Motif ID: MAX_TFEB

Z-value: 0.643

Transcription factors associated with MAX_TFEB:

Gene SymbolEntrez IDGene Name
MAX ENSG00000125952.14 MAX
TFEB ENSG00000112561.13 TFEB

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
TFEBhg19_v2_chr6_-_41701581_41701613-0.193.8e-01Click!
MAXhg19_v2_chr14_-_65569244_655694130.106.5e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of MAX_TFEB

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr17_-_7137582 1.381 ENST00000575756.1
ENST00000575458.1
DVL2

dishevelled segment polarity protein 2

chr12_+_50355647 1.347 ENST00000293599.6
AQP5
aquaporin 5
chr9_-_124976185 0.936 ENST00000464484.2
LHX6
LIM homeobox 6
chr17_-_7137857 0.854 ENST00000005340.5
DVL2
dishevelled segment polarity protein 2
chr9_-_124976154 0.746 ENST00000482062.1
LHX6
LIM homeobox 6
chr7_+_116593568 0.723 ENST00000446490.1
ST7
suppression of tumorigenicity 7
chrX_-_34675391 0.709 ENST00000275954.3
TMEM47
transmembrane protein 47
chr7_+_116593433 0.659 ENST00000323984.3
ENST00000393449.1
ST7

suppression of tumorigenicity 7

chr5_+_133706865 0.657 ENST00000265339.2
UBE2B
ubiquitin-conjugating enzyme E2B
chr2_-_133427767 0.624 ENST00000397463.2
LYPD1
LY6/PLAUR domain containing 1
chr19_-_10764509 0.580 ENST00000591501.1
ILF3-AS1
ILF3 antisense RNA 1 (head to head)
chr1_-_207119738 0.580 ENST00000356495.4
PIGR
polymeric immunoglobulin receptor
chr5_-_121413974 0.577 ENST00000231004.4
LOX
lysyl oxidase
chr6_+_123110465 0.563 ENST00000539041.1
SMPDL3A
sphingomyelin phosphodiesterase, acid-like 3A
chr6_-_80657292 0.545 ENST00000369816.4
ELOVL4
ELOVL fatty acid elongase 4
chr3_-_19988462 0.531 ENST00000344838.4
EFHB
EF-hand domain family, member B
chr6_+_123110302 0.523 ENST00000368440.4
SMPDL3A
sphingomyelin phosphodiesterase, acid-like 3A
chr7_+_155090271 0.520 ENST00000476756.1
INSIG1
insulin induced gene 1
chr7_+_106685079 0.517 ENST00000265717.4
PRKAR2B
protein kinase, cAMP-dependent, regulatory, type II, beta
chr1_-_154193009 0.500 ENST00000368518.1
ENST00000368519.1
ENST00000368521.5
C1orf43


chromosome 1 open reading frame 43


chr3_-_197686847 0.495 ENST00000265239.6
IQCG
IQ motif containing G
chr10_+_69644404 0.494 ENST00000212015.6
SIRT1
sirtuin 1
chr1_-_154193091 0.486 ENST00000362076.4
ENST00000350592.3
ENST00000368516.1
C1orf43


chromosome 1 open reading frame 43


chr9_-_90589586 0.480 ENST00000325303.8
ENST00000375883.3
CDK20

cyclin-dependent kinase 20

chr8_+_75896731 0.477 ENST00000262207.4
CRISPLD1
cysteine-rich secretory protein LCCL domain containing 1
chrX_+_30671476 0.475 ENST00000378946.3
ENST00000378943.3
ENST00000378945.3
ENST00000427190.1
ENST00000378941.3
GK




glycerol kinase




chr7_+_36429424 0.472 ENST00000396068.2
ANLN
anillin, actin binding protein
chr9_-_90589402 0.471 ENST00000375871.4
ENST00000605159.1
ENST00000336654.5
CDK20


cyclin-dependent kinase 20


chrX_+_55744166 0.468 ENST00000374941.4
ENST00000414239.1
RRAGB

Ras-related GTP binding B

chr15_+_45315302 0.455 ENST00000267814.9
SORD
sorbitol dehydrogenase
chr14_-_20923195 0.447 ENST00000206542.4
OSGEP
O-sialoglycoprotein endopeptidase
chr12_-_2986107 0.442 ENST00000359843.3
ENST00000342628.2
ENST00000361953.3
FOXM1


forkhead box M1


chr10_+_99344071 0.442 ENST00000370647.4
ENST00000370646.4
HOGA1

4-hydroxy-2-oxoglutarate aldolase 1

chr17_-_35969409 0.432 ENST00000394378.2
ENST00000585472.1
ENST00000591288.1
ENST00000502449.2
ENST00000345615.4
ENST00000346661.4
ENST00000585689.1
ENST00000339208.6
SYNRG







synergin, gamma







chr16_+_810728 0.429 ENST00000563941.1
ENST00000545450.2
ENST00000566549.1
MSLN


mesothelin


chrX_+_55744228 0.426 ENST00000262850.7
RRAGB
Ras-related GTP binding B
chr7_+_36429409 0.419 ENST00000265748.2
ANLN
anillin, actin binding protein
chr15_+_44084040 0.419 ENST00000249786.4
SERF2
small EDRK-rich factor 2
chr1_+_154193325 0.416 ENST00000428931.1
ENST00000441890.1
ENST00000271877.7
ENST00000412596.1
ENST00000368504.1
ENST00000437652.1
UBAP2L





ubiquitin associated protein 2-like





chr16_-_4897266 0.394 ENST00000591451.1
ENST00000436648.5
ENST00000381983.3
ENST00000588297.1
ENST00000321919.9
GLYR1




glyoxylate reductase 1 homolog (Arabidopsis)




chr1_-_204329013 0.379 ENST00000272203.3
ENST00000414478.1
PLEKHA6

pleckstrin homology domain containing, family A member 6

chr7_+_150065879 0.375 ENST00000478789.1
ENST00000397281.2
ENST00000444957.1
ENST00000466559.1
ENST00000489432.2
ENST00000475514.1
ENST00000482680.1
ENST00000488943.1
ENST00000518514.1
ZNF775
REPIN1







zinc finger protein 775
replication initiator 1







chr7_-_155089251 0.369 ENST00000609974.1
AC144652.1
AC144652.1
chr11_-_85779786 0.368 ENST00000356360.5
PICALM
phosphatidylinositol binding clathrin assembly protein
chr12_-_65153175 0.362 ENST00000543646.1
ENST00000542058.1
ENST00000258145.3
GNS


glucosamine (N-acetyl)-6-sulfatase


chr7_+_100464760 0.359 ENST00000200457.4
TRIP6
thyroid hormone receptor interactor 6
chr19_-_36545128 0.359 ENST00000538849.1
THAP8
THAP domain containing 8
chr19_+_1067271 0.349 ENST00000536472.1
ENST00000590214.1
HMHA1

histocompatibility (minor) HA-1

chr11_+_18344106 0.345 ENST00000534641.1
ENST00000525831.1
ENST00000265963.4
GTF2H1


general transcription factor IIH, polypeptide 1, 62kDa


chr2_-_10587897 0.343 ENST00000405333.1
ENST00000443218.1
ODC1

ornithine decarboxylase 1

chr10_-_90342947 0.340 ENST00000437752.1
ENST00000331772.4
RNLS

renalase, FAD-dependent amine oxidase

chr17_+_72270380 0.335 ENST00000582036.1
ENST00000307504.5
DNAI2

dynein, axonemal, intermediate chain 2

chr16_+_5083950 0.330 ENST00000588623.1
ALG1
ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase
chrX_+_102883887 0.320 ENST00000372625.3
ENST00000372624.3
TCEAL1

transcription elongation factor A (SII)-like 1

chrX_-_13835147 0.318 ENST00000493677.1
ENST00000355135.2
GPM6B

glycoprotein M6B

chr6_+_87865262 0.317 ENST00000369577.3
ENST00000518845.1
ENST00000339907.4
ENST00000496806.2
ZNF292



zinc finger protein 292



chr16_-_15736953 0.316 ENST00000548025.1
ENST00000551742.1
ENST00000602337.1
ENST00000344181.3
ENST00000396368.3
KIAA0430




