Motif ID: MEF2D_MEF2A
Z-value: 0.629


Transcription factors associated with MEF2D_MEF2A:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
MEF2A | ENSG00000068305.13 | MEF2A |
MEF2D | ENSG00000116604.13 | MEF2D |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
MEF2A | hg19_v2_chr15_+_100106155_100106243 | -0.29 | 1.7e-01 | Click! |
MEF2D | hg19_v2_chr1_-_156460391_156460417 | 0.17 | 4.3e-01 | Click! |
Top targets:
Showing 1 to 20 of 200 entries
Gene overrepresentation in biological_process category:
Showing 1 to 20 of 77 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.0 | 1.4 | GO:0010923 | negative regulation of phosphatase activity(GO:0010923) |
0.2 | 1.0 | GO:0035995 | detection of muscle stretch(GO:0035995) |
0.1 | 0.9 | GO:0014883 | transition between fast and slow fiber(GO:0014883) |
0.0 | 0.9 | GO:0003009 | skeletal muscle contraction(GO:0003009) |
0.0 | 0.7 | GO:1904659 | hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659) |
0.1 | 0.6 | GO:0021797 | forebrain anterior/posterior pattern specification(GO:0021797) |
0.0 | 0.6 | GO:1903861 | positive regulation of dendrite extension(GO:1903861) |
0.1 | 0.5 | GO:0019530 | taurine metabolic process(GO:0019530) |
0.0 | 0.5 | GO:0070050 | neuron cellular homeostasis(GO:0070050) |
0.1 | 0.4 | GO:0000117 | regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117) |
0.1 | 0.4 | GO:1901860 | positive regulation of mitochondrial DNA metabolic process(GO:1901860) |
0.0 | 0.4 | GO:0019227 | neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870) |
0.0 | 0.4 | GO:0090050 | peptidyl-lysine deacetylation(GO:0034983) positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050) |
0.0 | 0.4 | GO:0001502 | cartilage condensation(GO:0001502) |
0.0 | 0.4 | GO:0015695 | organic cation transport(GO:0015695) |
0.1 | 0.3 | GO:1903225 | negative regulation of endodermal cell differentiation(GO:1903225) |
0.1 | 0.3 | GO:0010752 | regulation of cGMP-mediated signaling(GO:0010752) regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538) |
0.1 | 0.3 | GO:0060023 | soft palate development(GO:0060023) |
0.0 | 0.3 | GO:1900748 | positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748) |
0.0 | 0.3 | GO:1902866 | regulation of retina development in camera-type eye(GO:1902866) |
Gene overrepresentation in cellular_component category:
Showing 1 to 20 of 34 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 1.7 | GO:0005861 | troponin complex(GO:0005861) |
0.0 | 0.8 | GO:0017146 | NMDA selective glutamate receptor complex(GO:0017146) |
0.0 | 0.5 | GO:0032045 | guanyl-nucleotide exchange factor complex(GO:0032045) |
0.0 | 0.5 | GO:0005859 | muscle myosin complex(GO:0005859) |
0.0 | 0.5 | GO:0032982 | myosin filament(GO:0032982) |
0.0 | 0.4 | GO:0032593 | insulin-responsive compartment(GO:0032593) |
0.0 | 0.4 | GO:0032039 | integrator complex(GO:0032039) |
0.0 | 0.4 | GO:0097440 | apical dendrite(GO:0097440) |
0.0 | 0.4 | GO:0001891 | phagocytic cup(GO:0001891) |
0.1 | 0.3 | GO:0005588 | collagen type V trimer(GO:0005588) |
0.1 | 0.3 | GO:0030936 | collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936) |
0.1 | 0.3 | GO:0045160 | myosin I complex(GO:0045160) |
0.0 | 0.3 | GO:0030893 | meiotic cohesin complex(GO:0030893) |
0.0 | 0.3 | GO:0098645 | network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) |
0.0 | 0.3 | GO:0016012 | sarcoglycan complex(GO:0016012) |
0.0 | 0.3 | GO:0005583 | fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643) |
0.0 | 0.3 | GO:0097550 | transcriptional preinitiation complex(GO:0097550) |
