Motif ID: MAF_NRL

Z-value: 0.966

Transcription factors associated with MAF_NRL:

Gene SymbolEntrez IDGene Name
MAF ENSG00000178573.6 MAF
NRL ENSG00000129535.8 NRL

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
MAFhg19_v2_chr16_-_79633799_796338720.501.4e-02Click!
NRLhg19_v2_chr14_-_24551137_24551178,
hg19_v2_chr14_-_24551195_24551214
-0.433.8e-02Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of MAF_NRL

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_-_152386732 3.580 ENST00000271835.3
CRNN
cornulin
chr17_-_38859996 3.280 ENST00000264651.2
KRT24
keratin 24
chr1_+_24645807 2.896 ENST00000361548.4
GRHL3
grainyhead-like 3 (Drosophila)
chr1_+_24645865 2.884 ENST00000342072.4
GRHL3
grainyhead-like 3 (Drosophila)
chr1_+_24646002 2.832 ENST00000356046.2
GRHL3
grainyhead-like 3 (Drosophila)
chr17_-_39769005 2.285 ENST00000301653.4
ENST00000593067.1
KRT16

keratin 16

chr19_-_51471362 1.958 ENST00000376853.4
ENST00000424910.2
KLK6

kallikrein-related peptidase 6

chr4_-_57547454 1.868 ENST00000556376.2
HOPX
HOP homeobox
chr2_+_113885138 1.650 ENST00000409930.3
IL1RN
interleukin 1 receptor antagonist
chr11_-_2924720 1.633 ENST00000455942.2
SLC22A18AS
solute carrier family 22 (organic cation transporter), member 18 antisense
chr2_-_190044480 1.508 ENST00000374866.3
COL5A2
collagen, type V, alpha 2
chr20_+_33759854 1.320 ENST00000216968.4
PROCR
protein C receptor, endothelial
chr11_-_2924970 1.263 ENST00000533594.1
SLC22A18AS
solute carrier family 22 (organic cation transporter), member 18 antisense
chr22_+_31489344 1.254 ENST00000404574.1
SMTN
smoothelin
chr4_-_57547870 1.240 ENST00000381260.3
ENST00000420433.1
ENST00000554144.1
ENST00000557328.1
HOPX



HOP homeobox



chr19_-_51537982 1.194 ENST00000525263.1
KLK12
kallikrein-related peptidase 12
chr1_+_152956549 1.184 ENST00000307122.2
SPRR1A
small proline-rich protein 1A
chr3_+_188664988 1.178 ENST00000433971.1
TPRG1
tumor protein p63 regulated 1
chr12_+_53662073 1.175 ENST00000553219.1
ENST00000257934.4
ESPL1

extra spindle pole bodies homolog 1 (S. cerevisiae)

chr19_-_51456321 1.137 ENST00000391809.2
KLK5
kallikrein-related peptidase 5
chr11_+_118826999 1.134 ENST00000264031.2
UPK2
uroplakin 2
chr19_-_51456344 1.127 ENST00000336334.3
ENST00000593428.1
KLK5

kallikrein-related peptidase 5

chr21_+_30502806 1.104 ENST00000399928.1
ENST00000399926.1
MAP3K7CL

MAP3K7 C-terminal like

chr5_-_156390230 1.046 ENST00000407087.3
ENST00000274532.2
TIMD4

T-cell immunoglobulin and mucin domain containing 4

chr3_-_50340996 1.035 ENST00000266031.4
ENST00000395143.2
ENST00000457214.2
ENST00000447605.2
ENST00000418723.1
ENST00000395144.2
HYAL1





hyaluronoglucosaminidase 1





chr7_+_40174565 1.028 ENST00000309930.5
ENST00000401647.2
ENST00000335693.4
ENST00000413931.1
ENST00000416370.1
ENST00000540834.1
C7orf10





succinylCoA:glutarate-CoA transferase





chr9_+_139839686 1.007 ENST00000371634.2
C8G
complement component 8, gamma polypeptide
chr19_-_51538148 0.975 ENST00000319590.4
ENST00000250351.4
KLK12

kallikrein-related peptidase 12

chr19_-_51538118 0.970 ENST00000529888.1
KLK12
kallikrein-related peptidase 12
chr3_+_42897512 0.966 ENST00000493193.1
ACKR2
atypical chemokine receptor 2
chr20_+_34203794 0.947 ENST00000374273.3
SPAG4
sperm associated antigen 4
chr11_-_2160180 0.904 ENST00000381406.4
IGF2
insulin-like growth factor 2 (somatomedin A)
chr18_+_61554932 0.891 ENST00000299502.4
ENST00000457692.1
ENST00000413956.1
SERPINB2


serpin peptidase inhibitor, clade B (ovalbumin), member 2


chr2_+_210444748 0.859 ENST00000392194.1
MAP2
microtubule-associated protein 2
chr2_+_90458201 0.856 ENST00000603238.1
CH17-132F21.1
Uncharacterized protein
chr16_-_46655538 0.853 ENST00000303383.3
SHCBP1
SHC SH2-domain binding protein 1
chrX_-_54824673 0.839 ENST00000218436.6
ITIH6
inter-alpha-trypsin inhibitor heavy chain family, member 6
chr1_+_17575584 0.837 ENST00000375460.3
PADI3
peptidyl arginine deiminase, type III
chr19_+_15052301 0.816 ENST00000248072.3
OR7C2
olfactory receptor, family 7, subfamily C, member 2
chr11_-_12030905 0.811 ENST00000326932.4
DKK3
dickkopf WNT signaling pathway inhibitor 3
chr7_-_41742697 0.805 ENST00000242208.4
INHBA
inhibin, beta A
chr1_-_197115818 0.805 ENST00000367409.4
ENST00000294732.7
ASPM

asp (abnormal spindle) homolog, microcephaly associated (Drosophila)

chr2_+_210444142 0.790 ENST00000360351.4
ENST00000361559.4
MAP2

microtubule-associated protein 2

chr15_-_70994612 0.761 ENST00000558758.1
ENST00000379983.2
ENST00000560441.1
UACA


uveal autoantigen with coiled-coil domains and ankyrin repeats


chrX_-_153775426 0.761 ENST00000393562.2
G6PD
glucose-6-phosphate dehydrogenase
chr19_+_16187085 0.758 ENST00000300933.4
TPM4
tropomyosin 4
chr11_-_119599794 0.751 ENST00000264025.3
PVRL1
poliovirus receptor-related 1 (herpesvirus entry mediator C)
chr1_+_22333943 0.750 ENST00000400271.2
CELA3A
chymotrypsin-like elastase family, member 3A
chr12_+_53662110 0.739 ENST00000552462.1
ESPL1
extra spindle pole bodies homolog 1 (S. cerevisiae)
chr2_+_113735575 0.737 ENST00000376489.2
ENST00000259205.4
IL36G

interleukin 36, gamma

chrX_+_41306575 0.733 ENST00000342595.2
ENST00000378220.1
NYX

nyctalopin

chr2_-_211168332 0.728 ENST00000341685.4
MYL1
myosin, light chain 1, alkali; skeletal, fast
chr10_+_120967072 0.709 ENST00000392870.2
GRK5
G protein-coupled receptor kinase 5
chr16_+_46918235 0.693 ENST00000340124.4
GPT2
glutamic pyruvate transaminase (alanine aminotransferase) 2
chr14_+_23654525 0.691 ENST00000399910.1
ENST00000492621.1
C14orf164

chromosome 14 open reading frame 164

chr1_-_201368653 0.686 ENST00000367313.3
LAD1
ladinin 1
chr12_+_53491220 0.673 ENST00000548547.1
ENST00000301464.3
IGFBP6

insulin-like growth factor binding protein 6

chr20_-_17511962 0.648 ENST00000377873.3
BFSP1
beaded filament structural protein 1, filensin
chr1_+_10057274 0.645 ENST00000294435.7
RBP7
retinol binding protein 7, cellular
chr1_-_201368707 0.644 ENST00000391967.2
LAD1
ladinin 1
chr16_-_10868853 0.644 ENST00000572428.1
TVP23A
trans-golgi network vesicle protein 23 homolog A (S. cerevisiae)
chr12_-_52779433 0.633 ENST00000257951.3
KRT84
keratin 84
chr16_+_57279248 0.623 ENST00000562023.1
ENST00000563234.1
ARL2BP