KIAA0430




chr8_-_81083731 0.315 ENST00000379096.5
TPD52
tumor protein D52
chr20_+_37590942 0.314 ENST00000373325.2
ENST00000252011.3
ENST00000373323.4
DHX35


DEAH (Asp-Glu-Ala-His) box polypeptide 35


chrY_+_15016013 0.311 ENST00000360160.4
ENST00000454054.1
DDX3Y

DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked

chr1_-_3816779 0.311 ENST00000361605.3
C1orf174
chromosome 1 open reading frame 174
chr6_+_7590413 0.307 ENST00000342415.5
SNRNP48
small nuclear ribonucleoprotein 48kDa (U11/U12)
chr19_-_11545920 0.306 ENST00000356392.4
ENST00000591179.1
CCDC151

coiled-coil domain containing 151

chr14_-_75536182 0.306 ENST00000555463.1
ACYP1
acylphosphatase 1, erythrocyte (common) type
chr12_+_122356488 0.303 ENST00000397454.2
WDR66
WD repeat domain 66
chr19_-_49137762 0.301 ENST00000593500.1
DBP
D site of albumin promoter (albumin D-box) binding protein
chr7_+_44646162 0.297 ENST00000439616.2
OGDH
oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
chrX_+_108780347 0.297 ENST00000372103.1
NXT2
nuclear transport factor 2-like export factor 2
chr14_+_96858433 0.295 ENST00000267584.4
AK7
adenylate kinase 7
chr11_+_18343800 0.292 ENST00000453096.2
GTF2H1
general transcription factor IIH, polypeptide 1, 62kDa
chr20_+_47538357 0.291 ENST00000371917.4
ARFGEF2
ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
chr18_-_46987000 0.291 ENST00000442713.2
ENST00000269445.6
DYM

dymeclin

chr19_+_1067144 0.291 ENST00000313093.2
HMHA1
histocompatibility (minor) HA-1
chr15_+_82555125 0.291 ENST00000566205.1
ENST00000339465.5
ENST00000569120.1
ENST00000566861.1
FAM154B



family with sequence similarity 154, member B



chr11_+_65479702 0.287 ENST00000530446.1
ENST00000534104.1
ENST00000530605.1
ENST00000528198.1
ENST00000531880.1
ENST00000534650.1
KAT5





K(lysine) acetyltransferase 5





chrX_+_102840408 0.286 ENST00000468024.1
ENST00000472484.1
ENST00000415568.2
ENST00000490644.1
ENST00000459722.1
ENST00000472745.1
ENST00000494801.1
ENST00000434216.2
ENST00000425011.1
TCEAL4








transcription elongation factor A (SII)-like 4








chr1_+_222885884 0.279 ENST00000340934.5
BROX
BRO1 domain and CAAX motif containing
chr18_-_3247084 0.274 ENST00000609924.1
RP13-270P17.3
RP13-270P17.3
chr2_-_220108309 0.274 ENST00000409640.1
GLB1L
galactosidase, beta 1-like
chr1_-_42921915 0.274 ENST00000372565.3
ENST00000433602.2
ZMYND12

zinc finger, MYND-type containing 12

chr21_-_36421401 0.272 ENST00000486278.2
RUNX1
runt-related transcription factor 1
chr16_+_70148230 0.271 ENST00000398122.3
ENST00000568530.1
PDPR

pyruvate dehydrogenase phosphatase regulatory subunit

chr17_+_72270429 0.270 ENST00000311014.6
DNAI2
dynein, axonemal, intermediate chain 2
chr11_+_65479462 0.269 ENST00000377046.3
ENST00000352980.4
ENST00000341318.4
KAT5


K(lysine) acetyltransferase 5


chr14_+_77564440 0.266 ENST00000361786.2
ENST00000555437.1
ENST00000555611.1
ENST00000554658.1
KIAA1737



CLOCK-interacting pacemaker



chr19_+_1067492 0.266 ENST00000586866.1
HMHA1
histocompatibility (minor) HA-1
chr2_+_46926326 0.265 ENST00000394861.2
SOCS5
suppressor of cytokine signaling 5
chrX_+_102883620 0.263 ENST00000372626.3
TCEAL1
transcription elongation factor A (SII)-like 1
chr14_+_45553296 0.263 ENST00000355765.6
ENST00000553605.1
PRPF39

pre-mRNA processing factor 39

chr8_+_42128812 0.262 ENST00000520810.1
ENST00000416505.2
ENST00000519735.1
ENST00000520835.1
ENST00000379708.3
IKBKB




inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta




chr1_-_51425902 0.262 ENST00000396153.2
FAF1
Fas (TNFRSF6) associated factor 1
chr5_+_43603229 0.259 ENST00000344920.4
ENST00000512996.2
NNT

nicotinamide nucleotide transhydrogenase

chr4_-_47465666 0.258 ENST00000381571.4
COMMD8
COMM domain containing 8
chr11_+_7534999 0.258 ENST00000528947.1
ENST00000299492.4
PPFIBP2

PTPRF interacting protein, binding protein 2 (liprin beta 2)

chr16_+_84178874 0.257 ENST00000378553.5
DNAAF1
dynein, axonemal, assembly factor 1
chrX_+_108779870 0.256 ENST00000372107.1
NXT2
nuclear transport factor 2-like export factor 2
chr12_+_28343365 0.256 ENST00000545336.1
CCDC91
coiled-coil domain containing 91
chr6_-_158589259 0.254 ENST00000367101.1
ENST00000367104.3
ENST00000367102.2
SERAC1


serine active site containing 1


chr1_-_68962805 0.254 ENST00000370966.5
DEPDC1
DEP domain containing 1
chrX_+_100663243 0.252 ENST00000316594.5
HNRNPH2
heterogeneous nuclear ribonucleoprotein H2 (H')
chr6_-_144329531 0.252 ENST00000429150.1
ENST00000392309.1
ENST00000416623.1
ENST00000392307.1
PLAGL1



pleiomorphic adenoma gene-like 1



chr12_+_133613878 0.251 ENST00000392319.2
ENST00000543758.1
ZNF84

zinc finger protein 84

chr6_+_42018614 0.250 ENST00000465926.1
ENST00000482432.1
TAF8

TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 43kDa

chr2_+_46926048 0.250 ENST00000306503.5
SOCS5
suppressor of cytokine signaling 5
chr11_+_63706444 0.249 ENST00000377793.4
ENST00000456907.2
ENST00000539656.1
NAA40


