Motif ID: KLF13

Z-value: 0.570


Transcription factors associated with KLF13:

Gene SymbolEntrez IDGene Name
KLF13 ENSG00000169926.5 KLF13

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
KLF13hg19_v2_chr15_+_31658349_316583580.135.4e-01Click!


Activity profile for motif KLF13.

activity profile for motif KLF13


Sorted Z-values histogram for motif KLF13

Sorted Z-values for motif KLF13



Network of associatons between targets according to the STRING database.



First level regulatory network of KLF13

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_-_31697977 0.874 ENST00000375787.2
 DDAH2
dimethylarginine dimethylaminohydrolase 2
chr6_-_31697563 0.860 ENST00000375789.2
ENST00000416410.1
 DDAH2

dimethylarginine dimethylaminohydrolase 2

chr15_+_30375158 0.836 ENST00000341650.6
ENST00000567927.1
 GOLGA8J

golgin A8 family, member J

chr15_+_30896329 0.807 ENST00000566740.1
 GOLGA8H
golgin A8 family, member H
chr3_-_138048682 0.448 ENST00000383180.2
 NME9
NME/NM23 family member 9
chr15_-_32695396 0.409 ENST00000435655.2
ENST00000512626.2
 AC139426.2
GOLGA8K
Uncharacterized protein; cDNA FLJ52611
golgin A8 family, member K
chr17_-_17109579 0.400 ENST00000321560.3
 PLD6
phospholipase D family, member 6
chr22_-_41985865 0.389 ENST00000216259.7
 PMM1
phosphomannomutase 1
chr6_-_31697255 0.356 ENST00000436437.1
 DDAH2
dimethylarginine dimethylaminohydrolase 2
chr19_-_50311896 0.347 ENST00000529634.2
 FUZ
fuzzy planar cell polarity protein
chr19_+_1071203 0.341 ENST00000543365.1
 HMHA1
histocompatibility (minor) HA-1
chr6_-_31125850 0.314 ENST00000507751.1
ENST00000448162.2
ENST00000502557.1
ENST00000503420.1
ENST00000507892.1
ENST00000507226.1
ENST00000513222.1
ENST00000503934.1
ENST00000396263.2
ENST00000508683.1
ENST00000428174.1
ENST00000448141.2
ENST00000507829.1
ENST00000455279.2
ENST00000376266.5
 CCHCR1














coiled-coil alpha-helical rod protein 1














chr15_-_75017711 0.311 ENST00000567032.1
ENST00000564596.1
ENST00000566503.1
ENST00000395049.4
ENST00000395048.2
ENST00000379727.3
 CYP1A1





cytochrome P450, family 1, subfamily A, polypeptide 1





chr17_-_40333150 0.299 ENST00000264661.3
 KCNH4
potassium voltage-gated channel, subfamily H (eag-related), member 4
chr1_+_39546988 0.290 ENST00000484793.1
 MACF1
microtubule-actin crosslinking factor 1
chr3_+_50606901 0.286 ENST00000455834.1
 HEMK1
HemK methyltransferase family member 1
chr21_+_45905448 0.283 ENST00000449713.1
 AP001065.15
AP001065.15
chr17_+_7184986 0.274 ENST00000317370.8
ENST00000571308.1
 SLC2A4

solute carrier family 2 (facilitated glucose transporter), member 4

chr1_+_39547082 0.269 ENST00000602421.1
 MACF1
microtubule-actin crosslinking factor 1
chr8_-_37756972 0.263 ENST00000330843.4
ENST00000522727.1
ENST00000287263.4
 RAB11FIP1


RAB11 family interacting protein 1 (class I)



Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 43 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.1 GO:0006527 arginine catabolic process(GO:0006527)
0.1 0.8 GO:0045007 depurination(GO:0045007)
0.0 0.6 GO:0043001 Golgi to plasma membrane protein transport(GO:0043001)
0.1 0.5 GO:0006210 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.1 0.4 GO:0043095 regulation of GTP cyclohydrolase I activity(GO:0043095) negative regulation of GTP cyclohydrolase I activity(GO:0043105)
0.1 0.4 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.0 0.4 GO:0010635 regulation of mitochondrial fusion(GO:0010635)
0.0 0.4 GO:0006228 UTP biosynthetic process(GO:0006228)
0.1 0.3 GO:0018894 dibenzo-p-dioxin metabolic process(GO:0018894) cellular alkene metabolic process(GO:0043449)
0.1 0.3 GO:0090299 regulation of neural crest formation(GO:0090299) negative regulation of neural crest formation(GO:0090301) negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314)
0.0 0.3 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.0 0.3 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.0 0.3 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.0 0.3 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.0 0.3 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.0 0.3 GO:0035493 SNARE complex assembly(GO:0035493)
0.0 0.3 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.1 0.2 GO:0071284 response to platinum ion(GO:0070541) cellular response to lead ion(GO:0071284)
0.0 0.2 GO:0046203 spermidine catabolic process(GO:0046203)
0.0 0.2 GO:0006203 dGTP catabolic process(GO:0006203)

Gene overrepresentation in cellular_component category:

Showing 1 to 11 of 11 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.3 GO:0030893 meiotic cohesin complex(GO:0030893)
0.0 0.3 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.3 GO:0033063 DNA recombinase mediator complex(GO:0033061) Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0 0.3 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.2 GO:0032798 Swi5-Sfr1 complex(GO:0032798)
0.0 0.2 GO:0070695 FHF complex(GO:0070695)
0.0 0.1 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.0 0.1 GO:0035189 Rb-E2F complex(GO:0035189)
0.0 0.1 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.0 0.1 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.1 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 25 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 2.1 GO:0016403 dimethylargininase activity(GO:0016403)
0.2 0.8 GO:0032408 MutLbeta complex binding(GO:0032406) MutSbeta complex binding(GO:0032408)
0.0 0.5 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.1 0.4 GO:0044549 GTP cyclohydrolase binding(GO:0044549)
0.0 0.4 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.0 0.4 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.1 0.3 GO:0070576 vitamin D 24-hydroxylase activity(GO:0070576)
0.0 0.3 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.0 0.3 GO:0000150 recombinase activity(GO:0000150)
0.0 0.3 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 0.3 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 0.2 GO:0034038 deoxyhypusine synthase activity(GO:0034038)
0.1 0.2 GO:0035539 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity(GO:0008413) 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity(GO:0035539)
0.0 0.2 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
0.0 0.2 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.0 0.1 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.0 0.1 GO:0030272 5-formyltetrahydrofolate cyclo-ligase activity(GO:0030272)
0.0 0.1 GO:0070404 NADH binding(GO:0070404)
0.0 0.1 GO:1902444 riboflavin binding(GO:1902444)
0.0 0.1 GO:0005483 soluble NSF attachment protein activity(GO:0005483)

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 9 of 9 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.8 REACTOME_BASE_FREE_SUGAR_PHOSPHATE_REMOVAL_VIA_THE_SINGLE_NUCLEOTIDE_REPLACEMENT_PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 0.5 REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.4 REACTOME_SYNTHESIS_OF_SUBSTRATES_IN_N_GLYCAN_BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.4 REACTOME_TETRAHYDROBIOPTERIN_BH4_SYNTHESIS_RECYCLING_SALVAGE_AND_REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.3 REACTOME_VITAMIN_B5_PANTOTHENATE_METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.3 REACTOME_XENOBIOTICS Genes involved in Xenobiotics
0.0 0.3 REACTOME_FACILITATIVE_NA_INDEPENDENT_GLUCOSE_TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.3 REACTOME_PROTEOLYTIC_CLEAVAGE_OF_SNARE_COMPLEX_PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.2 REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)