Motif ID: KLF7

Z-value: 0.182


Transcription factors associated with KLF7:

Gene SymbolEntrez IDGene Name
KLF7 ENSG00000118263.10 KLF7

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
KLF7hg19_v2_chr2_-_208031542_2080315950.106.5e-01Click!


Activity profile for motif KLF7.

activity profile for motif KLF7


Sorted Z-values histogram for motif KLF7

Sorted Z-values for motif KLF7



Network of associatons between targets according to the STRING database.



First level regulatory network of KLF7

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr3_+_186353756 0.356 ENST00000431018.1
ENST00000450521.1
ENST00000539949.1
 FETUB


fetuin B


chr16_+_31539197 0.135 ENST00000564707.1
 AHSP
alpha hemoglobin stabilizing protein
chr1_-_21948906 0.087 ENST00000374761.2
ENST00000599760.1
 RAP1GAP

RAP1 GTPase activating protein

chr19_+_39390320 0.073 ENST00000576510.1
 NFKBIB
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
chr8_-_6837602 0.070 ENST00000382692.2
 DEFA1
defensin, alpha 1
chr15_+_92937058 0.069 ENST00000268164.3
 ST8SIA2
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2
chr8_-_6875778 0.064 ENST00000327857.2
ENST00000535841.1
 DEFA3
DEFA1B
defensin, alpha 3, neutrophil-specific
defensin, alpha 1B
chr16_+_11439286 0.060 ENST00000312499.5
ENST00000576027.1
 RMI2

RecQ mediated genome instability 2

chr3_-_105587879 0.054 ENST00000264122.4
ENST00000403724.1
ENST00000405772.1
 CBLB


Cbl proto-oncogene B, E3 ubiquitin protein ligase


chr16_+_81772633 0.054 ENST00000565054.1
ENST00000566191.1
ENST00000565272.1
ENST00000563954.1
 PLCG2
RP11-960L18.1


phospholipase C, gamma 2 (phosphatidylinositol-specific)
RP11-960L18.1


chr8_+_17104539 0.043 ENST00000521829.1
ENST00000521005.1
 VPS37A

vacuolar protein sorting 37 homolog A (S. cerevisiae)

chr5_+_173315283 0.040 ENST00000265085.5
 CPEB4
cytoplasmic polyadenylation element binding protein 4
chr1_-_157108266 0.037 ENST00000326786.4
 ETV3
ets variant 3
chr2_-_74710078 0.035 ENST00000290418.4
 CCDC142
coiled-coil domain containing 142
chr1_-_19229248 0.034 ENST00000375341.3
 ALDH4A1
aldehyde dehydrogenase 4 family, member A1
chr19_+_39390587 0.034 ENST00000572515.1
ENST00000392079.3
ENST00000575359.1
ENST00000313582.5
 NFKBIB



nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta



chr6_-_30585009 0.032 ENST00000376511.2
 PPP1R10
protein phosphatase 1, regulatory subunit 10
chr3_-_178865747 0.031 ENST00000435560.1
 RP11-360P21.2
RP11-360P21.2
chr19_-_7694417 0.031 ENST00000358368.4
ENST00000534844.1
 XAB2

XPA binding protein 2

chr17_+_41476327 0.030 ENST00000320033.4
 ARL4D
ADP-ribosylation factor-like 4D
chr1_-_19229014 0.029 ENST00000538839.1
ENST00000290597.5
 ALDH4A1

aldehyde dehydrogenase 4 family, member A1

chr3_-_105588231 0.028 ENST00000545639.1
ENST00000394027.3
ENST00000438603.1
ENST00000447441.1
ENST00000443752.1
 CBLB




Cbl proto-oncogene B, E3 ubiquitin protein ligase




chr20_+_2821340 0.025 ENST00000380445.3
ENST00000380469.3
 VPS16

vacuolar protein sorting 16 homolog (S. cerevisiae)

chr8_+_72587535 0.023 ENST00000519840.1
ENST00000521131.1
 RP11-1144P22.1

RP11-1144P22.1

chr3_-_33138624 0.022 ENST00000445488.2
ENST00000307377.8
ENST00000440656.1
ENST00000436768.1
ENST00000307363.5
 GLB1




galactosidase, beta 1




chr6_-_109703600 0.022 ENST00000512821.1
 CD164
CD164 molecule, sialomucin
chr1_+_87380299 0.021 ENST00000370551.4
ENST00000370550.5
 HS2ST1

heparan sulfate 2-O-sulfotransferase 1

chr19_-_14629224 0.020 ENST00000254322.2
 DNAJB1
DnaJ (Hsp40) homolog, subfamily B, member 1
chr17_+_18218587 0.020 ENST00000406438.3
 SMCR8
Smith-Magenis syndrome chromosome region, candidate 8
chr6_+_30585486 0.020 ENST00000259873.4
ENST00000506373.2
 MRPS18B

mitochondrial ribosomal protein S18B

chr16_+_31539183 0.019 ENST00000302312.4
 AHSP
alpha hemoglobin stabilizing protein
chr19_+_7694623 0.019 ENST00000594797.1
ENST00000456958.3
ENST00000601406.1
 PET100