N(alpha)-acetyltransferase 40, NatD catalytic subunit


chr12_+_57624085 0.247 ENST00000553474.1
SHMT2
serine hydroxymethyltransferase 2 (mitochondrial)
chr19_+_39903185 0.246 ENST00000409794.3
PLEKHG2
pleckstrin homology domain containing, family G (with RhoGef domain) member 2
chr12_-_122750957 0.246 ENST00000451053.2
VPS33A
vacuolar protein sorting 33 homolog A (S. cerevisiae)
chr7_-_56118981 0.245 ENST00000419984.2
ENST00000413218.1
ENST00000424596.1
PSPH


phosphoserine phosphatase


chr1_-_26233423 0.245 ENST00000357865.2
STMN1
stathmin 1
chr3_-_17783990 0.242 ENST00000429383.4
ENST00000446863.1
ENST00000414349.1
ENST00000428355.1
ENST00000425944.1
ENST00000445294.1
ENST00000444471.1
ENST00000415814.2
TBC1D5







TBC1 domain family, member 5







chr2_-_148778323 0.242 ENST00000440042.1
ENST00000535373.1
ENST00000540442.1
ENST00000536575.1
ORC4



origin recognition complex, subunit 4



chr4_+_15480828 0.240 ENST00000389652.5
CC2D2A
coiled-coil and C2 domain containing 2A
chr1_-_68962782 0.240 ENST00000456315.2
DEPDC1
DEP domain containing 1
chr19_-_48018203 0.239 ENST00000595227.1
ENST00000593761.1
ENST00000263354.3
NAPA


N-ethylmaleimide-sensitive factor attachment protein, alpha


chr9_+_74526384 0.239 ENST00000334731.2
ENST00000377031.3
C9orf85

chromosome 9 open reading frame 85

chr9_-_97356075 0.239 ENST00000375337.3
FBP2
fructose-1,6-bisphosphatase 2
chr9_+_6757634 0.238 ENST00000543771.1
ENST00000401787.3
ENST00000381306.3
ENST00000381309.3
KDM4C



lysine (K)-specific demethylase 4C



chr11_-_85779971 0.238 ENST00000393346.3
PICALM
phosphatidylinositol binding clathrin assembly protein
chr19_+_7587491 0.238 ENST00000264079.6
MCOLN1
mucolipin 1
chr10_+_101542462 0.238 ENST00000370449.4
ENST00000370434.1
ABCC2

ATP-binding cassette, sub-family C (CFTR/MRP), member 2

chr5_-_158636512 0.237 ENST00000424310.2
RNF145
ring finger protein 145
chr16_+_699319 0.235 ENST00000549091.1
ENST00000293879.4
WDR90

WD repeat domain 90

chr15_-_50978965 0.235 ENST00000560955.1
ENST00000313478.7
TRPM7

transient receptor potential cation channel, subfamily M, member 7

chr16_-_67517716 0.234 ENST00000290953.2
AGRP
agouti related protein homolog (mouse)
chr19_-_49137790 0.234 ENST00000599385.1
DBP
D site of albumin promoter (albumin D-box) binding protein
chr7_-_56119156 0.233 ENST00000421312.1
ENST00000416592.1
PSPH

phosphoserine phosphatase

chr20_+_48552908 0.233 ENST00000244061.2
RNF114
ring finger protein 114
chr7_+_130126012 0.233 ENST00000341441.5
MEST
mesoderm specific transcript
chr7_-_122526499 0.233 ENST00000412584.2
CADPS2
Ca++-dependent secretion activator 2
chr11_+_120894781 0.233 ENST00000529397.1
ENST00000528512.1
ENST00000422003.2
TBCEL


tubulin folding cofactor E-like


chr10_-_61666267 0.230 ENST00000263102.6
CCDC6
coiled-coil domain containing 6
chr21_-_36421626 0.226 ENST00000300305.3
RUNX1
runt-related transcription factor 1
chr12_+_2986359 0.225 ENST00000538636.1
ENST00000461997.2
ENST00000489288.2
ENST00000366285.2
ENST00000538700.1
RHNO1




RAD9-HUS1-RAD1 interacting nuclear orphan 1




chr2_-_176866978 0.225 ENST00000392540.2
ENST00000409660.1
ENST00000544803.1
ENST00000272748.4
KIAA1715



KIAA1715



chrX_+_102469997 0.225 ENST00000372695.5
ENST00000372691.3
BEX4

brain expressed, X-linked 4

chr18_+_21083437 0.225 ENST00000269221.3
ENST00000590868.1
ENST00000592119.1
C18orf8


chromosome 18 open reading frame 8


chr2_-_26101374 0.221 ENST00000435504.4
ASXL2
additional sex combs like 2 (Drosophila)
chr22_+_31003133 0.220 ENST00000405742.3
TCN2
transcobalamin II
chr13_-_96296944 0.219 ENST00000361396.2
ENST00000376829.2
DZIP1

DAZ interacting zinc finger protein 1

chr6_-_163834852 0.218 ENST00000604200.1
CAHM
colon adenocarcinoma hypermethylated (non-protein coding)
chr15_+_44084503 0.218 ENST00000409960.2
ENST00000409646.1
ENST00000594896.1
ENST00000339624.5
ENST00000409291.1
ENST00000402131.1
ENST00000403425.1
ENST00000430901.1
SERF2







small EDRK-rich factor 2







chr6_+_160221293 0.218 ENST00000610273.1
ENST00000392167.3
PNLDC1

poly(A)-specific ribonuclease (PARN)-like domain containing 1

chr19_-_12833361 0.217 ENST00000592287.1
TNPO2
transportin 2
chr9_+_133454943 0.216 ENST00000319725.9
FUBP3
far upstream element (FUSE) binding protein 3
chr14_-_54955721 0.216 ENST00000554908.1
GMFB
glia maturation factor, beta
chr21_-_36421535 0.215 ENST00000416754.1
ENST00000437180.1
ENST00000455571.1
RUNX1


runt-related transcription factor 1


chr7_+_116593292 0.214 ENST00000393446.2
ENST00000265437.5
ENST00000393451.3
ST7


suppression of tumorigenicity 7


chr14_-_35591433 0.214 ENST00000261475.5
ENST00000555644.1
PPP2R3C

protein phosphatase 2, regulatory subunit B'', gamma

chr8_-_41909496 0.213 ENST00000265713.2
ENST00000406337.1
ENST00000396930.3
ENST00000485568.1
ENST00000426524.1
KAT6A




K(lysine) acetyltransferase 6A




chr17_-_47841485 0.210 ENST00000506156.1
ENST00000240364.2
FAM117A

family with sequence similarity 117, member A

chr9_+_117373486 0.209 ENST00000288502.4
ENST00000374049.4
C9orf91

chromosome 9 open reading frame 91

chr1_+_100315613 0.208 ENST00000361915.3
AGL
amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
chr19_-_46974664 0.206 ENST00000438932.2
PNMAL1
paraneoplastic Ma antigen family-like 1
chr3_+_158519654 0.206 ENST00000415822.2
ENST00000392813.4
ENST00000264266.8
MFSD1


major facilitator superfamily domain containing 1


chr6_-_109703600 0.206 ENST00000512821.1
CD164
CD164 molecule, sialomucin
chr7_+_130126165 0.205 ENST00000427521.1
ENST00000416162.2
ENST00000378576.4
MEST


mesoderm specific transcript


chr3_-_45883558 0.204 ENST00000445698.1
ENST00000296135.6
LZTFL1

leucine zipper transcription factor-like 1

chrX_+_134654540 0.204 ENST00000370752.4
DDX26B
DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B
chrX_-_102510126 0.203 ENST00000372685.3
TCEAL8
transcription elongation factor A (SII)-like 8
chrX_-_102510045 0.202 ENST00000360000.4
TCEAL8
transcription elongation factor A (SII)-like 8
chr2_-_148778258 0.202 ENST00000392857.5
ENST00000457954.1
ENST00000392858.1
ENST00000542387.1
ORC4



origin recognition complex, subunit 4



chr5_+_43602750 0.201 ENST00000505678.2
ENST00000512422.1
ENST00000264663.5
NNT


nicotinamide nucleotide transhydrogenase


chr3_-_46904946 0.198 ENST00000292327.4
MYL3
myosin, light chain 3, alkali; ventricular, skeletal, slow
chr3_+_112280857 0.198 ENST00000492406.1
ENST00000468642.1
SLC35A5

solute carrier family 35, member A5

chr3_-_195163803 0.198 ENST00000326793.6
ACAP2
ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
chr19_-_45004556 0.197 ENST00000587047.1
ENST00000391956.4
ENST00000221327.4
ENST00000586637.1
ENST00000591064.1
ENST00000592529.1
ZNF180





zinc finger protein 180





chr12_+_57624119 0.197 ENST00000555773.1
ENST00000554975.1
ENST00000449049.3
ENST00000393827.4
SHMT2



serine hydroxymethyltransferase 2 (mitochondrial)



chrX_-_13835461 0.196 ENST00000316715.4
ENST00000356942.5
GPM6B

glycoprotein M6B

chr19_-_46974741 0.196 ENST00000313683.10
ENST00000602246.1
PNMAL1

paraneoplastic Ma antigen family-like 1

chr16_+_69984810 0.196 ENST00000393701.2
ENST00000568461.1
CLEC18A

C-type lectin domain family 18, member A

chr18_+_9136758 0.196 ENST00000383440.2
ENST00000262126.4
ENST00000577992.1
ANKRD12


ankyrin repeat domain 12


chr9_+_92219919 0.195 ENST00000252506.6
ENST00000375769.1
GADD45G

growth arrest and DNA-damage-inducible, gamma

chr17_-_34890709 0.192 ENST00000544606.1
MYO19
myosin XIX
chr12_+_53662110 0.192 ENST00000552462.1
ESPL1
extra spindle pole bodies homolog 1 (S. cerevisiae)
chr4_+_39184024 0.192 ENST00000399820.3
ENST00000509560.1
ENST00000512112.1
ENST00000288634.7
ENST00000506503.1
WDR19




WD repeat domain 19




chr4_-_99850243 0.192 ENST00000280892.6
ENST00000511644.1
ENST00000504432.1
ENST00000505992.1
EIF4E



eukaryotic translation initiation factor 4E



chr1_-_207095324 0.191 ENST00000530505.1
ENST00000367091.3
ENST00000442471.2
FAIM3


Fas apoptotic inhibitory molecule 3


chr22_+_31002779 0.190 ENST00000215838.3
TCN2
transcobalamin II
chr1_-_109656439 0.188 ENST00000369949.4
C1orf194
chromosome 1 open reading frame 194
chr19_+_6464502 0.188 ENST00000308243.7
CRB3
crumbs homolog 3 (Drosophila)
chr6_-_43337180 0.188 ENST00000318149.3
ENST00000361428.2
ZNF318

zinc finger protein 318

chr21_-_38445470 0.187 ENST00000399098.1
PIGP
phosphatidylinositol glycan anchor biosynthesis, class P
chr6_-_31864977 0.187 ENST00000395728.3
ENST00000375528.4
EHMT2

euchromatic histone-lysine N-methyltransferase 2

chr2_-_26101314 0.186 ENST00000336112.4
ENST00000272341.4
ASXL2

additional sex combs like 2 (Drosophila)

chr10_-_32217717 0.186 ENST00000396144.4
ENST00000375245.4
ENST00000344936.2
ENST00000375250.5
ARHGAP12



Rho GTPase activating protein 12



chr7_-_42951509 0.185 ENST00000438029.1
ENST00000432637.1
ENST00000447342.1
ENST00000431882.2
ENST00000350427.4
ENST00000425683.1
C7orf25





chromosome 7 open reading frame 25





chr1_-_166845515 0.185 ENST00000367874.4
TADA1
transcriptional adaptor 1
chr1_-_231376836 0.184 ENST00000451322.1
C1orf131
chromosome 1 open reading frame 131
chr12_+_72148614 0.183 ENST00000261263.3
RAB21
RAB21, member RAS oncogene family
chr8_+_133787586 0.182 ENST00000395379.1
ENST00000395386.2
ENST00000337920.4
PHF20L1


PHD finger protein 20-like 1


chr17_+_42148225 0.182 ENST00000591696.1
G6PC3
glucose 6 phosphatase, catalytic, 3
chr1_-_9129895 0.181 ENST00000473209.1
SLC2A5
solute carrier family 2 (facilitated glucose/fructose transporter), member 5
chr5_-_68628543 0.181 ENST00000396496.2
ENST00000511257.1
ENST00000383374.2
CCDC125


coiled-coil domain containing 125


chr11_+_63606477 0.181 ENST00000508192.1
ENST00000361128.5
MARK2

MAP/microtubule affinity-regulating kinase 2

chr1_-_31845914 0.181 ENST00000373713.2
FABP3
fatty acid binding protein 3, muscle and heart (mammary-derived growth inhibitor)
chr8_-_75233563 0.181 ENST00000342232.4
JPH1
junctophilin 1
chr3_+_183967409 0.181 ENST00000324557.4
ENST00000402825.3
ECE2

endothelin converting enzyme 2

chr8_-_124553437 0.180 ENST00000517956.1
ENST00000443022.2
FBXO32

F-box protein 32

chr3_-_46904918 0.179 ENST00000395869.1
MYL3
myosin, light chain 3, alkali; ventricular, skeletal, slow

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.2 GO:0014022 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.3 0.9 GO:1904170 regulation of bleb assembly(GO:1904170) positive regulation of bleb assembly(GO:1904172)
0.3 1.3 GO:0015670 carbon dioxide transport(GO:0015670)
0.3 0.8 GO:0010845 positive regulation of reciprocal meiotic recombination(GO:0010845)
0.2 0.5 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.2 0.5 GO:0051097 negative regulation of helicase activity(GO:0051097)
0.2 0.5 GO:0046167 glycerol-3-phosphate biosynthetic process(GO:0046167)
0.2 0.5 GO:0006059 hexitol metabolic process(GO:0006059)
0.1 0.4 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.1 0.4 GO:0009436 glyoxylate catabolic process(GO:0009436)
0.1 0.7 GO:0002415 immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
0.1 1.0 GO:1902963 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.1 0.5 GO:0006218 uridine catabolic process(GO:0006218)
0.1 1.7 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.1 0.1 GO:0032227 negative regulation of synaptic transmission, dopaminergic(GO:0032227)
0.1 1.1 GO:1990253 cellular response to leucine starvation(GO:1990253)
0.1 0.5 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
0.1 0.8 GO:0019264 glycine biosynthetic process from serine(GO:0019264)
0.1 0.5 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.1 0.5 GO:0061034 olfactory bulb mitral cell layer development(GO:0061034)
0.1 0.5 GO:0006740 NADPH regeneration(GO:0006740)
0.1 0.6 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.1 0.8 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 0.4 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.1 0.4 GO:1902544 regulation of DNA N-glycosylase activity(GO:1902544)
0.1 1.1 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.1 0.3 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.1 0.2 GO:0006258 UDP-glucose catabolic process(GO:0006258)
0.1 0.1 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.1 0.2 GO:0006864 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
0.1 0.2 GO:0035494 SNARE complex disassembly(GO:0035494)
0.1 0.2 GO:0050787 antibiotic metabolic process(GO:0016999) detoxification of mercury ion(GO:0050787)
0.1 0.2 GO:0016340 calcium-dependent cell-matrix adhesion(GO:0016340)
0.1 0.3 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
0.1 0.2 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.1 0.5 GO:0097338 response to clozapine(GO:0097338)
0.1 0.4 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.1 0.6 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.1 0.2 GO:1903568 negative regulation of protein localization to cilium(GO:1903565) regulation of protein localization to ciliary membrane(GO:1903567) negative regulation of protein localization to ciliary membrane(GO:1903568)
0.1 0.2 GO:0044209 AMP salvage(GO:0044209)
0.1 0.3 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.1 0.5 GO:0007288 sperm axoneme assembly(GO:0007288)
0.1 0.1 GO:0031291 Ran protein signal transduction(GO:0031291)
0.1 1.3 GO:0036158 outer dynein arm assembly(GO:0036158)
0.1 0.1 GO:0006286 base-excision repair, base-free sugar-phosphate removal(GO:0006286)
0.1 0.4 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.1 0.2 GO:2001245 regulation of phosphatidylcholine biosynthetic process(GO:2001245)
0.1 0.3 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.1 0.2 GO:0005986 sucrose biosynthetic process(GO:0005986)
0.1 0.2 GO:0070318 positive regulation of G0 to G1 transition(GO:0070318)
0.1 0.3 GO:0021997 neural plate axis specification(GO:0021997)
0.1 0.2 GO:1901895 negative regulation of calcium-transporting ATPase activity(GO:1901895)
0.1 0.2 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.1 0.3 GO:0046985 positive regulation of hemoglobin biosynthetic process(GO:0046985)
0.1 0.7 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 0.5 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.1 0.2 GO:0002276 basophil activation involved in immune response(GO:0002276)
0.0 0.2 GO:0060830 ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
0.0 0.2 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.0 0.2 GO:0046452 dihydrofolate metabolic process(GO:0046452)
0.0 0.2 GO:2000619 negative regulation of histone H4-K16 acetylation(GO:2000619)
0.0 0.3 GO:0033183 negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315)
0.0 0.2 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.0 0.1 GO:0048203 vesicle targeting, trans-Golgi to endosome(GO:0048203)
0.0 0.5 GO:0006824 cobalt ion transport(GO:0006824)
0.0 0.1 GO:0060399 positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.0 0.2 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.0 0.1 GO:0044771 meiotic cell cycle phase transition(GO:0044771) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.0 0.1 GO:0060086 circadian temperature homeostasis(GO:0060086) positive regulation of bile acid biosynthetic process(GO:0070859) positive regulation of bile acid metabolic process(GO:1904253)
0.0 0.5 GO:2000781 positive regulation of double-strand break repair(GO:2000781)
0.0 0.2 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.0 0.3 GO:1990504 dense core granule exocytosis(GO:1990504)
0.0 0.2 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.0 0.4 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.0 0.1 GO:0006210 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.0 0.2 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.0 0.1 GO:2000705 histone H3-T6 phosphorylation(GO:0035408) dense core granule biogenesis(GO:0061110) regulation of dense core granule biogenesis(GO:2000705)
0.0 0.3 GO:1901525 negative regulation of macromitophagy(GO:1901525)
0.0 0.3 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.1 GO:0032240 negative regulation of nucleobase-containing compound transport(GO:0032240) negative regulation of RNA export from nucleus(GO:0046832)
0.0 0.1 GO:0015883 FAD transport(GO:0015883) FAD transmembrane transport(GO:0035350)
0.0 0.3 GO:0045716 positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716)
0.0 0.1 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037)
0.0 0.2 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.0 0.4 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 0.2 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.0 0.2 GO:0071477 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.0 0.1 GO:0000957 mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
0.0 0.1 GO:1990569 UDP-N-acetylglucosamine transport(GO:0015788) UDP-N-acetylglucosamine transmembrane transport(GO:1990569)
0.0 0.1 GO:0048633 positive regulation of skeletal muscle tissue growth(GO:0048633)
0.0 0.1 GO:0048254 snoRNA localization(GO:0048254)
0.0 0.1 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.0 0.1 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.0 0.1 GO:1903542 negative regulation of exosomal secretion(GO:1903542)
0.0 0.1 GO:1903674 regulation of cap-dependent translational initiation(GO:1903674) positive regulation of cap-dependent translational initiation(GO:1903676)
0.0 0.6 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.1 GO:1903564 regulation of protein localization to cilium(GO:1903564)
0.0 0.1 GO:0021798 forebrain dorsal/ventral pattern formation(GO:0021798)
0.0 0.2 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.0 0.6 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.0 0.2 GO:0072592 oxygen metabolic process(GO:0072592)
0.0 0.2 GO:0002759 regulation of antimicrobial humoral response(GO:0002759)
0.0 0.1 GO:1902725 negative regulation of satellite cell differentiation(GO:1902725)
0.0 0.2 GO:0061470 T follicular helper cell differentiation(GO:0061470)
0.0 0.1 GO:0015960 diadenosine polyphosphate biosynthetic process(GO:0015960) diadenosine tetraphosphate metabolic process(GO:0015965) diadenosine tetraphosphate biosynthetic process(GO:0015966) cytosine metabolic process(GO:0019858)
0.0 0.2 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.0 0.1 GO:0098927 vesicle-mediated transport between endosomal compartments(GO:0098927)
0.0 0.1 GO:1990168 protein K33-linked deubiquitination(GO:1990168)
0.0 0.2 GO:0098704 fructose transport(GO:0015755) fructose import(GO:0032445) carbohydrate import into cell(GO:0097319) carbohydrate import across plasma membrane(GO:0098704) fructose import across plasma membrane(GO:1990539)