ADP-ribosylation factor-like 2 binding protein

chr1_+_163291680 0.609 ENST00000450453.2
ENST00000524800.1
ENST00000442820.1
ENST00000367900.3
NUF2



NUF2, NDC80 kinetochore complex component



chr12_+_15699286 0.592 ENST00000442921.2
ENST00000542557.1
ENST00000445537.2
ENST00000544244.1
PTPRO



protein tyrosine phosphatase, receptor type, O



chr14_+_96343100 0.592 ENST00000503525.2
LINC00617
long intergenic non-protein coding RNA 617
chr5_+_149877334 0.590 ENST00000523767.1
NDST1
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
chr16_-_84538218 0.585 ENST00000562447.1
ENST00000565765.1
ENST00000535580.1
ENST00000343629.6
TLDC1



TBC/LysM-associated domain containing 1



chr11_+_62186498 0.577 ENST00000278282.2
SCGB1A1
secretoglobin, family 1A, member 1 (uteroglobin)
chr1_-_50489547 0.576 ENST00000371836.1
ENST00000371839.1
ENST00000371838.1
AGBL4


ATP/GTP binding protein-like 4


chr19_+_16186903 0.572 ENST00000588507.1
TPM4
tropomyosin 4
chr6_+_121756809 0.571 ENST00000282561.3
GJA1
gap junction protein, alpha 1, 43kDa
chr11_-_2160611 0.571 ENST00000416167.2
IGF2
insulin-like growth factor 2 (somatomedin A)
chr14_-_23834411 0.567 ENST00000429593.2
EFS
embryonal Fyn-associated substrate
chr1_-_109935819 0.566 ENST00000538502.1
SORT1
sortilin 1
chrX_-_15683147 0.565 ENST00000380342.3
TMEM27
transmembrane protein 27
chr4_+_8201091 0.559 ENST00000382521.3
ENST00000245105.3
ENST00000457650.2
ENST00000539824.1
SH3TC1



SH3 domain and tetratricopeptide repeats 1



chr9_+_4985016 0.553 ENST00000539801.1
JAK2
Janus kinase 2
chr17_-_39526052 0.550 ENST00000251646.3
KRT33B
keratin 33B
chr1_+_206138884 0.548 ENST00000341209.5
ENST00000607379.1
FAM72A

family with sequence similarity 72, member A

chr7_-_113559104 0.537 ENST00000284601.3
PPP1R3A
protein phosphatase 1, regulatory subunit 3A
chrX_+_64887512 0.537 ENST00000360270.5
MSN
moesin
chr19_-_55660561 0.532 ENST00000587758.1
ENST00000356783.5
ENST00000291901.8
ENST00000588426.1
ENST00000588147.1
ENST00000536926.1
ENST00000588981.1
TNNT1






troponin T type 1 (skeletal, slow)






chr16_-_28518153 0.531 ENST00000356897.1
IL27
interleukin 27
chr15_+_41851211 0.523 ENST00000263798.3
TYRO3
TYRO3 protein tyrosine kinase
chr17_+_27573875 0.519 ENST00000225387.3
CRYBA1
crystallin, beta A1
chr3_+_6902794 0.511 ENST00000357716.4
ENST00000486284.1
ENST00000389336.4
ENST00000403881.1
ENST00000402647.2
GRM7




glutamate receptor, metabotropic 7




chr7_-_14028488 0.489 ENST00000405358.4
ETV1
ets variant 1
chr2_-_234763147 0.485 ENST00000411486.2
ENST00000432087.1
ENST00000441687.1
ENST00000414924.1
HJURP



Holliday junction recognition protein



chr7_+_26331541 0.485 ENST00000416246.1
ENST00000338523.4
ENST00000412416.1
SNX10


sorting nexin 10


chr11_+_116700614 0.485 ENST00000375345.1
APOC3
apolipoprotein C-III
chr14_+_93118813 0.483 ENST00000556418.1
RIN3
Ras and Rab interactor 3
chr17_-_10325261 0.483 ENST00000403437.2
MYH8
myosin, heavy chain 8, skeletal muscle, perinatal
chr8_-_145018905 0.477 ENST00000398774.2
PLEC
plectin
chr11_+_116700600 0.475 ENST00000227667.3
APOC3
apolipoprotein C-III
chr2_+_242811874 0.473 ENST00000343216.3
CXXC11
CXXC finger protein 11
chrX_+_12924732 0.471 ENST00000218032.6
ENST00000311912.5
TLR8

toll-like receptor 8

chrX_+_51075658 0.466 ENST00000356450.2
NUDT10
nudix (nucleoside diphosphate linked moiety X)-type motif 10
chr14_-_77787198 0.466 ENST00000261534.4
POMT2
protein-O-mannosyltransferase 2
chr17_+_6544356 0.465 ENST00000574838.1
TXNDC17
thioredoxin domain containing 17
chr11_-_66103932 0.459 ENST00000311320.4
RIN1
Ras and Rab interactor 1
chr14_-_23058063 0.451 ENST00000538631.1
ENST00000543337.1
ENST00000250498.4
DAD1


defender against cell death 1


chr16_+_71392616 0.449 ENST00000349553.5
ENST00000302628.4
ENST00000562305.1
CALB2


calbindin 2


chr5_+_68485433 0.444 ENST00000502689.1
CENPH
centromere protein H
chr9_+_4985228 0.441 ENST00000381652.3
JAK2
Janus kinase 2
chr1_-_173020056 0.440 ENST00000239468.2
ENST00000404377.3
TNFSF18

tumor necrosis factor (ligand) superfamily, member 18

chr10_+_5566916 0.440 ENST00000315238.1
CALML3
calmodulin-like 3
chrX_-_51239425 0.439 ENST00000375992.3
NUDT11
nudix (nucleoside diphosphate linked moiety X)-type motif 11
chr19_-_7058651 0.434 ENST00000333843.4
MBD3L3
methyl-CpG binding domain protein 3-like 3
chr17_+_7341586 0.428 ENST00000575235.1
FGF11
fibroblast growth factor 11
chr12_-_11184006 0.427 ENST00000390675.2
TAS2R31
taste receptor, type 2, member 31
chr19_-_49015050 0.425 ENST00000600059.1
LMTK3
lemur tyrosine kinase 3
chr19_+_45418067 0.424 ENST00000589078.1
ENST00000586638.1
APOC1

apolipoprotein C-I

chr1_+_200842083 0.423 ENST00000304244.2
GPR25
G protein-coupled receptor 25
chr1_-_40237020 0.422 ENST00000327582.5
OXCT2
3-oxoacid CoA transferase 2
chr7_+_76139925 0.420 ENST00000394849.1
UPK3B
uroplakin 3B
chr3_+_130569592 0.417 ENST00000533801.2
ATP2C1
ATPase, Ca++ transporting, type 2C, member 1
chr3_-_42743006 0.414 ENST00000310417.5
HHATL
hedgehog acyltransferase-like
chr1_-_150979333 0.414 ENST00000312210.5
FAM63A
family with sequence similarity 63, member A
chr7_-_107443652 0.413 ENST00000340010.5
ENST00000422236.2
ENST00000453332.1
SLC26A3


solute carrier family 26 (anion exchanger), member 3


chr15_-_40212363 0.410 ENST00000299092.3
GPR176
G protein-coupled receptor 176
chr10_+_102505468 0.408 ENST00000361791.3
ENST00000355243.3
ENST00000428433.1
ENST00000370296.2
PAX2



paired box 2



chr6_-_131321863 0.406 ENST00000528282.1
EPB41L2
erythrocyte membrane protein band 4.1-like 2
chr15_-_59665062 0.406 ENST00000288235.4
MYO1E
myosin IE
chr14_+_77787227 0.404 ENST00000216465.5
ENST00000361389.4
ENST00000554279.1
ENST00000557639.1
ENST00000349555.3
ENST00000556627.1
ENST00000557053.1
GSTZ1






glutathione S-transferase zeta 1






chr1_-_150780757 0.402 ENST00000271651.3
CTSK
cathepsin K
chrX_+_123480375 0.401 ENST00000360027.4
SH2D1A
SH2 domain containing 1A
chr10_-_98031265 0.398 ENST00000224337.5
ENST00000371176.2
BLNK

B-cell linker

chr13_-_24007815 0.396 ENST00000382298.3
SACS
spastic ataxia of Charlevoix-Saguenay (sacsin)
chr1_+_12834984 0.387 ENST00000357726.4
PRAMEF12
PRAME family member 12
chr20_+_30555805 0.386 ENST00000562532.2
XKR7
XK, Kell blood group complex subunit-related family, member 7
chr11_-_64646086 0.382 ENST00000320631.3
EHD1
EH-domain containing 1
chr11_-_124311054 0.381 ENST00000328064.2
OR8B8
olfactory receptor, family 8, subfamily B, member 8
chrX_+_17755563 0.379 ENST00000380045.3
ENST00000380041.3
ENST00000380043.3
ENST00000398080.1
SCML1



sex comb on midleg-like 1 (Drosophila)



chr3_+_12392971 0.376 ENST00000287820.6
PPARG
peroxisome proliferator-activated receptor gamma
chr3_-_59035673 0.376 ENST00000491845.1
ENST00000472469.1
ENST00000471288.1
ENST00000295966.7
C3orf67



chromosome 3 open reading frame 67



chr3_+_50192499 0.374 ENST00000413852.1
SEMA3F
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr8_+_32579341 0.369 ENST00000519240.1
ENST00000539990.1
NRG1

neuregulin 1

chr20_+_2276639 0.368 ENST00000381458.5
TGM3
transglutaminase 3
chr6_-_42419649 0.368 ENST00000372922.4
ENST00000541110.1
ENST00000372917.4
TRERF1


transcriptional regulating factor 1


chr19_+_45417504 0.365 ENST00000588750.1
ENST00000588802.1
APOC1

apolipoprotein C-I

chr10_-_99052382 0.365 ENST00000466484.1
ENST00000358531.4
ENST00000453547.2
ENST00000316676.8
ENST00000358308.3
ARHGAP19

ARHGAP19-SLIT1


Rho GTPase activating protein 19

ARHGAP19-SLIT1 readthrough (NMD candidate)


chr5_-_16742330 0.364 ENST00000505695.1
ENST00000427430.2
MYO10

myosin X

chr17_-_10276319 0.364 ENST00000252172.4
ENST00000418404.3
MYH13

myosin, heavy chain 13, skeletal muscle

chr10_-_11653753 0.361 ENST00000609104.1
USP6NL
USP6 N-terminal like
chr2_-_37193606 0.361 ENST00000379213.2
ENST00000263918.4
STRN

striatin, calmodulin binding protein

chr2_-_85636928 0.360 ENST00000449030.1
CAPG
capping protein (actin filament), gelsolin-like
chr11_-_113577014 0.353 ENST00000544634.1
ENST00000539732.1
ENST00000538770.1
ENST00000536856.1
ENST00000544476.1
TMPRSS5




transmembrane protease, serine 5




chr1_+_163291732 0.353 ENST00000271452.3
NUF2
NUF2, NDC80 kinetochore complex component
chr1_-_150978953 0.347 ENST00000493834.2
FAM63A
family with sequence similarity 63, member A
chr15_-_89764929 0.346 ENST00000268125.5
RLBP1
retinaldehyde binding protein 1
chr12_+_50366620 0.345 ENST00000315520.5
AQP6
aquaporin 6, kidney specific
chr12_-_102874330 0.343 ENST00000307046.8
IGF1
insulin-like growth factor 1 (somatomedin C)
chr22_+_45148432 0.337 ENST00000389774.2
ENST00000396119.2
ENST00000336963.4
ENST00000356099.6
ENST00000412433.1
ARHGAP8




Rho GTPase activating protein 8




chr11_-_10829851 0.336 ENST00000532082.1
EIF4G2
eukaryotic translation initiation factor 4 gamma, 2
chr11_-_3862206 0.336 ENST00000351018.4
RHOG
ras homolog family member G
chr2_+_27719697 0.335 ENST00000264717.2
ENST00000424318.2
GCKR

glucokinase (hexokinase 4) regulator

chr6_+_31582961 0.335 ENST00000376059.3
ENST00000337917.7
AIF1

allograft inflammatory factor 1

chr16_+_3405889 0.333 ENST00000304936.2
OR2C1
olfactory receptor, family 2, subfamily C, member 1
chr1_+_161691353 0.333 ENST00000367948.2
FCRLB
Fc receptor-like B
chr15_-_90294523 0.331 ENST00000300057.4
MESP1
mesoderm posterior 1 homolog (mouse)
chr2_+_173940163 0.330 ENST00000539448.1
MLTK
Mitogen-activated protein kinase kinase kinase MLT
chr12_-_102874102 0.330 ENST00000392905.2
IGF1
insulin-like growth factor 1 (somatomedin C)
chr14_-_102829051 0.329 ENST00000536961.2
ENST00000541568.2
ENST00000216756.6
CINP


cyclin-dependent kinase 2 interacting protein


chr3_+_150264555 0.329 ENST00000406576.3
ENST00000482093.1
ENST00000273435.5
EIF2A


eukaryotic translation initiation factor 2A, 65kDa


chr17_+_18625336 0.328 ENST00000395671.4
ENST00000571542.1
ENST00000395672.2
ENST00000414850.2
ENST00000424146.2
TRIM16L




tripartite motif containing 16-like




chr11_-_113577052 0.328 ENST00000540540.1
ENST00000545579.1
ENST00000538955.1
ENST00000299882.5
TMPRSS5



transmembrane protease, serine 5



chr10_-_98031310 0.326 ENST00000427367.2
ENST00000413476.2
BLNK

B-cell linker

chr12_+_70219052 0.325 ENST00000552032.2
ENST00000547771.2
MYRFL

myelin regulatory factor-like

chr11_+_6226782 0.325 ENST00000316375.2
C11orf42
chromosome 11 open reading frame 42
chr9_+_139557360 0.323 ENST00000308874.7
ENST00000406555.3
ENST00000492862.2
EGFL7


EGF-like-domain, multiple 7


chr3_+_158991025 0.322 ENST00000337808.6
IQCJ-SCHIP1
IQCJ-SCHIP1 readthrough
chr16_+_28889801 0.321 ENST00000395503.4
ATP2A1
ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
chr19_+_45417921 0.320 ENST00000252491.4
ENST00000592885.1
ENST00000589781.1
APOC1


apolipoprotein C-I


chr16_+_27078219 0.317 ENST00000418886.1
C16orf82
chromosome 16 open reading frame 82
chr7_+_114562909 0.317 ENST00000423503.1
ENST00000427207.1
MDFIC

MyoD family inhibitor domain containing

chr8_+_80523321 0.316 ENST00000518111.1
STMN2
stathmin-like 2
chr11_+_28129795 0.315 ENST00000406787.3
ENST00000342303.5
ENST00000403099.1
ENST00000407364.3
METTL15



methyltransferase like 15



chr1_+_32687971 0.315 ENST00000373586.1
EIF3I
eukaryotic translation initiation factor 3, subunit I
chr7_+_65540853 0.313 ENST00000380839.4
ENST00000395332.3
ENST00000362000.5
ENST00000395331.3
ASL



argininosuccinate lyase



chr3_+_150264458 0.310 ENST00000487799.1
ENST00000460851.1
EIF2A

eukaryotic translation initiation factor 2A, 65kDa

chr19_-_43422019 0.306 ENST00000402603.4
ENST00000594375.1
PSG6

pregnancy specific beta-1-glycoprotein 6

chr6_+_80129989 0.305 ENST00000429444.1
RP1-232L24.3
RP1-232L24.3
chrX_+_123480194 0.305 ENST00000371139.4
SH2D1A
SH2 domain containing 1A
chr6_+_132455118 0.302 ENST00000458028.1
LINC01013
long intergenic non-protein coding RNA 1013
chr14_+_22508822 0.301 ENST00000390448.3
TRAV20
T cell receptor alpha variable 20
chr1_-_161279749 0.301 ENST00000533357.1
ENST00000360451.6
ENST00000336559.4
MPZ


myelin protein zero


chr20_-_13971255 0.301 ENST00000284951.5
ENST00000378072.5
SEL1L2

sel-1 suppressor of lin-12-like 2 (C. elegans)

chr17_-_3301704 0.300 ENST00000322608.2
OR1E1
olfactory receptor, family 1, subfamily E, member 1
chrX_+_78426469 0.300 ENST00000276077.1
GPR174
G protein-coupled receptor 174
chr11_+_31391381 0.299 ENST00000465995.1
ENST00000536040.1
DNAJC24

DnaJ (Hsp40) homolog, subfamily C, member 24

chr1_+_53098862 0.298 ENST00000517870.1
FAM159A
family with sequence similarity 159, member A
chr17_-_27503770 0.296 ENST00000533112.1
MYO18A
myosin XVIIIA
chr3_+_94657086 0.296 ENST00000463200.1
LINC00879
long intergenic non-protein coding RNA 879
chrX_-_153637612 0.294 ENST00000369807.1
ENST00000369808.3
DNASE1L1

deoxyribonuclease I-like 1

chr17_+_18218587 0.294 ENST00000406438.3
SMCR8
Smith-Magenis syndrome chromosome region, candidate 8
chr11_-_123756334 0.292 ENST00000528595.1
ENST00000375026.2
TMEM225

transmembrane protein 225

chr11_-_66104237 0.291 ENST00000530056.1
RIN1
Ras and Rab interactor 1
chr16_-_46865286 0.291 ENST00000285697.4
C16orf87
chromosome 16 open reading frame 87
chr11_-_62783303 0.289 ENST00000336232.2
ENST00000430500.2
SLC22A8

solute carrier family 22 (organic anion transporter), member 8


Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.8 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.5 1.9 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.5 8.6 GO:0090179 planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.4 2.3 GO:0002803 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803)
0.3 1.4 GO:0010900 negative regulation of phosphatidylcholine catabolic process(GO:0010900)
0.3 1.0 GO:2000910 negative regulation of cholesterol import(GO:0060621) negative regulation of sterol import(GO:2000910)
0.3 0.8 GO:0045578 negative regulation of B cell differentiation(GO:0045578) regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.3 0.8 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.3 1.0 GO:1900106 hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.3 0.8 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
0.2 1.1 GO:1904075 trophectodermal cell proliferation(GO:0001834) regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075)
0.2 0.8 GO:1902613 regulation of anti-Mullerian hormone signaling pathway(GO:1902612) negative regulation of anti-Mullerian hormone signaling pathway(GO:1902613) anti-Mullerian hormone signaling pathway(GO:1990262)
0.2 1.0 GO:1902728 mineralocorticoid receptor signaling pathway(GO:0031959) positive regulation of skeletal muscle satellite cell proliferation(GO:1902724) positive regulation of growth factor dependent skeletal muscle satellite cell proliferation(GO:1902728)
0.2 0.6 GO:0036058 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.2 0.6 GO:0010652 regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652)
0.2 0.6 GO:0014724 regulation of twitch skeletal muscle contraction(GO:0014724) fast-twitch skeletal muscle fiber contraction(GO:0031443) relaxation of skeletal muscle(GO:0090076)
0.2 1.7 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.2 0.7 GO:0042853 L-alanine metabolic process(GO:0042851) L-alanine catabolic process(GO:0042853)
0.2 0.8 GO:0018101 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.2 1.5 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.2 0.9 GO:1901908 diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.1 0.6 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.1 0.4 GO:0006500 N-terminal protein palmitoylation(GO:0006500)
0.1 0.6 GO:1990928 response to amino acid starvation(GO:1990928)
0.1 0.4 GO:0043163 cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229)
0.1 2.3 GO:0051546 keratinocyte migration(GO:0051546)
0.1 0.4 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.1 0.5 GO:0045356 positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.1 0.6 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.1 0.5 GO:0045065 cytotoxic T cell differentiation(GO:0045065)
0.1 3.1 GO:0001829 trophectodermal cell differentiation(GO:0001829)
0.1 0.4 GO:2000329 negative regulation of T-helper 17 cell lineage commitment(GO:2000329)
0.1 0.3 GO:0019285 glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456)
0.1 0.2 GO:0044028 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.1 0.3 GO:0042450 arginine biosynthetic process via ornithine(GO:0042450)
0.1 0.8 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.1 0.5 GO:0014738 regulation of muscle hyperplasia(GO:0014738)
0.1 0.4 GO:0039017 vestibulocochlear nerve formation(GO:0021650) pronephric field specification(GO:0039003) pattern specification involved in pronephros development(GO:0039017) kidney rudiment formation(GO:0072003) kidney field specification(GO:0072004) regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis(GO:0072039) negative regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis(GO:0072040) regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis(GO:0072304) negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis(GO:0072305) mesenchymal stem cell maintenance involved in metanephric nephron morphogenesis(GO:0072309) mesenchymal cell apoptotic process involved in metanephros development(GO:1900200) apoptotic process involved in metanephric collecting duct development(GO:1900204) apoptotic process involved in metanephric nephron tubule development(GO:1900205) regulation of mesenchymal cell apoptotic process involved in metanephros development(GO:1900211) negative regulation of mesenchymal cell apoptotic process involved in metanephros development(GO:1900212) regulation of apoptotic process involved in metanephric collecting duct development(GO:1900214) negative regulation of apoptotic process involved in metanephric collecting duct development(GO:1900215) regulation of apoptotic process involved in metanephric nephron tubule development(GO:1900217) negative regulation of apoptotic process involved in metanephric nephron tubule development(GO:1900218) mesenchymal cell apoptotic process involved in nephron morphogenesis(GO:1901145) mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis(GO:1901147) negative regulation of somatic stem cell population maintenance(GO:1904673) regulation of metanephric DCT cell differentiation(GO:2000592) positive regulation of metanephric DCT cell differentiation(GO:2000594)
0.1 0.4 GO:0010897 negative regulation of triglyceride catabolic process(GO:0010897)
0.1 0.8 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.1 0.3 GO:1903028 positive regulation of opsonization(GO:1903028)
0.1 0.6 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.1 0.2 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.1 0.4 GO:2000230 regulation of cholesterol transporter activity(GO:0060694) negative regulation of pancreatic stellate cell proliferation(GO:2000230)
0.1 0.4 GO:1990502 dense core granule maturation(GO:1990502)
0.1 0.5 GO:1904098 regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
0.1 0.3 GO:0043311 positive regulation of eosinophil degranulation(GO:0043311) positive regulation of eosinophil activation(GO:1902568)
0.1 0.3 GO:1902869 commitment of multipotent stem cells to neuronal lineage in forebrain(GO:0021898) regulation of amacrine cell differentiation(GO:1902869)
0.1 0.3 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.1 0.3 GO:0003335 corneocyte development(GO:0003335)
0.1 1.9 GO:0016540 protein autoprocessing(GO:0016540)
0.1 0.2 GO:0051088 PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.1 0.4 GO:0046952 ketone body catabolic process(GO:0046952)
0.1 0.2 GO:0006597 spermine biosynthetic process(GO:0006597)
0.1 0.5 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.1 0.2 GO:0070173 regulation of enamel mineralization(GO:0070173)
0.1 0.3 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
0.1 0.2 GO:0021558 trochlear nerve development(GO:0021558)
0.1 0.6 GO:0036486 trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486)
0.1 0.2 GO:0050720 interleukin-1 beta biosynthetic process(GO:0050720)
0.1 0.3 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.1 0.5 GO:0014050 negative regulation of glutamate secretion(GO:0014050)
0.1 0.6 GO:0032696 negative regulation of interleukin-13 production(GO:0032696)
0.1 0.7 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.1 0.3 GO:0045359 positive regulation of interferon-beta biosynthetic process(GO:0045359)
0.1 0.5 GO:2001137 positive regulation of endocytic recycling(GO:2001137)
0.1 0.4 GO:0035166 post-embryonic hemopoiesis(GO:0035166)
0.1 8.9 GO:0070268 cornification(GO:0070268)
0.1 0.2 GO:1902396 protein localization to bicellular tight junction(GO:1902396)
0.1 0.2 GO:0002585 myeloid dendritic cell activation involved in immune response(GO:0002277) positive regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002582) positive regulation of antigen processing and presentation of peptide antigen(GO:0002585) positive regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002588)
0.1 1.3 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.1 0.5 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.1 0.2 GO:1990258 box C/D snoRNA 3'-end processing(GO:0000494) box C/D snoRNA metabolic process(GO:0033967) box C/D snoRNA processing(GO:0034963) histone glutamine methylation(GO:1990258)
0.1 0.5 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.1 0.6 GO:0015014 protein sulfation(GO:0006477) heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.1 0.2 GO:0006788 heme oxidation(GO:0006788)
0.1 0.2 GO:2001045 closure of optic fissure(GO:0061386) negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.1 0.5 GO:0006572 tyrosine catabolic process(GO:0006572)
0.1 0.2 GO:1905167 positive regulation of lysosomal protein catabolic process(GO:1905167)
0.1 0.2 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.1 0.3 GO:0051835 positive regulation of synapse structural plasticity(GO:0051835)
0.1 0.2 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.1 0.1 GO:0097325 melanocyte proliferation(GO:0097325)
0.1 0.3 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
0.1 0.4 GO:0021842 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.1 0.6 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.1 0.1 GO:0035587 purinergic receptor signaling pathway(GO:0035587)
0.1 0.2 GO:0032641 lymphotoxin A production(GO:0032641) lymphotoxin A biosynthetic process(GO:0042109)
0.1 0.4 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0 0.2 GO:0071226 response to molecule of fungal origin(GO:0002238) cellular response to molecule of fungal origin(GO:0071226)
0.0 0.3 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 0.3 GO:0006177 GMP biosynthetic process(GO:0006177)
0.0 0.1 GO:0032304 negative regulation of icosanoid secretion(GO:0032304)
0.0 0.4 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.0 0.2 GO:0044778 meiotic DNA integrity checkpoint(GO:0044778)
0.0 1.0 GO:0045954 positive regulation of natural killer cell mediated cytotoxicity(GO:0045954)
0.0 0.3 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 0.2 GO:0046968 peptide antigen transport(GO:0046968)
0.0 0.2 GO:0071504 cellular response to heparin(GO:0071504)
0.0 0.6 GO:0070307 lens fiber cell development(GO:0070307)
0.0 0.3 GO:0051012 microtubule sliding(GO:0051012)
0.0 3.3 GO:0030049 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.0 0.2 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.0 0.2 GO:0002215 defense response to nematode(GO:0002215)
0.0 0.6 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 0.3 GO:0070475 rRNA base methylation(GO:0070475)
0.0 0.2 GO:2000504 positive regulation of blood vessel remodeling(GO:2000504)
0.0 0.3 GO:0038060 nitric oxide-cGMP-mediated signaling pathway(GO:0038060)
0.0 0.5 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.1 GO:0060380 regulation of single-stranded telomeric DNA binding(GO:0060380) positive regulation of single-stranded telomeric DNA binding(GO:0060381)
0.0 0.3 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.0 0.1 GO:1904717 excitatory chemical synaptic transmission(GO:0098976) regulation of AMPA glutamate receptor clustering(GO:1904717) positive regulation of AMPA glutamate receptor clustering(GO:1904719)
0.0 0.1 GO:0009107 lipoate biosynthetic process(GO:0009107)
0.0 0.2 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.0 0.1 GO:0048627 myoblast development(GO:0048627)
0.0 0.6 GO:0060068 vagina development(GO:0060068)
0.0 0.2 GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0 0.5 GO:0008212 mineralocorticoid biosynthetic process(GO:0006705) mineralocorticoid metabolic process(GO:0008212)
0.0 0.6 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.0 0.1 GO:0042369 vitamin D catabolic process(GO:0042369)
0.0 0.3 GO:0042760 very long-chain fatty acid catabolic process(GO:0042760)
0.0 0.7 GO:0060081 membrane hyperpolarization(GO:0060081)
0.0 0.2 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.0 0.2 GO:0008204 ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
0.0 0.1 GO:0021966 corticospinal neuron axon guidance(GO:0021966)
0.0 0.4 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.2 GO:1903301 fructose 2,6-bisphosphate metabolic process(GO:0006003) positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.0 0.1 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.0 0.3 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 0.2 GO:0019236 response to pheromone(GO:0019236)
0.0 0.3 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.0 0.4 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 0.3 GO:0031639 plasminogen activation(GO:0031639)
0.0 0.1 GO:0071934 thiamine transmembrane transport(GO:0071934)
0.0 0.2 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.0 0.1 GO:0021816 lamellipodium assembly involved in ameboidal cell migration(GO:0003363) extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration(GO:0021816)
0.0 0.1 GO:0007499 ectoderm and mesoderm interaction(GO:0007499) female genitalia morphogenesis(GO:0048807)
0.0 0.9 GO:0042730 fibrinolysis(GO:0042730)
0.0 1.3 GO:0050819 negative regulation of coagulation(GO:0050819)
0.0 0.1 GO:0061056 sclerotome development(GO:0061056)
0.0 0.4 GO:0051382 kinetochore assembly(GO:0051382)
0.0 0.3 GO:0097396 response to interleukin-17(GO:0097396) cellular response to interleukin-17(GO:0097398)
0.0 0.3 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 0.4 GO:1904778 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.0 0.3 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.0 0.3 GO:0006776 vitamin A metabolic process(GO:0006776)
0.0 0.6 GO:1903204 negative regulation of oxidative stress-induced neuron death(GO:1903204)
0.0 0.6 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.0 0.1 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0 0.1 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.0 0.1 GO:0007406 negative regulation of neuroblast proliferation(GO:0007406)
0.0 0.1 GO:0010728 regulation of hydrogen peroxide biosynthetic process(GO:0010728)
0.0 0.2 GO:0021564 vagus nerve development(GO:0021564)
0.0 0.0 GO:0035995 detection of muscle stretch(GO:0035995)
0.0 0.2 GO:0002774 Fc receptor mediated inhibitory signaling pathway(GO:0002774)
0.0 0.2 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.0 2.3 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.1 GO:0002370 natural killer cell cytokine production(GO:0002370) regulation of natural killer cell cytokine production(GO:0002727) negative regulation of natural killer cell cytokine production(GO:0002728)
0.0 0.6 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.1 GO:0021526 medial motor column neuron differentiation(GO:0021526)
0.0 0.1 GO:0050902 leukocyte adhesive activation(GO:0050902)
0.0 0.2 GO:0002005 angiotensin catabolic process in blood(GO:0002005)
0.0 0.3 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 0.2 GO:0090646 mitochondrial tRNA processing(GO:0090646)
0.0 0.1 GO:1900248 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
0.0 0.1 GO:1904580 negative regulation of interleukin-2 biosynthetic process(GO:0045085) regulation of intracellular mRNA localization(GO:1904580) positive regulation of intracellular mRNA localization(GO:1904582)
0.0 0.1 GO:0019249 lactate biosynthetic process(GO:0019249)
0.0 0.3 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.0 0.1 GO:0039663 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.0 0.3 GO:0033227 dsRNA transport(GO:0033227)
0.0 0.4 GO:0060347 heart trabecula formation(GO:0060347)
0.0 0.1 GO:0010265 SCF complex assembly(GO:0010265)
0.0 0.1 GO:0048341 paraxial mesoderm formation(GO:0048341)
0.0 0.1 GO:0051414 response to cortisol(GO:0051414)
0.0 0.2 GO:0090481 pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.0 0.1 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.0 0.6 GO:0007638 mechanosensory behavior(GO:0007638)
0.0 0.3 GO:0021894 cerebral cortex GABAergic interneuron differentiation(GO:0021892) cerebral cortex GABAergic interneuron development(GO:0021894)
0.0 0.1 GO:0015842 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842)
0.0 0.7 GO:0097503 sialylation(GO:0097503)
0.0 1.1 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.0 0.1 GO:2000110 negative regulation of macrophage apoptotic process(GO:2000110)
0.0 0.1 GO:0043449 olfactory learning(GO:0008355) cellular alkene metabolic process(GO:0043449)
0.0 0.9 GO:0019835 cytolysis(GO:0019835)
0.0 0.1 GO:0038188 cholecystokinin signaling pathway(GO:0038188)
0.0 0.1 GO:0010701 positive regulation of norepinephrine secretion(GO:0010701)
0.0 0.5 GO:0071539 protein localization to centrosome(GO:0071539)
0.0 0.1 GO:0060017 parathyroid gland development(GO:0060017)
0.0 0.1 GO:2001268 negative regulation of histone H3-K9 dimethylation(GO:1900110) regulation of TORC2 signaling(GO:1903939) negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001268)
0.0 0.5 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.0 0.1 GO:0000066 mitochondrial ornithine transport(GO:0000066)
0.0 0.5 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.0 0.4 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.0 0.1 GO:0002881 microglial cell activation involved in immune response(GO:0002282) negative regulation of chronic inflammatory response to non-antigenic stimulus(GO:0002881)
0.0 0.2 GO:0097091 synaptic vesicle clustering(GO:0097091)
0.0 0.8 GO:0050913 sensory perception of bitter taste(GO:0050913)
0.0 0.1 GO:0032776 DNA methylation on cytosine(GO:0032776)
0.0 0.5 GO:0034080 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0 4.0 GO:0009408 response to heat(GO:0009408)
0.0 0.3 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.0 0.1 GO:1904627 response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.0 0.1 GO:0061146 Peyer's patch morphogenesis(GO:0061146)
0.0 0.1 GO:0060363 cranial suture morphogenesis(GO:0060363)
0.0 0.2 GO:0010666 positive regulation of striated muscle cell apoptotic process(GO:0010663) positive regulation of cardiac muscle cell apoptotic process(GO:0010666)
0.0 0.2 GO:0050910 detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.0 1.6 GO:0001578 microtubule bundle formation(GO:0001578)
0.0 0.1 GO:0043418 homocysteine catabolic process(GO:0043418)
0.0 0.1 GO:0033484 nitric oxide homeostasis(GO:0033484)
0.0 0.0 GO:0071288 cellular response to mercury ion(GO:0071288)
0.0 0.2 GO:0010968 regulation of microtubule nucleation(GO:0010968)
0.0 0.0 GO:1900276 regulation of proteinase activated receptor activity(GO:1900276) negative regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900737)
0.0 0.2 GO:0006228 UTP biosynthetic process(GO:0006228)
0.0 0.1 GO:0097211 response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.0 0.2 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.0 0.1 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.0 0.1 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.0 0.1 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.0 0.0 GO:0048867 ganglion mother cell fate determination(GO:0007402) stem cell fate determination(GO:0048867)
0.0 0.0 GO:0002125 maternal aggressive behavior(GO:0002125) regulation of prostaglandin biosynthetic process(GO:0031392) positive regulation of prostaglandin biosynthetic process(GO:0031394) regulation of unsaturated fatty acid biosynthetic process(GO:2001279) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.0 0.1 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0 1.0 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 0.2 GO:0030091 protein repair(GO:0030091)
0.0 0.9 GO:2000177 regulation of neural precursor cell proliferation(GO:2000177)
0.0 0.1 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.0 0.2 GO:0052696 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.0 0.6 GO:0016601 Rac protein signal transduction(GO:0016601)
0.0 0.1 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.5 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.0 0.1 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.2 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0 0.9 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 0.3 GO:0042135 neurotransmitter catabolic process(GO:0042135)
0.0 0.3 GO:0006833 water transport(GO:0006833)
0.0 0.0 GO:0090310 negative regulation of methylation-dependent chromatin silencing(GO:0090310)
0.0 0.0 GO:1900108 negative regulation of nodal signaling pathway(GO:1900108)
0.0 0.1 GO:0045591 positive regulation of regulatory T cell differentiation(GO:0045591)
0.0 0.1 GO:2000254 regulation of male germ cell proliferation(GO:2000254)
0.0 0.3 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 0.1 GO:0006874 cellular calcium ion homeostasis(GO:0006874)
0.0 0.1 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.0 0.0 GO:0042701 progesterone secretion(GO:0042701)
0.0 0.1 GO:0007369 gastrulation(GO:0007369)
0.0 0.4 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.5 GO:1903959 regulation of anion transmembrane transport(GO:1903959)
0.0 0.1 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0 0.1 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.0 0.2 GO:0090161 Golgi ribbon formation(GO:0090161)
0.0 0.2 GO:0051601 exocyst localization(GO:0051601)
0.0 0.1 GO:0045007 depurination(GO:0045007)
0.0 0.1 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.0 0.2 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0 0.1 GO:0010566 regulation of ketone biosynthetic process(GO:0010566)
0.0 0.1 GO:0010587 miRNA catabolic process(GO:0010587)
0.0 0.5 GO:0018279 peptidyl-asparagine modification(GO:0018196) protein N-linked glycosylation via asparagine(GO:0018279)
0.0 0.1 GO:0006600 creatine metabolic process(GO:0006600)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0005588 collagen type V trimer(GO:0005588)
0.4 1.6 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.3 2.3 GO:0097209 epidermal lamellar body(GO:0097209)
0.3 0.8 GO:0043511 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.2 1.7 GO:0036454 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.2 1.0 GO:0031262 Ndc80 complex(GO:0031262)
0.1 0.6 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.1 1.0 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.1 1.0 GO:0036449 microtubule minus-end(GO:0036449)
0.1 0.5 GO:0032279 asymmetric synapse(GO:0032279)
0.1 0.4 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.1 0.7 GO:0005579 membrane attack complex(GO:0005579)
0.1 1.4 GO:0042627 chylomicron(GO:0042627)
0.1 0.4 GO:0020018 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.1 1.3 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.1 0.3 GO:1990075 periciliary membrane compartment(GO:1990075)
0.1 0.5 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.1 0.2 GO:0043259 laminin-10 complex(GO:0043259) laminin-11 complex(GO:0043260)
0.1 0.4 GO:0036021 endolysosome lumen(GO:0036021)
0.1 0.8 GO:0005916 fascia adherens(GO:0005916)
0.0 0.4 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.1 GO:0043224 nuclear SCF ubiquitin ligase complex(GO:0043224)
0.0 0.7 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.6 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.2 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 6.8 GO:0005882 intermediate filament(GO:0005882)
0.0 1.6 GO:0005859 muscle myosin complex(GO:0005859)
0.0 0.4 GO:0070852 cell body fiber(GO:0070852)
0.0 0.2 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.0 0.3 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0 0.2 GO:0030678 mitochondrial ribonuclease P complex(GO:0030678)
0.0 0.1 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 0.6 GO:0032433 filopodium tip(GO:0032433)
0.0 0.2 GO:0072558 NLRP1 inflammasome complex(GO:0072558)
0.0 0.1 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.0 0.1 GO:0034686 integrin alphav-beta8 complex(GO:0034686)
0.0 0.4 GO:0008091 spectrin(GO:0008091)
0.0 0.6 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.0 0.7 GO:0031143 pseudopodium(GO:0031143)
0.0 0.2 GO:0019815 B cell receptor complex(GO:0019815)
0.0 0.3 GO:0000322 storage vacuole(GO:0000322) myelin sheath adaxonal region(GO:0035749)
0.0 0.3 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.5 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 1.2 GO:0001533 cornified envelope(GO:0001533)
0.0 2.6 GO:0072686 mitotic spindle(GO:0072686)
0.0 0.5 GO:0005861 troponin complex(GO:0005861)
0.0 0.9 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.2 GO:0034361 very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.0 0.1 GO:0000145 exocyst(GO:0000145)
0.0 1.1 GO:0031904 endosome lumen(GO:0031904)
0.0 0.1 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.0 0.2 GO:0030896 checkpoint clamp complex(GO:0030896)
0.0 0.3 GO:0032039 integrator complex(GO:0032039)
0.0 0.4 GO:0036020 endolysosome(GO:0036019) endolysosome membrane(GO:0036020)
0.0 0.1 GO:0031510 SUMO activating enzyme complex(GO:0031510)
0.0 0.3 GO:0031209 SCAR complex(GO:0031209)
0.0 0.7 GO:0030673 axolemma(GO:0030673)
0.0 0.1 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.4 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.2 GO:0032426 stereocilium tip(GO:0032426)
0.0 0.3 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.1 GO:0044305 calyx of Held(GO:0044305)
0.0 0.0 GO:0072517 viral factory(GO:0039713) cytoplasmic viral factory(GO:0039714) host cell viral assembly compartment(GO:0072517)
0.0 0.2 GO:0030914 SAGA complex(GO:0000124) STAGA complex(GO:0030914)
0.0 0.3 GO:0035748 myelin sheath abaxonal region(GO:0035748)
0.0 0.2 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.3 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.3 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.1 GO:0070761 pre-snoRNP complex(GO:0070761)
0.0 0.5 GO:0005921 gap junction(GO:0005921)
0.0 0.4 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.1 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.3 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.1 GO:0070081 clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.0 0.3 GO:0097342 ripoptosome(GO:0097342)
0.0 1.4 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 0.1 GO:0044327 dendritic spine head(GO:0044327)
0.0 0.0 GO:0032173 septin ring(GO:0005940) septin collar(GO:0032173)
0.0 0.3 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.2 GO:0044232 organelle membrane contact site(GO:0044232)
0.0 0.1 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.2 GO:0034709 methylosome(GO:0034709)
0.0 0.4 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.1 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.5 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 0.6 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.9 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 1.2 GO:0005604 basement membrane(GO:0005604)
0.0 0.4 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.3 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.0 GO:0033655 host cell cytoplasm(GO:0030430) host cell cytoplasm part(GO:0033655)
0.0 0.1 GO:0016602 CCAAT-binding factor complex(GO:0016602)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:0005150 interleukin-1, Type I receptor binding(GO:0005150)
0.3 0.8 GO:0070699 type II activin receptor binding(GO:0070699)
0.3 1.0 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.3 0.8 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.2 1.0 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
0.2 0.7 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.2 1.4 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.2 0.8 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.2 0.9 GO:0000298 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848)
0.1 0.6 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.1 1.8 GO:0030280 structural constituent of epidermis(GO:0030280)
0.1 0.3 GO:0004618 phosphoglycerate kinase activity(GO:0004618)
0.1 0.6 GO:0010465 nerve growth factor receptor activity(GO:0010465)
0.1 1.0 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.1 0.6 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.1 0.5 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.1 0.4 GO:0008410 CoA-transferase activity(GO:0008410)
0.1 0.5 GO:0070905 serine binding(GO:0070905)
0.1 0.3 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.1 2.0 GO:0019841 retinol binding(GO:0019841)
0.1 1.2 GO:0019957 C-C chemokine binding(GO:0019957)
0.1 0.4 GO:0047288 monosialoganglioside sialyltransferase activity(GO:0047288)
0.1 0.6 GO:0086075 gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075)
0.1 0.7 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.1 0.2 GO:0052593 tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
0.1 0.6 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.1 0.6 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.1 0.5 GO:0017018 myosin phosphatase activity(GO:0017018)
0.1 0.5 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.1 1.8 GO:0002162 dystroglycan binding(GO:0002162)
0.1 0.4 GO:0043515 kinetochore binding(GO:0043515)
0.1 0.3 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.1 0.3 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.1 1.0 GO:0045499 chemorepellent activity(GO:0045499)
0.1 0.6 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.1 0.2 GO:0032090 Pyrin domain binding(GO:0032090)
0.1 0.3 GO:0050309 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.1 8.8 GO:0031490 chromatin DNA binding(GO:0031490)
0.1 0.7 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.1 2.5 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.1 0.2 GO:1990259 protein-glutamine N-methyltransferase activity(GO:0036009) histone-glutamine methyltransferase activity(GO:1990259)
0.1 0.2 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.1 0.2 GO:0005119 smoothened binding(GO:0005119)
0.1 0.2 GO:0046538 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.1 0.4 GO:0050692 DBD domain binding(GO:0050692)
0.1 0.3 GO:0051373 FATZ binding(GO:0051373)
0.1 0.5 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.1 0.3 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.1 0.7 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.2 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0 1.2 GO:0043495 protein anchor(GO:0043495)
0.0 0.1 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.0 0.4 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.0 0.2 GO:0030226 apolipoprotein receptor activity(GO:0030226)
0.0 0.3 GO:0051032 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.0 0.2 GO:0051996 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.0 0.1 GO:0015403 thiamine uptake transmembrane transporter activity(GO:0015403)
0.0 0.1 GO:0015222 serotonin transmembrane transporter activity(GO:0015222)
0.0 0.4 GO:0042731 PH domain binding(GO:0042731)
0.0 3.9 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.3 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 0.3 GO:0016842 amidine-lyase activity(GO:0016842)
0.0 0.2 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.0 0.5 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.0 0.5 GO:0031014 troponin T binding(GO:0031014)
0.0 0.4 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.1 GO:0070283 lipoate synthase activity(GO:0016992) radical SAM enzyme activity(GO:0070283)
0.0 0.3 GO:0030021 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.0 0.2 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.0 0.0 GO:1903763 gap junction channel activity involved in cell communication by electrical coupling(GO:1903763)
0.0 0.2 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.0 0.7 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.2 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 0.4 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.2 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.0 0.5 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0 0.5 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.3 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 9.3 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.3 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 0.0 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.4 GO:0005549 odorant binding(GO:0005549)
0.0 0.1 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.6 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.7 GO:0000146 microfilament motor activity(GO:0000146)
0.0 0.9 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.9 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 1.9 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.2 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.9 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.2 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.2 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.2 GO:0032396 inhibitory MHC class I receptor activity(GO:0032396)
0.0 0.1 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.0 0.3 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.0 0.7 GO:0008483 transaminase activity(GO:0008483)
0.0 0.2 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.1 GO:0086062 voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
0.0 1.9 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.2 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.4 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.1 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.0 0.5 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.3 GO:0015250 water channel activity(GO:0015250)
0.0 0.2 GO:0046790 virion binding(GO:0046790)
0.0 0.1 GO:0016936 galactoside binding(GO:0016936)
0.0 0.1 GO:0001595 angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.0 0.1 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.0 0.1 GO:0004139 deoxyribose-phosphate aldolase activity(GO:0004139)
0.0 0.2 GO:0004340 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0 2.9 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.7 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.2 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.2 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0 0.1 GO:0004951 cholecystokinin receptor activity(GO:0004951)
0.0 0.4 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.4 GO:0070628 proteasome binding(GO:0070628)
0.0 0.2 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.0 0.3 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.0 0.5 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.1 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.0 0.6 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.1 GO:0016495 C-X3-C chemokine receptor activity(GO:0016495)
0.0 0.3 GO:0031957 fatty acid transporter activity(GO:0015245) very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.6 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.3 GO:0004180 carboxypeptidase activity(GO:0004180)
0.0 0.1 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.0 0.2 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.0 0.1 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 0.3 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.4 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.5 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.1 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.0 0.1 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.0 1.3 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.2 GO:0019956 chemokine binding(GO:0019956)
0.0 0.1 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
0.0 1.0 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.7 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.5 GO:0015301 anion:anion antiporter activity(GO:0015301)
0.0 0.1 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 0.0 GO:0031893 vasopressin receptor binding(GO:0031893)
0.0 0.3 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.3 GO:0045125 bioactive lipid receptor activity(GO:0045125)
0.0 0.2 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.3 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.1 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.0 0.2 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.0 0.1 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.0 0.1 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.0 0.1 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.1 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 0.1 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.0 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.0 GO:0000035 acyl binding(GO:0000035)
0.0 0.2 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.4 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.3 GO:0030507 spectrin binding(GO:0030507)
0.0 0.2 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.1 GO:0004467 long-chain fatty acid-CoA ligase activity(GO:0004467) decanoate--CoA ligase activity(GO:0102391)
0.0 0.1 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.1 GO:0004568 chitinase activity(GO:0004568)
0.0 0.3 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.2 GO:0070402 NADPH binding(GO:0070402)
0.0 0.6 GO:0016859 cis-trans isomerase activity(GO:0016859)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 ST_IL_13_PATHWAY Interleukin 13 (IL-13) Pathway
0.0 3.0 PID_ALPHA_SYNUCLEIN_PATHWAY Alpha-synuclein signaling
0.0 0.7 SA_B_CELL_RECEPTOR_COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 1.9 PID_SYNDECAN_1_PATHWAY Syndecan-1-mediated signaling events
0.0 1.9 PID_ER_NONGENOMIC_PATHWAY Plasma membrane estrogen receptor signaling
0.0 1.8 PID_IL1_PATHWAY IL1-mediated signaling events
0.0 0.4 PID_INSULIN_GLUCOSE_PATHWAY Insulin-mediated glucose transport
0.0 1.2 PID_RAS_PATHWAY Regulation of Ras family activation
0.0 0.4 PID_IL8_CXCR1_PATHWAY IL8- and CXCR1-mediated signaling events
0.0 1.1 ST_WNT_BETA_CATENIN_PATHWAY Wnt/beta-catenin Pathway
0.0 1.5 PID_AJDISS_2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.7 PID_NECTIN_PATHWAY Nectin adhesion pathway
0.0 0.5 PID_P38_MK2_PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.8 PID_ALK1_PATHWAY ALK1 signaling events
0.0 0.2 PID_PDGFRA_PATHWAY PDGFR-alpha signaling pathway
0.0 0.6 PID_NETRIN_PATHWAY Netrin-mediated signaling events
0.0 0.6 PID_NCADHERIN_PATHWAY N-cadherin signaling events
0.0 0.4 PID_IL27_PATHWAY IL27-mediated signaling events
0.0 1.3 PID_LKB1_PATHWAY LKB1 signaling events
0.0 0.6 PID_ERBB2_ERBB3_PATHWAY ErbB2/ErbB3 signaling events
0.0 0.4 PID_WNT_NONCANONICAL_PATHWAY Noncanonical Wnt signaling pathway
0.0 0.4 PID_TCPTP_PATHWAY Signaling events mediated by TCPTP
0.0 0.4 PID_ANGIOPOIETIN_RECEPTOR_PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.5 PID_RHODOPSIN_PATHWAY Visual signal transduction: Rods
0.0 4.2 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.3 PID_PDGFRB_PATHWAY PDGFR-beta signaling pathway
0.0 0.5 PID_KIT_PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.3 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling
0.0 0.6 PID_ATM_PATHWAY ATM pathway
0.0 0.7 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.1 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 1.4 REACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 0.9 REACTOME_TRAFFICKING_AND_PROCESSING_OF_ENDOSOMAL_TLR Genes involved in Trafficking and processing of endosomal TLR
0.1 0.8 REACTOME_GLYCOPROTEIN_HORMONES Genes involved in Glycoprotein hormones
0.0 3.4 REACTOME_STRIATED_MUSCLE_CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.9 REACTOME_IL_6_SIGNALING Genes involved in Interleukin-6 signaling
0.0 1.0 REACTOME_HDL_MEDIATED_LIPID_TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.2 REACTOME_PEPTIDE_HORMONE_BIOSYNTHESIS Genes involved in Peptide hormone biosynthesis
0.0 0.3 REACTOME_IKK_COMPLEX_RECRUITMENT_MEDIATED_BY_RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 2.0 REACTOME_IL1_SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.3 REACTOME_DOWNSTREAM_SIGNALING_EVENTS_OF_B_CELL_RECEPTOR_BCR Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)
0.0 1.1 REACTOME_REGULATION_OF_SIGNALING_BY_CBL Genes involved in Regulation of signaling by CBL
0.0 0.1 REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION_IN_TLR7_8_OR_9_SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 1.9 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.6 REACTOME_AMINE_DERIVED_HORMONES Genes involved in Amine-derived hormones
0.0 0.6 REACTOME_GAP_JUNCTION_ASSEMBLY Genes involved in Gap junction assembly
0.0 0.5 REACTOME_ENDOGENOUS_STEROLS Genes involved in Endogenous sterols
0.0 2.6 REACTOME_OLFACTORY_SIGNALING_PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 0.1 REACTOME_BINDING_AND_ENTRY_OF_HIV_VIRION Genes involved in Binding and entry of HIV virion
0.0 0.6 REACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.5 REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.7 REACTOME_AMINO_ACID_SYNTHESIS_AND_INTERCONVERSION_TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.3 REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.8 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.8 REACTOME_GPVI_MEDIATED_ACTIVATION_CASCADE Genes involved in GPVI-mediated activation cascade
0.0 0.5 REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.6 REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.2 REACTOME_RECEPTOR_LIGAND_BINDING_INITIATES_THE_SECOND_PROTEOLYTIC_CLEAVAGE_OF_NOTCH_RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.2 REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.4 REACTOME_ORGANIC_CATION_ANION_ZWITTERION_TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.2 REACTOME_SIGNALING_BY_FGFR3_MUTANTS Genes involved in Signaling by FGFR3 mutants
0.0 0.4 REACTOME_PROTEOLYTIC_CLEAVAGE_OF_SNARE_COMPLEX_PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.7 REACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.4 REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.3 REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.4 REACTOME_GLYCOGEN_BREAKDOWN_GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.3 REACTOME_DOWNREGULATION_OF_ERBB2_ERBB3_SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.5 REACTOME_MUSCLE_CONTRACTION Genes involved in Muscle contraction
0.0 0.6 REACTOME_HS_GAG_BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.3 REACTOME_SYNTHESIS_SECRETION_AND_DEACYLATION_OF_GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.4 REACTOME_BETA_DEFENSINS Genes involved in Beta defensins
0.0 0.9 REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.4 REACTOME_CHOLESTEROL_BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.6 REACTOME_AMYLOIDS Genes involved in Amyloids
0.0 0.3 REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.3 REACTOME_FANCONI_ANEMIA_PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.6 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.5 REACTOME_GLYCOLYSIS Genes involved in Glycolysis
0.0 0.1 REACTOME_REMOVAL_OF_THE_FLAP_INTERMEDIATE_FROM_THE_C_STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.6 REACTOME_GLUCOSE_TRANSPORT Genes involved in Glucose transport