PET100 homolog (S. cerevisiae)


chr22_-_30987837 0.017 ENST00000335214.6
 PES1
pescadillo ribosomal biogenesis factor 1
chr16_+_20499024 0.016 ENST00000593357.1
 AC137056.1
Uncharacterized protein; cDNA FLJ34659 fis, clone KIDNE2018863
chr20_-_2821271 0.015 ENST00000448755.1
ENST00000360652.2
 PCED1A

PC-esterase domain containing 1A

chr5_+_176560007 0.015 ENST00000510954.1
ENST00000354179.4
 NSD1

nuclear receptor binding SET domain protein 1

chr15_+_92937144 0.014 ENST00000539113.1
ENST00000555434.1
 ST8SIA2

ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2

chr19_-_39390440 0.013 ENST00000249396.7
ENST00000414941.1
ENST00000392081.2
 SIRT2


sirtuin 2


chr7_+_27779714 0.012 ENST00000265393.6
ENST00000409980.1
ENST00000433216.2
ENST00000396319.2
 TAX1BP1



Tax1 (human T-cell leukemia virus type I) binding protein 1



chr17_-_4269768 0.012 ENST00000396981.2
 UBE2G1
ubiquitin-conjugating enzyme E2G 1
chrX_-_92928557 0.012 ENST00000373079.3
ENST00000475430.2
 NAP1L3

nucleosome assembly protein 1-like 3

chr6_+_43603552 0.011 ENST00000372171.4
 MAD2L1BP
MAD2L1 binding protein
chr17_-_46894576 0.011 ENST00000393382.3
 TTLL6
tubulin tyrosine ligase-like family, member 6
chr19_-_39390350 0.011 ENST00000447739.1
ENST00000358931.5
ENST00000407552.1
 SIRT2


sirtuin 2


chr6_-_109703634 0.011 ENST00000324953.5
ENST00000310786.4
ENST00000275080.7
ENST00000413644.2
 CD164



CD164 molecule, sialomucin



chr22_-_30987849 0.010 ENST00000402284.3
ENST00000354694.7
 PES1

pescadillo ribosomal biogenesis factor 1

chr6_-_33239712 0.010 ENST00000436044.2
 VPS52
vacuolar protein sorting 52 homolog (S. cerevisiae)
chr19_-_40931891 0.010 ENST00000357949.4
 SERTAD1
SERTA domain containing 1
chr17_+_38375574 0.009 ENST00000323571.4
ENST00000585043.1
ENST00000394103.3
ENST00000536600.1
 WIPF2



WAS/WASL interacting protein family, member 2



chr15_+_96873921 0.009 ENST00000394166.3
 NR2F2
nuclear receptor subfamily 2, group F, member 2
chr6_-_33239612 0.008 ENST00000482399.1
ENST00000445902.2
 VPS52

vacuolar protein sorting 52 homolog (S. cerevisiae)

chr2_+_97779233 0.008 ENST00000461153.2
ENST00000420699.2
 ANKRD36

ankyrin repeat domain 36

chr17_+_73008755 0.008 ENST00000584208.1
ENST00000301585.5
 ICT1

immature colon carcinoma transcript 1

chr7_+_49813255 0.007 ENST00000340652.4
 VWC2
von Willebrand factor C domain containing 2
chr13_-_108867101 0.006 ENST00000356922.4
 LIG4
ligase IV, DNA, ATP-dependent
chr2_-_188430478 0.005 ENST00000421427.1
 TFPI
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
chr20_-_2821756 0.005 ENST00000356872.3
ENST00000439542.1
 PCED1A

PC-esterase domain containing 1A

chr1_-_161102367 0.003 ENST00000464113.1
 DEDD
death effector domain containing
chr6_-_109703663 0.002 ENST00000368961.5
 CD164
CD164 molecule, sialomucin
chr2_+_113479063 0.002 ENST00000327581.4
 NT5DC4
5'-nucleotidase domain containing 4

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:1903697 negative regulation of microvillus assembly(GO:1903697)
0.0 0.1 GO:0035915 pore formation in membrane of other organism(GO:0035915)
0.0 0.1 GO:0002316 follicular B cell differentiation(GO:0002316)
0.0 0.1 GO:0019470 4-hydroxyproline catabolic process(GO:0019470)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0030492 hemoglobin binding(GO:0030492)
0.0 0.4 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.1 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)