0.0 0.4 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.4 GO:0035360 positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360)
0.0 0.3 GO:0015074 DNA integration(GO:0015074)
0.0 0.6 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.1 GO:0036229 glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803)
0.0 0.1 GO:0032474 otolith morphogenesis(GO:0032474)
0.0 0.4 GO:0050812 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812)
0.0 0.1 GO:0090298 base-excision repair, DNA ligation(GO:0006288) negative regulation of mitochondrial DNA replication(GO:0090298) negative regulation of mitochondrial DNA metabolic process(GO:1901859)
0.0 0.8 GO:2000810 regulation of bicellular tight junction assembly(GO:2000810)
0.0 0.2 GO:0010825 positive regulation of centrosome duplication(GO:0010825)
0.0 0.1 GO:0000472 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000472) rRNA 5'-end processing(GO:0000967) ncRNA 5'-end processing(GO:0034471)
0.0 0.1 GO:0009181 purine nucleoside diphosphate catabolic process(GO:0009137) purine ribonucleoside diphosphate catabolic process(GO:0009181)
0.0 0.1 GO:0044565 dendritic cell proliferation(GO:0044565)
0.0 0.1 GO:0060023 soft palate development(GO:0060023)
0.0 0.0 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.0 0.1 GO:1904263 positive regulation of TORC1 signaling(GO:1904263)
0.0 0.1 GO:2000110 negative regulation of macrophage apoptotic process(GO:2000110)
0.0 0.1 GO:0051088 PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.0 0.0 GO:0055073 cadmium ion homeostasis(GO:0055073)
0.0 0.3 GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.0 0.1 GO:0045446 endothelial cell differentiation(GO:0045446)
0.0 0.7 GO:1903077 negative regulation of protein localization to plasma membrane(GO:1903077) negative regulation of protein localization to cell periphery(GO:1904376)
0.0 0.1 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.0 0.1 GO:1903232 melanosome assembly(GO:1903232)
0.0 0.2 GO:1990034 cellular response to corticosterone stimulus(GO:0071386) calcium ion export from cell(GO:1990034)
0.0 0.1 GO:1904617 negative regulation of actin filament binding(GO:1904530) negative regulation of actin binding(GO:1904617)
0.0 0.1 GO:0006344 maintenance of chromatin silencing(GO:0006344)
0.0 0.1 GO:0070295 renal water absorption(GO:0070295)
0.0 0.3 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.1 GO:2001295 malonyl-CoA biosynthetic process(GO:2001295)
0.0 0.1 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732) translation reinitiation(GO:0002188)
0.0 0.2 GO:0014877 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.0 0.1 GO:2000276 negative regulation of oxidative phosphorylation uncoupler activity(GO:2000276)
0.0 0.0 GO:0005997 xylulose metabolic process(GO:0005997)
0.0 0.2 GO:1905097 regulation of guanyl-nucleotide exchange factor activity(GO:1905097)
0.0 0.1 GO:0051924 regulation of calcium ion transport(GO:0051924)
0.0 0.1 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.1 GO:0060648 mammary gland bud morphogenesis(GO:0060648)
0.0 0.1 GO:0002572 pro-T cell differentiation(GO:0002572)
0.0 0.0 GO:0043457 regulation of cellular respiration(GO:0043457)
0.0 0.1 GO:0072711 cellular response to hydroxyurea(GO:0072711)
0.0 0.3 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 0.1 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.0 0.0 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.0 0.1 GO:1904764 negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764)
0.0 0.6 GO:0000729 DNA double-strand break processing(GO:0000729)
0.0 0.3 GO:0018027 peptidyl-lysine dimethylation(GO:0018027)
0.0 0.1 GO:0019470 4-hydroxyproline catabolic process(GO:0019470)
0.0 0.1 GO:0071169 establishment of protein localization to chromatin(GO:0071169)
0.0 0.1 GO:0009233 menaquinone metabolic process(GO:0009233)
0.0 0.8 GO:1904031 positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.0 0.0 GO:0060994 regulation of transcription from RNA polymerase II promoter involved in kidney development(GO:0060994)
0.0 0.3 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.0 0.1 GO:1900224 positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224)
0.0 0.4 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.1 GO:0009052 D-ribose metabolic process(GO:0006014) pentose-phosphate shunt, non-oxidative branch(GO:0009052)
0.0 0.1 GO:1903301 positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.0 0.0 GO:0070902 mitochondrial tRNA pseudouridine synthesis(GO:0070902)
0.0 0.3 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 0.1 GO:0051140 regulation of NK T cell proliferation(GO:0051140) positive regulation of NK T cell proliferation(GO:0051142)
0.0 0.1 GO:0006668 sphinganine-1-phosphate metabolic process(GO:0006668)
0.0 0.1 GO:1904327 protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.0 0.0 GO:0044205 'de novo' UMP biosynthetic process(GO:0044205)
0.0 0.1 GO:2000857 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.0 0.0 GO:1903061 positive regulation of protein lipidation(GO:1903061)
0.0 0.1 GO:1904153 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.0 0.0 GO:0048631 regulation of skeletal muscle tissue growth(GO:0048631)
0.0 0.2 GO:1904352 positive regulation of protein catabolic process in the vacuole(GO:1904352)
0.0 0.1 GO:0051182 coenzyme transport(GO:0051182)
0.0 0.1 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.0 0.0 GO:0006433 prolyl-tRNA aminoacylation(GO:0006433)
0.0 0.1 GO:0003430 growth plate cartilage chondrocyte growth(GO:0003430) Harderian gland development(GO:0070384)
0.0 0.2 GO:0006670 sphingosine metabolic process(GO:0006670)
0.0 0.3 GO:0002021 response to dietary excess(GO:0002021)
0.0 0.1 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.0 0.0 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)
0.0 0.1 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.0 0.1 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
0.0 0.1 GO:0009236 cobalamin biosynthetic process(GO:0009236)
0.0 0.0 GO:0060435 bronchiole development(GO:0060435)
0.0 0.5 GO:0090140 regulation of mitochondrial fission(GO:0090140)
0.0 0.2 GO:0046321 positive regulation of fatty acid oxidation(GO:0046321)
0.0 0.0 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.0 0.0 GO:0034059 response to anoxia(GO:0034059)
0.0 0.1 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.0 0.2 GO:0030183 B cell differentiation(GO:0030183)
0.0 0.5 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.0 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
0.0 0.1 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
0.0 0.1 GO:0071874 response to norepinephrine(GO:0071873) cellular response to norepinephrine stimulus(GO:0071874)
0.0 0.1 GO:1904885 beta-catenin destruction complex assembly(GO:1904885)
0.0 0.0 GO:0046166 glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.0 0.2 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.0 0.1 GO:0048706 embryonic skeletal system development(GO:0048706)
0.0 0.0 GO:0048698 regulation of collateral sprouting in absence of injury(GO:0048696) negative regulation of collateral sprouting in absence of injury(GO:0048698)
0.0 0.1 GO:0021999 neural plate anterior/posterior regionalization(GO:0021999)
0.0 0.1 GO:2001171 positive regulation of ATP biosynthetic process(GO:2001171)
0.0 0.1 GO:0045347 negative regulation of MHC class II biosynthetic process(GO:0045347)
0.0 0.1 GO:0009149 pyrimidine nucleoside triphosphate catabolic process(GO:0009149) pyrimidine deoxyribonucleoside triphosphate catabolic process(GO:0009213)
0.0 0.0 GO:0006001 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.0 0.5 GO:0033572 transferrin transport(GO:0033572)
0.0 0.1 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.1 GO:0070166 enamel mineralization(GO:0070166)
0.0 0.1 GO:0015886 heme transport(GO:0015886)
0.0 0.0 GO:1902774 late endosome to lysosome transport(GO:1902774)
0.0 0.1 GO:0051382 kinetochore assembly(GO:0051382)
0.0 0.3 GO:0070987 error-free translesion synthesis(GO:0070987)
0.0 0.1 GO:0045008 depyrimidination(GO:0045008)
0.0 0.3 GO:0015936 coenzyme A metabolic process(GO:0015936)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:0005826 actomyosin contractile ring(GO:0005826)
0.2 0.9 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.1 0.9 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.1 0.5 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.1 0.8 GO:0033503 HULC complex(GO:0033503)