0.0 | 0.3 | GO:0031588 | nucleotide-activated protein kinase complex(GO:0031588) |
0.1 | 0.2 | GO:0042022 | interleukin-12 receptor complex(GO:0042022) |
0.1 | 0.2 | GO:0031674 | I band(GO:0031674) |
Gene overrepresentation in molecular_function category:
Showing 1 to 20 of 60 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.0 | 1.1 | GO:0030742 | GTP-dependent protein binding(GO:0030742) |
0.1 | 0.8 | GO:0051373 | FATZ binding(GO:0051373) |
0.0 | 0.7 | GO:0055056 | D-glucose transmembrane transporter activity(GO:0055056) |
0.2 | 0.6 | GO:0030899 | calcium-dependent ATPase activity(GO:0030899) |
0.0 | 0.6 | GO:0001205 | transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205) |
0.1 | 0.5 | GO:0004972 | NMDA glutamate receptor activity(GO:0004972) |
0.1 | 0.5 | GO:0031433 | telethonin binding(GO:0031433) |
0.0 | 0.5 | GO:0016290 | palmitoyl-CoA hydrolase activity(GO:0016290) |
0.0 | 0.4 | GO:0031078 | histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041) |
0.0 | 0.4 | GO:0005247 | voltage-gated chloride channel activity(GO:0005247) |
0.0 | 0.4 | GO:0008519 | ammonium transmembrane transporter activity(GO:0008519) |
0.0 | 0.4 | GO:0004602 | glutathione peroxidase activity(GO:0004602) |
0.0 | 0.4 | GO:0048020 | CCR chemokine receptor binding(GO:0048020) |
0.1 | 0.3 | GO:0043423 | 3-phosphoinositide-dependent protein kinase binding(GO:0043423) |
0.1 | 0.3 | GO:0042835 | BRE binding(GO:0042835) |
0.0 | 0.3 | GO:0038052 | RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052) |
0.0 | 0.3 | GO:0030020 | extracellular matrix structural constituent conferring tensile strength(GO:0030020) |
0.0 | 0.3 | GO:0042975 | peroxisome proliferator activated receptor binding(GO:0042975) |
0.0 | 0.3 | GO:0004679 | AMP-activated protein kinase activity(GO:0004679) |
0.0 | 0.3 | GO:0019992 | diacylglycerol binding(GO:0019992) |
Gene overrepresentation in C2:CP category:
Showing 1 to 3 of 3 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.0 | 1.3 | NABA_COLLAGENS | Genes encoding collagen proteins |
0.0 | 0.8 | PID_INSULIN_GLUCOSE_PATHWAY | Insulin-mediated glucose transport |
0.0 | 0.8 | PID_HDAC_CLASSII_PATHWAY | Signaling events mediated by HDAC Class II |
Gene overrepresentation in C2:CP:REACTOME category:
Showing 1 to 11 of 11 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.0 | 1.9 | REACTOME_STRIATED_MUSCLE_CONTRACTION | Genes involved in Striated Muscle Contraction |
0.0 | 1.2 | REACTOME_COLLAGEN_FORMATION | Genes involved in Collagen formation |
0.0 | 0.7 | REACTOME_FACILITATIVE_NA_INDEPENDENT_GLUCOSE_TRANSPORTERS | Genes involved in Facilitative Na+-independent glucose transporters |
0.0 | 0.5 | REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_7ALPHA_HYDROXYCHOLESTEROL | Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol |
0.0 | 0.5 | REACTOME_RAS_ACTIVATION_UOPN_CA2_INFUX_THROUGH_NMDA_RECEPTOR | Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor |
0.0 | 0.3 | REACTOME_DOWNSTREAM_SIGNALING_EVENTS_OF_B_CELL_RECEPTOR_BCR | Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR) |
0.0 | 0.3 | REACTOME_REGULATION_OF_RHEB_GTPASE_ACTIVITY_BY_AMPK | Genes involved in Regulation of Rheb GTPase activity by AMPK |
0.0 | 0.3 | REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA | Genes involved in Circadian Repression of Expression by REV-ERBA |
0.0 | 0.3 | REACTOME_TIE2_SIGNALING | Genes involved in Tie2 Signaling |
0.0 | 0.2 | REACTOME_PURINE_CATABOLISM | Genes involved in Purine catabolism |
0.0 | 0.1 | REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_24_HYDROXYCHOLESTEROL | Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol |