGEN_BIOSYNTHESIS	Genes involved in Androgen biosynthesis
0.1	1.7	REACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.1	2.2	REACTOME_AMINE_COMPOUND_SLC_TRANSPORTERS	Genes involved in Amine compound SLC transporters
0.0	2.0	REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.0	0.7	REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS	Genes involved in Passive Transport by Aquaporins
0.0	0.9	REACTOME_ACTIVATION_OF_THE_AP1_FAMILY_OF_TRANSCRIPTION_FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.0	2.9	REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT	Genes involved in Mitochondrial Protein Import
0.0	1.2	REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX	Genes involved in Degradation of the extracellular matrix
0.0	1.1	REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS	Genes involved in Regulation of gene expression in beta cells
0.0	0.8	REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	0.8	REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.0	0.8	REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.0	0.5	REACTOME_HYALURONAN_METABOLISM	Genes involved in Hyaluronan metabolism
0.0	0.8	REACTOME_CHOLESTEROL_BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.0	0.7	REACTOME_ADP_SIGNALLING_THROUGH_P2RY12	Genes involved in ADP signalling through P2Y purinoceptor 12
0.0	0.3	REACTOME_REMOVAL_OF_THE_FLAP_INTERMEDIATE_FROM_THE_C_STRAND	Genes involved in Removal of the Flap Intermediate from the C-strand
0.0	0.3	REACTOME_IRAK2_MEDIATED_ACTIVATION_OF_TAK1_COMPLEX_UPON_TLR7_8_OR_9_STIMULATION	Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0	0.2	REACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT	Genes involved in Regulation of beta-cell development
0.0	0.9	REACTOME_DEADENYLATION_OF_MRNA	Genes involved in Deadenylation of mRNA
0.0	0.8	REACTOME_SEMA4D_INDUCED_CELL_MIGRATION_AND_GROWTH_CONE_COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0	0.4	REACTOME_ACTIVATION_OF_RAC	Genes involved in Activation of Rac
0.0	0.9	REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES	Genes involved in Ion transport by P-type ATPases
0.0	0.4	REACTOME_ZINC_TRANSPORTERS	Genes involved in Zinc transporters
0.0	0.4	REACTOME_DESTABILIZATION_OF_MRNA_BY_KSRP	Genes involved in Destabilization of mRNA by KSRP
0.0	0.4	REACTOME_INITIAL_TRIGGERING_OF_COMPLEMENT	Genes involved in Initial triggering of complement
0.0	0.3	REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0	0.2	REACTOME_REVERSIBLE_HYDRATION_OF_CARBON_DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.0	1.5	REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS	Genes involved in Class B/2 (Secretin family receptors)
0.0	0.7	REACTOME_PACKAGING_OF_TELOMERE_ENDS	Genes involved in Packaging Of Telomere Ends
0.0	0.7	REACTOME_NETRIN1_SIGNALING	Genes involved in Netrin-1 signaling
0.0	0.2	REACTOME_CHYLOMICRON_MEDIATED_LIPID_TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.0	0.4	REACTOME_G_ALPHA_Z_SIGNALLING_EVENTS	Genes involved in G alpha (z) signalling events
0.0	0.4	REACTOME_RIP_MEDIATED_NFKB_ACTIVATION_VIA_DAI	Genes involved in RIP-mediated NFkB activation via DAI
0.0	0.4	REACTOME_HS_GAG_BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.0	0.7	REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.0	0.2	REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_ATF6_ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0	0.2	REACTOME_HORMONE_LIGAND_BINDING_RECEPTORS	Genes involved in Hormone ligand-binding receptors
0.0	0.8	REACTOME_FORMATION_OF_THE_TERNARY_COMPLEX_AND_SUBSEQUENTLY_THE_43S_COMPLEX	Genes involved in Formation of the ternary complex, and subsequently, the 43S complex

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