0.1 0.3 GO:0001534 radial spoke(GO:0001534)
0.1 0.5 GO:0033553 rDNA heterochromatin(GO:0033553)
0.1 0.8 GO:0070552 BRISC complex(GO:0070552)
0.1 0.1 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.1 1.1 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.1 0.6 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.1 0.5 GO:0002177 manchette(GO:0002177)
0.1 0.4 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.1 0.2 GO:0097447 dendritic tree(GO:0097447)
0.1 0.4 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.1 0.2 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.1 0.3 GO:0032279 axonemal microtubule(GO:0005879) asymmetric synapse(GO:0032279)
0.1 0.4 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.1 0.6 GO:0036157 outer dynein arm(GO:0036157)
0.1 0.3 GO:0033263 CORVET complex(GO:0033263)
0.1 0.6 GO:0000439 core TFIIH complex(GO:0000439)
0.0 0.6 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.1 GO:0019034 viral replication complex(GO:0019034)
0.0 0.2 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.0 0.2 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.0 0.3 GO:0044294 dendritic growth cone(GO:0044294)
0.0 0.3 GO:0005827 polar microtubule(GO:0005827)
0.0 0.3 GO:0097427 microtubule bundle(GO:0097427)
0.0 0.2 GO:0035838 growing cell tip(GO:0035838)
0.0 0.1 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.0 0.4 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 0.6 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 2.4 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.1 GO:0070761 pre-snoRNP complex(GO:0070761)
0.0 1.4 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.1 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.0 0.4 GO:0030914 STAGA complex(GO:0030914)
0.0 0.2 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.0 0.2 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.2 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 0.1 GO:0097135 cyclin E2-CDK2 complex(GO:0097135)
0.0 0.1 GO:0002169 3-methylcrotonyl-CoA carboxylase complex, mitochondrial(GO:0002169) methylcrotonoyl-CoA carboxylase complex(GO:1905202)
0.0 0.2 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.2 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.5 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.3 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.2 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559)
0.0 0.5 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.2 GO:0000306 extrinsic component of vacuolar membrane(GO:0000306)
0.0 0.1 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.0 0.2 GO:0030314 junctional membrane complex(GO:0030314)
0.0 0.2 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 0.3 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 0.2 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.0 0.2 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.1 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.0 0.1 GO:0031085 BLOC-3 complex(GO:0031085)
0.0 0.3 GO:0034709 methylosome(GO:0034709)
0.0 0.3 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.2 GO:0016589 NURF complex(GO:0016589)
0.0 0.3 GO:0097539 ciliary transition fiber(GO:0097539)
0.0 0.1 GO:0031510 SUMO activating enzyme complex(GO:0031510)
0.0 0.1 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.2 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0 0.1 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
0.0 0.1 GO:0034719 SMN-Sm protein complex(GO:0034719) Gemini of coiled bodies(GO:0097504)
0.0 0.2 GO:0071439 clathrin complex(GO:0071439)
0.0 0.2 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.0 0.2 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.0 GO:0031084 BLOC-2 complex(GO:0031084)
0.0 0.2 GO:0036038 MKS complex(GO:0036038)
0.0 0.0 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
0.0 0.1 GO:0042382 paraspeckles(GO:0042382)
0.0 0.1 GO:0044305 calyx of Held(GO:0044305)
0.0 0.0 GO:0070985 TFIIK complex(GO:0070985)
0.0 0.2 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0 0.1 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.3 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 0.1 GO:0030896 checkpoint clamp complex(GO:0030896)
0.0 0.1 GO:0032444 activin responsive factor complex(GO:0032444)
0.0 0.1 GO:0001740 Barr body(GO:0001740)
0.0 0.1 GO:0010369 chromocenter(GO:0010369)
0.0 0.1 GO:0031415 NatA complex(GO:0031415)
0.0 0.7 GO:0015030 Cajal body(GO:0015030)
0.0 0.1 GO:0016461 unconventional myosin complex(GO:0016461)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.2 0.6 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.2 0.5 GO:0004370 glycerol kinase activity(GO:0004370)
0.2 0.5 GO:0008746 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.1 0.5 GO:0043398 HLH domain binding(GO:0043398)
0.1 0.5 GO:0034602 oxoglutarate dehydrogenase (NAD+) activity(GO:0034602)
0.1 0.4 GO:0043739 G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739)
0.1 0.6 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.1 0.8 GO:0008732 glycine hydroxymethyltransferase activity(GO:0004372) threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.1 0.6 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.1 0.5 GO:0004850 uridine phosphorylase activity(GO:0004850)
0.1 0.3 GO:0030627 pre-mRNA 5'-splice site binding(GO:0030627)
0.1 0.4 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.1 0.4 GO:0032038 myosin II heavy chain binding(GO:0032038)
0.1 0.8 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 1.1 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 0.2 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
0.1 0.2 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.1 0.2 GO:0008859 exoribonuclease II activity(GO:0008859)
0.1 1.3 GO:0015250 water channel activity(GO:0015250)
0.1 0.4 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.1 0.9 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.1 0.3 GO:0008384 IkappaB kinase activity(GO:0008384)
0.1 0.5 GO:0004127 cytidylate kinase activity(GO:0004127)
0.1 0.6 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.1 0.4 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 0.2 GO:0070538 oleic acid binding(GO:0070538)
0.1 0.2 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.1 0.2 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.1 0.4 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.1 0.2 GO:0050309 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.1 0.3 GO:0003998 acylphosphatase activity(GO:0003998)
0.0 0.2 GO:1990189 peptide-serine-N-acetyltransferase activity(GO:1990189)
0.0 0.6 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.3 GO:0005119 smoothened binding(GO:0005119)
0.0 0.3 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.0 0.5 GO:0031419 cobalamin binding(GO:0031419)
0.0 2.0 GO:0005109 frizzled binding(GO:0005109)
0.0 0.1 GO:0015439 heme-transporting ATPase activity(GO:0015439)
0.0 0.3 GO:0044020 histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.0 0.2 GO:0004473 malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.0 0.1 GO:0032767 copper-dependent protein binding(GO:0032767)
0.0 0.3 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0 0.2 GO:0035651 AP-3 adaptor complex binding(GO:0035651)
0.0 0.2 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.0 0.9 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.4 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.1 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.0 0.1 GO:0035403 histone kinase activity (H3-T6 specific)(GO:0035403)
0.0 0.1 GO:0015230 FAD transmembrane transporter activity(GO:0015230)
0.0 0.3 GO:0019763 immunoglobulin receptor activity(GO:0019763)
0.0 0.2 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.0 0.1 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.0 0.1 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.0 0.1 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.0 0.2 GO:0001595 angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.0 0.1 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.0 0.1 GO:0005462 UDP-N-acetylglucosamine transmembrane transporter activity(GO:0005462)
0.0 0.2 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.3 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.1 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0 0.2 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.0 0.1 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.0 0.6 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.1 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.0 0.1 GO:0004844 uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.0 0.1 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.0 0.4 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.1 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.0 0.3 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.2 GO:0005353 fructose transmembrane transporter activity(GO:0005353)
0.0 0.1 GO:0000832 inositol-1,3,4,5,6-pentakisphosphate kinase activity(GO:0000827) inositol hexakisphosphate kinase activity(GO:0000828) inositol heptakisphosphate kinase activity(GO:0000829) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.0 0.1 GO:0008948 oxaloacetate decarboxylase activity(GO:0008948)
0.0 0.3 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.1 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.0 0.5 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.2 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.1 GO:0000702 oxidized base lesion DNA N-glycosylase activity(GO:0000702) oxidized purine nucleobase lesion DNA N-glycosylase activity(GO:0008534)
0.0 0.2 GO:0070569 uridylyltransferase activity(GO:0070569)
0.0 0.3 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.1 GO:0004485 methylcrotonoyl-CoA carboxylase activity(GO:0004485)
0.0 0.4 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.2 GO:0016742 hydroxymethyl-, formyl- and related transferase activity(GO:0016742)
0.0 1.2 GO:0050699 WW domain binding(GO:0050699)
0.0 0.2 GO:0004565 beta-galactosidase activity(GO:0004565)
0.0 0.2 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.1 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.0 0.5 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.1 GO:0004618 phosphoglycerate kinase activity(GO:0004618)
0.0 0.1 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.1 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.1 GO:0008240 tripeptidyl-peptidase activity(GO:0008240)
0.0 0.1 GO:0015526 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.0 0.1 GO:0042285 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0 0.1 GO:0051185 coenzyme transporter activity(GO:0051185)
0.0 0.1 GO:0016435 rRNA (guanine) methyltransferase activity(GO:0016435)
0.0 0.4 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 0.3 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.1 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.0 0.1 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.0 1.3 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.1 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.1 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.0 0.4 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.4 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.1 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.0 0.0 GO:0004730 pseudouridylate synthase activity(GO:0004730)
0.0 0.2 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.0 0.0 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.0 0.2 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.1 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292) hyaluronoglucuronidase activity(GO:0033906)
0.0 0.1 GO:0047820 D-glutamate cyclase activity(GO:0047820)
0.0 0.1 GO:0030305 beta-glucuronidase activity(GO:0004566) heparanase activity(GO:0030305)
0.0 0.1 GO:0034046 poly(G) binding(GO:0034046)
0.0 0.0 GO:0004827 proline-tRNA ligase activity(GO:0004827)
0.0 0.0 GO:0015925 galactosidase activity(GO:0015925)
0.0 0.0 GO:0010309 acireductone dioxygenase [iron(II)-requiring] activity(GO:0010309)
0.0 0.0 GO:0051139 metal ion:proton antiporter activity(GO:0051139)
0.0 0.1 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.1 GO:0043426 MRF binding(GO:0043426)
0.0 0.1 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 0.1 GO:0008172 S-methyltransferase activity(GO:0008172)
0.0 0.0 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.0 0.3 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.2 GO:0005402 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402)
0.0 0.1 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 0.4 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.1 GO:0070568 guanylyltransferase activity(GO:0070568)
0.0 0.1 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.0 GO:0004774 succinate-CoA ligase activity(GO:0004774)
0.0 0.5 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 0.4 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.2 GO:0015217 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.0 0.1 GO:0048256 flap endonuclease activity(GO:0048256)
0.0 0.0 GO:0002094 polyprenyltransferase activity(GO:0002094)
0.0 0.4 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.1 GO:0098821 BMP receptor activity(GO:0098821)
0.0 0.1 GO:0004832 valine-tRNA ligase activity(GO:0004832)
0.0 0.1 GO:0044388 small protein activating enzyme binding(GO:0044388)
0.0 0.6 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.0 GO:0102008 cytosolic dipeptidase activity(GO:0102008)
0.0 0.1 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 0.1 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0 0.4 GO:0070840 dynein complex binding(GO:0070840)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.6 PID_WNT_CANONICAL_PATHWAY Canonical Wnt signaling pathway
0.1 0.5 PID_FOXM1_PATHWAY FOXM1 transcription factor network
0.0 1.6 PID_ECADHERIN_STABILIZATION_PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.7 ST_MYOCYTE_AD_PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 0.8 PID_HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 1.5 PID_MTOR_4PATHWAY mTOR signaling pathway
0.0 0.2 SA_G2_AND_M_PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.9 PID_LKB1_PATHWAY LKB1 signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 2.2 REACTOME_SIGNALING_BY_HIPPO Genes involved in Signaling by Hippo
0.0 1.0 REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.4 REACTOME_CDC6_ASSOCIATION_WITH_THE_ORC_ORIGIN_COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 0.8 REACTOME_SYNTHESIS_OF_VERY_LONG_CHAIN_FATTY_ACYL_COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.6 REACTOME_RESOLUTION_OF_AP_SITES_VIA_THE_SINGLE_NUCLEOTIDE_REPLACEMENT_PATHWAY Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.0 0.5 REACTOME_PYRIMIDINE_CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.4 REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_PDH_COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.4 REACTOME_NFKB_IS_ACTIVATED_AND_SIGNALS_SURVIVAL Genes involved in NF-kB is activated and signals survival
0.0 0.7 REACTOME_FORMATION_OF_INCISION_COMPLEX_IN_GG_NER Genes involved in Formation of incision complex in GG-NER
0.0 0.6 REACTOME_SYNTHESIS_OF_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.6 REACTOME_BIOSYNTHESIS_OF_THE_N_GLYCAN_PRECURSOR_DOLICHOL_LIPID_LINKED_OLIGOSACCHARIDE_LLO_AND_TRANSFER_TO_A_NASCENT_PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.6 REACTOME_AMINO_ACID_SYNTHESIS_AND_INTERCONVERSION_TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.2 REACTOME_TRANSPORT_OF_MATURE_MRNA_DERIVED_FROM_AN_INTRONLESS_TRANSCRIPT Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.0 0.2 REACTOME_RAF_MAP_KINASE_CASCADE Genes involved in RAF/MAP kinase cascade
0.0 0.3 REACTOME_AKT_PHOSPHORYLATES_TARGETS_IN_THE_CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.4 REACTOME_METABOLISM_OF_POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.1 REACTOME_FATTY_ACYL_COA_BIOSYNTHESIS Genes involved in Fatty Acyl-CoA Biosynthesis
0.0 0.5 REACTOME_TRANSFERRIN_ENDOCYTOSIS_AND_RECYCLING Genes involved in Transferrin endocytosis and recycling
0.0 0.9 REACTOME_GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.3 REACTOME_PKA_MEDIATED_PHOSPHORYLATION_OF_CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 0.2 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_EARLY_ENDOSOME_MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.2 REACTOME_ACTIVATION_OF_IRF3_IRF7_MEDIATED_BY_TBK1_IKK_EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.0 0.1 REACTOME_VITAMIN_B5_PANTOTHENATE_METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism